hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080501/iprscan-20080501-18583044/chunk_1/iprscan-20080501-18583044.nocrc
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Query sequence: KIAA1157
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF00481.12.fs Protein phosphatase 2C                          76.3    2.6e-21   2
PF00481.12.ls Protein phosphatase 2C                          44.7    2.9e-10   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF00481.12.ls   1/1      24   400 ..     1   303 []    44.7  2.9e-10
PF00481.12.fs   1/2     154   217 ..    82   160 ..    41.6  1.6e-11
PF00481.12.fs   2/2     302   370 ..   197   273 ..    34.8  1.3e-09

Alignments of top-scoring domains:
PF00481.12.ls: domain 1 of 1, from 24 to 400: score 44.7, E = 2.9e-10
                   *->ldvgvsrm.qgwrksmeDahialknlnssssgkdsisffavfDghgG
                      + +  +r+++++r s+  ++++  + ns+ s  +s ++   fDgh+G
    KIAA1157    24    VTSTPNRNsSKRRSSLPNGEGLQLKENSE-SEGVSCHYWSLFDGHAG 69   

                   sqaakyagkhlekaltilaerksfpegnpnEwkl................
                   s aa +a+  l     ++ e+ ++  +      + +++   +++  ++++
    KIAA1157    70 SGAAVVASRLLQ---HHITEQLQDIVD------Ilknsavlpptclgeep 110  

                   ..........................................sdledalr
                   ++++ ++++ ++  + +++ + ++++++++++  ++++ +++ ++  al 
    KIAA1157   111 entpansrtltraaslrggvgapgspstpptrfftekkipheCLVIGALE 160  

                   ksfleadtdeelrsaadsanhvltkedlssGsTAvvalirgqkklLyvAN
                   ++f e d  +e  +  +s n       +s+G+TA++++    k  LyvAN
    KIAA1157   161 SAFKEMDLQIERER--SSYN-------ISGGCTALIVICLLGK--LYVAN 199  

                   vGDSravLcrngnaiklvtqLtedHkpsdedEkrRIeaaGGfvsrvsgng
                   +GDSra+++rng++i    +++   +p  e E+ R++ +  +  +     
    KIAA1157   200 AGDSRAIIIRNGEII----PMSSEFTP--ETERQRLQYLAFMQPH----- 238  

                   RvnGv.............................................
                    + G++ ++ + +++ ++++ +++   ++ + ++   ++ ++++ + +  
    KIAA1157   239 -LLGNefthlefprrvqrkelgkkmlyrdfnmtgwayktiededlkfpli 287  

                   ...........fLavSRAfGDfelKpnvtlgpelslerGifseeqpVsae
                    +++++ +      v+R +GD++lK  ++ +  +          +  s++
    KIAA1157   288 ygegkkarvmaTIGVTRGLGDHDLKVHDSNIYIK----------PFLSSA 327  

                   Pdvtsstkite....skDeFliLAcDGlWDvvsdqeavdivrselsdgn.
                   P+v    ++++ +++s D+ liLA+DGlWDv+s++e+ + + ++l   ++
    KIAA1157   328 PEVR-IYDLSKydhgS-DDVLILATDGLWDVLSNEEVAEAITQFLPNCDp 375  

                   ksagspmeaaekLvdeAiargseDni<-*
                   +    +++aa++Lv  A+    +D +   
    KIAA1157   376 DDPHRYTLAAQDLVMRARGVL-KDRG    400  

PF00481.12.fs: domain 1 of 2, from 154 to 217: score 41.6, E = 1.6e-11
                   *->dledalrksfleadtdeelrsaadsanhvltkedlssGsTAvvalir
                      ++  al ++f e d  +e  +  +s n       +s+G+TA++++  
    KIAA1157   154    LVIGALESAFKEMDLQIERER--SSYN-------ISGGCTALIVICL 191  

                   gqkklLyvANvGDSravLcrngnaiklvtqLt<-*
                     k  LyvAN+GDSra+++rng++i    +++   
    KIAA1157   192 LGK--LYVANAGDSRAIIIRNGEII----PMS    217  

PF00481.12.fs: domain 2 of 2, from 302 to 370: score 34.8, E = 1.3e-09
                   *->vSRAfGDfelKpnvtlgpelslerGifseeqpVsaePdvtsstkite
                      v+R +GD++lK  ++ +  +          +  s++P+v    ++++
    KIAA1157   302    VTRGLGDHDLKVHDSNIYIK----------PFLSSAPEVR-IYDLSK 337  

                   ....skDeFliLAcDGlWDvvsdqeavdivrsel<-*
                    +++s D+ liLA+DGlWDv+s++e+ + + ++l   
    KIAA1157   338 ydhgS-DDVLILATDGLWDVLSNEEVAEAITQFL    370  

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