# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/hk02064.fasta.huge -Q ../query/KIAA0665.ptfa ./tmplib.23663 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 KIAA0665, 760 aa
 vs ./tmplib.23663 library

1986745 residues in  2037 sequences
  Expectation_n fit: rho(ln(x))= 14.1727+/-0.0112; mu= -24.5110+/- 0.753
 mean_var=727.1098+/-174.637, 0's: 0 Z-trim: 1  B-trim: 0 in 0/40
 Lambda= 0.047564

FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 38, opt: 26, open/ext: -10/-2, width:  16
The best scores are:                                      opt bits E(2037)
KIAA1821  ( 609 res)   fh12913                     ( 609) 1095 90.2 6.5e-19


>>KIAA1821  ( 609 res)   fh12913                          (609 aa)
 initn: 1305 init1: 619 opt: 1095  Z-score: 431.5  bits: 90.2 E(): 6.5e-19
Smith-Waterman score: 1270;  39.836% identity (67.377% similar) in 610 aa overlap (221-760:3-608)

              200       210       220       230        240         
KIAA06 LSQTHPLPSEPVGSQEDGPRLRAVFDALDGDGDGFVRIEDFIQFATVYG-AEQVKDLTKY
                                     : :::.:.:    ..  .: .:.:. :.::
KIAA18                             GRDPDGFLRVERVAALGLRFGQGEEVEKLVKY
                                           10        20        30  

     250       260       270       280       290       300         
KIAA06 LDPSGLGVISFEDFYQGITAIRNGDPDGQCYGGVASAQDEEPLACPDEFDDFVTYEANEV
       :::. :: :.:.:: .:. :... .   .    : :...   : :  :. : :  ...::
KIAA18 LDPNDLGRINFKDFCRGVFAMKGCE---ELLKDVLSVESAGTLPCAPEIPDCVE-QGSEV
             40        50           60        70        80         

     310       320         330       340               350         
KIAA06 TDSAYMGSESTYSECETFTD--EDTSTLVHPELQPEGDADSA--------GGSAVPSEC-
       :  ..  .:    :   : .  :.. ::. ::   :  .::         :. . :.:  
KIAA18 TGPTFADGELIPREPGFFPEDEEEAMTLAPPEGPQELYTDSPMESTQSLEGSVGSPAEKD
       90       100       110       120       130       140        

        360       370       380         390       400       410    
KIAA06 --LDAMEEPDHGALLLLPGRPHPH--GQSVITVIGGEEHFEDYGEGSEAELSPETLCN--
         : ..  :.  .:.  :.        .:. ..:..::.:::::::.... .: . :   
KIAA18 GGLGGLFLPEDKSLVHTPSMTTSDLSTHSTTSLISNEEQFEDYGEGDDVDCAPSSPCPDD
      150       160       170       180       190       200        

                     420                                           
KIAA06 -------GQLGCS--DPAFLTP--------------------------------------
              ..:: :  . :  ::                                      
KIAA18 ETRTNVYSDLGSSVSSSAGQTPRKMRHVYNSELLDVYCSQCCKKINLLNDLEARLKNLKA
      210       220       230       240       250       260        

          430       440         450       460       470       480  
KIAA06 -SPTKRLSSKKVARYLHQSGALTME--ALEDPSPELMEGPEEDIADKVVFLERRVLELEK
        ::....::   .: : .:. ..    . ::   . ... ..::..:: :::..: :::.
KIAA18 NSPNRKISSTAFGRQLMHSSNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELEN
      270       280       290       300       310       320        

            490       500       510       520       530       540  
KIAA06 DTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKS
       :. ..:. .:.:.::: :::::.. :::..:.::  : . . ::.::..:   :.::::.
KIAA18 DSLTNGDLKSKLKQENTQLVHRVHELEEMVKDQETTAEQALEEEARRHREAYGKLEREKA
      330       340       350       360       370       380        

            550       560       570       580       590       600  
KIAA06 IEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKR
        :.: :..:.:::.:::.:::. .  ::.. :.:.::.:.. :..:. .:::..:..  .
KIAA18 TEVELLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDEMDLYK
      390       400       410       420       430       440        

            610       620       630       640        650       660 
KIAA06 RMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQR-RGRSSSMGLQEYHSR
       :: :.: ..: .::...::::::::::::.:::::. ::. :.  ::::.: :: :...:
KIAA18 RMMDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNAR
      450       460       470       480       490       500        

             670       680       690       700        710       720
KIAA06 ARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAF-SESLAAEISSVS
       ::: :::.::.::::.: .:..::..:::::..::.  ::.::..   ..::::::...:
KIAA18 AREVELEHEVKRLKQENYKLRDQNDDLNGQILSLSLYEAKNLFAAQTKAQSLAAEIDTAS
      510       520       530       540       550       560        

              730       740       750       760 
KIAA06 RDELMEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK 
       :::::::...::::::::..:.:.::.::.. ::::::.: 
KIAA18 RDELMEALKEQEEINFRLRQYMDKIILAILDHNPSILEIKH
      570       580       590       600         




760 residues in 1 query   sequences
1986745 residues in 2037 library sequences
 Scomplib [34.26]
 start: Thu Dec 18 15:11:16 2008 done: Thu Dec 18 15:11:16 2008
 Total Scan time:  0.580 Total Display time:  0.020

Function used was FASTA [version 34.26.5 April 26, 2007]