# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/pg00933y4.fasta.nr -Q ../query/KIAA1410.ptfa /cdna2/lib/nr/nr 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 KIAA1410, 4293 aa vs /cdna2/lib/nr/nr library 2693465022 residues in 7827732 sequences statistics sampled from 60000 to 7824924 sequences Expectation_n fit: rho(ln(x))= 6.3202+/-0.000187; mu= 12.8889+/- 0.010 mean_var=103.3365+/-20.550, 0's: 34 Z-trim: 51 B-trim: 9 in 2/64 Lambda= 0.126167 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 50, opt: 38, open/ext: -10/-2, width: 16 The best scores are: opt bits E(7827732) gi|197927452|ref|NP_056327.4| dynein, axonemal, he (4265) 28411 5184.4 0 gi|172044682|sp|Q9P2D7.3|DYH1_HUMAN RecName: Full= (4330) 20773 3794.1 0 gi|119585621|gb|EAW65217.1| dynein, axonemal, heav (4323) 20418 3729.5 0 gi|109039223|ref|XP_001085984.1| PREDICTED: simila (4313) 20128 3676.7 0 gi|119585623|gb|EAW65219.1| dynein, axonemal, heav (4334) 16003 2925.9 0 gi|73985528|ref|XP_533802.2| PREDICTED: similar to (4259) 14387 2631.7 0 gi|119585622|gb|EAW65218.1| dynein, axonemal, heav (2455) 12338 2258.6 0 gi|148692857|gb|EDL24804.1| mCG3819 [Mus musculus] (3614) 11297 2069.2 0 gi|149034184|gb|EDL88954.1| rCG42293 [Rattus norve (1950) 11269 2064.0 0 gi|163777893|gb|EDQ91509.1| predicted protein [Mon (4070) 11074 2028.7 0 gi|118098340|ref|XP_424606.2| PREDICTED: similar t (4046) 10250 1878.7 0 gi|126334332|ref|XP_001377077.1| PREDICTED: simila (4099) 10189 1867.6 0 gi|109462780|ref|XP_001079121.1| PREDICTED: simila (4099) 10125 1855.9 0 gi|194219167|ref|XP_001491903.2| PREDICTED: dynein (4084) 10044 1841.2 0 gi|73958899|ref|XP_547101.2| PREDICTED: similar to (4135) 10010 1835.0 0 gi|182637561|sp|Q8BW94.2|DYH3_MOUSE RecName: Full= (4083) 9976 1828.8 0 gi|94381000|ref|XP_355934.5| PREDICTED: similar to (4095) 9976 1828.8 0 gi|114661409|ref|XP_510868.2| PREDICTED: dynein, a (4116) 9954 1824.8 0 gi|74762616|sp|Q8TD57.1|DYH3_HUMAN RecName: Full=D (4116) 9949 1823.9 0 gi|210089178|gb|EEA37492.1| hypothetical protein B (3777) 9937 1821.7 0 gi|73985341|ref|XP_541831.2| PREDICTED: similar to (4017) 9896 1814.3 0 gi|198426988|ref|XP_002120431.1| PREDICTED: simila (3957) 9875 1810.4 0 gi|121933964|gb|AAI27558.1| Dnah1 protein [Xenopus (1928) 9869 1809.1 0 gi|166796749|gb|AAI59124.1| Dnah1 protein [Xenopus (2037) 9869 1809.1 0 gi|190584868|gb|EDV24937.1| hypothetical protein T (3863) 9857 1807.2 0 gi|118096878|ref|XP_414346.2| PREDICTED: similar t (4044) 9850 1805.9 0 gi|109503694|ref|XP_001057601.1| PREDICTED: simila (3968) 9825 1801.3 0 gi|119585743|gb|EAW65339.1| hCG1779312, isoform CR (3943) 9823 1801.0 0 gi|110760932|ref|XP_393804.3| PREDICTED: similar t (3797) 9722 1782.6 0 gi|189525347|ref|XP_001920013.1| PREDICTED: simila (2803) 9626 1765.0 0 gi|162681522|gb|EDQ67948.1| predicted protein [Phy (3193) 9310 1707.5 0 gi|134066071|emb|CAM43859.1| dynein heavy chain, p (4170) 9216 1690.5 0 gi|89302981|gb|EAS00969.1| Dynein heavy chain fami (4435) 9171 1682.3 0 gi|149265372|ref|XP_981204.2| PREDICTED: dynein, a (3099) 9115 1672.0 0 gi|70834276|gb|EAN79778.1| dynein heavy chain, put (4152) 8981 1647.7 0 gi|119585619|gb|EAW65215.1| dynein, axonemal, heav (4383) 8835 1621.2 0 gi|212511937|gb|EEB14797.1| dynein beta chain, cil (4014) 8803 1615.3 0 gi|190579625|gb|EDV19716.1| hypothetical protein T (4155) 8630 1583.8 0 gi|108869187|gb|EAT33412.1| dynein heavy chain [Ae (3930) 8625 1582.9 0 gi|91093104|ref|XP_970084.1| PREDICTED: similar to (3809) 8586 1575.8 0 gi|110761320|ref|XP_396548.3| PREDICTED: similar t (3828) 8574 1573.6 0 gi|116122759|gb|EAA13034.3| AGAP011441-PA [Anophel (3938) 8520 1563.8 0 gi|167874268|gb|EDS37651.1| ciliary dynein heavy c (3930) 8516 1563.1 0 gi|215276939|dbj|BAE19786.3| dynein heavy chain 9 (4149) 8433 1548.0 0 gi|156221767|gb|EDO42618.1| predicted protein [Nem (2033) 8377 1537.6 0 gi|221103047|ref|XP_002170539.1| PREDICTED: hypoth (2399) 8342 1531.2 0 gi|68129742|emb|CAJ09048.1| dynein heavy chain, pu (4172) 8305 1524.7 0 gi|134073878|emb|CAM72617.1| dynein heavy chain, p (4172) 8288 1521.6 0 gi|109503005|ref|XP_341393.3| PREDICTED: similar t (3971) 8245 1513.7 0 gi|119585744|gb|EAW65340.1| hCG1779312, isoform CR (3897) 8241 1513.0 0 >>gi|197927452|ref|NP_056327.4| dynein, axonemal, heavy (4265 aa) initn: 28411 init1: 28411 opt: 28411 Z-score: 27933.9 bits: 5184.4 E(): 0 Smith-Waterman score: 28411; 100.000% identity (100.000% similar) in 4265 aa overlap (29-4293:1-4265) 10 20 30 40 50 60 KIAA14 NHSLDSGKVAPPSGLEGSFGWGISLRSSMEQPNSKGYSLGRTPQGPECSSAPAVQVGTHR :::::::::::::::::::::::::::::::: gi|197 MEQPNSKGYSLGRTPQGPECSSAPAVQVGTHR 10 20 30 70 80 90 100 110 120 KIAA14 GLEYNPGKILPGSDYGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 GLEYNPGKILPGSDYGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLM 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 KQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQ 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 CIGSTTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQLLFSQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 CIGSTTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQLLFSQG 160 170 180 190 200 210 250 260 270 280 290 300 KIAA14 IDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLKVFDNEDFDCRTPREWINMGLEPGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 IDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLKVFDNEDFDCRTPREWINMGLEPGSLD 220 230 240 250 260 270 310 320 330 340 350 360 KIAA14 RKPVPGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 RKPVPGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEM 280 290 300 310 320 330 370 380 390 400 410 420 KIAA14 GRPILNAGVTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEALLLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 GRPILNAGVTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEALLLYN 340 350 360 370 380 390 430 440 450 460 470 480 KIAA14 LYVDCMPSDGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDYERSMNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LYVDCMPSDGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDYERSMNKI 400 410 420 430 440 450 490 500 510 520 530 540 KIAA14 NFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 NFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITA 460 470 480 490 500 510 550 560 570 580 590 600 KIAA14 LSKVRAECNKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKVAMRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LSKVRAECNKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKVAMRSS 520 530 540 550 560 570 610 620 630 640 650 660 KIAA14 LRDMSKGWYNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LRDMSKGWYNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCS 580 590 600 610 620 630 670 680 690 700 710 720 KIAA14 VLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 VLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGIL 640 650 660 670 680 690 730 740 750 760 770 780 KIAA14 ATHAVPQLEKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 ATHAVPQLEKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYR 700 710 720 730 740 750 790 800 810 820 830 840 KIAA14 KYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 KYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDN 760 770 780 790 800 810 850 860 870 880 890 900 KIAA14 VKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 VKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMK 820 830 840 850 860 870 910 920 930 940 950 960 KIAA14 GIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 GIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHV 880 890 900 910 920 930 970 980 990 1000 1010 1020 KIAA14 EDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 EDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQL 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 KIAA14 AMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 AMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQ 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 KIAA14 LEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWE 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 KIAA14 TLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 TLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTI 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 KIAA14 LFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQE 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 KIAA14 VLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 VLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCS 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 KIAA14 DLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 DLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPH 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 KIAA14 LRKCFENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LRKCFENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDI 1360 1370 1380 1390 1400 1410 1450 1460 1470 1480 1490 1500 KIAA14 IEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 IEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSD 1420 1430 1440 1450 1460 1470 1510 1520 1530 1540 1550 1560 KIAA14 LVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDL 1480 1490 1500 1510 1520 1530 1570 1580 1590 1600 1610 1620 KIAA14 YIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 YIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTK 1540 1550 1560 1570 1580 1590 1630 1640 1650 1660 1670 1680 KIAA14 DLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 DLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITT 1600 1610 1620 1630 1640 1650 1690 1700 1710 1720 1730 1740 KIAA14 IQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 IQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYA 1660 1670 1680 1690 1700 1710 1750 1760 1770 1780 1790 1800 KIAA14 MITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKREN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 MITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKREN 1720 1730 1740 1750 1760 1770 1810 1820 1830 1840 1850 1860 KIAA14 PSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 PSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRN 1780 1790 1800 1810 1820 1830 1870 1880 1890 1900 1910 1920 KIAA14 SNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 SNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGM 1840 1850 1860 1870 1880 1890 1930 1940 1950 1960 1970 1980 KIAA14 YEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 YEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVD 1900 1910 1920 1930 1940 1950 1990 2000 2010 2020 2030 2040 KIAA14 AIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 AIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSI 1960 1970 1980 1990 2000 2010 2050 2060 2070 2080 2090 2100 KIAA14 LGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLL 2020 2030 2040 2050 2060 2070 2110 2120 2130 2140 2150 2160 KIAA14 KLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 KLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLR 2080 2090 2100 2110 2120 2130 2170 2180 2190 2200 2210 2220 KIAA14 LKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVP 2140 2150 2160 2170 2180 2190 2230 2240 2250 2260 2270 2280 KIAA14 DTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 DTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISH 2200 2210 2220 2230 2240 2250 2290 2300 2310 2320 2330 2340 KIAA14 FLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 FLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIEL 2260 2270 2280 2290 2300 2310 2350 2360 2370 2380 2390 2400 KIAA14 LRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEV 2320 2330 2340 2350 2360 2370 2410 2420 2430 2440 2450 2460 KIAA14 SKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 SKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPA 2380 2390 2400 2410 2420 2430 2470 2480 2490 2500 2510 2520 KIAA14 KSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 KSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQL 2440 2450 2460 2470 2480 2490 2530 2540 2550 2560 2570 2580 KIAA14 LKRCMEQWEVTFNKVCPFQPILYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LKRCMEQWEVTFNKVCPFQPILYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQIN 2500 2510 2520 2530 2540 2550 2590 2600 2610 2620 2630 2640 KIAA14 TAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 TAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIEL 2560 2570 2580 2590 2600 2610 2650 2660 2670 2680 2690 2700 KIAA14 SKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 SKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTA 2620 2630 2640 2650 2660 2670 2710 2720 2730 2740 2750 2760 KIAA14 DEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 DEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPS 2680 2690 2700 2710 2720 2730 2770 2780 2790 2800 2810 2820 KIAA14 LVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEY 2740 2750 2760 2770 2780 2790 2830 2840 2850 2860 2870 2880 KIAA14 LAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQED 2800 2810 2820 2830 2840 2850 2890 2900 2910 2920 2930 2940 KIAA14 LESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKD 2860 2870 2880 2890 2900 2910 2950 2960 2970 2980 2990 3000 KIAA14 LDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 LDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPG 2920 2930 2940 2950 2960 2970 3010 3020 3030 3040 3050 3060 KIAA14 TKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 TKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKA 2980 2990 3000 3010 3020 3030 3070 3080 3090 3100 3110 3120 KIAA14 CTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 CTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQ 3040 3050 3060 3070 3080 3090 3130 3140 3150 3160 3170 3180 KIAA14 AKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 AKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVL 3100 3110 3120 3130 3140 3150 3190 3200 3210 3220 3230 3240 KIAA14 VAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 VAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLP 3160 3170 3180 3190 3200 3210 3250 3260 3270 3280 3290 3300 KIAA14 NDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 NDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIR 3220 3230 3240 3250 3260 3270 3310 3320 3330 3340 3350 3360 KIAA14 FGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 FGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPH 3280 3290 3300 3310 3320 3330 3370 3380 3390 3400 3410 3420 KIAA14 YTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 YTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIED 3340 3350 3360 3370 3380 3390 3430 3440 3450 3460 3470 3480 KIAA14 QILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 QILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIR 3400 3410 3420 3430 3440 3450 3490 3500 3510 3520 3530 3540 KIAA14 TQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 TQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYSN 3460 3470 3480 3490 3500 3510 3550 3560 3570 3580 3590 3600 KIAA14 VCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPDWLSDRAWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 VCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPDWLSDRAWR 3520 3530 3540 3550 3560 3570 3610 3620 3630 3640 3650 3660 KIAA14 DILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 DILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLR 3580 3590 3600 3610 3620 3630 3670 3680 3690 3700 3710 3720 KIAA14 GDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 GDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAE 3640 3650 3660 3670 3680 3690 3730 3740 3750 3760 3770 3780 KIAA14 EMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 EMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPD 3700 3710 3720 3730 3740 3750 3790 3800 3810 3820 3830 3840 KIAA14 KVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 KVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVM 3760 3770 3780 3790 3800 3810 3850 3860 3870 3880 3890 3900 KIAA14 EFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 EFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVL 3820 3830 3840 3850 3860 3870 3910 3920 3930 3940 3950 3960 KIAA14 KYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 KYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYL 3880 3890 3900 3910 3920 3930 3970 3980 3990 4000 4010 4020 KIAA14 SYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 SYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVT 3940 3950 3960 3970 3980 3990 4030 4040 4050 4060 4070 4080 KIAA14 QNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 QNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGL 4000 4010 4020 4030 4040 4050 4090 4100 4110 4120 4130 4140 KIAA14 VVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 VVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVF 4060 4070 4080 4090 4100 4110 4150 4160 4170 4180 4190 4200 KIAA14 WISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 WISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLE 4120 4130 4140 4150 4160 4170 4210 4220 4230 4240 4250 4260 KIAA14 GARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|197 GARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTG 4180 4190 4200 4210 4220 4230 4270 4280 4290 KIAA14 HSTNYVIAVEIPTHQPQRHWIKRGVALICALDY ::::::::::::::::::::::::::::::::: gi|197 HSTNYVIAVEIPTHQPQRHWIKRGVALICALDY 4240 4250 4260 >>gi|172044682|sp|Q9P2D7.3|DYH1_HUMAN RecName: Full=Dyne (4330 aa) initn: 20772 init1: 20772 opt: 20773 Z-score: 20420.1 bits: 3794.1 E(): 0 Smith-Waterman score: 28271; 98.499% identity (98.499% similar) in 4330 aa overlap (29-4293:1-4330) 10 20 30 40 50 60 KIAA14 NHSLDSGKVAPPSGLEGSFGWGISLRSSMEQPNSKGYSLGRTPQGPECSSAPAVQVGTHR :::::::::::::::::::::::::::::::: gi|172 MEQPNSKGYSLGRTPQGPECSSAPAVQVGTHR 10 20 30 70 80 90 100 110 120 KIAA14 GLEYNPGKILPGSDYGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 GLEYNPGKILPGSDYGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLM 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 KQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQ 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 CIGSTTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQLLFSQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 CIGSTTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQLLFSQG 160 170 180 190 200 210 250 260 270 280 290 300 KIAA14 IDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLKVFDNEDFDCRTPREWINMGLEPGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 IDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLKVFDNEDFDCRTPREWINMGLEPGSLD 220 230 240 250 260 270 310 320 330 340 350 360 KIAA14 RKPVPGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 RKPVPGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEM 280 290 300 310 320 330 370 380 390 400 410 420 KIAA14 GRPILNAGVTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEALLLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 GRPILNAGVTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEALLLYN 340 350 360 370 380 390 430 440 450 460 470 480 KIAA14 LYVDCMPSDGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDYERSMNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LYVDCMPSDGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDYERSMNKI 400 410 420 430 440 450 490 500 510 520 530 540 KIAA14 NFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 NFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITA 460 470 480 490 500 510 550 560 570 580 590 600 KIAA14 LSKVRAECNKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKVAMRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LSKVRAECNKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKVAMRSS 520 530 540 550 560 570 610 620 630 640 650 660 KIAA14 LRDMSKGWYNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LRDMSKGWYNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCS 580 590 600 610 620 630 670 680 690 700 710 720 KIAA14 VLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 VLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGIL 640 650 660 670 680 690 730 740 750 760 770 780 KIAA14 ATHAVPQLEKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 ATHAVPQLEKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYR 700 710 720 730 740 750 790 800 810 820 830 840 KIAA14 KYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 KYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDN 760 770 780 790 800 810 850 860 870 880 890 900 KIAA14 VKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 VKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMK 820 830 840 850 860 870 910 920 930 940 950 960 KIAA14 GIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 GIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHV 880 890 900 910 920 930 970 980 990 1000 1010 1020 KIAA14 EDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 EDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQL 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 KIAA14 AMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 AMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQ 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 KIAA14 LEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWE 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 KIAA14 TLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 TLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTI 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 KIAA14 LFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQE 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 KIAA14 VLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 VLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCS 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 KIAA14 DLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 DLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPH 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 KIAA14 LRKCFENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LRKCFENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDI 1360 1370 1380 1390 1400 1410 1450 1460 1470 1480 1490 1500 KIAA14 IEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 IEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSD 1420 1430 1440 1450 1460 1470 1510 1520 1530 1540 1550 1560 KIAA14 LVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDL 1480 1490 1500 1510 1520 1530 1570 1580 1590 1600 1610 1620 KIAA14 YIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 YIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTK 1540 1550 1560 1570 1580 1590 1630 1640 1650 1660 1670 1680 KIAA14 DLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 DLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITT 1600 1610 1620 1630 1640 1650 1690 1700 1710 1720 1730 1740 KIAA14 IQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 IQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYA 1660 1670 1680 1690 1700 1710 1750 1760 1770 1780 1790 1800 KIAA14 MITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKREN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 MITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKREN 1720 1730 1740 1750 1760 1770 1810 1820 1830 1840 1850 1860 KIAA14 PSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 PSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRN 1780 1790 1800 1810 1820 1830 1870 1880 1890 1900 1910 1920 KIAA14 SNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 SNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGM 1840 1850 1860 1870 1880 1890 1930 1940 1950 1960 1970 1980 KIAA14 YEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 YEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVD 1900 1910 1920 1930 1940 1950 1990 2000 2010 2020 2030 2040 KIAA14 AIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 AIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSI 1960 1970 1980 1990 2000 2010 2050 2060 2070 2080 2090 2100 KIAA14 LGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLL 2020 2030 2040 2050 2060 2070 2110 2120 2130 2140 2150 2160 KIAA14 KLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 KLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLR 2080 2090 2100 2110 2120 2130 2170 2180 2190 2200 2210 2220 KIAA14 LKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVP 2140 2150 2160 2170 2180 2190 2230 2240 2250 2260 2270 2280 KIAA14 DTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 DTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISH 2200 2210 2220 2230 2240 2250 2290 2300 2310 2320 2330 2340 KIAA14 FLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 FLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIEL 2260 2270 2280 2290 2300 2310 2350 2360 2370 2380 2390 2400 KIAA14 LRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEV 2320 2330 2340 2350 2360 2370 2410 2420 2430 2440 2450 2460 KIAA14 SKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 SKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPA 2380 2390 2400 2410 2420 2430 2470 2480 2490 2500 2510 2520 KIAA14 KSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 KSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQL 2440 2450 2460 2470 2480 2490 2530 2540 2550 2560 2570 2580 KIAA14 LKRCMEQWEVTFNKVCPFQPILYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LKRCMEQWEVTFNKVCPFQPILYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQIN 2500 2510 2520 2530 2540 2550 2590 2600 2610 2620 2630 2640 KIAA14 TAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 TAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIEL 2560 2570 2580 2590 2600 2610 2650 2660 2670 2680 2690 2700 KIAA14 SKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 SKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTA 2620 2630 2640 2650 2660 2670 2710 2720 2730 2740 2750 2760 KIAA14 DEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 DEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPS 2680 2690 2700 2710 2720 2730 2770 2780 2790 2800 2810 2820 KIAA14 LVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEY 2740 2750 2760 2770 2780 2790 2830 2840 2850 2860 2870 2880 KIAA14 LAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQED 2800 2810 2820 2830 2840 2850 2890 2900 2910 2920 2930 2940 KIAA14 LESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKD 2860 2870 2880 2890 2900 2910 2950 2960 2970 2980 2990 3000 KIAA14 LDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPG 2920 2930 2940 2950 2960 2970 3010 3020 3030 3040 3050 3060 KIAA14 TKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 TKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKA 2980 2990 3000 3010 3020 3030 3070 3080 3090 3100 3110 3120 KIAA14 CTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 CTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQ 3040 3050 3060 3070 3080 3090 3130 3140 KIAA14 AKYRECITKKEELELKCEQCEQRLGRAGK------------------------------- ::::::::::::::::::::::::::::: gi|172 AKYRECITKKEELELKCEQCEQRLGRAGKVRTLLLQGLQAGPAQTGARKDQGAGGSWGGC 3100 3110 3120 3130 3140 3150 3150 3160 3170 KIAA14 ----------------------------------LINGLSDEKVRWQETVENLQYMLNNI :::::::::::::::::::::::::: gi|172 PHPLPGNPGATVGRASPRPLAQPPRAHPTGLPLQLINGLSDEKVRWQETVENLQYMLNNI 3160 3170 3180 3190 3200 3210 3180 3190 3200 3210 3220 3230 KIAA14 SGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 SGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQ 3220 3230 3240 3250 3260 3270 3240 3250 3260 3270 3280 3290 KIAA14 IAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 IAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSM 3280 3290 3300 3310 3320 3330 3300 3310 3320 3330 3340 3350 KIAA14 ENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 ENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTK 3340 3350 3360 3370 3380 3390 3360 3370 3380 3390 3400 3410 KIAA14 LPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQEL 3400 3410 3420 3430 3440 3450 3420 3430 3440 3450 3460 3470 KIAA14 KDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 KDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYI 3460 3470 3480 3490 3500 3510 3480 3490 3500 3510 3520 3530 KIAA14 PVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 PVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTY 3520 3530 3540 3550 3560 3570 3540 3550 3560 3570 3580 3590 KIAA14 SLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPDWLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 SLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPDWLS 3580 3590 3600 3610 3620 3630 3600 3610 3620 3630 3640 3650 KIAA14 DRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 DRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLV 3640 3650 3660 3670 3680 3690 3660 3670 3680 3690 3700 3710 KIAA14 LRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADL 3700 3710 3720 3730 3740 3750 3720 3730 3740 3750 3760 3770 KIAA14 YKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 YKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIE 3760 3770 3780 3790 3800 3810 3780 3790 3800 3810 3820 3830 KIAA14 HINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 HINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNS 3820 3830 3840 3850 3860 3870 3840 3850 3860 3870 3880 3890 KIAA14 CHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 CHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDI 3880 3890 3900 3910 3920 3930 3900 3910 3920 3930 3940 3950 KIAA14 PYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 PYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYD 3940 3950 3960 3970 3980 3990 3960 3970 3980 3990 4000 4010 KIAA14 LHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGREEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 LHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGREEI 4000 4010 4020 4030 4040 4050 4020 4030 4040 4050 4060 4070 KIAA14 VEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 VEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLK 4060 4070 4080 4090 4100 4110 4080 4090 4100 4110 4120 4130 KIAA14 ALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 ALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDG 4120 4130 4140 4150 4160 4170 4140 4150 4160 4170 4180 4190 KIAA14 IPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 IPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIH 4180 4190 4200 4210 4220 4230 4200 4210 4220 4230 4240 4250 KIAA14 GLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|172 GLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGT 4240 4250 4260 4270 4280 4290 4260 4270 4280 4290 KIAA14 LSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALICALDY :::::::::::::::::::::::::::::::::::::: gi|172 LSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALICALDY 4300 4310 4320 4330 >>gi|119585621|gb|EAW65217.1| dynein, axonemal, heavy po (4323 aa) initn: 22349 init1: 17049 opt: 20418 Z-score: 20070.9 bits: 3729.5 E(): 0 Smith-Waterman score: 27824; 96.881% identity (96.927% similar) in 4361 aa overlap (29-4293:1-4323) 10 20 30 40 50 60 KIAA14 NHSLDSGKVAPPSGLEGSFGWGISLRSSMEQPNSKGYSLGRTPQGPECSSAPAVQVGTHR :::::::::::::::::::::::::::::::: gi|119 MEQPNSKGYSLGRTPQGPECSSAPAVQVGTHR 10 20 30 70 80 90 100 110 120 KIAA14 GLEYNPGKILPGSDYGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GLEYNPGKILPGSDYGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLM 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQ 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 CIGSTTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQLLFSQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 CIGSTTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQLLFSQG 160 170 180 190 200 210 250 260 270 KIAA14 IDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLK-------------------------- :::::::::::::::::::::::::::::::::: gi|119 IDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLKPVCLASASVPPMGNLDAAQLDCGVSS 220 230 240 250 260 270 280 290 300 310 KIAA14 -------VFDNEDFDCRTPREWINMGLEPGSLDRKPVPGKALLPTDDFLGH--------- :::::::::::::::::::::::::::::::::::::::::::: gi|119 LTSARLRVFDNEDFDCRTPREWINMGLEPGSLDRKPVPGKALLPTDDFLGHGLPQRLWRL 280 290 300 310 320 330 320 330 340 350 360 KIAA14 ----------EDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRPILNAG :::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SHFLLWKAVPEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRPILNAG 340 350 360 370 380 390 370 380 390 400 410 420 KIAA14 VTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEALLLYNLYVDCMPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEALLLYNLYVDCMPS 400 410 420 430 440 450 430 440 450 460 470 480 KIAA14 DGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSS 460 470 480 490 500 510 490 500 510 520 530 540 KIAA14 KPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAEC 520 530 540 550 560 570 550 560 570 580 590 600 KIAA14 NKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGW 580 590 600 610 620 630 610 620 630 640 650 660 KIAA14 YNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDM 640 650 660 670 680 690 670 680 690 700 710 720 KIAA14 VWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQL 700 710 720 730 740 750 730 740 750 760 770 780 KIAA14 EKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNN 760 770 780 790 800 810 790 800 810 820 830 840 KIAA14 DIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKK 820 830 840 850 860 870 850 860 870 KIAA14 RKALATSVLDILAKNLHKEVDS-------------------------------------- :::::::::::::::::::::: gi|119 RKALATSVLDILAKNLHKEVDSSSATQGAHQEHPSWKAPQDVVVEGTVTCREMLETKEEE 880 890 900 910 920 930 880 890 900 910 920 KIAA14 -ICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYN 940 950 960 970 980 990 930 940 950 960 970 980 KIAA14 LSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVA 1000 1010 1020 1030 1040 1050 990 1000 1010 1020 1030 1040 KIAA14 GFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQ 1060 1070 1080 1090 1100 1110 1050 1060 1070 1080 1090 1100 KIAA14 PYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 PYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVA 1120 1130 1140 1150 1160 1170 1110 1120 1130 1140 1150 1160 KIAA14 LDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDH 1180 1190 1200 1210 1220 1230 1170 1180 1190 1200 1210 1220 KIAA14 IESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 IESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHI 1240 1250 1260 1270 1280 1290 1230 1240 1250 1260 1270 1280 KIAA14 VMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLP 1300 1310 1320 1330 1340 1350 1290 1300 1310 1320 1330 1340 KIAA14 VESKRYQTMERIWKKIMKNAYENRE-----VINVCSDLRMLDSLRDCNKILDLVQKGLSE ::::::::::::::::::::::::: :::::::::::::::::::::::::::::: gi|119 VESKRYQTMERIWKKIMKNAYENREASSMRVINVCSDLRMLDSLRDCNKILDLVQKGLSE 1360 1370 1380 1390 1400 1410 1350 1360 1370 1380 1390 1400 KIAA14 YLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYS 1420 1430 1440 1450 1460 1470 1410 1420 1430 1440 1450 1460 KIAA14 AEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQV 1480 1490 1500 1510 1520 1530 1470 1480 1490 1500 1510 1520 KIAA14 TIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIE 1540 1550 1560 1570 1580 1590 1530 1540 1550 1560 1570 1580 KIAA14 VHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVI 1600 1610 1620 1630 1640 1650 1590 1600 1610 1620 1630 1640 KIAA14 TPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAM 1660 1670 1680 1690 1700 1710 1650 1660 1670 1680 1690 1700 KIAA14 GKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPS :::::::::::::::::::::::::::::::::::::::::::: gi|119 GKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQR---------------- 1720 1730 1740 1750 1710 1720 1730 1740 1750 1760 KIAA14 CAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITT :::::::::::::::::::::::::::::::::::::: gi|119 ----------------------ALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITT 1760 1770 1780 1790 1770 1780 1790 1800 1810 1820 KIAA14 TFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQE 1800 1810 1820 1830 1840 1850 1830 1840 1850 1860 1870 1880 KIAA14 DLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRH 1860 1870 1880 1890 1900 1910 1890 1900 1910 1920 1930 1940 KIAA14 GLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFD 1920 1930 1940 1950 1960 1970 1950 1960 1970 1980 1990 2000 KIAA14 LLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEI 1980 1990 2000 2010 2020 2030 2010 2020 2030 2040 2050 2060 KIAA14 IKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 IKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEH 2040 2050 2060 2070 2080 2090 2070 2080 2090 2100 2110 2120 KIAA14 FKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKL 2100 2110 2120 2130 2140 2150 2130 2140 2150 2160 2170 2180 KIAA14 SRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLE 2160 2170 2180 2190 2200 2210 2190 2200 2210 2220 2230 2240 KIAA14 DAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDML 2220 2230 2240 2250 2260 2270 2250 2260 2270 2280 2290 2300 KIAA14 LTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKR 2280 2290 2300 2310 2320 2330 2310 2320 2330 2340 2350 2360 KIAA14 RKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 RKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVD 2340 2350 2360 2370 2380 2390 2370 2380 2390 2400 2410 2420 KIAA14 INFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 INFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYR 2400 2410 2420 2430 2440 2450 2430 2440 2450 2460 2470 2480 KIAA14 ERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPA 2460 2470 2480 2490 2500 2510 2490 2500 2510 2520 2530 2540 KIAA14 KVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYG 2520 2530 2540 2550 2560 2570 2550 2560 2570 2580 2590 2600 KIAA14 DFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLR 2580 2590 2600 2610 2620 2630 2610 2620 2630 2640 2650 2660 KIAA14 QALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQN 2640 2650 2660 2670 2680 2690 2670 2680 2690 2700 2710 2720 KIAA14 LPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKA 2700 2710 2720 2730 2740 2750 2730 2740 2750 2760 2770 2780 KIAA14 NLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATV 2760 2770 2780 2790 2800 2810 2790 2800 2810 2820 2830 2840 KIAA14 FLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSI 2820 2830 2840 2850 2860 2870 2850 2860 2870 2880 2890 2900 KIAA14 LIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKV 2880 2890 2900 2910 2920 2930 2910 2920 2930 2940 2950 2960 KIAA14 DTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVT 2940 2950 2960 2970 2980 2990 2970 2980 2990 3000 3010 3020 KIAA14 EVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESL 3000 3010 3020 3030 3040 3050 3030 3040 3050 3060 3070 3080 KIAA14 FKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPK 3060 3070 3080 3090 3100 3110 3090 3100 3110 3120 3130 3140 KIAA14 RQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 RQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRL 3120 3130 3140 3150 3160 3170 3150 3160 3170 3180 3190 3200 KIAA14 GRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSW 3180 3190 3200 3210 3220 3230 3210 3220 3230 3240 3250 3260 KIAA14 VKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDP 3240 3250 3260 3270 3280 3290 3270 3280 3290 3300 3310 3320 KIAA14 QSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLK 3300 3310 3320 3330 3340 3350 3330 3340 3350 3360 3370 3380 KIAA14 QTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQ 3360 3370 3380 3390 3400 3410 3390 3400 3410 3420 3430 3440 KIAA14 LLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLE 3420 3430 3440 3450 3460 3470 3450 3460 3470 3480 3490 3500 KIAA14 ASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEW 3480 3490 3500 3510 3520 3530 3510 3520 3530 3540 3550 3560 KIAA14 FLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMN 3540 3550 3560 3570 3580 3590 3570 3580 3590 3600 3610 3620 KIAA14 EGKINQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EGKINQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSE 3600 3610 3620 3630 3640 3650 3630 3640 3650 3660 3670 3680 KIAA14 FRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQ 3660 3670 3680 3690 3700 3710 3690 3700 3710 3720 3730 3740 KIAA14 TANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAM ..:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ATNLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAM 3720 3730 3740 3750 3760 3770 3750 3760 3770 3780 3790 3800 KIAA14 MRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 MRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQ 3780 3790 3800 3810 3820 3830 3810 3820 3830 3840 3850 3860 KIAA14 NGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGP 3840 3850 3860 3870 3880 3890 3870 3880 3890 3900 3910 3920 KIAA14 LGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMN 3900 3910 3920 3930 3940 3950 3930 3940 3950 3960 3970 3980 KIAA14 ILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANIT 3960 3970 3980 3990 4000 4010 3990 4000 4010 4020 4030 4040 KIAA14 FAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLY 4020 4030 4040 4050 4060 4070 4050 4060 4070 4080 4090 4100 KIAA14 EESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWS 4080 4090 4100 4110 4120 4130 4110 4120 4130 4140 4150 4160 KIAA14 AKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARKFV 4140 4150 4160 4170 4180 4190 4170 4180 4190 4200 4210 4220 KIAA14 ISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMA 4200 4210 4220 4230 4240 4250 4230 4240 4250 4260 4270 4280 KIAA14 VIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRG 4260 4270 4280 4290 4300 4310 4290 KIAA14 VALICALDY ::::::::: gi|119 VALICALDY 4320 >>gi|109039223|ref|XP_001085984.1| PREDICTED: similar to (4313 aa) initn: 27676 init1: 15531 opt: 20128 Z-score: 19785.7 bits: 3676.7 E(): 0 Smith-Waterman score: 27641; 96.985% identity (98.878% similar) in 4278 aa overlap (18-4293:48-4313) 10 20 30 40 KIAA14 NHSLDSGKVAPPSGLEGSFGWGISLRSSMEQPNSKGYSLGRTPQGPE ::::::::::::::::::: : :::::::: gi|109 TLQLGETAMTITCSHIPCDVTNPQLKPTVQSFGWGISLRSSMEQPNSKGCSPGRTPQGPE 20 30 40 50 60 70 50 60 70 80 90 100 KIAA14 CSSAPAVQVGTHRGLEYNPGKILPGSDYGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRK ::.::.::.:::::::::: ::::::::::::::::::::::: :::::::::::::::: gi|109 CSGAPGVQAGTHRGLEYNPEKILPGSDYGLGNPPALDPKLPHLSLPPAPPTLSDLGQPRK 80 90 100 110 120 130 110 120 130 140 150 160 KIAA14 SPLTGTDKKYPLMKQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSF :::::.:::::::::::.::::::::::::::::::::::::::::::::::::::::.: gi|109 SPLTGNDKKYPLMKQRGYYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGTF 140 150 160 170 180 190 170 180 190 200 210 220 KIAA14 EVPEDFQERMEQQCIGSTTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQY :::::::::.:::::::::::::::::::::::::.::::::::::.::::::::::::: gi|109 EVPEDFQERVEQQCIGSTTRLLAQTDFPLQAYEPKVQVPFQVLPGQRPRKIEIERRKQQY 200 210 220 230 240 250 230 240 250 260 270 280 KIAA14 LSLDIEQLLFSQGIDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLKVFDNEDFDCRTPR ::::::::::::::::::::::::: ::::::::::::.::::::::::::::::::::: gi|109 LSLDIEQLLFSQGIDSNKLMPRHLDPQHPQTIEQGHDPLFPIYLPLKVFDNEDFDCRTPR 260 270 280 290 300 310 290 300 310 320 330 340 KIAA14 EWINMGLEPGSLDRKPVPGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLV :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: gi|109 EWINMGLEPGSLDRKPVPGKALLPTDDFLGHEDPKSQKLKYEWCEVGVLDYDEEKKLYLV 320 330 340 350 360 370 350 360 370 380 390 400 KIAA14 HKTDEKGLVRDEMGRPILNAGVTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQAN ::::::::::::::::::::::: ::::::::::::::::::::::::::.::::::::: gi|109 HKTDEKGLVRDEMGRPILNAGVTPEGRPPLQVCQYWVPRIQLLFCAEDPCVFAQRVVQAN 380 390 400 410 420 430 410 420 430 440 450 460 KIAA14 ALRKNTEALLLYNLYVDCMPSDGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAR ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: gi|109 ALRKNTEALLLYNLYVDCMPSDGQRVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAR 440 450 460 470 480 490 470 480 490 500 510 520 KIAA14 EVSLDYERSMNKINFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFT :::::::::::::::::.:::::.:::::::::::::::::.:::::::::: ::::::: gi|109 EVSLDYERSMNKINFDHIVSSKPQTFSYVTLPKKEEEQVPEQGLVSVPKYHFREQKEDFT 500 510 520 530 540 550 530 540 550 560 570 580 KIAA14 FVSLLTRPEVITALSKVRAECNKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKD :::::::::::::::::::::::::.::::::.:::::.::::::::::::::::::::: gi|109 FVSLLTRPEVITALSKVRAECNKVTTMSLFHSNLSKYSRLEEFEQIQSQTFSQVQMFLKD 560 570 580 590 600 610 590 600 610 620 630 640 KIAA14 SWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSL ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: gi|109 SWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMEMVKYMLQDTLRFLVQDSL 620 630 640 650 660 670 650 660 670 680 690 700 KIAA14 ASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQF :::::::::.:::::::::::::::::::::::::::::::.:::::::::::::::::: gi|109 ASFSQFISDACCSVLNCTDDMVWGDDLINSPYRPRKNPLFIVDLVLDSSGVHYSTPLEQF 680 690 700 710 720 730 710 720 730 740 750 760 KIAA14 EASLLNLFDKGILATHAVPQL--EKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAV :.::::::..:.:: :.:. .::::::::::::::::::::::::::::::::::: gi|109 ETSLLNLFSQGLLALSALPHAFPPQLVMEDIFISGDPLLESVGLHEPLVEELRATIASAV 740 750 760 770 780 790 770 780 790 800 810 820 KIAA14 SKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSL ::::::::::::::::::::::::::::::.:::::::::::::::::::.::::::::: gi|109 SKAMIPLQAYAKEYRKYLELNNNDIASFLKAYQTQGLLAQEVREVVLTHLQEKEILDSSL 800 810 820 830 840 850 830 840 850 860 870 880 KIAA14 PSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEK ::::::::::::::::::::::::::::::.::::::::::::::::.:::::::::::: gi|109 PSSIIIGPFYINTDNVKQSLSKKRKALATSMLDILAKNLHKEVDSICDEFRSISRKIYEK 860 870 880 890 900 910 890 900 910 920 930 940 KIAA14 PNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 PNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWP 920 930 940 950 960 970 950 960 970 980 990 1000 KIAA14 SKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 SKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIAN 980 990 1000 1010 1020 1030 1010 1020 1030 1040 1050 1060 KIAA14 EVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWS ::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::: gi|109 EVRRVKKQLKDCQQLAMLYNNRERIFGLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWS 1040 1050 1060 1070 1080 1090 1070 1080 1090 1100 1110 1120 KIAA14 ESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 ESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPL 1100 1110 1120 1130 1140 1150 1130 1140 1150 1160 1170 1180 KIAA14 IQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYA :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 IQGLRNPGMRNRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYA 1160 1170 1180 1190 1200 1210 1190 1200 1210 1220 1230 1240 KIAA14 IEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFE ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: gi|109 IEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQSMSFSPYKKPFE 1220 1230 1240 1250 1260 1270 1250 1260 1270 1280 1290 1300 KIAA14 QRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKI ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: gi|109 QRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINRQLPVESKRYQTMERIWKKI 1280 1290 1300 1310 1320 1330 1310 1320 1330 1340 1350 1360 KIAA14 MKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 MKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELL 1340 1350 1360 1370 1380 1390 1370 1380 1390 1400 1410 1420 KIAA14 EILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSSNVEDW ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: gi|109 EILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYSAEGEEVQLSFSIYPSSNVEDW 1400 1410 1420 1430 1440 1450 1430 1440 1450 1460 1470 1480 KIAA14 LREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGN :.:::::::::::::::.:::::::: :::::::::::::::::::::::::::::::.. gi|109 LQEVERSMKASVHDIIERAIRAYPTMLRTQWVLNWPGQVTIAGCQTYWTMEVAEALEASD 1460 1470 1480 1490 1500 1510 1490 1500 1510 1520 1530 1540 KIAA14 LRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDF :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 LRSRLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDF 1520 1530 1540 1550 1560 1570 1550 1560 1570 1580 1590 1600 KIAA14 QWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGG .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 EWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGG 1580 1590 1600 1610 1620 1630 1610 1620 1630 1640 1650 1660 KIAA14 APAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 APAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNR 1640 1650 1660 1670 1680 1690 1670 1680 1690 1700 1710 1720 KIAA14 IDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 IDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNL 1700 1710 1720 1730 1740 1750 1730 1740 1750 1760 1770 1780 KIAA14 KALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRA :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: gi|109 KALFRPVAMMVPDYAMIAEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRA 1760 1770 1780 1790 1800 1810 1790 1800 1810 1820 1830 1840 KIAA14 VKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 VKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDT 1820 1830 1840 1850 1860 1870 1850 1860 1870 1880 1890 1900 KIAA14 DYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAA ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: gi|109 DYGILDEAIREACRKSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAA 1880 1890 1900 1910 1920 1930 1910 1920 1930 1940 1950 1960 KIAA14 AMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAIT ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::. gi|109 AMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSLIRAGAIA 1940 1950 1960 1970 1980 1990 1970 1980 1990 2000 2010 2020 KIAA14 SDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASP ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: gi|109 SDTNKKWYMFDGPVDAVWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASP 2000 2010 2020 2030 2040 2050 2030 2040 2050 2060 2070 2080 KIAA14 ATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVK ::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::: gi|109 ATVSRCGMVYLEPSILGLMPFIECWLKKLPPLLKPYEEHFKALFVSFLEESISFVRSSVK 2060 2070 2080 2090 2100 2110 2090 2100 2110 2120 2130 2140 KIAA14 EVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGA :::::::::::::::::::::::::::::::::::::::::..:::::::::::.::::: gi|109 EVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRVAELIEPWFIFSLVWSVGA 2120 2130 2140 2150 2160 2170 2150 2160 2170 2180 2190 2200 KIAA14 TGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVA ::::.:::::::::::::::::::::::::::::::::::::::::::.::::::::::: gi|109 TGDSNGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDNEDEEEEYKQVA 2180 2190 2200 2210 2220 2230 2210 2220 2230 2240 2250 2260 KIAA14 WVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 WVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTI 2240 2250 2260 2270 2280 2290 2270 2280 2290 2300 2310 2320 KIAA14 SDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLN ::::::::::.:.::::::::::::::::: :::::::::::::::::::.::::::::: gi|109 SDKLLKNLALEYVSHFLTFSARTSANQTQDVIDSKLDKRRKGVFGPPLGRSFIFFIDDLN 2300 2310 2320 2330 2340 2350 2330 2340 2350 2360 2370 2380 KIAA14 MPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: gi|109 MPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTITPRL 2360 2370 2380 2390 2400 2410 2390 2400 2410 2420 2430 2440 KIAA14 MRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATI ::::::::::::::::::::::::::::..:::::::::: ::::::::::::::::::: gi|109 MRHFNYLSFAEMDEVSKKRIFSTILGNWMNGLLGEKSYREPVPGAPHIAHFTEPLVEATI 2420 2430 2440 2450 2460 2470 2450 2460 2470 2480 2490 2500 KIAA14 MVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 MVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFR 2480 2490 2500 2510 2520 2530 2510 2520 2530 2540 2550 2560 KIAA14 DRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYGDFMSPGSDVKSYELITSESKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 DRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYGDFMSPGSDVKSYELITSESKM 2540 2550 2560 2570 2580 2590 2570 2580 2590 2600 2610 2620 KIAA14 MQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 MQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTR 2600 2610 2620 2630 2640 2650 2630 2640 2650 2660 2670 2680 KIAA14 LASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDI ::::::::::::::::::::: :::.:::::::::::::::::::::::::::::::::: gi|109 LASHMAEYECFQIELSKNYGMPEWREDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDI 2660 2670 2680 2690 2700 2710 2690 2700 2710 2720 2730 2740 KIAA14 NNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMS ::::::::::::::.:::::::::::::.::::::::::::::::::::::::::::::: gi|109 NNVLNSGDIPNLYTVDEQDQIVSTMRPYVQEQGLQPTKANLMAAYTGRVRSNIHMVLCMS 2720 2730 2740 2750 2760 2770 2750 2760 2770 2780 2790 2800 KIAA14 PIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQV ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: gi|109 PIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATMFLNEIPELESSQEEIQGLIQV 2780 2790 2800 2810 2820 2830 2810 2820 2830 2840 2850 2860 KIAA14 CVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 CVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLD 2840 2850 2860 2870 2880 2890 2870 2880 2890 2900 2910 2920 KIAA14 KLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 KLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANE 2900 2910 2920 2930 2940 2950 2930 2940 2950 2960 2970 2980 KIAA14 KAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 KAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCI 2960 2970 2980 2990 3000 3010 2990 3000 3010 3020 3030 3040 KIAA14 MKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYID :::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: gi|109 MKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGRFLESLFKFDKDNIGDVVIKAIQPYID 3020 3030 3040 3050 3060 3070 3050 3060 3070 3080 3090 3100 KIAA14 NEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEA :::::::.::::::::::::::::::::::::::::::::::: :::::::::::::::: gi|109 NEEFQPAAIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALREAQDDLGVTQRILDEA 3080 3090 3100 3110 3120 3130 3110 3120 3130 3140 3150 3160 KIAA14 KQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETV :::::::::::::. : . : .:::::::::::::::: gi|109 KQRLREVEDGIATIPRP------------LAQPPRAHATGLPLQLINGLSDEKVRWQETV 3140 3150 3160 3170 3180 3170 3180 3190 3200 3210 3220 KIAA14 ENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 ENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTL 3190 3200 3210 3220 3230 3240 3230 3240 3250 3260 3270 3280 KIAA14 GNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 GNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFK 3250 3260 3270 3280 3290 3300 3290 3300 3310 3320 3330 3340 KIAA14 LSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 LSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYH 3310 3320 3330 3340 3350 3360 3350 3360 3370 3380 3390 3400 KIAA14 EDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 EDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLI 3370 3380 3390 3400 3410 3420 3410 3420 3430 3440 3450 3460 KIAA14 ISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 ISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEK 3430 3440 3450 3460 3470 3480 3470 3480 3490 3500 3510 3520 KIAA14 DIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKR :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::: gi|109 DIDLTRMEYIPVAVRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKR 3490 3500 3510 3520 3530 3540 3530 3540 3550 3560 3570 3580 KIAA14 ISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIM ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::.:: gi|109 ISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWHYLLSGGSIQIM 3550 3560 3570 3580 3590 3600 3590 3600 3610 3620 3630 3640 KIAA14 TENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQ ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::. gi|109 TENPAPDWLSDRAWRDILALSNLPNFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDK 3610 3620 3630 3640 3650 3660 3650 3660 3670 3680 3690 3700 KIAA14 YLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 YLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVL 3670 3680 3690 3700 3710 3720 3710 3720 3730 3740 3750 3760 KIAA14 SPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 SPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPS 3730 3740 3750 3760 3770 3780 3770 3780 3790 3800 3810 3820 KIAA14 WMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSY ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: gi|109 WMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVKANLLKSY 3790 3800 3810 3820 3830 3840 3830 3840 3850 3860 3870 3880 KIAA14 SSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQL .::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 NSLSEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQL 3850 3860 3870 3880 3890 3900 3890 3900 3910 3920 3930 3940 KIAA14 KMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 KMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASG 3910 3920 3930 3940 3950 3960 3950 3960 3970 3980 3990 4000 KIAA14 IYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 IYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSS 3970 3980 3990 4000 4010 4020 4010 4020 4030 4040 4050 4060 KIAA14 SAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQV :::..::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 SAGGRGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQV 4030 4040 4050 4060 4070 4080 4070 4080 4090 4100 4110 4120 KIAA14 ITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRL :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: gi|109 ITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPQLWSAKAYPSLKPLSSWVMDLLQRL 4090 4100 4110 4120 4130 4140 4130 4140 4150 4160 4170 4180 KIAA14 DFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELT :::::::: :::::::::::::::::::::::::::::::::::::::::::.:.::::: gi|109 DFLQAWIQGGIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMLETPSELT 4150 4160 4170 4180 4190 4200 4190 4200 4210 4220 4230 4240 KIAA14 QRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCP ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: gi|109 QRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRMAQDQDFYLCP 4210 4220 4230 4240 4250 4260 4250 4260 4270 4280 4290 KIAA14 IYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALICALDY :::::::::::::::::::::::::::::::::::::::::::::::: gi|109 IYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALICALDY 4270 4280 4290 4300 4310 >>gi|119585623|gb|EAW65219.1| dynein, axonemal, heavy po (4334 aa) initn: 22018 init1: 12634 opt: 16003 Z-score: 15727.8 bits: 2925.9 E(): 0 Smith-Waterman score: 27570; 95.743% identity (95.743% similar) in 4393 aa overlap (29-4293:1-4334) 10 20 30 40 50 60 KIAA14 NHSLDSGKVAPPSGLEGSFGWGISLRSSMEQPNSKGYSLGRTPQGPECSSAPAVQVGTHR :::::::::::::::::::::::::::::::: gi|119 MEQPNSKGYSLGRTPQGPECSSAPAVQVGTHR 10 20 30 70 80 90 100 110 120 KIAA14 GLEYNPGKILPGSDYGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GLEYNPGKILPGSDYGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDKKYPLM 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQ 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 CIGSTTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQLLFSQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 CIGSTTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQLLFSQG 160 170 180 190 200 210 250 260 270 KIAA14 IDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLK-------------------------- :::::::::::::::::::::::::::::::::: gi|119 IDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLKPVCLASASVPPMGNLDAAQLDCGVSS 220 230 240 250 260 270 280 290 300 310 KIAA14 -------VFDNEDFDCRTPREWINMGLEPGSLDRKPVPGKALLPTDDFLGH--------- :::::::::::::::::::::::::::::::::::::::::::: gi|119 LTSARLRVFDNEDFDCRTPREWINMGLEPGSLDRKPVPGKALLPTDDFLGHGLPQRLWRL 280 290 300 310 320 330 320 330 340 350 360 KIAA14 ----------EDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRPILNAG :::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SHFLLWKAVPEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRPILNAG 340 350 360 370 380 390 370 380 390 400 410 420 KIAA14 VTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEALLLYNLYVDCMPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEALLLYNLYVDCMPS 400 410 420 430 440 450 430 440 450 460 470 480 KIAA14 DGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDYERSMNKINFDHVVSS 460 470 480 490 500 510 490 500 510 520 530 540 KIAA14 KPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAEC 520 530 540 550 560 570 550 560 570 580 590 600 KIAA14 NKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGW 580 590 600 610 620 630 610 620 630 640 650 660 KIAA14 YNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDM 640 650 660 670 680 690 670 680 690 700 710 720 KIAA14 VWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQL 700 710 720 730 740 750 730 740 750 760 770 780 KIAA14 EKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNN 760 770 780 790 800 810 790 800 810 820 830 840 KIAA14 DIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKK 820 830 840 850 860 870 850 860 870 KIAA14 RKALATSVLDILAKNLHKEVDS-------------------------------------- :::::::::::::::::::::: gi|119 RKALATSVLDILAKNLHKEVDSSSATQGAHQEHPSWKAPQDVVVEGTVTCREMLETKEEE 880 890 900 910 920 930 880 890 900 910 920 KIAA14 -ICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYN 940 950 960 970 980 990 930 940 950 960 970 980 KIAA14 LSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVA 1000 1010 1020 1030 1040 1050 990 1000 1010 1020 1030 1040 KIAA14 GFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQ 1060 1070 1080 1090 1100 1110 1050 1060 1070 1080 1090 1100 KIAA14 PYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 PYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVA 1120 1130 1140 1150 1160 1170 1110 1120 1130 1140 1150 1160 KIAA14 LDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDH 1180 1190 1200 1210 1220 1230 1170 1180 1190 1200 1210 1220 KIAA14 IESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 IESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHI 1240 1250 1260 1270 1280 1290 1230 1240 1250 1260 1270 1280 KIAA14 VMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLP 1300 1310 1320 1330 1340 1350 1290 1300 1310 1320 1330 1340 KIAA14 VESKRYQTMERIWKKIMKNAYENRE-----VINVCSDLRMLDSLRDCNKILDLVQKGLSE ::::::::::::::::::::::::: :::::::::::::::::::::::::::::: gi|119 VESKRYQTMERIWKKIMKNAYENREASSMRVINVCSDLRMLDSLRDCNKILDLVQKGLSE 1360 1370 1380 1390 1400 1410 1350 1360 1370 1380 1390 1400 KIAA14 YLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYS 1420 1430 1440 1450 1460 1470 1410 1420 1430 1440 1450 1460 KIAA14 AEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQV 1480 1490 1500 1510 1520 1530 1470 1480 1490 1500 1510 1520 KIAA14 TIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIE 1540 1550 1560 1570 1580 1590 1530 1540 1550 1560 1570 1580 KIAA14 VHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVI 1600 1610 1620 1630 1640 1650 1590 1600 1610 1620 1630 1640 KIAA14 TPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAM 1660 1670 1680 1690 1700 1710 1650 1660 1670 1680 1690 1700 KIAA14 GKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPS :::::::::::::::::::::::::::::::::::::::::::: gi|119 GKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQR---------------- 1720 1730 1740 1750 1710 1720 1730 1740 1750 1760 KIAA14 CAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITT :::::::::::::::::::::::::::::::::::::: gi|119 ----------------------ALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITT 1760 1770 1780 1790 1770 1780 1790 1800 1810 1820 KIAA14 TFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQE 1800 1810 1820 1830 1840 1850 1830 1840 1850 1860 1870 1880 KIAA14 DLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRH 1860 1870 1880 1890 1900 1910 1890 1900 1910 1920 1930 1940 KIAA14 GLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFD 1920 1930 1940 1950 1960 1970 1950 1960 1970 1980 1990 2000 KIAA14 LLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEI 1980 1990 2000 2010 2020 2030 2010 2020 2030 2040 2050 2060 KIAA14 IKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 IKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEH 2040 2050 2060 2070 2080 2090 2070 2080 2090 2100 2110 2120 KIAA14 FKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKL 2100 2110 2120 2130 2140 2150 2130 2140 2150 2160 2170 2180 KIAA14 SRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLE 2160 2170 2180 2190 2200 2210 2190 2200 2210 2220 2230 2240 KIAA14 DAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDML 2220 2230 2240 2250 2260 2270 2250 2260 2270 2280 2290 2300 KIAA14 LTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKR 2280 2290 2300 2310 2320 2330 2310 2320 2330 2340 2350 2360 KIAA14 RKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 RKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVD 2340 2350 2360 2370 2380 2390 2370 2380 2390 2400 2410 2420 KIAA14 INFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 INFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYR 2400 2410 2420 2430 2440 2450 2430 2440 2450 2460 2470 2480 KIAA14 ERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPA 2460 2470 2480 2490 2500 2510 2490 2500 2510 2520 2530 2540 KIAA14 KVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYG 2520 2530 2540 2550 2560 2570 2550 2560 2570 2580 2590 2600 KIAA14 DFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLR 2580 2590 2600 2610 2620 2630 2610 2620 2630 2640 2650 2660 KIAA14 QALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQN 2640 2650 2660 2670 2680 2690 2670 2680 2690 2700 2710 2720 KIAA14 LPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKA 2700 2710 2720 2730 2740 2750 2730 2740 2750 2760 2770 2780 KIAA14 NLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATV 2760 2770 2780 2790 2800 2810 2790 2800 2810 2820 2830 2840 KIAA14 FLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSI 2820 2830 2840 2850 2860 2870 2850 2860 2870 2880 2890 2900 KIAA14 LIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKV 2880 2890 2900 2910 2920 2930 2910 2920 2930 2940 2950 2960 KIAA14 DTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVT 2940 2950 2960 2970 2980 2990 2970 2980 2990 3000 3010 3020 KIAA14 EVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESL 3000 3010 3020 3030 3040 3050 3030 3040 3050 3060 3070 3080 KIAA14 FKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPK 3060 3070 3080 3090 3100 3110 3090 3100 3110 3120 3130 3140 KIAA14 RQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 RQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRL 3120 3130 3140 3150 3160 3170 3150 3160 3170 3180 3190 3200 KIAA14 GRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSW 3180 3190 3200 3210 3220 3230 3210 3220 3230 3240 3250 3260 KIAA14 VKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDP 3240 3250 3260 3270 3280 3290 3270 3280 3290 3300 3310 3320 KIAA14 QSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLK 3300 3310 3320 3330 3340 3350 3330 3340 3350 3360 3370 3380 KIAA14 QTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQ 3360 3370 3380 3390 3400 3410 3390 3400 3410 3420 3430 3440 KIAA14 LLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLE 3420 3430 3440 3450 3460 3470 3450 3460 3470 3480 3490 3500 KIAA14 ASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEW 3480 3490 3500 3510 3520 3530 3510 3520 3530 3540 3550 3560 KIAA14 FLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMN 3540 3550 3560 3570 3580 3590 3570 3580 3590 3600 3610 3620 KIAA14 EGKINQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EGKINQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSE 3600 3610 3620 3630 3640 3650 3630 3640 3650 KIAA14 FRVIFDSLEPHR--------------------------------EPLPGIWDQYLDQFQK :::::::::::: :::::::::::::::: gi|119 FRVIFDSLEPHRPLSPAVRLAESLGPPTSFQQAGSQGGVGHCCREPLPGIWDQYLDQFQK 3660 3670 3680 3690 3700 3710 3660 3670 3680 3690 3700 3710 KIAA14 LLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPA ::::::::::: :::::::::::::::::::::::::::: gi|119 LLVLRCLRGDK---------------------TANLSVVFKDSNSTTPLIFVLSPGTDPA 3720 3730 3740 3750 3720 3730 3740 3750 3760 3770 KIAA14 ADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALER 3760 3770 3780 3790 3800 3810 3780 3790 3800 3810 3820 3830 KIAA14 LIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDF 3820 3830 3840 3850 3860 3870 3840 3850 3860 3870 3880 3890 KIAA14 LNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEY 3880 3890 3900 3910 3920 3930 3900 3910 3920 3930 3940 3950 KIAA14 DDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPP 3940 3950 3960 3970 3980 3990 3960 3970 3980 3990 4000 4010 KIAA14 TYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGR 4000 4010 4020 4030 4040 4050 4020 4030 4040 4050 4060 4070 KIAA14 EEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQD 4060 4070 4080 4090 4100 4110 4080 4090 4100 4110 4120 4130 KIAA14 LLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWI 4120 4130 4140 4150 4160 4170 4140 4150 4160 4170 4180 4190 KIAA14 QDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGC 4180 4190 4200 4210 4220 4230 4200 4210 4220 4230 4240 4250 KIAA14 YIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTR 4240 4250 4260 4270 4280 4290 4260 4270 4280 4290 KIAA14 AGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALICALDY ::::::::::::::::::::::::::::::::::::::::: gi|119 AGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALICALDY 4300 4310 4320 4330 >>gi|73985528|ref|XP_533802.2| PREDICTED: similar to dyn (4259 aa) initn: 24019 init1: 12368 opt: 14387 Z-score: 14138.2 bits: 2631.7 E(): 0 Smith-Waterman score: 25892; 90.384% identity (97.005% similar) in 4274 aa overlap (29-4293:1-4259) 10 20 30 40 50 KIAA14 NHSLDSGKVAPPSGLEGSFGWGISLRSSMEQPNSKGYSLGRTPQGPECSSAPAVQVG--- ::::: .:.: :::::.::::. :. : gi|739 MEQPNREGHSPGRTPQSPECSGIPGGQECSLK 10 20 30 60 70 80 90 100 110 KIAA14 -THRGLEYNPGKILPGSDYGLGNP-PALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDK :: ::.: .:: : :.: .: :. ::. : :::: .:::::::::::: :::.::: gi|739 RTHADLEHNLERILLGPDFGSEKPLPSADPN-P-LPLPLSPPTLSDLGQPRKLPLTATDK 40 50 60 70 80 90 120 130 140 150 160 170 KIAA14 KYPLMKQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQE .:::::::::::::::::.:::.:::::::.:.:.::::::::::::.: .::.::::.: gi|739 QYPLMKQRGFYSDILSPGSLDQIGEVCRGPHMNQDLLRQADLDKFTPKVKTFEIPEDFEE 100 110 120 130 140 150 180 190 200 210 220 230 KIAA14 RMEQQCIGSTTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLSLDIEQL .::. :::::.::..::::::::::: :::: ::::: ::::::::::. ::::::::: gi|739 SLEQEHIGSTTQLLTHTDFPLQAYEPKAQVPFLVLPGQCPRKIEIERRKRLYLSLDIEQL 160 170 180 190 200 210 240 250 260 270 280 290 KIAA14 LFSQGIDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLKVFDNEDFDCRTPREWINMGLE : ..::::::::::: : :.:::::::.::::: ::::::::::.:::::: :::::::: gi|739 LAQEGIDSNKLMPRHPDPQNPQTIEQGNDPIFPTYLPLKVFDNEEFDCRTPSEWINMGLE 220 230 240 250 260 270 300 310 320 330 340 350 KIAA14 PGSLDRKPVPGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGL ::: :::::::::::::::.:::::::::::::.:: :::::::.::::::::::...:: gi|739 PGSQDRKPVPGKALLPTDDILGHEDPKSQKLKYEWCSVGVLDYDKEKKLYLVHKTEQSGL 280 290 300 310 320 330 360 370 380 390 400 410 KIAA14 VRDEMGRPILNAGVTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANALRKNTEA ::::::.::::.:.:.:::::: .::::::::::::::::: .:.::::::::::::::: gi|739 VRDEMGKPILNGGITAEGRPPLLTCQYWVPRIQLLFCAEDPRVFTQRVVQANALRKNTEA 340 350 360 370 380 390 420 430 440 450 460 470 KIAA14 LLLYNLYVDCMPSDGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDYER :::::::::::::.:...::::::.::::::.:::::::: ::::::.::..::.::::: gi|739 LLLYNLYVDCMPSEGRQLISEQSLNKIKQWAMSTPRMRKGSSVLEHLNSLSKEVNLDYER 400 410 420 430 440 450 480 490 500 510 520 530 KIAA14 SMNKINFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRP ::::::::..:::::.:::::::::::::.::..:::::::: : ::::::::::::::: gi|739 SMNKINFDQIVSSKPDTFSYVTLPKKEEEKVPRQGLVSVPKYPFQEQKEDFTFVSLLTRP 460 470 480 490 500 510 540 550 560 570 580 590 KIAA14 EVITALSKVRAECNKVTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKV ::::::::::::::::::::::::.:::::.:::::::::::::::::::::::::.::: gi|739 EVITALSKVRAECNKVTAMSLFHSNLSKYSRLEEFEQIQSQTFSQVQMFLKDSWISTLKV 520 530 540 550 560 570 600 610 620 630 640 650 KIAA14 AMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFIS :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: gi|739 AMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMELLKYMLQDTLRFLVQDSLASFSQFIS 580 590 600 610 620 630 660 670 680 690 700 710 KIAA14 DTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLF :.::.::.: ::::: .::::::::::::::::.:::::.::::::::::.::.:::::: gi|739 DACCNVLDCPDDMVWVEDLINSPYRPRKNPLFIVDLVLDGSGVHYSTPLEHFETSLLNLF 640 650 660 670 680 690 720 730 740 750 760 770 KIAA14 DKGILATHAVPQLEKLVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAY :::::::::::::::::::::::::::::::::::::::::::: :..:: ::::::::: gi|739 DKGILATHAVPQLEKLVMEDIFISGDPLLESVGLHEPLVEELRAIITNAVRKAMIPLQAY 700 710 720 730 740 750 780 790 800 810 820 830 KIAA14 AKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFY :.::.:::::::::::.:::.:: . :.:::::::::::::::::::::::.:::::: gi|739 AREYQKYLELNNNDIATFLKAYQMHCPSAEEVREVVLTHLREKEILDSSLPSSVIIGPFY 760 770 780 790 800 810 840 850 860 870 880 890 KIAA14 INTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAEL :: :::::::::: ::::::.:::::::::::::.::::::::::::::::::::::::: gi|739 INIDNVKQSLSKKCKALATSMLDILAKNLHKEVDDICEEFRSISRKIYEKPNSIEELAEL 820 830 840 850 860 870 900 910 920 930 940 950 KIAA14 REWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELV :::::::::.::::::::::::.::.::::::::::..:::::: :::::::::::::.: gi|739 REWMKGIPEKLVGLEERIVKVMNDYKVMDEFLYNLSTEDFNDKWAASNWPSKILGQIEMV 880 890 900 910 920 930 960 970 980 990 1000 1010 KIAA14 QQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLK .:::.::::::.::::::::::::::::::::::::: ::::.::::::::::::::::: gi|739 RQQHIEDEEKFHKIQIMDQNNFQEKLEGLQLVVAGFSTHVEIARAHEIANEVRRVKKQLK 940 950 960 970 980 990 1020 1030 1040 1050 1060 1070 KIAA14 DCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSA ::::::::::::::::.:::::::::.::::::::::::::::::::::::::::::::: gi|739 DCQQLAMLYNNRERIFGLPITNYDKLTRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSA 1000 1010 1020 1030 1040 1050 1080 1090 1100 1110 1120 1130 KIAA14 IDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMR ::::::::::.:.:::::::::::::.::::.:::::::::::::::::::::::::::: gi|739 IDAEQLEKNVIESFKTMHKCVKQFKDIPACQDVALDIRARIEEFKPYIPLIQGLRNPGMR 1060 1070 1080 1090 1100 1110 1140 1150 1160 1170 1180 1190 KIAA14 IRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEK ::::.:::.:::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 NRHWEVLSNEININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEK 1120 1130 1140 1150 1160 1170 1200 1210 1220 1230 1240 1250 KIAA14 EWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKL ::::::::::::: :.::::::::::::::::::::::.::::::::::::::::::::: gi|739 EWSTILFNVLPYKETETYILKSPDEASQLLDDHIVMTQSMSFSPYKKPFEQRINSWENKL 1180 1190 1200 1210 1220 1230 1260 1270 1280 1290 1300 1310 KIAA14 KLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREV :::::::::::::::.::::::::::::::.::::::::::::::::.:::::::::::: gi|739 KLTQEVLEEWLNCQRAWLYLEPIFSSEDINRQLPVESKRYQTMERIWRKIMKNAYENREV 1240 1250 1260 1270 1280 1290 1320 1330 1340 1350 1360 1370 KIAA14 INVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPT :::::: :.:::::::::.::.:::::::::::::.:::::::::::::::::::::::: gi|739 INVCSDQRLLDSLRDCNKLLDMVQKGLSEYLETKRGAFPRFYFLSDDELLEILSQTKDPT 1300 1310 1320 1330 1340 1350 1380 1390 1400 1410 1420 1430 KIAA14 AVQPHLRKCFENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKA ::::::::::::::::.::::: :::::::::::::: ::::::.::::::::::::::. gi|739 AVQPHLRKCFENIARLMFQEDLAITHMYSAEGEEVQLSFSIYPSNNVEDWLREVERSMKT 1360 1370 1380 1390 1400 1410 1440 1450 1460 1470 1480 1490 KIAA14 SVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLC ::.::::.::.::::::::::::.:::::::::::::::::::::: ::: .:::::: gi|739 SVRDIIERAIKAYPTMPRTQWVLKWPGQVTIAGCQTYWTMEVAEALGIGNLSNQLFPQLA 1420 1430 1440 1450 1460 1470 1500 1510 1520 1530 1540 1550 KIAA14 QQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYW :::::::::::::::::::::::::::::::::::::::::::.::::::.::::::::: gi|739 QQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENIVSVNDFEWISQLRYYW 1480 1490 1500 1510 1520 1530 1560 1570 1580 1590 1600 1610 KIAA14 TNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGK ::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 TNDDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGK 1540 1550 1560 1570 1580 1590 1620 1630 1640 1650 1660 1670 KIAA14 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVA 1600 1610 1620 1630 1640 1650 1680 1690 1700 1710 1720 1730 KIAA14 QQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 QQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMM 1660 1670 1680 1690 1700 1710 1740 1750 1760 1770 1780 1790 KIAA14 VPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGN :::::::.::::::::::::.::::::::::::::::::::::::::::::::::::::: gi|739 VPDYAMIAEISLYSFGFNEANVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGN 1720 1730 1740 1750 1760 1770 1800 1810 1820 1830 1840 1850 KIAA14 LKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIR ::::::::.:::::::::::::::::::::::::::::::::::::::::::::::.::: gi|739 LKRENPSMDEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDKAIR 1780 1790 1800 1810 1820 1830 1860 1870 1880 1890 1900 1910 KIAA14 EACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPS .::..::::::.::::::::::::::::::::::::.:::::.::::::::::::::::: gi|739 KACEKSNLKDVDGFLTKCIQLYETTVVRHGLMLVGPAGSGKSNCYRVLAAAMTSLKGQPS 1840 1850 1860 1870 1880 1890 1920 1930 1940 1950 1960 1970 KIAA14 ISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWYMF ::::.::::::::::::::::::::::::::::::::::: :.::.:::.::.::::::: gi|739 ISGGVYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFPSLIRVGAIASDSNKKWYMF 1900 1910 1920 1930 1940 1950 1980 1990 2000 2010 2020 2030 KIAA14 DGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVY ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 DGPVDAVWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVY 1960 1970 1980 1990 2000 2010 2040 2050 2060 2070 2080 2090 KIAA14 LEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNL :::::::::::.:::::.:: :.::.::.::::::.::: ::.::: :::::::::: :: gi|739 LEPSILGLMPFVECWLRRLPALFKPHEEKFKALFVGFLEGSITFVRHSVKEVIASTNSNL 2020 2030 2040 2050 2060 2070 2100 2110 2120 2130 2140 2150 KIAA14 TMSLLKLLDCFFKPFLPRE----GLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSG :::::::::::::::::.: :::::: :::::: :::::::::::::::::::::.. gi|739 TMSLLKLLDCFFKPFLPKEVQLRGLKKIPPEKLSRIPELIEPWFIFSLIWSVGATGDSAS 2080 2090 2100 2110 2120 2130 2160 2170 2180 2190 2200 2210 KIAA14 RTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMD : :::::::.::. :.::. ::::::::::::::::::.:::.:::.:: ::.::::::: gi|739 RLSFSHWLRIKMKIENLTMHFPEEGLVFDYRLEDAGISNTNDDEDEDEEGKQIAWVKWMD 2140 2150 2160 2170 2180 2190 2220 2230 2240 2250 2260 2270 KIAA14 SSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLK ::.::::.:::::::::::::::::::.:::::: :.::::::::::::::::::::::: gi|739 SSTPFTMMPDTNYCNIIVPTMDTVQMSYLLDMLLINHKPVLCIGPTGTGKTLTISDKLLK 2200 2210 2220 2230 2240 2250 2280 2290 2300 2310 2320 2330 KIAA14 NLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALET :: :.:::::::::::::::::::.::::::::::::::::::::::::::::::::::: gi|739 NLPLEYISHFLTFSARTSANQTQDLIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALET 2260 2270 2280 2290 2300 2310 2340 2350 2360 2370 2380 2390 KIAA14 YGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNY :::::::::::::::::::::::.::.:::::::::.:::::::::::..:::: ::::: gi|739 YGAQPPIELLRQWMDHGGWYDRKVIGSFKNLVDINFICAMGPPGGGRNAITPRLTRHFNY 2320 2330 2340 2350 2360 2370 2400 2410 2420 2430 2440 2450 KIAA14 LSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATI ::::::::::::.:::::::.:. ::: :::::.::::::::::.:: gi|739 LSFAEMDEVSKKHIFSTILGSWM-------------AGAPTIAHFTDPLVEATIMVYSTI 2380 2390 2400 2410 2460 2470 2480 2490 2500 2510 KIAA14 TSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNE :::::::::::::::::::::::::::::::::::::.::::::::::.:::::::::.: gi|739 TSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDKVQLLRLWYHESCRVFRDRLVSE 2420 2430 2440 2450 2460 2470 2520 2530 2540 2550 2560 2570 KIAA14 EDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYGDFMSPGSDVKSYELITSESKMMQVIEE :::.:::.::. ::.:::.: .:::::::::::::::::::::::::::.:::::::: gi|739 EDRGWFDKLLESHMERWEVAFADICPFQPILYGDFMSPGSDVKSYELITSEKKMMQVIEE 2480 2490 2500 2510 2520 2530 2580 2590 2600 2610 2620 2630 KIAA14 YIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMA :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 YMEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMA 2540 2550 2560 2570 2580 2590 2640 2650 2660 2670 2680 2690 KIAA14 EYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNS :::::::::::::::.:::.:::::::::::..::::::::::::::::::::::::::: gi|739 EYECFQIELSKNYGMTEWREDVKKVLLKAGLHSLPITFLFSDTQIKNESFLEDINNVLNS 2600 2610 2620 2630 2640 2650 2700 2710 2720 2730 2740 2750 KIAA14 GDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVF ::::::::.:::::::.::::::::::::::::::::::::::::.:::::::::::::: gi|739 GDIPNLYTSDEQDQIVNTMRPYIQEQGLQPTKANLMAAYTGRVRSHIHMVLCMSPIGEVF 2660 2670 2680 2690 2700 2710 2760 2770 2780 2790 2800 2810 KIAA14 RARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQ :::::::::::::::::::::::::::.::::.:::::::::...: :.::::::::::: gi|739 RARLRQFPSLVNCCTIDWFNEWPAEALESVATMFLNEIPELEATSEVIKGLIQVCVYIHQ 2720 2730 2740 2750 2760 2770 2820 2830 2840 2850 2860 2870 KIAA14 SVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTS ::..::.::::::.::::::::::::::.::::: :::: :::::::::::::::::::: gi|739 SVARKCVEYLAELARHNYVTPKSYLELLNIFSILTGQKKQELKTAKNRMKSGLDKLLRTS 2780 2790 2800 2810 2820 2830 2880 2890 2900 2910 2920 2930 KIAA14 EDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQ ::::::::.:: :.::::::::::.::::::::::.::.:::::::.:::::::::.::: gi|739 EDVAKMQEELEMMRPLLEEAAKDTVLTMEQIKVDTTIAQETRNSVQAEEIKANEKARKAQ 2840 2850 2860 2870 2880 2890 2940 2950 2960 2970 2980 2990 KIAA14 AIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 AIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKP 2900 2910 2920 2930 2940 2950 3000 3010 3020 3030 3040 3050 KIAA14 KKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQP :::::::::.:::::::::::::::::.::.:::::::::::..:::::::::::::::: gi|739 KKVPGEKPGSKVDDYWEPGKGLLQDPGRFLDSLFKFDKDNIGEAVIKAIQPYIDNEEFQP 2960 2970 2980 2990 3000 3010 3060 3070 3080 3090 3100 3110 KIAA14 ATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLRE :.::::::::::::::::::::::::::::::::::: :::::: ::::::.:::::::: gi|739 AAIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALREAQDDLEVTQRILEEAKQRLRE 3020 3030 3040 3050 3060 3070 3120 3130 3140 3150 3160 3170 KIAA14 VEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYM :::::.:::.:::::::::::::::::::::::::: ::::::::::::::::::::..: gi|739 VEDGITTMQTKYRECITKKEELELKCEQCEQRLGRADKLINGLSDEKVRWQETVENLEHM 3080 3090 3100 3110 3120 3130 3180 3190 3200 3210 3220 3230 KIAA14 LNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKI :.::::::::::::::::::::::::::::..:::::. :.:::::::::::::::::.: gi|739 LGNISGDVLVAAGFVAYLGPFTGQYRTVLYNQWVKQLKRHKVPHTSEPTLIGTLGNPVNI 3140 3150 3160 3170 3180 3190 3240 3250 3260 3270 3280 3290 KIAA14 RSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDF ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: gi|739 RSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQGQANKWIKNMEKDNGLDVFKLSDRDF 3200 3210 3220 3230 3240 3250 3300 3310 3320 3330 3340 3350 KIAA14 LRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 LRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMY 3260 3270 3280 3290 3300 3310 3360 3370 3380 3390 3400 3410 KIAA14 ITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKM ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: gi|739 ITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIVSNAKM 3320 3330 3340 3350 3360 3370 3420 3430 3440 3450 3460 3470 KIAA14 RQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTR :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: gi|739 RQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTERDIDLTR 3380 3390 3400 3410 3420 3430 3480 3490 3500 3510 3520 3530 KIAA14 MEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINR :::::::.:::::::::::::::::::::::::::::: ::::::::::::::::.:::: gi|739 MEYIPVAVRTQILFFCVSDLANVDPMYQYSLEWFLNIFRSGIANSERADNLKKRIANINR 3440 3450 3460 3470 3480 3490 3540 3550 3560 3570 3580 3590 KIAA14 YLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAP ::::.::::::::::::::::::::::::::::: ::.:.:::::::::::..::::::: gi|739 YLTYNLYSNVCRSLFEKHKLMFAFLLCVRIMMNEDKIDQGEWRYLLSGGSIQLMTENPAP 3500 3510 3520 3530 3540 3550 3600 3610 3620 3630 3640 3650 KIAA14 DWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQ ::::::::::::::::::.::::..::.::::::. ::::::::::::::::..:::::: gi|739 DWLSDRAWRDILALSNLPAFSSFAQDFTKHLSEFQSIFDSLEPHREPLPGIWNEYLDQFQ 3560 3570 3580 3590 3600 3610 3660 3670 3680 3690 3700 3710 KIAA14 KLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDP :::::::::::::::::::::::::::::::::..:::::::::.::::::::::::::: gi|739 KLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQATNLSVVFKDSSSTTPLIFVLSPGTDP 3620 3630 3640 3650 3660 3670 3720 3730 3740 3750 3760 3770 KIAA14 AADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALE ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: gi|739 AADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMHSSIERGKWVFFQNCHLAPSWMPALE 3680 3690 3700 3710 3720 3730 3780 3790 3800 3810 3820 3830 KIAA14 RLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGED ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::..: gi|739 RLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVKANLLKSYSSLSDD 3740 3750 3760 3770 3780 3790 3840 3850 3860 3870 3880 3890 KIAA14 FLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDE :::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::: gi|739 FLNSCHKVMEFKSLLLSLCLFHGNALERRKFGALGFNIPYEFTDGDLRICISQLKMFLDE 3800 3810 3820 3830 3840 3850 3900 3910 3920 3930 3940 3950 KIAA14 YDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQIP :.::::::::::::::::::::::::::::.::::::.:::.:: ::::::::.:::: gi|739 YEDIPYKVLKYTAGEINYGGRVTDDWDRRCVMNILEDYYNPSVLHHEHSYSASGVYHQIQ 3860 3870 3880 3890 3900 3910 3960 3970 3980 3990 4000 4010 KIAA14 PTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQG :::::.:::::::.:::::::::::::::::::::::::.::.:.:::::::::: :: : gi|739 PTYDLNGYLSYIKGLPLNDMPEIFGLHDNANITFAQNETYALFGAIIQLQPKSSSMGSLG 3920 3930 3940 3950 3960 3970 4020 4030 4040 4050 4060 4070 KIAA14 REEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQ :::.::::..:.::.:::::::: :.::::::::::::::::::::::::::::::.::. gi|739 REEVVEDVAHNVLLQVPEPINLQMVVAKYPVLYEESMNTVLVQEVIRYNRLLQVITETLR 3980 3990 4000 4010 4020 4030 4080 4090 4100 4110 4120 4130 KIAA14 DLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAW ::::::::::::::::::::.:::::::::::.:::::::::::::::::.::::::::: gi|739 DLLKALKGLVVMSSQLELMATSLYNNTVPELWNAKAYPSLKPLSSWVMDLMQRLDFLQAW 4040 4050 4060 4070 4080 4090 4140 4150 4160 4170 4180 4190 KIAA14 IQDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVG :: :::::::::::::::::::::::::::: :::::::::::::: .. ::: .::. : gi|739 IQGGIPAVFWISGFFFPQAFLTGTLQNFARKSVISIDTISFDFKVMQQSVSELKKRPKEG 4100 4110 4120 4130 4140 4150 4200 4210 4220 4230 4240 4250 KIAA14 CYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLT ::::::::::::::: :::::::. ::::::::::::.:: :::.:::.::::::::::: gi|739 CYIHGLFLEGARWDPAAFQLAESRSKELYTEMAVIWLVPTHNRKTQDQNFYLCPIYKTLT 4160 4170 4180 4190 4200 4210 4260 4270 4280 4290 KIAA14 RAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALICALDY :::::::::::::::::::::..:::.::::::::::::::: gi|739 RAGTLSTTGHSTNYVIAVEIPSNQPQQHWIKRGVALICALDY 4220 4230 4240 4250 >>gi|119585622|gb|EAW65218.1| dynein, axonemal, heavy po (2455 aa) initn: 14430 init1: 11424 opt: 12338 Z-score: 12126.0 bits: 2258.6 E(): 0 Smith-Waterman score: 15188; 91.533% identity (93.328% similar) in 2563 aa overlap (1734-4293:1-2455) 1710 1720 1730 1740 1750 1760 KIAA14 SCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKIT :::::::::::::::::::::::::::::: gi|119 MMVPDYAMITEISLYSFGFNEASVLAKKIT 10 20 30 1770 1780 1790 1800 1810 1820 KIAA14 TTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQ 40 50 60 70 80 90 1830 1840 1850 1860 1870 1880 KIAA14 EDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVR 100 110 120 130 140 150 1890 1900 1910 1920 1930 1940 KIAA14 HGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 HGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEF 160 170 180 190 200 210 1950 1960 1970 1980 1990 2000 KIAA14 DLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DLLTHEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGE 220 230 240 250 260 270 2010 2020 2030 2040 2050 2060 KIAA14 IIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 IIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEE 280 290 300 310 320 330 2070 2080 2090 2100 2110 2120 KIAA14 HFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLL---KLLDCFFKPFLPREGLKKIP ::::::::::: :.:. .... .:: .: :: . : : ..::: gi|119 HFKALFVSFLE---------VSEATGTSQGELTAPQWAQGSLTDCS-RAF-P---VSKIP 340 350 360 370 2130 2140 2150 2160 2170 2180 KIAA14 SEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFD .. .:. : . .... : . : : . . .: :: . gi|119 TKPVSE-------W-----VLALAVPLDRALGLSVRSLLSICLGGET-----HFEGAQTQ 380 390 400 410 2190 2200 2210 2220 2230 2240 KIAA14 YRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHL : . .: ....:: . . : . . : : :... .: . gi|119 VSLSQ--LSQDTQNKDEGGSRHLAIWRR-LKFSKGF---PEAK-----LPPV-------- 420 430 440 450 460 2250 2260 2270 2280 2290 2300 KIAA14 LDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSK .: . :: . : . : gi|119 --------RPWILRGPGACGCWAHTAPPL------------------------------- 470 480 2310 2320 2330 2340 2350 2360 KIAA14 LDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ---RRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFK 490 500 510 520 530 2370 2380 2390 2400 2410 2420 KIAA14 NLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWL------ 540 550 560 570 580 590 2430 2440 2450 2460 2470 2480 KIAA14 KSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLM :::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 -------AGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLM 600 610 620 630 640 2490 2500 2510 2520 2530 2540 KIAA14 ADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQP 650 660 670 680 690 700 2550 2560 2570 2580 2590 2600 KIAA14 ILYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRIS :::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: gi|119 ILYGDFMSPGSDVKSYELITSESK---VIEEYIEDYNQINTAKLKLVLFMDAMSHICRIS 710 720 730 740 750 760 2610 2620 2630 2640 2650 2660 KIAA14 RTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 RTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKA 770 780 790 800 810 820 2670 2680 2690 2700 2710 2720 KIAA14 GLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQ 830 840 850 860 870 880 2730 2740 2750 2760 2770 2780 KIAA14 PTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 PTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKS 890 900 910 920 930 940 2790 2800 2810 2820 2830 2840 KIAA14 VATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLH 950 960 970 980 990 1000 2850 2860 2870 2880 2890 2900 KIAA14 IFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 IFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTME 1010 1020 1030 1040 1050 1060 2910 2920 2930 2940 2950 2960 KIAA14 QIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNK 1070 1080 1090 1100 1110 1120 2970 2980 2990 3000 3010 3020 KIAA14 NDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHF 1130 1140 1150 1160 1170 1180 3030 3040 3050 3060 3070 3080 KIAA14 LESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKA 1190 1200 1210 1220 1230 1240 3090 3100 3110 3120 3130 3140 KIAA14 VEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQC 1250 1260 1270 1280 1290 1300 3150 3160 3170 3180 3190 3200 KIAA14 EQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVL 1310 1320 1330 1340 1350 1360 3210 3220 3230 3240 3250 3260 KIAA14 YDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTH 1370 1380 1390 1400 1410 1420 3270 3280 3290 3300 3310 3320 KIAA14 FIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEP 1430 1440 1450 1460 1470 1480 3330 3340 3350 3360 3370 3380 KIAA14 VLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSG 1490 1500 1510 1520 1530 1540 3390 3400 3410 3420 3430 3440 KIAA14 LEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELI 1550 1560 1570 1580 1590 1600 3450 3460 3470 3480 3490 3500 KIAA14 KVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQY 1610 1620 1630 1640 1650 1660 3510 3520 3530 3540 3550 3560 KIAA14 SLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVR 1670 1680 1690 1700 1710 1720 3570 3580 3590 3600 3610 3620 KIAA14 IMMNEGKINQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 IMMNEGKINQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVK 1730 1740 1750 1760 1770 1780 3630 3640 3650 3660 3670 3680 KIAA14 HLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 HLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRF 1790 1800 1810 1820 1830 1840 3690 3700 3710 3720 3730 3740 KIAA14 IEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPR ::::..:::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 IEPQATNLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPR 1850 1860 1870 1880 1890 1900 3750 3760 3770 3780 3790 3800 KIAA14 AEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPV 1910 1920 1930 1940 1950 1960 3810 3820 3830 3840 3850 3860 KIAA14 SILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERR 1970 1980 1990 2000 2010 2020 3870 3880 3890 3900 3910 3920 KIAA14 KFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRR 2030 2040 2050 2060 2070 2080 3930 3940 3950 3960 3970 3980 KIAA14 CIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 CIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDN 2090 2100 2110 2120 2130 2140 3990 4000 4010 4020 4030 4040 KIAA14 ANITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ANITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKY 2150 2160 2170 2180 2190 2200 4050 4060 4070 4080 4090 4100 KIAA14 PVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 PVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVP 2210 2220 2230 2240 2250 2260 4110 4120 4130 4140 4150 4160 KIAA14 ELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFA 2270 2280 2290 2300 2310 2320 4170 4180 4190 4200 4210 4220 KIAA14 RKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 RKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELY 2330 2340 2350 2360 2370 2380 4230 4240 4250 4260 4270 4280 KIAA14 TEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHW 2390 2400 2410 2420 2430 2440 4290 KIAA14 IKRGVALICALDY ::::::::::::: gi|119 IKRGVALICALDY 2450 >>gi|148692857|gb|EDL24804.1| mCG3819 [Mus musculus] (3614 aa) initn: 15762 init1: 7675 opt: 11297 Z-score: 11099.5 bits: 2069.2 E(): 0 Smith-Waterman score: 21063; 84.888% identity (91.361% similar) in 3785 aa overlap (581-4293:1-3614) 560 570 580 590 600 610 KIAA14 VTAMSLFHSSLSKYSHLEEFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYN :::::::::::.::::::.::::::::::: gi|148 VQMFLKDSWISTLKVAMRGSLRDMSKGWYN 10 20 30 620 630 640 650 660 670 KIAA14 LYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVW ::::::::::::::::::::.::::::::::::::::.::.:::.:.:::::.:.::: : gi|148 LYETNWEVYLMSKLRKLMELIKYMLQDTLRFLVQDSLGSFTQFIGDACCSVLECVDDMDW 40 50 60 70 80 90 680 690 700 710 720 730 KIAA14 GDDLINSPYRPRKNPLFIMDLVLDSSGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEK :.::.:::: gi|148 GEDLVNSPY--------------------------------------------------- 740 750 760 770 780 790 KIAA14 LVMEDIFISGDPLLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDI gi|148 ------------------------------------------------------------ 800 810 820 830 840 850 KIAA14 ASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRK :::::: :.::::::.:::.::::::.::::::::::::::.:::::::::::: gi|148 ----KTYQTQCPSAEEVREVVITHLKEKEILDNSLPSSIIIGPFYINVDNVKQSLSKKRK 100 110 120 130 140 150 860 870 880 890 900 KIAA14 ALATSVLDILAKNLHKEVDS--------ICEEFRSISRKIYEKPNSIEELAELREWMKGI :::::.:::::::::::::: ::::::::::::::::::::::::::.::::: gi|148 ALATSMLDILAKNLHKEVDSNPPILTHQICEEFRSISRKIYEKPNSIEELAELRDWMKGI 160 170 180 190 200 210 910 920 930 940 950 960 KIAA14 PERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVED ::.:: :::::::::.::.:::::.:::..::::::: :.::::::::::..:.:::::: gi|148 PEKLVFLEERIVKVMSDYEVMDEFFYNLTTDDFNDKWAANNWPSKILGQIDMVRQQHVED 220 230 240 250 260 270 970 980 990 1000 1010 1020 KIAA14 EEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAM ::::::::.::::::::::::::::::::::::::.:::::::::::::::::::::::: gi|148 EEKFRKIQLMDQNNFQEKLEGLQLVVAGFSIHVEIARAHEIANEVRRVKKQLKDCQQLAM 280 290 300 310 320 330 1030 1040 1050 1060 1070 1080 KIAA14 LYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLE :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 LYNNRERIFGLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLE 340 350 360 370 380 390 1090 1100 1110 1120 1130 1140 KIAA14 KNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETL :::.:.:::::::::::::.:::::::::::.::::::::::::::::::::: ::::.: gi|148 KNVIESFKTMHKCVKQFKDIPACQEVALDIRTRIEEFKPYIPLIQGLRNPGMRNRHWEVL 400 410 420 430 440 450 1150 1160 1170 1180 1190 1200 KIAA14 SNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILF ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::.::: gi|148 SNEININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSSILF 460 470 480 490 500 510 1210 1220 1230 1240 1250 1260 KIAA14 NVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVL :::::: ::::::::::::::::::::::::.::::::::::::::::::.::::::::: gi|148 NVLPYKETDTYILKSPDEASQLLDDHIVMTQSMSFSPYKKPFEQRINSWETKLKLTQEVL 520 530 540 550 560 570 1270 1280 1290 1300 1310 1320 KIAA14 EEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDL ::::::::.:::::::::::::..::::::::::::::::.:::::::::::::::::: gi|148 EEWLNCQRAWLYLEPIFSSEDITRQLPVESKRYQTMERIWRKIMKNAYENREVINVCSDQ 580 590 600 610 620 630 1330 1340 1350 1360 1370 1380 KIAA14 RMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLR :.:::::::::.::::::::::::::::.::::::::::::::::::::::::::::::: gi|148 RLLDSLRDCNKLLDLVQKGLSEYLETKRTAFPRFYFLSDDELLEILSQTKDPTAVQPHLR 640 650 660 670 680 690 1390 1400 1410 1420 1430 1440 KIAA14 KCFENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIE ::::::::::::::::::::::::::::.: ::::::::::::: ::::::::::::::: gi|148 KCFENIARLLFQEDLEITHMYSAEGEEVKLSFSIYPSSNVEDWLLEVERSMKASVHDIIE 700 710 720 730 740 750 1450 1460 1470 1480 1490 1500 KIAA14 KAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQLFPQLCQQLSDLV ::.::::: ::.::::::::::::::::::::::::::::::. :.::::: .:::::: gi|148 MAIKAYPTMLRTEWVLNWPGQVTIAGCQTYWTMEVAEALEAGNISSKLFPQLSKQLSDLV 760 770 780 790 800 810 1510 1520 1530 1540 1550 1560 KIAA14 ALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTNNDLYI :::::::::::: ::::::::::::::::::::.::::::.::.::::::::::..:::: gi|148 ALVRGKLSRMQRMVLSALIVIEVHAKDVVSKLIDENVVSVHDFEWISQLRYYWTKDDLYI 820 830 840 850 860 870 1570 1580 1590 1600 1610 1620 KIAA14 RAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 RAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDL 880 890 900 910 920 930 1630 1640 1650 1660 1670 1680 KIAA14 GKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 GKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQ 940 950 960 970 980 990 1690 1700 1710 1720 1730 1740 KIAA14 KAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMI :::::: :::::::::::::::: gi|148 KAQQQR--------------------------------------ALFRPVAMMVPDYAMI 1000 1010 1750 1760 1770 1780 1790 1800 KIAA14 TEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPS .::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::. gi|148 AEISLYSFGFNEANVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPT 1020 1030 1040 1050 1060 1070 1810 1820 1830 1840 1850 1860 KIAA14 MNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSN :::::::::::::::::::::::::::::::::::::::::.:::::::.:::..:...: gi|148 MNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEETDYGILDQAIRRSCEKNN 1080 1090 1100 1110 1120 1130 1870 1880 1890 KIAA14 LKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKST-----------------------C :::::::: ::::::::::::::::::::::::::. : gi|148 LKDVEGFLIKCIQLYETTVVRHGLMLVGPTGSGKSNSPNPLHPCSLRSQEGHFLVVTPQC 1140 1150 1160 1170 1180 1190 1900 1910 1920 1930 1940 1950 KIAA14 YRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFI ::::::::: :::.::::::.:::::::::::::::::::::::::::::::::::::.: gi|148 YRVLAAAMTLLKGKPSISGGVYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSLI 1200 1210 1220 1230 1240 1250 1960 1970 1980 1990 2000 2010 KIAA14 RAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQD :::::.::::::::::::::::.::::::::::::::::::::::::::::::::::::: gi|148 RAGAIASDTNKKWYMFDGPVDAVWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQD 1260 1270 1280 1290 1300 1310 2020 2030 2040 2050 2060 2070 KIAA14 LAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISF :::::::::::::::::::::::::::.::::..:: ..:::::.::.::...::.::.: gi|148 LAVASPATVSRCGMVYLEPSILGLMPFVECWLKRLPAIIKPYEEQFKSLFTKYLENSINF 1320 1330 1340 1350 1360 1370 2080 2090 2100 2110 2120 2130 KIAA14 VRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSL ::..::::::::: ::::::::::::::.:::::::::::::::::.: ::::::::::: gi|148 VRNTVKEVIASTNSNLTMSLLKLLDCFFRPFLPREGLKKIPSEKLSHIPELIEPWFIFSL 1380 1390 1400 1410 1420 1430 2140 2150 2160 2170 2180 2190 KIAA14 IWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEE .:::::::: ..: :::.::::::. ::. : :::.:::.::::.:::::.:.:...::. gi|148 VWSVGATGDHTSRISFSQWLRLKMRLEQVKLGFPEDGLVYDYRLDDAGISSTEDDDEEED 1440 1450 1460 1470 1480 1490 2200 2210 2220 2230 2240 2250 KIAA14 EYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGT : :::.:::::: ::::::.:::::::::::::::::::.:: :::::.::::::::::: gi|148 ENKQVSWVKWMDYSAPFTMMPDTNYCNIIVPTMDTVQMSYLLGMLLTNHKPVLCIGPTGT 1500 1510 1520 1530 1540 1550 2260 2270 2280 2290 2300 KIAA14 GKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKR--------------- :::::.:.:::: : :.:::::::::::::::::::.:::::::: gi|148 GKTLTVSNKLLKYLPLEYISHFLTFSARTSANQTQDLIDSKLDKRQDTPGSFHSHSSAVS 1560 1570 1580 1590 1600 1610 2310 2320 2330 KIAA14 --------------------------RKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPI :::::::::::::::::::::::::::::::::: gi|148 SPHLILLLALAEMAPQEPESPTGDLRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPI 1620 1630 1640 1650 1660 1670 2340 2350 2360 2370 2380 2390 KIAA14 ELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMD ::::::::::::::::.::::::::::::::::::::::::..:::: :::::::: ::: gi|148 ELLRQWMDHGGWYDRKVIGAFKNLVDINFVCAMGPPGGGRNAITPRLTRHFNYLSFIEMD 1680 1690 1700 1710 1720 1730 2400 2410 2420 2430 2440 2450 KIAA14 EVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPT ::::::::: :: :. :::.: .:::::.::: ::. :::::::: gi|148 EVSKKRIFSIILECWM-------------AGAPNIDDLTEPLVDATINVYGIITSQLLPT 1740 1750 1760 1770 1780 2460 2470 2480 2490 2500 2510 KIAA14 PAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFD :::::::::::::::::::::::.:.::::.::::::::::::::::::::::::::::: gi|148 PAKSHYTFNLRDLSKVFQGMLMAEPSKVEDKVQLLRLWYHENCRVFRDRLVNEEDRSWFD 1790 1800 1810 1820 1830 1840 2520 2530 2540 2550 2560 2570 KIAA14 QLLKRCMEQWEVTFNKVCPFQPILYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQ .::. ::.. :.:::::::::::::::::::::::::::::::::::::::::.::::: gi|148 ELLEAQMEEFGVAFNKVCPFQPILYGDFMSPGSDVKSYELITSESKMMQVIEEYMEDYNQ 1850 1860 1870 1880 1890 1900 2580 2590 2600 2610 2620 2630 KIAA14 INTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQI ::::::.::::.:::::::::::::::::::::::::::::::::::::::::::::::: gi|148 INTAKLRLVLFVDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQI 1910 1920 1930 1940 1950 1960 2640 2650 2660 2670 2680 2690 KIAA14 ELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLY ::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::.: gi|148 ELSKNYGMSEWREDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNIY 1970 1980 1990 2000 2010 2020 2700 2710 2720 2730 2740 2750 KIAA14 TADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQF .:::::::..:::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 SADEQDQIINTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQF 2030 2040 2050 2060 2070 2080 2760 2770 2780 2790 2800 2810 KIAA14 PSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCI :::::::::::::::::::::::::.::.:::::: :.: :::::::::.:::::..::. gi|148 PSLVNCCTIDWFNEWPAEALKSVATTFLSEIPELECSEEVIQGLIQVCVFIHQSVASKCV 2090 2100 2110 2120 2130 2140 2820 2830 2840 2850 2860 2870 KIAA14 EYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQ ::::::.::::::::::::::.::::::::::.::::::::::::::::::::::::::: gi|148 EYLAELARHNYVTPKSYLELLNIFSILIGQKKMELKTAKNRMKSGLDKLLRTSEDVAKMQ 2150 2160 2170 2180 2190 2200 2880 2890 2900 2910 2920 2930 KIAA14 EDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQ :.:: :.::::::::::::::::::::::::::::.:::.:::::::::.:::::::::: gi|148 EELEIMRPLLEEAAKDTMLTMEQIKVDTAIAEETRKSVQAEEIKANEKANKAQAIADDAQ 2210 2220 2230 2240 2250 2260 2940 2950 2960 2970 2980 2990 KIAA14 KDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 KDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEK 2270 2280 2290 2300 2310 2320 3000 3010 3020 3030 3040 3050 KIAA14 PGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVS ::.:::::::::::::::::.::::::::::::::..:::::::::::::::::.::::: gi|148 PGSKVDDYWEPGKGLLQDPGRFLESLFKFDKDNIGEAVIKAIQPYIDNEEFQPAAIAKVS 2330 2340 2350 2360 2370 2380 3060 3070 3080 3090 3100 3110 KIAA14 KACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIAT :::::::::::::::::::::::::::::: :::::: ::::::.:::..:.:::::::: gi|148 KACTSICQWVRAMHKYHFVAKAVEPKRQALREAQDDLEVTQRILEEAKHHLHEVEDGIAT 2390 2400 2410 2420 2430 2440 3120 3130 3140 3150 3160 3170 KIAA14 MQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGD ::::::::..::::::.:::::::::::: ::::::.:::::::::::::. ::.:: :: gi|148 MQAKYRECVAKKEELEMKCEQCEQRLGRADKLINGLADEKVRWQETVENLENMLDNIFGD 2450 2460 2470 2480 2490 2500 3180 3190 3200 3210 3220 3230 KIAA14 VLVAAGFVAYLGPFTGQYRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAG ::::::::::::::::::::.::. ::.:: :.:::::.:::: ::::::::::::::: gi|148 VLVAAGFVAYLGPFTGQYRTTLYEYWVNQLTVHHVPHTSKPTLITTLGNPVKIRSWQIAG 2510 2520 2530 2540 2550 2560 3240 3250 3260 3270 3280 3290 KIAA14 LPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENA :::::::::::::::::::::::::::.::::::::::...::::::::::::::::::: gi|148 LPNDTLSVENGVINQFSQRWTHFIDPQGQANKWIKNMERESGLDVFKLSDRDFLRSMENA 2570 2580 2590 2600 2610 2620 3300 3310 3320 3330 3340 3350 KIAA14 IRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPN :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: gi|148 IRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNIVLKLGDTVIPYHEDFRMYITTKLPN 2630 2640 2650 2660 2670 2680 3360 3370 3380 3390 3400 3410 KIAA14 PHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDI :::.:::::::::::::::::::::::::::::::::::::::::::.:::::::::::: gi|148 PHYSPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIVSNAKMRQELKDI 2690 2700 2710 2720 2730 2740 3420 3430 3440 3450 3460 3470 KIAA14 EDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 EDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVA 2750 2760 2770 2780 2790 2800 3480 3490 3500 3510 3520 3530 KIAA14 IRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLY .::::::::::::::::::::::::::::::::::::::::::::::: :::::::.::: gi|148 VRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRIVNINRYLTFSLY 2810 2820 2830 2840 2850 2860 3540 3550 3560 3570 3580 3590 KIAA14 SNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPDWLSDRA ::::::::::::::::::::::::::::::::.:::::::::::. : :::::.:::::: gi|148 SNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQAEWRYLLSGGSIQTMFENPAPQWLSDRA 2870 2880 2890 2900 2910 2920 3600 3610 3620 3630 3640 3650 KIAA14 WRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRC :::::::::::::..::.::: .::::..:::: ::::: :::::. :::.:::::.::: gi|148 WRDILALSNLPTFATFSNDFVMYLSEFQAIFDSAEPHRELLPGIWNAYLDEFQKLLILRC 2930 2940 2950 2960 2970 2980 3660 3670 3680 3690 3700 3710 KIAA14 LRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKF ::::::::::::::::.:::::::::. .::.:::::::::::::::::::::::: gi|148 LRGDKVTNAMQDFVATHLEPRFIEPQA-----MFKESNSTTPLIFVLSPGTDPAADLYKF 2990 3000 3010 3020 3030 3720 3730 3740 3750 3760 3770 KIAA14 AEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHIN :::::::::.::::::::::::::::::.::::::::::::::::::::::::::::::: gi|148 AEEMKFSKKFSAISLGQGQGPRAEAMMRNSIERGKWVFFQNCHLAPSWMPALERLIEHIN 3040 3050 3060 3070 3080 3090 3780 3790 3800 3810 3820 3830 KIAA14 PDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHK :::::::::::::::::::::::::::::::::::::::.:::::::.::..:::.::.: gi|148 PDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVKANLLKSYNSLSDDFLHSCQK 3100 3110 3120 3130 3140 3150 3840 3850 3860 3870 3880 3890 KIAA14 VMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYK :.::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: gi|148 VVEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYEDIPYK 3160 3170 3180 3190 3200 3210 3900 3910 3920 3930 3940 3950 KIAA14 VLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHG :::::::::::::::::::::::.:::::::::: ::: ::::: :::::::::::::.: gi|148 VLKYTAGEINYGGRVTDDWDRRCVMNILEDFYNPAVLSSEHSYSNSGIYHQIPPTYDLNG 3220 3230 3240 3250 3260 3270 3960 3970 3980 3990 4000 4010 KIAA14 YLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVED :::::::::::::::::::::::::::::::::::...:.:::::::: :.:.:::.::: gi|148 YLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALFNAILQLQPKSSSMGGQSREELVED 3280 3290 3300 3310 3320 3330 4020 4030 4040 4050 4060 4070 KIAA14 VTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALK :..::::.:: ::.:: : :.::::::::::::::::::::.::.::::::.:.:::.: gi|148 VAENILLQVPGPIELQEVTKKFPVLYEESMNTVLVQEVIRYNKLLEVITQTLSDMLKAIK 3340 3350 3360 3370 3380 3390 4080 4090 4100 4110 4120 4130 KIAA14 GLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPA :::::: .::::. :::::::::::..:::::::::.::.:::: ::::...::.:::: gi|148 GLVVMSLELELMSISLYNNTVPELWKSKAYPSLKPLASWIMDLLLRLDFMHSWINDGIPP 3400 3410 3420 3430 3440 3450 4140 4150 4160 4170 4180 4190 KIAA14 VFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLF ::::::::::::::::::::::::::::::::.:::::. :: ::. .:::.:::::::: gi|148 VFWISGFFFPQAFLTGTLQNFARKFVISIDTITFDFKVLPEASSEIKERPQTGCYIHGLF 3460 3470 3480 3490 3500 3510 4200 4210 4220 4230 4240 4250 KIAA14 LEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLST ::::::: ::::::.::::::::::::::: :::.:.:::::::::::::::::::: gi|148 LEGARWDSMNFQLAESRPKELYTEMAVIWLLPEANRKVQNQDFYLCPIYKTLTRAGTLST 3520 3530 3540 3550 3560 3570 4260 4270 4280 4290 KIAA14 TGHSTNYVIAVEIPTHQPQRHWIKRGVALICALDY ::::::::::::::..::::::::::::::::::: gi|148 TGHSTNYVIAVEIPSNQPQRHWIKRGVALICALDY 3580 3590 3600 3610 >>gi|149034184|gb|EDL88954.1| rCG42293 [Rattus norvegicu (1950 aa) initn: 7647 init1: 7647 opt: 11269 Z-score: 11075.8 bits: 2064.0 E(): 0 Smith-Waterman score: 11825; 89.075% identity (96.900% similar) in 1968 aa overlap (2326-4293:1-1950) 2300 2310 2320 2330 2340 2350 KIAA14 FIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKI :::::::::::::::::::::::::::::: gi|149 MPALETYGAQPPIELLRQWMDHGGWYDRKI 10 20 30 2360 2370 2380 2390 2400 2410 KIAA14 IGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLD ::::::::::::::::::::::::..:::: :::::::: :::::::::::: ::: :. gi|149 IGAFKNLVDINFVCAMGPPGGGRNAITPRLTRHFNYLSFIEMDEVSKKRIFSIILGCWM- 40 50 60 70 80 2420 2430 2440 2450 2460 2470 KIAA14 GLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVF :::.:.:.:::::.::: .:: ::::::::::::::::::::::::: gi|149 ------------AGAPNIVHMTEPLVNATISIYAIITSQLLPTPAKSHYTFNLRDLSKVF 90 100 110 120 130 2480 2490 2500 2510 2520 2530 KIAA14 QGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKV ::.:::.::::::.:::::::::::::::::::::::::.::: ::. ::. :.:::: gi|149 QGILMAEPAKVEDKVQLLRLWYHENCRVFRDRLVNEEDRGWFDGLLEMKMEDLGVAFNKV 140 150 160 170 180 190 2540 2550 2560 2570 2580 2590 KIAA14 CPFQPILYGDFMSPGSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSH :::::::::::::::::::::::::::.:::::::::.::::::::::::::::.::::: gi|149 CPFQPILYGDFMSPGSDVKSYELITSENKMMQVIEEYMEDYNQINTAKLKLVLFVDAMSH 200 210 220 230 240 250 2600 2610 2620 2630 2640 2650 KIAA14 ICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKK ::::::::::::::::::::::::::::::::::::::::::.::::::::::::.:::: gi|149 ICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQVELSKNYGMSEWREDVKK 260 270 280 290 300 310 2660 2670 2680 2690 2700 2710 KIAA14 VLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQ .:::::.:::::::::::::::::::::::::.::::::::::.::::::::.::::::: gi|149 ILLKAGMQNLPITFLFSDTQIKNESFLEDINNILNSGDIPNLYSADEQDQIVNTMRPYIQ 320 330 340 350 360 370 2720 2730 2740 2750 2760 2770 KIAA14 EQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPA ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: gi|149 EQGLQPTKANLMAAYTGRVRNNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPA 380 390 400 410 420 430 2780 2790 2800 2810 2820 2830 KIAA14 EALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSY :::.:::: ::.:::::: :.: :.:::.:::::::::.:::.::::::.:::::::::: gi|149 EALQSVATRFLHEIPELECSSEVIEGLIHVCVYIHQSVAKKCVEYLAELARHNYVTPKSY 440 450 460 470 480 490 2840 2850 2860 2870 2880 2890 KIAA14 LELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDT ::::.::::::::::.::::::.:::::::::::::::::::::.:: :.:::::::::: gi|149 LELLNIFSILIGQKKMELKTAKHRMKSGLDKLLRTSEDVAKMQEELEIMRPLLEEAAKDT 500 510 520 530 540 550 2900 2910 2920 2930 2940 2950 KIAA14 MLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASL .:::.:::::::::::::.:::.:::::::::.::::::::::::::::::::::::::: gi|149 LLTMDQIKVDTAIAEETRKSVQAEEIKANEKASKAQAIADDAQKDLDEALPALDAALASL 560 570 580 590 600 610 2960 2970 2980 2990 3000 3010 KIAA14 RNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQ :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: gi|149 RNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGSKVDDYWEPGKGLLQ 620 630 640 650 660 670 3020 3030 3040 3050 3060 3070 KIAA14 DPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYH :::.::::::::::::::..:::::::::::::::::.:::::::::::::::::::::: gi|149 DPGRFLESLFKFDKDNIGEAVIKAIQPYIDNEEFQPAAIAKVSKACTSICQWVRAMHKYH 680 690 700 710 720 730 3080 3090 3100 3110 3120 3130 KIAA14 FVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELEL ::::::::::::: :::::: ::::::.:::..::::::::.:.:::::::.:::::::. gi|149 FVAKAVEPKRQALREAQDDLEVTQRILEEAKHHLREVEDGISTLQAKYRECVTKKEELEM 740 750 760 770 780 790 3140 3150 3160 3170 3180 3190 KIAA14 KCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQ :::::::::::: ::::::.:::::::.:::::. ::.:: ::::::::::::::::::: gi|149 KCEQCEQRLGRADKLINGLADEKVRWQDTVENLENMLDNIFGDVLVAAGFVAYLGPFTGQ 800 810 820 830 840 850 3200 3210 3220 3230 3240 3250 KIAA14 YRTVLYDSWVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFS ::..::. ::.:: ..:::::.::::.:::::::::::::::::::::::::::::::: gi|149 YRAALYEYWVNQLTVYGVPHTSKPTLISTLGNPVKIRSWQIAGLPNDTLSVENGVINQFS 860 870 880 890 900 910 3260 3270 3280 3290 3300 3310 KIAA14 QRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELD ::::::::::.:::::::::::..:::::::::::::::::::::::::::::::::::: gi|149 QRWTHFIDPQGQANKWIKNMEKESGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELD 920 930 940 950 960 970 3320 3330 3340 3350 3360 3370 KIAA14 PALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFT ::::::::::::::::::::::::::::::::::::::::::::::.::.:::::::::: gi|149 PALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYSPEVSTKLTLINFT 980 990 1000 1010 1020 1030 3380 3390 3400 3410 3420 3430 KIAA14 LSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|149 LSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVD 1040 1050 1060 1070 1080 1090 3440 3450 3460 3470 3480 3490 KIAA14 DMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVD :.:::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: gi|149 DVELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAVRTQILFFCVSDLANVD 1100 1110 1120 1130 1140 1150 3500 3510 3520 3530 3540 3550 KIAA14 PMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAF ::::::::::::::::::::::::::::::: :::::::.:::::::::::::::::::: gi|149 PMYQYSLEWFLNIFLSGIANSERADNLKKRIVNINRYLTFSLYSNVCRSLFEKHKLMFAF 1160 1170 1180 1190 1200 1210 3560 3570 3580 3590 3600 3610 KIAA14 LLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAPDWLSDRAWRDILALSNLPTFSSFS :::::::::::::::.:::::::::::. :.::::: :::::::::::::::::.::.:: gi|149 LLCVRIMMNEGKINQGEWRYLLSGGSIQTMSENPAPHWLSDRAWRDILALSNLPAFSTFS 1220 1230 1240 1250 1260 1270 3620 3630 3640 3650 3660 3670 KIAA14 SDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATN .:::.:: .:..:::: :::::::::::. :::.:::::.::::::::::::::::::.. gi|149 TDFVQHLPKFQAIFDSAEPHREPLPGIWNTYLDEFQKLLILRCLRGDKVTNAMQDFVANH 1280 1290 1300 1310 1320 1330 3680 3690 3700 3710 3720 3730 KIAA14 LEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQ :::::::::. .::.::::::::::::::::::::::::::::::::::::::::: gi|149 LEPRFIEPQA-----MFKESNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQ 1340 1350 1360 1370 1380 1390 3740 3750 3760 3770 3780 3790 KIAA14 GQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPS :::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::: gi|149 GQGPRAEAMMRNSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPS 1400 1410 1420 1430 1440 1450 3800 3810 3820 3830 3840 3850 KIAA14 NKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGN ::::::::::::::::::::::.:::::::.::..:::.::.::.::::::::::::::: gi|149 NKFPVSILQNGSKMTIEPPRGVKANLLKSYNSLSDDFLHSCQKVVEFKSLLLSLCLFHGN 1460 1470 1480 1490 1500 1510 3860 3870 3880 3890 3900 3910 KIAA14 ALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTD :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|149 ALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYEDIPYKVLKYTAGEINYGGRVTD 1520 1530 1540 1550 1560 1570 3920 3930 3940 3950 3960 3970 KIAA14 DWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIF ::::::.:::::::::: :::::: :: :::::::::::::.:::::::::::::::::: gi|149 DWDRRCVMNILEDFYNPAVLSPEHRYSKSGIYHQIPPTYDLNGYLSYIKSLPLNDMPEIF 1580 1590 1600 1610 1620 1630 3980 3990 4000 4010 4020 4030 KIAA14 GLHDNANITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQW ::::::::::::::::::.:.:.:::::::: :.:.:::.::::...::..::.:..:. gi|149 GLHDNANITFAQNETFALFGAILQLQPKSSSMGGQSREELVEDVAEDILVQVPKPVDLEE 1640 1650 1660 1670 1680 1690 4040 4050 4060 4070 4080 4090 KIAA14 VMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLY :. ::::::::::::::::::::::.::.::::::.:.:::.::::::: .::::..::: gi|149 VVNKYPVLYEESMNTVLVQEVIRYNKLLMVITQTLSDMLKAIKGLVVMSLELELMSTSLY 1700 1710 1720 1730 1740 1750 4100 4110 4120 4130 4140 4150 KIAA14 NNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGT ::.:::::..:::::::::.::.:::::::.::..::..:::.::::::::::::::::: gi|149 NNAVPELWKSKAYPSLKPLASWIMDLLQRLNFLHSWIKNGIPSVFWISGFFFPQAFLTGT 1760 1770 1780 1790 1800 1810 4160 4170 4180 4190 4200 4210 KIAA14 LQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQ :::::::::::::::.:::::. : ::...::..::::.::::::::::: ::::::. gi|149 LQNFARKFVISIDTITFDFKVLSYASSEIAERPSTGCYIYGLFLEGARWDPFDFQLAESR 1820 1830 1840 1850 1860 1870 4220 4230 4240 4250 4260 4270 KIAA14 PKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQ :::::::::::::::. :::.:.::::::::::::::::::::::::::::::::::..: gi|149 PKELYTEMAVIWLLPVANRKVQNQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPSNQ 1880 1890 1900 1910 1920 1930 4280 4290 KIAA14 PQRHWIKRGVALICALDY :::::::::::::::::: gi|149 PQRHWIKRGVALICALDY 1940 1950 >>gi|163777893|gb|EDQ91509.1| predicted protein [Monosig (4070 aa) initn: 12844 init1: 4285 opt: 11074 Z-score: 10879.4 bits: 2028.7 E(): 0 Smith-Waterman score: 15509; 55.760% identity (80.160% similar) in 4123 aa overlap (200-4293:1-4070) 170 180 190 200 210 220 KIAA14 PEDFQERMEQQCIGSTTRLLAQTDFPLQAYEPKMQVPFQVLPGQHPRKIEIERRKQQYLS :::.: . . : ::.::.::::.:. . gi|163 EPKVQKEYAMREGAVPRRIEVERRKRQFAA 10 20 30 230 240 250 260 270 280 KIAA14 LDIEQLLFSQGIDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLKVFDNEDFDCRTPREW : .:: : ...:.: : .: : . .:::. ::..::: : :.:: gi|163 KTIAELLSEADIANHELLP-----AGPFRVEAQHLDTYNAFLPLEFFDDDDFDDRLPEEW 40 50 60 70 80 290 300 310 320 330 340 KIAA14 INMGL-EPGSLDRKPVPGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLVH ...:. : :.. :: .:. .:. :.. : . . : : :..:: :... : gi|163 VSLGVDEQGQM--LGVPVYSLMRNDE--GERLLLSGRSQVTWMEGRVISYDASKQVF--H 90 100 110 120 130 350 360 370 380 390 400 KIAA14 KTDEKGLVRDEMGRPILNAGVTTEGRPPLQVCQYWVPRIQLLFCAEDPCMFAQRVVQANA ::: ..:.:: :: :: : : :::: .: .:.. : . gi|163 -------VRDAH-----DSGATTWKRP----------RILLQFHAEDPEVFCNRITAAIT 140 150 160 170 410 420 430 440 450 460 KIAA14 LRKNTEALLLYNLYVDCMPSDGQHVISEQSLSKIKQ-WALSTPRMRKGPSVLEHLSSLAR ::. :::.: ::: ::::: :. ... . . . . . : .: :. . : . gi|163 LRRATEAMLQYNLTVDCMPVDAGISVTDLDAAIVDNVLRMIGPLAKKRPA---QTHELLQ 180 190 200 210 220 230 470 480 490 500 510 KIAA14 EVSLDYERSMNKINFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVP-----------K ...: :.: :.. . ... .. . . . ...:. . ..: . gi|163 DLQLAYNRCNNNMLMHNLLRQERHDLLLQGVKTPSANMIPNGHVPALPSTTRALQELGDR 240 250 260 270 280 290 520 530 540 550 560 570 KIAA14 YHFWEQKEDFTFVSLLTRPEVITALSKVRAECNKVTAMSLFHSSLSKYSHLEEFEQIQSQ : .:.. .... .:.:. :: .:.:::.:. ::.. : : ..:: :: : gi|163 LDFRVAREQIMKLTFIQEPRVVQALIRVHAECDKLMLRPLFNTHLHKCVTMDEFSTIQRQ 300 310 320 330 340 350 580 590 600 610 620 630 KIAA14 TFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMELVKYMLQ :: :.. ..:..: : . . :..:..:::::: : . ..: .::::.. .. :.: gi|163 TFEQLRNYIKNAWAPSSRHEVLRSIQDLGKGWYNLQERDQQAYDNGKLRKFFCGIRLMMQ 360 370 380 390 400 410 640 650 660 670 680 690 KIAA14 DTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPY-RPRKNPLFIMDLVLDS :.:: .. ::: . ... .. :. :. .::: ..: . : .:.: :.:.. . gi|163 DALRSVATDSLQELLRLVESASTRVIA-HDSSAWGDHPLDSKHLAPDGSPIFAMELIVGD 420 430 440 450 460 470 700 710 720 730 740 750 KIAA14 SGV-HYSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDPLLESVGLHEPLV .:: . .: :.: ::: .:. : ::..: .:. .: : : :..: .:: . gi|163 GGVVTFRESPARFAADLDNLFLEGLQAIANVPDMEAQIMNHLFWVGTPQLDTVHKNEPWI 480 490 500 510 520 530 760 770 780 790 800 810 KIAA14 EELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTH : :. . :.. : :: :: .:... .: . :. ... ..... .... : gi|163 LMARKTLENCVQECMKPLVDYAAQYERFRDLIDLDVKAYVANFNADEKDPADIKKECQKH 540 550 560 570 580 590 820 830 840 850 860 870 KIAA14 LREKEILDSSLPSSIIIGPFYINTDNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEE : . : .:.: :. :: :.. :... .: ::. :: :.::.: . : ...: .: gi|163 TIEARKLADSIPLSVDIGMFHVRCDGIRTQLMGKRRQLAHSLLDVLQQRLLGQASSANKE 600 610 620 630 640 650 880 890 900 910 920 930 KIAA14 FRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDD :.... .: :.::.:.. ::.::.::. . .:: . :.. :...:::: :::. : gi|163 FQKMANVLYTPVNGIEDLTDKREFMKSIPDTVKSLEGGVKKALADWELMDEFQLNLSDGD 660 670 680 690 700 710 940 950 960 970 980 990 KIAA14 FNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIH : .: :: :. .: . .. :::.: . : ..: .....::..::.:. : gi|163 FALRWQLYAWPRKMHELLESTYDSLKADEERFIENLHTDTKDFADNINSLQMLVASFGQH 720 730 740 750 760 770 1000 1010 1020 1030 1040 1050 KIAA14 VEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDL ..:.: ...: :.:...: ::: : :..::::::. .: .::::.:.: .:::.:. .: gi|163 TDIGRCEHVAVEARKIHKALKDAQAQAQVYNNRERLSNLQVTNYDHLNRCAKEFEPFKNL 780 790 800 810 820 830 1060 1070 1080 1090 1100 1110 KIAA14 WTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRA : :...::. . :::: .. .: : :: ....: ::. :: :.::..:.: .: . . gi|163 WLTTDEWLKSHKIWMNDSFADLDPEALEVQITNASKTILKCSKSFKELPGCLAIAQTVSG 840 850 860 870 880 890 1120 1130 1140 1150 1160 1170 KIAA14 RIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESIS :::::::.::::.::::::: :::: ::. ....:.: ...:: : ::..:..:...:. gi|163 WIEEFKPYVPLIQALRNPGMRERHWEQLSEAVGFDVKPDSSFTFQRVLELQLEQHMDTIT 900 910 920 930 940 950 1180 1190 1200 1210 1220 1230 KIAA14 KVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQN .:.:.:::::.::::::::: ::. ...... :: : : :.:: .::.::::::::::: gi|163 RVGEIAGKEYGIEQALDKMEAEWQPLVLEIIDYKETGTCIMKSAEEAAQLLDDHIVMTQA 960 970 980 990 1000 1010 1240 1250 1260 1270 1280 1290 KIAA14 MSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKR :::::.:.::::::.::.:::..::.::.:: .:::::::::::::::::..:::.:::: gi|163 MSFSPFKQPFEQRITSWDNKLRVTQDVLDEWATCQRSWLYLEPIFSSEDIQRQLPTESKR 1020 1030 1040 1050 1060 1070 1300 1310 1320 1330 1340 1350 KIAA14 YQTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFP :: :. .:.. : : .. .. :.: ..:...:.:::.:: :::::: ::::::..:: gi|163 YQKMDAMWRRTMDAARRTPGIVRFCADAKLLETFRECNKLLDQVQKGLSAYLETKRGVFP 1080 1090 1100 1110 1120 1130 1360 1370 1380 1390 1400 1410 KIAA14 RFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYSAEGEEVQLCF ::::::::::::::::::::::::::.::::.::::: :..::..... ::.:: : . gi|163 RFYFLSDDELLEILSQTKDPTAVQPHMRKCFDNIARLKFEDDLQMSEFVSADGESVVFRE 1140 1150 1160 1170 1180 1190 1420 1430 1440 1450 1460 1470 KIAA14 SIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWT ..::..:::.:: :::: : .:...:...:. : . :::..:. ::::..:::::: :: gi|163 DLYPKGNVEEWLLEVERVMAVSLRQILQEALGQYYAGPRTDFVIAWPGQIVIAGCQTTWT 1200 1210 1220 1230 1240 1250 1480 1490 1500 1510 1520 1530 KIAA14 MEVAEALEAGNLRSQLFP-QLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSK :: .:..:: : . :. :::::::::::::...:: ::::::::::::::::.. gi|163 SEVEKAIQAGAQGLQDYSEQMRAQLSDLVALVRGKLTKIQRKVLSALIVIEVHAKDVVAN 1260 1270 1280 1290 1300 1310 1540 1550 1560 1570 1580 KIAA14 LIQENVVSVNDFQWISQLRYYWTNND------LYIRAVNAEFIYGYEYLGNSGRLVITPL . ..: :.::.::::::::: ..: :.:.:::: : ::::::::::::::::: gi|163 MCTQGVSRVSDFEWISQLRYYWEQDDRPHGEDLHIKAVNAVFNYGYEYLGNSGRLVITPL 1320 1330 1340 1350 1360 1370 1590 1600 1610 1620 1630 1640 KIAA14 TDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKF :::::::::::: : .:::::::::::::::::::.::.::: ::::::::::.:::::: gi|163 TDRCYLTLTGALALIYGGAPAGPAGTGKTETTKDLAKAMAIQCVVFNCSDQLDYMAMGKF 1380 1390 1400 1410 1420 1430 1650 1660 1670 1680 1690 1700 KIAA14 FKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAV ::::::::::::::::::::::::::::::..:::.: ..: :::::::.. : .:: gi|163 FKGLASAGAWACFDEFNRIDIEVLSVVAQQVATIQQAVRNRETRFMFEGVDLSLKWTCAP 1440 1450 1460 1470 1480 1490 1710 1720 1730 1740 1750 1760 KIAA14 FITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFK :::::::::::::::::: ::::::::::::::::.:: ::::::..:..:.:::::.:: gi|163 FITMNPGYAGRTELPDNLAALFRPVAMMVPDYAMIAEIMLYSFGFDDAKALSKKITTVFK 1500 1510 1520 1530 1540 1550 1770 1780 1790 1800 1810 1820 KIAA14 LSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLK ::::::::::::::::::::::::::::::: .:.:..: :::::.::::::: .:: gi|163 LSSEQLSSQDHYDFGMRAVKTVISAAGNLKRAFLTMQEDVIVLRAIREVNVPKFLADDLV 1560 1570 1580 1590 1600 1610 1830 1840 1850 1860 1870 1880 KIAA14 LFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLM ::.:::::::: . ..::: :: :::::: . .:. :..:.:: :::::::::::::: gi|163 LFNGIVSDLFPRTQIPEVDYGALDVAIREACATHHLQPVDNFVTKVIQLYETTVVRHGLM 1620 1630 1640 1650 1660 1670 1890 1900 1910 1920 1930 1940 KIAA14 LVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLT :::::::::. ::.::..:.:.:.:::. ::..:. :. .:::::::::::::: :: .: gi|163 LVGPTGSGKTRCYEVLSTALTALQGQPTSSGSVYQPVHNFVLNPKSITMGQLYGAFDEMT 1680 1690 1700 1710 1720 1730 1950 1960 1970 1980 1990 2000 KIAA14 HEWTDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKL :::::::.:..:: :. .. ..::..:::::::::::::::::::::::::.::::: : gi|163 HEWTDGILSTLIRRGVAANTEDEKWFLFDGPVDAIWIENMNTVLDDNKKLCLASGEIIAL 1740 1750 1760 1770 1780 1790 2010 2020 2030 2040 2050 2060 KIAA14 TEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRK-LPPLLKPYEEHFK : : :.:::.::.:::::::::::::::::::::: ::. ::.. :: :..:. .. gi|163 TPEMRMIFEVEDLVVASPATVSRCGMVYLEPSILGLEPFVTSWLESSLPQLIQPHATTLQ 1800 1810 1820 1830 1840 1850 2070 2080 2090 2100 2110 2120 KIAA14 ALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSR :: ...:..: ::: :..:.. ... .:. .:.:::::.: :.. :.: . ::...:. gi|163 MLFDTYMEDAIHFVRRSTREIVQTVDSQLATGLMKLLDCLFAPYVERDGYR-IPARRLTA 1860 1870 1880 1890 1900 1910 2130 2140 2150 2160 2170 2180 KIAA14 IVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDA . ..:: ::...:.:::::: :. :::.:. ::: :: .... . ::: ::.:.: : gi|163 LPDMIEGWFFIALVWSVGATCDDEGRTKFDGWLRQKMAEHKVKMPFPEGLTVFEYQLIDD 1920 1930 1940 1950 1960 1970 2190 2200 2210 2220 2230 2240 KIAA14 GISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLT : . :.: : ..: .:.:: . : . :.... .:.:::.:::..: ... :.. gi|163 GSFDEASEEEESESPVPIGWKRWVDSLGDFIVNPSSQFNTIFVPTLDTVRYSWVVEKLVS 1980 1990 2000 2010 2020 2030 2250 2260 2270 2280 2290 2300 KIAA14 NKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRK :.:::: .:::::.::::...:::... ....: ..::::::::::::.::.::::::: gi|163 NSKPVLGVGPTGTAKTLTMANKLLREMPQQFVTHSISFSARTSANQTQDMIDAKLDKRRK 2040 2050 2060 2070 2080 2090 2310 2320 2330 2340 2350 2360 KIAA14 GVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDIN :.::::::..:.:..::::::: : ::::::::::::::::::::::: .::::.:.:.. gi|163 GIFGPPLGKKFVFMVDDLNMPAKEEYGAQPPIELLRQWMDHGGWYDRKNVGAFKKLIDVT 2100 2110 2120 2130 2140 2150 2370 2380 2390 2400 2410 2420 KIAA14 FVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRER :.::::::::::: .: :: ::::...:.:....:: ::: ::: .: :.. gi|163 FACAMGPPGGGRNPITQRLTRHFNFVAFTELSDTSKATIFSPILGAYL---------RQK 2160 2170 2180 2190 2200 2430 2440 2450 2460 2470 2480 KIAA14 VPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKV .: .. .:.::: :: ::: .::::::: :::::::::::::::::: : ... gi|163 ----EDLASLSTTFVQATIEVYNTITRELLPTPAKVHYTFNLRDLSKVFQGMLMCDIGSL 2210 2220 2230 2240 2250 2490 2500 2510 2520 2530 2540 KIAA14 EDQVQLLRLWYHENCRVFRDRLVNEEDRSWFDQLLKRCME-QWEVTFNKVCPFQPILYGD ... ...::: :: :::::::.:.:::.::..::.::.. ...... : .:.:.:: gi|163 RERDDVIRLWTHECRRVFRDRLINDEDRAWFNDLLSRCVDARFQTNLADCIPSEPLLFGD 2260 2270 2280 2290 2300 2310 2550 2560 2570 2580 2590 2600 KIAA14 FM-SPGSDVKSYELITSESKMMQVIEEYIEDYNQIN-TAKLKLVLFMDAMSHICRISRTL :. . :...:.: . . .:. :.:: ..::: :: :::..::::.::..: :::.: . gi|163 FLDTSGGEAKKYSRLEDPQKIKAVLEEALDDYNTINATAKMNLVLFQDAIGHACRIARII 2320 2330 2340 2350 2360 2370 2610 2620 2630 2640 2650 2660 KIAA14 RQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQ :: ::::: ::::::::.:.::::. :::.::::::::::::..:::.:.: :: ::::. gi|163 RQPLGNALCLGVGGSGRQSMTRLAASMAEFECFQIELSKNYGVAEWREDLKTVLKKAGLE 2380 2390 2400 2410 2420 2430 2670 2680 2690 2700 2710 2720 KIAA14 NLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTK : ..::::::::: :::::::::.:::::.:..: . :.:.:. .:. .: :: ::: gi|163 NQQVVFLFSDTQIKAESFLEDINNILNSGDVPGIYDSAERDEIMVAMKADVQAAGLPPTK 2440 2450 2460 2470 2480 2490 2730 2740 2750 2760 2770 2780 KIAA14 ANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVAT .::..:: .:::.::: :.:::::::.:::::::::.::::::::::. :: :::.::: gi|163 SNLFSAYCNRVRQNIHCVICMSPIGEIFRARLRQFPALVNCCTIDWFSSWPDEALESVAL 2500 2510 2520 2530 2540 2550 2790 2800 2810 2820 2830 2840 KIAA14 VFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFS .:.:..:::... : ..::. :: ..::: ..::.: :.::::: ::: :: :: gi|163 TFMNDLPELNDNAELVRGLVTCCVQLQQSVIGASDDFLARLGRKNYVTPTSYLTLLTIFR 2560 2570 2580 2590 2600 2610 2850 2860 2870 2880 2890 2900 KIAA14 ILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIK :.:.:: .:. . :: .::.::: ....:: .: .: :.:.:.:: ..: :: :: gi|163 KLLGRKKSDLNQQRARMATGLEKLLSAAQEVADLQAELTEMQPMLKEAQRETEATMVQIA 2620 2630 2640 2650 2660 2670 2910 2920 2930 2940 2950 2960 KIAA14 VDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDV .: .:. : ..: :: .:: ::. .: ::::::.::::::::::::..::..:::.:: gi|163 ADKEVAQVTAEQVGKEEAEANVKAQTTQEIADDAQRDLDEALPALDAAVTSLKSLNKGDV 2680 2690 2700 2710 2720 2730 2970 2980 2990 3000 3010 3020 KIAA14 TEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLES :::.::. :: ::.::.:.::::.:.::::: :.::: :::::: . ::.:: .::.: gi|163 TEVKAMSNPPAGVRLVMETVCIMQGVKPKKVAGDKPGQKVDDYWSVSGPLLKDPQKFLDS 2740 2750 2760 2770 2780 2790 3030 3040 3050 3060 3070 3080 KIAA14 LFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEP ::.:::::: . ::. :.:::.::.: ::.: ::::::::::.::::::::: ::: ::: gi|163 LFNFDKDNIPEKVIQKIEPYIENENFTPAAIEKVSKACTSICKWVRAMHKYHHVAKNVEP 2800 2810 2820 2830 2840 2850 3090 3100 3110 3120 3130 3140 KIAA14 KRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQR ::: : ::. :: .:.. :..:: ::.::.: :: :.::. ..::..:: : :.: . gi|163 KRQRLAEAKADLEITMQQLNDAKARLKEVNDRIADMEAKFAAMVAKKKQLEDKAEECGLK 2860 2870 2880 2890 2900 2910 3150 3160 3170 3180 3190 3200 KIAA14 LGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDS : :: ::: :.::::::.:.:: .. ...:. ::....:: :::::::: ..:. . . gi|163 LQRAEKLIFLLGDEKVRWKESVERFDQLIHNVVGDIVISAGTVAYLGPFTEEFRARMCAD 2920 2930 2940 2950 2960 2970 3210 3220 3230 3240 3250 3260 KIAA14 WVKQLRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFID : .: . ::: : . .:..::..:..::.::. :::.:..:: :. . ....:: ::: gi|163 WHGMLAAANVPCTPQASLVSTLSDPLEIRDWQLYGLPKDSMSVANACVVKYAERWPLFID 2980 2990 3000 3010 3020 3030 3270 3280 3290 3300 3310 3320 KIAA14 PQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLL ::.::::::..:: :. : :.::.:::.:::.:::.:::.:::::::::::::::::.:: gi|163 PQGQANKWIREMEADK-LVVMKLTDRDLLRSLENAVRFGSPCLLENVGEELDPALEPILL 3040 3050 3060 3070 3080 3090 3330 3340 3350 3360 3370 3380 KIAA14 KQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLED .::::: :. :.::::.:.:::..:..::::::::: ::::.:::.::.::::::::::: gi|163 RQTYKQAGGLVIKLGDSVVPYHDEFKFYITTKLPNPTYTPEVSTKVTLVNFTLSPSGLED 3100 3110 3120 3130 3140 3150 3390 3400 3410 3420 3430 3440 KIAA14 QLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVL :.:: :::::::::::::. ::..::::.::: ::: .:: :: : :.:::: :::..: gi|163 QMLGLVVAEERPDLEEAKTALIFQNAKMKQELADIEGRILTMLSESTGSPVDDEELINTL 3160 3170 3180 3190 3200 3210 3450 3460 3470 3480 3490 3500 KIAA14 EASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLE .::: :. ::.:::..::.:::::: :: .:.::: :::.::::..:::..:::::::: gi|163 DASKAKSQEISAKVKVAEETEKDIDETRSKYVPVARRTQLLFFCTTDLAHIDPMYQYSLG 3220 3230 3240 3250 3260 3270 3510 3520 3530 3540 3550 3560 KIAA14 WFLNIFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMM :: ..::.:: .: ::.:..:: :::...:.:::..:::::::.:::.:.::::.::.. gi|163 WFRELFLAGIRKSSPADSLEERIHNINEFFTFSLYTSVCRSLFERHKLLFSFLLCARILI 3280 3290 3300 3310 3320 3330 3570 3580 3590 3600 3610 3620 KIAA14 NEGKINQSEWRYLLSGGS-ISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHL ..:::. .:::.:..:.: : . ::: ::.::::... ::.::.: .:. .: .: gi|163 EQGKIDGDEWRFLVAGSSAIPDEAPNPAATWLNDRAWQELRLLSTLPAFEGFAESFGEHA 3340 3350 3360 3370 3380 3390 3630 3640 3650 3660 3670 3680 KIAA14 SEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIE . ::::::: :::.: .: : :: :::.::.:::: ::.. :::.::..: :::: gi|163 AAFRVIFDSAEPHKEDFPEPWATRLDAFQKILVMRCLRFDKLAPMMQDYVANHLGQRFIE 3400 3410 3420 3430 3440 3450 3690 3700 3710 3720 3730 3740 KIAA14 PQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAE :::.:::.:: ::...:::.::::::::::::::::::::::.:::..:::::::::::: gi|163 PQTTNLSMVFPDSSNNTPLVFVLSPGTDPAADLYKFAEEMKFNKKLASISLGQGQGPRAE 3460 3470 3480 3490 3500 3510 3750 3760 3770 3780 3790 3800 KIAA14 AMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSI ::.... ::: :::::::::::::::.::::::.:. ::::.::::::::.:: ::::.. gi|163 AMFHAACERGTWVFFQNCHLAPSWMPTLERLIENIDRDKVHKDFRLWLTSIPSPKFPVAV 3520 3530 3540 3550 3560 3570 3810 3820 3830 3840 3850 3860 KIAA14 LQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKF :::.::::.:::::..::::........:.:. : : ::: ::.::::::: :::::: gi|163 LQNSSKMTVEPPRGIKANLLEAFDGFNDDYLQRCSKEREFKMLLFSLCLFHGVILERRKF 3580 3590 3600 3610 3620 3630 3870 3880 3890 3900 3910 3920 KIAA14 GPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCI : ::::: : .: .:: ::..:: ::::.:: ::::: ::::.::::::::::::::: gi|163 GSLGFNIRYPYTKSDLAICMTQLCMFLDDYDAPPYKVLTYTAGQINYGGRVTDDWDRRCQ 3640 3650 3660 3670 3680 3690 3930 3940 3950 3960 3970 3980 KIAA14 MNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNAN :.::::::::.::. .:..: ::.:.: :: : .:::..:..::.:: :::::::.::: gi|163 MTILEDFYNPNVLKDDHAFSPSGVYQQAAPT-DYEGYLAHIRQLPINDTPEIFGLHENAN 3700 3710 3720 3730 3740 3750 3990 4000 4010 4020 4030 4040 KIAA14 ITFAQNETFALLGTIIQLQPKS--SSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKY :.::..:: .:::... . .:.:...:....:.:...:: . :.:..:. :. . gi|163 IAFANQETSSLLGALLATGGGGGGASGGTSNRDKVIEEVASDILQRCPKPFDLERVQELH 3760 3770 3780 3790 3800 3810 4050 4060 4070 4080 4090 4100 KIAA14 PVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVP :: :::::::::.::.::.:.::... .: :.::::::::::: .:: :: ::. : :: gi|163 PVRYEESMNTVLIQEAIRFNKLLEAMHGSLGDVLKALKGLVVMSEELERMANSLFVNKVP 3820 3830 3840 3850 3860 3870 4110 4120 4130 4140 4150 4160 KIAA14 ELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFA ..::::::::::::..::.::: :..:.:.::..:.::.::::::.:::::::::::::: gi|163 DMWSAKAYPSLKPLAAWVVDLLARVEFIQTWIEEGMPATFWISGFYFPQAFLTGTLQNFA 3880 3890 3900 3910 3920 3930 4170 4180 4190 4200 4210 4220 KIAA14 RKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELY :: :.::::.::::.:. .. ... ::. ::::.::::::::.::: ::::.::::: gi|163 RKHVVSIDTLSFDFQVLKRTHDDIKARPEDGCYIYGLFLEGARYDPEQAALAESRPKELY 3940 3950 3960 3970 3980 3990 4230 4240 4250 4260 4270 4280 KIAA14 TEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHW : : .:: :. .: . .. :.:: :::: :::::::::::::.:. .:.:.. :: :: gi|163 TSMPPLWLRPVSDRPVPQEGVYVCPCYKTLQRAGTLSTTGHSTNFVLPIEVPSKLPQAHW 4000 4010 4020 4030 4040 4050 4290 KIAA14 IKRGVALICALDY :::.::::::::: gi|163 IKRAVALICALDY 4060 4070 4293 residues in 1 query sequences 2693465022 residues in 7827732 library sequences Tcomplib [34.26] (8 proc) start: Wed Mar 4 16:28:06 2009 done: Wed Mar 4 16:36:31 2009 Total Scan time: 4040.740 Total Display time: 13.020 Function used was FASTA [version 34.26.5 April 26, 2007]