hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-00012781/chunk_1/iprscan-20080502-00012781.nocrc
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Query sequence: KIAA1337
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF02460.9.ls Patched family                                -435.2      0.004   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF02460.9.ls   1/1     285  1392 ..     1   975 []  -435.2    0.004

Alignments of top-scoring domains:
PF02460.9.ls: domain 1 of 1, from 285 to 1392: score -435.2, E = 0.004
                   *->llsldivytrtpdDirksltergarsedeplkenkFfpgkskpearf
                       + + +   r   +++++ ++r+  s +     +         ++++
    KIAA1337   285    HAAVAANQSRARRGASRWDYSRAYVSANTQTHAH---------WRIE 322  

                   vnliitAkdrnsedytrpNiLnpkyLnevvqvndyiltnveipddgnkki
                     li+ A +         Ni     L  +  ++ +i+   +  ++   k 
    KIAA1337   323 --LIFLARGDAE-----RNIFTSERLVTIHEIERKIMDHPGFREFC-WKP 364  

                   setykdlCs.ryCdlncpvnkhyngLdtKtRWGnFGPfaeLlsrrhnvdk
                    e  kdl +++y ++  p+   + +  t                  +   
    KIAA1337   365 HEVLKDLPLgSYSYCSPPSSLMTYFFPT------------------E--- 393  

                   srikltYPtm..kvlgtpiYlgphfgGVkvdpsendvekllDsltklklv
                   ++ k+ Y  m++++ +  ++l      ++++                  v
    KIAA1337   394 RGGKIYYDGMgqDLADIRGSLELAMTHPEFYW----------------YV 427  

                   dtksetgnissa..KaivLq......yrlkfdeeeveeyske..wEdsLf
                   d     +n++s+  ++  L++ + ++y +  d+ + e+ +k++++  + +
    KIAA1337   428 DEGLSADNLKSSllRSEILFgaplpnYYSV-DDRWEEQRAKFqsFVVTYV 476  

                   dylenkyaseehiqitifsdsyledElvr..naltlvPffvvgfaiLltF
                   ++l ++++s+  +q+++      + E++r+ n + l+ f++ ++++ l++
    KIAA1337   477 AMLAKQSTSK--VQVLYGGTDLFDYEVRRtfNNDMLLAFISSSCIAALVY 524  

                   siitsvKWtlssdrsgslmiDWvssKpiLAilGclsPllAivsafGlL..
                   ++ +++                    + L+  G++s +l+++ a+ +L +
    KIAA1337   525 ILTSCS--------------------VFLSFFGIASIGLSCLVAL-FLyh 553  

                   fwfGfpFnsIvc.VmPFLvLGAIGVDDmFlmvaaWqrttkslsetaRkek
                     fG  +  I+++V+ F + G IGVDD+F+ ++  ++ t  ++       
    KIAA1337   554 VVFGIQYLGILNgVAAFVIVG-IGVDDVFVFINTYRQATHLED------- 595  

                   vnvEvkkRmgetlsEaGpsItITSlTnvlsFgiGiiTptPaIqlFClyta
                       +  Rm+ t   aG + + TSlT +++ ++  ++ +Pa+  F l+ +
    KIAA1337   596 ----PQLRMIHTVQTAGKATFFTSLTTAAAYAANVFSQIPAVHDFGLFMS 641  

                   vAvfFdFiYQiTFfaAvmaivakrEmkgrhvlfvrRtFkaVdiakeesps
                   + v  +++  +    A++ +   + +  + +++                 
    KIAA1337   642 LIVSCCWLAVLVTMPAALGLWSLYLAPLESSCQTS-------CH------ 678  

                   kLWLLGvardiqrissessrpvAPveklkkkkSkfrkDadae........
                              q +s+ +s               f  D  a +++ ++++
    KIAA1337   679 -----------QNCSRKTSLH-------------FPGDVFATpeqvggsp 704  

                   ..................................................
                    +++ +  +++ +  + ++++ + + ++ +  + ++++ ++ ++++++++
    KIAA1337   705 aqgpipyldddiplleveeepvslelgdvslvsvspeglqpasntgsrgh 754  

                   ..................................................
                      + ++  ++    +  +++    +   +    +    ++ ++ ++ + 
    KIAA1337   755 livqlqellhhwvlwsavksrwvivglfvsililslvfasrlrpasrapl 804  

                   ..................................................
                     +++++ +   + + + + ++ +  + ++  ++++++ +++ +++ +++
    KIAA1337   805 lfrpdtniqvlldlkynlsaegiscitcsglfqekphslqnnirtslekk 854  

                   ..................................................
                   +++++ +  ++++ + ++ +++   ++ ++++++   + + + + + + +
    KIAA1337   855 rrgsgvpwasrpeatlqdfpgtvyiskvksqghpavyrlslnaslpapwq 904  

                   ..................................................
                     ++++++ ++ +  + + ++ +++ +   ++ +  +  +++++   ++ 
    KIAA1337   905 avspgdgevpsfqvyrapfgnftkkltacmstvgllqaaspsrkwmlttl 954  

                   ..................................................
                     + +++ + + +    +++++++++    ++++++ +++    +++   
    KIAA1337   955 acdakrgwkfdfsfyvatkeqqhtrklyfaqshkppfhgrvcmappgcll 1004 

                   sdKktiieEvaekaekssedsdssksheaeqKdltsRGAmGrffleiYcp
                   s+                          +++  +t       ff   ++p
    KIAA1337  1005 SS--------------------------SPD-GPTK-----GFF---FVP 1019 

                   Fllnpkvrlcvllvf..vvYlaiaiYGcvnikegLdPdkLvveDSpLvei
                     + pk rl++ + f+++v    +  G    ++  d++  v   + ++ +
    KIAA1337  1020 SEKVPKARLSATFGFnpCV---NTGCGKPAVRPLVDTGAMVFVVFGIIGV 1066 

                   lklrekffwpeGqqvqVfVnNPPdLtiNpenrdrlnemvneFEstpyslG
                   ++ r      +G+++ V+     dL++   +   l  +  + ++ ++   
    KIAA1337  1067 NRTRQVDNHVIGDPGSVVYDSSFDLFK---EIGHLCHLCKAIAANSELVK 1113 

                   kGWGEnsTkfWLreYenFlktSelemseeedeekaidddknvsvvvkdkl
                   +     + +     Y      S l+m+  e  e                 
    KIAA1337  1114 P----GGAQCLPSGYSI-S--SFLQMLHPECKE----------------- 1139 

                   ewpsydelewfLkwpgnslqWagdlvwdnpnksdkettelkkFrFttaYH
                    +   ++l+  L  +  +  ++g ++w      +++tt   k  F+t   
    KIAA1337  1140 LP-EPNLLPGQLSHGAVGV-REGRVQWI--SMAFESTTYKGKSSFQTY-- 1183 

                   gkdlstw....tdRtkllke...wR...svADeypeKFNVtvFdedspfl
                    +d+  w++  +++  +l e++ +R++ ++   +++     +F+e     
    KIAA1337  1184 -SDYLRWesflQQQLQALPEgsvLRrgfQTCEHWKQ-----IFME----- 1222 

                   DqlltilpttiqsiiialicMavVcflFIpnpitvfvitlaiaSIdiGVf
                     +  +++++ + +++ lic a+V+ +F  ++  ++ + l+i+ I   V+
    KIAA1337  1223 --IVGVQSALCGLVLSLLICVAAVA-VFTTHILLLLPVLLSILGIVCLVV 1269 

                   GfLSlWGVdLDPIsMitiIMSIGFSVDfsAHIaYhfyrsrgsesqstpde
                    ++ + G    ++  i++ +  G SVD+  H   ++  +++++++  + +
    KIAA1337  1270 TIMYWSGWEMGAVEAISLSILVGSSVDYCVHLVEGYLLAGENLPPHQAED 1319 

                   .......RvadALealGWPvfqaalSTiLcvlvLlfVdsYmvvvFf...K
                    +++++ R  +A   +G  ++  al T+++ ++L+f    ++  F++ +K
    KIAA1337  1320 artqrqwRTLEAVRHVGVAIVSSALTTVIATVPLFFC---IIAPFAkfgK 1366 

                   TvvLVvvlGllHGLifLPiiLslfvt<-*
                    v L ++ ++l  L +  ++L + ++   
    KIAA1337  1367 IVALNTGVSILYTLTVSTALLGIMAP    1392 

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