hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-00494154/chunk_1/iprscan-20080502-00494154.nocrc
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Query sequence: KIAA1366
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
PF00135.18.fs Carboxylesterase                             331.9    9.9e-97   1
PF00135.18.ls Carboxylesterase                             -16.8    6.5e-12   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
PF00135.18.fs   1/1       1   316 [.   261   592 .]   331.9  9.9e-97
PF00135.18.ls   1/1       1   316 [.     1   592 []   -16.8  6.5e-12

Alignments of top-scoring domains:
PF00135.18.fs: domain 1 of 1, from 1 to 316: score 331.9, E = 9.9e-97
                   *->rAIlqSGsalspwaitsppearnrakrlAkllGCpgedseelveCLR
                      +AI qSG+a s+w+++++p  +++++ lA ++GC+ eds+e veCLR
    KIAA1366     1    KAIAQSGTAISSWSVNYQP--LKYTRLLAAKVGCDREDSAEAVECLR 45   

                   kksaeelldaqwklllleefgffplfpFgPVvdGdtpdaflpkdPeellk
                   +k+ +el+d++   +++++   f      PVvdGd    ++p+dPe+l++
    KIAA1366    46 RKPSRELVDQDV--QPARYHIAFG-----PVVDGD----VVPDDPEILMQ 84   

                   egnfnkvPlliGvtsdEGllflayvl.dp.lsadllseidnedlflellp
                   +g+f ++++liGv++ EGl f+    + ++ +    s + +++   +++ 
    KIAA1366    85 QGEFLNYDMLIGVNQGEGLKFVEDSAeSEdGV----SASAFDF-TVSNFV 129  

                   ellpgase.steklreeiadaikeeYtdd.ddnseesrrdalldllsDyl
                   ++l+g++e++     + ++++ik++Ytd+ d+++ e+rr+ ll l++D++
    KIAA1366   130 DNLYGYPEgK-----DVLRETIKFMYTDWaDRDNGEMRRKTLLALFTDHQ 174  

                   FvcPilrlalaraakagspvYlYrFdyrssdsfnqyrinllwppwrgvsH
                   +v+P +++ ++ +a+++spvY+Y F +++         ++ +p+w  + H
    KIAA1366   175 WVAP-AVATAKLHADYQSPVYFYTFYHHCQ--------AEGRPEWADAAH 215  

                   gdelsYvFGnpls.k.ly....sseeeemlssrrmmrywtnFAktGnPN.
                   gdel+YvFG+p+++ ++  + ++s+ ++mls +++m+ywtnFAktG+PN+
    KIAA1366   216 GDELPYVFGVPMVgAtDLfpcnFSKNDVMLS-AVVMTYWTNFAKTGDPNq 264  

                   ............ngessglvkWppytkeeqkyylpitllnitqk.lreed
                   + +++++  +++++  +++v+W +++++e + yl+i+l++++++++r+++
    KIAA1366   265 pvpqdtkfihtkPNR-FEEVVWSKFNSKEKQ-YLHIGLKPRVRDnYRANK 312  

                   Prkvkcafw<-*
                        +afw   
    KIAA1366   313 -----VAFW    316  

PF00135.18.ls: domain 1 of 1, from 1 to 316: score -16.8, E = 6.5e-12
                   *->mllllllllllllflavvataptspedpvVeTsyvgGkvrGlrvkvd
                                                                     
    KIAA1366     -    ----------------------------------------------- -    

                   ggnkpvyaFlGIPYAkPPvGeLRFkkPqPpepWtgvldATkygpaCpQnd
                                                                     
    KIAA1366     - -------------------------------------------------- -    

                   lgfpgfslalhvgsemwnkntgksmSEDCLYLNVytPklasenkklPVmV
                                                             +       
    KIAA1366     1 ------------------------------------------K------- 1    

                   wIHGGGFqsGsassvslddydgpdlaasedVVVVtiNYRLGalGFLstgd
                                                                     
    KIAA1366     - -------------------------------------------------- -    

                   selppppGNaGLlDQvlALrWVqeNIaaFGGDPdnVTlFGeSAGAaSVsl
                                                                     
    KIAA1366     - -------------------------------------------------- -    

                   lllSppqsrGLFhrAIlqSGsalspwaitsppearnrakrlAkllGCpge
                                 AI qSG+a s+w+++++p  +++++ lA ++GC+ e
    KIAA1366     2 --------------AIAQSGTAISSWSVNYQP--LKYTRLLAAKVGCDRE 35   

                   dseelveCLRkksaeelldaqwklllleefgffplfpFgPVvdGdtpdaf
                   ds+e veCLR+k+ +el+d++   +++++   f      PVvdGd    +
    KIAA1366    36 DSAEAVECLRRKPSRELVDQDV--QPARYHIAFG-----PVVDGD----V 74   

                   lpkdPeellkegnfnkvPlliGvtsdEGllflayvl.dp.lsadllseid
                   +p+dPe+l+++g+f ++++liGv++ EGl f+    + ++ +    s + 
    KIAA1366    75 VPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAeSEdGV----SASA 120  

                   nedlflellpellpgase.steklreeiadaikeeYtdd.ddnseesrrd
                   +++   +++ ++l+g++e++     + ++++ik++Ytd+ d+++ e+rr+
    KIAA1366   121 FDF-TVSNFVDNLYGYPEgK-----DVLRETIKFMYTDWaDRDNGEMRRK 164  

                   alldllsDylFvcPilrlalaraakagspvYlYrFdyrssdsfnqyrinl
                    ll l++D+++v+P +++ ++ +a+++spvY+Y F +++         ++
    KIAA1366   165 TLLALFTDHQWVAP-AVATAKLHADYQSPVYFYTFYHHCQ--------AE 205  

                   lwppwrgvsHgdelsYvFGnpls.k.ly....sseeeemlssrrmmrywt
                    +p+w  + Hgdel+YvFG+p+++ ++  + ++s+ ++mls +++m+ywt
    KIAA1366   206 GRPEWADAAHGDELPYVFGVPMVgAtDLfpcnFSKNDVMLS-AVVMTYWT 254  

                   nFAktGnPN.............ngessglvkWppytkeeqkyylpitlln
                   nFAktG+PN++ +++++  +++++  +++v+W +++++e + yl+i+l++
    KIAA1366   255 NFAKTGDPNqpvpqdtkfihtkPNR-FEEVVWSKFNSKEKQ-YLHIGLKP 302  

                   itqk.lreedPrkvkcafw<-*
                   ++++++r+++     +afw   
    KIAA1366   303 RVRDnYRANK-----VAFW    316  

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