hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-14294377/chunk_1/iprscan-20080502-14294377.nocrc
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Query sequence: KIAA0837
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
PF00501.18.ls AMP-binding enzyme                          348.7   8.9e-102   1
PF00501.18.fs AMP-binding enzyme                          348.6   9.5e-102   2

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
PF00501.18.fs   1/2     170   438 ..     1   216 [.   148.9  1.2e-41
PF00501.18.ls   1/1     170   636 ..     1   377 []   348.7 8.9e-102
PF00501.18.fs   2/2     476   636 ..   211   377 .]   199.7  6.4e-57

Alignments of top-scoring domains:
PF00501.18.fs: domain 1 of 2, from 170 to 438: score 148.9, E = 1.2e-41
                   *->TYrELderanrlAaaLr..alGvgpGdrVaillpnspelvvailAvl
                      +Y+E+ +ra+ l+++L++++  +  ++ +++++ n+pe++++ lA+ 
    KIAA0837   170    SYQEVADRAEFLGSGLLqhNCKACTDQFIGVFAQNRPEWIIVELACY 216  

                   kaGaayvPldpsypaerlayiledsgakvlltddalla.l..........
                      +++vPl+ ++++ +++yi++ ++++ +++d+  +a l  + ++ +++
    KIAA0837   217 TYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAvLllehverket 266  

                   ......................................s.e.p.ppvdpd
                   ++ +     ++ +++ ++ + + +++ ++  ++++ + ++ + ++p++pd
    KIAA0837   267 pglkliilmdpfeealkergqkcgvviksmqavedcgqEnHqApVPPQPD 316  

                   dlAyiiYTSGTTGkPKGVmltHrnlvnlvaala.rf.l.pdd..aervll
                   dl  +++TSGTTG+PKG+mltH+n+v+ + ++ ++ +    ++++++ ++
    KIAA0837   317 DLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLkVTeKvIFPrqDDVLIS 366  

                   llppllhfdgsvweifgpLlaGatlvlvpkfdryrdpealldliekykvT
                   +lp  l++++      +  ++G+++ ++    +    ++l d++++  +T
    KIAA0837   367 FLP--LAHMFERVIQSVVYCHGGRVGFFQ--GD---IRLLSDDMKALCPT 409  

                   vlflvPtllrlllkape.edlssLrlvls<-*
                   ++  vP+ll+++++ + + +   L++ l+   
    KIAA0837   410 IFPVVPRLLNRMYDKIFsQANTPLKRWLL    438  

PF00501.18.ls: domain 1 of 1, from 170 to 636: score 348.7, E = 8.9e-102
                   *->TYrELderanrlAaaLr..alGvgpGdrVaillpnspelvvailAvl
                      +Y+E+ +ra+ l+++L++++  +  ++ +++++ n+pe++++ lA+ 
    KIAA0837   170    SYQEVADRAEFLGSGLLqhNCKACTDQFIGVFAQNRPEWIIVELACY 216  

                   kaGaayvPldpsypaerlayiledsgakvlltddalla.l..........
                      +++vPl+ ++++ +++yi++ ++++ +++d+  +a l  + ++ +++
    KIAA0837   217 TYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAvLllehverket 266  

                   ......................................s.e.p.ppvdpd
                   ++ +     ++ +++ ++ + + +++ ++  ++++ + ++ + ++p++pd
    KIAA0837   267 pglkliilmdpfeealkergqkcgvviksmqavedcgqEnHqApVPPQPD 316  

                   dlAyiiYTSGTTGkPKGVmltHrnlvnlvaala.rf.l.pdd..aervll
                   dl  +++TSGTTG+PKG+mltH+n+v+ + ++ ++ +    ++++++ ++
    KIAA0837   317 DLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLkVTeKvIFPrqDDVLIS 366  

                   llppllhfdgsvweifgpLlaGatlvlvpkfdryrdpealldliekykvT
                   +lp  l++++      +  ++G+++ ++    +    ++l d++++  +T
    KIAA0837   367 FLP--LAHMFERVIQSVVYCHGGRVGFFQ--GD---IRLLSDDMKALCPT 409  

                   vlflvPtllrlllkape.................................
                   ++  vP+ll+++++ + ++ +++ ++   +   ++++ + +++  ++++ 
    KIAA0837   410 IFPVVPRLLNRMYDKIFsqantplkrwllefaakrkqaevrsgiirndsi 459  

                   ...........edlssLrlvlsgGealppelarrlrerfgsggvrlvngY
                    ++   ++ +      +r +++g+++ +p+++  lr+++g   +++++gY
    KIAA0837   460 wdelffnkiqaSLGGCVRMIVTGAAPASPTVLGFLRAALG---CQVYEGY 506  

                   GpTEttvvatanppg.p.pgsiGrPlpgvevyvlDeeg.qpvppGevGEL
                   G+TE+t ++t++ pg+ ++g++G Plp+  ++++D e  ++ +   +GE+
    KIAA0837   507 GQTECTAGCTFTTPGdWtSGHVGAPLPCNHIKLVDVEElNYWACKGEGEI 556  

                   yirGwpgvarGYlnrPelTaerFvadgwgpGeRmYrTGDlgrwdpDGyle
                   ++rG p+v++GYl++P++T+e+ ++dgw      ++TGD+g+w+p G+l 
    KIAA0837   557 CVRG-PNVFKGYLKDPDRTKEALDSDGW------LHTGDIGKWLPAGTLK 599  

                   ilGRkDdqvKir.GerIepgEiEavLlahPgVaeAaV<-*
                   i++Rk++++K+++Ge+++p+ iE+++ +   Va++ V   
    KIAA0837   600 IIDRKKHIFKLAqGEYVAPEKIENIYIRSQPVAQIYV    636  

PF00501.18.fs: domain 2 of 2, from 476 to 636: score 199.7, E = 6.4e-57
                   *->LrlvlsgGealppelarrlrerfgsggvrlvngYGpTEttvvatanp
                      +r +++g+++ +p+++  lr+++g   +++++gYG+TE+t ++t++ 
    KIAA0837   476    VRMIVTGAAPASPTVLGFLRAALG---CQVYEGYGQTECTAGCTFTT 519  

                   pg.p.pgsiGrPlpgvevyvlDeeg.qpvppGevGELyirGwpgvarGYl
                   pg+ ++g++G Plp+  ++++D e  ++ +   +GE+++rG p+v++GYl
    KIAA0837   520 PGdWtSGHVGAPLPCNHIKLVDVEElNYWACKGEGEICVRG-PNVFKGYL 568  

                   nrPelTaerFvadgwgpGeRmYrTGDlgrwdpDGyleilGRkDdqvKir.
                   ++P++T+e+ ++dgw      ++TGD+g+w+p G+l i++Rk++++K+++
    KIAA0837   569 KDPDRTKEALDSDGW------LHTGDIGKWLPAGTLKIIDRKKHIFKLAq 612  

                   GerIepgEiEavLlahPgVaeAaV<-*
                   Ge+++p+ iE+++ +   Va++ V   
    KIAA0837   613 GEYVAPEKIENIYIRSQPVAQIYV    636  

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