hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-17442251/chunk_1/iprscan-20080502-17442251.nocrc
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Query sequence: KIAA0951
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
PF00135.18.fs Carboxylesterase                             570.7   1.3e-168   1
PF00135.18.ls Carboxylesterase                             452.2   6.2e-133   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
PF00135.18.ls   1/1       1   453 [.     1   592 []   452.2 6.2e-133
PF00135.18.fs   1/1      26   453 ..   140   592 .]   570.7 1.3e-168

Alignments of top-scoring domains:
PF00135.18.ls: domain 1 of 1, from 1 to 453: score 452.2, E = 6.2e-133
                   *->mllllllllllllflavvataptspedpvVeTsyvgGkvrGlrvkvd
                                        +t                   r      d
    KIAA0951     1    ------------------GT----------------NIKRN----AD 9    

                   ggnkpvyaFlGIPYAkPPvGeLRFkkPqPpepWtgvldATkygpaCpQnd
                   +                                               + 
    KIAA0951    10 D-----------------------------------------------IT 12   

                   lgfpgfslalhvgsemwnkntgksmSEDCLYLNVytPklasenkklPVmV
                                     +n      ED        ++  + n+k PVmV
    KIAA0951    13 ------------------SNDH---GED--------KDIHEQNSKKPVMV 33   

                   wIHGGGFqsGsassvslddydgpdlaasedVVVVtiNYRLGalGFLstgd
                   +IHGG +++G++     ++ dg++la++++V+V+tiNYRLG+lGFLstgd
    KIAA0951    34 YIHGGSYMEGTG-----NMIDGSILASYGNVIVITINYRLGILGFLSTGD 78   

                   selppppGNaGLlDQvlALrWVqeNIaaFGGDPdnVTlFGeSAGAaSVsl
                   + ++   GN+GLlDQ++ALrW+ eN+ aFGGDP++VT+FG +AGA++Vsl
    KIAA0951    79 QAAK---GNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSL 125  

                   lllSppqsrGLFhrAIlqSGsalspwaitsppearnrakrlAkllGCpge
                   l+lS  +s+GLF++AI+qSG+als+wa++++p   ++++ lA ++GC++ 
    KIAA0951   126 LTLS-HYSEGLFQKAIIQSGTALSSWAVNYQP--AKYTRILADKVGCNML 172  

                   dseelveCLRkksaeelldaqwklllleefgffplfpFgPVvdGdtpdaf
                   d +++veCL++k+ +el+ ++    ++++   f      PV+dGd    +
    KIAA0951   173 DTTDMVECLKNKNYKELIQQTI--TPATYHIAFG-----PVIDGD----V 211  

                   lpkdPeellkegnfnkvPlliGvtsdEGllflayvl.dp.lsadllseid
                   +p+dP++l+++g+f ++++++Gv++ EGl f+  + ++++ +       d
    KIAA0951   212 IPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVdNEdGV----TPND 257  

                   nedlflellpellpgase.steklreeiadaikeeYtdddd.nseesrrd
                   +++   +++ ++l+g++e++     + ++++ik++Ytd++d+ ++e+rr+
    KIAA0951   258 FDF-SVSNFVDNLYGYPEgK-----DTLRETIKFMYTDWADkENPETRRK 301  

                   alldllsDylFvcPilrlalaraakagspvYlYrFdyrssdsfnqyrinl
                    l+ l++D+++v+P +++ ++ +a++gsp+Y+Y F +++          +
    KIAA0951   302 TLVALFTDHQWVAP-AVATADLHAQYGSPTYFYAFYHHCQ--------SE 342  

                   lwppwrgvsHgdelsYvFGnpls.k.ly....sseeeemlssrrmmrywt
                   ++p w    Hgde++YvFG p++++++  + ++s+ ++mls +++m+ywt
    KIAA0951   343 MKPSWADSAHGDEVPYVFGIPMIgPtELfscnFSKNDVMLS-AVVMTYWT 391  

                   nFAktGnPN.............ngessglvkWppytkeeqkyylpitlln
                   nFAktG+PN++ +++++  +++++  +++v W +y++++q  yl+i+l++
    KIAA0951   392 NFAKTGDPNqpvpqdtkfihtkPNR-FEEVAWSKYNPKDQ-LYLHIGLKP 439  

                   itqk.lreedPrkvkcafw<-*
                   ++++++r+++     +afw   
    KIAA0951   440 RVRDhYRATK-----VAFW    453  

PF00135.18.fs: domain 1 of 1, from 26 to 453: score 570.7, E = 1.3e-168
                   *->nkklPVmVwIHGGGFqsGsassvslddydgpdlaasedVVVVtiNYR
                      n+k PVmV+IHGG +++G++     ++ dg++la++++V+V+tiNYR
    KIAA0951    26    NSKKPVMVYIHGGSYMEGTG-----NMIDGSILASYGNVIVITINYR 67   

                   LGalGFLstgdselppppGNaGLlDQvlALrWVqeNIaaFGGDPdnVTlF
                   LG+lGFLstgd+ ++   GN+GLlDQ++ALrW+ eN+ aFGGDP++VT+F
    KIAA0951    68 LGILGFLSTGDQAAK---GNYGLLDQIQALRWIEENVGAFGGDPKRVTIF 114  

                   GeSAGAaSVsllllSppqsrGLFhrAIlqSGsalspwaitsppearnrak
                   G +AGA++Vsll+lS  +s+GLF++AI+qSG+als+wa++++p   ++++
    KIAA0951   115 GSGAGASCVSLLTLS-HYSEGLFQKAIIQSGTALSSWAVNYQP--AKYTR 161  

                   rlAkllGCpgedseelveCLRkksaeelldaqwklllleefgffplfpFg
                    lA ++GC++ d +++veCL++k+ +el+ ++    ++++   f      
    KIAA0951   162 ILADKVGCNMLDTTDMVECLKNKNYKELIQQTI--TPATYHIAFG----- 204  

                   PVvdGdtpdaflpkdPeellkegnfnkvPlliGvtsdEGllflayvl.dp
                   PV+dGd    ++p+dP++l+++g+f ++++++Gv++ EGl f+  + +++
    KIAA0951   205 PVIDGD----VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVdNE 250  

                   .lsadllseidnedlflellpellpgase.steklreeiadaikeeYtdd
                   + +       d+++   +++ ++l+g++e++     + ++++ik++Ytd+
    KIAA0951   251 dGV----TPNDFDF-SVSNFVDNLYGYPEgK-----DTLRETIKFMYTDW 290  

                   dd.nseesrrdalldllsDylFvcPilrlalaraakagspvYlYrFdyrs
                   +d+ ++e+rr+ l+ l++D+++v+P +++ ++ +a++gsp+Y+Y F +++
    KIAA0951   291 ADkENPETRRKTLVALFTDHQWVAP-AVATADLHAQYGSPTYFYAFYHHC 339  

                   sdsfnqyrinllwppwrgvsHgdelsYvFGnpls.k.ly....sseeeem
                             +++p w    Hgde++YvFG p++++++  + ++s+ ++m
    KIAA0951   340 Q--------SEMKPSWADSAHGDEVPYVFGIPMIgPtELfscnFSKNDVM 381  

                   lssrrmmrywtnFAktGnPN.............ngessglvkWppytkee
                   ls +++m+ywtnFAktG+PN++ +++++  +++++  +++v W +y++++
    KIAA0951   382 LS-AVVMTYWTNFAKTGDPNqpvpqdtkfihtkPNR-FEEVAWSKYNPKD 429  

                   qkyylpitllnitqk.lreedPrkvkcafw<-*
                   q  yl+i+l++++++++r+++     +afw   
    KIAA0951   430 Q-LYLHIGLKPRVRDhYRATK-----VAFW    453  

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