# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/hh04271.fasta.nr -Q ../query/KIAA1051.ptfa /cdna2/lib/nr/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
KIAA1051, 402 aa
vs /cdna2/lib/nr/nr library
2693465022 residues in 7827732 sequences
statistics sampled from 60000 to 7809896 sequences
Expectation_n fit: rho(ln(x))= 6.4748+/-0.000202; mu= 5.3014+/- 0.011
mean_var=123.0154+/-23.192, 0's: 41 Z-trim: 76 B-trim: 0 in 0/67
Lambda= 0.115636
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 37, opt: 25, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7827732)
gi|172046699|sp|Q86TG7.2|PEG10_HUMAN RecName: Full ( 708) 2811 479.9 7.5e-133
gi|194209640|ref|XP_001915670.1| PREDICTED: patern ( 765) 2691 459.9 8.4e-127
gi|187761320|ref|NP_001120682.1| paternally expres ( 788) 2625 448.9 1.8e-123
gi|187829058|ref|NP_001120696.1| paternally expres ( 758) 2444 418.7 2.1e-114
gi|172045711|sp|Q7TN75.2|PEG10_MOUSE RecName: Full ( 958) 1011 179.8 2.3e-42
gi|98985814|ref|NP_570947.2| paternally expressed (1006) 1011 179.8 2.4e-42
gi|149064935|gb|EDM15011.1| rCG28175, isoform CRA_ ( 279) 822 147.8 2.9e-33
gi|80751092|tpe|CAI99872.1| TPA: pol-like protein ( 205) 491 92.4 9.6e-17
gi|125855955|ref|XP_001338587.1| PREDICTED: simila (1836) 485 92.2 9.9e-16
gi|189519150|ref|XP_001919628.1| PREDICTED: simila (1217) 481 91.4 1.2e-15
gi|6425168|gb|AAC33526.2| pol polyprotein [Takifug (1187) 480 91.2 1.3e-15
gi|189528210|ref|XP_001919417.1| PREDICTED: simila (1504) 477 90.8 2.2e-15
gi|125821918|ref|XP_001335440.1| PREDICTED: simila (1513) 477 90.8 2.2e-15
gi|189532468|ref|XP_001337557.2| PREDICTED: simila ( 858) 473 90.0 2.2e-15
gi|189528767|ref|XP_001336340.2| PREDICTED: simila ( 956) 473 90.0 2.4e-15
gi|189520941|ref|XP_001342237.2| PREDICTED: simila (1173) 467 89.1 5.7e-15
gi|189535466|ref|XP_001921691.1| PREDICTED: simila (1454) 467 89.1 6.7e-15
gi|189523418|ref|XP_001921910.1| PREDICTED: simila (2892) 467 89.4 1.1e-14
gi|125810888|ref|XP_001343503.1| PREDICTED: simila (1388) 462 88.3 1.1e-14
gi|189535305|ref|XP_001922239.1| PREDICTED: simila (1770) 461 88.2 1.5e-14
gi|125817891|ref|XP_001333427.1| PREDICTED: simila (1462) 457 87.5 2.1e-14
gi|189524252|ref|XP_001919893.1| PREDICTED: simila (1462) 457 87.5 2.1e-14
gi|189528216|ref|XP_001919501.1| PREDICTED: simila (1462) 457 87.5 2.1e-14
gi|189518409|ref|XP_001920391.1| PREDICTED: simila (1672) 457 87.5 2.4e-14
gi|189527527|ref|XP_001335065.2| PREDICTED: simila (1087) 453 86.7 2.7e-14
gi|189521596|ref|XP_001334744.2| PREDICTED: simila (1100) 453 86.7 2.7e-14
gi|125850860|ref|XP_001344511.1| PREDICTED: simila (1141) 452 86.6 3.2e-14
gi|189527593|ref|XP_001921322.1| PREDICTED: simila (1085) 451 86.4 3.4e-14
gi|125833727|ref|XP_001340055.1| PREDICTED: simila (1363) 442 85.0 1.1e-13
gi|189525446|ref|XP_001919487.1| PREDICTED: simila (1417) 440 84.6 1.5e-13
gi|125819866|ref|XP_001341694.1| PREDICTED: simila (1445) 440 84.6 1.5e-13
gi|189532532|ref|XP_001921242.1| PREDICTED: simila (1401) 439 84.5 1.7e-13
gi|189519531|ref|XP_001920084.1| PREDICTED: simila (1420) 436 84.0 2.4e-13
gi|189521594|ref|XP_001333878.2| PREDICTED: simila (1425) 436 84.0 2.4e-13
gi|189529750|ref|XP_001335585.2| PREDICTED: centau (1365) 435 83.8 2.6e-13
gi|189532453|ref|XP_001332116.2| PREDICTED: simila (1399) 432 83.3 3.7e-13
gi|189525127|ref|XP_001919506.1| PREDICTED: simila (1335) 421 81.4 1.3e-12
gi|189518461|ref|XP_001921604.1| PREDICTED: simila ( 991) 419 81.0 1.3e-12
gi|125842556|ref|XP_001342733.1| PREDICTED: simila (1428) 421 81.5 1.3e-12
gi|189538126|ref|XP_001921951.1| PREDICTED: simila (1433) 421 81.5 1.3e-12
gi|189521728|ref|XP_001919545.1| PREDICTED: simila (1319) 398 77.6 1.8e-11
gi|189534356|ref|XP_001344083.2| PREDICTED: simila (1064) 378 74.2 1.6e-10
gi|189527569|ref|XP_001920780.1| PREDICTED: simila (1224) 378 74.2 1.7e-10
gi|189520809|ref|XP_001920813.1| PREDICTED: simila (1406) 372 73.3 3.8e-10
gi|148686743|gb|EDL18690.1| mCG1047978 [Mus muscul (1189) 367 72.4 6e-10
gi|114654916|ref|XP_520846.2| PREDICTED: similar t ( 968) 364 71.8 7.3e-10
gi|81865170|sp|Q7M732.1|RTL1_MOUSE RecName: Full=R (1744) 367 72.5 8e-10
gi|199562283|ref|NP_001128360.1| retrotransposon-l (1358) 364 71.9 9.4e-10
gi|190360291|sp|A6NKG5.2|RTL1_HUMAN RecName: Full= (1359) 364 71.9 9.4e-10
gi|189538019|ref|XP_001338707.2| PREDICTED: simila (1187) 360 71.2 1.4e-09
>>gi|172046699|sp|Q86TG7.2|PEG10_HUMAN RecName: Full=Ret (708 aa)
initn: 2811 init1: 2811 opt: 2811 Z-score: 2541.3 bits: 479.9 E(): 7.5e-133
Smith-Waterman score: 2811; 100.000% identity (100.000% similar) in 390 aa overlap (13-402:319-708)
10 20 30 40
KIAA10 QLSCQGLKVFAGGKLPGPAVEGPSATGPEIIRSPQDDASSPH
::::::::::::::::::::::::::::::
gi|172 RRKLNLCLYCGTGGHYADNCPAKASKSSPAGKLPGPAVEGPSATGPEIIRSPQDDASSPH
290 300 310 320 330 340
50 60 70 80 90 100
KIAA10 LQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAIDGRPIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|172 LQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAIDGRPIA
350 360 370 380 390 400
110 120 130 140 150 160
KIAA10 SGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWSTRSIVFDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|172 SGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWSTRSIVFDSE
410 420 430 440 450 460
170 180 190 200 210 220
KIAA10 YCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYRVYQPVRYYYVQNVYTPVDEHVYPDHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|172 YCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYRVYQPVRYYYVQNVYTPVDEHVYPDHRL
470 480 490 500 510 520
230 240 250 260 270 280
KIAA10 VDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTIAPNGAQVLQVKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|172 VDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTIAPNGAQVLQVKRG
530 540 550 560 570 580
290 300 310 320 330 340
KIAA10 WKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQIPGYQTYPTYAAYPTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|172 WKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQIPGYQTYPTYAAYPTY
590 600 610 620 630 640
350 360 370 380 390 400
KIAA10 PVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPPPPPPPPSYSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|172 PVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPPPPPPPPSYSTL
650 660 670 680 690 700
>>gi|194209640|ref|XP_001915670.1| PREDICTED: paternally (765 aa)
initn: 2821 init1: 1537 opt: 2691 Z-score: 2432.7 bits: 459.9 E(): 8.4e-127
Smith-Waterman score: 2691; 95.641% identity (98.462% similar) in 390 aa overlap (13-402:377-765)
10 20 30 40
KIAA10 QLSCQGLKVFAGGKLPGPAVEGPSATGPEIIRSPQDDASSPH
::::::::::::::::::::::::::::::
gi|194 RRRKLNLCLYCGNGGHYADNCPAKAAKASPGKLPGPAVEGPSATGPEIIRSPQDDASSPH
350 360 370 380 390 400
50 60 70 80 90 100
KIAA10 LQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAIDGRPIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAIDGRPIA
410 420 430 440 450 460
110 120 130 140 150 160
KIAA10 SGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWSTRSIVFDSE
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
gi|194 SGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSIHDPNITWSTRSIVFDSE
470 480 490 500 510 520
170 180 190 200 210 220
KIAA10 YCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYRVYQPVRYYYVQNVYTPVDEHVYPDHRL
:::.:::::::::::::::: :: .:::::: ::: :.::::::::::::::.:::::::
gi|194 YCRFHCRMYSPIPPSLPPPA-QPSFYYPVDGCRVYPPMRYYYVQNVYTPVDENVYPDHRL
530 540 550 560 570 580
230 240 250 260 270 280
KIAA10 VDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTIAPNGAQVLQVKRG
::: ::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
gi|194 VDPTIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTVAPNGAQVLQVKRG
590 600 610 620 630 640
290 300 310 320 330 340
KIAA10 WKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQIPGYQTYPTYAAYPTY
:::::::::::::.::::::::::::::::::::::::::.:::::::::::::..::::
gi|194 WKLQVSYDCRAPNSFTIQNQYPRLSIPNLEDQAHLATYTEYVPQIPGYQTYPTYGTYPTY
650 660 670 680 690 700
350 360 370 380 390 400
KIAA10 PVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPPPPPPPPSYSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::..
gi|194 PVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPPPPPPPPSYSAI
710 720 730 740 750 760
>>gi|187761320|ref|NP_001120682.1| paternally expressed (788 aa)
initn: 2787 init1: 1081 opt: 2625 Z-score: 2373.0 bits: 448.9 E(): 1.8e-123
Smith-Waterman score: 2625; 92.695% identity (97.229% similar) in 397 aa overlap (8-402:394-788)
10 20 30
KIAA10 QLSCQGLKVFAGGKLPGPAVEGPSATGPEIIRSPQDD
:. .:::::::::::::::::.:::::::
gi|187 EEKERRRKLNLCLYCGNGGHYADNCPAKASKASPAGKLPGPAVEGPSATGPELIRSPQDD
370 380 390 400 410 420
40 50 60 70 80 90
KIAA10 A-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAI
: :::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
gi|187 AASSPHLQVMLQIHLPGRHSLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAI
430 440 450 460 470 480
100 110 120 130 140 150
KIAA10 DGRPIASGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWSTRS
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
gi|187 DGRPIASGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPIVLGVRWLSTHDPNITWSTRS
490 500 510 520 530 540
160 170 180 190 200 210
KIAA10 IVFDSEYCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYRVYQPVRYYYVQNVYTPVDEHV
:::::::::::::::::::: ::::: :: .::::.::::::::::::::::::::::.:
gi|187 IVFDSEYCRYHCRMYSPIPPPLPPPA-QPAFYYPVEGYRVYQPVRYYYVQNVYTPVDENV
550 560 570 580 590 600
220 230 240 250 260 270
KIAA10 YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTIAPNGAQV
:::::::::.:::::::::::::::::::: :::::::::::.:::::::::::::::::
gi|187 YPDHRLVDPNIEMIPGAHSIPSGHVYSLSESEMAALRDFVARHVKDGLITPTIAPNGAQV
610 620 630 640 650 660
280 290 300 310 320 330
KIAA10 LQVKRGWKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQIPGYQTYPTY
::::::::::::::::.::. :::::::::.::::.::::::::::.::::::: :::.:
gi|187 LQVKRGWKLQVSYDCRGPNGVTIQNQYPRLTIPNLDDQAHLATYTEYVPQIPGYPTYPAY
670 680 690 700 710 720
340 350 360 370 380 390
KIAA10 AAYPTYPVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPPPPPPP
: :::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
gi|187 A-YPTYPVGFAWYPVGRDGHGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPPPPPPP
730 740 750 760 770 780
400
KIAA10 P-SYSTL
: :::.:
gi|187 PPSYSAL
>>gi|187829058|ref|NP_001120696.1| paternally expressed (758 aa)
initn: 1308 init1: 1308 opt: 2444 Z-score: 2210.1 bits: 418.7 E(): 2.1e-114
Smith-Waterman score: 2444; 93.750% identity (97.826% similar) in 368 aa overlap (8-374:392-758)
10 20 30
KIAA10 QLSCQGLKVFAGGKLPGPAVEGPSATGPEIIRSPQDD
:. .:::::::::::::::::.:::::::
gi|187 EEKERRRKLNLCLYCGNGGHYADNCPAKASKASPAGKLPGPAVEGPSATGPELIRSPQDD
370 380 390 400 410 420
40 50 60 70 80 90
KIAA10 A-SSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAI
: :::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
gi|187 AASSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRVKDWPILVEAI
430 440 450 460 470 480
100 110 120 130 140 150
KIAA10 DGRPIASGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWSTRS
:::::::::::::::::::::::::::::::: ::::::.::::::::::::::::::::
gi|187 DGRPIASGPVVHETHDLIVDLGDHREVLSFDVIQSPFFPIVLGVRWLSTHDPNITWSTRS
490 500 510 520 530 540
160 170 180 190 200 210
KIAA10 IVFDSEYCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYRVYQPVRYYYVQNVYTPVDEHV
:::::::::::::::::::: ::::: :: .::::.::::::::::::::::::::::.:
gi|187 IVFDSEYCRYHCRMYSPIPPPLPPPA-QPSFYYPVEGYRVYQPVRYYYVQNVYTPVDENV
550 560 570 580 590 600
220 230 240 250 260 270
KIAA10 YPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTIAPNGAQV
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
gi|187 YPDHRLVDPNIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTIAPNGAQV
610 620 630 640 650 660
280 290 300 310 320 330
KIAA10 LQVKRGWKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQIPGYQTYPTY
:::::::::::::::::::::.:::::::::::::.::::::::::.::::::: :::.:
gi|187 LQVKRGWKLQVSYDCRAPNNFXIQNQYPRLSIPNLDDQAHLATYTEYVPQIPGYPTYPAY
670 680 690 700 710 720
340 350 360 370 380 390
KIAA10 AAYPTYPVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPPPPPPP
:.:::::::::::::::::.::::::::::::::::::
gi|187 ATYPTYPVGFAWYPVGRDGHGRSLYVPVMITWNPHWYR
730 740 750
400
KIAA10 PSYSTL
>>gi|172045711|sp|Q7TN75.2|PEG10_MOUSE RecName: Full=Ret (958 aa)
initn: 1880 init1: 977 opt: 1011 Z-score: 916.7 bits: 179.8 E(): 2.3e-42
Smith-Waterman score: 1735; 50.345% identity (60.000% similar) in 580 aa overlap (13-397:370-947)
10 20 30 40
KIAA10 QLSCQGLKVFAGGKLPGPAVEGPSATGPEIIRSPQDDASSPH
:::::::: :::::::: :::: ..::. :
gi|172 RRKMNLCLYCGNGGHFADTCPAKASKNSPPGKLPGPAVGGPSATGPERIRSPPSEASTQH
340 350 360 370 380 390
50 60 70 80 90 100
KIAA10 LQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAIDGRPIA
::::::::.::: ::::::::::::::::::...: ::.:::::::::..::::::.:::
gi|172 LQVMLQIHMPGRPTLFVRAMIDSGASGNFIDQDFVIQNAIPLRIKDWPVMVEAIDGHPIA
400 410 420 430 440 450
110 120 130 140 150 160
KIAA10 SGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWSTRSIVFDSE
:::.. ::: ::::::::::.::::::::::::.:::.::::::::.::::::::::.:.
gi|172 SGPIILETHHLIVDLGDHREILSFDVTQSPFFPIVLGIRWLSTHDPHITWSTRSIVFNSD
460 470 480 490 500 510
170
KIAA10 YCRYHCRMYSPIP---------PSL-----------------------------------
::: .:::.. :: :.:
gi|172 YCRLRCRMFAQIPSNLLFTVPQPNLHPYLLHHVHPHVHPHMHQHLHQHLHQFLHPDPHQY
520 530 540 550 560 570
180
KIAA10 ---------------------------------------PP-------------------
::
gi|172 PHPDPHYHHHQQADMQHQLQQYLYQYLYYHLYPVMHHHLPPDQHEHLHEYLHQYLHQYLH
580 590 600 610 620 630
KIAA10 ------------------------------------------------------------
gi|172 QFLHHHLHPDLHQYLYQYLHNHMNPDPHHHPHPDPPQDPHHPPHQDPHQHPDPHQDPPHQ
640 650 660 670 680 690
190 200
KIAA10 ---------------------PAPQP------------PLYYPVDGYRVYQPVRYYYVQN
: ::: :..: . :.:.:.::::::.::
gi|172 DPHQDAHQDPHMDPHLHQHQHPQPQPHPQQHPNHPQQPPFFYHMAGFRIYHPVRYYYIQN
700 710 720 730 740 750
210 220 230 240 250 260
KIAA10 VYTPVDEHVYPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITP
::::::::::: ::.:::.:::::::::.::::.::.:: :: :::.:: :::::::.::
gi|172 VYTPVDEHVYPGHRVVDPNIEMIPGAHSLPSGHLYSMSESEMNALRNFVDRNVKDGLMTP
760 770 780 790 800 810
270 280 290 300 310 320
KIAA10 TIAPNGAQVLQVKRGWKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQI
:.::::::::::::::::::.:.::::.. :::::: :.:.::. : ::::.: ::: :.
gi|172 TVAPNGAQVLQVKRGWKLQVTYNCRAPQSGTIQNQYLRMSLPNMGDPAHLASYGEFV-QV
820 830 840 850 860 870
330 340 350 360 370 380
KIAA10 PGYQTYPTYAAYPTYPVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPP
::: ::.:. : . . :::::::: .:: . :::.:::. . ::::::::::::::
gi|172 PGYP-YPAYVYYTSPHMMTAWYPVGRDVHGRIIVVPVVITWSQNTNRQPPVPQYPPPQPP
880 890 900 910 920 930
390 400
KIAA10 PPPPPPPPPPSYSTL
::::::::::
gi|172 PPPPPPPPPPPPPPASSCSAA
940 950
>>gi|98985814|ref|NP_570947.2| paternally expressed 10 i (1006 aa)
initn: 1880 init1: 977 opt: 1011 Z-score: 916.4 bits: 179.8 E(): 2.4e-42
Smith-Waterman score: 1639; 46.497% identity (55.414% similar) in 628 aa overlap (13-397:370-995)
10 20 30 40
KIAA10 QLSCQGLKVFAGGKLPGPAVEGPSATGPEIIRSPQDDASSPH
:::::::: :::::::: :::: ..::. :
gi|989 RRKMNLCLYCGNGGHFADTCPAKASKNSPPGKLPGPAVGGPSATGPERIRSPPSEASTQH
340 350 360 370 380 390
50 60 70 80 90 100
KIAA10 LQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAIDGRPIA
::::::::.::: ::::::::::::::::::...: ::.:::::::::..::::::.:::
gi|989 LQVMLQIHMPGRPTLFVRAMIDSGASGNFIDQDFVIQNAIPLRIKDWPVMVEAIDGHPIA
400 410 420 430 440 450
110 120 130 140 150 160
KIAA10 SGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWSTRSIVFDSE
:::.. ::: ::::::::::.::::::::::::.:::.::::::::.::::::::::.:.
gi|989 SGPIILETHHLIVDLGDHREILSFDVTQSPFFPIVLGIRWLSTHDPHITWSTRSIVFNSD
460 470 480 490 500 510
170
KIAA10 YCRYHCRMYSPIP---------PSL-----------------------------------
::: .:::.. :: :.:
gi|989 YCRLRCRMFAQIPSNLLFTVPQPNLHPYLLHHVHPHVHPHMHQHLHQHLHQFLHPDPHQY
520 530 540 550 560 570
180
KIAA10 ---------------------------------------PP-------------------
::
gi|989 PHPDPHYHHHQQADMQHQLQQYLYQYLYYHLYPVMHHHLPPDQHEHLHEYLHQYLHQYLH
580 590 600 610 620 630
KIAA10 ------------------------------------------------------------
gi|989 QFLHHHLHPDLHQYLYQYLHNHMNPDPHHHPHPDPPQDPHHPPHQDPHQHPDPHQDPPHQ
640 650 660 670 680 690
KIAA10 ------------------------------------------------------------
gi|989 DPHQHPDPHQDPPHQDPHQHPDPHQDPPHQDPHQDAHQHQDPHQDAHQDPHQDAHQDPHM
700 710 720 730 740 750
190 200 210
KIAA10 ---------PAPQP------------PLYYPVDGYRVYQPVRYYYVQNVYTPVDEHVYPD
: ::: :..: . :.:.:.::::::.:::::::::::::
gi|989 DPHLHQHQHPQPQPHPQQHPNHPQQPPFFYHMAGFRIYHPVRYYYIQNVYTPVDEHVYPG
760 770 780 790 800 810
220 230 240 250 260 270
KIAA10 HRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTIAPNGAQVLQV
::.:::.:::::::::.::::.::.:: :: :::.:: :::::::.:::.::::::::::
gi|989 HRVVDPNIEMIPGAHSLPSGHLYSMSESEMNALRNFVDRNVKDGLMTPTVAPNGAQVLQV
820 830 840 850 860 870
280 290 300 310 320 330
KIAA10 KRGWKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQIPGYQTYPTYAAY
::::::::.:.::::.. :::::: :.:.::. : ::::.: ::: :.::: ::.:. :
gi|989 KRGWKLQVTYNCRAPQSGTIQNQYLRMSLPNMGDPAHLASYGEFV-QVPGYP-YPAYVYY
880 890 900 910 920 930
340 350 360 370 380 390
KIAA10 PTYPVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPPPPPPPPSY
. . :::::::: .:: . :::.:::. . ::::::::::::::::::::::::
gi|989 TSPHMMTAWYPVGRDVHGRIIVVPVVITWSQNTNRQPPVPQYPPPQPPPPPPPPPPPPPP
940 950 960 970 980 990
400
KIAA10 STL
gi|989 PPASSCSAA
1000
>>gi|149064935|gb|EDM15011.1| rCG28175, isoform CRA_b [R (279 aa)
initn: 950 init1: 817 opt: 822 Z-score: 753.5 bits: 147.8 E(): 2.9e-33
Smith-Waterman score: 824; 65.217% identity (82.609% similar) in 184 aa overlap (46-228:1-167)
20 30 40 50 60 70
KIAA10 PGPAVEGPSATGPEIIRSPQDDASSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHE
:::::.::: ::::::::::::::::::..
gi|149 MLQIHIPGRPTLFVRAMIDSGASGNFIDQN
10 20 30
80 90 100 110 120 130
KIAA10 YVAQNGIPLRIKDWPILVEAIDGRPIASGPVVHETHDLIVDLGDHREVLSFDVTQSPFFP
.: ::.::::::.:::.::::::.::::::.. ::: ::::::::::.::::::::::::
gi|149 FVIQNAIPLRIKEWPIMVEAIDGHPIASGPIILETHHLIVDLGDHREILSFDVTQSPFFP
40 50 60 70 80 90
140 150 160 170 180 190
KIAA10 VVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYR
.:::.:::::::::::::.:::::.:.::: .::... ::: : :.:.:::. :
gi|149 IVLGIRWLSTHDPNITWSARSIVFNSDYCRLRCRVFAQIPPPLLFPVPHPPLH-P-----
100 110 120 130 140
200 210 220 230 240 250
KIAA10 VYQPVRYYYVQNVYTPVDEHVYPDHRL-VDPHIEMIPGAHSIPSGHVYSLSEPEMAALRD
::. ...::.:: : .. :..
gi|149 -----------NVHPNLQQHVHPDPFLSLQQHLQQRLHPEVQHYLQQHLHPQVLNYLQQC
150 160 170 180 190
260 270 280 290 300 310
KIAA10 FVARNVKDGLITPTIAPNGAQVLQVKRGWKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQ
gi|149 LQPELQHYLQHHLRPELQHYLQHHLHPELQHYLYHHLHSDMQHLLYPDPRNHPEPCHRPD
200 210 220 230 240 250
>>gi|80751092|tpe|CAI99872.1| TPA: pol-like protein [Mus (205 aa)
initn: 489 init1: 466 opt: 491 Z-score: 456.8 bits: 92.4 E(): 9.6e-17
Smith-Waterman score: 491; 44.444% identity (73.099% similar) in 171 aa overlap (1-168:22-189)
10 20 30
KIAA10 QLSCQGLKVFAGGKLPGPAVEGPSATGPEIIR--SPQDD
.: ::. . :::: ::::.: . :: : . ::.
gi|807 TGKTPRRPLVPLLWPSRSFCQRLPCQASSCPAGGKHGGPAVRGIPG-GP-IYKYASPSLP
10 20 30 40 50
40 50 60 70 80 90
KIAA10 AS-SPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAI
: : : . ..:.: ::. .: .::.:::. : ::. : .. ::.: . .:...:..
gi|807 ISMSRTLWLTVEIRL-GRRQFFEQAMVDSGSYRNSIDRSVVLREKIPIRNNIFPLMLETV
60 70 80 90 100 110
100 110 120 130 140 150
KIAA10 DGRPIASGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWSTRS
::::. .::...:: . : .:.: : :.::. ..: .:..::..:: :::::: ::::.
gi|807 DGRPLINGPITKETPPVEVKIGNHVEELQFDIIHAPRYPLILGIHWLETHDPNIEWSTRT
120 130 140 150 160 170
160 170 180 190 200 210
KIAA10 IVFDSEYCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYRVYQPVRYYYVQNVYTPVDEHV
. : :.::.:.:
gi|807 VSFPSHYCHYNCFRHRWNRRRRDEIIAG
180 190 200
>>gi|125855955|ref|XP_001338587.1| PREDICTED: similar to (1836 aa)
initn: 385 init1: 140 opt: 485 Z-score: 438.6 bits: 92.2 E(): 9.9e-16
Smith-Waterman score: 487; 33.333% identity (57.756% similar) in 303 aa overlap (10-304:253-543)
10 20 30
KIAA10 QLSCQGLKVFAGGKLPGPAVEGPSATGPEIIRSPQDDA-
: ... : : . . : . : . :. :
gi|125 LRIEVRLNRRHQRKLTRSSGRVEGTLSSSTFPAAHDPEPILPSKSQS-PPVKRGILVGAI
230 240 250 260 270 280
40 50 60 70 80 90
KIAA10 --SSPHLQVMLQIHLPGR-HTLFVRAMIDSGASGNFIDHEYVAQNGIP-LRIKDWPILVE
:: ...: . : : :..:::: :::.: ..: ::: . . : :: ..
gi|125 PLHSPSSRTLLPALIQYRGSTNACSALLDSGAEGNFMDSSVASQWGIPAIPLPD-PIPAR
290 300 310 320 330 340
100 110 120 130 140 150
KIAA10 AIDGRPIASGPVVHETHDL-IVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWS
..:: ::. . : : .. .: :.:::: .. . .:: :..:: :: : :.. ::
gi|125 SLDGTLIAT--ISHATPSVSLVISGNHREVTTLYLLDSPSAPIILGHPWLVQHGPHVDWS
350 360 370 380 390
160 170 180 190 200 210
KIAA10 TRSIVFDSEYCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYRVYQ-PVRYYYVQNVYTPV
:.. :. : : .:.: :. : . :.. . :..: . :..
gi|125 GNSVLSWSQSCLESCLGPAPFPVSVCP-------VFQVNAADLTGVPAEYRDLGLVFSKS
400 410 420 430 440 450
220 230 240 250 260 270
KIAA10 DEHVYPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTIAPN
: :: : ::..::. : :.::.:::: :: :. .. ...: ::: :. .:
gi|125 RATSLPPHRPYDCAIELLPGT-SPPKGHLYSLSSPEREAMDKYIDESLKAGLIRPSSSPA
460 470 480 490 500 510
280 290 300 310 320 330
KIAA10 GAQVLQVKR-GWKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQIPGYQ
:: . ::. .:. : :. :..::.:.::
gi|125 GAGFFFVKKKDGSLRPCIDYRGLNDITIKNRYPLPLMSSAFELLQGAQVFTKLDLRNAYH
520 530 540 550 560 570
340 350 360 370 380 390
KIAA10 TYPTYAAYPTYPVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPP
gi|125 LIRIREGDEWKTAFNTPTGHFEYRVLPFGLTNAPAVFQALVNDVLRDMVNQFVFVYLDDI
580 590 600 610 620 630
>>gi|189519150|ref|XP_001919628.1| PREDICTED: similar to (1217 aa)
initn: 341 init1: 174 opt: 481 Z-score: 437.4 bits: 91.4 E(): 1.2e-15
Smith-Waterman score: 482; 28.481% identity (57.911% similar) in 316 aa overlap (61-374:163-465)
40 50 60 70 80 90
KIAA10 IRSPQDDASSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWP
:::::::.:::::. ... ..::: :
gi|189 VSATTMFTTTNNVVNLPVTLRSNGDEIETMAMIDSGAAGNFIDYTFATTHSIPLTSYDSS
140 150 160 170 180 190
100 110 120 130 140
KIAA10 ILVEAIDGRPIASGPVVHETHDLIVDLGD-HREVLSFDVTQSPFFPVVLGVRWLSTHDPN
: . :.::::.. : . .: .... :. :.: .:. . .:: :.::. ::. :.:.
gi|189 IAITAVDGRPLGEGRIKFQTLPILLQTGSLHEEEISLLAINSPKHSVILGLPWLQQHNPQ
200 210 220 230 240 250
150 160 170 180 190 200
KIAA10 ITWSTRSIVFDSEYCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYRVYQPVRYYYVQNVY
..: : :. :. : .: :. : . :. . : :. . ...
gi|189 VSWRTGEITKWSNQCFTQC--LHPVSPVQINTINKTE-----DSELRHVPDAYHDLIEAF
260 270 280 290 300
210 220 230 240 250 260
KIAA10 TPVDEHVYPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTI
. : :: : ::..::. . : :... ::.:: :.......... :.: :.
gi|189 NKQKATKLPPHRENDCAIELLPGT-TPPRGRIFPLSQPETEAMKSYISEELEKGFIRPST
310 320 330 340 350 360
270 280 290 300 310 320
KIAA10 APNGAQVLQVKR-GWKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQIP
.: .: . ::. .:. :::. :..:.. .:: .: .: . : : .
gi|189 SPASAGFFFVKKKDGSLRPCIDCRGLNEITVKYRYPLPLVPAALEQLRSAQYFTKLDLRS
370 380 390 400 410 420
330 340 350 360 370 380
KIAA10 GYQTYPTYAAYPTYPVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPP
.:. . . .::. ::. . : .: .. .: ..
gi|189 AYNLIRIRQG-DEWKTGFSTI----DGHYEYLVMPFGLANSPSVFQAFVNEVFRDMLNKW
430 440 450 460 470
390 400
KIAA10 PPPPPPPPPSYSTL
gi|189 VIVYIDDILVYSNSLSEHIQHVRAVLKRLIQNQLYAKSSKCEFHQTCISFLGYIISPEGV
480 490 500 510 520 530
402 residues in 1 query sequences
2693465022 residues in 7827732 library sequences
Tcomplib [34.26] (8 proc)
start: Tue Mar 3 15:50:06 2009 done: Tue Mar 3 15:54:45 2009
Total Scan time: 1464.600 Total Display time: 0.160
Function used was FASTA [version 34.26.5 April 26, 2007]