# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/fh10357.fasta.huge -Q ../query/KIAA1240.ptfa ./tmplib.24314 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 KIAA1240, 733 aa
 vs ./tmplib.24314 library

1986772 residues in  2037 sequences
  Expectation_n fit: rho(ln(x))= 5.7160+/-0.00628; mu= 12.9777+/- 0.427
 mean_var=133.4605+/-31.319, 0's: 0 Z-trim: 6  B-trim: 52 in 1/39
 Lambda= 0.111019

FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 38, opt: 26, open/ext: -10/-2, width:  16
The best scores are:                                      opt bits E(2037)
KIAA1286  ( 1214 res)   hh11961(revised)           (1214)  180 40.8 0.00092
KIAA0043  ( 731 res)   ha01331                     ( 731)  168 38.7  0.0025


>>KIAA1286  ( 1214 res)   hh11961(revised)                (1214 aa)
 initn: 174 init1: 147 opt: 180  Z-score: 159.4  bits: 40.8 E(): 0.00092
Smith-Waterman score: 180;  33.871% identity (61.290% similar) in 124 aa overlap (222-338:581-699)

             200       210       220       230        240       250
KIAA12 LNQASMAPPRRKHAALCAMEVLPLALPSPPRQLSESEKSRMEDQE-ENTLRELRLFLRDV
                                     :.  . :. ....   :  :  . ..:: .
KIAA12 TSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFNVLLRTT
              560       570       580       590       600       610

              260            270       280       290       300     
KIAA12 TKRLATDKRFNIFSKPVS-----DYLEVIKEPMDLSTVITKIDKHNYLTAKDFLKDIDLI
          :      .::..::.     :::: :..:::.::.  :...: : : ..: .:..::
KIAA12 LDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLI
              620       630       640       650       660       670

         310       320        330       340       350       360    
KIAA12 CSNALEYNPDKDPGDKIIRHRACT-LKDTAHAIIAAELDPEFNKLCEEIKEARIKRGLSV
        .: ..::  ::     : ::: . :.: . ::.                          
KIAA12 VTNCMKYNA-KDT----IFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPESPKL
               680           690       700       710       720     

          370       380       390       400       410       420    
KIAA12 TSEQINPHSTGARKTETRVEEAFRHKQRNPMDVWHNSANKCAFRVRRKSRRRSQWGKGII
                                                                   
KIAA12 EDFYRFSWEDVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSSGARTRRVRLLRREIN
         730       740       750       760       770       780     

>>KIAA0043  ( 731 res)   ha01331                          (731 aa)
 initn: 150 init1: 150 opt: 168  Z-score: 151.6  bits: 38.7 E(): 0.0025
Smith-Waterman score: 199;  23.398% identity (51.532% similar) in 359 aa overlap (220-543:293-642)

     190       200       210       220       230       240         
KIAA12 LILNQASMAPPRRKHAALCAMEVLPLALPSPPRQLSESEKSRMEDQEENTLRELRLFLRD
                                     ::..  :. .  ..  ... : :   .  .
KIAA00 ASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRYCDS
            270       280       290       300       310       320  

     250       260                 270       280       290         
KIAA12 VTKRLATDKRFNI---FSKPVS-------DYLEVIKEPMDLSTVITKIDKHNYLTAKDFL
       . ... . :.      : :::.       :: ..::.:::::::  :.: ..:  :. : 
KIAA00 ILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFA
            330       340       350       360       370       380  

     300       310       320       330       340        350        
KIAA12 KDIDLICSNALEYNPDKDPGDKIIRHRACTLKDTAHAIIAAELD-PEFNKLCEEIKEARI
        :. :. ::  .:::   :  ...   :  :.:. .  .:   : :             .
KIAA00 ADVRLMFSNCYKYNP---PDHEVVAM-ARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMV
            390          400        410       420       430        

      360         370       380               390            400   
KIAA12 KRGL--SVTSEQINPHSTGARKTETR------VEEAFR--HKQ-----RNPMDVWHNSAN
       ..:   : .::. .  : .. . : :      ..: ..  :.:     . :..  ... .
KIAA00 SKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKE
      440       450       460       470       480       490        

           410       420           430       440        450        
KIAA12 KCAFRVRRKSRRRSQWGKGII----KKRKVNNLKKDEEDTKF-ADYENHTED--RKLLEN
       :   . ..:.... .  . .     :: ::    :. .. :  :   : :    :.: ..
KIAA00 KKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKG
      500       510       520       530       540       550        

        460       470       480       490         500       510    
KIAA12 GEFEVSTDCHEENGEETGDLSMTNDESSCDIMDLDQ--GQRLNNGAGTKENFASTEEESS
       :.   ..   ::  :: : : :. ::.    .:...  :..:.  .   ..   . ..:.
KIAA00 GKQASASYDSEE--EEEG-LPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSN
      560       570          580       590       600       610     

          520       530       540       550       560       570    
KIAA12 NESLLVNSSSSLNPEQTSRKETFLKGNCLNGEASTDSFEGIPVLECQNGKLEVVSFCDSG
        . . ..  . :.:    . : ..: .::                               
KIAA00 PDEIEIDFET-LKPTTLRELERYVK-SCLQKKQRKPFSASGKKQAAKSKEELAQEKKKEL
         620        630        640       650       660       670   




733 residues in 1 query   sequences
1986772 residues in 2037 library sequences
 Scomplib [34.26]
 start: Thu Dec 18 15:14:23 2008 done: Thu Dec 18 15:14:24 2008
 Total Scan time:  0.570 Total Display time:  0.030

Function used was FASTA [version 34.26.5 April 26, 2007]