# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/hh15990.fasta.nr -Q ../query/KIAA1262.ptfa /cdna2/lib/nr/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
KIAA1262, 1362 aa
vs /cdna2/lib/nr/nr library
2693465022 residues in 7827732 sequences
statistics sampled from 60000 to 7818321 sequences
Expectation_n fit: rho(ln(x))= 6.0477+/-0.000195; mu= 10.6033+/- 0.011
mean_var=106.4540+/-20.803, 0's: 41 Z-trim: 84 B-trim: 507 in 2/64
Lambda= 0.124306
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 40, opt: 28, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7827732)
gi|119568121|gb|EAW47736.1| spectrin repeat contai (5509) 8679 1568.9 0
gi|24417709|gb|AAN60442.1| nesprin-1 [Homo sapiens (8797) 8628 1559.9 0
gi|119568116|gb|EAW47731.1| spectrin repeat contai (8749) 8624 1559.2 0
gi|119568112|gb|EAW47727.1| spectrin repeat contai (8757) 8624 1559.2 0
gi|119568122|gb|EAW47737.1| spectrin repeat contai (8779) 8624 1559.2 0
gi|119568124|gb|EAW47739.1| spectrin repeat contai (8797) 8624 1559.2 0
gi|22597198|gb|AAN03486.1| enaptin [Homo sapiens] (8749) 8621 1558.7 0
gi|220675498|emb|CAX11912.1| spectrin repeat conta (8749) 8621 1558.7 0
gi|29839561|sp|Q8NF91.2|SYNE1_HUMAN RecName: Full= (8797) 8621 1558.7 0
gi|154277116|ref|NP_892006.2| spectrin repeat cont (8797) 8621 1558.7 0
gi|220675499|emb|CAX11913.1| spectrin repeat conta (8797) 8621 1558.7 0
gi|114609846|ref|XP_001139525.1| PREDICTED: nespri (8749) 8570 1549.5 0
gi|114609848|ref|XP_001138443.1| PREDICTED: nespri (8797) 8570 1549.5 0
gi|73946144|ref|XP_541154.2| PREDICTED: similar to (8760) 7949 1438.1 0
gi|149744149|ref|XP_001494325.1| PREDICTED: simila (8798) 7830 1416.8 0
gi|71480173|ref|NP_001025080.1| spectrin repeat co (8026) 7123 1290.0 0
gi|148671629|gb|EDL03576.1| mCG14633 [Mus musculus (1375) 7085 1282.5 0
gi|149038518|gb|EDL92848.1| rCG41130 [Rattus norve (1333) 7076 1280.9 0
gi|126311206|ref|XP_001381250.1| PREDICTED: simila (8794) 7023 1272.1 0
gi|118088392|ref|XP_419679.2| PREDICTED: similar t (8794) 6328 1147.4 0
gi|109072363|ref|XP_001100435.1| PREDICTED: simila (3347) 5849 1061.2 0
gi|189530625|ref|XP_001920330.1| PREDICTED: simila (8621) 4637 844.2 0
gi|47221249|emb|CAG13185.1| unnamed protein produc (6015) 3574 653.4 1.3e-183
gi|34849883|tpg|DAA01060.1| TPA: TPA_exp: spectrin (8407) 3455 632.2 4.4e-177
gi|32141360|gb|AAP74645.1| synaptic nuclear envelo (1594) 3352 613.1 4.6e-172
gi|189533134|ref|XP_698040.3| PREDICTED: similar t (8363) 3077 564.4 1.1e-156
gi|94734023|emb|CAH68877.2| novel protein similar (8130) 3075 564.0 1.4e-156
gi|47224613|emb|CAG03597.1| unnamed protein produc (8348) 2022 375.2 1e-99
gi|94732095|emb|CAI12049.2| novel protein similar (7319) 1974 366.5 3.6e-97
gi|198431763|ref|XP_002124429.1| PREDICTED: simila (8041) 1664 311.0 2.1e-80
gi|210122241|gb|EEA69949.1| hypothetical protein B (8539) 1457 273.9 3.3e-69
gi|194225084|ref|XP_001916097.1| PREDICTED: spectr (6871) 933 179.8 5.4e-41
gi|73963167|ref|XP_547851.2| PREDICTED: similar to (6880) 933 179.8 5.4e-41
gi|114653464|ref|XP_001169405.1| PREDICTED: spectr (6861) 881 170.5 3.5e-38
gi|114653460|ref|XP_001170042.1| PREDICTED: spectr (6885) 881 170.5 3.5e-38
gi|24417711|gb|AAN60443.1| nesprin-2 [Homo sapiens (6884) 876 169.6 6.4e-38
gi|116242809|sp|Q8WXH0.3|SYNE2_HUMAN RecName: Full (6885) 876 169.6 6.4e-38
gi|118918407|ref|NP_878918.2| spectrin repeat cont (6907) 876 169.6 6.5e-38
gi|119601249|gb|EAW80843.1| spectrin repeat contai (6884) 874 169.2 8.3e-38
gi|119601248|gb|EAW80842.1| spectrin repeat contai (6885) 874 169.2 8.3e-38
gi|17016967|gb|AAL33548.1|AF435011_1 NUANCE [Homo (6885) 873 169.1 9.4e-38
gi|119601250|gb|EAW80844.1| spectrin repeat contai (6825) 871 168.7 1.2e-37
gi|145699091|ref|NP_001005510.2| synaptic nuclear (6874) 826 160.6 3.2e-35
gi|210122242|gb|EEA69950.1| hypothetical protein B (8372) 806 157.1 4.5e-34
gi|109479539|ref|XP_001080795.1| PREDICTED: simila (6910) 788 153.8 3.6e-33
gi|109478368|ref|XP_216738.4| PREDICTED: similar t (3867) 783 152.7 4.4e-33
gi|115701088|ref|XP_001196159.1| PREDICTED: simila ( 966) 749 146.1 1.1e-31
gi|194034243|ref|XP_001925379.1| PREDICTED: spectr (6165) 735 144.3 2.4e-30
gi|57208507|emb|CAI42284.1| spectrin repeat contai (3321) 602 120.2 2.3e-23
gi|119568117|gb|EAW47732.1| spectrin repeat contai (3344) 602 120.2 2.3e-23
>>gi|119568121|gb|EAW47736.1| spectrin repeat containing (5509 aa)
initn: 8679 init1: 8679 opt: 8679 Z-score: 8401.0 bits: 1568.9 E(): 0
Smith-Waterman score: 8679; 99.927% identity (100.000% similar) in 1362 aa overlap (1-1362:4148-5509)
10 20 30
KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV
::::::::::::::::::::::::::::::
gi|119 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV
4120 4130 4140 4150 4160 4170
40 50 60 70 80 90
KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
4180 4190 4200 4210 4220 4230
100 110 120 130 140 150
KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
4240 4250 4260 4270 4280 4290
160 170 180 190 200 210
KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
4300 4310 4320 4330 4340 4350
220 230 240 250 260 270
KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
4360 4370 4380 4390 4400 4410
280 290 300 310 320 330
KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
4420 4430 4440 4450 4460 4470
340 350 360 370 380 390
KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
4480 4490 4500 4510 4520 4530
400 410 420 430 440 450
KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
4540 4550 4560 4570 4580 4590
460 470 480 490 500 510
KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
4600 4610 4620 4630 4640 4650
520 530 540 550 560 570
KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
4660 4670 4680 4690 4700 4710
580 590 600 610 620 630
KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
4720 4730 4740 4750 4760 4770
640 650 660 670 680 690
KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
4780 4790 4800 4810 4820 4830
700 710 720 730 740 750
KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
4840 4850 4860 4870 4880 4890
760 770 780 790 800 810
KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
gi|119 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA
4900 4910 4920 4930 4940 4950
820 830 840 850 860 870
KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
4960 4970 4980 4990 5000 5010
880 890 900 910 920 930
KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
5020 5030 5040 5050 5060 5070
940 950 960 970 980 990
KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
5080 5090 5100 5110 5120 5130
1000 1010 1020 1030 1040 1050
KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
5140 5150 5160 5170 5180 5190
1060 1070 1080 1090 1100 1110
KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
5200 5210 5220 5230 5240 5250
1120 1130 1140 1150 1160 1170
KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
5260 5270 5280 5290 5300 5310
1180 1190 1200 1210 1220 1230
KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
5320 5330 5340 5350 5360 5370
1240 1250 1260 1270 1280 1290
KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
5380 5390 5400 5410 5420 5430
1300 1310 1320 1330 1340 1350
KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
5440 5450 5460 5470 5480 5490
1360
KIAA12 HQVTLGKIIFKK
::::::::::::
gi|119 HQVTLGKIIFKK
5500
>>gi|24417709|gb|AAN60442.1| nesprin-1 [Homo sapiens] (8797 aa)
initn: 8848 init1: 8628 opt: 8628 Z-score: 8348.9 bits: 1559.9 E(): 0
Smith-Waterman score: 8628; 99.852% identity (99.926% similar) in 1355 aa overlap (1-1355:4219-5573)
10 20 30
KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV
::::::::::::::::::::::::::::::
gi|244 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV
4190 4200 4210 4220 4230 4240
40 50 60 70 80 90
KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
4250 4260 4270 4280 4290 4300
100 110 120 130 140 150
KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
4310 4320 4330 4340 4350 4360
160 170 180 190 200 210
KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
4370 4380 4390 4400 4410 4420
220 230 240 250 260 270
KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
4430 4440 4450 4460 4470 4480
280 290 300 310 320 330
KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
4490 4500 4510 4520 4530 4540
340 350 360 370 380 390
KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
4550 4560 4570 4580 4590 4600
400 410 420 430 440 450
KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
4610 4620 4630 4640 4650 4660
460 470 480 490 500 510
KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
4670 4680 4690 4700 4710 4720
520 530 540 550 560 570
KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
4730 4740 4750 4760 4770 4780
580 590 600 610 620 630
KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
4790 4800 4810 4820 4830 4840
640 650 660 670 680 690
KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
4850 4860 4870 4880 4890 4900
700 710 720 730 740 750
KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
4910 4920 4930 4940 4950 4960
760 770 780 790 800 810
KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA
4970 4980 4990 5000 5010 5020
820 830 840 850 860 870
KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
5030 5040 5050 5060 5070 5080
880 890 900 910 920 930
KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
5090 5100 5110 5120 5130 5140
940 950 960 970 980 990
KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
5150 5160 5170 5180 5190 5200
1000 1010 1020 1030 1040 1050
KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
5210 5220 5230 5240 5250 5260
1060 1070 1080 1090 1100 1110
KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
5270 5280 5290 5300 5310 5320
1120 1130 1140 1150 1160 1170
KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
5330 5340 5350 5360 5370 5380
1180 1190 1200 1210 1220 1230
KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
5390 5400 5410 5420 5430 5440
1240 1250 1260 1270 1280 1290
KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
5450 5460 5470 5480 5490 5500
1300 1310 1320 1330 1340 1350
KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|244 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
5510 5520 5530 5540 5550 5560
1360
KIAA12 HQVTLGKIIFKK
::. :
gi|244 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ
5570 5580 5590 5600 5610 5620
>>gi|119568116|gb|EAW47731.1| spectrin repeat containing (8749 aa)
initn: 8762 init1: 8624 opt: 8624 Z-score: 8345.0 bits: 1559.2 E(): 0
Smith-Waterman score: 8624; 99.779% identity (99.926% similar) in 1355 aa overlap (1-1355:4148-5502)
10 20 30
KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV
::::::::::::::::::::::::::::::
gi|119 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV
4120 4130 4140 4150 4160 4170
40 50 60 70 80 90
KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
4180 4190 4200 4210 4220 4230
100 110 120 130 140 150
KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
4240 4250 4260 4270 4280 4290
160 170 180 190 200 210
KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
4300 4310 4320 4330 4340 4350
220 230 240 250 260 270
KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
4360 4370 4380 4390 4400 4410
280 290 300 310 320 330
KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
4420 4430 4440 4450 4460 4470
340 350 360 370 380 390
KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
4480 4490 4500 4510 4520 4530
400 410 420 430 440 450
KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
4540 4550 4560 4570 4580 4590
460 470 480 490 500 510
KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
4600 4610 4620 4630 4640 4650
520 530 540 550 560 570
KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
4660 4670 4680 4690 4700 4710
580 590 600 610 620 630
KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
4720 4730 4740 4750 4760 4770
640 650 660 670 680 690
KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
4780 4790 4800 4810 4820 4830
700 710 720 730 740 750
KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
4840 4850 4860 4870 4880 4890
760 770 780 790 800 810
KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
gi|119 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA
4900 4910 4920 4930 4940 4950
820 830 840 850 860 870
KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
4960 4970 4980 4990 5000 5010
880 890 900 910 920 930
KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
5020 5030 5040 5050 5060 5070
940 950 960 970 980 990
KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
5080 5090 5100 5110 5120 5130
1000 1010 1020 1030 1040 1050
KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
5140 5150 5160 5170 5180 5190
1060 1070 1080 1090 1100 1110
KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
5200 5210 5220 5230 5240 5250
1120 1130 1140 1150 1160 1170
KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
5260 5270 5280 5290 5300 5310
1180 1190 1200 1210 1220 1230
KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
5320 5330 5340 5350 5360 5370
1240 1250 1260 1270 1280 1290
KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
5380 5390 5400 5410 5420 5430
1300 1310 1320 1330 1340 1350
KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
5440 5450 5460 5470 5480 5490
1360
KIAA12 HQVTLGKIIFKK
::. :
gi|119 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ
5500 5510 5520 5530 5540 5550
>>gi|119568112|gb|EAW47727.1| spectrin repeat containing (8757 aa)
initn: 8844 init1: 8624 opt: 8624 Z-score: 8345.0 bits: 1559.2 E(): 0
Smith-Waterman score: 8624; 99.779% identity (99.926% similar) in 1355 aa overlap (1-1355:4179-5533)
10 20 30
KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV
::::::::::::::::::::::::::::::
gi|119 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV
4150 4160 4170 4180 4190 4200
40 50 60 70 80 90
KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
4210 4220 4230 4240 4250 4260
100 110 120 130 140 150
KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
4270 4280 4290 4300 4310 4320
160 170 180 190 200 210
KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
4330 4340 4350 4360 4370 4380
220 230 240 250 260 270
KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
4390 4400 4410 4420 4430 4440
280 290 300 310 320 330
KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
4450 4460 4470 4480 4490 4500
340 350 360 370 380 390
KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
4510 4520 4530 4540 4550 4560
400 410 420 430 440 450
KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
4570 4580 4590 4600 4610 4620
460 470 480 490 500 510
KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
4630 4640 4650 4660 4670 4680
520 530 540 550 560 570
KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
4690 4700 4710 4720 4730 4740
580 590 600 610 620 630
KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
4750 4760 4770 4780 4790 4800
640 650 660 670 680 690
KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
4810 4820 4830 4840 4850 4860
700 710 720 730 740 750
KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
4870 4880 4890 4900 4910 4920
760 770 780 790 800 810
KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
gi|119 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA
4930 4940 4950 4960 4970 4980
820 830 840 850 860 870
KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
4990 5000 5010 5020 5030 5040
880 890 900 910 920 930
KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
5050 5060 5070 5080 5090 5100
940 950 960 970 980 990
KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
5110 5120 5130 5140 5150 5160
1000 1010 1020 1030 1040 1050
KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
5170 5180 5190 5200 5210 5220
1060 1070 1080 1090 1100 1110
KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
5230 5240 5250 5260 5270 5280
1120 1130 1140 1150 1160 1170
KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
5290 5300 5310 5320 5330 5340
1180 1190 1200 1210 1220 1230
KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
5350 5360 5370 5380 5390 5400
1240 1250 1260 1270 1280 1290
KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
5410 5420 5430 5440 5450 5460
1300 1310 1320 1330 1340 1350
KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
5470 5480 5490 5500 5510 5520
1360
KIAA12 HQVTLGKIIFKK
::. :
gi|119 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ
5530 5540 5550 5560 5570 5580
>>gi|119568122|gb|EAW47737.1| spectrin repeat containing (8779 aa)
initn: 8844 init1: 8624 opt: 8624 Z-score: 8345.0 bits: 1559.2 E(): 0
Smith-Waterman score: 8624; 99.779% identity (99.926% similar) in 1355 aa overlap (1-1355:4164-5518)
10 20 30
KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV
::::::::::::::::::::::::::::::
gi|119 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV
4140 4150 4160 4170 4180 4190
40 50 60 70 80 90
KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
4200 4210 4220 4230 4240 4250
100 110 120 130 140 150
KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
4260 4270 4280 4290 4300 4310
160 170 180 190 200 210
KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
4320 4330 4340 4350 4360 4370
220 230 240 250 260 270
KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
4380 4390 4400 4410 4420 4430
280 290 300 310 320 330
KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
4440 4450 4460 4470 4480 4490
340 350 360 370 380 390
KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
4500 4510 4520 4530 4540 4550
400 410 420 430 440 450
KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
4560 4570 4580 4590 4600 4610
460 470 480 490 500 510
KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
4620 4630 4640 4650 4660 4670
520 530 540 550 560 570
KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
4680 4690 4700 4710 4720 4730
580 590 600 610 620 630
KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
4740 4750 4760 4770 4780 4790
640 650 660 670 680 690
KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
4800 4810 4820 4830 4840 4850
700 710 720 730 740 750
KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
4860 4870 4880 4890 4900 4910
760 770 780 790 800 810
KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
gi|119 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA
4920 4930 4940 4950 4960 4970
820 830 840 850 860 870
KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
4980 4990 5000 5010 5020 5030
880 890 900 910 920 930
KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
5040 5050 5060 5070 5080 5090
940 950 960 970 980 990
KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
5100 5110 5120 5130 5140 5150
1000 1010 1020 1030 1040 1050
KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
5160 5170 5180 5190 5200 5210
1060 1070 1080 1090 1100 1110
KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
5220 5230 5240 5250 5260 5270
1120 1130 1140 1150 1160 1170
KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
5280 5290 5300 5310 5320 5330
1180 1190 1200 1210 1220 1230
KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
5340 5350 5360 5370 5380 5390
1240 1250 1260 1270 1280 1290
KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
5400 5410 5420 5430 5440 5450
1300 1310 1320 1330 1340 1350
KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
5460 5470 5480 5490 5500 5510
1360
KIAA12 HQVTLGKIIFKK
::. :
gi|119 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ
5520 5530 5540 5550 5560 5570
>>gi|119568124|gb|EAW47739.1| spectrin repeat containing (8797 aa)
initn: 8844 init1: 8624 opt: 8624 Z-score: 8345.0 bits: 1559.2 E(): 0
Smith-Waterman score: 8624; 99.779% identity (99.926% similar) in 1355 aa overlap (1-1355:4219-5573)
10 20 30
KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV
::::::::::::::::::::::::::::::
gi|119 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV
4190 4200 4210 4220 4230 4240
40 50 60 70 80 90
KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
4250 4260 4270 4280 4290 4300
100 110 120 130 140 150
KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
4310 4320 4330 4340 4350 4360
160 170 180 190 200 210
KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
4370 4380 4390 4400 4410 4420
220 230 240 250 260 270
KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
4430 4440 4450 4460 4470 4480
280 290 300 310 320 330
KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
4490 4500 4510 4520 4530 4540
340 350 360 370 380 390
KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
4550 4560 4570 4580 4590 4600
400 410 420 430 440 450
KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
4610 4620 4630 4640 4650 4660
460 470 480 490 500 510
KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
4670 4680 4690 4700 4710 4720
520 530 540 550 560 570
KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
4730 4740 4750 4760 4770 4780
580 590 600 610 620 630
KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
4790 4800 4810 4820 4830 4840
640 650 660 670 680 690
KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
4850 4860 4870 4880 4890 4900
700 710 720 730 740 750
KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
4910 4920 4930 4940 4950 4960
760 770 780 790 800 810
KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
gi|119 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA
4970 4980 4990 5000 5010 5020
820 830 840 850 860 870
KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
5030 5040 5050 5060 5070 5080
880 890 900 910 920 930
KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
5090 5100 5110 5120 5130 5140
940 950 960 970 980 990
KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
5150 5160 5170 5180 5190 5200
1000 1010 1020 1030 1040 1050
KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
5210 5220 5230 5240 5250 5260
1060 1070 1080 1090 1100 1110
KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
5270 5280 5290 5300 5310 5320
1120 1130 1140 1150 1160 1170
KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
5330 5340 5350 5360 5370 5380
1180 1190 1200 1210 1220 1230
KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
5390 5400 5410 5420 5430 5440
1240 1250 1260 1270 1280 1290
KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
5450 5460 5470 5480 5490 5500
1300 1310 1320 1330 1340 1350
KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
5510 5520 5530 5540 5550 5560
1360
KIAA12 HQVTLGKIIFKK
::. :
gi|119 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ
5570 5580 5590 5600 5610 5620
>>gi|22597198|gb|AAN03486.1| enaptin [Homo sapiens] (8749 aa)
initn: 8759 init1: 8621 opt: 8621 Z-score: 8342.1 bits: 1558.7 E(): 0
Smith-Waterman score: 8621; 99.705% identity (99.926% similar) in 1355 aa overlap (1-1355:4148-5502)
10 20 30
KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV
::::::::::::::::::::::::::::::
gi|225 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV
4120 4130 4140 4150 4160 4170
40 50 60 70 80 90
KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
4180 4190 4200 4210 4220 4230
100 110 120 130 140 150
KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
4240 4250 4260 4270 4280 4290
160 170 180 190 200 210
KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
4300 4310 4320 4330 4340 4350
220 230 240 250 260 270
KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
4360 4370 4380 4390 4400 4410
280 290 300 310 320 330
KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
4420 4430 4440 4450 4460 4470
340 350 360 370 380 390
KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
gi|225 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNI
4480 4490 4500 4510 4520 4530
400 410 420 430 440 450
KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
4540 4550 4560 4570 4580 4590
460 470 480 490 500 510
KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
4600 4610 4620 4630 4640 4650
520 530 540 550 560 570
KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
4660 4670 4680 4690 4700 4710
580 590 600 610 620 630
KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
4720 4730 4740 4750 4760 4770
640 650 660 670 680 690
KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
4780 4790 4800 4810 4820 4830
700 710 720 730 740 750
KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
4840 4850 4860 4870 4880 4890
760 770 780 790 800 810
KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
gi|225 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA
4900 4910 4920 4930 4940 4950
820 830 840 850 860 870
KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
4960 4970 4980 4990 5000 5010
880 890 900 910 920 930
KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
5020 5030 5040 5050 5060 5070
940 950 960 970 980 990
KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
5080 5090 5100 5110 5120 5130
1000 1010 1020 1030 1040 1050
KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
5140 5150 5160 5170 5180 5190
1060 1070 1080 1090 1100 1110
KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
5200 5210 5220 5230 5240 5250
1120 1130 1140 1150 1160 1170
KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
5260 5270 5280 5290 5300 5310
1180 1190 1200 1210 1220 1230
KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
5320 5330 5340 5350 5360 5370
1240 1250 1260 1270 1280 1290
KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
5380 5390 5400 5410 5420 5430
1300 1310 1320 1330 1340 1350
KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|225 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
5440 5450 5460 5470 5480 5490
1360
KIAA12 HQVTLGKIIFKK
::. :
gi|225 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ
5500 5510 5520 5530 5540 5550
>>gi|220675498|emb|CAX11912.1| spectrin repeat containin (8749 aa)
initn: 8759 init1: 8621 opt: 8621 Z-score: 8342.1 bits: 1558.7 E(): 0
Smith-Waterman score: 8621; 99.705% identity (99.926% similar) in 1355 aa overlap (1-1355:4148-5502)
10 20 30
KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV
::::::::::::::::::::::::::::::
gi|220 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV
4120 4130 4140 4150 4160 4170
40 50 60 70 80 90
KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
4180 4190 4200 4210 4220 4230
100 110 120 130 140 150
KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
4240 4250 4260 4270 4280 4290
160 170 180 190 200 210
KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
4300 4310 4320 4330 4340 4350
220 230 240 250 260 270
KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
4360 4370 4380 4390 4400 4410
280 290 300 310 320 330
KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
4420 4430 4440 4450 4460 4470
340 350 360 370 380 390
KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
gi|220 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNI
4480 4490 4500 4510 4520 4530
400 410 420 430 440 450
KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
4540 4550 4560 4570 4580 4590
460 470 480 490 500 510
KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
4600 4610 4620 4630 4640 4650
520 530 540 550 560 570
KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
4660 4670 4680 4690 4700 4710
580 590 600 610 620 630
KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
4720 4730 4740 4750 4760 4770
640 650 660 670 680 690
KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
4780 4790 4800 4810 4820 4830
700 710 720 730 740 750
KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
4840 4850 4860 4870 4880 4890
760 770 780 790 800 810
KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
gi|220 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA
4900 4910 4920 4930 4940 4950
820 830 840 850 860 870
KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
4960 4970 4980 4990 5000 5010
880 890 900 910 920 930
KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
5020 5030 5040 5050 5060 5070
940 950 960 970 980 990
KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
5080 5090 5100 5110 5120 5130
1000 1010 1020 1030 1040 1050
KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
5140 5150 5160 5170 5180 5190
1060 1070 1080 1090 1100 1110
KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
5200 5210 5220 5230 5240 5250
1120 1130 1140 1150 1160 1170
KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
5260 5270 5280 5290 5300 5310
1180 1190 1200 1210 1220 1230
KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
5320 5330 5340 5350 5360 5370
1240 1250 1260 1270 1280 1290
KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
5380 5390 5400 5410 5420 5430
1300 1310 1320 1330 1340 1350
KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|220 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
5440 5450 5460 5470 5480 5490
1360
KIAA12 HQVTLGKIIFKK
::. :
gi|220 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ
5500 5510 5520 5530 5540 5550
>>gi|29839561|sp|Q8NF91.2|SYNE1_HUMAN RecName: Full=Nesp (8797 aa)
initn: 8841 init1: 8621 opt: 8621 Z-score: 8342.1 bits: 1558.7 E(): 0
Smith-Waterman score: 8621; 99.705% identity (99.926% similar) in 1355 aa overlap (1-1355:4219-5573)
10 20 30
KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV
::::::::::::::::::::::::::::::
gi|298 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV
4190 4200 4210 4220 4230 4240
40 50 60 70 80 90
KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
4250 4260 4270 4280 4290 4300
100 110 120 130 140 150
KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
4310 4320 4330 4340 4350 4360
160 170 180 190 200 210
KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
4370 4380 4390 4400 4410 4420
220 230 240 250 260 270
KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
4430 4440 4450 4460 4470 4480
280 290 300 310 320 330
KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
4490 4500 4510 4520 4530 4540
340 350 360 370 380 390
KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
gi|298 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNI
4550 4560 4570 4580 4590 4600
400 410 420 430 440 450
KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
4610 4620 4630 4640 4650 4660
460 470 480 490 500 510
KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
4670 4680 4690 4700 4710 4720
520 530 540 550 560 570
KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
4730 4740 4750 4760 4770 4780
580 590 600 610 620 630
KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
4790 4800 4810 4820 4830 4840
640 650 660 670 680 690
KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
4850 4860 4870 4880 4890 4900
700 710 720 730 740 750
KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
4910 4920 4930 4940 4950 4960
760 770 780 790 800 810
KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
gi|298 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA
4970 4980 4990 5000 5010 5020
820 830 840 850 860 870
KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
5030 5040 5050 5060 5070 5080
880 890 900 910 920 930
KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
5090 5100 5110 5120 5130 5140
940 950 960 970 980 990
KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
5150 5160 5170 5180 5190 5200
1000 1010 1020 1030 1040 1050
KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
5210 5220 5230 5240 5250 5260
1060 1070 1080 1090 1100 1110
KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
5270 5280 5290 5300 5310 5320
1120 1130 1140 1150 1160 1170
KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
5330 5340 5350 5360 5370 5380
1180 1190 1200 1210 1220 1230
KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
5390 5400 5410 5420 5430 5440
1240 1250 1260 1270 1280 1290
KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
5450 5460 5470 5480 5490 5500
1300 1310 1320 1330 1340 1350
KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|298 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
5510 5520 5530 5540 5550 5560
1360
KIAA12 HQVTLGKIIFKK
::. :
gi|298 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ
5570 5580 5590 5600 5610 5620
>>gi|154277116|ref|NP_892006.2| spectrin repeat containi (8797 aa)
initn: 8841 init1: 8621 opt: 8621 Z-score: 8342.1 bits: 1558.7 E(): 0
Smith-Waterman score: 8621; 99.705% identity (99.926% similar) in 1355 aa overlap (1-1355:4219-5573)
10 20 30
KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV
::::::::::::::::::::::::::::::
gi|154 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV
4190 4200 4210 4220 4230 4240
40 50 60 70 80 90
KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL
4250 4260 4270 4280 4290 4300
100 110 120 130 140 150
KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA
4310 4320 4330 4340 4350 4360
160 170 180 190 200 210
KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS
4370 4380 4390 4400 4410 4420
220 230 240 250 260 270
KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD
4430 4440 4450 4460 4470 4480
280 290 300 310 320 330
KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ
4490 4500 4510 4520 4530 4540
340 350 360 370 380 390
KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
gi|154 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNI
4550 4560 4570 4580 4590 4600
400 410 420 430 440 450
KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE
4610 4620 4630 4640 4650 4660
460 470 480 490 500 510
KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE
4670 4680 4690 4700 4710 4720
520 530 540 550 560 570
KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ
4730 4740 4750 4760 4770 4780
580 590 600 610 620 630
KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP
4790 4800 4810 4820 4830 4840
640 650 660 670 680 690
KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS
4850 4860 4870 4880 4890 4900
700 710 720 730 740 750
KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA
4910 4920 4930 4940 4950 4960
760 770 780 790 800 810
KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
gi|154 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA
4970 4980 4990 5000 5010 5020
820 830 840 850 860 870
KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD
5030 5040 5050 5060 5070 5080
880 890 900 910 920 930
KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL
5090 5100 5110 5120 5130 5140
940 950 960 970 980 990
KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED
5150 5160 5170 5180 5190 5200
1000 1010 1020 1030 1040 1050
KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL
5210 5220 5230 5240 5250 5260
1060 1070 1080 1090 1100 1110
KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV
5270 5280 5290 5300 5310 5320
1120 1130 1140 1150 1160 1170
KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL
5330 5340 5350 5360 5370 5380
1180 1190 1200 1210 1220 1230
KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL
5390 5400 5410 5420 5430 5440
1240 1250 1260 1270 1280 1290
KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH
5450 5460 5470 5480 5490 5500
1300 1310 1320 1330 1340 1350
KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL
5510 5520 5530 5540 5550 5560
1360
KIAA12 HQVTLGKIIFKK
::. :
gi|154 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ
5570 5580 5590 5600 5610 5620
1362 residues in 1 query sequences
2693465022 residues in 7827732 library sequences
Tcomplib [34.26] (8 proc)
start: Wed Mar 4 06:35:36 2009 done: Wed Mar 4 06:39:53 2009
Total Scan time: 1936.920 Total Display time: 3.540
Function used was FASTA [version 34.26.5 April 26, 2007]