hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-05203789/chunk_1/iprscan-20080502-05203789.nocrc
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Query sequence: KIAA0520
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N 
--------      -----------                               -----    ------- ---
PF00211.10.ls Adenylate and Guanylate cyclase catalyt   531.2     1e-156   2
PF00211.10.fs Adenylate and Guanylate cyclase catalyt   527.5   1.3e-155   2

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
PF00211.10.fs   1/2     396   584 ..     1   223 []   323.1  4.6e-94
PF00211.10.ls   1/2     396   584 ..     1   223 []   324.9  1.3e-94
PF00211.10.fs   2/2    1060  1255 ..     1   223 []   204.4  2.4e-58
PF00211.10.ls   2/2    1060  1255 ..     1   223 []   206.3  6.7e-59

Alignments of top-scoring domains:
PF00211.10.fs: domain 1 of 2, from 396 to 584: score 323.1, E = 4.6e-94
                   *->vyaqrydnVtilFaDIvGFTalssrhsvNngpeevvrlLNdlytrFD
                      +++q+ ++V+ilFaDIvGFT++s+++s    ++++v lLNdl++rFD
    KIAA0520   396    FKMQQIEEVSILFADIVGFTKMSANKS----AHALVGLLNDLFGRFD 438  

                   eLldehkfgvyKvKTIGDaYMvasGlppaadqtkLakklqldsaaHaakl
                   +L++e+  +++K+ T+GD+Y++++G+p++             +a+Ha+++
    KIAA0520   439 RLCEET--KCEKISTLGDCYYCVAGCPEP-------------RADHAYCC 473  

                   admALdmveaiqevnvehanrepPtvLyrGlrvRiGiHtGpVvaGviGlt
                   ++m+L+m++ai+++++e+++  +       +++R+G+HtG+V++G++G  
    KIAA0520   474 IEMGLGMIKAIEQFCQEKKE--M-------VNMRVGVHTGTVLCGILG-- 512  

                   akrprYdvwGdTVNlASRmEStGvpgsekIhvseetyrlLkeeesfefef
                   ++r+++dvw+++VNlA++mE++Gv+g  k+h+se+t+++L +++++e+++
    KIAA0520   513 MRRFKFDVWSNDVNLANLMEQLGVAG--KVHISEATAKYLDDRYEMEDGK 560  

                   aleprgeveVkGkgkpGeietYfLkg<-*
                   ++e++g++ V ++ k+  ++tY+++g   
    KIAA0520   561 VIERLGQSVVADQLKG--LKTYLISG    584  

PF00211.10.ls: domain 1 of 2, from 396 to 584: score 324.9, E = 1.3e-94
                   *->vyaqrydnVtilFaDIvGFTalssrhsvNngpeevvrlLNdlytrFD
                      +++q+ ++V+ilFaDIvGFT++s+++s    ++++v lLNdl++rFD
    KIAA0520   396    FKMQQIEEVSILFADIVGFTKMSANKS----AHALVGLLNDLFGRFD 438  

                   eLldehkfgvyKvKTIGDaYMvasGlppaadqtkLakklqldsaaHaakl
                   +L++e+  +++K+ T+GD+Y++++G+p++             +a+Ha+++
    KIAA0520   439 RLCEET--KCEKISTLGDCYYCVAGCPEP-------------RADHAYCC 473  

                   admALdmveaiqevnvehanrepPtvLyrGlrvRiGiHtGpVvaGviGlt
                   ++m+L+m++ai+++++e+++  +       +++R+G+HtG+V++G++G  
    KIAA0520   474 IEMGLGMIKAIEQFCQEKKE--M-------VNMRVGVHTGTVLCGILG-- 512  

                   akrprYdvwGdTVNlASRmEStGvpgsekIhvseetyrlLkeeesfefef
                   ++r+++dvw+++VNlA++mE++Gv+g  k+h+se+t+++L +++++e+++
    KIAA0520   513 MRRFKFDVWSNDVNLANLMEQLGVAG--KVHISEATAKYLDDRYEMEDGK 560  

                   aleprgeveVkGkgkpGeietYfLkg<-*
                   ++e++g++ V ++ k+  ++tY+++g   
    KIAA0520   561 VIERLGQSVVADQLKG--LKTYLISG    584  

PF00211.10.fs: domain 2 of 2, from 1060 to 1255: score 204.4, E = 2.4e-58
                   *->vyaqrydnVtilFaDIvGFTalssrhsvNngpeevvrlLNdlytrFD
                       y++ +d+ +++Fa+Iv+F +++++    +g+ e+ r+LN+l+++FD
    KIAA0520  1060    TYSKNHDSGGVIFASIVNFSEFYEENY--EGGKECYRVLNELIGDFD 1104 

                   eLldehkf.gvyKvKTIGDaYMvasGlppaadqtkLakklqldsaa.Haa
                   eLl+++ ++ ++K+KTIG +YM+asGl         a+ ++ + +++H++
    KIAA0520  1105 ELLSKPDYsSIEKIKTIGATYMAASGLNT-------AQAQDGSHPQeHLQ 1147 

                   kladmALdmveaiqevnvehanrepPtvLyrGlrvRiGiHtGpVvaGviG
                    l ++A +m+  ++ +n+  +   +       +++R+G ++Gp  aGviG
    KIAA0520  1148 ILFEFAKEMMRVVDDFNSNMLW-FN-------FKLRVGFNHGPLTAGVIG 1189 

                   ltakrprYdvwGdTVNlASRmEStGvpgsekIhvseetyrlLkeeesfef
                     + +  Yd+wGdTVN+ASRm++tGv    +I+vsee yr+L++ + ++f
    KIAA0520  1190 --TTKLLYDIWGDTVNIASRMDTTGVEC--RIQVSEESYRVLSKMG-YDF 1234 

                   efaleprgeveVkGkgkpGeietYfLkg<-*
                   ++    rg v+VkGkg+   ++tY+ +    
    KIAA0520  1235 DY----RGTVNVKGKGQ---MKTYLYPK    1255 

PF00211.10.ls: domain 2 of 2, from 1060 to 1255: score 206.3, E = 6.7e-59
                   *->vyaqrydnVtilFaDIvGFTalssrhsvNngpeevvrlLNdlytrFD
                       y++ +d+ +++Fa+Iv+F +++++    +g+ e+ r+LN+l+++FD
    KIAA0520  1060    TYSKNHDSGGVIFASIVNFSEFYEENY--EGGKECYRVLNELIGDFD 1104 

                   eLldehkf.gvyKvKTIGDaYMvasGlppaadqtkLakklqldsaa.Haa
                   eLl+++ ++ ++K+KTIG +YM+asGl         a+ ++ + +++H++
    KIAA0520  1105 ELLSKPDYsSIEKIKTIGATYMAASGLNT-------AQAQDGSHPQeHLQ 1147 

                   kladmALdmveaiqevnvehanrepPtvLyrGlrvRiGiHtGpVvaGviG
                    l ++A +m+  ++ +n+  +   +       +++R+G ++Gp  aGviG
    KIAA0520  1148 ILFEFAKEMMRVVDDFNSNMLW-FN-------FKLRVGFNHGPLTAGVIG 1189 

                   ltakrprYdvwGdTVNlASRmEStGvpgsekIhvseetyrlLkeeesfef
                     + +  Yd+wGdTVN+ASRm++tGv    +I+vsee yr+L++ + ++f
    KIAA0520  1190 --TTKLLYDIWGDTVNIASRMDTTGVEC--RIQVSEESYRVLSKMG-YDF 1234 

                   efaleprgeveVkGkgkpGeietYfLkg<-*
                   ++    rg v+VkGkg+   ++tY+ +    
    KIAA0520  1235 DY----RGTVNVKGKGQ---MKTYLYPK    1255 

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