# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/fh00114.fasta.nr -Q ../query/KIAA1026.ptfa /cdna2/lib/nr/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
KIAA1026, 519 aa
vs /cdna2/lib/nr/nr library
2693465022 residues in 7827732 sequences
statistics sampled from 60000 to 7819348 sequences
Expectation_n fit: rho(ln(x))= 6.2017+/-0.000205; mu= 8.7833+/- 0.011
mean_var=132.3152+/-25.515, 0's: 38 Z-trim: 58 B-trim: 599 in 2/64
Lambda= 0.111499
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 37, opt: 25, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7827732)
gi|168269626|dbj|BAG09940.1| kazrin protein [synth ( 421) 2764 455.7 1.1e-125
gi|46276354|gb|AAS86434.1| kazrin isoform A [Homo ( 421) 2237 371.0 3.6e-100
gi|172044653|sp|Q674X7.2|KAZRN_HUMAN RecName: Full ( 775) 2237 371.2 5.5e-100
gi|182705232|sp|Q5FWS6.2|KAZRN_RAT RecName: Full=K ( 780) 2114 351.5 5e-94
gi|157837990|ref|NP_001103154.1| kazrin isoform 2 ( 425) 2100 348.9 1.6e-93
gi|187595283|sp|Q69ZS8.2|KAZRN_MOUSE RecName: Full ( 779) 2100 349.2 2.4e-93
gi|134026164|gb|AAI35240.1| Kaz protein [Xenopus t ( 409) 1811 302.4 1.5e-79
gi|46276356|gb|AAS86435.1| kazrin isoform B [Homo ( 415) 1780 297.5 4.8e-78
gi|119572091|gb|EAW51706.1| hCG1821267, isoform CR ( 769) 1780 297.7 7.4e-78
gi|194208027|ref|XP_001489243.2| PREDICTED: simila ( 775) 1765 295.3 4e-77
gi|194674171|ref|XP_587895.4| PREDICTED: similar t ( 787) 1757 294.0 9.8e-77
gi|149024540|gb|EDL81037.1| rCG30577 [Rattus norve ( 415) 1737 290.5 5.9e-76
gi|122889986|emb|CAM13390.1| novel protein (903040 ( 414) 1723 288.3 2.8e-75
gi|148681475|gb|EDL13422.1| mCG19998 [Mus musculus ( 414) 1720 287.8 3.9e-75
gi|26342997|dbj|BAC35155.1| unnamed protein produc ( 414) 1717 287.3 5.4e-75
gi|220939462|emb|CAM13393.2| novel protein (903040 ( 698) 1712 286.7 1.4e-74
gi|118101163|ref|XP_423873.2| PREDICTED: similar t ( 376) 1688 282.6 1.3e-73
gi|46276358|gb|AAS86436.1| kazrin isoform C [Homo ( 327) 1649 276.3 9.1e-72
gi|119572088|gb|EAW51703.1| hCG1821267, isoform CR ( 681) 1649 276.6 1.5e-71
gi|58402693|gb|AAH89223.1| Similar to CG11206-PA [ ( 327) 1630 273.2 7.5e-71
gi|18605758|gb|AAH22941.1| 9030409G11Rik protein [ ( 326) 1616 271.0 3.6e-70
gi|6526769|dbj|BAA88115.1| HRIHFB2003 [Homo sapien ( 261) 1535 257.8 2.6e-66
gi|220939463|emb|CAX15670.1| novel protein (903040 ( 261) 1519 255.3 1.5e-65
gi|118763895|gb|AAI28837.1| Zgc:158299 [Danio reri ( 430) 1491 251.0 4.9e-64
gi|47229821|emb|CAG07017.1| unnamed protein produc ( 540) 1452 244.8 4.4e-62
gi|73950749|ref|XP_849054.1| PREDICTED: similar to ( 918) 1194 203.5 2e-49
gi|172048413|sp|A9C3W3.1|KAZRA_DANRE RecName: Full ( 786) 1158 197.7 9.9e-48
gi|166865098|gb|ABZ01809.1| kazrin [Xenopus (Silur ( 437) 1129 192.8 1.7e-46
gi|168983978|emb|CAQ06786.1| kazrin [Homo sapiens] ( 166) 1021 175.0 1.5e-41
gi|46249653|gb|AAH68939.1| MGC83192 protein [Xenop ( 380) 927 160.2 9.2e-37
gi|47220398|emb|CAG03178.1| unnamed protein produc ( 437) 891 154.5 5.6e-35
gi|26328279|dbj|BAC27880.1| unnamed protein produc ( 542) 779 136.6 1.7e-29
gi|210108729|gb|EEA56619.1| hypothetical protein B ( 969) 514 94.2 1.8e-16
gi|210083682|gb|EEA32267.1| hypothetical protein B (1025) 514 94.2 1.8e-16
gi|90078544|dbj|BAE88952.1| unnamed protein produc ( 115) 463 85.0 1.2e-14
gi|212508698|gb|EEB12311.1| Liprin-beta-2, putativ (1046) 410 77.5 2e-11
gi|189235614|ref|XP_969578.2| PREDICTED: similar t ( 895) 404 76.5 3.5e-11
gi|115700871|ref|XP_001191434.1| PREDICTED: hypoth ( 627) 384 73.1 2.6e-10
gi|156221552|gb|EDO42406.1| predicted protein [Nem ( 253) 369 70.3 7.3e-10
gi|156551447|ref|XP_001604567.1| PREDICTED: simila ( 933) 365 70.2 2.8e-09
gi|110766885|ref|XP_393210.3| PREDICTED: similar t ( 900) 348 67.4 1.8e-08
gi|33589392|gb|AAQ22463.1| RE35867p [Drosophila me ( 653) 339 65.9 4e-08
gi|190658376|gb|EDV55589.1| GG20699 [Drosophila er (1172) 342 66.6 4.3e-08
gi|167868050|gb|EDS31433.1| conserved hypothetical ( 785) 339 65.9 4.5e-08
gi|157400455|gb|ABV53883.1| CG11206, isoform D [Dr ( 852) 339 66.0 4.8e-08
gi|157400452|gb|AAF46835.2| CG11206, isoform A [Dr (1023) 339 66.1 5.4e-08
gi|190621045|gb|EDV36569.1| GF13024 [Drosophila an (1134) 339 66.1 5.8e-08
gi|157400454|gb|ABV53882.1| CG11206, isoform C [Dr (1152) 339 66.1 5.9e-08
gi|194178510|gb|EDW92121.1| GE11683 [Drosophila ya (1163) 339 66.1 5.9e-08
gi|194194615|gb|EDX08191.1| GD25133 [Drosophila si (1015) 338 65.9 6e-08
>>gi|168269626|dbj|BAG09940.1| kazrin protein [synthetic (421 aa)
initn: 2764 init1: 2764 opt: 2764 Z-score: 2412.7 bits: 455.7 E(): 1.1e-125
Smith-Waterman score: 2764; 100.000% identity (100.000% similar) in 421 aa overlap (99-519:1-421)
70 80 90 100 110 120
KIAA10 QVEPGVPGRAPPAHHAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAEL
::::::::::::::::::::::::::::::
gi|168 MMEDNKQLALRIDGAVQSASQEVTNLRAEL
10 20 30
130 140 150 160 170 180
KIAA10 TATNRRLAELSGGGGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSRLQEEVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 TATNRRLAELSGGGGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSRLQEEVH
40 50 60 70 80 90
190 200 210 220 230 240
KIAA10 LLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 LLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG
100 110 120 130 140 150
250 260 270 280 290 300
KIAA10 EKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 EKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR
160 170 180 190 200 210
310 320 330 340 350 360
KIAA10 QAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 QAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNG
220 230 240 250 260 270
370 380 390 400 410 420
KIAA10 NQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 NQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDR
280 290 300 310 320 330
430 440 450 460 470 480
KIAA10 SSTPSDINSPRHRTHSLCNVRPAAAGPGPLGPAQKLQGRGWRGEAILAVSSRPPREHSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 SSTPSDINSPRHRTHSLCNVRPAAAGPGPLGPAQKLQGRGWRGEAILAVSSRPPREHSGE
340 350 360 370 380 390
490 500 510
KIAA10 CISCSVLSFCKKRWMWGEKGMRPVCSLCPGG
:::::::::::::::::::::::::::::::
gi|168 CISCSVLSFCKKRWMWGEKGMRPVCSLCPGG
400 410 420
>>gi|46276354|gb|AAS86434.1| kazrin isoform A [Homo sapi (421 aa)
initn: 2223 init1: 2223 opt: 2237 Z-score: 1954.5 bits: 371.0 E(): 3.6e-100
Smith-Waterman score: 2237; 97.260% identity (97.808% similar) in 365 aa overlap (99-463:1-358)
70 80 90 100 110 120
KIAA10 QVEPGVPGRAPPAHHAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAEL
::::::::::::::::::::::::::::::
gi|462 MMEDNKQLALRIDGAVQSASQEVTNLRAEL
10 20 30
130 140 150 160 170 180
KIAA10 TATNRRLAELSGGGGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSRLQEEVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|462 TATNRRLAELSGGGGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSRLQEEVH
40 50 60 70 80 90
190 200 210 220 230 240
KIAA10 LLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|462 LLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG
100 110 120 130 140 150
250 260 270 280 290 300
KIAA10 EKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|462 EKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR
160 170 180 190 200 210
310 320 330 340 350 360
KIAA10 QAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|462 QAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNG
220 230 240 250 260 270
370 380 390 400 410 420
KIAA10 NQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|462 NQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDR
280 290 300 310 320 330
430 440 450 460 470 480
KIAA10 SSTPSDINSPRHRTHSLCNVRPAAAGPGPLGPAQKLQGRGWRGEAILAVSSRPPREHSGE
::::::::::::::::::: : .: ::.::
gi|462 SSTPSDINSPRHRTHSLCN------GDSP-GPVQKNLHNPIVQSLEDLEDQKRKKKKEKM
340 350 360 370 380
490 500 510
KIAA10 CISCSVLSFCKKRWMWGEKGMRPVCSLCPGG
gi|462 GFGSISRVFARGKQRKSLDPGLFDGTAPDYYIEEDADW
390 400 410 420
>>gi|172044653|sp|Q674X7.2|KAZRN_HUMAN RecName: Full=Kaz (775 aa)
initn: 2223 init1: 2223 opt: 2237 Z-score: 1951.2 bits: 371.2 E(): 5.5e-100
Smith-Waterman score: 2237; 97.260% identity (97.808% similar) in 365 aa overlap (99-463:1-358)
70 80 90 100 110 120
KIAA10 QVEPGVPGRAPPAHHAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAEL
::::::::::::::::::::::::::::::
gi|172 MMEDNKQLALRIDGAVQSASQEVTNLRAEL
10 20 30
130 140 150 160 170 180
KIAA10 TATNRRLAELSGGGGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSRLQEEVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|172 TATNRRLAELSGGGGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSRLQEEVH
40 50 60 70 80 90
190 200 210 220 230 240
KIAA10 LLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|172 LLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG
100 110 120 130 140 150
250 260 270 280 290 300
KIAA10 EKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|172 EKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR
160 170 180 190 200 210
310 320 330 340 350 360
KIAA10 QAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|172 QAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNG
220 230 240 250 260 270
370 380 390 400 410 420
KIAA10 NQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|172 NQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDR
280 290 300 310 320 330
430 440 450 460 470 480
KIAA10 SSTPSDINSPRHRTHSLCNVRPAAAGPGPLGPAQKLQGRGWRGEAILAVSSRPPREHSGE
::::::::::::::::::: : .: ::.::
gi|172 SSTPSDINSPRHRTHSLCN------GDSP-GPVQKNLHNPIVQSLEDLEDQKRKKKKEKM
340 350 360 370 380
490 500 510
KIAA10 CISCSVLSFCKKRWMWGEKGMRPVCSLCPGG
gi|172 GFGSISRVFARGKQRKSLDPGLFDDSDSQCSPTRQSLSLSEGEEQMDRLQQVELVRTTPM
390 400 410 420 430 440
>>gi|182705232|sp|Q5FWS6.2|KAZRN_RAT RecName: Full=Kazri (780 aa)
initn: 1824 init1: 1824 opt: 2114 Z-score: 1844.3 bits: 351.5 E(): 5e-94
Smith-Waterman score: 2114; 92.162% identity (95.135% similar) in 370 aa overlap (99-463:1-363)
70 80 90 100 110 120
KIAA10 QVEPGVPGRAPPAHHAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAEL
::::::::::::::::::::::::::::::
gi|182 MMEDNKQLALRIDGAVQSASQEVTNLRAEL
10 20 30
130 140 150 160 170 180
KIAA10 TATNRRLAELSGGGG-PGPGPGAAASASAAG----DSAATNMENPQLGAQVLLREEVSRL
::::::::::::::: :: :::::.:::::. :::...::: : :::::::::: .:
gi|182 TATNRRLAELSGGGGGPGSGPGAATSASAAAVTVADSAVATMENHQHGAQVLLREEVVQL
40 50 60 70 80 90
190 200 210 220 230 240
KIAA10 QEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADR
::::::::::::::::::::::::: :::::::::::::.:::::::::.::::::::::
gi|182 QEEVHLLRQMKEMLAKDLEESQGGKCSEVLSATELRVQLVQKEQELARAREALQAMKADR
100 110 120 130 140 150
250 260 270 280 290 300
KIAA10 KRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|182 KRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREK
160 170 180 190 200 210
310 320 330 340 350 360
KIAA10 WELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGE
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
gi|182 WELRRQAKEATDHAAALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGE
220 230 240 250 260 270
370 380 390 400 410 420
KIAA10 TVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|182 TVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASA
280 290 300 310 320 330
430 440 450 460 470 480
KIAA10 AEGDRSSTPSDINSPRHRTHSLCNVRPAAAGPGPLGPAQKLQGRGWRGEAILAVSSRPPR
:::::::::::::::::::::::: : .: ::.::
gi|182 AEGDRSSTPSDINSPRHRTHSLCN------GDSP-GPVQKSLHNPIVQSLEDLEDQKRKK
340 350 360 370 380
490 500 510
KIAA10 EHSGECISCSVLSFCKKRWMWGEKGMRPVCSLCPGG
gi|182 KKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCSPTRHSLSLSEGEEQMDRLQHVELV
390 400 410 420 430 440
>>gi|157837990|ref|NP_001103154.1| kazrin isoform 2 [Mus (425 aa)
initn: 1808 init1: 1527 opt: 2100 Z-score: 1835.4 bits: 348.9 E(): 1.6e-93
Smith-Waterman score: 2100; 92.162% identity (94.865% similar) in 370 aa overlap (99-463:1-362)
70 80 90 100 110 120
KIAA10 QVEPGVPGRAPPAHHAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAEL
::::::::::::::::::::::::::::::
gi|157 MMEDNKQLALRIDGAVQSASQEVTNLRAEL
10 20 30
130 140 150 160 170 180
KIAA10 TATNRRLAELSGGGG-PGPGPGAAASASAAG----DSAATNMENPQLGAQVLLREEVSRL
::::::::::::::: :: :::::.:::::. :::...::: : :::::::::: .:
gi|157 TATNRRLAELSGGGGGPGSGPGAATSASAAAVTVADSAVATMENHQHGAQVLLREEVVQL
40 50 60 70 80 90
190 200 210 220 230 240
KIAA10 QEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADR
::::::::::::::::::::::::: :::::::::::::.::::::::::::::::::::
gi|157 QEEVHLLRQMKEMLAKDLEESQGGKCSEVLSATELRVQLVQKEQELARAKEALQAMKADR
100 110 120 130 140 150
250 260 270 280 290 300
KIAA10 KRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|157 KRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREK
160 170 180 190 200 210
310 320 330 340 350 360
KIAA10 WELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGE
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
gi|157 WELRRQAKEATDHAAALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGE
220 230 240 250 260 270
370 380 390 400 410 420
KIAA10 TVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASA
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
gi|157 TVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQ-VRVSPCHSRQPSVISDASA
280 290 300 310 320
430 440 450 460 470 480
KIAA10 AEGDRSSTPSDINSPRHRTHSLCNVRPAAAGPGPLGPAQKLQGRGWRGEAILAVSSRPPR
:::::::::::::::::::::::: : .: ::.::
gi|157 AEGDRSSTPSDINSPRHRTHSLCN------GDSP-GPVQKSLHNPIVQSLEDLEDQKRKK
330 340 350 360 370 380
490 500 510
KIAA10 EHSGECISCSVLSFCKKRWMWGEKGMRPVCSLCPGG
gi|157 KKEKMGFGSISRVFARGKQRKSLDPGLFDGTAPDYYIEEDADW
390 400 410 420
>>gi|187595283|sp|Q69ZS8.2|KAZRN_MOUSE RecName: Full=Kaz (779 aa)
initn: 1808 init1: 1527 opt: 2100 Z-score: 1832.1 bits: 349.2 E(): 2.4e-93
Smith-Waterman score: 2100; 92.162% identity (94.865% similar) in 370 aa overlap (99-463:1-362)
70 80 90 100 110 120
KIAA10 QVEPGVPGRAPPAHHAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAEL
::::::::::::::::::::::::::::::
gi|187 MMEDNKQLALRIDGAVQSASQEVTNLRAEL
10 20 30
130 140 150 160 170 180
KIAA10 TATNRRLAELSGGGG-PGPGPGAAASASAAG----DSAATNMENPQLGAQVLLREEVSRL
::::::::::::::: :: :::::.:::::. :::...::: : :::::::::: .:
gi|187 TATNRRLAELSGGGGGPGSGPGAATSASAAAVTVADSAVATMENHQHGAQVLLREEVVQL
40 50 60 70 80 90
190 200 210 220 230 240
KIAA10 QEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADR
::::::::::::::::::::::::: :::::::::::::.::::::::::::::::::::
gi|187 QEEVHLLRQMKEMLAKDLEESQGGKCSEVLSATELRVQLVQKEQELARAKEALQAMKADR
100 110 120 130 140 150
250 260 270 280 290 300
KIAA10 KRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|187 KRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREK
160 170 180 190 200 210
310 320 330 340 350 360
KIAA10 WELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGE
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
gi|187 WELRRQAKEATDHAAALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGE
220 230 240 250 260 270
370 380 390 400 410 420
KIAA10 TVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASA
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
gi|187 TVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQ-VRVSPCHSRQPSVISDASA
280 290 300 310 320
430 440 450 460 470 480
KIAA10 AEGDRSSTPSDINSPRHRTHSLCNVRPAAAGPGPLGPAQKLQGRGWRGEAILAVSSRPPR
:::::::::::::::::::::::: : .: ::.::
gi|187 AEGDRSSTPSDINSPRHRTHSLCN------GDSP-GPVQKSLHNPIVQSLEDLEDQKRKK
330 340 350 360 370 380
490 500 510
KIAA10 EHSGECISCSVLSFCKKRWMWGEKGMRPVCSLCPGG
gi|187 KKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCSPTRHSLSLSEGEEQMDRLQHVELV
390 400 410 420 430 440
>>gi|134026164|gb|AAI35240.1| Kaz protein [Xenopus tropi (409 aa)
initn: 1833 init1: 1609 opt: 1811 Z-score: 1584.3 bits: 302.4 E(): 1.5e-79
Smith-Waterman score: 1811; 82.254% identity (91.549% similar) in 355 aa overlap (99-447:1-354)
70 80 90 100 110 120
KIAA10 QVEPGVPGRAPPAHHAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAEL
:::::::::::::::.::::::::::::::
gi|134 MMEDNKQLALRIDGAIQSASQEVTNLRAEL
10 20 30
130 140 150 160 170 180
KIAA10 TATNRRLAELSGG------GGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSR
::::::::::... .. : . . :.. .:.. .. .:::::::.
gi|134 TATNRRLAELNSADPCVMENNQHNTQGMEYGKMKLSRSGTLQMQEKYTNG-LLLREEVSQ
40 50 60 70 80
190 200 210 220 230 240
KIAA10 LQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKAD
::.:::::::::::::::::::. .:.::::.:::.:::::::::: ::::::::::::
gi|134 LQDEVHLLRQMKEMLAKDLEESHDCRSAEVLSVTELKVQLAQKEQELERAKEALQAMKAD
90 100 110 120 130 140
250 260 270 280 290 300
KIAA10 RKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLERE
::::: :::::::::.:::.:::::::::::::::::::::::::::::::::::.::::
gi|134 RKRLKTEKTDLVSQMEQLYTTLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDVLERE
150 160 170 180 190 200
310 320 330 340 350 360
KIAA10 KWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPG
:::::::::::::::..:::::::::::.:::::::::::::::::::::::::::::::
gi|134 KWELRRQAKEATDHASSLRSQLDLKDNRIKELEAELAMAKQSLATLTKDVPKRHSLAMPG
210 220 230 240 250 260
370 380 390 400 410 420
KIAA10 ETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDAS
:::::::::::..::::::::::::::::::.:: : .::::::::::::::::::::::
gi|134 ETVLNGNQEWVMHADLPLTAAIRQSQQTLYHGHPQHTTDRQAVRVSPCHSRQPSVISDAS
270 280 290 300 310 320
430 440 450 460 470 480
KIAA10 AAEGDRSSTPSDINSPRHRTHSLCNVRPAAAGPGPLGPAQKLQGRGWRGEAILAVSSRPP
:::::::::::::::::::::::::
gi|134 AAEGDRSSTPSDINSPRHRTHSLCNSLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSL
330 340 350 360 370 380
>>gi|46276356|gb|AAS86435.1| kazrin isoform B [Homo sapi (415 aa)
initn: 1783 init1: 1749 opt: 1780 Z-score: 1557.3 bits: 297.5 E(): 4.8e-78
Smith-Waterman score: 1793; 83.056% identity (88.611% similar) in 360 aa overlap (113-463:3-352)
90 100 110 120 130 140
KIAA10 HAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSGGG
:..:.: : .: .:.: .. ..:.
gi|462 MRAADSGSWE--RVR-QLAAQGEPAPSCGAGA
10 20
150 160 170 180 190
KIAA10 GPGPGPGAAAS---ASAAGDSAATNMENPQLGAQ------VLLREEVSRLQEEVHLLRQM
::. :: :: ..::: . :.. :. ::::::::::::::::::::
gi|462 GPARPPGPAACEQCVDAAGPGDRPRAGVPRVRADGDCSQPVLLREEVSRLQEEVHLLRQM
30 40 50 60 70 80
200 210 220 230 240 250
KIAA10 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|462 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL
90 100 110 120 130 140
260 270 280 290 300 310
KIAA10 VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|462 VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA
150 160 170 180 190 200
320 330 340 350 360 370
KIAA10 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|462 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWV
210 220 230 240 250 260
380 390 400 410 420 430
KIAA10 VQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|462 VQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPS
270 280 290 300 310 320
440 450 460 470 480 490
KIAA10 DINSPRHRTHSLCNVRPAAAGPGPLGPAQKLQGRGWRGEAILAVSSRPPREHSGECISCS
:::::::::::::: : .: ::.::
gi|462 DINSPRHRTHSLCN------GDSP-GPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSI
330 340 350 360 370 380
>>gi|119572091|gb|EAW51706.1| hCG1821267, isoform CRA_c (769 aa)
initn: 1783 init1: 1749 opt: 1780 Z-score: 1554.0 bits: 297.7 E(): 7.4e-78
Smith-Waterman score: 1793; 83.056% identity (88.611% similar) in 360 aa overlap (113-463:3-352)
90 100 110 120 130 140
KIAA10 HAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSGGG
:..:.: : .: .:.: .. ..:.
gi|119 MRAADSGSWE--RVR-QLAAQGEPAPSCGAGA
10 20
150 160 170 180 190
KIAA10 GPGPGPGAAAS---ASAAGDSAATNMENPQLGAQ------VLLREEVSRLQEEVHLLRQM
::. :: :: ..::: . :.. :. ::::::::::::::::::::
gi|119 GPARPPGPAACEQCVDAAGPGDRPRAGVPRVRADGDCSQPVLLREEVSRLQEEVHLLRQM
30 40 50 60 70 80
200 210 220 230 240 250
KIAA10 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL
90 100 110 120 130 140
260 270 280 290 300 310
KIAA10 VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA
150 160 170 180 190 200
320 330 340 350 360 370
KIAA10 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWV
210 220 230 240 250 260
380 390 400 410 420 430
KIAA10 VQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPS
270 280 290 300 310 320
440 450 460 470 480 490
KIAA10 DINSPRHRTHSLCNVRPAAAGPGPLGPAQKLQGRGWRGEAILAVSSRPPREHSGECISCS
:::::::::::::: : .: ::.::
gi|119 DINSPRHRTHSLCN------GDSP-GPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSI
330 340 350 360 370 380
>>gi|194208027|ref|XP_001489243.2| PREDICTED: similar to (775 aa)
initn: 1805 init1: 1744 opt: 1765 Z-score: 1540.9 bits: 295.3 E(): 4e-77
Smith-Waterman score: 1765; 94.949% identity (95.960% similar) in 297 aa overlap (168-463:69-358)
140 150 160 170 180 190
KIAA10 LSGGGGPGPGPGAAASASAAGDSAATNMENPQLG-AQVLLREEVSRLQEEVHLLRQMKEM
: :: :::::::::::::::::::::::
gi|194 LQVLVAAEVQAAECGRYSPPPGAPGPEGRCPLLGLIPVLLREEVSRLQEEVHLLRQMKEM
40 50 60 70 80 90
200 210 220 230 240 250
KIAA10 LAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQ
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LTKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQ
100 110 120 130 140 150
260 270 280 290 300 310
KIAA10 MQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 MQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDH
160 170 180 190 200 210
320 330 340 350 360 370
KIAA10 ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQA
220 230 240 250 260 270
380 390 400 410 420 430
KIAA10 DLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPSDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 DLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPSDIN
280 290 300 310 320 330
440 450 460 470 480 490
KIAA10 SPRHRTHSLCNVRPAAAGPGPLGPAQKLQGRGWRGEAILAVSSRPPREHSGECISCSVLS
::::::::::: : .: ::.::
gi|194 SPRHRTHSLCN------GDSP-GPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRV
340 350 360 370 380 390
519 residues in 1 query sequences
2693465022 residues in 7827732 library sequences
Tcomplib [34.26] (8 proc)
start: Tue Mar 3 14:03:46 2009 done: Tue Mar 3 14:08:02 2009
Total Scan time: 1582.780 Total Display time: 0.150
Function used was FASTA [version 34.26.5 April 26, 2007]