hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080909/iprscan-20080909-09420965/chunk_1/iprscan-20080909-09420965.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1410 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF03028.6.ls Dynein heavy chain 1084.3 0 1 PF03028.6.fs Dynein heavy chain 1082.5 0 1 PF08393.3.fs Dynein heavy chain, N-terminal region 2 632.1 5.4e-188 1 PF08393.3.ls Dynein heavy chain, N-terminal region 2 634.1 1.1e-187 1 PF07728.4.fs ATPase family associated with various ce 42.4 4.1e-12 6 PF07728.4.ls ATPase family associated with various ce 35.2 2.1e-07 2 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF08393.3.fs 1/1 1039 1449 .. 1 427 [] 632.1 5.4e-188 PF08393.3.ls 1/1 1039 1449 .. 1 427 [] 634.1 1.1e-187 PF07728.4.ls 1/2 1885 2039 .. 1 184 [] 26.3 1.6e-05 PF07728.4.ls 2/2 2250 2397 .. 1 184 [] 8.9 0.00034 PF03028.6.fs 1/1 3582 4290 .. 1 783 [] 1082.5 0 PF03028.6.ls 1/1 3582 4290 .. 1 783 [] 1084.3 0 Alignments of top-scoring domains: PF08393.3.fs: domain 1 of 1, from 1039 to 1449: score 632.1, E = 5.4e-188 *->peLkqleeElkllkqlWdlysevwesidewketpWsdlRdpekleee ++L+++ +E++++ +lW++ s+++++ ++w++ p s++ d+e+le+ KIAA1410 1039 DKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAI-DAEQLEKN 1084 ldkllkqlrkLpkevrqyea.keafeklkqkiknfkkslpllqeLknpam + + k++ k+ k++++ +a +e++ +++++i++fk ++pl+q L+np+m KIAA1410 1085 VVEAFKTMHKCVKQFKDMPAcQEVALDIRARIEEFKPYIPLIQGLRNPGM 1134 keRHWeqLmqilgvkdfdkknkldsesltLgdlldlnLilkyeeeikdIv + RHWe L+ +++ + + +++ +lt++ l++nL + ++e i +++ KIAA1410 1135 RIRHWETLSNQININ-V-----RPKANLTFARCLEMNL-QDHIESISKVA 1177 dqAqkElaiEkaLkeiketWsnveFelvpYkdtgrckllkGgwdelfekL ++A kE+aiE+aL++++ +Ws++ F++ pYk t+ +++lk + de ++L KIAA1410 1178 EVAGKEYAIEQALDKMEKEWSTILFNVLPYKATD-TYILK-SPDEASQLL 1225 eDnqvlLqsMkaSpyykpFedeiseWekKLslldeileiWleVQrkWvYL +D++v++q+M+ Spy kpFe++i++We+KL l +e+le+Wl++Qr W+YL KIAA1410 1226 DDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYL 1275 EgIFigSeDIrkQLPeEakRFdnIDkeflkiMkkvakdpnVldvcnipgl E+IF +SeDI +QLP+E+kR+++ ++kiMk +++++ V++vc+ ++ KIAA1410 1276 EPIF-SSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRM 1324 leslLerlneqLekcQKaLneYLEtKRlaFPRFYFlSDdDLLEILGnskd l+s L+++n+ L+++QK+L+eYLEtKR+aFPRFYFlSDd+LLEIL+++kd KIAA1410 1325 LDS-LRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKD 1373 PtrvQkHLkKlFdgIasLefdedgkdktIvgmvSkEGEeVpfsnpvsieg Pt+vQ+HL+K+F++Ia+L f+ed +I++m+S EGEeV+++ +++++ KIAA1410 1374 PTAVQPHLRKCFENIARLLFQEDL---EITHMYSAEGEEVQLCFSIYPSS 1420 appVEeWLneLedeMkaTLkellreaveayr<-* +VE+WL+e+e+ Mka++++++++a++ay+ KIAA1410 1421 --NVEDWLREVERSMKASVHDIIEKAIRAYP 1449 PF08393.3.ls: domain 1 of 1, from 1039 to 1449: score 634.1, E = 1.1e-187 *->peLkqleeElkllkqlWdlysevwesidewketpWsdlRdpekleee ++L+++ +E++++ +lW++ s+++++ ++w++ p s++ d+e+le+ KIAA1410 1039 DKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAI-DAEQLEKN 1084 ldkllkqlrkLpkevrqyea.keafeklkqkiknfkkslpllqeLknpam + + k++ k+ k++++ +a +e++ +++++i++fk ++pl+q L+np+m KIAA1410 1085 VVEAFKTMHKCVKQFKDMPAcQEVALDIRARIEEFKPYIPLIQGLRNPGM 1134 keRHWeqLmqilgvkdfdkknkldsesltLgdlldlnLilkyeeeikdIv + RHWe L+ +++ + + +++ +lt++ l++nL + ++e i +++ KIAA1410 1135 RIRHWETLSNQININ-V-----RPKANLTFARCLEMNL-QDHIESISKVA 1177 dqAqkElaiEkaLkeiketWsnveFelvpYkdtgrckllkGgwdelfekL ++A kE+aiE+aL++++ +Ws++ F++ pYk t+ +++lk + de ++L KIAA1410 1178 EVAGKEYAIEQALDKMEKEWSTILFNVLPYKATD-TYILK-SPDEASQLL 1225 eDnqvlLqsMkaSpyykpFedeiseWekKLslldeileiWleVQrkWvYL +D++v++q+M+ Spy kpFe++i++We+KL l +e+le+Wl++Qr W+YL KIAA1410 1226 DDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYL 1275 EgIFigSeDIrkQLPeEakRFdnIDkeflkiMkkvakdpnVldvcnipgl E+IF +SeDI +QLP+E+kR+++ ++kiMk +++++ V++vc+ ++ KIAA1410 1276 EPIF-SSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRM 1324 leslLerlneqLekcQKaLneYLEtKRlaFPRFYFlSDdDLLEILGnskd l+s L+++n+ L+++QK+L+eYLEtKR+aFPRFYFlSDd+LLEIL+++kd KIAA1410 1325 LDS-LRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKD 1373 PtrvQkHLkKlFdgIasLefdedgkdktIvgmvSkEGEeVpfsnpvsieg Pt+vQ+HL+K+F++Ia+L f+ed +I++m+S EGEeV+++ +++++ KIAA1410 1374 PTAVQPHLRKCFENIARLLFQEDL---EITHMYSAEGEEVQLCFSIYPSS 1420 appVEeWLneLedeMkaTLkellreaveayr<-* +VE+WL+e+e+ Mka++++++++a++ay+ KIAA1410 1421 --NVEDWLREVERSMKASVHDIIEKAIRAYP 1449 PF07728.4.ls: domain 1 of 2, from 1885 to 2039: score 26.3, E = 1.6e-05 *->gvlLvGpPGtGKselaerlaealsgqggrpl..........fyvqlt g++LvGp+G+GKs+ + la+a++ +g+p +++ + + yv+++ KIAA1410 1885 GLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSisggmyeavnYYVLNP 1931 rdtteedLlgrrdiapllhGngttswvdgpLvrAaryaretegslpeghi ++ t +L g +d+ t +w+dg++ r a ++ + +++ KIAA1410 1932 KSITMGQLYGEFDLL-------THEWTDGIFSSFIR-AGAITSDTNKKWY 1973 vvlDEinraspevlnaLlslLderrlllpdggelvkvapydklaergree +++ ++ +++ ++++Ld+++ l + ge++k KIAA1410 1974 MFDGPVD---AIWIENMNTVLDDNKKLCLSSGEIIKL------------- 2007 ldlwklgrlihdfrliataNpldgprglnelsaALrrRFlfvtvdpp<-* + + + +++ +l+ +s+A+++R+ +v+++p KIAA1410 2008 ------------TEAMTMMFEVQ---DLAVASPATVSRCGMVYLEPS 2039 PF07728.4.ls: domain 2 of 2, from 2250 to 2397: score 8.9, E = 0.00034 *->gvlLvGpPGtGKs.elaerlaealsgqggrplfyvqltrdtteedLl +vl +Gp+GtGK+ ++++ l++ l ++ +++ t++ + KIAA1410 2250 PVLCIGPTGTGKTlTISDKLLKNLAL--DYISHFLTFSARTSANQTQ 2294 grrdiapllhGngttswvdgpLvrAaryaretegslpeghivvlDEinra +d + +++ g++ + i ++D++n+ KIAA1410 2295 DFID-------SKLDKRRKGVFGPPLG----------RNFIFFIDDLNMP 2327 spevlnaLlslLderrlllpdggelvkvapydklaerg.reeldlwklgr e+ +a ++++ r +++ gg++ ++ +++++++ + d KIAA1410 2328 ALETYGAQ-PPIELLRQWMDHGGWYDRK-----IIGAFkNLV-D------ 2364 lihdfrliataNpldgprglnelsaALrrRFlfvtvdpp<-* ++++ +++p++ +g+n + + L r F++ ++ + KIAA1410 2365 ----INFVCAMGPPG--GGRNTVTPRLMRHFNYLSFAEM 2397 PF03028.6.fs: domain 1 of 1, from 3582 to 4290: score 1082.5, E = 0 *->lentypnpkvdwlsdqqWdsiarLseleeFrgLdddleknapdkrWk ++ +np++dwlsd +W +i +Ls+l++F+++ d+ k+ +++ KIAA1410 3582 ISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHL--SEFR 3626 kwydseqPgEeeklPkeWkdeqklsidslkksaFqKLlllRalRPDRlty ++ds++P + e+lP+ W+ + + +FqKLl+lR+lR D++t+ KIAA1410 3627 VIFDSLEP-HREPLPGIWD---------QYLDQFQKLLVLRCLRGDKVTN 3666 alrnFveekLpGekfvepdppldlskiyekeSspstPilFiLSPGaDPsk a+++Fv+++L + +f+ep ++ +ls +++ +S+++tP++F+LSPG DP++ KIAA1410 3667 AMQDFVATNL-EPRFIEP-QTANLSVVFK-DSNSTTPLIFVLSPGTDPAA 3713 dvekLAkkmGFtfdnGkklhSiSLGQGQgpniAekaIetAaksGhWVlLQ d+ k+A++m+F+ kkl iSLGQGQgp Ae++++ + ++G WV+ Q KIAA1410 3714 DLYKFAEEMKFS----KKLSAISLGQGQGP-RAEAMMRSSIERGKWVFFQ 3758 NiHLaasWLptLEKkLesltppegtHpdFRLFLTaEpaprPeehIfPigl N+HLa+sW+p LE + e + p+++H dFRL+LT+ p+ + fP+++ KIAA1410 3759 NCHLAPSWMPALERLIEHIN-PDKVHRDFRLWLTSLPSNK-----FPVSI 3802 LqnSiKiTNEPPtGlKANLlraysnDPIfdqeflemckkpaefkrllFlL Lqn+ K+T EPP+G++ANLl++ys+ + ++fl +c k +efk+ll +L KIAA1410 3803 LQNGSKMTIEPPRGVRANLLKSYSS---LGEDFLNSCHKVMEFKSLLLSL 3849 CfFHAVVqERRkFGPlGWNksYEFNesDLriSvdvldnyLeanakGRqNi C FH +ERRkFGPlG N++YEF ++DLri+ ++l ++L+++ KIAA1410 3850 CLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEY------- 3892 dpdkvPWeaLRYlfGeimYGGrItDdwDrRLLrtyLeefftpelfdgnad d +P+ L+Y Gei+YGGr+tDdwDrR+ + +Le f++p ++ + + KIAA1410 3893 --DDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSP--E 3938 yeLapkidgdlgfavPpntdyeeYieyIeesLPsessPelfGLhpNAEIg +++ ++++ ++Pp+ d +Y+ yI+ LP + Pe+fGLh NA+I+ KIAA1410 3939 HSYSA---SGIYHQIPPTYDLHGYLSYIKS-LPLNDMPEIFGLHDNANIT 3984 fltqeteklirtllelQpreaggeldggsgekvsrkkdssEEvvkqvlrd f ++et l+ t+++lQp++++ +g++g r EE+v++v + KIAA1410 3985 FAQNETFALLGTIIQLQPKSSS---AGSQG----R-----EEIVEDVTQN 4022 ileklpkklCqklFdkeelmlkrteeikdPlfvVlvQEiermNkLlkeir il k+p +++++ +m+k+++ +++++++VlvQE++r N Ll++i+ KIAA1410 4023 ILLKVP-----EPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVIT 4067 rSLkeLdlglkGeltmsndlEeliksLlngrVPaWDmWakksyPslkpLg ++L++L ++lkG+++ms++lE + sL+n+ VP+ W +k+yPslkpL KIAA1410 4068 QTLQDLLKALKGLVVMSSQLELMAASLYNNTVPE--LWSAKAYPSLKPLS 4115 sWvtDLlkRirQLqeWtedsGGAklglPkvvWLsGFFnPQsFLTAimQsv sWv DLl+R+++Lq W++d g+P v+W+sGFF+PQ+FLT++ Q++ KIAA1410 4116 SWVMDLLQRLDFLQAWIQD------GIPAVFWISGFFFPQAFLTGTLQNF 4159 ARknkwPLDkLcLdteVtkkekeeqdskepPedGvyVhGLfLEGArWDsk ARk ++++D + +d++V+ +e ++++ + P G+y+hGLfLEGArWD + KIAA1410 4160 ARKFVISIDTISFDFKVM-FEAPSELTQR-PQVGCYIHGLFLEGARWDPE 4207 tgllaeskpKeLfspmPViwlkavpasdkqetkdvyecPVYktkaRggvL +++laes pKeL+ +m Viwl ++p k ++d y cP Ykt +R g+L KIAA1410 4208 AFQLAESQPKELYTEMAVIWLLPTPN-RKAQDQDFYLCPIYKTLTRAGTL 4256 STTGHStnyvftfnLktkedtpaskWilaGVALllq<-* STTGHStnyv++++++t++ p+++Wi +GVAL++ KIAA1410 4257 STTGHSTNYVIAVEIPTHQ--PQRHWIKRGVALICA 4290 PF03028.6.ls: domain 1 of 1, from 3582 to 4290: score 1084.3, E = 0 *->lentypnpkvdwlsdqqWdsiarLseleeFrgLdddleknapdkrWk ++ +np++dwlsd +W +i +Ls+l++F+++ d+ k+ +++ KIAA1410 3582 ISIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHL--SEFR 3626 kwydseqPgEeeklPkeWkdeqklsidslkksaFqKLlllRalRPDRlty ++ds++P + e+lP+ W+ + + +FqKLl+lR+lR D++t+ KIAA1410 3627 VIFDSLEP-HREPLPGIWD---------QYLDQFQKLLVLRCLRGDKVTN 3666 alrnFveekLpGekfvepdppldlskiyekeSspstPilFiLSPGaDPsk a+++Fv+++L + +f+ep ++ +ls +++ +S+++tP++F+LSPG DP++ KIAA1410 3667 AMQDFVATNL-EPRFIEP-QTANLSVVFK-DSNSTTPLIFVLSPGTDPAA 3713 dvekLAkkmGFtfdnGkklhSiSLGQGQgpniAekaIetAaksGhWVlLQ d+ k+A++m+F+ kkl iSLGQGQgp Ae++++ + ++G WV+ Q KIAA1410 3714 DLYKFAEEMKFS----KKLSAISLGQGQGP-RAEAMMRSSIERGKWVFFQ 3758 NiHLaasWLptLEKkLesltppegtHpdFRLFLTaEpaprPeehIfPigl N+HLa+sW+p LE + e + p+++H dFRL+LT+ p+ + fP+++ KIAA1410 3759 NCHLAPSWMPALERLIEHIN-PDKVHRDFRLWLTSLPSNK-----FPVSI 3802 LqnSiKiTNEPPtGlKANLlraysnDPIfdqeflemckkpaefkrllFlL Lqn+ K+T EPP+G++ANLl++ys+ + ++fl +c k +efk+ll +L KIAA1410 3803 LQNGSKMTIEPPRGVRANLLKSYSS---LGEDFLNSCHKVMEFKSLLLSL 3849 CfFHAVVqERRkFGPlGWNksYEFNesDLriSvdvldnyLeanakGRqNi C FH +ERRkFGPlG N++YEF ++DLri+ ++l ++L+++ KIAA1410 3850 CLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEY------- 3892 dpdkvPWeaLRYlfGeimYGGrItDdwDrRLLrtyLeefftpelfdgnad d +P+ L+Y Gei+YGGr+tDdwDrR+ + +Le f++p ++ + + KIAA1410 3893 --DDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSP--E 3938 yeLapkidgdlgfavPpntdyeeYieyIeesLPsessPelfGLhpNAEIg +++ ++++ ++Pp+ d +Y+ yI+ LP + Pe+fGLh NA+I+ KIAA1410 3939 HSYSA---SGIYHQIPPTYDLHGYLSYIKS-LPLNDMPEIFGLHDNANIT 3984 fltqeteklirtllelQpreaggeldggsgekvsrkkdssEEvvkqvlrd f ++et l+ t+++lQp++++ +g++g r EE+v++v + KIAA1410 3985 FAQNETFALLGTIIQLQPKSSS---AGSQG----R-----EEIVEDVTQN 4022 ileklpkklCqklFdkeelmlkrteeikdPlfvVlvQEiermNkLlkeir il k+p +++++ +m+k+++ +++++++VlvQE++r N Ll++i+ KIAA1410 4023 ILLKVP-----EPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVIT 4067 rSLkeLdlglkGeltmsndlEeliksLlngrVPaWDmWakksyPslkpLg ++L++L ++lkG+++ms++lE + sL+n+ VP+ W +k+yPslkpL KIAA1410 4068 QTLQDLLKALKGLVVMSSQLELMAASLYNNTVPE--LWSAKAYPSLKPLS 4115 sWvtDLlkRirQLqeWtedsGGAklglPkvvWLsGFFnPQsFLTAimQsv sWv DLl+R+++Lq W++d g+P v+W+sGFF+PQ+FLT++ Q++ KIAA1410 4116 SWVMDLLQRLDFLQAWIQD------GIPAVFWISGFFFPQAFLTGTLQNF 4159 ARknkwPLDkLcLdteVtkkekeeqdskepPedGvyVhGLfLEGArWDsk ARk ++++D + +d++V+ +e ++++ + P G+y+hGLfLEGArWD + KIAA1410 4160 ARKFVISIDTISFDFKVM-FEAPSELTQR-PQVGCYIHGLFLEGARWDPE 4207 tgllaeskpKeLfspmPViwlkavpasdkqetkdvyecPVYktkaRggvL +++laes pKeL+ +m Viwl ++p k ++d y cP Ykt +R g+L KIAA1410 4208 AFQLAESQPKELYTEMAVIWLLPTPN-RKAQDQDFYLCPIYKTLTRAGTL 4256 STTGHStnyvftfnLktkedtpaskWilaGVALllq<-* STTGHStnyv++++++t++ p+++Wi +GVAL++ KIAA1410 4257 STTGHSTNYVIAVEIPTHQ--PQRHWIKRGVALICA 4290 //