# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/hj02824s1.fasta.nr -Q ../query/KIAA0593.ptfa /cdna2/lib/nr/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
KIAA0593, 2005 aa
vs /cdna2/lib/nr/nr library
2693465022 residues in 7827732 sequences
statistics sampled from 60000 to 7821649 sequences
Expectation_n fit: rho(ln(x))= 6.2545+/-0.000198; mu= 11.9256+/- 0.011
mean_var=114.4001+/-22.403, 0's: 33 Z-trim: 51 B-trim: 564 in 1/68
Lambda= 0.119912
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 42, opt: 30, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7827732)
gi|166214951|sp|Q9UHV7.2|MED13_HUMAN RecName: Full (2174) 13621 2368.9 0
gi|119571823|gb|EAW51438.1| thyroid hormone recept (2174) 13621 2368.9 0
gi|114669769|ref|XP_001138050.1| PREDICTED: mediat (2188) 13588 2363.2 0
gi|4530437|gb|AAD22032.1| thyroid hormone receptor (2174) 13574 2360.8 0
gi|109114565|ref|XP_001110128.1| PREDICTED: mediat (2174) 13496 2347.3 0
gi|194217212|ref|XP_001500884.2| PREDICTED: mediat (2165) 13147 2286.9 0
gi|194675789|ref|XP_603205.4| PREDICTED: similar t (2332) 13124 2282.9 0
gi|73966750|ref|XP_537704.2| PREDICTED: similar to (2182) 13103 2279.3 0
gi|81910189|sp|Q5SWW4.1|MED13_MOUSE RecName: Full= (2171) 12903 2244.7 0
gi|149053743|gb|EDM05560.1| thyroid hormone recept (2040) 12888 2242.1 0
gi|148683837|gb|EDL15784.1| mCG12704 [Mus musculus (1948) 12556 2184.6 0
gi|126307412|ref|XP_001362355.1| PREDICTED: hypoth (2172) 12472 2170.1 0
gi|149635568|ref|XP_001509907.1| PREDICTED: simila (2170) 12418 2160.8 0
gi|109114567|ref|XP_001110078.1| PREDICTED: mediat (1991) 12206 2124.1 0
gi|118100310|ref|XP_415884.2| PREDICTED: similar t (2225) 12135 2111.8 0
gi|74186901|dbj|BAE20510.1| unnamed protein produc (1241) 8050 1404.9 0
gi|118098868|ref|XP_415317.2| PREDICTED: similar t (2195) 4805 843.8 0
gi|148687845|gb|EDL19792.1| thyroid hormone recept (2050) 4754 834.9 0
gi|149720623|ref|XP_001489783.1| PREDICTED: mediat (2190) 4307 757.6 3e-215
gi|73995266|ref|XP_534693.2| PREDICTED: similar to (2280) 4307 757.6 3.1e-215
gi|119909346|ref|XP_595505.3| PREDICTED: similar t (2209) 4281 753.1 6.8e-214
gi|126324384|ref|XP_001365407.1| PREDICTED: simila (2201) 4159 732.0 1.5e-207
gi|6453436|emb|CAB61363.1| hypothetical protein [H (1908) 4157 731.6 1.7e-207
gi|51476392|emb|CAH18186.1| hypothetical protein [ (2069) 4157 731.6 1.8e-207
gi|119618487|gb|EAW98081.1| thyroid hormone recept (2195) 4157 731.7 1.9e-207
gi|74749769|sp|Q71F56.1|MD13L_HUMAN RecName: Full= (2210) 4157 731.7 1.9e-207
gi|109098865|ref|XP_001112106.1| PREDICTED: simila (2210) 4151 730.6 4e-207
gi|67971682|dbj|BAE02183.1| unnamed protein produc ( 611) 4137 727.7 8.2e-207
gi|83305883|sp|Q6JPI3.2|MD13L_MOUSE RecName: Full= (2207) 3924 691.4 2.6e-195
gi|146134449|ref|NP_766012.3| thyroid hormone rece (2207) 3923 691.2 3e-195
gi|126324386|ref|XP_001365474.1| PREDICTED: simila (2199) 3901 687.4 4.2e-194
gi|149063479|gb|EDM13802.1| thyroid hormone recept (1374) 3890 685.3 1.1e-193
gi|38036201|gb|AAR08419.1| thyroid hormone recepto (2203) 3667 646.9 6.4e-182
gi|10435895|dbj|BAB14697.1| unnamed protein produc (1111) 3280 579.7 5.4e-162
gi|30353895|gb|AAH52320.1| Med13l protein [Mus mus (1125) 3174 561.4 1.8e-156
gi|194043001|ref|XP_001925141.1| PREDICTED: mediat (1841) 2742 486.8 8.3e-134
gi|49257394|gb|AAH72653.1| Med13l protein [Mus mus (1879) 2703 480.1 9e-132
gi|47210173|emb|CAF90589.1| unnamed protein produc (2253) 2410 429.4 1.9e-116
gi|47223584|emb|CAF99193.1| unnamed protein produc (1986) 2271 405.4 3e-109
gi|189528813|ref|XP_001921335.1| PREDICTED: simila (1951) 2185 390.5 8.8e-105
gi|166233815|sp|A2VCZ5.1|MD13L_DANRE RecName: Full (2102) 2185 390.5 9.3e-105
gi|189528775|ref|XP_001918662.1| PREDICTED: hypoth (2102) 2185 390.5 9.3e-105
gi|6808448|emb|CAB70855.1| hypothetical protein [H ( 409) 1977 353.9 1.8e-94
gi|47216840|emb|CAG02731.1| unnamed protein produc (2163) 1819 327.2 1.1e-85
gi|74206709|dbj|BAE41604.1| unnamed protein produc ( 525) 1704 306.8 3.7e-80
gi|74184144|dbj|BAE37076.1| unnamed protein produc ( 362) 1655 298.2 9.9e-78
gi|157016223|gb|EAA11333.5| AGAP006436-PA [Anophel (2679) 1640 296.3 2.7e-76
gi|210117040|gb|EEA64780.1| hypothetical protein B (1251) 1351 246.0 1.7e-61
gi|210117029|gb|EEA64769.1| hypothetical protein B (1245) 1349 245.7 2.2e-61
gi|115745092|ref|XP_001203054.1| PREDICTED: simila (1127) 1214 222.3 2.1e-54
>>gi|166214951|sp|Q9UHV7.2|MED13_HUMAN RecName: Full=Med (2174 aa)
initn: 13621 init1: 13621 opt: 13621 Z-score: 12728.8 bits: 2368.9 E(): 0
Smith-Waterman score: 13621; 100.000% identity (100.000% similar) in 2005 aa overlap (1-2005:170-2174)
10 20 30
KIAA05 GDSNVCTSVEINQHQPVYLLSEEHITLAQQ
::::::::::::::::::::::::::::::
gi|166 GKWFVKPYEKDEKPINKSEHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHITLAQQ
140 150 160 170 180 190
40 50 60 70 80 90
KIAA05 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
200 210 220 230 240 250
100 110 120 130 140 150
KIAA05 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
260 270 280 290 300 310
160 170 180 190 200 210
KIAA05 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
320 330 340 350 360 370
220 230 240 250 260 270
KIAA05 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
380 390 400 410 420 430
280 290 300 310 320 330
KIAA05 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
440 450 460 470 480 490
340 350 360 370 380 390
KIAA05 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
500 510 520 530 540 550
400 410 420 430 440 450
KIAA05 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
560 570 580 590 600 610
460 470 480 490 500 510
KIAA05 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
620 630 640 650 660 670
520 530 540 550 560 570
KIAA05 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
680 690 700 710 720 730
580 590 600 610 620 630
KIAA05 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
740 750 760 770 780 790
640 650 660 670 680 690
KIAA05 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
800 810 820 830 840 850
700 710 720 730 740 750
KIAA05 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
860 870 880 890 900 910
760 770 780 790 800 810
KIAA05 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
920 930 940 950 960 970
820 830 840 850 860 870
KIAA05 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
980 990 1000 1010 1020 1030
880 890 900 910 920 930
KIAA05 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
1040 1050 1060 1070 1080 1090
940 950 960 970 980 990
KIAA05 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
1100 1110 1120 1130 1140 1150
1000 1010 1020 1030 1040 1050
KIAA05 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
1160 1170 1180 1190 1200 1210
1060 1070 1080 1090 1100 1110
KIAA05 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
1220 1230 1240 1250 1260 1270
1120 1130 1140 1150 1160 1170
KIAA05 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
1280 1290 1300 1310 1320 1330
1180 1190 1200 1210 1220 1230
KIAA05 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
1340 1350 1360 1370 1380 1390
1240 1250 1260 1270 1280 1290
KIAA05 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
1400 1410 1420 1430 1440 1450
1300 1310 1320 1330 1340 1350
KIAA05 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
1460 1470 1480 1490 1500 1510
1360 1370 1380 1390 1400 1410
KIAA05 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
1520 1530 1540 1550 1560 1570
1420 1430 1440 1450 1460 1470
KIAA05 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
1580 1590 1600 1610 1620 1630
1480 1490 1500 1510 1520 1530
KIAA05 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
1640 1650 1660 1670 1680 1690
1540 1550 1560 1570 1580 1590
KIAA05 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
1700 1710 1720 1730 1740 1750
1600 1610 1620 1630 1640 1650
KIAA05 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
1760 1770 1780 1790 1800 1810
1660 1670 1680 1690 1700 1710
KIAA05 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
1820 1830 1840 1850 1860 1870
1720 1730 1740 1750 1760 1770
KIAA05 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
1880 1890 1900 1910 1920 1930
1780 1790 1800 1810 1820 1830
KIAA05 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
1940 1950 1960 1970 1980 1990
1840 1850 1860 1870 1880 1890
KIAA05 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
2000 2010 2020 2030 2040 2050
1900 1910 1920 1930 1940 1950
KIAA05 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
2060 2070 2080 2090 2100 2110
1960 1970 1980 1990 2000
KIAA05 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
2120 2130 2140 2150 2160 2170
>>gi|119571823|gb|EAW51438.1| thyroid hormone receptor a (2174 aa)
initn: 13621 init1: 13621 opt: 13621 Z-score: 12728.8 bits: 2368.9 E(): 0
Smith-Waterman score: 13621; 100.000% identity (100.000% similar) in 2005 aa overlap (1-2005:170-2174)
10 20 30
KIAA05 GDSNVCTSVEINQHQPVYLLSEEHITLAQQ
::::::::::::::::::::::::::::::
gi|119 GKWFVKPYEKDEKPINKSEHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHITLAQQ
140 150 160 170 180 190
40 50 60 70 80 90
KIAA05 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
200 210 220 230 240 250
100 110 120 130 140 150
KIAA05 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
260 270 280 290 300 310
160 170 180 190 200 210
KIAA05 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
320 330 340 350 360 370
220 230 240 250 260 270
KIAA05 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
380 390 400 410 420 430
280 290 300 310 320 330
KIAA05 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
440 450 460 470 480 490
340 350 360 370 380 390
KIAA05 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
500 510 520 530 540 550
400 410 420 430 440 450
KIAA05 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
560 570 580 590 600 610
460 470 480 490 500 510
KIAA05 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
620 630 640 650 660 670
520 530 540 550 560 570
KIAA05 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
680 690 700 710 720 730
580 590 600 610 620 630
KIAA05 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
740 750 760 770 780 790
640 650 660 670 680 690
KIAA05 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
800 810 820 830 840 850
700 710 720 730 740 750
KIAA05 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
860 870 880 890 900 910
760 770 780 790 800 810
KIAA05 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
920 930 940 950 960 970
820 830 840 850 860 870
KIAA05 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
980 990 1000 1010 1020 1030
880 890 900 910 920 930
KIAA05 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
1040 1050 1060 1070 1080 1090
940 950 960 970 980 990
KIAA05 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
1100 1110 1120 1130 1140 1150
1000 1010 1020 1030 1040 1050
KIAA05 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
1160 1170 1180 1190 1200 1210
1060 1070 1080 1090 1100 1110
KIAA05 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
1220 1230 1240 1250 1260 1270
1120 1130 1140 1150 1160 1170
KIAA05 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
1280 1290 1300 1310 1320 1330
1180 1190 1200 1210 1220 1230
KIAA05 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
1340 1350 1360 1370 1380 1390
1240 1250 1260 1270 1280 1290
KIAA05 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
1400 1410 1420 1430 1440 1450
1300 1310 1320 1330 1340 1350
KIAA05 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
1460 1470 1480 1490 1500 1510
1360 1370 1380 1390 1400 1410
KIAA05 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
1520 1530 1540 1550 1560 1570
1420 1430 1440 1450 1460 1470
KIAA05 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
1580 1590 1600 1610 1620 1630
1480 1490 1500 1510 1520 1530
KIAA05 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
1640 1650 1660 1670 1680 1690
1540 1550 1560 1570 1580 1590
KIAA05 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
1700 1710 1720 1730 1740 1750
1600 1610 1620 1630 1640 1650
KIAA05 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
1760 1770 1780 1790 1800 1810
1660 1670 1680 1690 1700 1710
KIAA05 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
1820 1830 1840 1850 1860 1870
1720 1730 1740 1750 1760 1770
KIAA05 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
1880 1890 1900 1910 1920 1930
1780 1790 1800 1810 1820 1830
KIAA05 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
1940 1950 1960 1970 1980 1990
1840 1850 1860 1870 1880 1890
KIAA05 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
2000 2010 2020 2030 2040 2050
1900 1910 1920 1930 1940 1950
KIAA05 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
2060 2070 2080 2090 2100 2110
1960 1970 1980 1990 2000
KIAA05 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
2120 2130 2140 2150 2160 2170
>>gi|114669769|ref|XP_001138050.1| PREDICTED: mediator o (2188 aa)
initn: 13588 init1: 13588 opt: 13588 Z-score: 12697.9 bits: 2363.2 E(): 0
Smith-Waterman score: 13588; 99.651% identity (99.900% similar) in 2005 aa overlap (1-2005:184-2188)
10 20 30
KIAA05 GDSNVCTSVEINQHQPVYLLSEEHITLAQQ
::::::::::::::::::::::::::::::
gi|114 GKWFVKPYEKDEKPINKSEHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHITLAQQ
160 170 180 190 200 210
40 50 60 70 80 90
KIAA05 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
220 230 240 250 260 270
100 110 120 130 140 150
KIAA05 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
280 290 300 310 320 330
160 170 180 190 200 210
KIAA05 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
340 350 360 370 380 390
220 230 240 250 260 270
KIAA05 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
400 410 420 430 440 450
280 290 300 310 320 330
KIAA05 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
460 470 480 490 500 510
340 350 360 370 380 390
KIAA05 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
gi|114 SAPDSQVRFSNIRTNDVAKTPQMHGAEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
520 530 540 550 560 570
400 410 420 430 440 450
KIAA05 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
gi|114 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEADIAWKYYK
580 590 600 610 620 630
460 470 480 490 500 510
KIAA05 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
640 650 660 670 680 690
520 530 540 550 560 570
KIAA05 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
700 710 720 730 740 750
580 590 600 610 620 630
KIAA05 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
760 770 780 790 800 810
640 650 660 670 680 690
KIAA05 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
820 830 840 850 860 870
700 710 720 730 740 750
KIAA05 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 MDTAPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
880 890 900 910 920 930
760 770 780 790 800 810
KIAA05 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
gi|114 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGPAYTPQ
940 950 960 970 980 990
820 830 840 850 860 870
KIAA05 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
1000 1010 1020 1030 1040 1050
880 890 900 910 920 930
KIAA05 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
1060 1070 1080 1090 1100 1110
940 950 960 970 980 990
KIAA05 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
1120 1130 1140 1150 1160 1170
1000 1010 1020 1030 1040 1050
KIAA05 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
1180 1190 1200 1210 1220 1230
1060 1070 1080 1090 1100 1110
KIAA05 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
1240 1250 1260 1270 1280 1290
1120 1130 1140 1150 1160 1170
KIAA05 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
1300 1310 1320 1330 1340 1350
1180 1190 1200 1210 1220 1230
KIAA05 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
1360 1370 1380 1390 1400 1410
1240 1250 1260 1270 1280 1290
KIAA05 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RLGQHRPISRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
1420 1430 1440 1450 1460 1470
1300 1310 1320 1330 1340 1350
KIAA05 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
gi|114 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAVSSTMTVTSG
1480 1490 1500 1510 1520 1530
1360 1370 1380 1390 1400 1410
KIAA05 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
1540 1550 1560 1570 1580 1590
1420 1430 1440 1450 1460 1470
KIAA05 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
1600 1610 1620 1630 1640 1650
1480 1490 1500 1510 1520 1530
KIAA05 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
1660 1670 1680 1690 1700 1710
1540 1550 1560 1570 1580 1590
KIAA05 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
1720 1730 1740 1750 1760 1770
1600 1610 1620 1630 1640 1650
KIAA05 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
1780 1790 1800 1810 1820 1830
1660 1670 1680 1690 1700 1710
KIAA05 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
1840 1850 1860 1870 1880 1890
1720 1730 1740 1750 1760 1770
KIAA05 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
1900 1910 1920 1930 1940 1950
1780 1790 1800 1810 1820 1830
KIAA05 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
1960 1970 1980 1990 2000 2010
1840 1850 1860 1870 1880 1890
KIAA05 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
2020 2030 2040 2050 2060 2070
1900 1910 1920 1930 1940 1950
KIAA05 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
2080 2090 2100 2110 2120 2130
1960 1970 1980 1990 2000
KIAA05 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
::::::::::::::::::::::::::::: :::::::::::::::::::::::::
gi|114 PLDSNQTSDVLRFVLEQYNALSWLTCDPAIQDRRSCLPIHFVVLNQLYNFIMNML
2140 2150 2160 2170 2180
>>gi|4530437|gb|AAD22032.1| thyroid hormone receptor-ass (2174 aa)
initn: 13574 init1: 13574 opt: 13574 Z-score: 12684.9 bits: 2360.8 E(): 0
Smith-Waterman score: 13574; 99.701% identity (99.850% similar) in 2005 aa overlap (1-2005:170-2174)
10 20 30
KIAA05 GDSNVCTSVEINQHQPVYLLSEEHITLAQQ
::::::::::::::::::::::::::::::
gi|453 GKWFVKPYEKDEKPINKSEHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHITLAQQ
140 150 160 170 180 190
40 50 60 70 80 90
KIAA05 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
200 210 220 230 240 250
100 110 120 130 140 150
KIAA05 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
260 270 280 290 300 310
160 170 180 190 200 210
KIAA05 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
320 330 340 350 360 370
220 230 240 250 260 270
KIAA05 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
gi|453 WQECNMNRAQNKKKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
380 390 400 410 420 430
280 290 300 310 320 330
KIAA05 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
gi|453 QGQAPSLGQQQQILPKHKTNEKQEKSEEPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
440 450 460 470 480 490
340 350 360 370 380 390
KIAA05 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
500 510 520 530 540 550
400 410 420 430 440 450
KIAA05 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
560 570 580 590 600 610
460 470 480 490 500 510
KIAA05 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
620 630 640 650 660 670
520 530 540 550 560 570
KIAA05 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
680 690 700 710 720 730
580 590 600 610 620 630
KIAA05 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
740 750 760 770 780 790
640 650 660 670 680 690
KIAA05 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 RSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
800 810 820 830 840 850
700 710 720 730 740 750
KIAA05 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
860 870 880 890 900 910
760 770 780 790 800 810
KIAA05 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 LKTLPSQYLPLIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
920 930 940 950 960 970
820 830 840 850 860 870
KIAA05 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 THTSCGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
980 990 1000 1010 1020 1030
880 890 900 910 920 930
KIAA05 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
gi|453 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNSDSCCICVCN
1040 1050 1060 1070 1080 1090
940 950 960 970 980 990
KIAA05 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
1100 1110 1120 1130 1140 1150
1000 1010 1020 1030 1040 1050
KIAA05 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
1160 1170 1180 1190 1200 1210
1060 1070 1080 1090 1100 1110
KIAA05 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
1220 1230 1240 1250 1260 1270
1120 1130 1140 1150 1160 1170
KIAA05 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
1280 1290 1300 1310 1320 1330
1180 1190 1200 1210 1220 1230
KIAA05 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
1340 1350 1360 1370 1380 1390
1240 1250 1260 1270 1280 1290
KIAA05 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
1400 1410 1420 1430 1440 1450
1300 1310 1320 1330 1340 1350
KIAA05 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
1460 1470 1480 1490 1500 1510
1360 1370 1380 1390 1400 1410
KIAA05 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
1520 1530 1540 1550 1560 1570
1420 1430 1440 1450 1460 1470
KIAA05 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
1580 1590 1600 1610 1620 1630
1480 1490 1500 1510 1520 1530
KIAA05 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
1640 1650 1660 1670 1680 1690
1540 1550 1560 1570 1580 1590
KIAA05 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
1700 1710 1720 1730 1740 1750
1600 1610 1620 1630 1640 1650
KIAA05 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
1760 1770 1780 1790 1800 1810
1660 1670 1680 1690 1700 1710
KIAA05 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
1820 1830 1840 1850 1860 1870
1720 1730 1740 1750 1760 1770
KIAA05 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
1880 1890 1900 1910 1920 1930
1780 1790 1800 1810 1820 1830
KIAA05 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
1940 1950 1960 1970 1980 1990
1840 1850 1860 1870 1880 1890
KIAA05 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
2000 2010 2020 2030 2040 2050
1900 1910 1920 1930 1940 1950
KIAA05 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
2060 2070 2080 2090 2100 2110
1960 1970 1980 1990 2000
KIAA05 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
2120 2130 2140 2150 2160 2170
>>gi|109114565|ref|XP_001110128.1| PREDICTED: mediator o (2174 aa)
initn: 13496 init1: 13496 opt: 13496 Z-score: 12612.0 bits: 2347.3 E(): 0
Smith-Waterman score: 13496; 98.853% identity (99.751% similar) in 2005 aa overlap (1-2005:170-2174)
10 20 30
KIAA05 GDSNVCTSVEINQHQPVYLLSEEHITLAQQ
::::::::::::::::::::::::::::::
gi|109 GKWFVKPYEKDEKPINKSEHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHITLAQQ
140 150 160 170 180 190
40 50 60 70 80 90
KIAA05 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
200 210 220 230 240 250
100 110 120 130 140 150
KIAA05 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
260 270 280 290 300 310
160 170 180 190 200 210
KIAA05 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
gi|109 MSSVTLTPPTSPEEVQTVDPQSAQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
320 330 340 350 360 370
220 230 240 250 260 270
KIAA05 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
gi|109 WQECNMNRAQNKRKYSASSGGLCEEVTAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
380 390 400 410 420 430
280 290 300 310 320 330
KIAA05 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
gi|109 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDTDSASQRLVI
440 450 460 470 480 490
340 350 360 370 380 390
KIAA05 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 SAPDSQVRFSSIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
500 510 520 530 540 550
400 410 420 430 440 450
KIAA05 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
560 570 580 590 600 610
460 470 480 490 500 510
KIAA05 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
gi|109 VPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKISDELVQQYQIKN
620 630 640 650 660 670
520 530 540 550 560 570
KIAA05 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 QYLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
680 690 700 710 720 730
580 590 600 610 620 630
KIAA05 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
::::::::::::::::::::.:::::::::::::::::::.:::::::::::::::::::
gi|109 HEEDAMSLFSPSIKQDAPRPASHARPPSTSLIYDSDLAVSFTDLDNLFNSDEDELTPGSK
740 750 760 770 780 790
640 650 660 670 680 690
KIAA05 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 KSANGSDDKTSCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
800 810 820 830 840 850
700 710 720 730 740 750
KIAA05 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
860 870 880 890 900 910
760 770 780 790 800 810
KIAA05 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
::::::::::::::::::::::::::::::::::: .::::::::::::::::: :::::
gi|109 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGSTMPFIKEGDGSNMDQEYGPAYTPQ
920 930 940 950 960 970
820 830 840 850 860 870
KIAA05 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
980 990 1000 1010 1020 1030
880 890 900 910 920 930
KIAA05 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
1040 1050 1060 1070 1080 1090
940 950 960 970 980 990
KIAA05 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
:::::::::::::::::::::::::::::.:::::::.::::::::::::::::::::::
gi|109 MNIKGADVGVYIPDPTQEAQYRCTCGFSAIMNRKFGNSSGLFLEDELDIIGRNTDCGKEA
1100 1110 1120 1130 1140 1150
1000 1010 1020 1030 1040 1050
KIAA05 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 EKRFEALRGTSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
1160 1170 1180 1190 1200 1210
1060 1070 1080 1090 1100 1110
KIAA05 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
1220 1230 1240 1250 1260 1270
1120 1130 1140 1150 1160 1170
KIAA05 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
1280 1290 1300 1310 1320 1330
1180 1190 1200 1210 1220 1230
KIAA05 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
1340 1350 1360 1370 1380 1390
1240 1250 1260 1270 1280 1290
KIAA05 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
gi|109 RLGQHRPVSRLLTDGIMRVGSTASNKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
1400 1410 1420 1430 1440 1450
1300 1310 1320 1330 1340 1350
KIAA05 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
gi|109 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTMTSG
1460 1470 1480 1490 1500 1510
1360 1370 1380 1390 1400 1410
KIAA05 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
1520 1530 1540 1550 1560 1570
1420 1430 1440 1450 1460 1470
KIAA05 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
:::::::::::.:::::::::::::::::::::::::::::::::::::::::.::::::
gi|109 QSGQLGGQQTSTLQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAI
1580 1590 1600 1610 1620 1630
1480 1490 1500 1510 1520 1530
KIAA05 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
gi|109 VVYIIDPFTYENTDESANSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
1640 1650 1660 1670 1680 1690
1540 1550 1560 1570 1580 1590
KIAA05 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
1700 1710 1720 1730 1740 1750
1600 1610 1620 1630 1640 1650
KIAA05 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
1760 1770 1780 1790 1800 1810
1660 1670 1680 1690 1700 1710
KIAA05 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
1820 1830 1840 1850 1860 1870
1720 1730 1740 1750 1760 1770
KIAA05 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
1880 1890 1900 1910 1920 1930
1780 1790 1800 1810 1820 1830
KIAA05 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
1940 1950 1960 1970 1980 1990
1840 1850 1860 1870 1880 1890
KIAA05 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
gi|109 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDVGKGQSTDRLLSTEPHEEVPNIL
2000 2010 2020 2030 2040 2050
1900 1910 1920 1930 1940 1950
KIAA05 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
2060 2070 2080 2090 2100 2110
1960 1970 1980 1990 2000
KIAA05 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
::::::::::::::::::::::::::::: :::::::::::::::::::::::::
gi|109 PLDSNQTSDVLRFVLEQYNALSWLTCDPAIQDRRSCLPIHFVVLNQLYNFIMNML
2120 2130 2140 2150 2160 2170
>>gi|194217212|ref|XP_001500884.2| PREDICTED: mediator c (2165 aa)
initn: 8941 init1: 8941 opt: 13147 Z-score: 12285.7 bits: 2286.9 E(): 0
Smith-Waterman score: 13147; 95.960% identity (98.603% similar) in 2005 aa overlap (1-2005:163-2165)
10 20 30
KIAA05 GDSNVCTSVEINQHQPVYLLSEEHITLAQQ
::::::::::::::::::::::::::::::
gi|194 GKWFVKPYEKDEKPINKSEHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHITLAQQ
140 150 160 170 180 190
40 50 60 70 80 90
KIAA05 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
::::::::: :::::::::::::::::::::::::::::::::: :::::::::::::::
gi|194 SNSPFQVILSPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISSCLKEMSEEKQEDMDW
200 210 220 230 240 250
100 110 120 130 140 150
KIAA05 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
::::::::::::::::::::::::::::::::::: :::.:::.::::::::::::::::
gi|194 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSSVGSSHCSASCLGVHQVPASTRDPA
260 270 280 290 300 310
160 170 180 190 200 210
KIAA05 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
::::::::::::::::::::::.:::::.:::::::::::::::::::::::::::::::
gi|194 MSSVTLTPPTSPEEVQTVDPQSAQKWVKLSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
320 330 340 350 360 370
220 230 240 250 260 270
KIAA05 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
::::::::::::::::::::::::: .: ::::::::::::::::::::::::: :: ::
gi|194 WQECNMNRAQNKRKYSASSGGLCEEESADKVASWDFVEATQRTNCSCLRHKNLKPRNPGQ
380 390 400 410 420 430
280 290 300 310 320 330
KIAA05 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
:::::::.::::.:::::::::::::::::::::::::::::.:::::::.:::::::::
gi|194 QGQAPSLSQQQQVLPKHKTNEKQEKSEKPQKRPLTPFHHRVSISDDVGMDTDSASQRLVI
440 450 460 470 480 490
340 350 360 370 380 390
KIAA05 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 SAPDSQVRFSSIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
500 510 520 530 540 550
400 410 420 430 440 450
KIAA05 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
:::::::::::::::::::::::::::: :.:::::::.:::::::::::::::::::::
gi|194 FYQMPTPDPLVPSKPMEDRIDSLSQSFPAQFQEAVEPTIYVGTAVNLEEDEANIAWKYYK
560 570 580 590 600 610
460 470 480 490 500 510
KIAA05 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 VPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
620 630 640 650 660 670
520 530 540 550 560 570
KIAA05 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
: ::::.:::::::::::::::::::::::::::::::.::::::::::::: :::::::
gi|194 QYLSAISSDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNNEREAGKKHKVEDGPSSVTVLS
680 690 700 710 720 730
580 590 600 610 620 630
KIAA05 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
: .:::::::::::::::::..::::::::::::::::::::::::::::::::::::::
gi|194 HAKDAMSLFSPSIKQDAPRPSGHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
740 750 760 770 780 790
640 650 660 670 680 690
KIAA05 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
:::::::::..:::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 KSANGSDDKSGCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
800 810 820 830 840 850
700 710 720 730 740 750
KIAA05 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
gi|194 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQVLVGCSMFAP
860 870 880 890 900 910
760 770 780 790 800 810
KIAA05 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
::::::: :::::::::::::::::::::::: :::..::::.::::.:::::: :::::
gi|194 LKTLPSQCLPPIKLPEECIYRQSWTVGKLELLPSGPALPFIKDGDGSTMDQEYGPAYTPQ
920 930 940 950 960 970
820 830 840 850 860 870
KIAA05 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
980 990 1000 1010 1020 1030
880 890 900 910 920 930
KIAA05 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
1040 1050 1060 1070 1080 1090
940 950 960 970 980 990
KIAA05 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
gi|194 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTECGKEA
1100 1110 1120 1130 1140 1150
1000 1010 1020 1030 1040 1050
KIAA05 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
::::::::::::::::::::::::: :.:::::::::::::::::::::::::: :::::
gi|194 EKRFEALRATSAEHVNGGLKESEKLPDELILLLQDQCTNLFSPFGAADQDPFPKIGVISN
1160 1170 1180 1190 1200 1210
1060 1070 1080 1090 1100 1110
KIAA05 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
gi|194 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDLSMQCSQDIL
1220 1230 1240 1250 1260 1270
1120 1130 1140 1150 1160 1170
KIAA05 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
1280 1290 1300 1310 1320 1330
1180 1190 1200 1210 1220 1230
KIAA05 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 YDYDFLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
1340 1350 1360 1370 1380 1390
1240 1250 1260 1270 1280 1290
KIAA05 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 RLGQHRPISRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
1400 1410 1420 1430 1440 1450
1300 1310 1320 1330 1340 1350
KIAA05 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
::::::: ::::::::::::::::::::::: ::::::::::::::::::::::: :::
gi|194 LGPYLASQPLDSSLLSQPNLVAPTSQSLITPSQMTNTGNANTPSATLASAASSTM--TSG
1460 1470 1480 1490 1500 1510
1360 1370 1380 1390 1400 1410
KIAA05 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
::.:.:::.:::::::.:::::::::::::::::::::::::::.::..::::::::.::
gi|194 VAMSSSVAAANSTLTTTSTSSSSSSNLNSGVSSNKLPSFPPFGSINSSTAGSMSTQASTV
1520 1530 1540 1550 1560 1570
1420 1430 1440 1450 1460 1470
KIAA05 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
:.:::::::..:.:: :::::::::::::::::::::::::::::::::::::.::::::
gi|194 QNGQLGGQQSAAVQTPGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAI
1580 1590 1600 1610 1620 1630
1480 1490 1500 1510 1520 1530
KIAA05 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
:::::::::::: :::::::.:::::::::::::::::: ::::::::::.:::::::::
gi|194 VVYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPSHIKSTVSVQIVPCQYLLQPV
1640 1650 1660 1670 1680 1690
1540 1550 1560 1570 1580 1590
KIAA05 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
:::::.:: ::::::::::::::::::::::::::::::::::::::::.::::::::::
gi|194 KHEDRQIYTQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRL
1700 1710 1720 1730 1740 1750
1600 1610 1620 1630 1640 1650
KIAA05 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 YTPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
1760 1770 1780 1790 1800 1810
1660 1670 1680 1690 1700 1710
KIAA05 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
:::::::::::::.:::.::::::::::::::::::.:::::::::::::::::::::::
gi|194 INIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSFPWRVVIGRLGRIGHGELKDWSCL
1820 1830 1840 1850 1860 1870
1720 1730 1740 1750 1760 1770
KIAA05 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
1880 1890 1900 1910 1920 1930
1780 1790 1800 1810 1820 1830
KIAA05 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
gi|194 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADAMGIFD
1940 1950 1960 1970 1980 1990
1840 1850 1860 1870 1880 1890
KIAA05 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
::::::::::::::::::::::::::::::::::::::::::.:::::::: :.:: :::
gi|194 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNIL
2000 2010 2020 2030 2040 2050
1900 1910 1920 1930 1940 1950
KIAA05 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
2060 2070 2080 2090 2100 2110
1960 1970 1980 1990 2000
KIAA05 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
::::::::::::::::::::::::::::: :::::::::::::::::::::::::
gi|194 PLDSNQTSDVLRFVLEQYNALSWLTCDPAIQDRRSCLPIHFVVLNQLYNFIMNML
2120 2130 2140 2150 2160
>>gi|194675789|ref|XP_603205.4| PREDICTED: similar to me (2332 aa)
initn: 13124 init1: 13124 opt: 13124 Z-score: 12263.7 bits: 2282.9 E(): 0
Smith-Waterman score: 13124; 95.561% identity (98.504% similar) in 2005 aa overlap (1-2005:328-2332)
10 20 30
KIAA05 GDSNVCTSVEINQHQPVYLLSEEHITLAQQ
::::::::::::::::::::::::::::::
gi|194 GKWFVKPYEKDEKPINKSEHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHITLAQQ
300 310 320 330 340 350
40 50 60 70 80 90
KIAA05 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
::::::::: :::::::::::::::::::::::::::::::::: :::::::::::::::
gi|194 SNSPFQVILSPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISSCLKEMSEEKQEDMDW
360 370 380 390 400 410
100 110 120 130 140 150
KIAA05 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
::::::::::::::::::::::::::::::::::: :::.:::.::::::::::::::::
gi|194 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSSVGSSHCSASCLGVHQVPASTRDPA
420 430 440 450 460 470
160 170 180 190 200 210
KIAA05 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
::::::::::::::::::::::.:::.:::::::::.:::::::::::::::::::::::
gi|194 MSSVTLTPPTSPEEVQTVDPQSAQKWIKFSSVSDGFSSDSTSHHGGKIPRKLANHVVDRV
480 490 500 510 520 530
220 230 240 250 260 270
KIAA05 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
::::::::::::::::::::::::: :: ::::::::::::::::::::::::: :: ::
gi|194 WQECNMNRAQNKRKYSASSGGLCEEETADKVASWDFVEATQRTNCSCLRHKNLKPRNPGQ
540 550 560 570 580 590
280 290 300 310 320 330
KIAA05 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
:::::::.::::.:::::::::::::::::::::::::::::::::::::.:::::::::
gi|194 QGQAPSLSQQQQVLPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDTDSASQRLVI
600 610 620 630 640 650
340 350 360 370 380 390
KIAA05 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 SAPDSQVRFTNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
660 670 680 690 700 710
400 410 420 430 440 450
KIAA05 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
::::::::::.::::.:: ::::::::: :.:::::::.:::::::::::::::::::::
gi|194 FYQMPTPDPLIPSKPVEDGIDSLSQSFPAQFQEAVEPTIYVGTAVNLEEDEANIAWKYYK
720 730 740 750 760 770
460 470 480 490 500 510
KIAA05 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
:::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 VPKKKDLEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
780 790 800 810 820 830
520 530 540 550 560 570
KIAA05 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
: :::::::.::::::::::::::::::::::::::::.::::::::::::: :::::::
gi|194 QYLSAIASDSEQEPKIDPYAFVEGDEEFLFPDKKDRQNNEREAGKKHKVEDGPSSVTVLS
840 850 860 870 880 890
580 590 600 610 620 630
KIAA05 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
::::::::::::::::::::..::::::::::::::::::::::::::::::::::::::
gi|194 HEEDAMSLFSPSIKQDAPRPAGHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
900 910 920 930 940 950
640 650 660 670 680 690
KIAA05 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 KSANGSDDKSSCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
960 970 980 990 1000 1010
700 710 720 730 740 750
KIAA05 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
:::::::::::::::.::::::::::::::::::::::::::::::::::.:::::::::
gi|194 MDTTPGGTVLEGNSSGIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQVLVGCSMFAP
1020 1030 1040 1050 1060 1070
760 770 780 790 800 810
KIAA05 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
::::::: ::::::::::::::::::::::::::::.::::::::::.:::::: :::::
gi|194 LKTLPSQCLPPIKLPEECIYRQSWTVGKLELLSSGPTMPFIKEGDGSTMDQEYGPAYTPQ
1080 1090 1100 1110 1120 1130
820 830 840 850 860 870
KIAA05 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
1140 1150 1160 1170 1180 1190
880 890 900 910 920 930
KIAA05 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
1200 1210 1220 1230 1240 1250
940 950 960 970 980 990
KIAA05 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
gi|194 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTECGKEA
1260 1270 1280 1290 1300 1310
1000 1010 1020 1030 1040 1050
KIAA05 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
::::::::::::::::::::::::: :.:::::::::::::::::::::::::: :: .:
gi|194 EKRFEALRATSAEHVNGGLKESEKLPDELILLLQDQCTNLFSPFGAADQDPFPKIGVTNN
1320 1330 1340 1350 1360 1370
1060 1070 1080 1090 1100 1110
KIAA05 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
gi|194 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSVQCSQDIL
1380 1390 1400 1410 1420 1430
1120 1130 1140 1150 1160 1170
KIAA05 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
1440 1450 1460 1470 1480 1490
1180 1190 1200 1210 1220 1230
KIAA05 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
::.:.::::::::::::::::::::::::::::::::::::::::::::::::::::: :
gi|194 YDFDFLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYECC
1500 1510 1520 1530 1540 1550
1240 1250 1260 1270 1280 1290
KIAA05 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
:::::::.:::::::::::::::::::::::::::::::::::.::::::::::::::::
gi|194 RLGQHRPISRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNSEAFSKLKLYAQVCRYD
1560 1570 1580 1590 1600 1610
1300 1310 1320 1330 1340 1350
KIAA05 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
::::::: :::::::::::::::::::::::::::.:::::::::::::..:::::..::
gi|194 LGPYLASQPLDSSLLSQPNLVAPTSQSLITPPQMTSTGNANTPSATLASTVSSTMTMSSG
1620 1630 1640 1650 1660 1670
1360 1370 1380 1390 1400 1410
KIAA05 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
::.:.:::::::::::.::::: :::::::.::::::::::::.:::.:.:::::::.::
gi|194 VAMSSSVATANSTLTTTSTSSSLSSNLNSGMSSNKLPSFPPFGTMNSSATGSMSTQASTV
1680 1690 1700 1710 1720 1730
1420 1430 1440 1450 1460 1470
KIAA05 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
..::::: ::::::::::::::.::::::::::::::::::::::::::::.::::::
gi|194 PNSQLGGQPPSALQTAGISGESSSVPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAI
1740 1750 1760 1770 1780 1790
1480 1490 1500 1510 1520 1530
KIAA05 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
:::::::::::: :::::::.::::::::::::::::::::::.::::::.:::::::::
gi|194 VVYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKNTVSVQIVPCQYLLQPV
1800 1810 1820 1830 1840 1850
1540 1550 1560 1570 1580 1590
KIAA05 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
:::::.:: ::::::::::::::::::::::::::::::::::::::::.::::::::::
gi|194 KHEDRQIYTQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRL
1860 1870 1880 1890 1900 1910
1600 1610 1620 1630 1640 1650
KIAA05 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
:.::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
gi|194 YTPPFILAPVKDKQTELGETFGEPGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
1920 1930 1940 1950 1960 1970
1660 1670 1680 1690 1700 1710
KIAA05 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
:::::::::::::.:::.::::::::::::::::::::::::::::::::::::::::::
gi|194 INIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
1980 1990 2000 2010 2020 2030
1720 1730 1740 1750 1760 1770
KIAA05 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
2040 2050 2060 2070 2080 2090
1780 1790 1800 1810 1820 1830
KIAA05 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
.:::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
gi|194 STLNMQTSQLNTPQDISCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
2100 2110 2120 2130 2140 2150
1840 1850 1860 1870 1880 1890
KIAA05 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
::::::::::::::::::::::::::::::::::::::::::.:::::::: :.:: :::
gi|194 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNIL
2160 2170 2180 2190 2200 2210
1900 1910 1920 1930 1940 1950
KIAA05 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
2220 2230 2240 2250 2260 2270
1960 1970 1980 1990 2000
KIAA05 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
::::::::::::::::::::::::::::: :::::::::::::::::::::::::
gi|194 PLDSNQTSDVLRFVLEQYNALSWLTCDPAIQDRRSCLPIHFVVLNQLYNFIMNML
2280 2290 2300 2310 2320 2330
>>gi|73966750|ref|XP_537704.2| PREDICTED: similar to Thy (2182 aa)
initn: 7570 init1: 7570 opt: 13103 Z-score: 12244.5 bits: 2279.3 E(): 0
Smith-Waterman score: 13103; 96.010% identity (98.304% similar) in 2005 aa overlap (1-2005:179-2182)
10 20 30
KIAA05 GDSNVCTSVEINQHQPVYLLSEEHITLAQQ
::::::::::::::::::::::::::::::
gi|739 GKWFVKPYEKDEKPINKSEHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHITLAQQ
150 160 170 180 190 200
40 50 60 70 80 90
KIAA05 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
::::::::: :::::::::::::::::::::::::::::::::: :::::::::::::::
gi|739 SNSPFQVILSPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISSCLKEMSEEKQEDMDW
210 220 230 240 250 260
100 110 120 130 140 150
KIAA05 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
::::::::::::::::::::::::::::::::::: :::.:::.::::::::::::::::
gi|739 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSSVGSSHCSASCLGVHQVPASTRDPA
270 280 290 300 310 320
160 170 180 190 200 210
KIAA05 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
::::::::::::::::::::::.:::::::::::::.:::::::::::::::::::::::
gi|739 MSSVTLTPPTSPEEVQTVDPQSAQKWVKFSSVSDGFSSDSTSHHGGKIPRKLANHVVDRV
330 340 350 360 370 380
220 230 240 250 260 270
KIAA05 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
:::::::::::::::::::::: :: ::::::::::::::::::::::.:: :: ::
gi|739 WQECNMNRAQNKRKYSASSGGLSEEEIPDKVASWDFVEATQRTNCSCLRHKSLKPRNPGQ
390 400 410 420 430 440
280 290 300 310 320 330
KIAA05 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
:::::::.::::.:::::::::::::::::::::::::::::::::::::.:::::::::
gi|739 QGQAPSLSQQQQVLPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDTDSASQRLVI
450 460 470 480 490 500
340 350 360 370 380 390
KIAA05 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
510 520 530 540 550 560
400 410 420 430 440 450
KIAA05 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
:::::::::::::::::::::::::::: :.:::::::::::::::::::::::::::::
gi|739 FYQMPTPDPLVPSKPMEDRIDSLSQSFPAQFQEAVEPTVYVGTAVNLEEDEANIAWKYYK
570 580 590 600 610 620
460 470 480 490 500 510
KIAA05 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 VPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
630 640 650 660 670 680
520 530 540 550 560 570
KIAA05 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
: ::::::::::: ::::::::::::::::::::::::::::: :::::::: :::::::
gi|739 QYLSAIASDAEQESKIDPYAFVEGDEEFLFPDKKDRQNSEREAVKKHKVEDGPSSVTVLS
690 700 710 720 730 740
580 590 600 610 620 630
KIAA05 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
750 760 770 780 790 800
640 650 660 670 680 690
KIAA05 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
:::::.:::.: :::::::::::::::::::::::::::::::::::::::::.::::::
gi|739 KSANGTDDKSSSKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMSNKEYGS
810 820 830 840 850 860
700 710 720 730 740 750
KIAA05 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
:: :::::::::::::::.:::::::::::::::::::::::::::::::.:::::::::
gi|739 MDITPGGTVLEGNSSSIGTQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQVLVGCSMFAP
870 880 890 900 910 920
760 770 780 790 800 810
KIAA05 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
::.:::: :::::::::::::::::::::::: :::..:::::::::..::::: :::::
gi|739 LKSLPSQCLPPIKLPEECIYRQSWTVGKLELLPSGPAVPFIKEGDGSTIDQEYGPAYTPQ
930 940 950 960 970 980
820 830 840 850 860 870
KIAA05 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
gi|739 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPR-AGGPASAQGSVKYENS
990 1000 1010 1020 1030 1040
880 890 900 910 920 930
KIAA05 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
1050 1060 1070 1080 1090 1100
940 950 960 970 980 990
KIAA05 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
::::::::::::::: ::::::::::::::::::::::::::::::::::::::.:::::
gi|739 MNIKGADVGVYIPDPMQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTECGKEA
1110 1120 1130 1140 1150 1160
1000 1010 1020 1030 1040 1050
KIAA05 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
::::::::::::::::::::::::. :.:::::::::::::::::::::::::. :::::
gi|739 EKRFEALRATSAEHVNGGLKESEKFPDELILLLQDQCTNLFSPFGAADQDPFPRIGVISN
1170 1180 1190 1200 1210 1220
1060 1070 1080 1090 1100 1110
KIAA05 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
1230 1240 1250 1260 1270 1280
1120 1130 1140 1150 1160 1170
KIAA05 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 RMLLFLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
1290 1300 1310 1320 1330 1340
1180 1190 1200 1210 1220 1230
KIAA05 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 YDYDFLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
1350 1360 1370 1380 1390 1400
1240 1250 1260 1270 1280 1290
KIAA05 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 RLGQHRPISRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
1410 1420 1430 1440 1450 1460
1300 1310 1320 1330 1340 1350
KIAA05 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
::::::: :::::::::::::::.:::::: :::::::::::::::::::::::.:::::
gi|739 LGPYLASQPLDSSLLSQPNLVAPASQSLITSPQMTNTGNANTPSATLASAASSTITVTSG
1470 1480 1490 1500 1510 1520
1360 1370 1380 1390 1400 1410
KIAA05 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
::.:.:::::::::::.::::::::::::::::::::::::::::::.:.::::::.:::
gi|739 VAMSSSVATANSTLTTTSTSSSSSSNLNSGVSSNKLPSFPPFGSMNSSATGSMSTQGNTV
1530 1540 1550 1560 1570 1580
1420 1430 1440 1450 1460 1470
KIAA05 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
:.:::::::.::::::::::::::::.::::::::::::::::::::::::::.::::::
gi|739 QNGQLGGQQSSALQTAGISGESSSLPAQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAI
1590 1600 1610 1620 1630 1640
1480 1490 1500 1510 1520 1530
KIAA05 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
:::::::::::: :::::::.:::::::::::::::::::::::::::::.:::::::::
gi|739 VVYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPV
1650 1660 1670 1680 1690 1700
1540 1550 1560 1570 1580 1590
KIAA05 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
:::::.:: ::::::::::::::::::::::::::::::::::::::::.::::::::::
gi|739 KHEDRQIYTQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRL
1710 1720 1730 1740 1750 1760
1600 1610 1620 1630 1640 1650
KIAA05 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 YTPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
1770 1780 1790 1800 1810 1820
1660 1670 1680 1690 1700 1710
KIAA05 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
:::::::::::::.:::.:::::::::::::::::::::::::::::::::::::::: :
gi|739 INIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSSL
1830 1840 1850 1860 1870 1880
1720 1730 1740 1750 1760 1770
KIAA05 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
1890 1900 1910 1920 1930 1940
1780 1790 1800 1810 1820 1830
KIAA05 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
1950 1960 1970 1980 1990 2000
1840 1850 1860 1870 1880 1890
KIAA05 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
::::::::::::::::::::::::::::::::::::::::::.:::::::: :.:: :::
gi|739 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNIL
2010 2020 2030 2040 2050 2060
1900 1910 1920 1930 1940 1950
KIAA05 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
2070 2080 2090 2100 2110 2120
1960 1970 1980 1990 2000
KIAA05 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
::::::::::::::::::::::::::::: :::::::::::::::::::::::::
gi|739 PLDSNQTSDVLRFVLEQYNALSWLTCDPAIQDRRSCLPIHFVVLNQLYNFIMNML
2130 2140 2150 2160 2170 2180
>>gi|81910189|sp|Q5SWW4.1|MED13_MOUSE RecName: Full=Medi (2171 aa)
initn: 8786 init1: 5088 opt: 12903 Z-score: 12057.5 bits: 2244.7 E(): 0
Smith-Waterman score: 12903; 93.416% identity (98.404% similar) in 2005 aa overlap (1-2005:170-2171)
10 20 30
KIAA05 GDSNVCTSVEINQHQPVYLLSEEHITLAQQ
::::::::::::::::::::::::.:::::
gi|819 GKWFVKPYEKDEKPINKSEHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHVTLAQQ
140 150 160 170 180 190
40 50 60 70 80 90
KIAA05 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
::::::::: ::::::::::::::::::::::::::::::::::: :::::::::.::::
gi|819 SNSPFQVILSPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCGLKEMSEEKQDDMDW
200 210 220 230 240 250
100 110 120 130 140 150
KIAA05 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
::::::::::::::::::::::::::::::::.:: ::..:::.::::.:::::::::::
gi|819 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPAPSSVGASHCSASCLGIHQVPASTRDPA
260 270 280 290 300 310
160 170 180 190 200 210
KIAA05 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
::::::::::::::::::::::.:::::::::::::..::::::::::::::::::::::
gi|819 MSSVTLTPPTSPEEVQTVDPQSAQKWVKFSSVSDGFSTDSTSHHGGKIPRKLANHVVDRV
320 330 340 350 360 370
220 230 240 250 260 270
KIAA05 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
:::::::: ::::::::.:.::::: :: :.. ::::::::::.:::::::.::.::.::
gi|819 WQECNMNRLQNKRKYSATSSGLCEEETADKIGCWDFVEATQRTSCSCLRHKSLKTRNTGQ
380 390 400 410 420 430
280 290 300 310 320 330
KIAA05 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
::::::::::::.::::::::::.:::::::::::::::::::::..:::.:::::::::
gi|819 QGQAPSLGQQQQVLPKHKTNEKQDKSEKPQKRPLTPFHHRVSVSDEIGMDTDSASQRLVI
440 450 460 470 480 490
340 350 360 370 380 390
KIAA05 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
:: ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
gi|819 SAADSQVRFSNIRTNDVAKTPQMHGTELANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
500 510 520 530 540 550
400 410 420 430 440 450
KIAA05 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
::::::::::::.:::::::::::::::: .::::::::::::::.:::::::.::::::
gi|819 FYQMPTPDPLVPTKPMEDRIDSLSQSFPPPFQEAVEPTVYVGTAVSLEEDEANVAWKYYK
560 570 580 590 600 610
460 470 480 490 500 510
KIAA05 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
::::::::::::::.:::::::::::::::::::::::::::::::::::.::::::::
gi|819 VPKKKDVEFLPPQLPNDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDEIVQQYQIKN
620 630 640 650 660 670
520 530 540 550 560 570
KIAA05 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
: :::::::.::::::::::::::::::.: :::::::::::::::::::::::.:::::
gi|819 QYLSAIASDTEQEPKIDPYAFVEGDEEFIFTDKKDRQNSEREAGKKHKVEDGTSAVTVLS
680 690 700 710 720 730
580 590 600 610 620 630
KIAA05 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
:::::::::::: ::::::::.::::::::::::::::::::::::::::::::::::::
gi|819 HEEDAMSLFSPS-KQDAPRPTNHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
740 750 760 770 780 790
640 650 660 670 680 690
KIAA05 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
:::.::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 KSASGSDDKASSKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
800 810 820 830 840 850
700 710 720 730 740 750
KIAA05 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
.::.::::::::::::.:.::.:::.::::::::::::::::::::::::.:::::::::
gi|819 VDTAPGGTVLEGNSSSVGTQFRIEVEEGFCSPKPSEIKDFSYVYKPENCQVLVGCSMFAP
860 870 880 890 900 910
760 770 780 790 800 810
KIAA05 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
::::::. ::::::::::.::::::::::.:: :::::::::::::::.::.:: :::::
gi|819 LKTLPSHCLPPIKLPEECVYRQSWTVGKLDLLPSGPSMPFIKEGDGSNLDQDYGPAYTPQ
920 930 940 950 960 970
820 830 840 850 860 870
KIAA05 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
::.:::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
gi|819 THASFGMPPSSAPPSNGGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
980 990 1000 1010 1020 1030
880 890 900 910 920 930
KIAA05 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
1040 1050 1060 1070 1080 1090
940 950 960 970 980 990
KIAA05 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
1100 1110 1120 1130 1140 1150
1000 1010 1020 1030 1040 1050
KIAA05 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
:::::::::.:.:.::::::::::. :.:::::::::::::::::::::::::: :. ::
gi|819 EKRFEALRASSVENVNGGLKESEKVPDELILLLQDQCTNLFSPFGAADQDPFPKVGISSN
1160 1170 1180 1190 1200 1210
1060 1070 1080 1090 1100 1110
KIAA05 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
::::::::::.:: :::::::::::::::::::::::.:::::::.:.::.:.:::::::
gi|819 WVRVEERDCCSDCCLALEHGRQFMDNMSGGKVDEALVRSSCLHPWAKQNDASVQCSQDIL
1220 1230 1240 1250 1260 1270
1120 1130 1140 1150 1160 1170
KIAA05 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
1280 1290 1300 1310 1320 1330
1180 1190 1200 1210 1220 1230
KIAA05 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
::::.::::::::::::.::::::::::::::::::::::::::::.:::::::::::::
gi|819 YDYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESC
1340 1350 1360 1370 1380 1390
1240 1250 1260 1270 1280 1290
KIAA05 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
:::::::.:::::::::.::.:::::::::.:.:::::::::::::::::::::::::::
gi|819 RLGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYD
1400 1410 1420 1430 1440 1450
1300 1310 1320 1330 1340 1350
KIAA05 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
::::::: ::::::::::::::: .:::.: ::::::::::.::::::::::::::.:::
gi|819 LGPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSG
1460 1470 1480 1490 1500 1510
1360 1370 1380 1390 1400 1410
KIAA05 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
: :::::::::::::: :::::::.:.::::::::::::::::::....::::.::.::
gi|819 VPISTSVATANSTLTT--TSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTV
1520 1530 1540 1550 1560 1570
1420 1430 1440 1450 1460 1470
KIAA05 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
:::::::::.:.::.:::::::.::::::::::::::::::::::::::::::.::::::
gi|819 QSGQLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAI
1580 1590 1600 1610 1620 1630
1480 1490 1500 1510 1520 1530
KIAA05 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
:::::::::::: :::::::.:::::::::::::::::::::::::::::.:::::::::
gi|819 VVYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPV
1640 1650 1660 1670 1680 1690
1540 1550 1560 1570 1580 1590
KIAA05 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
::.::.:: :::::::::.::::::::::::::::::::::::::::::.::::::::::
gi|819 KHDDRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRL
1700 1710 1720 1730 1740 1750
1600 1610 1620 1630 1640 1650
KIAA05 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 YTPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
1760 1770 1780 1790 1800 1810
1660 1670 1680 1690 1700 1710
KIAA05 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
:::::::::::::.:::.::::::::::::::::::::::::::::::::::::::::::
gi|819 INIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
1820 1830 1840 1850 1860 1870
1720 1730 1740 1750 1760 1770
KIAA05 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
1880 1890 1900 1910 1920 1930
1780 1790 1800 1810 1820 1830
KIAA05 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 TTLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
1940 1950 1960 1970 1980 1990
1840 1850 1860 1870 1880 1890
KIAA05 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
:::::::::::::::::::::.::::::::::::::::::::.:::::::: :.:: :::
gi|819 LLDTGDDLDPDIINILPASPTASPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNIL
2000 2010 2020 2030 2040 2050
1900 1910 1920 1930 1940 1950
KIAA05 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
2060 2070 2080 2090 2100 2110
1960 1970 1980 1990 2000
KIAA05 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
:::::::::::::::::::::::::::::.::::::::.::::::::::::::::
gi|819 PLDSNQTSDVLRFVLEQYNALSWLTCDPAVQDRRSCLPVHFVVLNQLYNFIMNML
2120 2130 2140 2150 2160 2170
>>gi|149053743|gb|EDM05560.1| thyroid hormone receptor a (2040 aa)
initn: 8858 init1: 5064 opt: 12888 Z-score: 12043.9 bits: 2242.1 E(): 0
Smith-Waterman score: 12888; 93.317% identity (98.304% similar) in 2005 aa overlap (1-2005:39-2040)
10 20 30
KIAA05 GDSNVCTSVEINQHQPVYLLSEEHITLAQQ
::::::::::::::::::::::::.:::::
gi|149 GKWFVKPYEKDEKPINKSEHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHVTLAQQ
10 20 30 40 50 60
40 50 60 70 80 90
KIAA05 SNSPFQVILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDW
::::::::: ::::::::::::::::::::::::::::::::::: ::::::::::::::
gi|149 SNSPFQVILSPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCGLKEMSEEKQEDMDW
70 80 90 100 110 120
100 110 120 130 140 150
KIAA05 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPA
::::::::::::::::::::::::::::::::::: :::.:::.::::.:::::::::::
gi|149 EDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSSVGSSHCSASCLGIHQVPASTRDPA
130 140 150 160 170 180
160 170 180 190 200 210
KIAA05 MSSVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRV
::::::::::::::::.:::::.:::::::::::::..::::::::::::::::::::::
gi|149 MSSVTLTPPTSPEEVQSVDPQSAQKWVKFSSVSDGFSTDSTSHHGGKIPRKLANHVVDRV
190 200 210 220 230 240
220 230 240 250 260 270
KIAA05 WQECNMNRAQNKRKYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQ
:::::::: ::::::::.:.::::: :: :..:::::::::::.:::::::.::.::.::
gi|149 WQECNMNRLQNKRKYSATSSGLCEEETADKIGSWDFVEATQRTSCSCLRHKSLKTRNTGQ
250 260 270 280 290 300
280 290 300 310 320 330
KIAA05 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVGMDADSASQRLVI
::::::::::::::::::::::::::::::::::::::::::.:::.:::.:::::::::
gi|149 QGQAPSLGQQQQILPKHKTNEKQEKSEKPQKRPLTPFHHRVSISDDIGMDTDSASQRLVI
310 320 330 340 350 360
340 350 360 370 380 390
KIAA05 SAPDSQVRFSNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
:: ::::::.:::::::::::::::::.::::::::::::::::::::::::::::::::
gi|149 SAADSQVRFTNIRTNDVAKTPQMHGTELANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQH
370 380 390 400 410 420
400 410 420 430 440 450
KIAA05 FYQMPTPDPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYK
::::::::::::.:::::::::::::::: .::::::::::::::.:::::::.::::::
gi|149 FYQMPTPDPLVPTKPMEDRIDSLSQSFPPPFQEAVEPTVYVGTAVSLEEDEANVAWKYYK
430 440 450 460 470 480
460 470 480 490 500 510
KIAA05 FPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKN
::::::::::::::.:::::::::::::::::::::::::::::::::::.::::::::
gi|149 VPKKKDVEFLPPQLPNDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDEIVQQYQIKN
490 500 510 520 530 540
520 530 540 550 560 570
KIAA05 QCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLS
: :::::::.::::::::::::::::::.: :::::::::::::::::::::::.:::::
gi|149 QYLSAIASDTEQEPKIDPYAFVEGDEEFIFTDKKDRQNSEREAGKKHKVEDGTSAVTVLS
550 560 570 580 590 600
580 590 600 610 620 630
KIAA05 HEEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
:::::::::::: :::::::..::::::::::::::::::::::::::::::::::::::
gi|149 HEEDAMSLFSPS-KQDAPRPANHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSK
610 620 630 640 650 660
640 650 660 670 680 690
KIAA05 KSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
:::.::::::: ::::::.:::::::::::::::::::::::::::::::::::::::::
gi|149 KSASGSDDKASSKESKTGSLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGS
670 680 690 700 710 720
700 710 720 730 740 750
KIAA05 MDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAP
:: :::::::::.:::.:.::.:::.::::::::::::::::::::::::.:::::::::
gi|149 MDPTPGGTVLEGSSSSVGTQFRIEVEEGFCSPKPSEIKDFSYVYKPENCQVLVGCSMFAP
730 740 750 760 770 780
760 770 780 790 800 810
KIAA05 LKTLPSQYLPPIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEYGTAYTPQ
::::::. ::::::::::.::::::::::.:: :::::::::::::::.::.:: :::::
gi|149 LKTLPSHCLPPIKLPEECVYRQSWTVGKLDLLPSGPSMPFIKEGDGSNLDQDYGPAYTPQ
790 800 810 820 830 840
820 830 840 850 860 870
KIAA05 THTSFGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
:::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
gi|149 IHTSFGMPPSSAPPSNGGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS
850 860 870 880 890 900
880 890 900 910 920 930
KIAA05 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 DLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCN
910 920 930 940 950 960
940 950 960 970 980 990
KIAA05 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 MNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEA
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
KIAA05 EKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISN
:::::::::.:.:.:::.::::::. :.::::::::::::::::::::.:::::.:. ::
gi|149 EKRFEALRASSVENVNGSLKESEKVPDELILLLQDQCTNLFSPFGAADHDPFPKAGISSN
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
KIAA05 WVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLHPWSKRNDVSMQCSQDIL
::::::::::.:: :::::::::::::::::::::::.:::::::.:.::.:.:::::::
gi|149 WVRVEERDCCSDCCLALEHGRQFMDNMSGGKVDEALVRSSCLHPWAKQNDASVQCSQDIL
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
KIAA05 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 RMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLG
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
KIAA05 YDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESC
::::.::::::::::::.::::::::::::::::::::::::::::.:::::::::::::
gi|149 YDYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESC
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
KIAA05 RLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYD
:::::::.:::::::::.::.:::::::::.:.:::::::::::::::::::::::::::
gi|149 RLGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYD
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
KIAA05 LGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSG
::::::: ::::::::::::::: .:::.: ::::::::::.::::::::::::::.: :
gi|149 LGPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTLTPG
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
KIAA05 VAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTV
:::::::::::::::: :::::::...::::::::::::::::::....::::.:..::
gi|149 VAISTSVATANSTLTT--TSSSSSSSMSSGVSSNKLPSFPPFGSMNTSGTGSMSAQGSTV
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
KIAA05 QSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAI
:::::::::.:.::.:::::::.::::::::::::::::::::::::::::::.::::::
gi|149 QSGQLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAI
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
KIAA05 VVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPV
:::::::::::: ::::.::.:::::::::::::.:::::::::::::::.:::::::::
gi|149 VVYIIDPFTYENKDESTSSSNVWTLGLLRCFLEMLQTLPPHIKSTVSVQIVPCQYLLQPV
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
KIAA05 KHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRL
::.::.:: ::::::::::::::::::::::::::::::::::::::::.::::::::::
gi|149 KHDDRQIYSQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRL
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
KIAA05 YAPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 YTPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCI
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
KIAA05 INIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
:::::::::::::.:::.::::::::::::::::::::::::::::::::::::::::::
gi|149 INIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCL
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
KIAA05 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 LSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRS
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
KIAA05 TTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 TTLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFD
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
KIAA05 LLDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNIL
::::::::::::::::::::: ::::::::::::::::::::.:::::::: :.:: :::
gi|149 LLDTGDDLDPDIINILPASPTTSPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNIL
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940 1950
KIAA05 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 QQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSH
1930 1940 1950 1960 1970 1980
1960 1970 1980 1990 2000
KIAA05 PLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML
::::::::::::::::::::::::::::: :::::::::::::::::::::::::
gi|149 PLDSNQTSDVLRFVLEQYNALSWLTCDPAIQDRRSCLPIHFVVLNQLYNFIMNML
1990 2000 2010 2020 2030 2040
2005 residues in 1 query sequences
2693465022 residues in 7827732 library sequences
Tcomplib [34.26] (8 proc)
start: Thu Mar 5 08:36:25 2009 done: Thu Mar 5 08:40:53 2009
Total Scan time: 2289.010 Total Display time: 3.310
Function used was FASTA [version 34.26.5 April 26, 2007]