hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-15100651/chunk_1/iprscan-20080502-15100651.nocrc
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Query sequence: KIAA0861
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF00621.11.fs RhoGEF domain                                   62.9    2.3e-18   1
PF00621.11.ls RhoGEF domain                                   60.3    5.8e-15   1
PF00169.19.fs PH domain                                       29.5    1.6e-08   1
PF00169.19.ls PH domain                                       31.5    2.8e-06   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF00621.11.fs   1/1     491   647 ..     1   187 [.    62.9  2.3e-18
PF00621.11.ls   1/1     491   689 ..     1   207 []    60.3  5.8e-15
PF00169.19.fs   1/1     709   822 ..     1    92 []    29.5  1.6e-08
PF00169.19.ls   1/1     709   822 ..     1    92 []    31.5  2.8e-06

Alignments of top-scoring domains:
PF00621.11.fs: domain 1 of 1, from 491 to 647: score 62.9, E = 2.3e-18
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaissk...plLtpddie
                      +++ lleTE+ Y+++   ++++y  p++   i  k+  p++ ++ ++
    KIAA0861   491    IIRDLLETEEIYIKEIKSIIDGYITPMDF--IWLKhliPDVLQNNKD 535  

                   tiFsNiediyefh.reFLkssLearisssnfedlDekkiepsaqrlGdlF
                    +F+Ni ++yefh+r+FLk +Le++++               ++ l+ +F
    KIAA0861   536 FLFGNIRELYEFHnRTFLK-ELEKCAEN--------------PELLAHCF 570  

                   lelkaeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassnt
                   l++k++  q+Y +Y +n p+A  ++     ++  ++F +   ++  +   
    KIAA0861   571 LKRKEDL-QIYFKYHKNLPRARAIWQE---CQDCAYFGVCQRQLDHN--- 613  

                   gAkddavkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedsse<-*
                           l L ++L  P qR+ +Y+ LLk LL++ ++  +++e   
    KIAA0861   614 --------LPLFKYLKGPSQRLIKYQMLLKGLLDFESP--EDME    647  

PF00621.11.ls: domain 1 of 1, from 491 to 689: score 60.3, E = 5.8e-15
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaissk...plLtpddie
                      +++ lleTE+ Y+++   ++++y  p++   i  k+  p++ ++ ++
    KIAA0861   491    IIRDLLETEEIYIKEIKSIIDGYITPMDF--IWLKhliPDVLQNNKD 535  

                   tiFsNiediyefh.reFLkssLearisssnfedlDekkiepsaqrlGdlF
                    +F+Ni ++yefh+r+FLk +Le++++               ++ l+ +F
    KIAA0861   536 FLFGNIRELYEFHnRTFLK-ELEKCAEN--------------PELLAHCF 570  

                   lelkaeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassnt
                   l++k++  q+Y +Y +n p+A  ++     ++  ++F +   ++  +   
    KIAA0861   571 LKRKEDL-QIYFKYHKNLPRARAIWQE---CQDCAYFGVCQRQLDHN--- 613  

                   gAkddavkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedsse......
                           l L ++L  P qR+ +Y+ LLk LL++ ++  +++e ++++ 
    KIAA0861   614 --------LPLFKYLKGPSQRLIKYQMLLKGLLDFESP--EDMEidpgel 653  

                   ................sedLkkaldalqdlaksiNe<-*
                   +++ ++++++++++  s +L++al+ ++dl+ks      
    KIAA0861   654 ggsakdgpkrtkdsafSTELQQALAVIEDLIKSCEL    689  

PF00169.19.fs: domain 1 of 1, from 709 to 822: score 29.5, E = 1.6e-08
                   *->vikeGwLlkkg...........gkkswkkRyfvLfddvLlyykdkk.
                      +  +G +++++ ++++ + ++  + ++ +R + Lf++ ++++k + +
    KIAA0861   709    LLLHGPFSVWTihkdrykmkdlIRFKPSQRQIYLFERGIVFCKIRMe 755  

                   .........kkpkgsipLsgiqvtkvpdnkrkncFeirt.dr.etlllqa
                   +++++ +++++ k+ + L +++++ + ++  +  Fei ++++ e+++lqa
    KIAA0861   756 pgdqglsphYSFKKAMKLMTLSIRQLGRG-SHRKFEIASrNGlEKYILQA 804  

                   eseeerkeWvkaiqsair<-*
                   +s+e r  W + i++++    
    KIAA0861   805 ASKEIRDCWFSEISKLLM    822  

PF00169.19.ls: domain 1 of 1, from 709 to 822: score 31.5, E = 2.8e-06
                   *->vikeGwLlkkg...........gkkswkkRyfvLfddvLlyykdkk.
                      +  +G +++++ ++++ + ++  + ++ +R + Lf++ ++++k + +
    KIAA0861   709    LLLHGPFSVWTihkdrykmkdlIRFKPSQRQIYLFERGIVFCKIRMe 755  

                   .........kkpkgsipLsgiqvtkvpdnkrkncFeirt.dr.etlllqa
                   +++++ +++++ k+ + L +++++ + ++  +  Fei ++++ e+++lqa
    KIAA0861   756 pgdqglsphYSFKKAMKLMTLSIRQLGRG-SHRKFEIASrNGlEKYILQA 804  

                   eseeerkeWvkaiqsair<-*
                   +s+e r  W + i++++    
    KIAA0861   805 ASKEIRDCWFSEISKLLM    822  

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