# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/hg02198b.fasta.nr -Q ../query/KIAA0604.ptfa /cdna2/lib/nr/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
KIAA0604, 773 aa
vs /cdna2/lib/nr/nr library
2693465022 residues in 7827732 sequences
statistics sampled from 60000 to 7825805 sequences
Expectation_n fit: rho(ln(x))= 5.1385+/-0.000183; mu= 13.5746+/- 0.010
mean_var=71.4035+/-13.962, 0's: 40 Z-trim: 53 B-trim: 31 in 1/64
Lambda= 0.151780
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 38, opt: 26, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7827732)
gi|11065940|gb|AAG28399.1|AF192531_1 endothelin-co ( 765) 5148 1136.8 0
gi|119598685|gb|EAW78279.1| hCG2022032, isoform CR ( 766) 5132 1133.3 0
gi|114590794|ref|XP_001148106.1| PREDICTED: endoth ( 765) 5110 1128.5 0
gi|109042851|ref|XP_001099330.1| PREDICTED: endoth ( 765) 5057 1116.9 0
gi|109042848|ref|XP_001099014.1| PREDICTED: endoth ( 765) 5037 1112.5 0
gi|194222648|ref|XP_001497697.2| PREDICTED: endoth ( 765) 5017 1108.1 0
gi|154090993|ref|NP_808873.2| endothelin convertin ( 765) 4961 1095.9 0
gi|74003362|ref|XP_859328.1| PREDICTED: similar to ( 765) 4953 1094.1 0
gi|29150246|gb|AAO72363.1|AF489576_1 endothelin-co ( 765) 4922 1087.3 0
gi|154091022|ref|NP_808871.2| endothelin convertin ( 912) 4898 1082.1 0
gi|119598681|gb|EAW78275.1| hCG2022032, isoform CR ( 787) 4888 1079.9 0
gi|16903013|gb|AAL30386.1|AF428263_1 endothelin co ( 787) 4888 1079.9 0
gi|74003360|ref|XP_849610.1| PREDICTED: similar to ( 816) 4888 1079.9 0
gi|215274248|sp|O60344.4|ECE2_HUMAN RecName: Full= ( 883) 4888 1079.9 0
gi|16903015|gb|AAL30387.1|AF428264_1 endothelin co ( 736) 4876 1077.3 0
gi|21780271|gb|AAM77664.1|AF521189_1 endothelin-co ( 811) 4876 1077.3 0
gi|119598680|gb|EAW78274.1| hCG2022032, isoform CR ( 788) 4872 1076.4 0
gi|37183124|gb|AAQ89362.1| ECE2 [Homo sapiens] ( 736) 4871 1076.2 0
gi|148745743|gb|AAI42951.1| Endothelin converting ( 736) 4865 1074.9 0
gi|29150242|gb|AAO72361.1|AF489574_1 endothelin-co ( 816) 4861 1074.0 0
gi|119598684|gb|EAW78278.1| hCG2022032, isoform CR ( 737) 4860 1073.8 0
gi|114590792|ref|XP_001147750.1| PREDICTED: simila ( 883) 4850 1071.6 0
gi|114590798|ref|XP_001148031.1| PREDICTED: endoth ( 736) 4838 1068.9 0
gi|114590796|ref|XP_526410.2| PREDICTED: endotheli ( 811) 4838 1069.0 0
gi|109042854|ref|XP_001098704.1| PREDICTED: endoth ( 787) 4815 1063.9 0
gi|109042860|ref|XP_001099122.1| PREDICTED: endoth ( 736) 4800 1060.6 0
gi|109042857|ref|XP_001099223.1| PREDICTED: endoth ( 811) 4800 1060.6 0
gi|149731168|ref|XP_001497665.1| PREDICTED: endoth ( 736) 4767 1053.4 0
gi|149731166|ref|XP_001497654.1| PREDICTED: endoth ( 811) 4767 1053.4 0
gi|187952301|gb|AAI38053.1| Endothelin converting ( 763) 4766 1053.2 0
gi|15081461|gb|AAK83919.1| endothelin converting e ( 763) 4760 1051.9 0
gi|154090981|ref|NP_001002815.2| endothelin-conver ( 765) 4746 1048.8 0
gi|154090985|ref|NP_776471.2| endothelin convertin ( 883) 4729 1045.1 0
gi|29150238|gb|AAO72359.1|AF489572_1 endothelin-co ( 763) 4725 1044.2 0
gi|153945864|ref|NP_808810.1| endothelin convertin ( 910) 4713 1041.6 0
gi|154090955|ref|NP_808872.2| endothelin convertin ( 736) 4711 1041.1 0
gi|47169492|tpe|CAE48383.1| TPA: endothelin-conver ( 763) 4709 1040.7 0
gi|29150240|gb|AAO72360.1|AF489573_1 endothelin-co ( 787) 4692 1037.0 0
gi|2136744|pir||I46078 endothelin converting enzym ( 825) 4692 1037.0 0
gi|160332327|sp|Q10711.2|ECE2_BOVIN RecName: Full= ( 883) 4692 1037.0 0
gi|29150244|gb|AAO72362.1|AF489575_1 endothelin-co ( 736) 4674 1033.0 0
gi|29150234|gb|AAO72357.1|AF489570_1 endothelin-co ( 814) 4672 1032.6 0
gi|153945794|ref|NP_808809.1| endothelin convertin ( 881) 4605 1018.0 0
gi|153945742|ref|NP_808811.1| endothelin convertin ( 734) 4585 1013.5 0
gi|29150232|gb|AAO72356.1|AF489569_1 endothelin-co ( 785) 4564 1009.0 0
gi|160380690|sp|Q80Z60.2|ECE2_MOUSE RecName: Full= ( 881) 4564 1009.0 0
gi|29150236|gb|AAO72358.1|AF489571_1 endothelin-co ( 734) 4544 1004.6 0
gi|194375872|dbj|BAG57280.1| unnamed protein produ ( 713) 4445 982.9 0
gi|126314762|ref|XP_001376715.1| PREDICTED: simila ( 877) 4441 982.1 0
gi|26327749|dbj|BAC27618.1| unnamed protein produc ( 709) 4336 959.0 0
>>gi|11065940|gb|AAG28399.1|AF192531_1 endothelin-conver (765 aa)
initn: 5148 init1: 5148 opt: 5148 Z-score: 6085.8 bits: 1136.8 E(): 0
Smith-Waterman score: 5148; 100.000% identity (100.000% similar) in 765 aa overlap (9-773:1-765)
10 20 30 40 50 60
KIAA06 ITAWPDSTMNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
10 20 30 40 50
70 80 90 100 110 120
KIAA06 LGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 LGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQ
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 KTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 KTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 TSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 TSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLS
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNL
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
660 670 680 690 700 710
730 740 750 760 770
KIAA06 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|110 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
720 730 740 750 760
>>gi|119598685|gb|EAW78279.1| hCG2022032, isoform CRA_g (766 aa)
initn: 3222 init1: 3222 opt: 5132 Z-score: 6066.9 bits: 1133.3 E(): 0
Smith-Waterman score: 5132; 99.739% identity (99.869% similar) in 766 aa overlap (9-773:1-766)
10 20 30 40 50 60
KIAA06 ITAWPDSTMNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
10 20 30 40 50
70 80 90 100 110 120
KIAA06 LGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQ
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 KTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 TSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 TSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLS
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
420 430 440 450 460 470
490 500 510 520 530
KIAA06 ALGQLVWMDEKTRQAAKEK-ADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLN
::::::::::::::::::: .:::::::::::::::::::::::::::::::::::::::
gi|119 ALGQLVWMDEKTRQAAKEKVSDAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLN
480 490 500 510 520 530
540 550 560 570 580 590
KIAA06 LYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKAL
540 550 560 570 580 590
600 610 620 630 640 650
KIAA06 NFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 NFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNG
600 610 620 630 640 650
660 670 680 690 700 710
KIAA06 ERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCS
660 670 680 690 700 710
720 730 740 750 760 770
KIAA06 VRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
720 730 740 750 760
>>gi|114590794|ref|XP_001148106.1| PREDICTED: endothelin (765 aa)
initn: 5110 init1: 5110 opt: 5110 Z-score: 6040.9 bits: 1128.5 E(): 0
Smith-Waterman score: 5110; 99.216% identity (99.739% similar) in 765 aa overlap (9-773:1-765)
10 20 30 40 50 60
KIAA06 ITAWPDSTMNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
10 20 30 40 50
70 80 90 100 110 120
KIAA06 LGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LGSRTQLELVLAGVSLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
gi|114 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAER
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 KTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
gi|114 KTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
:::::::::::::::::::::::::::::::::::::::: ::::::::::::.::::::
gi|114 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKGLTAYLDYMEELGLLLGGRP
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 TSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLS
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
gi|114 TSTREQMQQVLELEIQLANITVPQDQRRDEEKISHKMSISELQALAPSMDWLEFLSFLLS
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNL
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
660 670 680 690 700 710
730 740 750 760 770
KIAA06 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
720 730 740 750 760
>>gi|109042851|ref|XP_001099330.1| PREDICTED: endothelin (765 aa)
initn: 5057 init1: 5057 opt: 5057 Z-score: 5978.1 bits: 1116.9 E(): 0
Smith-Waterman score: 5057; 98.039% identity (99.216% similar) in 765 aa overlap (9-773:1-765)
10 20 30 40 50 60
KIAA06 ITAWPDSTMNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
:::::::::::.::::::::::::::: ::::::::::::::::::::::::
gi|109 MNVALQELGAGNNMVEYKRATLRDEDATETPVEGGASPDAMEVGFQKGTRQL
10 20 30 40 50
70 80 90 100 110 120
KIAA06 LGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|109 LGSRTQLELVLAGVSLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
gi|109 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAER
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 KTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
gi|109 KTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 TSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLS
::::::::::::::.::::::::::::::::..:.: : ::::::::::::::::::
gi|109 TSTREQMQQVLELEVQLANITVPQDQRRDEESLYNKPEIFFSQALAPSMDWLEFLSFLLS
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNL
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
gi|109 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNL
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
660 670 680 690 700 710
730 740 750 760 770
KIAA06 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
720 730 740 750 760
>>gi|109042848|ref|XP_001099014.1| PREDICTED: endothelin (765 aa)
initn: 5037 init1: 5037 opt: 5037 Z-score: 5954.5 bits: 1112.5 E(): 0
Smith-Waterman score: 5037; 97.647% identity (98.431% similar) in 765 aa overlap (9-773:1-765)
10 20 30 40 50 60
KIAA06 ITAWPDSTMNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
:::::::::::.::::::::::::::: ::::::::::::::::::::::::
gi|109 MNVALQELGAGNNMVEYKRATLRDEDATETPVEGGASPDAMEVGFQKGTRQL
10 20 30 40 50
70 80 90 100 110 120
KIAA06 LGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|109 LGSRTQLELVLAGVSLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
gi|109 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAER
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 KTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
gi|109 KTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 TSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLS
::::::::::::::.:::::::::::::::: ::::::::::::::::::
gi|109 TSTREQMQQVLELEVQLANITVPQDQRRDEEXXXXXXXXXXXQALAPSMDWLEFLSFLLS
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNL
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
gi|109 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNL
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
660 670 680 690 700 710
730 740 750 760 770
KIAA06 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
720 730 740 750 760
>>gi|194222648|ref|XP_001497697.2| PREDICTED: endothelin (765 aa)
initn: 5017 init1: 5017 opt: 5017 Z-score: 5930.8 bits: 1108.1 E(): 0
Smith-Waterman score: 5017; 96.471% identity (99.739% similar) in 765 aa overlap (9-773:1-765)
10 20 30 40 50 60
KIAA06 ITAWPDSTMNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
:.:::::::.:.::::::::::::::::::::::::::::.::::.: :: .
gi|194 MSVALQELGGGGNMVEYKRATLRDEDAPETPVEGGASPDAVEVGFRKRTRYF
10 20 30 40 50
70 80 90 100 110 120
KIAA06 LGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
:.:::::::::::.:::::::::::.::::::::::::::::::::::.:::::::::::
gi|194 LSSRTQLELVLAGVSLLLAALLLGCFVALGVQYHRDPSHSTCLTEACIQVAGKILESLDR
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQ
:.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
gi|194 GMSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAER
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 KTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
:::::::::::::::::::::::::::.::::::.:::::::::::::::::::::::::
gi|194 KTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNVTGPWDQDNFMEVLKAVAGTYRATPF
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 FTVYVSADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 TSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLS
.::::::.:::::::::::::::::::::::::::::::.::::::::::::::::::::
gi|194 ASTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMSIAELQALAPSMDWLEFLSFLLS
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
:::::::::::.::::::.::::::::::::::::::::::::::::::::::::::::.
gi|194 LETLYGTKKSCMPRWQTCVSNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFED
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNL
::::::::::::::::::::.::::::::::::::::::::::::::.::::::::::::
gi|194 ALGQLVWMDEKTRQAAKEKAEAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNL
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
gi|194 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYSQYQVNGE
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 KLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
660 670 680 690 700 710
730 740 750 760 770
KIAA06 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
720 730 740 750 760
>>gi|154090993|ref|NP_808873.2| endothelin converting en (765 aa)
initn: 4961 init1: 4961 opt: 4961 Z-score: 5864.5 bits: 1095.9 E(): 0
Smith-Waterman score: 4961; 95.556% identity (99.216% similar) in 765 aa overlap (9-773:1-765)
10 20 30 40 50 60
KIAA06 ITAWPDSTMNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
:.:::::::.:.::::::::::::::::::::::::::::.:.::.: : .:
gi|154 MSVALQELGGGGNMVEYKRATLRDEDAPETPVEGGASPDAVEAGFRKRTSRL
10 20 30 40 50
70 80 90 100 110 120
KIAA06 LGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
:: .:::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|154 LGLHTQLELVLAGVSLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
gi|154 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAER
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 KTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
:::::::::::::::::::::::::::.::::::.:::::::::::::::::::::::::
gi|154 KTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNVTGPWDQDNFMEVLKAVAGTYRATPF
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
::::.::::::::::.::::::::::::::::::::::::::::::::::::::::::.:
gi|154 FTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGQP
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 TSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLS
:::::::.:::::::::::::::::::::::::::::::.::::::::::::::::::::
gi|154 TSTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMSIAELQALAPSMDWLEFLSFLLS
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
::::.::::::::: ::::::::::::::::.::::::::::::::::::.:::::::::
gi|154 PLELGDSEPVVVYGTDYLQQVSELINRTEPSVLNNYLIWNLVQKTTSSLDHRFESAQEKL
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
:::::::::::.:::::::::::::::::::::::::::::::::::::::::::.::::
gi|154 LETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEE
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNL
:::.:::::::::::::::::::::::::::::::::::::::::::.::::::::::::
gi|154 ALGHLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNL
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
:::::::::::::::::::::::::::::::::::::::::::::::::::. :::::::
gi|154 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYTCNHPKALN
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
:::::::::::::::::::::::::::::::::::::::::::::::.::::.:::::::
gi|154 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACIEEQYSQYQVNGE
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 KLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
660 670 680 690 700 710
730 740 750 760 770
KIAA06 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
::::::::::::::::::::::::::::::::::::::::::::: :::::::
gi|154 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNSGQLCEVW
720 730 740 750 760
>>gi|74003362|ref|XP_859328.1| PREDICTED: similar to end (765 aa)
initn: 4953 init1: 4953 opt: 4953 Z-score: 5855.1 bits: 1094.1 E(): 0
Smith-Waterman score: 4953; 95.294% identity (99.477% similar) in 765 aa overlap (9-773:1-765)
10 20 30 40 50 60
KIAA06 ITAWPDSTMNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
:::::::::.:.:::::.:.:::.::::::::::::::::.::::.: ::..
gi|740 MNVALQELGGGGNMVEYERTTLREEDAPETPVEGGASPDAVEVGFRKRTRDF
10 20 30 40 50
70 80 90 100 110 120
KIAA06 LGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
:::.::::::::..:::::::::::::::::::: ::::.::::::::::::::::::::
gi|740 LGSHTQLELVLAAVSLLLAALLLGCLVALGVQYHGDPSHNTCLTEACIRVAGKILESLDR
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQ
:::::::::::::::::.::::::::::::::::::::::::::::::::::::.::::.
gi|740 GVSPCEDFYQFSCGGWIQRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSTSEAER
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 KTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
gi|740 KTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|740 FTVYVSADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 TSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLS
:::::::.:::::::::::::::::::::::::::::.:.::::::::.:::::::::::
gi|740 TSTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMNIAELQALAPSVDWLEFLSFLLS
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
::::.::::::::: :::::::::::.::::.::::::::::::::::::.:::::::::
gi|740 PLELGDSEPVVVYGTDYLQQVSELINHTEPSVLNNYLIWNLVQKTTSSLDHRFESAQEKL
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
:::::::::::.:::::::::::::::::::::::::::::::::::::::::::.::::
gi|740 LETLYGTKKSCMPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRNAFEE
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNL
::::::::::::::::::::::::::::::::::.::::::::::::.::::::::::::
gi|740 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILDPKELDDVYDGYEVSEDSFFQNMLNL
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
gi|740 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYTRNHPKALN
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
gi|740 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYSQYQVNGE
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
gi|740 RLNGRQTLGENIADNGGLKAAYNAYKAWLSKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
660 670 680 690 700 710
730 740 750 760 770
KIAA06 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|740 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
720 730 740 750 760
>>gi|29150246|gb|AAO72363.1|AF489576_1 endothelin-conver (765 aa)
initn: 4922 init1: 4922 opt: 4922 Z-score: 5818.4 bits: 1087.3 E(): 0
Smith-Waterman score: 4922; 94.902% identity (98.824% similar) in 765 aa overlap (9-773:1-765)
10 20 30 40 50 60
KIAA06 ITAWPDSTMNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGFQKGTRQL
: :::::::.:.::::::::::::::::::::::::::::.:.::.: : .:
gi|291 MRVALQELGGGGNMVEYKRATLRDEDAPETPVEGGASPDAVEAGFRKRTSRL
10 20 30 40 50
70 80 90 100 110 120
KIAA06 LGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
:: .:::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|291 LGLHTQLELVLAGVSLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDR
60 70 80 90 100 110
130 140 150 160 170 180
KIAA06 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQ
::::::::::::::::::::::::::::::. :::::::::::::::::::::::::::.
gi|291 GVSPCEDFYQFSCGGWIRRNPLPDGRSRWNNSNSLWDQNQAILKHLLENTTFNSSSEAER
120 130 140 150 160 170
190 200 210 220 230 240
KIAA06 KTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPF
::::::::::::::::::::. :::::.::::::.:::::::::::::::::::::::::
gi|291 KTQRFYLSCLQVERIEELGAHALRDLIDKIGGWNVTGPWDQDNFMEVLKAVAGTYRATPF
180 190 200 210 220 230
250 260 270 280 290 300
KIAA06 FTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRP
::::.::::::::::.::::::::::::::::::::::::::::::::::::::::::.:
gi|291 FTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGQP
240 250 260 270 280 290
310 320 330 340 350 360
KIAA06 TSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLS
:::::::.:::::::::::::::::::::::::::::::.::::::::::::::::::::
gi|291 TSTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMSIAELQALAPSMDWLEFLSFLLS
300 310 320 330 340 350
370 380 390 400 410 420
KIAA06 PLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKL
::::.::::::::: ::::::::::::::::.::::::::::::::::::.:::::::::
gi|291 PLELGDSEPVVVYGTDYLQQVSELINRTEPSVLNNYLIWNLVQKTTSSLDHRFESAQEKL
360 370 380 390 400 410
430 440 450 460 470 480
KIAA06 LETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEE
:::::::::::.:::::::::::::::::::::::::::::::::::::::::::.::::
gi|291 LETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRVAFEE
420 430 440 450 460 470
490 500 510 520 530 540
KIAA06 ALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNL
:::.:::::::::::::::::::::::::::::::::::::::::::.::::::::::::
gi|291 ALGHLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNL
480 490 500 510 520 530
550 560 570 580 590 600
KIAA06 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALN
:::::::::::::::::::::::::::::::::::::::::::::::::::. :::.:::
gi|291 YNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYTCNHPQALN
540 550 560 570 580 590
610 620 630 640 650 660
KIAA06 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGE
:::::::::::::::::::::::::::::::::::::::::::::::.::::.:::::::
gi|291 FGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACIEEQYSQYQVNGE
600 610 620 630 640 650
670 680 690 700 710 720
KIAA06 RLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|291 KLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSV
660 670 680 690 700 710
730 740 750 760 770
KIAA06 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
::::::::::::::::::::::::::::::::::::::::::::: :::::::
gi|291 RTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNSGQLCEVW
720 730 740 750 760
>>gi|154091022|ref|NP_808871.2| endothelin converting en (912 aa)
initn: 4898 init1: 4898 opt: 4898 Z-score: 5788.9 bits: 1082.1 E(): 0
Smith-Waterman score: 4898; 95.623% identity (99.204% similar) in 754 aa overlap (20-773:159-912)
10 20 30 40
KIAA06 ITAWPDSTMNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAM
..:::::::::::::::::::::::::::.
gi|154 EKGTLDALLTGEQDPWTVSSEGVHTVDQVLNEMVEYKRATLRDEDAPETPVEGGASPDAV
130 140 150 160 170 180
50 60 70 80 90 100
KIAA06 EVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIR
:.::.: : .::: .:::::::::.:::::::::::::::::::::::::::::::::::
gi|154 EAGFRKRTSRLLGLHTQLELVLAGVSLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIR
190 200 210 220 230 240
110 120 130 140 150 160
KIAA06 VAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 VAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLEN
250 260 270 280 290 300
170 180 190 200 210 220
KIAA06 TTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLK
::::::::::.:::::::::::::::::::::::::::.::::::.::::::::::::::
gi|154 TTFNSSSEAERKTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNVTGPWDQDNFMEVLK
310 320 330 340 350 360
230 240 250 260 270 280
KIAA06 AVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYM
:::::::::::::::.::::::::::.:::::::::::::::::::::::::::::::::
gi|154 AVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYM
370 380 390 400 410 420
290 300 310 320 330 340
KIAA06 EELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSM
:::::::::.::::::::.:::::::::::::::::::::::::::::::.:::::::::
gi|154 EELGMLLGGQPTSTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMSIAELQALAPSM
430 440 450 460 470 480
350 360 370 380 390 400
KIAA06 DWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSL
:::::::::::::::.::::::::: ::::::::::::::::.:::::::::::::::::
gi|154 DWLEFLSFLLSPLELGDSEPVVVYGTDYLQQVSELINRTEPSVLNNYLIWNLVQKTTSSL
490 500 510 520 530 540
410 420 430 440 450 460
KIAA06 DRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEG
:.::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
gi|154 DHRFESAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEG
550 560 570 580 590 600
470 480 490 500 510 520
KIAA06 MISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEIS
::::::.:::::::.:::::::::::::::::::::::::::::::::::::::::::.:
gi|154 MISEIRAAFEEALGHLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVS
610 620 630 640 650 660
530 540 550 560 570 580
KIAA06 EDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 EDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAP
670 680 690 700 710 720
590 600 610 620 630 640
KIAA06 FYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACME
::. ::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
gi|154 FYTCNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACIE
730 740 750 760 770 780
650 660 670 680 690 700
KIAA06 EQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLF
:::.:::::::.::::::::::::::::::::::::::::::::::::::::::::::::
gi|154 EQYSQYQVNGEKLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLF
790 800 810 820 830 840
710 720 730 740 750 760
KIAA06 FVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
gi|154 FVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNSGQL
850 860 870 880 890 900
770
KIAA06 CEVW
::::
gi|154 CEVW
910
773 residues in 1 query sequences
2693465022 residues in 7827732 library sequences
Tcomplib [34.26] (8 proc)
start: Thu Mar 5 09:18:23 2009 done: Thu Mar 5 09:22:17 2009
Total Scan time: 1616.590 Total Display time: 0.480
Function used was FASTA [version 34.26.5 April 26, 2007]