hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-17213769/chunk_1/iprscan-20080501-17213769.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1099 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF01412.9.ls Putative GTPase activating protein for Arf 187.5 3.1e-53 1 PF01412.9.fs Putative GTPase activating protein for Arf 185.6 4.3e-53 1 PF08477.3.fs Miro-like protein 121.2 1e-34 1 PF08477.3.ls Miro-like protein 123.0 7.7e-34 1 PF00169.19.fs PH domain 58.5 2.4e-17 1 PF00169.19.ls PH domain 60.5 5.1e-15 1 PF00023.20.fs Ankyrin repeat 50.0 5.7e-13 2 PF00023.20.ls Ankyrin repeat 48.4 2.2e-11 2 PF00071.12.ls Ras family 8.7 5.9e-10 1 PF00071.12.fs Ras family 33.7 8.5e-10 2 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF08477.3.ls 1/1 133 241 .. 1 139 [] 123.0 7.7e-34 PF00071.12.ls 1/1 133 291 .. 1 174 [] 8.7 5.9e-10 PF08477.3.fs 1/1 133 241 .. 1 139 [] 121.2 1e-34 PF00071.12.fs 2/2 198 291 .. 73 174 .] 21.4 3.8e-06 PF00169.19.fs 1/1 407 595 .. 1 92 [] 58.5 2.4e-17 PF00169.19.ls 1/1 407 595 .. 1 92 [] 60.5 5.1e-15 PF01412.9.ls 1/1 616 736 .. 1 137 [] 187.5 3.1e-53 PF01412.9.fs 1/1 616 736 .. 1 137 [] 185.6 4.3e-53 PF00023.20.fs 1/2 775 807 .. 1 33 [] 38.2 1.1e-09 PF00023.20.ls 1/2 775 807 .. 1 33 [] 40.2 6.4e-09 PF00023.20.ls 2/2 808 840 .. 1 33 [] 8.2 1.9 PF00023.20.fs 2/2 808 833 .. 1 26 [. 11.8 0.026 Alignments of top-scoring domains: PF08477.3.ls: domain 1 of 1, from 133 to 241: score 123.0, E = 7.7e-34 *->kvvViGdkgvGKSSllqallgeefppniPrvLpkkklpreiqgstya kv+++G+ +GKS+l++++l+++++ ++e+ +++ + KIAA1099 133 KVGIVGNLASGKSALVHRYLTGTYV------------QEESPEGGRF 167 vdtlevdgdtklenvrlkefllilwDtggreelkfehepiAymktaDavl +++++vdg+ +l l+++D+gg +e++f + Dav+ KIAA1099 168 KKEIVVDGQSYL---------LLIRDEGGPPEAQF-------AMWVDAVI 201 lvyDlsdpeSfervsslikwlpnlrklgkkaiPvilvgnKlD<-* +v++l+d+ Sf+ v+ ++ + +n r + ++iP++lvg+++ KIAA1099 202 FVFSLEDEISFQTVYHYYSRMANYR--NTSEIPLVLVGTQDA 241 PF00071.12.ls: domain 1 of 1, from 133 to 291: score 8.7, E = 5.9e-10 *->KlVlvGDgGVGKSsLliRFtdnkFpeeYipTIGvD....Fytktvev K+ +vG+ + GKS+L++R+ ++++++e + ++++ + k ++v KIAA1099 133 KVGIVGNLASGKSALVHRYLTGTYVQE------ESpeggRFKKEIVV 173 dgktvkLqIWDTAGQErFralrpaYYRgAqGfLLVYDITsrdSFenvkkW dg+ + L I D G ++ ++++ V++ ++ SF+ v ++ KIAA1099 174 DGQSYLLLIRDEGG-----PPEAQFAMWVDAVIFVFSLEDEISFQTVYHY 218 leeilrhadkdenvpivLVGNKcDLeddedlele.kqkRqVsteeGealA ++ ++ + e +p vLVG+ D + + R+++ +++++l KIAA1099 219 YSRMANYRNTSE-IPLVLVGTQ-DAIS------SaNP-RVIDDARARKLS 259 kelgAlpFmETSAKtneNVeeaFeelareilk<-* +l+ + ++ET A + NVe +F+++a++i + KIAA1099 260 NDLKRCTYYETCATYGLNVERVFQDVAQKIVA 291 PF08477.3.fs: domain 1 of 1, from 133 to 241: score 121.2, E = 1e-34 *->kvvViGdkgvGKSSllqallgeefppniPrvLpkkklpreiqgstya kv+++G+ +GKS+l++++l+++++ ++e+ +++ + KIAA1099 133 KVGIVGNLASGKSALVHRYLTGTYV------------QEESPEGGRF 167 vdtlevdgdtklenvrlkefllilwDtggreelkfehepiAymktaDavl +++++vdg+ +l l+++D+gg +e++f + Dav+ KIAA1099 168 KKEIVVDGQSYL---------LLIRDEGGPPEAQF-------AMWVDAVI 201 lvyDlsdpeSfervsslikwlpnlrklgkkaiPvilvgnKlD<-* +v++l+d+ Sf+ v+ ++ + +n r + ++iP++lvg+++ KIAA1099 202 FVFSLEDEISFQTVYHYYSRMANYR--NTSEIPLVLVGTQDA 241 PF00071.12.fs: domain 2 of 2, from 198 to 291: score 21.4, E = 3.8e-06 *->qGfLLVYDITsrdSFenvkkWleeilrhadkdenvpivLVGNKcDLe ++++ V++ ++ SF+ v ++++ ++ + e +p vLVG+ D KIAA1099 198 DAVIFVFSLEDEISFQTVYHYYSRMANYRNTSE-IPLVLVGTQ-DAI 242 ddedlele.kqkRqVsteeGealAkelgAlpFmETSAKtneNVeeaFeel + + R+++ +++++l +l+ + ++ET A + NVe +F+++ KIAA1099 243 S------SaNP-RVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDV 285 areilk<-* a++i + KIAA1099 286 AQKIVA 291 PF00169.19.fs: domain 1 of 1, from 407 to 595: score 58.5, E = 2.4e-17 *->vikeGwLlkkg...gkkswkkRyfvLfd.dvLlyykdkk....kkpk +ik+G Llk+++++ +k+wkk y++L+d++vL+y+ + ++ + + KIAA1099 407 PIKQGMLLKRSgksLNKEWKKKYVTLCDnGVLTYHPSLHdymqNVHG 453 gsipLsgiqvtkvpdn.................................. + i+L +v+ + + +++ ++ + +++++++ +++ ++ + ++++++ KIAA1099 454 KEIDLLRTTVKVPGKRppratsacapisspktnglskdmsslhispnsdt 503 .................................................. + +++ ++++ +++++++ +++++++ +++++++++++++ + ++ +++ KIAA1099 504 glgdsvcsspsissttspkldpppsphanrkkhrrkkstsnfkadglsgt 553 ....krkncFeirt.dretlllqaeseeerkeWvkaiqsair<-* +++++++ F i++ +++t++++a+++eer Wv+ai+s+i KIAA1099 554 aeeqEENFEFIIVSlTGQTWHFEATTYEERDAWVQAIESQIL 595 PF00169.19.ls: domain 1 of 1, from 407 to 595: score 60.5, E = 5.1e-15 *->vikeGwLlkkg...gkkswkkRyfvLfd.dvLlyykdkk....kkpk +ik+G Llk+++++ +k+wkk y++L+d++vL+y+ + ++ + + KIAA1099 407 PIKQGMLLKRSgksLNKEWKKKYVTLCDnGVLTYHPSLHdymqNVHG 453 gsipLsgiqvtkvpdn.................................. + i+L +v+ + + +++ ++ + +++++++ +++ ++ + ++++++ KIAA1099 454 KEIDLLRTTVKVPGKRppratsacapisspktnglskdmsslhispnsdt 503 .................................................. + +++ ++++ +++++++ +++++++ +++++++++++++ + ++ +++ KIAA1099 504 glgdsvcsspsissttspkldpppsphanrkkhrrkkstsnfkadglsgt 553 ....krkncFeirt.dretlllqaeseeerkeWvkaiqsair<-* +++++++ F i++ +++t++++a+++eer Wv+ai+s+i KIAA1099 554 aeeqEENFEFIIVSlTGQTWHFEATTYEERDAWVQAIESQIL 595 PF01412.9.ls: domain 1 of 1, from 616 to 736: score 187.5, E = 3.1e-53 *->qrvlqlLrsldpgNkkCfDCgavpnPtWaSvnlGvflCieCSGiHRn + +lq +r+ + gN++C DC nP WaS+nlG++ CieCSGiHRn KIAA1099 616 AMALQSIRNMR-GNSHCVDCET-QNPNWASLNLGALMCIECSGIHRN 660 LfGvHiSkVnvRSltLDsWtpeelrklesckgGNenansfwEsnlddfsl L G+H+S+V RSl+LD W+ e ++++ +GNe ans+wE + + KIAA1099 661 L-GTHLSRV--RSLDLDDWPIELIKVMS--SIGNELANSVWEESSQGRTK 705 kpkdsdaaavKCqddrqkyesfiaaKYeeklfvlkeeqee<-* ++ ds r+++e +i+aKYe+klf+ ++++ e KIAA1099 706 PSVDST---------REEKERWIRAKYEQKLFLAPLPCTE 736 PF01412.9.fs: domain 1 of 1, from 616 to 736: score 185.6, E = 4.3e-53 *->qrvlqlLrsldpgNkkCfDCgavpnPtWaSvnlGvflCieCSGiHRn + +lq +r+ + gN++C DC nP WaS+nlG++ CieCSGiHRn KIAA1099 616 AMALQSIRNMR-GNSHCVDCET-QNPNWASLNLGALMCIECSGIHRN 660 LfGvHiSkVnvRSltLDsWtpeelrklesckgGNenansfwEsnlddfsl L G+H+S+V RSl+LD W+ e ++++ +GNe ans+wE + + KIAA1099 661 L-GTHLSRV--RSLDLDDWPIELIKVMS--SIGNELANSVWEESSQGRTK 705 kpkdsdaaavKCqddrqkyesfiaaKYeeklfvlkeeqee<-* ++ ds r+++e +i+aKYe+klf+ ++++ e KIAA1099 706 PSVDST---------REEKERWIRAKYEQKLFLAPLPCTE 736 PF00023.20.fs: domain 1 of 2, from 775 to 807: score 38.2, E = 1.1e-09 *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-* dG+T+LHlA+++gn+ +++lL+ +G d+ a+d KIAA1099 775 DGRTALHLACRKGNVVLAQLLIWYGVDVTARDA 807 PF00023.20.ls: domain 1 of 2, from 775 to 807: score 40.2, E = 6.4e-09 *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-* dG+T+LHlA+++gn+ +++lL+ +G d+ a+d KIAA1099 775 DGRTALHLACRKGNVVLAQLLIWYGVDVTARDA 807 PF00023.20.ls: domain 2 of 2, from 808 to 840: score 8.2, E = 1.9 *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-* +G+T+L +A + + e++ Ll++G+ KIAA1099 808 HGNTALAYARQASSQECIDVLLQYGCPDERFVL 840 PF00023.20.fs: domain 2 of 2, from 808 to 833: score 11.8, E = 0.026 *->dGfTPLHlAalrgnlevvklLlsqGA<-* +G+T+L +A + + e++ Ll++G+ KIAA1099 808 HGNTALAYARQASSQECIDVLLQYGC 833 //