hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-10140962/chunk_1/iprscan-20080502-10140962.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0688 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF05986.4.ls ADAM-TS Spacer 1 190.6 3.6e-54 1 PF05986.4.fs ADAM-TS Spacer 1 188.6 1.4e-53 1 PF01421.9.ls Reprolysin (M12B) family zinc metallo -4.7 1.3e-12 1 PF00090.9.fs Thrombospondin type 1 domain 37.2 1.5e-10 1 PF00090.9.ls Thrombospondin type 1 domain 39.1 1.4e-08 1 PF01421.9.fs Reprolysin (M12B) family zinc metallo 32.0 2.3e-08 2 PF01562.9.fs Reprolysin family propeptide 27.5 4.8e-07 1 PF01562.9.ls Reprolysin family propeptide 17.8 6.2e-07 1 PF08516.2.fs ADAM cysteine-rich 19.0 8.1e-05 2 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF01562.9.fs 1/1 48 154 .. 1 126 [. 27.5 4.8e-07 PF01562.9.ls 1/1 48 194 .. 1 165 [] 17.8 6.2e-07 PF01421.9.ls 1/1 230 440 .. 1 203 [] -4.7 1.3e-12 PF01421.9.fs 1/2 295 389 .. 65 156 .. 24.8 2.1e-06 PF00090.9.ls 1/1 536 586 .. 1 55 [] 39.1 1.4e-08 PF00090.9.fs 1/1 536 586 .. 1 55 [] 37.2 1.5e-10 PF05986.4.fs 1/1 698 815 .. 1 128 [] 188.6 1.4e-53 PF05986.4.ls 1/1 698 815 .. 1 128 [] 190.6 3.6e-54 Alignments of top-scoring domains: PF01562.9.fs: domain 1 of 1, from 48 to 154: score 27.5, E = 4.8e-07 *->lLlllllpglaglgaalgtpweyssyEvviPekl...tsegkrrvkq +Llllll+ l+++ a l++p + +E+v Pekl+++ +g+++ KIAA0688 48 WLLLLLLASLLPS-ARLASP-LPREEEIVFPEKLngsVLPGSGT--- 89 dldirlkslkeekyeeelsYvlrieGkpyiLhLeknrgllapdftvttYd + +l +l+++G++++L Le+ +g ++++tv++ + KIAA0688 90 --------------PARLLCRLQAFGETLLLELEQDSGVQVEGLTVQYLG 125 edGtl..vteepliqdhCyYqGyVeGypnSaVsl<-* ++ +l + e+ ++ G+++G+p+S++sl KIAA0688 126 QAPELlgGAEPGTYLT-----GTINGDPESVASL 154 PF01562.9.ls: domain 1 of 1, from 48 to 194: score 17.8, E = 6.2e-07 *->lLlllllpglaglgaalgtpweyssyEvviPekl...tsegkrrvkq +Llllll+ l+++ a l++p + +E+v Pekl+++ +g+++ KIAA0688 48 WLLLLLLASLLPS-ARLASP-LPREEEIVFPEKLngsVLPGSGT--- 89 dldirlkslkeekyeeelsYvlrieGkpyiLhLeknrgllapdftvttYd + +l +l+++G++++L Le+ +g ++++tv++ + KIAA0688 90 --------------PARLLCRLQAFGETLLLELEQDSGVQVEGLTVQYLG 125 edGtl..vteepliqdhCyYqGyVeGypnSaVslSTCsGGLRGllqlenv ++ +l + e+ ++ G+++G+p+S++sl G L G+lq + KIAA0688 126 QAPELlgGAEPGTYLT-----GTINGDPESVASLHWDGGALLGVLQYRGA 170 sYgIEPlesssgfeAQ.rlPHiiY<-* + ++Ple+ + A ++ Hi+ KIAA0688 171 ELHLQPLEGGTPNSAGgPGAHILR 194 PF01421.9.ls: domain 1 of 1, from 230 to 440: score -4.7, E = 1.3e-12 *->rYiELvIVvDhgmytkygsdlnkirqrVhqivNlvNeiYrpqLNIr. r++E +V+D +m +g + + + + ++ + + ++ Ir+ KIAA0688 230 RFVETLVVADDKMAAFHG---AGLKRYLLTVMAAAAKAFKH-PSIRn 272 .VvLvg...LEIWsdgDkInvqsdandTLhsFgeWRetdLlkrks..... +V+Lv ++ + + s + +v ++a +TL+sF W ++ L + ++++++ KIAA0688 273 pVSLVVtrlVILGSGEEGPQVGPSAAQTLRSFCAW-QRGLNTPEDsdpdh 321 HDnAqLLtgidf....dgntiGaAyvggmCspkrSvGVvqdhspivllvA +D A+L+t d+ + ++ t+G+A vg++C+p rS+++v+d l A KIAA0688 322 FDTAILFTRQDLcgvsTCDTLGMADVGTVCDPARSCAIVEDD---GLQSA 368 vtMAHELGHNLGmtHDdkntdgCtCe....gggsCIMnpvassspskKkF t AHELGH + m HD + +C +++ + + +M+pv + + KIAA0688 369 FTAAHELGHVFNMLHDNSK--PCISLngplSTSRHVMAPVMAHVDPEEPW 416 SnCSkddyqkFltkqkpqCLlNkP<-* S CS +Fl ++ ++CLl+kP KIAA0688 417 SPCSARFITDFLDNGYGHCLLDKP 440 PF01421.9.fs: domain 1 of 2, from 295 to 389: score 24.8, E = 2.1e-06 *->sdandTLhsFgeWRetdLlkrks.....HDnAqLLtgidf....dgn ++a +TL+sF W ++ L + +++++++D A+L+t d+ + ++ KIAA0688 295 PSAAQTLRSFCAW-QRGLNTPEDsdpdhFDTAILFTRQDLcgvsTCD 340 tiGaAyvggmCspkrSvGVvqdhspivllvAvtMAHELGHNLGmtHDdkn t+G+A vg++C+p rS+++v+d l A t AHELGH + m HD + KIAA0688 341 TLGMADVGTVCDPARSCAIVEDD---GLQSAFTAAHELGHVFNMLHDNSK 387 tdgC<-* +C KIAA0688 388 --PC 389 PF00090.9.ls: domain 1 of 1, from 536 to 586: score 39.1, E = 1.4e-08 *->spWseWSpCSVTCGkGirtRqRvcnspaPqkkggepCtgdvqelete +pW++W +CS TCG+G++ R c p+P+ gg+ C+g ++ ++ KIAA0688 536 GPWGPWGDCSRTCGGGVQFSSRDCTRPVPR-NGGKYCEGRRTR--FR 579 aCdmmdkC<-* C + + C KIAA0688 580 SC-NTEDC 586 PF00090.9.fs: domain 1 of 1, from 536 to 586: score 37.2, E = 1.5e-10 *->spWseWSpCSVTCGkGirtRqRvcnspaPqkkggepCtgdvqelete +pW++W +CS TCG+G++ R c p+P+ gg+ C+g ++ ++ KIAA0688 536 GPWGPWGDCSRTCGGGVQFSSRDCTRPVPR-NGGKYCEGRRTR--FR 579 aCdmmdkC<-* C + + C KIAA0688 580 SC-NTEDC 586 PF05986.4.fs: domain 1 of 1, from 698 to 815: score 188.6, E = 1.4e-53 *->ktvkGtFtkaslgaGYndVvtIPaGArhIlIrElkkSgqrnddnyLA +++G+F+k++ +GYn+VvtIPaGA+hIl+r+++++g+r+ yLA KIAA0688 698 SKQSGSFRKFR--YGYNNVVTIPAGATHILVRQQGNPGHRS--IYLA 740 LknsdTGskyiLNGnwtisapgrtfelaGTv.feYsrisddvsntapEsL Lk d Gs y LNG++t++++ +++ l G+v+++Ys+ +++ a E+L KIAA0688 741 LKLPD-GS-YALNGEYTLMPSPTDVVLPGAVsLRYSG-ATA----ASETL 783 tatGPtnepLivqvLfqggapnpgikYeYtiP<-* +++GP+ +pL++qvL+ g+ ++++++Y++++P KIAA0688 784 SGHGPLAQPLTLQVLVAGNPQDTRLRYSFFVP 815 PF05986.4.ls: domain 1 of 1, from 698 to 815: score 190.6, E = 3.6e-54 *->ktvkGtFtkaslgaGYndVvtIPaGArhIlIrElkkSgqrnddnyLA +++G+F+k++ +GYn+VvtIPaGA+hIl+r+++++g+r+ yLA KIAA0688 698 SKQSGSFRKFR--YGYNNVVTIPAGATHILVRQQGNPGHRS--IYLA 740 LknsdTGskyiLNGnwtisapgrtfelaGTv.feYsrisddvsntapEsL Lk d Gs y LNG++t++++ +++ l G+v+++Ys+ +++ a E+L KIAA0688 741 LKLPD-GS-YALNGEYTLMPSPTDVVLPGAVsLRYSG-ATA----ASETL 783 tatGPtnepLivqvLfqggapnpgikYeYtiP<-* +++GP+ +pL++qvL+ g+ ++++++Y++++P KIAA0688 784 SGHGPLAQPLTLQVLVAGNPQDTRLRYSFFVP 815 //