# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/hj03347s1.fasta.nr -Q ../query/KIAA0638.ptfa /cdna2/lib/nr/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
KIAA0638, 1384 aa
vs /cdna2/lib/nr/nr library
2693465022 residues in 7827732 sequences
statistics sampled from 60000 to 7809871 sequences
Expectation_n fit: rho(ln(x))= 6.8163+/-0.000211; mu= 9.0202+/- 0.012
mean_var=171.4540+/-32.172, 0's: 22 Z-trim: 69 B-trim: 4 in 1/66
Lambda= 0.097949
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 40, opt: 28, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7827732)
gi|74723506|sp|Q86UU1.1|PHLB1_HUMAN RecName: Full= (1377) 9054 1292.9 0
gi|114640639|ref|XP_001162204.1| PREDICTED: plecks (1377) 9023 1288.5 0
gi|119587808|gb|EAW67404.1| pleckstrin homology-li (1387) 8922 1274.2 0
gi|73954683|ref|XP_546499.2| PREDICTED: similar to (1381) 8671 1238.8 0
gi|114640649|ref|XP_001162611.1| PREDICTED: plecks (1366) 8635 1233.7 0
gi|109483403|ref|XP_576401.2| PREDICTED: similar t (1485) 8239 1177.8 0
gi|81892500|sp|Q6PDH0.1|PHLB1_MOUSE RecName: Full= (1371) 8158 1166.3 0
gi|114640647|ref|XP_001162895.1| PREDICTED: plecks (1362) 7634 1092.2 0
gi|114640645|ref|XP_001162477.1| PREDICTED: plecks (1381) 7066 1012.0 0
gi|194673236|ref|XP_613593.4| PREDICTED: pleckstri (1384) 6731 964.6 0
gi|114640643|ref|XP_001162564.1| PREDICTED: plecks (1377) 6101 875.6 0
gi|18676488|dbj|BAB84896.1| FLJ00141 protein [Homo (1326) 6021 864.3 0
gi|119587809|gb|EAW67405.1| pleckstrin homology-li (1019) 5998 860.9 0
gi|68533599|gb|AAH98586.1| PHLDB1 protein [Homo sa ( 995) 5996 860.6 0
gi|119587806|gb|EAW67402.1| pleckstrin homology-li (1319) 5996 860.7 0
gi|114640667|ref|XP_001161945.1| PREDICTED: plecks (1212) 5973 857.4 0
gi|114640663|ref|XP_001161980.1| PREDICTED: plecks (1216) 5973 857.4 0
gi|114640661|ref|XP_001162125.1| PREDICTED: plecks (1257) 5973 857.5 0
gi|114640653|ref|XP_001162786.1| PREDICTED: plecks (1319) 5973 857.5 0
gi|114640651|ref|XP_001162312.1| PREDICTED: plecks (1330) 5973 857.5 0
gi|114640665|ref|XP_001162390.1| PREDICTED: plecks (1142) 5296 761.7 0
gi|114640637|ref|XP_001162821.1| PREDICTED: plecks (1409) 5296 761.9 7e-217
gi|114640669|ref|XP_508796.2| PREDICTED: pleckstri ( 906) 5271 758.1 6e-216
gi|114640671|ref|XP_001162736.1| PREDICTED: plecks (1199) 5166 743.4 2.1e-211
gi|114640659|ref|XP_001162520.1| PREDICTED: plecks (1273) 4998 719.7 3.1e-204
gi|114640675|ref|XP_001162652.1| PREDICTED: plecks (1119) 4618 665.9 4.2e-188
gi|154757572|gb|AAI51768.1| PHLDB1 protein [Bos ta ( 663) 3960 572.7 2.9e-160
gi|119587804|gb|EAW67400.1| pleckstrin homology-li ( 731) 3483 505.3 6e-140
gi|167887652|gb|ACA06042.1| pleckstrin homology-li ( 730) 3479 504.8 8.8e-140
gi|34532004|dbj|BAC86289.1| unnamed protein produc ( 731) 3478 504.6 9.7e-140
gi|114640677|ref|XP_001162352.1| PREDICTED: hypoth ( 731) 3477 504.5 1.1e-139
gi|189441915|gb|AAI67599.1| LOC100170555 protein [ (1367) 2804 409.7 6.9e-111
gi|22760678|dbj|BAC11292.1| unnamed protein produc ( 613) 2668 390.1 2.5e-105
gi|194381364|dbj|BAG58636.1| unnamed protein produ ( 373) 2463 360.9 9.3e-97
gi|38196975|gb|AAH13031.2| PHLDB1 protein [Homo sa ( 691) 2438 357.6 1.6e-95
gi|148693664|gb|EDL25611.1| pleckstrin homology-li (1224) 2380 349.7 7e-93
gi|73954681|ref|XP_860465.1| PREDICTED: similar to ( 431) 2359 346.3 2.7e-92
gi|149041490|gb|EDL95331.1| pleckstrin homology-li (1203) 2361 347.0 4.5e-92
gi|14042238|dbj|BAB55164.1| unnamed protein produc ( 402) 2331 342.3 4.1e-91
gi|26342591|dbj|BAC34952.1| unnamed protein produc ( 402) 2249 330.7 1.2e-87
gi|397579|emb|CAA52297.1| LL5 [Rattus norvegicus] ( 781) 1930 285.9 7.2e-74
gi|84029395|sp|Q63312.2|PHLB1_RAT RecName: Full=Pl ( 831) 1930 285.9 7.5e-74
gi|68534820|gb|AAH99035.1| MGC115596 protein [Xeno ( 743) 1806 268.4 1.3e-68
gi|148693665|gb|EDL25612.1| pleckstrin homology-li (1387) 1765 262.9 1.1e-66
gi|123208196|emb|CAM15156.1| novel protein similar (1365) 1672 249.7 9.9e-63
gi|51491166|emb|CAH18649.1| hypothetical protein [ ( 248) 1630 243.0 1.9e-61
gi|193786673|dbj|BAG51996.1| unnamed protein produ ( 280) 1536 229.7 2.1e-57
gi|194382946|dbj|BAG59029.1| unnamed protein produ ( 299) 1497 224.3 1e-55
gi|189536769|ref|XP_689158.3| PREDICTED: wu:fc31d0 (1160) 1378 208.1 2.8e-50
gi|114588415|ref|XP_001153481.1| PREDICTED: plecks (1207) 1340 202.8 1.2e-48
>>gi|74723506|sp|Q86UU1.1|PHLB1_HUMAN RecName: Full=Plec (1377 aa)
initn: 9054 init1: 9054 opt: 9054 Z-score: 6920.1 bits: 1292.9 E(): 0
Smith-Waterman score: 9054; 100.000% identity (100.000% similar) in 1377 aa overlap (8-1384:1-1377)
10 20 30 40 50 60
KIAA06 ELWSLRTMDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
10 20 30 40 50
70 80 90 100 110 120
KIAA06 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 LALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 LALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLG
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSE
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 RVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 RVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLP
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 TRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 TRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGS
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 FSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 FSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYH
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 RRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 RRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 SRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 SRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEV
660 670 680 690 700 710
730 740 750 760 770 780
KIAA06 LALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 LALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAV
720 730 740 750 760 770
790 800 810 820 830 840
KIAA06 DQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 DQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRS
780 790 800 810 820 830
850 860 870 880 890 900
KIAA06 KAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 KAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR
840 850 860 870 880 890
910 920 930 940 950 960
KIAA06 YHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 YHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAK
900 910 920 930 940 950
970 980 990 1000 1010 1020
KIAA06 ASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 ASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQN
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
KIAA06 GTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 GTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGA
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
KIAA06 APFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 APFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACS
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
KIAA06 PDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 PDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERR
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
KIAA06 LQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 LQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVV
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
KIAA06 LSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 LSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYD
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
KIAA06 HLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|747 HLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYT
1320 1330 1340 1350 1360 1370
KIAA06 QFMN
::::
gi|747 QFMN
>>gi|114640639|ref|XP_001162204.1| PREDICTED: pleckstrin (1377 aa)
initn: 9023 init1: 9023 opt: 9023 Z-score: 6896.4 bits: 1288.5 E(): 0
Smith-Waterman score: 9023; 99.710% identity (100.000% similar) in 1377 aa overlap (8-1384:1-1377)
10 20 30 40 50 60
KIAA06 ELWSLRTMDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
:::::::::::::.:::::::::::::::::::::::::::::::::::::::
gi|114 MDALNRNQIGPGCKTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
10 20 30 40 50
70 80 90 100 110 120
KIAA06 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 LALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLG
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSE
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 RVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLP
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 TRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
gi|114 TRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPRKGS
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 FSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 FSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYH
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 RRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 SRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEV
660 670 680 690 700 710
730 740 750 760 770 780
KIAA06 LALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAV
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LALEEERAQVLGRVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAV
720 730 740 750 760 770
790 800 810 820 830 840
KIAA06 DQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 DQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRS
780 790 800 810 820 830
850 860 870 880 890 900
KIAA06 KAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 KAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR
840 850 860 870 880 890
910 920 930 940 950 960
KIAA06 YHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 YHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAK
900 910 920 930 940 950
970 980 990 1000 1010 1020
KIAA06 ASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQN
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
gi|114 ASRQLQVYRSKMDGEATSPLPQTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQN
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
KIAA06 GTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 GTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGA
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
KIAA06 APFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 APFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACS
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
KIAA06 PDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERR
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
KIAA06 LQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVV
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
KIAA06 LSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYD
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
KIAA06 HLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 HLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYT
1320 1330 1340 1350 1360 1370
KIAA06 QFMN
::::
gi|114 QFMN
>>gi|119587808|gb|EAW67404.1| pleckstrin homology-like d (1387 aa)
initn: 8922 init1: 8922 opt: 8922 Z-score: 6819.2 bits: 1274.2 E(): 0
Smith-Waterman score: 9024; 99.279% identity (99.279% similar) in 1387 aa overlap (8-1384:1-1387)
10 20 30 40 50
KIAA06 ELWSLRTMDALNRNQIGPGCQTQTMVQ----------KGPLDLIETGKGLKVQTDKPHLV
:::::::::::::::::::: :::::::::::::::::::::::
gi|119 MDALNRNQIGPGCQTQTMVQMLVLHPYYLQKGPLDLIETGKGLKVQTDKPHLV
10 20 30 40 50
60 70 80 90 100 110
KIAA06 SLGSGRLSTAITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 SLGSGRLSTAITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNAC
60 70 80 90 100 110
120 130 140 150 160 170
KIAA06 TIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 TIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAES
120 130 140 150 160 170
180 190 200 210 220 230
KIAA06 ESLVNGNHTPQTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ESLVNGNHTPQTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLS
180 190 200 210 220 230
240 250 260 270 280 290
KIAA06 PMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPP
240 250 260 270 280 290
300 310 320 330 340 350
KIAA06 LVPARSSSYHLALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LVPARSSSYHLALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEA
300 310 320 330 340 350
360 370 380 390 400 410
KIAA06 RRATESPRLGGQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 RRATESPRLGGQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPP
360 370 380 390 400 410
420 430 440 450 460 470
KIAA06 SPFREPPGSERVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 SPFREPPGSERVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPS
420 430 440 450 460 470
480 490 500 510 520 530
KIAA06 LSRRALSPLPTRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LSRRALSPLPTRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTL
480 490 500 510 520 530
540 550 560 570 580 590
KIAA06 GESLAPHKGSFSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GESLAPHKGSFSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEIS
540 550 560 570 580 590
600 610 620 630 640 650
KIAA06 DNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAT
600 610 620 630 640 650
660 670 680 690 700 710
KIAA06 AALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHED
660 670 680 690 700 710
720 730 740 750 760 770
KIAA06 APSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 APSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAER
720 730 740 750 760 770
780 790 800 810 820 830
KIAA06 ALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER
780 790 800 810 820 830
840 850 860 870 880 890
KIAA06 ELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKE
840 850 860 870 880 890
900 910 920 930 940 950
KIAA06 KEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASP
900 910 920 930 940 950
960 970 980 990 1000 1010
KIAA06 HSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 HSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSP
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
KIAA06 SPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 SPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEA
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
KIAA06 QCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETS
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
KIAA06 ISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEE
1140 1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
KIAA06 RRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 RRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSG
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
KIAA06 HGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 HGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIY
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
KIAA06 FQAIEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 FQAIEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMD
1320 1330 1340 1350 1360 1370
1380
KIAA06 VIVTGAEGYTQFMN
::::::::::::::
gi|119 VIVTGAEGYTQFMN
1380
>>gi|73954683|ref|XP_546499.2| PREDICTED: similar to ple (1381 aa)
initn: 6582 init1: 4504 opt: 8671 Z-score: 6627.6 bits: 1238.8 E(): 0
Smith-Waterman score: 8671; 95.655% identity (98.479% similar) in 1381 aa overlap (8-1384:1-1381)
10 20 30 40 50 60
KIAA06 ELWSLRTMDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
::::::::.::::.::.::.:::::::::::::::::::::::::::::::::
gi|739 MDALNRNQVGPGCKTQAMVKKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
10 20 30 40 50
70 80 90 100 110 120
KIAA06 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
:::::::::.::::::::::::::::::::::::::.:::::::::::::.:::::.:::
gi|739 ITLLPLEEGKTVIGSAARDISLQGPGLAPEHCYIENVRGTLTLYPCGNACSIDGLPIRQP
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
::::::::.:::::::::::::::::::::::::::::::::::: :::::::::::::
gi|739 TRLTQGCMVCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPGSAESESLVNGNHTP
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 QPATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
::::::::::::::::::::::::::::::::::::::::::::.::.::::::::::::
gi|739 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPAPSMPPLVPARSSSYH
240 250 260 270 280 290
310 320 330 340 350
KIAA06 LALQPPQSRPSGAR-SESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRL
::::::: :::::: ::::::.::::::::::::::::::::::::::::::::::::::
gi|739 LALQPPQPRPSGARPSESPRLGRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRL
300 310 320 330 340 350
360 370 380 390 400 410
KIAA06 GGQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGS
::::::::::::::::::: :::::::::::::::::::::::::::::::::::: :..
gi|739 GGQLPVVAISLSEYPASGARSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFRELPST
360 370 380 390 400 410
420 430 440 450 460 470
KIAA06 ERVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPL
:::::::::::::::::::: ..::::::::::::::::::::::::::::::::::::.
gi|739 ERVLTTSPSRQLVGRTFSDGSVARTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPM
420 430 440 450 460 470
480 490 500 510 520 530
KIAA06 PTRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKG
::::::::::.::::::::::::::::::::::::::::::::::::::::::::::.::
gi|739 PTRTTPDPKLTREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPRKG
480 490 500 510 520 530
540 550 560 570 580 590
KIAA06 SFSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEY
:::::::::::::::::::: ::: .::::::::::::::::::::::::::::::::::
gi|739 SFSGRLSPAYSLGSLTGASPRQSPRAQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEY
540 550 560 570 580 590
600 610 620 630 640 650
KIAA06 HRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRR
::::::::: :::::::::::::::::::::::::::: :::::::::::.:::::::::
gi|739 HRRQRQERLWEQEMERLERQRLETILNLCAEYSRADGGLEAGELPSIGEAAAALALAGRR
600 610 620 630 640 650
660 670 680 690 700 710
KIAA06 PSRGLAGA---SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKL
:::::.:: ::::.:::: :: :::: .::::::::::::::::::::::::::::::
gi|739 PSRGLSGAPGASGRSTEEPGGATPRLWECVERSDEENLKEECSSTESTQQEHEDAPSTKL
660 670 680 690 700 710
720 730 740 750 760 770
KIAA06 QGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKE
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
gi|739 QGEVLALEEERAQVLGRVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKE
720 730 740 750 760 770
780 790 800 810 820 830
KIAA06 QKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQG
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
gi|739 QKAVDQLQEKLVTLETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQG
780 790 800 810 820 830
840 850 860 870 880 890
KIAA06 LLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTV
::::.:::::::.:::::::.:::::::::::::::::::::::::::::::::::.::.
gi|739 LLRSQAELLRSITKRKERLAVLDSQAGQIRAQAVQESERLARDKNASLQLLQKEKERLTM
840 850 860 870 880 890
900 910 920 930 940 950
KIAA06 LERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPP
:: ::::::::::::::::::::::.::::::::::::::::::::::::::::.:::::
gi|739 LEGRYHSLTGGRPFPKTTSTLKEMEELLLPAVDLEQWYQELMAGLGTGPAAASPRSSPPP
900 910 920 930 940 950
960 970 980 990 1000 1010
KIAA06 LPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 LPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSAL
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
KIAA06 LTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDA
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 LAQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDA
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
KIAA06 LHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGN
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 LHGAAPFPPGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGN
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
KIAA06 SACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQ
:::::::::::::::.:::::::::::::::::.::::::::::::::::::::::::::
gi|739 SACSPDNMSSASGLDVGKIEEMEKMLKEAHAEKSRLMESREREMELRRQALEEERRRREQ
1140 1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
KIAA06 VERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 VERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTC
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
KIAA06 LHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 LHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEE
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
KIAA06 VYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGA
:::::::::::.::: :..:::::::::::::::::::::::::::::::::::::::::
gi|739 VYYDHLRSAAKRRFFSFSVVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGA
1320 1330 1340 1350 1360 1370
1380
KIAA06 EGYTQFMN
::::::::
gi|739 EGYTQFMN
1380
>>gi|114640649|ref|XP_001162611.1| PREDICTED: pleckstrin (1366 aa)
initn: 8635 init1: 8635 opt: 8635 Z-score: 6600.1 bits: 1233.7 E(): 0
Smith-Waterman score: 8919; 98.911% identity (99.201% similar) in 1377 aa overlap (8-1384:1-1366)
10 20 30 40 50 60
KIAA06 ELWSLRTMDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
:::::::::::::.:::::::::::::::::::::::::::::::::::::::
gi|114 MDALNRNQIGPGCKTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
10 20 30 40 50
70 80 90 100 110 120
KIAA06 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 LALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLG
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSE
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 RVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLP
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 TRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
gi|114 TRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPRKGS
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 FSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 FSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYH
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 RRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 SRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEV
660 670 680 690 700 710
730 740 750 760 770 780
KIAA06 LALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAV
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LALEEERAQVLGRVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAV
720 730 740 750 760 770
790 800 810 820 830 840
KIAA06 DQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 DQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRS
780 790 800 810 820 830
850 860 870 880 890 900
KIAA06 KAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 KAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR
840 850 860 870 880 890
910 920 930 940 950 960
KIAA06 YHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 YHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAK
900 910 920 930 940 950
970 980 990 1000 1010 1020
KIAA06 ASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQN
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
gi|114 ASRQLQVYRSKMDGEATSPLPQTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQN
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
KIAA06 GTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 GTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGA
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
KIAA06 APFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 APFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACS
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
KIAA06 PDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERR
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
KIAA06 LQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVV
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
KIAA06 LSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYD
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
KIAA06 HLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYT
::::::: ::::::::::::::::::::::::::::::::::::::::::
gi|114 HLRSAAK-----------SPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYT
1320 1330 1340 1350 1360
KIAA06 QFMN
::::
gi|114 QFMN
>>gi|109483403|ref|XP_576401.2| PREDICTED: similar to pl (1485 aa)
initn: 6253 init1: 4038 opt: 8239 Z-score: 6297.3 bits: 1177.8 E(): 0
Smith-Waterman score: 8523; 94.092% identity (97.190% similar) in 1388 aa overlap (1-1384:109-1485)
10 20 30
KIAA06 ELWSLRTMDALNRNQIGPGCQTQTMVQKGP
:::: ::: .:::::.::::.::..:::::
gi|109 PGEKQLCPRQPEAAAAHLGEGAGIPPTPHKELWSPRTMATLNRNQLGPGCKTQAVVQKGP
80 90 100 110 120 130
40 50 60 70 80 90
KIAA06 LDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLEEGRTVIGSAARDISLQGPGLAPE
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 LDLIETGQGLKVQTDKPHLVSLGSGRLSTAITLLPLEEGRTVIGSAARDISLQGPGLAPE
140 150 160 170 180 190
100 110 120 130 140 150
KIAA06 HCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 HCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKS
200 210 220 230 240 250
160 170 180 190 200 210
KIAA06 MIPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGPSACASHSSLVSSIEKDLQEIMDS
:::::::::: ::: :::::::::::: : :::.: ::::::::::::::::::::::
gi|109 MIPAGGRAPGSTYSPGSAESESLVNGNHTAQPATRAPPACASHSSLVSSIEKDLQEIMDS
260 270 280 290 300 310
220 230 240 250 260 270
KIAA06 LVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPAS
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
gi|109 LVLEEPGAAGKKPAATSPLSPVANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPAS
320 330 340 350 360 370
280 290 300 310 320
KIAA06 SGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPSGARS-ESPRLSRKGGHERP
::::::::::::::::::::::::::::::::::::::::::.:: :::::.::::::::
gi|109 SGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPSGSRSSESPRLGRKGGHERP
380 390 400 410 420 430
330 340 350 360 370 380
KIAA06 PSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVAISLSEYPASGALSQPTSIPGSP
:::::::::::::::::::::::.:::::::::::::::::::::.::: ::::::::::
gi|109 PSPGLRGLLTDSPAATVLAEARRTTESPRLGGQLPVVAISLSEYPSSGARSQPTSIPGSP
440 450 460 470 480 490
390 400 410 420 430 440
KIAA06 KFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSPSRQLVGRTFSDGLATRTLQPPE
::: :::::::::::::::::::::::::.:::::::::::::::::::: :::::::::
gi|109 KFQSPVPAPRNKIGTLQDRPPSPFREPPGTERVLTTSPSRQLVGRTFSDGSATRTLQPPE
500 510 520 530 540 550
450 460 470 480 490 500
KIAA06 SPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDPKLNREVAESPRPRRWAAHGASP
:::::::::::::::::::::::::::::::.::.:::::.::::::::::::::::.::
gi|109 SPRLGRRGLDSMRELPPLSPSLSRRALSPLPARTAPDPKLSREVAESPRPRRWAAHGTSP
560 570 580 590 600 610
510 520 530 540 550 560
KIAA06 EDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSPAYSLGSLTGASPCQSPCVQRKL
:::::::::::::::::::::::::::.:::::::::::::::::::::: ::: .::::
gi|109 EDFSLTLGARGRRTRSPSPTLGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKL
620 630 640 650 660 670
570 580 590 600 610 620
KIAA06 SSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCA
::::::::. ::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 SSGDLRVPIPRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCA
680 690 700 710 720 730
630 640 650 660 670 680
KIAA06 EYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGA---SGRSSEEPGVATQRLWESM
::::::::::.::::::::::::::::::::::::::: ::::.:: : :.:::::::
gi|109 EYSRADGGPETGELPSIGEATAALALAGRRPSRGLAGAIVVSGRSGEESGGASQRLWESM
740 750 760 770 780 790
690 700 710 720 730 740
KIAA06 ERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQ
::::::::::::::::::::::::::::::::::::.:::::::::.:::::::::::::
gi|109 ERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLAVEEERAQVLGRVEQLKVRVKELEQ
800 810 820 830 840 850
750 760 770 780 790 800
KIAA06 QLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALE
::::.::::::::::::::::::::::::::.:.::::::::::::::::::::::.:::
gi|109 QLQEAAREAEMERALLQGEREAERALLQKEQRAMDQLQEKLVALETGIQKERDKEADALE
860 870 880 890 900 910
810 820 830 840 850 860
KIAA06 TETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIR
:::::::::::::::::::::::::::::::::::::::::..:::::::.:::::::::
gi|109 TETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVSKRKERLAVLDSQAGQIR
920 930 940 950 960 970
870 880 890 900 910 920
KIAA06 AQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLP
::::::::::::.::: ::::::::::::::::::::::::: :::::::::::::::::
gi|109 AQAVQESERLAREKNAVLQLLQKEKEKLTVLERRYHSLTGGRSFPKTTSTLKEMEKLLLP
980 990 1000 1010 1020 1030
930 940 950 960 970 980
KIAA06 AVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRSG
:::::::::::::::::: :::::.:::::::::::::::::::::.:. .:::::::::
gi|109 AVDLEQWYQELMAGLGTGLAAASPRSSPPPLPAKASRQLQVYRSKMNGDMASPLPRTRSG
1040 1050 1060 1070 1080 1090
990 1000 1010 1020 1030 1040
KIAA06 PLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQ
:::::::::::::::::::::::::::::::.::::.:::::::::::::::::::::::
gi|109 PLPSSSGSSSSSSQLSVATLGRSPSPKSALLAQNGTSSLPRNLAATLQDIETKRQLALQQ
1100 1110 1120 1130 1140 1150
1050 1060 1070 1080 1090 1100
KIAA06 KGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGR
::.:::::::::::::::::::::::::::::::: ::::::::: ::::::::::::::
gi|109 KGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAAFPAGPSGFPTLMHHSILHHLPAGR
1160 1170 1180 1190 1200 1210
1110 1120 1130 1140 1150 1160
KIAA06 ERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 ERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAH
1220 1230 1240 1250 1260 1270
1170 1180 1190 1200 1210 1220
KIAA06 AEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQA
:::.:::::::::::::::::::::::::::::::::::::::::::::::.::::::::
gi|109 AEKSRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQA
1280 1290 1300 1310 1320 1330
1230 1240 1250 1260 1270 1280
KIAA06 RPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFV
:::::::: :::::::::::::::::::::::::::::::::::.:::::::::::::::
gi|109 RPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFV
1340 1350 1360 1370 1380 1390
1290 1300 1310 1320 1330 1340
KIAA06 FDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKKRFFRFTMVTESPNPALTF
::::::::::::::::::::::::::::::::::::::::: ::::::::
gi|109 FDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK-----------SPNPALTF
1400 1410 1420 1430 1440
1350 1360 1370 1380
KIAA06 CVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN
::::::::::::::::::::::::::::::::::::::
gi|109 CVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN
1450 1460 1470 1480
>>gi|81892500|sp|Q6PDH0.1|PHLB1_MOUSE RecName: Full=Plec (1371 aa)
initn: 7411 init1: 4009 opt: 8158 Z-score: 6235.8 bits: 1166.3 E(): 0
Smith-Waterman score: 8442; 93.415% identity (97.323% similar) in 1382 aa overlap (8-1384:1-1371)
10 20 30 40 50 60
KIAA06 ELWSLRTMDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
:: :::.:.::::.::..::::::::::::.::::::::::::::::::::::
gi|818 MDPLNRSQLGPGCKTQAVVQKGPLDLIETGQGLKVQTDKPHLVSLGSGRLSTA
10 20 30 40 50
70 80 90 100 110 120
KIAA06 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|818 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
::::::::::::::::::::::::::::::::::: ::::: :.: ::::::::::::
gi|818 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGVRAPGPTYNPGSAESESLVNGNHTA
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
: :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|818 QPATRAPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|818 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
240 250 260 270 280 290
310 320 330 340 350
KIAA06 LALQPPQSRPSGARS-ESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRL
::::::::::::.:: .::::.:::::::::::::::::::::::::::::::.::::::
gi|818 LALQPPQSRPSGSRSSDSPRLGRKGGHERPPSPGLRGLLTDSPAATVLAEARRTTESPRL
300 310 320 330 340 350
360 370 380 390 400 410
KIAA06 GGQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGS
:::::::::::::::.::: :::.::::::::: :::::::::::::::::::::::::.
gi|818 GGQLPVVAISLSEYPSSGARSQPASIPGSPKFQSPVPAPRNKIGTLQDRPPSPFREPPGT
360 370 380 390 400 410
420 430 440 450 460 470
KIAA06 ERVLTTSPSRQLVGRTFSDGLA-TRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSP
:::::.:::::::::::::::: :::::::::::::::::::::::::::::::::::::
gi|818 ERVLTSSPSRQLVGRTFSDGLAATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSP
420 430 440 450 460 470
480 490 500 510 520 530
KIAA06 LPTRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHK
::.::.:::::.::::::::::::::::.:::::::::::::::::::::::::::::.:
gi|818 LPARTAPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPTLGESLAPRK
480 490 500 510 520 530
540 550 560 570 580 590
KIAA06 GSFSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLE
::::::::::::::::::::: ::: .::::::::::::. :::::::::::::::.:::
gi|818 GSFSGRLSPAYSLGSLTGASPRQSPRAQRKLSSGDLRVPIPRERKNSITEISDNEDELLE
540 550 560 570 580 590
600 610 620 630 640 650
KIAA06 YHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGR
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
gi|818 YHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPETGELPSIGEATAALALAGR
600 610 620 630 640 650
660 670 680 690 700 710
KIAA06 RPSRGLAGA---SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTK
::::::::: ::: .:: : :.:::::::::::::::::::::::::::::::::..:
gi|818 RPSRGLAGAIVVSGRCGEESGGASQRLWESMERSDEENLKEECSSTESTQQEHEDAPGAK
660 670 680 690 700 710
720 730 740 750 760 770
KIAA06 LQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQK
::::::.:::::::::.:::::.:::::::::::.:::::::::::::::::::: :::
gi|818 HQGEVLAVEEERAQVLGRVEQLKIRVKELEQQLQEAAREAEMERALLQGEREAERASLQK
720 730 740 750 760 770
780 790 800 810 820 830
KIAA06 EQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQ
::.::::::::::::::::::.:::::.::::::::::::::::::::::::::::::::
gi|818 EQRAVDQLQEKLVALETGIQKDRDKEADALETETKLFEDLEFQQLERESRVEEERELAGQ
780 790 800 810 820 830
840 850 860 870 880 890
KIAA06 GLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLT
::::::::::::..:::::::.:::::::::::::::::::::.:::.:::::::::::.
gi|818 GLLRSKAELLRSVSKRKERLAVLDSQAGQIRAQAVQESERLAREKNAALQLLQKEKEKLN
840 850 860 870 880 890
900 910 920 930 940 950
KIAA06 VLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPP
:::::::::::::::::::::::::::::::::::::::::::.::::: :::::.::::
gi|818 VLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMSGLGTGLAAASPRSSPP
900 910 920 930 940 950
960 970 980 990 1000 1010
KIAA06 PLPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSA
::::::::::::::::::..:.::::::::::::::::::::::::::::::::::::::
gi|818 PLPAKASRQLQVYRSKMDSDAASPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSA
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
KIAA06 LLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWD
::.::::.:::::::::::::::::::::::::.::::::::::::::::::::::::::
gi|818 LLAQNGTSSLPRNLAATLQDIETKRQLALQQKGHQVIEEQRRRLAELKQKAAAEAQCQWD
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
KIAA06 ALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGG
:::::.:: ::::::: :::::::::::::::::::::::::::::::::::::::::::
gi|818 ALHGAGPFSAGPSGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGG
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
KIAA06 NSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRRE
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
gi|818 NSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKSRLMESREREMELRRQALEEERRRRE
1140 1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
KIAA06 QVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDT
::::::::::::::::::::::.:::::::::::::::: ::::::::::::::::::::
gi|818 QVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDT
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
KIAA06 CLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIE
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
gi|818 CLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIE
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
KIAA06 EVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTG
:::::::::::: :::::::::::::::::::::::::::::::::::::
gi|818 EVYYDHLRSAAK-----------SPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTG
1320 1330 1340 1350 1360
1380
KIAA06 AEGYTQFMN
:::::::::
gi|818 AEGYTQFMN
1370
>>gi|114640647|ref|XP_001162895.1| PREDICTED: pleckstrin (1362 aa)
initn: 7591 init1: 5247 opt: 7634 Z-score: 5835.7 bits: 1092.2 E(): 0
Smith-Waterman score: 8400; 92.606% identity (92.887% similar) in 1420 aa overlap (8-1384:1-1362)
10 20 30 40 50 60
KIAA06 ELWSLRTMDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
:::::::::::::.:::::::::::::::::::::::::::::::::::::::
gi|114 MDALNRNQIGPGCKTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
10 20 30 40 50
70 80 90 100 110 120
KIAA06 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 LALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLG
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSE
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 RVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLP
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 TRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
gi|114 TRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPRKGS
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 FSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 FSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYH
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 RRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 SRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEV
660 670 680 690 700 710
730 740 750 760 770 780
KIAA06 LALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAV
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LALEEERAQVLGRVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAV
720 730 740 750 760 770
790 800
KIAA06 DQLQEKLVALETGIQKERDKE---------------------------------------
:::::::::::::::::::::
gi|114 DQLQEKLVALETGIQKERDKERAELAAGRRHLEARQALYAELQTQLDNCPESVREQLQEQ
780 790 800 810 820 830
810 820 830 840 850
KIAA06 ----AEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LRREAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAI
840 850 860 870 880 890
860 870 880 890 900 910
KIAA06 LDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL
900 910 920 930 940 950
920 930 940 950 960 970
KIAA06 KEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEAT
:: :::::::::::
gi|114 KE-----------------------------------------------VYRSKMDGEAT
960
980 990 1000 1010 1020 1030
KIAA06 SPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIE
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SPLPQTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIE
970 980 990 1000 1010 1020
1040 1050 1060 1070 1080 1090
KIAA06 TKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 TKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHS
1030 1040 1050 1060 1070 1080
1100 1110 1120 1130 1140 1150
KIAA06 ILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 ILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEE
1090 1100 1110 1120 1130 1140
1160 1170 1180 1190 1200 1210
KIAA06 MEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 MEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVK
1150 1160 1170 1180 1190 1200
1220 1230 1240 1250 1260 1270
KIAA06 MREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLVKMGGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 MREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLVKMGGKI
1210 1220 1230 1240 1250 1260
1280 1290 1300 1310 1320 1330
KIAA06 KSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKKRFFRFTMVT
::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 KSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK----------
1270 1280 1290 1300 1310
1340 1350 1360 1370 1380
KIAA06 ESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN
::::::::::::::::::::::::::::::::::::::::::::::
gi|114 -SPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN
1320 1330 1340 1350 1360
>>gi|114640645|ref|XP_001162477.1| PREDICTED: pleckstrin (1381 aa)
initn: 7080 init1: 6777 opt: 7066 Z-score: 5401.8 bits: 1012.0 E(): 0
Smith-Waterman score: 8879; 97.845% identity (98.132% similar) in 1392 aa overlap (8-1384:1-1381)
10 20 30 40 50 60
KIAA06 ELWSLRTMDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
:::::::::::::.:::::::::::::::::::::::::::::::::::::::
gi|114 MDALNRNQIGPGCKTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
10 20 30 40 50
70 80 90 100 110 120
KIAA06 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 LALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLG
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSE
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 RVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLP
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 TRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
gi|114 TRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPRKGS
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 FSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 FSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYH
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 RRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 SRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEV
660 670 680 690 700 710
730 740 750 760 770 780
KIAA06 LALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAV
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LALEEERAQVLGRVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAV
720 730 740 750 760 770
790 800 810 820 830 840
KIAA06 DQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 DQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRS
780 790 800 810 820 830
850 860 870 880 890 900
KIAA06 KAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 KAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR
840 850 860 870 880 890
910 920 930 940 950 960
KIAA06 YHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 YHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAK
900 910 920 930 940 950
970 980 990 1000 1010 1020
KIAA06 ASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQN
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
gi|114 ASRQLQVYRSKMDGEATSPLPQTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQN
960 970 980 990 1000 1010
1030 1040 1050 1060
KIAA06 GTGSLPRNLAATLQDIETKRQLALQQK---------------GQQVIEEQRRRLAELKQK
::::::::::::::::::::::::::: ::::::::::::::::::
gi|114 GTGSLPRNLAATLQDIETKRQLALQQKVESLPAEPLPTDDPAGQQVIEEQRRRLAELKQK
1020 1030 1040 1050 1060 1070
1070 1080 1090 1100 1110 1120
KIAA06 AAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 AAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSD
1080 1090 1100 1110 1120 1130
1130 1140 1150 1160 1170 1180
KIAA06 SMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQ
1140 1150 1160 1170 1180 1190
1190 1200 1210 1220 1230 1240
KIAA06 ALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 ALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTH
1200 1210 1220 1230 1240 1250
1250 1260 1270 1280 1290 1300
KIAA06 IESSGHGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 IESSGHGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKL
1260 1270 1280 1290 1300 1310
1310 1320 1330 1340 1350 1360
KIAA06 KGVIYFQAIEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAM
:::::::::::::::::::::: :::::::::::::::::::::::::::
gi|114 KGVIYFQAIEEVYYDHLRSAAK-----------SPNPALTFCVKTHDRLYYMVAPSAEAM
1320 1330 1340 1350 1360
1370 1380
KIAA06 RIWMDVIVTGAEGYTQFMN
:::::::::::::::::::
gi|114 RIWMDVIVTGAEGYTQFMN
1370 1380
>>gi|194673236|ref|XP_613593.4| PREDICTED: pleckstrin ho (1384 aa)
initn: 5036 init1: 3224 opt: 6731 Z-score: 5146.0 bits: 964.6 E(): 0
Smith-Waterman score: 8502; 93.768% identity (96.777% similar) in 1396 aa overlap (8-1384:1-1384)
10 20 30 40 50 60
KIAA06 ELWSLRTMDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
::.:::::.::::.: .:::::::::::::::::::::::::::::::::::
gi|194 MDTLNRNQVGPGCKTPGLVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTA
10 20 30 40 50
70 80 90 100 110 120
KIAA06 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 ITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQP
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP
::::::::::::::::::::::::::::::::::::::::::::: : ::::::::::::
gi|194 TRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPGP-ESESLVNGNHTP
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
: :.::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 QHASRGPSACGSHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLL
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYH
::::::::::::::::::::::::::::::::::::::::::::.::.::::::::::::
gi|194 SPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPAPSLPPLVPARSSSYH
240 250 260 270 280 290
310 320 330 340 350
KIAA06 LALQPPQSRPSGAR-SESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRL
:.:::::::::::: ::::::.:::::::::::::::::::::::::::::::::::::
gi|194 LGLQPPQSRPSGARPSESPRLGRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRP
300 310 320 330 340 350
360 370 380 390 400 410
KIAA06 GGQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGS
::::::::::::::::::: . :::::::::::::::::::::::::::::::::: ::.
gi|194 GGQLPVVAISLSEYPASGARGPPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFRELPGA
360 370 380 390 400 410
420 430 440 450 460 470
KIAA06 ERVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPL
:::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::.
gi|194 ERVLTTSPSRQLVGRTFSDGSATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPV
420 430 440 450 460 470
480 490 500 510 520 530
KIAA06 PTRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKG
:::.:::::.::::::::::::::::::::::::::::::::::::::::::::::.::
gi|194 STRTAPDPKLTREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPRKG
480 490 500 510 520 530
540 550 560 570 580 590
KIAA06 SFSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEY
:::::::::::::::::::: ::: .::::::::::::::::::::::::::::::::::
gi|194 SFSGRLSPAYSLGSLTGASPRQSPRAQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEY
540 550 560 570 580 590
600 610 620 630 640 650
KIAA06 HRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRR
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
gi|194 HRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAAAALALAGRR
600 610 620 630 640 650
660 670 680 690 700 710
KIAA06 PSRGLA---GASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKL
:::::: :: ::.::::: :.::::::.::::::::::::::::::::::::::.:::
gi|194 PSRGLAAGTGAPGRGSEEPGGAAQRLWESVERSDEENLKEECSSTESTQQEHEDAPGTKL
660 670 680 690 700 710
720 730 740 750 760 770
KIAA06 QGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKE
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
gi|194 QGEVLALEEERAQVLGRVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKE
720 730 740 750 760 770
780 790 800 810 820 830
KIAA06 QKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQG
::::::::::::.:::.:::::::::::::::::::::::::::::::::::::::::::
gi|194 QKAVDQLQEKLVTLETSIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQG
780 790 800 810 820 830
840 850 860 870 880 890
KIAA06 LLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTV
:::::::::::::::::::..:::::::::.:::::::.:::::::.:::::::::::..
gi|194 LLRSKAELLRSIAKRKERLVVLDSQAGQIRSQAVQESEHLARDKNAALQLLQKEKEKLAM
840 850 860 870 880 890
900 910 920 930 940 950
KIAA06 LERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
gi|194 LERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPRSSPPP
900 910 920 930 940 950
960 970 980 990 1000 1010
KIAA06 LPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
gi|194 LPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSTL
960 970 980 990 1000 1010
1020 1030 1040 1050 1060
KIAA06 LTQNGTGSLPRNLAATLQDIETKRQLALQQK---------------GQQVIEEQRRRLAE
:.::::.:::::::::::::::::::::::: ::::::::::::::
gi|194 LAQNGTSSLPRNLAATLQDIETKRQLALQQKVESLPAEPLPTDDPAGQQVIEEQRRRLAE
1020 1030 1040 1050 1060 1070
1070 1080 1090 1100 1110 1120
KIAA06 LKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSL
::::::::::::::::::.::::.::.::::::::::::::::.::::::::::::::::
gi|194 LKQKAAAEAQCQWDALHGVAPFPTGPAGFPPLMHHSILHHLPASRERGEEGEHAYDTLSL
1080 1090 1100 1110 1120 1130
1130 1140 1150 1160 1170 1180
KIAA06 ESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREME
::::::::::::::::.:::::::::::::::::::::::::::::::.:::::::::::
gi|194 ESSDSMETSISTGGNSVCSPDNMSSASGLDMGKIEEMEKMLKEAHAEKSRLMESREREME
1140 1150 1160 1170 1180 1190
1190 1200 1210 1220 1230 1240
KIAA06 LRRQALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LRRQALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFD
1200 1210 1220 1230 1240 1250
1250 1260 1270 1280 1290 1300
KIAA06 LKTHIESSGHGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LKTHIESSGHGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKH
1260 1270 1280 1290 1300 1310
1310 1320 1330 1340 1350 1360
KIAA06 ETKLKGVIYFQAIEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPS
:::::::::::::::::::::::::: :::::::::::::::::::::::
gi|194 ETKLKGVIYFQAIEEVYYDHLRSAAK-----------SPNPALTFCVKTHDRLYYMVAPS
1320 1330 1340 1350 1360
1370 1380
KIAA06 AEAMRIWMDVIVTGAEGYTQFMN
:::::::::::::::::::::::
gi|194 AEAMRIWMDVIVTGAEGYTQFMN
1370 1380
1384 residues in 1 query sequences
2693465022 residues in 7827732 library sequences
Tcomplib [34.26] (8 proc)
start: Thu Mar 5 11:35:19 2009 done: Thu Mar 5 11:39:34 2009
Total Scan time: 1998.070 Total Display time: 1.530
Function used was FASTA [version 34.26.5 April 26, 2007]