# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/hj05565.fasta.nr -Q ../query/KIAA1144.ptfa /cdna2/lib/nr/nr 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 KIAA1144, 489 aa vs /cdna2/lib/nr/nr library 2693465022 residues in 7827732 sequences statistics sampled from 60000 to 7822627 sequences Expectation_n fit: rho(ln(x))= 4.6833+/-0.000179; mu= 13.7570+/- 0.010 mean_var=67.0114+/-13.203, 0's: 36 Z-trim: 64 B-trim: 0 in 0/66 Lambda= 0.156675 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 37, opt: 25, open/ext: -10/-2, width: 16 The best scores are: opt bits E(7827732) gi|24418481|sp|Q9ULS6.2|KCNS2_HUMAN RecName: Full= ( 477) 3168 725.1 9.6e-207 gi|109087045|ref|XP_001094800.1| PREDICTED: potass ( 477) 3161 723.5 2.9e-206 gi|194036997|ref|XP_001928892.1| PREDICTED: simila ( 477) 3149 720.8 1.9e-205 gi|119906727|ref|XP_592772.3| PREDICTED: similar t ( 477) 3141 719.0 6.6e-205 gi|73974094|ref|XP_539100.2| PREDICTED: similar to ( 510) 3139 718.6 9.5e-205 gi|24418461|sp|Q9ER26.1|KCNS2_RAT RecName: Full=Po ( 477) 3123 714.9 1.1e-203 gi|24418468|sp|O35174.1|KCNS2_MOUSE RecName: Full= ( 477) 3123 714.9 1.1e-203 gi|126322140|ref|XP_001369106.1| PREDICTED: simila ( 477) 2992 685.3 9.1e-195 gi|118087222|ref|XP_428021.2| PREDICTED: similar t ( 447) 2493 572.5 7.8e-161 gi|149622655|ref|XP_001514820.1| PREDICTED: simila ( 504) 2493 572.6 8.5e-161 gi|47217887|emb|CAG05009.1| unnamed protein produc ( 479) 2483 570.3 3.9e-160 gi|118100541|ref|XP_001232667.1| PREDICTED: simila ( 469) 1786 412.7 1e-112 gi|189520680|ref|XP_001922193.1| PREDICTED: simila ( 487) 1778 410.9 3.7e-112 gi|81897133|sp|Q8BQZ8.1|KCNS3_MOUSE RecName: Full= ( 491) 1710 395.6 1.6e-107 gi|148666013|gb|EDK98429.1| mCG1037961 [Mus muscul ( 491) 1710 395.6 1.6e-107 gi|109102073|ref|XP_001092885.1| PREDICTED: potass ( 491) 1707 394.9 2.5e-107 gi|24418459|sp|O88759.1|KCNS3_RAT RecName: Full=Po ( 491) 1706 394.7 3e-107 gi|149408753|ref|XP_001506624.1| PREDICTED: simila ( 494) 1705 394.4 3.5e-107 gi|50745143|ref|XP_426211.1| PREDICTED: similar to ( 494) 1704 394.2 4.1e-107 gi|62630224|gb|AAX88969.1| unknown [Homo sapiens] ( 491) 1703 394.0 4.7e-107 gi|160142685|sp|Q9BQ31.2|KCNS3_HUMAN RecName: Full ( 491) 1702 393.7 5.5e-107 gi|16198531|gb|AAH15947.1| Potassium voltage-gated ( 491) 1702 393.7 5.5e-107 gi|54697186|gb|AAV38965.1| potassium voltage-gated ( 492) 1702 393.7 5.6e-107 gi|2739121|gb|AAB94882.1| Shab-related delayed-rec ( 491) 1701 393.5 6.5e-107 gi|24418478|sp|Q9TT17.1|KCNS3_RABIT RecName: Full= ( 491) 1700 393.3 7.6e-107 gi|13278747|gb|AAH04148.1| Potassium voltage-gated ( 491) 1698 392.8 1e-106 gi|30584613|gb|AAP36559.1| Homo sapiens potassium ( 492) 1698 392.8 1e-106 gi|60652544|gb|AAX33295.1| potassium voltage-gated ( 491) 1697 392.6 1.2e-106 gi|67097562|gb|AAY67751.1| potassium voltage-gated ( 491) 1696 392.4 1.4e-106 gi|126305418|ref|XP_001362177.1| PREDICTED: simila ( 492) 1687 390.4 5.8e-106 gi|57098457|ref|XP_540095.1| PREDICTED: similar to ( 491) 1686 390.1 6.8e-106 gi|194220944|ref|XP_001918281.1| PREDICTED: simila ( 491) 1681 389.0 1.5e-105 gi|189543121|ref|XP_699543.3| PREDICTED: similar t ( 379) 1568 363.4 6e-98 gi|190337460|gb|AAI63398.1| Similar to potassium v ( 499) 1537 356.5 9.5e-96 gi|47210943|emb|CAF91112.1| unnamed protein produc ( 487) 1493 346.5 9.2e-93 gi|47212422|emb|CAF93578.1| unnamed protein produc ( 697) 1355 315.4 2.9e-83 gi|81097675|gb|AAI09402.1| Zgc:123261 [Danio rerio ( 424) 1268 295.6 1.7e-77 gi|55962430|emb|CAI11829.1| novel protein similar ( 416) 1264 294.7 3.1e-77 gi|56207944|emb|CAI21201.1| novel protein similar ( 494) 1077 252.5 1.9e-64 gi|109129350|ref|XP_001112505.1| PREDICTED: potass ( 519) 1009 237.1 8.2e-60 gi|80479036|gb|AAI09204.1| Potassium voltage-gated ( 519) 1004 236.0 1.8e-59 gi|109111683|ref|XP_001086960.1| PREDICTED: simila ( 545) 1004 236.0 1.9e-59 gi|26006803|sp|Q8TDN1.1|KCNG4_HUMAN RecName: Full= ( 519) 1002 235.5 2.5e-59 gi|119615894|gb|EAW95488.1| potassium voltage-gate ( 539) 1002 235.6 2.5e-59 gi|114663882|ref|XP_523443.2| PREDICTED: potassium ( 519) 997 234.4 5.4e-59 gi|114623626|ref|XP_528530.2| PREDICTED: potassium ( 545) 995 234.0 7.7e-59 gi|26006804|sp|Q8TDN2.1|KCNV2_HUMAN RecName: Full= ( 545) 989 232.6 2e-58 gi|149042788|gb|EDL96362.1| potassium voltage-gate ( 514) 984 231.5 4.1e-58 gi|125827081|ref|XP_695650.2| PREDICTED: hypotheti ( 518) 981 230.8 6.6e-58 gi|187595284|sp|A2BDX4.1|KCNG1_MOUSE RecName: Full ( 514) 979 230.3 9e-58 >>gi|24418481|sp|Q9ULS6.2|KCNS2_HUMAN RecName: Full=Pota (477 aa) initn: 3168 init1: 3168 opt: 3168 Z-score: 3867.9 bits: 725.1 E(): 9.6e-207 Smith-Waterman score: 3168; 100.000% identity (100.000% similar) in 477 aa overlap (13-489:1-477) 10 20 30 40 50 60 KIAA11 RPRAARAAGASSMTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL :::::::::::::::::::::::::::::::::::::::::::::::: gi|244 MTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL 10 20 30 40 70 80 90 100 110 120 KIAA11 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW 50 60 70 80 90 100 130 140 150 160 170 180 KIAA11 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN 110 120 130 140 150 160 190 200 210 220 230 240 KIAA11 FRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 FRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFE 170 180 190 200 210 220 250 260 270 280 290 300 KIAA11 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLA 230 240 250 260 270 280 310 320 330 340 350 360 KIAA11 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY 290 300 310 320 330 340 370 380 390 400 410 420 KIAA11 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL 350 360 370 380 390 400 430 440 450 460 470 480 KIAA11 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS 410 420 430 440 450 460 KIAA11 ELSLNDSLR ::::::::: gi|244 ELSLNDSLR 470 >>gi|109087045|ref|XP_001094800.1| PREDICTED: potassium (477 aa) initn: 3161 init1: 3161 opt: 3161 Z-score: 3859.4 bits: 723.5 E(): 2.9e-206 Smith-Waterman score: 3161; 100.000% identity (100.000% similar) in 476 aa overlap (13-488:1-476) 10 20 30 40 50 60 KIAA11 RPRAARAAGASSMTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL :::::::::::::::::::::::::::::::::::::::::::::::: gi|109 MTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL 10 20 30 40 70 80 90 100 110 120 KIAA11 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW 50 60 70 80 90 100 130 140 150 160 170 180 KIAA11 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN 110 120 130 140 150 160 190 200 210 220 230 240 KIAA11 FRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 FRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFE 170 180 190 200 210 220 250 260 270 280 290 300 KIAA11 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLA 230 240 250 260 270 280 310 320 330 340 350 360 KIAA11 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY 290 300 310 320 330 340 370 380 390 400 410 420 KIAA11 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL 350 360 370 380 390 400 430 440 450 460 470 480 KIAA11 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS 410 420 430 440 450 460 KIAA11 ELSLNDSLR :::::::: gi|109 ELSLNDSLH 470 >>gi|194036997|ref|XP_001928892.1| PREDICTED: similar to (477 aa) initn: 3149 init1: 3149 opt: 3149 Z-score: 3844.7 bits: 720.8 E(): 1.9e-205 Smith-Waterman score: 3149; 99.370% identity (100.000% similar) in 476 aa overlap (13-488:1-476) 10 20 30 40 50 60 KIAA11 RPRAARAAGASSMTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL :::::::::::::::::::::::::::::::::::::::::::::::: gi|194 MTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL 10 20 30 40 70 80 90 100 110 120 KIAA11 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW 50 60 70 80 90 100 130 140 150 160 170 180 KIAA11 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN 110 120 130 140 150 160 190 200 210 220 230 240 KIAA11 FRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFE ::::::::::::::::::::::.::::::.:::::::::::::::::::::.:::::::: gi|194 FRRQLWLALDNPGYSVLSRVFSVLSILVVLGSIITMCLNSLPDFQIPDSQGTPGEDPRFE 170 180 190 200 210 220 250 260 270 280 290 300 KIAA11 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLA 230 240 250 260 270 280 310 320 330 340 350 360 KIAA11 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY 290 300 310 320 330 340 370 380 390 400 410 420 KIAA11 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL 350 360 370 380 390 400 430 440 450 460 470 480 KIAA11 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS 410 420 430 440 450 460 KIAA11 ELSLNDSLR :::::::: gi|194 ELSLNDSLH 470 >>gi|119906727|ref|XP_592772.3| PREDICTED: similar to Po (477 aa) initn: 3141 init1: 3141 opt: 3141 Z-score: 3834.9 bits: 719.0 E(): 6.6e-205 Smith-Waterman score: 3141; 98.950% identity (99.790% similar) in 476 aa overlap (13-488:1-476) 10 20 30 40 50 60 KIAA11 RPRAARAAGASSMTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL :::::::::::::::::::::::::::.:::::::::::::::::::: gi|119 MTGQSLWDVSEANVEDGEIRINVGGFKKRLRSHTLLRFPETRLGRLLL 10 20 30 40 70 80 90 100 110 120 KIAA11 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: gi|119 CHSREAILELCDDYDDAQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW 50 60 70 80 90 100 130 140 150 160 170 180 KIAA11 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN 110 120 130 140 150 160 190 200 210 220 230 240 KIAA11 FRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFE ::::::::::::::::::::::.::::::.:::::::::::::::::: ::::::::::: gi|119 FRRQLWLALDNPGYSVLSRVFSVLSILVVLGSIITMCLNSLPDFQIPDRQGNPGEDPRFE 170 180 190 200 210 220 250 260 270 280 290 300 KIAA11 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLA 230 240 250 260 270 280 310 320 330 340 350 360 KIAA11 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY 290 300 310 320 330 340 370 380 390 400 410 420 KIAA11 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL 350 360 370 380 390 400 430 440 450 460 470 480 KIAA11 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS 410 420 430 440 450 460 KIAA11 ELSLNDSLR :::::::: gi|119 ELSLNDSLH 470 >>gi|73974094|ref|XP_539100.2| PREDICTED: similar to Pot (510 aa) initn: 3139 init1: 3139 opt: 3139 Z-score: 3832.1 bits: 718.6 E(): 9.5e-205 Smith-Waterman score: 3139; 96.509% identity (99.179% similar) in 487 aa overlap (1-487:22-508) 10 20 30 KIAA11 RPRAARAAGASSMTGQSLWDVSEANVEDGEIRINVGGFK : ::::: :::::: .: ::..::::::::::.:::::. gi|739 MPTSRSGKFPAGLGRGPPCSQRRRAARAPGASSMTRRSPWDANEANVEDGEIRVNVGGFR 10 20 30 40 50 60 40 50 60 70 80 90 KIAA11 RRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHT ::::::::::::::::::::::.::::::::::::::.:::::::::::::::::::::: gi|739 RRLRSHTLLRFPETRLGRLLLCRSREAILELCDDYDDAQREFYFDRNPELFPYVLHFYHT 70 80 90 100 110 120 100 110 120 130 140 150 KIAA11 GKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 GKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSS 130 140 150 160 170 180 160 170 180 190 200 210 KIAA11 FDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLN ::::::::.:::::::::::::::::::::::::::::::.::.::::::.::::::::: gi|739 FDEILAFYSDASKFDGQPLGNFRRQLWLALDNPGYSVLSRIFSVLSILVVLGSIITMCLN 190 200 210 220 230 240 220 230 240 250 260 270 KIAA11 SLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 SLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMS 250 260 270 280 290 300 280 290 300 310 320 330 KIAA11 IVPFYITLVVNLVVESTPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 IVPFYITLVVNLVVESTPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYK 310 320 330 340 350 360 340 350 360 370 380 390 KIAA11 EVGLLLLYLSVGISIFSVVAYTIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAG :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: gi|739 EVGLLLLYLSVGISIFSVVAYTIEKEENEGLTTIPACWWWATVSMTTVGYGDVVPGTTAG 370 380 390 400 410 420 400 410 420 430 440 450 KIAA11 KLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDY ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: gi|739 KLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSINLRDY 430 440 450 460 470 480 460 470 480 KIAA11 YAHKVKSLMASLTNMSRSSPSELSLNDSLR :::::::::::::::::::::::::::: gi|739 YAHKVKSLMASLTNMSRSSPSELSLNDSPH 490 500 510 >>gi|24418461|sp|Q9ER26.1|KCNS2_RAT RecName: Full=Potass (477 aa) initn: 3123 init1: 3123 opt: 3123 Z-score: 3812.9 bits: 714.9 E(): 1.1e-203 Smith-Waterman score: 3123; 98.319% identity (99.790% similar) in 476 aa overlap (13-488:1-476) 10 20 30 40 50 60 KIAA11 RPRAARAAGASSMTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL :: :::::.::..::::::::::::::::::::::::::::::::::: gi|244 MTRQSLWDLSETDVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL 10 20 30 40 70 80 90 100 110 120 KIAA11 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW 50 60 70 80 90 100 130 140 150 160 170 180 KIAA11 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN 110 120 130 140 150 160 190 200 210 220 230 240 KIAA11 FRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFE ::::::::::::::::::::::.::::::.:::::::::::::::::::::::::::::: gi|244 FRRQLWLALDNPGYSVLSRVFSVLSILVVLGSIITMCLNSLPDFQIPDSQGNPGEDPRFE 170 180 190 200 210 220 250 260 270 280 290 300 KIAA11 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: gi|244 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESSPTLA 230 240 250 260 270 280 310 320 330 340 350 360 KIAA11 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY 290 300 310 320 330 340 370 380 390 400 410 420 KIAA11 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL 350 360 370 380 390 400 430 440 450 460 470 480 KIAA11 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS 410 420 430 440 450 460 KIAA11 ELSLNDSLR ::::.::: gi|244 ELSLDDSLH 470 >>gi|24418468|sp|O35174.1|KCNS2_MOUSE RecName: Full=Pota (477 aa) initn: 3123 init1: 3123 opt: 3123 Z-score: 3812.9 bits: 714.9 E(): 1.1e-203 Smith-Waterman score: 3123; 98.319% identity (99.790% similar) in 476 aa overlap (13-488:1-476) 10 20 30 40 50 60 KIAA11 RPRAARAAGASSMTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL :: :::::::...::::::::::::::::::::::::::::::::::: gi|244 MTRQSLWDVSDTDVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL 10 20 30 40 70 80 90 100 110 120 KIAA11 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW 50 60 70 80 90 100 130 140 150 160 170 180 KIAA11 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN 110 120 130 140 150 160 190 200 210 220 230 240 KIAA11 FRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFE ::::::::::::::::::::::.::::::.:::::::::::::::::::::::::::::: gi|244 FRRQLWLALDNPGYSVLSRVFSVLSILVVLGSIITMCLNSLPDFQIPDSQGNPGEDPRFE 170 180 190 200 210 220 250 260 270 280 290 300 KIAA11 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: gi|244 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESSPTLA 230 240 250 260 270 280 310 320 330 340 350 360 KIAA11 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY 290 300 310 320 330 340 370 380 390 400 410 420 KIAA11 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL 350 360 370 380 390 400 430 440 450 460 470 480 KIAA11 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS 410 420 430 440 450 460 KIAA11 ELSLNDSLR ::::.::: gi|244 ELSLDDSLH 470 >>gi|126322140|ref|XP_001369106.1| PREDICTED: similar to (477 aa) initn: 2992 init1: 2992 opt: 2992 Z-score: 3652.9 bits: 685.3 E(): 9.1e-195 Smith-Waterman score: 2992; 93.697% identity (98.529% similar) in 476 aa overlap (13-488:1-476) 10 20 30 40 50 60 KIAA11 RPRAARAAGASSMTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLL :::::: :.:::: ::.:: .::::::..:::::::::::::::::: gi|126 MTGQSLSDLSEANFEDSEISVNVGGFKKKLRSHTLLRFPETRLGRLLH 10 20 30 40 70 80 90 100 110 120 KIAA11 CHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYW :.:.:.::::::::::.: ::::::::::::::::::.:::::::.:::::::::::::: gi|126 CRSKESILELCDDYDDAQNEFYFDRNPELFPYVLHFYNTGKLHVMGELCVFSFSQEIEYW 50 60 70 80 90 100 130 140 150 160 170 180 KIAA11 GINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN :::::::::::::::::::.::.::::::::::::::::::::::::::::::::::::: gi|126 GINEFFIDSCCSYSYHGRKMEPDQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGN 110 120 130 140 150 160 190 200 210 220 230 240 KIAA11 FRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFE .::::::::::::::.::::::::::.::.:::.:::::::::: :::::::: :::::: gi|126 LRRQLWLALDNPGYSILSRVFSILSIMVVLGSIVTMCLNSLPDFLIPDSQGNPEEDPRFE 170 180 190 200 210 220 250 260 270 280 290 300 KIAA11 IVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLA ::::::::::::::::::::.:.:.:::::::::::::::.::::::::::::::.:::: gi|126 IVEHFGIAWFTFELVARFAVTPEFFKFFKNALNLIDLMSIIPFYITLVVNLVVESSPTLA 230 240 250 260 270 280 310 320 330 340 350 360 KIAA11 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|126 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY 290 300 310 320 330 340 370 380 390 400 410 420 KIAA11 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|126 TIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITL 350 360 370 380 390 400 430 440 450 460 470 480 KIAA11 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|126 IFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPS 410 420 430 440 450 460 KIAA11 ELSLNDSLR :::::::: gi|126 ELSLNDSLH 470 >>gi|118087222|ref|XP_428021.2| PREDICTED: similar to po (447 aa) initn: 2492 init1: 2492 opt: 2493 Z-score: 3043.7 bits: 572.5 E(): 7.8e-161 Smith-Waterman score: 2493; 88.732% identity (95.775% similar) in 426 aa overlap (64-488:21-446) 40 50 60 70 80 90 KIAA11 NVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDR-NPELFPY :: :. . . ..: .. ::::::: gi|118 MEGRGAGSRRGEVGEEKRKEREMEREMGEKESREKKEREREKGNPELFPY 10 20 30 40 50 100 110 120 130 140 150 KIAA11 VLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQSD :::::.:::::: .:: ::::::::::::::::::::::::::::::.::.::::.:::: gi|118 VLHFYNTGKLHVRGELRVFSFSQEIEYWGINEFFIDSCCSYSYHGRKMEPDQEKWEEQSD 60 70 80 90 100 110 160 170 180 190 200 210 KIAA11 QESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILSILVVMGS :::::::::::::::::::::: ::.::.::::::::::::::::::.::.:::.::.:: gi|118 QESTTSSFDEILAFYNDASKFDKQPFGNIRRQLWLALDNPGYSVLSRIFSVLSIVVVLGS 120 130 140 150 160 170 220 230 240 250 260 270 KIAA11 IITMCLNSLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKNAL :.::::::: :::: ::.:.: ::::::::::::::::::::::::::::::::::..:: gi|118 IVTMCLNSLSDFQIIDSSGTPEEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFQHAL 180 190 200 210 220 230 280 290 300 310 320 330 KIAA11 NLIDLMSIVPFYITLVVNLVVESTPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGA ::::::::.::::::.:::::::.:::::::::::::::::::::::::::::::::::: gi|118 NLIDLMSILPFYITLIVNLVVESSPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGA 240 250 260 270 280 290 340 350 360 370 380 390 KIAA11 TLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKEENEGLATIPACWWWATVSMTTVGYGDV ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|118 TLKYSYREVGLLLLYLSVGISIFSVVAYTIEKEENEGLATIPACWWWATVSMTTVGYGDV 300 310 320 330 340 350 400 410 420 430 440 450 KIAA11 VPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVP :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|118 VPGSTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVP 360 370 380 390 400 410 460 470 480 KIAA11 SVNLRDYYAHKVKSLMASLTNMSRSSPSELSLNDSLR :::::::::.:::::::::::::::.:::::::::: gi|118 SVNLRDYYAYKVKSLMASLTNMSRSTPSELSLNDSLH 420 430 440 >>gi|149622655|ref|XP_001514820.1| PREDICTED: similar to (504 aa) initn: 2000 init1: 2000 opt: 2493 Z-score: 3043.0 bits: 572.6 E(): 8.5e-161 Smith-Waterman score: 2493; 79.406% identity (92.994% similar) in 471 aa overlap (20-488:35-503) 10 20 30 40 KIAA11 RPRAARAAGASSMTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLR :::... .::: :::::.:..: .:.:: gi|149 TGGGPVLQLCTTLSAVHNGFVVHALLSTRQDVSQTEQAEGEICINVGGLKQKLLPRTVLR 10 20 30 40 50 60 50 60 70 80 90 100 KIAA11 FPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELC :::::::::: : :: ::::::::::: : :.::::.:.:::::::::.:::::: ..:: gi|149 FPETRLGRLLRCGSRAAILELCDDYDDSQGEYYFDRDPRLFPYVLHFYRTGKLHVTGQLC 70 80 90 100 110 120 110 120 130 140 150 160 KIAA11 VFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQ--EKWDEQSDQESTTSSFDEILAFY :::::::::::::.:. ::.::. .:.:::.:: ..:...:..::..:::::.:::: gi|149 VFSFSQEIEYWGIDELSIDACCGPGYRGRKTEPTAGPDRWEDRSERESAASSFDELLAFY 130 140 150 160 170 180 170 180 190 200 210 220 KIAA11 NDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIP :::.:::.::: .::.::::::::: :: ::.:..::.:::.:::.::::::::::. : gi|149 RDASRFDGRPLGRLRRRLWLALDNPGRSVPSRAFGVLSVLVVLGSIVTMCLNSLPDFR-P 190 200 210 220 230 240 230 240 250 260 270 280 KIAA11 DSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITL . : ::::::: ::.::::::::::.::::::::: .::.::::::::.::::::.:: gi|149 -AGGRAGEDPRFEAVERFGIAWFTFELLARFAVAPDFSRFFRNALNLIDLLSIVPFYVTL 250 260 270 280 290 300 290 300 310 320 330 340 KIAA11 VVNLVVESTPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLY .::::.::.:.::::::::::::::::::::::::::::::::::::::::.:::::::: gi|149 AVNLVAESSPALANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYREVGLLLLY 310 320 330 340 350 360 350 360 370 380 390 400 KIAA11 LSVGISIFSVVAYTIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACI ::::::::::::::.:.:..:::::::::::::::::::::::::::::.:::::::::: gi|149 LSVGISIFSVVAYTVEREDDEGLATIPACWWWATVSMTTVGYGDVVPGTAAGKLTASACI 370 380 390 400 410 420 410 420 430 440 450 460 KIAA11 LAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSL ::::::::::::::::::::::::::::::::::: :::: :::::::::::: .:::: gi|149 LAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCRFGDGTGEVPSVNLRDYYACRVKSL 430 440 450 460 470 480 470 480 KIAA11 MASLTNMSRSSPSELSLNDSLR :::::..: ::::::::.::: gi|149 MASLTDVSGSSPSELSLSDSLD 490 500 489 residues in 1 query sequences 2693465022 residues in 7827732 library sequences Tcomplib [34.26] (8 proc) start: Tue Mar 3 22:03:13 2009 done: Tue Mar 3 22:07:46 2009 Total Scan time: 1562.860 Total Display time: 0.190 Function used was FASTA [version 34.26.5 April 26, 2007]