hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-18081727/chunk_1/iprscan-20080501-18081727.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1127 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF07974.3.ls EGF-like domain 139.7 7.3e-39 6 PF07974.3.fs EGF-like domain 129.7 7.6e-36 6 PF00008.17.ls EGF-like domain 116.0 1e-31 6 PF00008.17.fs EGF-like domain 105.6 9.6e-29 6 PF01436.11.fs NHL repeat 64.7 1e-16 6 PF05593.4.ls RHS Repeat 65.6 1.5e-16 6 PF05593.4.fs RHS Repeat 59.6 3.1e-16 7 PF01436.11.ls NHL repeat 56.1 1.1e-13 6 PF01414.9.fs Delta serrate ligand 35.9 2.2e-10 6 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00008.17.ls 1/6 10 37 .. 1 38 [] 20.0 0.0082 PF07974.3.ls 1/6 10 37 .. 1 37 [] 28.6 2.1e-05 PF07974.3.fs 1/6 10 37 .. 1 37 [] 26.9 1.6e-06 PF00008.17.fs 2/6 42 69 .. 1 38 [] 23.6 1e-05 PF00008.17.ls 2/6 42 69 .. 1 38 [] 25.3 0.0002 PF07974.3.ls 2/6 42 69 .. 1 37 [] 24.4 0.00038 PF07974.3.ls 3/6 76 104 .. 1 37 [] 24.7 0.00031 PF07974.3.ls 4/6 109 135 .. 1 37 [] 22.5 0.0014 PF07974.3.ls 5/6 140 166 .. 1 37 [] 22.1 0.0019 PF00008.17.fs 5/6 140 166 .. 1 38 [] 24.2 7e-06 PF00008.17.ls 5/6 140 166 .. 1 38 [] 25.9 0.00013 PF00008.17.ls 6/6 180 210 .. 1 38 [] 22.9 0.0011 PF01436.11.fs 1/6 607 627 .. 1 22 [. 7.6 0.59 PF01436.11.ls 1/6 607 633 .. 1 29 [] 2.4 6.8 PF01436.11.ls 2/6 652 683 .. 1 29 [] 3.4 5.1 PF01436.11.fs 2/6 661 680 .. 7 26 .. 10.2 0.11 PF01436.11.ls 3/6 725 750 .. 1 29 [] 3.8 4.6 PF01436.11.ls 4/6 784 819 .. 1 29 [] 16.0 0.12 PF01436.11.fs 4/6 784 819 .. 1 29 [] 14.0 0.0095 PF01436.11.ls 5/6 844 871 .. 1 29 [] 3.8 4.6 PF01436.11.ls 6/6 913 940 .. 1 29 [] 26.6 8e-05 PF01436.11.fs 6/6 913 940 .. 1 29 [] 24.7 1.1e-05 PF05593.4.fs 1/7 1052 1090 .. 1 44 [] 21.4 2.4e-05 PF05593.4.ls 2/6 1052 1090 .. 1 44 [] 23.3 0.00081 PF05593.4.ls 3/6 1370 1406 .. 1 44 [] 11.2 1.5 PF05593.4.ls 4/6 1575 1611 .. 1 44 [] 17.4 0.049 PF05593.4.ls 5/6 1650 1688 .. 1 44 [] 10.6 1.8 Alignments of top-scoring domains: PF00008.17.ls: domain 1 of 6, from 10 to 37: score 20.0, E = 0.0082 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C + C ++G C+d+ C C G y+G++C KIAA1127 10 CIDP--SCGGHGSCIDG----NCVCSAG----YKGEHC 37 PF07974.3.ls: domain 1 of 6, from 10 to 37: score 28.6, E = 2.1e-05 *->C....CngshGtCvspngtstpcgkCvCdsgyedkyqGadC<-* C +++C+g hG C+ g+CvC+ g y G +C KIAA1127 10 CidpsCGG-HGSCI--------DGNCVCSAG----YKGEHC 37 PF07974.3.fs: domain 1 of 6, from 10 to 37: score 26.9, E = 1.6e-06 *->C....CngshGtCvspngtstpcgkCvCdsgyedkyqGadC<-* C +++C+g hG C+ g+CvC+ g y G +C KIAA1127 10 CidpsCGG-HGSCI--------DGNCVCSAG----YKGEHC 37 PF00008.17.fs: domain 2 of 6, from 42 to 69: score 23.6, E = 1e-05 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C + Cs +G Cv++ +C C pG + G +C KIAA1127 42 CLDP--TCSSHGVCVNG----ECLCSPG----WGGLNC 69 PF00008.17.ls: domain 2 of 6, from 42 to 69: score 25.3, E = 0.0002 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C + Cs +G Cv++ +C C pG + G +C KIAA1127 42 CLDP--TCSSHGVCVNG----ECLCSPG----WGGLNC 69 PF07974.3.ls: domain 2 of 6, from 42 to 69: score 24.4, E = 0.00038 *->C....CngshGtCvspngtstpcgkCvCdsgyedkyqGadC<-* C +++C+ hG+Cv g C C++g + G C KIAA1127 42 CldptCSS-HGVCV--------NGECLCSPG----WGGLNC 69 PF07974.3.ls: domain 3 of 6, from 76 to 104: score 24.7, E = 0.00031 *->C...CngshGtCvspngtstpcgkCvCdsgyedkyqGadC<-* C+++C+g hGt + p +g C+Cd+ + G+dC KIAA1127 76 CpdqCSG-HGT-YLPD-----TGLCSCDPN----WMGPDC 104 PF07974.3.ls: domain 4 of 6, from 109 to 135: score 22.5, E = 0.0014 *->C...CngshGtCvspngtstpcgkCvCdsgyedkyqGadC<-* C+ +C+ hG+C+ g C C+ g ++Ga+C KIAA1127 109 CsvdCGT-HGVCI--------GGACRCEEG----WTGAAC 135 PF07974.3.ls: domain 5 of 6, from 140 to 166: score 22.1, E = 0.0019 *->C...CngshGtCvspngtstpcgkCvCdsgyedkyqGadC<-* C+++C + hGtC gkC+C g + G +C KIAA1127 140 ChprCIE-HGTCK--------DGKCECREG----WNGEHC 166 PF00008.17.fs: domain 5 of 6, from 140 to 166: score 24.2, E = 7e-06 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C+p C +GtC d+ +CeC +G ++G++C KIAA1127 140 CHP---RCIEHGTCKDG----KCECREG----WNGEHC 166 PF00008.17.ls: domain 5 of 6, from 140 to 166: score 25.9, E = 0.00013 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C+p C +GtC d+ +CeC +G ++G++C KIAA1127 140 CHP---RCIEHGTCKDG----KCECREG----WNGEHC 166 PF00008.17.ls: domain 6 of 6, from 180 to 210: score 22.9, E = 0.0011 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C++ C+++G+C+ ++++++C C+ G + G+ C KIAA1127 180 CPD---LCNGNGRCTLGQNSWQCVCQTG----WRGPGC 210 PF01436.11.fs: domain 1 of 6, from 607 to 627: score 7.6, E = 0.59 *->lnrPhGvavdpsdGrvyVaDse<-* l P +av+ dG +yV D++ KIAA1127 607 LLAPVALAVG-IDGSLYVGDFN 627 PF01436.11.ls: domain 1 of 6, from 607 to 633: score 2.4, E = 6.8 *->lnrPhGvavdpsdGrvyVaDsenhrvqvf<-* l P +av+ dG +yV D++ r ++f KIAA1127 607 LLAPVALAVG-IDGSLYVGDFNYIR-RIF 633 PF01436.11.ls: domain 2 of 6, from 652 to 683: score 3.4, E = 5.1 *->lnrPhG...vavdpsdGrvyVaDsenhrvqvf<-* n+P+ + +avdp +G +yV+D++ r+ KIAA1127 652 SNNPAHkyyLAVDPVSGSLYVSDTNSRRIYRV 683 PF01436.11.fs: domain 2 of 6, from 661 to 680: score 10.2, E = 0.11 *->vavdpsdGrvyVaDsenhrv<-* +avdp +G +yV+D++ r+ KIAA1127 661 LAVDPVSGSLYVSDTNSRRI 680 PF01436.11.ls: domain 3 of 6, from 725 to 750: score 3.8, E = 4.6 *->lnrPhGvavdpsdGrvyVaDsenhrvqvf<-* l +P+G+avd ++G y +D +++ KIAA1127 725 LMSPRGIAVD-KNGLMYFVD--ATMIRKV 750 PF01436.11.ls: domain 4 of 6, from 784 to 819: score 16.0, E = 0.12 *->lnrPhGvavdpsdGrvyVaD.......senhrvqvf<-* l P+++av+p d+ +yV +++ + +enh+v ++ KIAA1127 784 LEWPTDLAVNPMDNSLYVLEnnvilriTENHQVSII 819 PF01436.11.fs: domain 4 of 6, from 784 to 819: score 14.0, E = 0.0095 *->lnrPhGvavdpsdGrvyVaD.......senhrvqvf<-* l P+++av+p d+ +yV +++ + +enh+v ++ KIAA1127 784 LEWPTDLAVNPMDNSLYVLEnnvilriTENHQVSII 819 PF01436.11.ls: domain 5 of 6, from 844 to 871: score 3.8, E = 4.6 *->lnrPhGvavdpsdGrvyVaDsenhrvqvf<-* l + + +a++ +G +y+++++ ++ + KIAA1127 844 LESASAIAIS-HTGVLYITETDEKKINRL 871 PF01436.11.ls: domain 6 of 6, from 913 to 940: score 26.6, E = 8e-05 *->lnrPhGvavdpsdGrvyVaDsenhrvqvf<-* ln+P+++av +dG++y+aD +n r++ KIAA1127 913 LNSPSSLAVA-PDGTIYIADLGNIRIRAV 940 PF01436.11.fs: domain 6 of 6, from 913 to 940: score 24.7, E = 1.1e-05 *->lnrPhGvavdpsdGrvyVaDsenhrvqvf<-* ln+P+++av +dG++y+aD +n r++ KIAA1127 913 LNSPSSLAVA-PDGTIYIADLGNIRIRAV 940 PF05593.4.fs: domain 1 of 7, from 1052 to 1090: score 21.4, E = 2.4e-05 *->YDadGrLtavt.dpsggvgttyrYDaaGrltaltlttstdagGrt<- YD + L+a+ +d +g ++ y YD++Grlt + t + G++ KIAA1127 1052 YDGNTGLLATKsDETGWTT-FYDYDHEGRLTNV-----TRPTGVV 1090 * KIAA1127 - - PF05593.4.ls: domain 2 of 6, from 1052 to 1090: score 23.3, E = 0.00081 *->YDadGrLtavt.dpsggvgttyrYDaaGrltaltlttstdagGrt<- YD + L+a+ +d +g ++ y YD++Grlt + t + G++ KIAA1127 1052 YDGNTGLLATKsDETGWTT-FYDYDHEGRLTNV-----TRPTGVV 1090 * KIAA1127 - - PF05593.4.ls: domain 3 of 6, from 1370 to 1406: score 11.2, E = 1.5 *->YDadGrLtavt.dpsggvgttyrYDaaGrltaltlttstdagGrt<- Y++dGr+++++ +g+++ y Y+++ l ++ + + t KIAA1127 1370 YSDDGRILKTSfLGTGRQV-FYKYGKLSKLSEI-----VYDS--T 1406 * KIAA1127 - - PF05593.4.ls: domain 4 of 6, from 1575 to 1611: score 17.4, E = 0.049 *->YDadGrLtavtdpsggvgttyrYDaaGrltaltlttstdagGrt<-* YD dG+L +v ++ +++ +y+YD G+l ++ ++g + KIAA1127 1575 YDGDGQLQSVAVNDRPTW-RYSYDLNGNL--HL----LNPGNSV 1611 PF05593.4.ls: domain 5 of 6, from 1650 to 1688: score 10.6, E = 1.8 *->YDadGrLtavt.dpsggvgttyrYDaaGrltaltlttstdagGrt<- Y++ G Lt ++ +sg ++ +yrYD+ Gr+ + + G KIAA1127 1650 YNSKGLLTRAYnKASGWSV-QYRYDGVGRRASY-----KTNLGHH 1688 * KIAA1127 - - //