# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/fh03989.fasta.huge -Q ../query/KIAA1044.ptfa ./tmplib.24314 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 KIAA1044, 646 aa
 vs ./tmplib.24314 library

1986859 residues in  2037 sequences
  Expectation_n fit: rho(ln(x))= 5.0379+/-0.00485; mu= 14.7644+/- 0.331
 mean_var=96.2834+/-23.107, 0's: 0 Z-trim: 5  B-trim: 0 in 0/40
 Lambda= 0.130707

FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 38, opt: 26, open/ext: -10/-2, width:  16
The best scores are:                                      opt bits E(2037)
KIAA1144  ( 489 res)   hj05565                     ( 489)  541 112.5 9.1e-26
KIAA0176  ( 265 res)   ha03941                     ( 265)  160 40.3 0.00026


>>KIAA1144  ( 489 res)   hj05565                          (489 aa)
 initn: 654 init1: 225 opt: 541  Z-score: 554.5  bits: 112.5 E(): 9.1e-26
Smith-Waterman score: 731;  30.323% identity (64.301% similar) in 465 aa overlap (55-479:27-481)

           30        40        50        60        70        80    
KIAA10 LPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLG
                                     .:. : .::.: . .  . :: :.:.: ::
KIAA11     RPRAARAAGASSMTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLG
                   10        20        30        40        50      

               90             100       110       120       130    
KIAA10 S----SERDFF------YHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEE
              :. .      :    ....:::.:..: ..:.::.:::::   . :. ....:
KIAA11 RLLLCHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQE
         60        70        80        90       100       110      

          140       150        160       170                       
KIAA10 LAFFGLIPEIIGDCCYEEYKDRRRE-NAERLQDDADTDTAGES---------------AL
       . ..:.   .: .::   :. :. : . :. ....: ...  :               . 
KIAA11 IEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQ
        120       130       140       150       160       170      

      180       190       200       210       220          230     
KIAA10 PTMTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVP---CGSSPGHIKEL
       :  . :...: :..::  :... ::  .. . .  :.:.  ....:     .: :.  : 
KIAA11 PLGNFRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGED
        180       190       200       210       220       230      

         240       250       260       270       280       290     
KIAA10 PCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVM
       :   :. .    ..   .  :: : . :.:.::.  .: ......::...:.:.:: ::.
KIAA11 P---RFEI----VEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVV
           240           250       260       270       280         

         300              310       320       330       340        
KIAA10 TDNEDVSGAFVTL-------RVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLT
       .   . . ....:       :..:.:::.:..::: ::: :: :::   .:.:.::. :.
KIAA11 NLVVESTPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLS
     290       300       310       320       330       340         

      350       360       370       380       390       400        
KIAA10 MAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSL
       ..: ::..: .  ::  . . ...::: .:.. :.:::.::::.:: : :::. .: : :
KIAA11 VGISIFSVVAYTIEKEENEG-LATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACIL
     350       360        370       380       390       400        

      410       420       430       440        450       460       
KIAA10 SGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLAR-IRAAKSGSANAYMQSKRNG
       .:.::..::. .: ..::..:..... ..  :...  ..  .. . : .   :.  : ..
KIAA11 AGILVVVLPITLIFNKFSHFYRRQKQLES--AMRSCDFGDGMKEVPSVNLRDYYAHKVKS
      410       420       430         440       450       460      

          470       480       490       500       510       520    
KIAA10 L---LSNQLQSSEDEQAFVSKSGSSFETQHHHLLHCLEKTTNHEFVDEQVFEESCMEVAT
       :   :.:. .:: .:                                             
KIAA11 LMASLTNMSRSSPSELSLNDSLR                                     
        470       480                                              

>>KIAA0176  ( 265 res)   ha03941                          (265 aa)
 initn: 168 init1:  95 opt: 160  Z-score: 169.4  bits: 40.3 E(): 0.00026
Smith-Waterman score: 160;  31.496% identity (51.969% similar) in 127 aa overlap (42-163:59-179)

              20        30        40        50        60        70 
KIAA10 PLQVIMAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTW
                                     : :.::..         . :::.:: : : 
KIAA01 PVRGPPSPRPAGPTPRGHGRPAAAVAQRLEPGPGPPERAGGGGAARWVRLNVGGTYFVTT
       30        40        50        60        70        80        

              80          90          100       110       120      
KIAA10 QDTLERYPDTLLGS--SERDFFY---HPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHE
       ..:: : : ..:     ..:      . ::  :..::::  :  :::. : :::   .. 
KIAA01 RQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKEL
       90       100       110       120       130       140        

        130       140       150       160       170       180      
KIAA10 CISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQR
          .  ::  :...   .      .  :.: :.: .:                       
KIAA01 AEEGVLEEAEFYNIASLV------RLVKERIRDNENRTSQGPVKHVYRVLQCQEEELTQM
      150       160             170       180       190       200  

        190       200       210       220       230       240      
KIAA10 VWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFF
                                                                   
KIAA01 VSTMSDGWKFEQLISIGSSYNYGNEDQAEFLCVVSRELNNSTNGIVIEPSEKAKILQERG
            210       220       230       240       250       260  




646 residues in 1 query   sequences
1986859 residues in 2037 library sequences
 Scomplib [34.26]
 start: Thu Dec 18 15:06:57 2008 done: Thu Dec 18 15:06:58 2008
 Total Scan time:  0.520 Total Display time:  0.020

Function used was FASTA [version 34.26.5 April 26, 2007]