# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/fh14327.fasta.huge -Q ../query/KIAA1325.ptfa ./tmplib.24314 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 KIAA1325, 354 aa
 vs ./tmplib.24314 library

1987151 residues in  2037 sequences
  Expectation_n fit: rho(ln(x))= 3.1083+/-0.00449; mu= 21.9951+/- 0.309
 mean_var=70.2726+/-16.480, 0's: 0 Z-trim: 4  B-trim: 135 in 1/39
 Lambda= 0.152996

FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 37, opt: 25, open/ext: -10/-2, width:  16
The best scores are:                                      opt bits E(2037)
KIAA0746  ( 1029 res)   hk04140                    (1029)  167 46.6 7.2e-06
KIAA0141  ( 536 res)   ha03721                     ( 536)  138 39.7 0.00044


>>KIAA0746  ( 1029 res)   hk04140                         (1029 aa)
 initn:  90 init1:  90 opt: 167  Z-score: 197.3  bits: 46.6 E(): 7.2e-06
Smith-Waterman score: 167;  23.881% identity (55.597% similar) in 268 aa overlap (67-317:473-730)

         40        50        60        70        80        90      
KIAA13 WKKEKTDYTHANLVDKALQLLKERILKGDTLAYFLRGQLYFEEGWYEEALEQFEEIKEKD
                                     :: : .  :   .   .  : ..   . ..
KIAA07 SSIDGLHQISSIVPFLTDSSCCGYHKASYYLAVFYETGLNVPRDQLQGMLYSLVGGQGSE
            450       460       470       480       490       500  

        100       110        120       130        140       150    
KIAA13 HQATYQLGVMYYDGLGT-TLDAEKGVDYMKKILDSPCPKARH-LKFAAAYNLGRAYYEGK
       . ....::  .:.:. .  :: : .  :...:  .  :  .: :.   ::       . .
KIAA07 RLSSMNLGYKHYQGIDNYPLDWELSYAYYSNIA-TKTPLDQHTLQGDQAYVETIRLKDDE
            510       520       530        540       550       560 

           160         170       180         190       200         
KIAA13 GVK-RSNEEAER-LWLI-AADNGNPKASVKAQSML--GLYYSTKEPKELEKAFYWHSEAC
        .: ...:...  .::   :  ::  :. .  .::  :    .:.:   : :. :...  
KIAA07 ILKVQTKEDGDVFMWLKHEATRGNAAAQQRLAQMLFWGQQGVAKNP---EAAIEWYAK--
             570       580       590       600          610        

     210       220             230       240       250       260   
KIAA13 GNGNLESQGALGLMYLY------GQGIRQDTEAALQCLREAAERGNVYAQGNLVEYYYKM
         : ::..   .:.: :      :::.... . ::. ...:: .:   : ..:  ::.:.
KIAA07 --GALETEDP-ALIYDYAIVLFKGQGVKKNRRLALELMKKAASKGLHQAVNGLGWYYHKF
          620        630       640       650       660       670   

            270          280       290       300       310         
KIAA13 KF-FTKCVAF---SKRIADYDEVHDIPMIAQVTDCLPEFIGRGMAMASFYHARCLQLGLG
       :  ..: . .   ...... :  ... .. ..   .:   ::....:. :  .  : :  
KIAA07 KKNYAKAAKYWLKAEEMGNPDASYNLGVL-HLDGIFPGVPGRNQTLAGEYFHKAAQGGHM
           680       690       700        710       720       730  

     320       330       340       350                             
KIAA13 ITRDETTAKHYYSKACRLNPALADELHSLLIRQRI                         
                                                                   
KIAA07 EGTLWCSLYYITGNLETFPRDPEKAVVWAKHVAEKNGYLGHVIRKGLNAYLEGSWHEALL
            740       750       760       770       780       790  

>>KIAA0141  ( 536 res)   ha03721                          (536 aa)
 initn: 129 init1: 129 opt: 138  Z-score: 165.1  bits: 39.7 E(): 0.00044
Smith-Waterman score: 183;  24.686% identity (53.975% similar) in 239 aa overlap (22-256:223-448)

                        10        20        30        40        50 
KIAA13          NTHCRKRMKLTSEKLPKNPFYASVSQYAAKNQKFFQWKKEKTDYTHANLVD
                                     .:. . :   :     .::. : ...  ..
KIAA01 RNFSHNSLRGARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQ-DKSKTLSLE
            200       210       220       230       240        250 

              60        70        80        90        100       110
KIAA13 KALQLLKERILKGDTLAYFLRGQLYFEEGWYEEALEQFEEIKEKDH-QATYQLGVMYYDG
       .:.  ... .  . ..:. . :   .. : .  :.  :..   . . .: :. :. .  :
KIAA01 EAVTSIQQLFQLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHG
             260       270       280       290       300       310 

              120       130       140       150       160          
KIAA13 LGTTLDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLI-
        ::  :  :.: :..         : . .  : :  .:   .  . . . :. . . :. 
KIAA01 RGTPRDISKAVLYYQLA-------ASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLK
             320              330       340       350       360    

      170       180       190        200       210       220       
KIAA13 -AADNGNPKASVKAQSMLGLYYSTKEPK-ELEKAFYWHSEACGNGNLESQGALGLMYLYG
        :::.:      .::..::. . ::::  . ..:  .   : .::. .:.  ::. :  :
KIAA01 QAADSG----LREAQAFLGVLF-TKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKG
          370           380        390       400       410         

       230       240       250       260       270       280       
KIAA13 QGIRQDTEAALQCLREAAERGNVYAQGNLVEYYYKMKFFTKCVAFSKRIADYDEVHDIPM
        :....   ::.: ...:  ::  ::  :                               
KIAA01 LGVQRNLGEALRCYQQSAALGNEAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCS
     420       430       440       450       460       470         




354 residues in 1 query   sequences
1987151 residues in 2037 library sequences
 Scomplib [34.26]
 start: Thu Dec 18 15:17:50 2008 done: Thu Dec 18 15:17:51 2008
 Total Scan time:  0.360 Total Display time:  0.020

Function used was FASTA [version 34.26.5 April 26, 2007]