# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/ah04654.fasta.nr -Q ../query/KIAA0476.ptfa /cdna2/lib/nr/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
KIAA0476, 1626 aa
vs /cdna2/lib/nr/nr library
2693465022 residues in 7827732 sequences
statistics sampled from 60000 to 7813983 sequences
Expectation_n fit: rho(ln(x))= 6.3758+/-0.000206; mu= 11.5973+/- 0.011
mean_var=138.4424+/-26.105, 0's: 33 Z-trim: 71 B-trim: 70 in 1/64
Lambda= 0.109003
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 41, opt: 29, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7827732)
gi|114559776|ref|XP_513830.2| PREDICTED: DENN/MADD (1777) 10802 1711.7 0
gi|158514814|sp|O75064.4|DEN4B_HUMAN RecName: Full (1496) 10250 1624.8 0
gi|194210753|ref|XP_001493908.2| PREDICTED: DENN/M (1497) 9763 1548.2 0
gi|194036128|ref|XP_001929547.1| PREDICTED: DENN/M (1493) 9685 1535.9 0
gi|74212787|dbj|BAE33359.1| unnamed protein produc (1510) 9655 1531.2 0
gi|158563806|sp|Q3U1Y4.2|DEN4B_MOUSE RecName: Full (1499) 9624 1526.4 0
gi|119573654|gb|EAW53269.1| hCG18235, isoform CRA_ (1391) 8359 1327.4 0
gi|55959246|emb|CAI14016.1| DENN/MADD domain conta (1384) 8321 1321.4 0
gi|194665315|ref|XP_584938.4| PREDICTED: similar t (1478) 7972 1266.6 0
gi|148683202|gb|EDL15149.1| DENN/MADD domain conta (1419) 7643 1214.8 0
gi|109465103|ref|XP_342288.3| PREDICTED: similar t (1493) 6831 1087.1 0
gi|29612686|gb|AAH49972.1| Dennd4b protein [Mus mu ( 986) 6170 983.0 0
gi|26251714|gb|AAH40460.1| Dennd4b protein [Mus mu ( 906) 5666 903.7 0
gi|40949903|gb|AAR97575.1| brain specific protein (1213) 5181 827.6 0
gi|73961661|ref|XP_537262.2| PREDICTED: similar to (1420) 4164 667.7 1.8e-188
gi|127799115|gb|AAH66102.2| Dennd4b protein [Mus m (1239) 3827 614.6 1.5e-172
gi|118095984|ref|XP_413911.2| PREDICTED: similar t (1870) 3614 581.3 2.4e-162
gi|148683201|gb|EDL15148.1| DENN/MADD domain conta ( 674) 3594 577.7 1e-161
gi|126277440|ref|XP_001375920.1| PREDICTED: simila (1881) 3580 576.0 9.8e-161
gi|74000570|ref|XP_852698.1| PREDICTED: similar to (1865) 3553 571.7 1.9e-159
gi|74000572|ref|XP_866185.1| PREDICTED: similar to (1867) 3553 571.7 1.9e-159
gi|74000576|ref|XP_866212.1| PREDICTED: similar to (1876) 3553 571.7 1.9e-159
gi|190337632|gb|AAI63551.1| Dennd4a protein [Danio (1712) 3539 569.5 8e-159
gi|94733230|emb|CAK03709.1| novel protein similar (1674) 3536 569.0 1.1e-158
gi|119901894|ref|XP_001251258.1| PREDICTED: simila (1863) 3535 568.9 1.3e-158
gi|158261607|dbj|BAF82981.1| unnamed protein produ ( 927) 3530 567.8 1.4e-158
gi|21749723|dbj|BAC03648.1| unnamed protein produc ( 928) 3530 567.8 1.4e-158
gi|116283771|gb|AAH28057.1| DENND4A protein [Homo ( 933) 3530 567.8 1.4e-158
gi|119598149|gb|EAW77743.1| hCG2039346, isoform CR ( 988) 3530 567.8 1.5e-158
gi|114657728|ref|XP_001174618.1| PREDICTED: c-myc (1860) 3532 568.4 1.8e-158
gi|114657726|ref|XP_001174614.1| PREDICTED: c-myc (1863) 3532 568.4 1.8e-158
gi|114657730|ref|XP_001174623.1| PREDICTED: c-myc (1865) 3532 568.4 1.8e-158
gi|114657724|ref|XP_523102.2| PREDICTED: c-myc pro (1906) 3532 568.4 1.9e-158
gi|109081564|ref|XP_001110040.1| PREDICTED: simila (1863) 3531 568.3 2e-158
gi|109081566|ref|XP_001109991.1| PREDICTED: simila (1865) 3531 568.3 2e-158
gi|109081562|ref|XP_001109950.1| PREDICTED: simila (1906) 3531 568.3 2.1e-158
gi|88909230|sp|Q7Z401.2|MYCPP_HUMAN RecName: Full= (1863) 3530 568.1 2.3e-158
gi|33330327|gb|AAQ10514.1| c-MYC promoter-binding (1865) 3530 568.1 2.3e-158
gi|221307568|ref|NP_001138295.1| DENN/MADD domain (1906) 3530 568.1 2.3e-158
gi|119598150|gb|EAW77744.1| hCG2039346, isoform CR (1908) 3530 568.1 2.3e-158
gi|194206550|ref|XP_001497695.2| PREDICTED: simila (1865) 3526 567.5 3.5e-158
gi|27469519|gb|AAH41706.1| DENN/MADD domain contai (1863) 3521 566.7 6.1e-158
gi|30268290|emb|CAD89960.1| hypothetical protein [ (1831) 3445 554.7 2.4e-154
gi|73971036|ref|XP_531948.2| PREDICTED: similar to (1896) 3239 522.4 1.4e-144
gi|109111452|ref|XP_001101451.1| PREDICTED: hypoth (1897) 3201 516.4 8.6e-143
gi|118341439|gb|AAI27591.1| LOC798528 protein [Dan ( 704) 3194 514.8 9.3e-143
gi|119579048|gb|EAW58644.1| DENN/MADD domain conta (1660) 3195 515.4 1.5e-142
gi|119579051|gb|EAW58647.1| DENN/MADD domain conta (1882) 3195 515.4 1.7e-142
gi|119579050|gb|EAW58646.1| DENN/MADD domain conta (1946) 3195 515.4 1.7e-142
gi|20073354|gb|AAH26996.1| Dennd4b protein [Mus mu ( 507) 3141 506.4 2.4e-140
>>gi|114559776|ref|XP_513830.2| PREDICTED: DENN/MADD dom (1777 aa)
initn: 6841 init1: 6259 opt: 10802 Z-score: 9180.2 bits: 1711.7 E(): 0
Smith-Waterman score: 10817; 97.258% identity (97.562% similar) in 1641 aa overlap (1-1626:149-1777)
10 20 30
KIAA04 RRRPRPGAGVGGVEKAGRAEERWVPGAAGA
::::::::::::::::::::::::::::::
gi|114 TQAGRERAADLWVAWGQCPEARAGWWEATWRRRPRPGAGVGGVEKAGRAEERWVPGAAGA
120 130 140 150 160 170
40 50 60 70 80 90
KIAA04 GRTEPAERAARQHSPRVAQRGGDAGTARISFHCAPRSAVLGRLFFLHSLPGRERRPSRVR
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::.
gi|114 GRAEPAERAARQHSPRVAQRGGDAGTARISFHCAPRSAVLGRLFFLHSLPGRERRPT---
180 190 200 210 220 230
100 110 120 130
KIAA04 HVWGRVAPPPA-GP----PARP-PSHPPAGR-----PAGKRG----TDAVSEGGAMAEER
:: :: :.: :: :: :: .:::::::::::::
gi|114 -------PPTLLGPCCELPTRLFPSFCTLGRLRTLGAPTPRGWAMEADAVSEGGAMAEER
240 250 260 270 280
140 150 160 170 180 190
KIAA04 PPRLVDYFVVAGLAGNGAPIPEETWVPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PPRLVDYFVVAGLAGNGAPIPEETWVPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGY
290 300 310 320 330 340
200 210 220 230 240 250
KIAA04 TCIQASAGGHPLELSAGLLGGTQPVICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 TCIQASAGGHPLELSAGLLGGTQPVICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTT
350 360 370 380 390 400
260 270 280 290 300 310
KIAA04 PYSHSANLAPPGPGHPRTYLTYRRAAEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PYSHSANLAPPGPGHPRTYLTYRRAAEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRN
410 420 430 440 450 460
320 330 340 350 360 370
KIAA04 LNPGMWGPAVYLCYKVGLAKANTLVYEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 LNPGMWGPAVYLCYKVGLAKANTLVYEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIE
470 480 490 500 510 520
380 390 400 410 420 430
KIAA04 CWPAQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLLSAVERGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 CWPAQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLLSAVERGR
530 540 550 560 570 580
440 450 460 470 480 490
KIAA04 ALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 ALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPS
590 600 610 620 630 640
500 510 520 530 540 550
KIAA04 PQRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PQRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLV
650 660 670 680 690 700
560 570 580 590 600 610
KIAA04 HSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 HSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDP
710 720 730 740 750 760
620 630 640 650 660 670
KIAA04 PADVICVDLDTNTLFQTEEKKLLSPRTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PADVICVDLDTNTLFQTEEKKLLSPRTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASL
770 780 790 800 810 820
680 690 700 710 720 730
KIAA04 EFLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 EFLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFL
830 840 850 860 870 880
740 750 760 770 780 790
KIAA04 QGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 QGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEP
890 900 910 920 930 940
800 810 820 830 840 850
KIAA04 TPLVELEELSGSELTVFITPPEEPALPEGSESTPQYCYDGFPELRAELFESLQEQPGALP
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
gi|114 TPLVELEELSGSELTVFITPPEEPPLPEGSESTPQYCYDGFPELRAELFESLQEQPGALP
950 960 970 980 990 1000
860 870 880 890 900 910
KIAA04 VPGPSRSAPSSPAPRRTKQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 VPGPSRSAPSSPAPRRTKQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRS
1010 1020 1030 1040 1050 1060
920 930 940 950 960 970
KIAA04 APSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 APSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIV
1070 1080 1090 1100 1110 1120
980 990 1000 1010 1020 1030
KIAA04 PNTITYGYYNKAVLESKWPSGTPGGRLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PNTITYGYYNKAVLESKWPSGTPGGRLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQ
1130 1140 1150 1160 1170 1180
1040 1050 1060 1070 1080 1090
KIAA04 QQQQQEQVSAHQEAGSSQAEPYLERPSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLG
:: :::::::::::::::.::::::::::::::::::::::::::::::::::::::::
gi|114 QQ--QEQVSAHQEAGSSQADPYLERPSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLG
1190 1200 1210 1220 1230 1240
1100 1110 1120 1130 1140 1150
KIAA04 SARGAQPTVEAGVAHMIEALGVLEPRGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SARGAQPTVEAGVAHMIEALGVLEPRGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSAL
1250 1260 1270 1280 1290 1300
1160 1170 1180 1190 1200 1210
KIAA04 SAQSTEALEGLSGRGPKAGGRQDEAGTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDL
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
gi|114 SAQSTEALEGLSGRGPKAGGRQDEAGTPRRGLGARLQQLLTPSRHSPASRIPQPELPPDL
1310 1320 1330 1340 1350 1360
1220 1230 1240 1250 1260 1270
KIAA04 PPPARRSPMDSLLHPRERPGSTASESSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PPPARRSPMDSLLHPRERPGSTASESSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSF
1370 1380 1390 1400 1410 1420
1280 1290 1300 1310 1320 1330
KIAA04 QSPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 QSPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDS
1430 1440 1450 1460 1470 1480
1340 1350 1360 1370 1380 1390
KIAA04 RPSVPSPKSAGASGSKDAPVPGGPGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RPSVPSPKSAGASGSKDAPVPGGPGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWA
1490 1500 1510 1520 1530 1540
1400 1410 1420 1430 1440 1450
KIAA04 YLSPLVLRKELESLVENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 YLSPLVLRKELESLVENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASC
1550 1560 1570 1580 1590 1600
1460 1470 1480 1490 1500 1510
KIAA04 DGPSHSQAPSPWLTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 DGPSHSQAPSPWLTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVP
1610 1620 1630 1640 1650 1660
1520 1530 1540 1550 1560 1570
KIAA04 ASLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 ASLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDH
1670 1680 1690 1700 1710 1720
1580 1590 1600 1610 1620
KIAA04 VDIVAFDKKYKSAFNKLASSMGKEELRHRRAQMPTPKAIDCRKCFGAPPEC
:::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 VDIVAFDKKYKSAFNKLASSMGKEELRHRRAQMPTPKAIDCRKCFGAPPEC
1730 1740 1750 1760 1770
>>gi|158514814|sp|O75064.4|DEN4B_HUMAN RecName: Full=DEN (1496 aa)
initn: 10250 init1: 10250 opt: 10250 Z-score: 8712.0 bits: 1624.8 E(): 0
Smith-Waterman score: 10250; 100.000% identity (100.000% similar) in 1496 aa overlap (131-1626:1-1496)
110 120 130 140 150 160
KIAA04 AGPPARPPSHPPAGRPAGKRGTDAVSEGGAMAEERPPRLVDYFVVAGLAGNGAPIPEETW
::::::::::::::::::::::::::::::
gi|158 MAEERPPRLVDYFVVAGLAGNGAPIPEETW
10 20 30
170 180 190 200 210 220
KIAA04 VPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 VPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPV
40 50 60 70 80 90
230 240 250 260 270 280
KIAA04 ICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 ICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRA
100 110 120 130 140 150
290 300 310 320 330 340
KIAA04 AEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 AEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLV
160 170 180 190 200 210
350 360 370 380 390 400
KIAA04 YEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 YEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDK
220 230 240 250 260 270
410 420 430 440 450 460
KIAA04 VYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 VYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
280 290 300 310 320 330
470 480 490 500 510 520
KIAA04 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
340 350 360 370 380 390
530 540 550 560 570 580
KIAA04 LPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 LPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQ
400 410 420 430 440 450
590 600 610 620 630 640
KIAA04 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKKLLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKKLLSP
460 470 480 490 500 510
650 660 670 680 690 700
KIAA04 RTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 RTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAF
520 530 540 550 560 570
710 720 730 740 750 760
KIAA04 LRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 LRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFS
580 590 600 610 620 630
770 780 790 800 810 820
KIAA04 QFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 QFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPA
640 650 660 670 680 690
830 840 850 860 870 880
KIAA04 LPEGSESTPQYCYDGFPELRAELFESLQEQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 LPEGSESTPQYCYDGFPELRAELFESLQEQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQ
700 710 720 730 740 750
890 900 910 920 930 940
KIAA04 RMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 RMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVL
760 770 780 790 800 810
950 960 970 980 990 1000
KIAA04 PDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVPNTITYGYYNKAVLESKWPSGTPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 PDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVPNTITYGYYNKAVLESKWPSGTPGG
820 830 840 850 860 870
1010 1020 1030 1040 1050 1060
KIAA04 RLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQQQEQVSAHQEAGSSQAEPYLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 RLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQQQEQVSAHQEAGSSQAEPYLER
880 890 900 910 920 930
1070 1080 1090 1100 1110 1120
KIAA04 PSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGSARGAQPTVEAGVAHMIEALGVLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 PSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGSARGAQPTVEAGVAHMIEALGVLEP
940 950 960 970 980 990
1130 1140 1150 1160 1170 1180
KIAA04 RGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALSAQSTEALEGLSGRGPKAGGRQDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 RGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALSAQSTEALEGLSGRGPKAGGRQDEA
1000 1010 1020 1030 1040 1050
1190 1200 1210 1220 1230 1240
KIAA04 GTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDLPPPARRSPMDSLLHPRERPGSTASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 GTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDLPPPARRSPMDSLLHPRERPGSTASE
1060 1070 1080 1090 1100 1110
1250 1260 1270 1280 1290 1300
KIAA04 SSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQSPSLEILLSSCSLCRACDSLVYDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 SSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQSPSLEILLSSCSLCRACDSLVYDE
1120 1130 1140 1150 1160 1170
1310 1320 1330 1340 1350 1360
KIAA04 EIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSVPSPKSAGASGSKDAPVPGGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 EIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSVPSPKSAGASGSKDAPVPGGPG
1180 1190 1200 1210 1220 1230
1370 1380 1390 1400 1410 1420
KIAA04 PVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAYLSPLVLRKELESLVENEGSEVLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 PVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAYLSPLVLRKELESLVENEGSEVLAL
1240 1250 1260 1270 1280 1290
1430 1440 1450 1460 1470 1480
KIAA04 PELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCDGPSHSQAPSPWLTPDPASVQVRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 PELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCDGPSHSQAPSPWLTPDPASVQVRLL
1300 1310 1320 1330 1340 1350
1490 1500 1510 1520 1530 1540
KIAA04 WDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEVHKAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 WDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEVHKAVG
1360 1370 1380 1390 1400 1410
1550 1560 1570 1580 1590 1600
KIAA04 LLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 LLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEE
1420 1430 1440 1450 1460 1470
1610 1620
KIAA04 LRHRRAQMPTPKAIDCRKCFGAPPEC
::::::::::::::::::::::::::
gi|158 LRHRRAQMPTPKAIDCRKCFGAPPEC
1480 1490
>>gi|194210753|ref|XP_001493908.2| PREDICTED: DENN/MADD (1497 aa)
initn: 7935 init1: 6079 opt: 9763 Z-score: 8298.1 bits: 1548.2 E(): 0
Smith-Waterman score: 9763; 95.194% identity (98.331% similar) in 1498 aa overlap (131-1626:1-1497)
110 120 130 140 150 160
KIAA04 AGPPARPPSHPPAGRPAGKRGTDAVSEGGAMAEERPPRLVDYFVVAGLAGNGAPIPEETW
::::::::::::::.:::::::::::::::
gi|194 MAEERPPRLVDYFVIAGLAGNGAPIPEETW
10 20 30
170 180 190 200 210 220
KIAA04 VPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 VPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPV
40 50 60 70 80 90
230 240 250 260 270 280
KIAA04 ICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 ICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRA
100 110 120 130 140 150
290 300 310 320 330 340
KIAA04 AEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLV
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
gi|194 AEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAMYLCYKVGLAKANTLV
160 170 180 190 200 210
350 360 370 380 390 400
KIAA04 YEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDK
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
gi|194 YEAELLGRYPEEDNEAFPLPESVPVFCLPMGATVECWPAQTKYPVPVFSTFVLTGAAGDK
220 230 240 250 260 270
410 420 430 440 450 460
KIAA04 VYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 VYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
280 290 300 310 320 330
470 480 490 500 510 520
KIAA04 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
340 350 360 370 380 390
530 540 550 560 570 580
KIAA04 LPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQ
400 410 420 430 440 450
590 600 610 620 630 640
KIAA04 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKKLLSP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
gi|194 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKKPLSP
460 470 480 490 500 510
650 660 670 680 690 700
KIAA04 RTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 RTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAF
520 530 540 550 560 570
710 720 730 740 750 760
KIAA04 LRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFS
:::::::::::: :: ::::::::::::::::::::::::::::::::::::::.:::::
gi|194 LRFMACLLKGYRDFLLPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLRTQMFS
580 590 600 610 620 630
770 780 790 800 810 820
KIAA04 QFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPA
:::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
gi|194 QFIEECSFGSARHAALEFFDSCVDKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPP
640 650 660 670 680 690
830 840 850 860 870 880
KIAA04 LPEGSESTPQYCYDGFPELRAELFESLQEQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQ
.::::: ::::::::::::.:::::: :::::::::::::::::::::::::::::::::
gi|194 VPEGSEPTPQYCYDGFPELQAELFESPQEQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQ
700 710 720 730 740 750
890 900 910 920 930 940
KIAA04 RMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVL
::::::::::::::::::::::::::::::::::::::::.::::::.::::::: ::::
gi|194 RMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVRALHTAYQVLRQMESRKVVL
760 770 780 790 800 810
950 960 970 980 990 1000
KIAA04 PDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVPNTITYGYYNKAVLESKWPSGTPGG
:::::::::::::::::::::::.::::: .:::::::::::::::::::::::::::::
gi|194 PDEVCYRVLMQLCSHYGQPVLSVQVMLEMLRAGIVPNTITYGYYNKAVLESKWPSGTPGG
820 830 840 850 860 870
1010 1020 1030 1040 1050 1060
KIAA04 RLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQQQEQVSAHQEAGSSQAEPYLER
::::::::::::::::::::::::..:.::::::::::.: :..:.:..::::.:: :::
gi|194 RLRWAKLRNVVLGAAQFRQPLRERRKQRQQQQQQQQQQKQ-QAAAQQKTGSSQTEPSLER
880 890 900 910 920
1070 1080 1090 1100 1110 1120
KIAA04 PSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGSARGAQPTVEAGVAHMIEALGVLEP
:::::::.:::::::::::::::: ::::::::::::.::::::::::::::::::::.:
gi|194 PSPTRPLHRQTTWAGRSLRDPASPSGRLVKSGSLGSAQGAQPTVEAGVAHMIEALGVLKP
930 940 950 960 970 980
1130 1140 1150 1160 1170 1180
KIAA04 RGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALSAQSTEALEGLSGRGPKAGGRQDEA
:::::::::::::::::::::: :::::: ::::::.::.::::::::: :::.:.::::
gi|194 RGSPVPWHDGSLSDLSLTGEEPAPGGSPGDSGSALSTQSSEALEGLSGRVPKASGHQDEA
990 1000 1010 1020 1030 1040
1190 1200 1210 1220 1230 1240
KIAA04 GTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDLPPPARRSPMDSLLHPRERPGSTASE
.::::::::::::::::::.::.:::::::::::::::::::::::::.:::::::::::
gi|194 STPRRGLGARLQQLLTPSRRSPTSRIPPPELPPDLPPPARRSPMDSLLRPRERPGSTASE
1050 1060 1070 1080 1090 1100
1250 1260 1270 1280 1290 1300
KIAA04 SSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQSPSLEILLSSCSLCRACDSLVYDE
:::::::::::::::.:.::::.::::::::::::: :::::::::::::::::::::::
gi|194 SSASLGSEWDLSESSVSSLSLRHSSERLSDTPGSFQPPSLEILLSSCSLCRACDSLVYDE
1110 1120 1130 1140 1150 1160
1310 1320 1330 1340 1350
KIAA04 EIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSVPSPKSA--GASGSKDAPVPGG
:::::::::::::::::::::::::::::::::: :::.:::: : :.:.::::::::
gi|194 EIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDFRPSAPSPKPAPADAGGNKDAPVPGG
1170 1180 1190 1200 1210 1220
1360 1370 1380 1390 1400 1410
KIAA04 PGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAYLSPLVLRKELESLVENEGSEVL
::::::.:::::::::::::::::::::::::.::::::::::::::::::.::::::::
gi|194 PGPVLSNRRLCLALDEPQLCNGHMGGASRRVEGGAWAYLSPLVLRKELESLIENEGSEVL
1230 1240 1250 1260 1270 1280
1420 1430 1440 1450 1460 1470
KIAA04 ALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCDGPSHSQAPSPWLTPDPASVQVR
::::::..:::::::::::::::.:::::: ::::::::: :::::::::::::::::
gi|194 ALPELPATHPIIFWNLLWYFQRLQLPSILPCLVLASCDGPPPPQAPSPWLTPDPASVQVR
1290 1300 1310 1320 1330 1340
1480 1490 1500 1510 1520 1530
KIAA04 LLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEVHKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEVHKA
1350 1360 1370 1380 1390 1400
1540 1550 1560 1570 1580 1590
KIAA04 VGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGK
::::::::::::::::::::::::::::::::.::::.::::::::::::::::::::::
gi|194 VGLLLETLGPPPTGLHLQRGIYREILFLTMAAMGKDHMDIVAFDKKYKSAFNKLASSMGK
1410 1420 1430 1440 1450 1460
1600 1610 1620
KIAA04 EELRHRRAQMPTPKAIDCRKCFGAPPEC
::::.:::::::::::::::::::: ::
gi|194 EELRQRRAQMPTPKAIDCRKCFGAPLEC
1470 1480 1490
>>gi|194036128|ref|XP_001929547.1| PREDICTED: DENN/MADD (1493 aa)
initn: 7918 init1: 5982 opt: 9685 Z-score: 8231.8 bits: 1535.9 E(): 0
Smith-Waterman score: 9685; 94.793% identity (97.397% similar) in 1498 aa overlap (131-1626:1-1493)
110 120 130 140 150 160
KIAA04 AGPPARPPSHPPAGRPAGKRGTDAVSEGGAMAEERPPRLVDYFVVAGLAGNGAPIPEETW
::::::::::::::.:::::.:::::::::
gi|194 MAEERPPRLVDYFVIAGLAGDGAPIPEETW
10 20 30
170 180 190 200 210 220
KIAA04 VPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPV
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
gi|194 VPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASTGGHPLELSAGLLGGTQPV
40 50 60 70 80 90
230 240 250 260 270 280
KIAA04 ICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRA
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
gi|194 ICYRRGRDKPPLVELGVLSEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRA
100 110 120 130 140 150
290 300 310 320 330 340
KIAA04 AEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLV
::::::::::::::::.:::::::::::: ::::::: ::::::::::::::::::::::
gi|194 AEGAGLHALGITDLCLILPSKGEGTPHTYYRLPRNLNLGMWGPAVYLCYKVGLAKANTLV
160 170 180 190 200 210
350 360 370 380 390 400
KIAA04 YEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 YEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDK
220 230 240 250 260 270
410 420 430 440 450 460
KIAA04 VYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 VYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
280 290 300 310 320 330
470 480 490 500 510 520
KIAA04 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
340 350 360 370 380 390
530 540 550 560 570 580
KIAA04 LPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQ
::::::::::::::: :: ::.::::::::.:::::::::::::::::::::::::::::
gi|194 LPLSGASFLQLLQSLDPEQAIVLLLAVLTEQKLLVHSLRPDLLTSVCEALVSMIFPLHWQ
400 410 420 430 440 450
590 600 610 620 630 640
KIAA04 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKKLLSP
:::::::::::::::::::::::::::::::::::::::::::::::::: .:::: :::
gi|194 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFPSEEKKPLSP
460 470 480 490 500 510
650 660 670 680 690 700
KIAA04 RTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 RTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAF
520 530 540 550 560 570
710 720 730 740 750 760
KIAA04 LRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFS
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LRFMACLLKGYRDFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFS
580 590 600 610 620 630
770 780 790 800 810 820
KIAA04 QFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPA
:::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
gi|194 QFIEECSFGSARHAALEFFDSCVDKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPP
640 650 660 670 680 690
830 840 850 860 870 880
KIAA04 LPEGSESTPQYCYDGFPELRAELFESLQEQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQ
::::::::::::::::::::::::: .::::::::::::::::::::::::::::::::
gi|194 APEGSESTPQYCYDGFPELRAELFESPREQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQ
700 710 720 730 740 750
890 900 910 920 930 940
KIAA04 RMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVL
::::::::::::::::::::::::::::::::::::::::.::::::.::::::: ::::
gi|194 RMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVRALHTAYQVLRQMESRKVVL
760 770 780 790 800 810
950 960 970 980 990 1000
KIAA04 PDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVPNTITYGYYNKAVLESKWPSGTPGG
:::::::::::::::::::::::::::.::.:::::::::::::::::::::::::::::
gi|194 PDEVCYRVLMQLCSHYGQPVLSVRVMLDMRRAGIVPNTITYGYYNKAVLESKWPSGTPGG
820 830 840 850 860 870
1010 1020 1030 1040 1050 1060
KIAA04 RLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQQQEQVSAHQEAGSSQAEPYLER
:::::::::::::::::::::::: :...::.::. : .: ::::: :.:: :::
gi|194 RLRWAKLRNVVLGAAQFRQPLRERWQRRRQQKQQE-----EVDTAAQEAGSCQTEPDLER
880 890 900 910 920
1070 1080 1090 1100 1110 1120
KIAA04 PSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGSARGAQPTVEAGVAHMIEALGVLEP
:::::::::::::::::::::::: ::::::::::::::::::::::::::: :::::::
gi|194 PSPTRPLQRQTTWAGRSLRDPASPKGRLVKSGSLGSARGAQPTVEAGVAHMIGALGVLEP
930 940 950 960 970 980
1130 1140 1150 1160 1170 1180
KIAA04 RGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALSAQSTEALEGLSGRGPKAGGRQDEA
:.::.::::::::::::::::: :::::: ::::::.::::.::: ::. ::::::::::
gi|194 RASPAPWHDGSLSDLSLTGEEPAPGGSPGDSGSALSTQSTETLEGSSGQVPKAGGRQDEA
990 1000 1010 1020 1030 1040
1190 1200 1210 1220 1230 1240
KIAA04 GTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDLPPPARRSPMDSLLHPRERPGSTASE
.::::::::::::::::::.:::::.::::::::::::::::::::::::::::::::::
gi|194 STPRRGLGARLQQLLTPSRRSPASRVPPPELPPDLPPPARRSPMDSLLHPRERPGSTASE
1050 1060 1070 1080 1090 1100
1250 1260 1270 1280 1290 1300
KIAA04 SSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQSPSLEILLSSCSLCRACDSLVYDE
:::::::::::::::::..::::::::::::::::: ::::::::::::::.::::::::
gi|194 SSASLGSEWDLSESSLSSVSLRRSSERLSDTPGSFQPPSLEILLSSCSLCRTCDSLVYDE
1110 1120 1130 1140 1150 1160
1310 1320 1330 1340 1350
KIAA04 EIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSVPSPKS--AGASGSKDAPVPGG
:::::::::::::::::::::: :::::::::::::::.:::: ::::::::::::::
gi|194 EIMAGWAPDDSNLNTTCPFCACAFVPLLSVQTLDSRPSAPSPKPTPAGASGSKDAPVPGG
1170 1180 1190 1200 1210 1220
1360 1370 1380 1390 1400 1410
KIAA04 PGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAYLSPLVLRKELESLVENEGSEVL
::::::::::::::::::::::::::.:::::.:::::::::::::::::::::::::::
gi|194 PGPVLSDRRLCLALDEPQLCNGHMGGTSRRVEGGAWAYLSPLVLRKELESLVENEGSEVL
1230 1240 1250 1260 1270 1280
1420 1430 1440 1450 1460 1470
KIAA04 ALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCDGPSHSQAPSPWLTPDPASVQVR
::::::.::::::::::::::::::::::: ::::::::: : ::::::. :::::::::
gi|194 ALPELPAAHPIIFWNLLWYFQRLRLPSILPCLVLASCDGPPHPQAPSPWIMPDPASVQVR
1290 1300 1310 1320 1330 1340
1480 1490 1500 1510 1520 1530
KIAA04 LLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEVHKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEVHKA
1350 1360 1370 1380 1390 1400
1540 1550 1560 1570 1580 1590
KIAA04 VGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
gi|194 IGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMSK
1410 1420 1430 1440 1450 1460
1600 1610 1620
KIAA04 EELRHRRAQMPTPKAIDCRKCFGAPPEC
::::.:::::::::::::::::::: ::
gi|194 EELRQRRAQMPTPKAIDCRKCFGAPLEC
1470 1480 1490
>>gi|74212787|dbj|BAE33359.1| unnamed protein product [M (1510 aa)
initn: 6508 init1: 6508 opt: 9655 Z-score: 8206.2 bits: 1531.2 E(): 0
Smith-Waterman score: 9655; 93.638% identity (97.548% similar) in 1509 aa overlap (123-1626:4-1510)
100 110 120 130 140 150
KIAA04 WGRVAPPPAGPPARPPSHPPAGRPAGKRGTDAVSEGGAMAEERPPRLVDYFVVAGLAGNG
:::::. :::::::::::::::::::::::
gi|742 MEADAVSEAEAMAEERPPRLVDYFVVAGLAGNG
10 20 30
160 170 180 190 200 210
KIAA04 APIPEETWVPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAG
:::::: :::::.::::::::::::::::::::::::::::::::::.::::::::::::
gi|742 APIPEEKWVPEPTGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQTSAGGHPLELSAG
40 50 60 70 80 90
220 230 240 250 260 270
KIAA04 LLGGTQPVICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPR
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
gi|742 LLGGTQPVICYRRGRDKPPLVELGVLYEGKERPKLGFQVLDTTPYSHSANLAPPGPGHPR
100 110 120 130 140 150
280 290 300 310 320 330
KIAA04 TYLTYRRAAEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVG
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|742 TYLMYRRAAEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVG
160 170 180 190 200 210
340 350 360 370 380 390
KIAA04 LAKANTLVYEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|742 LAKANTLVYEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFV
220 230 240 250 260 270
400 410 420 430 440 450
KIAA04 LTGAAGDKVYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLS
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
gi|742 LTGAAGDKVYGAALQFYEAFPRARLSERQARALGLMSAVERGRALGGRAVRSRRAIAVLS
280 290 300 310 320 330
460 470 480 490 500 510
KIAA04 RWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|742 RWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLL
340 350 360 370 380 390
520 530 540 550 560 570
KIAA04 LCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVS
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
gi|742 LCQPVSSPLPLSGASFLQLLQNLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVS
400 410 420 430 440 450
580 590 600 610 620 630
KIAA04 MIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|742 MIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQK
460 470 480 490 500 510
640 650 660 670 680 690
KIAA04 EEKKLLSPRTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARL
:::: :: :::::::::.::::::.::::::::::::::::::::::::::::::::.::
gi|742 EEKKPLSARTLPRRPYKLLLATLTSLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRTRL
520 530 540 550 560 570
700 710 720 730 740 750
KIAA04 EREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQ
:::::::::::::::::::: ::::::::::::.:::::::.::::::::::::::::::
gi|742 EREVQGAFLRFMACLLKGYRNFLRPLTQAPSEGSRDVDNLFYLQGFLKSRERSSHKLYSQ
580 590 600 610 620 630
760 770 780 790 800 810
KIAA04 LLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPTPLVELEELSGSELTVF
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
gi|742 LLHTQMFSQFIEECSFGSARHAALEFFDSCVDKVHPEQEKPEPTPLVELEELSGSELTVF
640 650 660 670 680 690
820 830 840 850 860 870
KIAA04 ITPPEEPALPEGSESTPQYCYDGFPELRAELFESLQEQPGALPVPGPSRSAPSSPAPRRT
::::::: . :::::::::::::::::.:::::: ::: :::::::::::::::::::::
gi|742 ITPPEEPPVLEGSESTPQYCYDGFPELKAELFESPQEQQGALPVPGPSRSAPSSPAPRRT
700 710 720 730 740 750
880 890 900 910 920 930
KIAA04 KQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQ
:::::::::::::::.:::::::::::::::::::::::::::.::::.::::::::::.
gi|742 KQEMKVAQRMAQKSATVPELWARCLLGHCYGLWFLCLPAYVRSVPSRVRALHTAYHVLRE
760 770 780 790 800 810
940 950 960 970 980 990
KIAA04 MESGKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVPNTITYGYYNKAVLESK
::. ::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
gi|742 MENRKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRRAGIVPNTITYGYYNKAVLESK
820 830 840 850 860 870
1000 1010 1020 1030 1040 1050
KIAA04 WPSGTPGGRLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQQQEQVSAHQEAGSS
:::::::::::::::::::::::::::::..:.::::::::::::.: ::. .:..:::
gi|742 WPSGTPGGRLRWAKLRNVVLGAAQFRQPLKDRRQQQQQQQQQQQQKQ--QVAEQQKSGSS
880 890 900 910 920 930
1060 1070 1080 1090 1100 1110
KIAA04 QAEPYLERPSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGSARGAQPTVEAGVAHMI
:.:::::::::::::::::::::::::.:.:: ::::::::::::::.::::::::::::
gi|742 QTEPYLERPSPTRPLQRQTTWAGRSLREPSSPMGRLVKSGSLGSARGTQPTVEAGVAHMI
940 950 960 970 980 990
1120 1130 1140 1150 1160 1170
KIAA04 EALGVLEPRGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALSAQSTEALEGLSGRGPK
:::::::::::::::.::::::::::::: ::::::::::::::::::::::.:::: :
gi|742 EALGVLEPRGSPVPWQDGSLSDLSLTGEEMAPGGSPGGSGSALSAQSTEALEGISGRGSK
1000 1010 1020 1030 1040 1050
1180 1190 1200 1210 1220 1230
KIAA04 AGGRQDEAGTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDLPPPARRSPMDSLLHPRE
..: :.:.::::.::::::::::::::.. :::::::::: :::: :::::::::: :::
gi|742 TSGCQEEVGTPRKGLGARLQQLLTPSRRASASRIPPPELPSDLPPAARRSPMDSLLWPRE
1060 1070 1080 1090 1100 1110
1240 1250 1260 1270 1280 1290
KIAA04 RPGSTASESSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQSPSLEILLSSCSLCRA
::::::::::::::::::.::::::.:::::::::::::::.:: ::::::.::::::.:
gi|742 RPGSTASESSASLGSEWDISESSLSSLSLRRSSERLSDTPGAFQPPSLEILMSSCSLCHA
1120 1130 1140 1150 1160 1170
1300 1310 1320 1330 1340 1350
KIAA04 CDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSVPSPKS--AGASGS
:::::::::::::::::::::::::::::: :::::::::::::::.::::: :::::
gi|742 CDSLVYDEEIMAGWAPDDSNLNTTCPFCACHFVPLLSVQTLDSRPSAPSPKSSLAGASGC
1180 1190 1200 1210 1220 1230
1360 1370 1380 1390 1400 1410
KIAA04 KDAPVPGGPGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAYLSPLVLRKELESLV
::::.::::::::::::.:::::.:::::::::.::::::.:::::::::::::::::::
gi|742 KDAPAPGGPGPVLSDRRFCLALDQPQLCNGHMGSASRRVENGAWAYLSPLVLRKELESLV
1240 1250 1260 1270 1280 1290
1420 1430 1440 1450 1460
KIAA04 ENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCDGPSHSQ---APSPW
::::::::::::::.::::::::::::::::::::.:::::::::.:: :: .::::
gi|742 ENEGSEVLALPELPAAHPIIFWNLLWYFQRLRLPSVLPGLVLASCNGPPPSQLSQGPSPW
1300 1310 1320 1330 1340 1350
1470 1480 1490 1500 1510 1520
KIAA04 LTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVL
::::::::.:.:::::::::::::::::::::::::::::::::::::. ::::::::::
gi|742 LTPDPASVHVHLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPSCLSLALLESVL
1360 1370 1380 1390 1400 1410
1530 1540 1550 1560 1570 1580
KIAA04 RHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|742 RHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKS
1420 1430 1440 1450 1460 1470
1590 1600 1610 1620
KIAA04 AFNKLASSMGKEELRHRRAQMPTPKAIDCRKCFGAPPEC
:::::::::::::::.:::::::::::::::::::: ::
gi|742 AFNKLASSMGKEELRQRRAQMPTPKAIDCRKCFGAPLEC
1480 1490 1500 1510
>>gi|158563806|sp|Q3U1Y4.2|DEN4B_MOUSE RecName: Full=DEN (1499 aa)
initn: 6477 init1: 6477 opt: 9624 Z-score: 8179.9 bits: 1526.4 E(): 0
Smith-Waterman score: 9624; 93.738% identity (97.602% similar) in 1501 aa overlap (131-1626:1-1499)
110 120 130 140 150 160
KIAA04 AGPPARPPSHPPAGRPAGKRGTDAVSEGGAMAEERPPRLVDYFVVAGLAGNGAPIPEETW
:::::::::::::::::::::::::::: :
gi|158 MAEERPPRLVDYFVVAGLAGNGAPIPEEKW
10 20 30
170 180 190 200 210 220
KIAA04 VPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPV
::::.::::::::::::::::::::::::::::::::::.::::::::::::::::::::
gi|158 VPEPTGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQTSAGGHPLELSAGLLGGTQPV
40 50 60 70 80 90
230 240 250 260 270 280
KIAA04 ICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRA
:::::::::::::::::::::::::: :::::::::::::::::::::::::::: ::::
gi|158 ICYRRGRDKPPLVELGVLYEGKERPKLGFQVLDTTPYSHSANLAPPGPGHPRTYLMYRRA
100 110 120 130 140 150
290 300 310 320 330 340
KIAA04 AEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 AEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLV
160 170 180 190 200 210
350 360 370 380 390 400
KIAA04 YEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 YEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDK
220 230 240 250 260 270
410 420 430 440 450 460
KIAA04 VYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
gi|158 VYGAALQFYEAFPRARLSERQARALGLMSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
280 290 300 310 320 330
470 480 490 500 510 520
KIAA04 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
340 350 360 370 380 390
530 540 550 560 570 580
KIAA04 LPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQ
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|158 LPLSGASFLQLLQNLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQ
400 410 420 430 440 450
590 600 610 620 630 640
KIAA04 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKKLLSP
::::::::::::::::::::::::::::::::::::::::::::::::::: :::: ::
gi|158 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQKEEKKPLSA
460 470 480 490 500 510
650 660 670 680 690 700
KIAA04 RTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAF
:::::::::.::::::.::::::::::::::::::::::::::::::::.::::::::::
gi|158 RTLPRRPYKLLLATLTSLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRTRLEREVQGAF
520 530 540 550 560 570
710 720 730 740 750 760
KIAA04 LRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFS
:::::::::::: ::::::::::::.:::::::.::::::::::::::::::::::::::
gi|158 LRFMACLLKGYRNFLRPLTQAPSEGSRDVDNLFYLQGFLKSRERSSHKLYSQLLHTQMFS
580 590 600 610 620 630
770 780 790 800 810 820
KIAA04 QFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPA
:::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
gi|158 QFIEECSFGSARHAALEFFDSCVDKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPP
640 650 660 670 680 690
830 840 850 860 870 880
KIAA04 LPEGSESTPQYCYDGFPELRAELFESLQEQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQ
. :::::::::::::::::.:::::: ::: :::::::::::::::::::::::::::::
gi|158 VLEGSESTPQYCYDGFPELKAELFESPQEQQGALPVPGPSRSAPSSPAPRRTKQEMKVAQ
700 710 720 730 740 750
890 900 910 920 930 940
KIAA04 RMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVL
:::::::.:::::::::::::::::::::::::::.::::.::::::::::.::. ::::
gi|158 RMAQKSATVPELWARCLLGHCYGLWFLCLPAYVRSVPSRVRALHTAYHVLREMENRKVVL
760 770 780 790 800 810
950 960 970 980 990 1000
KIAA04 PDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVPNTITYGYYNKAVLESKWPSGTPGG
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
gi|158 PDEVCYRVLMQLCSHYGQPVLSVRVMLEMRRAGIVPNTITYGYYNKAVLESKWPSGTPGG
820 830 840 850 860 870
1010 1020 1030 1040 1050 1060
KIAA04 RLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQQQEQVSAHQEAGSSQAEPYLER
:::::::::::::::::::::..:.::::::::::::.: ::. .:..::::.::::::
gi|158 RLRWAKLRNVVLGAAQFRQPLKDRRQQQQQQQQQQQQKQ--QVAEQQKSGSSQTEPYLER
880 890 900 910 920
1070 1080 1090 1100 1110 1120
KIAA04 PSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGSARGAQPTVEAGVAHMIEALGVLEP
:::::::::::::::::::.:.:: ::::::::::::::.::::::::::::::::::::
gi|158 PSPTRPLQRQTTWAGRSLREPSSPMGRLVKSGSLGSARGTQPTVEAGVAHMIEALGVLEP
930 940 950 960 970 980
1130 1140 1150 1160 1170 1180
KIAA04 RGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALSAQSTEALEGLSGRGPKAGGRQDEA
:::::::.::::::::::::: ::::::::::::::::::::::.:::: :..: :.:.
gi|158 RGSPVPWQDGSLSDLSLTGEEMAPGGSPGGSGSALSAQSTEALEGISGRGSKTSGCQEEV
990 1000 1010 1020 1030 1040
1190 1200 1210 1220 1230 1240
KIAA04 GTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDLPPPARRSPMDSLLHPRERPGSTASE
::::.::::::::::::::.. :::::::::: :::: :::::::::: :::::::::::
gi|158 GTPRKGLGARLQQLLTPSRRASASRIPPPELPSDLPPAARRSPMDSLLWPRERPGSTASE
1050 1060 1070 1080 1090 1100
1250 1260 1270 1280 1290 1300
KIAA04 SSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQSPSLEILLSSCSLCRACDSLVYDE
::::::::::.::::::.:::::::::::::::.:: ::::::.::::::.:::::::::
gi|158 SSASLGSEWDISESSLSSLSLRRSSERLSDTPGAFQPPSLEILMSSCSLCHACDSLVYDE
1110 1120 1130 1140 1150 1160
1310 1320 1330 1340 1350
KIAA04 EIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSVPSPKS--AGASGSKDAPVPGG
:::::::::::::::::::::: :::::::::::::::.::::: ::::: ::::.:::
gi|158 EIMAGWAPDDSNLNTTCPFCACHFVPLLSVQTLDSRPSAPSPKSSLAGASGCKDAPAPGG
1170 1180 1190 1200 1210 1220
1360 1370 1380 1390 1400 1410
KIAA04 PGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAYLSPLVLRKELESLVENEGSEVL
:::::::::.:::::.:::::::::.::::::.:::::::::::::::::::::::::::
gi|158 PGPVLSDRRFCLALDQPQLCNGHMGSASRRVENGAWAYLSPLVLRKELESLVENEGSEVL
1230 1240 1250 1260 1270 1280
1420 1430 1440 1450 1460 1470
KIAA04 ALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCDGPSHSQ---APSPWLTPDPASV
::::::.::::::::::::::::::::.:::::::::.:: :: .::::::::::::
gi|158 ALPELPAAHPIIFWNLLWYFQRLRLPSVLPGLVLASCNGPPPSQLSQGPSPWLTPDPASV
1290 1300 1310 1320 1330 1340
1480 1490 1500 1510 1520 1530
KIAA04 QVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEV
.:.:::::::::::::::::::::::::::::::::::::. ::::::::::::::::::
gi|158 HVHLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPSCLSLALLESVLRHVGLNEV
1350 1360 1370 1380 1390 1400
1540 1550 1560 1570 1580 1590
KIAA04 HKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|158 HKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASS
1410 1420 1430 1440 1450 1460
1600 1610 1620
KIAA04 MGKEELRHRRAQMPTPKAIDCRKCFGAPPEC
:::::::.:::::::::::::::::::: ::
gi|158 MGKEELRQRRAQMPTPKAIDCRKCFGAPLEC
1470 1480 1490
>>gi|119573654|gb|EAW53269.1| hCG18235, isoform CRA_b [H (1391 aa)
initn: 8359 init1: 8359 opt: 8359 Z-score: 7105.2 bits: 1327.4 E(): 0
Smith-Waterman score: 8359; 99.919% identity (100.000% similar) in 1227 aa overlap (400-1626:165-1391)
370 380 390 400 410 420
KIAA04 MGATIECWPAQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLLS
.:::::::::::::::::::::::::::::
gi|119 PATSTLACGAQQCTCAIRWAWRRPTRWCTRQVYGAALQFYEAFPRARLSERQARALGLLS
140 150 160 170 180 190
430 440 450 460 470 480
KIAA04 AVERGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AVERGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIH
200 210 220 230 240 250
490 500 510 520 530 540
KIAA04 NVPFPSPQRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 NVPFPSPQRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLT
260 270 280 290 300 310
550 560 570 580 590 600
KIAA04 EHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSY
320 330 340 350 360 370
610 620 630 640 650 660
KIAA04 FDLHDPPADVICVDLDTNTLFQTEEKKLLSPRTLPRRPYKVLLATLTNLYQQLDQTYTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 FDLHDPPADVICVDLDTNTLFQTEEKKLLSPRTLPRRPYKVLLATLTNLYQQLDQTYTGP
380 390 400 410 420 430
670 680 690 700 710 720
KIAA04 EEEASLEFLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EEEASLEFLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDV
440 450 460 470 480 490
730 740 750 760 770 780
KIAA04 DNLFFLQGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DNLFFLQGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPE
500 510 520 530 540 550
790 800 810 820 830 840
KIAA04 QEKPEPTPLVELEELSGSELTVFITPPEEPALPEGSESTPQYCYDGFPELRAELFESLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QEKPEPTPLVELEELSGSELTVFITPPEEPALPEGSESTPQYCYDGFPELRAELFESLQE
560 570 580 590 600 610
850 860 870 880 890 900
KIAA04 QPGALPVPGPSRSAPSSPAPRRTKQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWFLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QPGALPVPGPSRSAPSSPAPRRTKQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWFLCL
620 630 640 650 660 670
910 920 930 940 950 960
KIAA04 PAYVRSAPSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PAYVRSAPSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEM
680 690 700 710 720 730
970 980 990 1000 1010 1020
KIAA04 RQAGIVPNTITYGYYNKAVLESKWPSGTPGGRLRWAKLRNVVLGAAQFRQPLRERQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 RQAGIVPNTITYGYYNKAVLESKWPSGTPGGRLRWAKLRNVVLGAAQFRQPLRERQQQQQ
740 750 760 770 780 790
1030 1040 1050 1060 1070 1080
KIAA04 QQQQQQQQQQQEQVSAHQEAGSSQAEPYLERPSPTRPLQRQTTWAGRSLRDPASPPGRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QQQQQQQQQQQEQVSAHQEAGSSQAEPYLERPSPTRPLQRQTTWAGRSLRDPASPPGRLV
800 810 820 830 840 850
1090 1100 1110 1120 1130 1140
KIAA04 KSGSLGSARGAQPTVEAGVAHMIEALGVLEPRGSPVPWHDGSLSDLSLTGEEPLPGGSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KSGSLGSARGAQPTVEAGVAHMIEALGVLEPRGSPVPWHDGSLSDLSLTGEEPLPGGSPG
860 870 880 890 900 910
1150 1160 1170 1180 1190 1200
KIAA04 GSGSALSAQSTEALEGLSGRGPKAGGRQDEAGTPRRGLGARLQQLLTPSRHSPASRIPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GSGSALSAQSTEALEGLSGRGPKAGGRQDEAGTPRRGLGARLQQLLTPSRHSPASRIPPP
920 930 940 950 960 970
1210 1220 1230 1240 1250 1260
KIAA04 ELPPDLPPPARRSPMDSLLHPRERPGSTASESSASLGSEWDLSESSLSNLSLRRSSERLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ELPPDLPPPARRSPMDSLLHPRERPGSTASESSASLGSEWDLSESSLSNLSLRRSSERLS
980 990 1000 1010 1020 1030
1270 1280 1290 1300 1310 1320
KIAA04 DTPGSFQSPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DTPGSFQSPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLLS
1040 1050 1060 1070 1080 1090
1330 1340 1350 1360 1370 1380
KIAA04 VQTLDSRPSVPSPKSAGASGSKDAPVPGGPGPVLSDRRLCLALDEPQLCNGHMGGASRRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VQTLDSRPSVPSPKSAGASGSKDAPVPGGPGPVLSDRRLCLALDEPQLCNGHMGGASRRV
1100 1110 1120 1130 1140 1150
1390 1400 1410 1420 1430 1440
KIAA04 ESGAWAYLSPLVLRKELESLVENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ESGAWAYLSPLVLRKELESLVENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPG
1160 1170 1180 1190 1200 1210
1450 1460 1470 1480 1490 1500
KIAA04 LVLASCDGPSHSQAPSPWLTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LVLASCDGPSHSQAPSPWLTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVV
1220 1230 1240 1250 1260 1270
1510 1520 1530 1540 1550 1560
KIAA04 WPGPVPASLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 WPGPVPASLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMA
1280 1290 1300 1310 1320 1330
1570 1580 1590 1600 1610 1620
KIAA04 ALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRHRRAQMPTPKAIDCRKCFGAPPEC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRHRRAQMPTPKAIDCRKCFGAPPEC
1340 1350 1360 1370 1380 1390
>>gi|55959246|emb|CAI14016.1| DENN/MADD domain containin (1384 aa)
initn: 8321 init1: 8321 opt: 8321 Z-score: 7072.9 bits: 1321.4 E(): 0
Smith-Waterman score: 8321; 100.000% identity (100.000% similar) in 1220 aa overlap (407-1626:165-1384)
380 390 400 410 420 430
KIAA04 WPAQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLLSAVERGRA
::::::::::::::::::::::::::::::
gi|559 PATSTLACGAQQCTCAIRWAWRRPTRWCTRQFYEAFPRARLSERQARALGLLSAVERGRA
140 150 160 170 180 190
440 450 460 470 480 490
KIAA04 LGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 LGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSP
200 210 220 230 240 250
500 510 520 530 540 550
KIAA04 QRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 QRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVH
260 270 280 290 300 310
560 570 580 590 600 610
KIAA04 SLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 SLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPP
320 330 340 350 360 370
620 630 640 650 660 670
KIAA04 ADVICVDLDTNTLFQTEEKKLLSPRTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 ADVICVDLDTNTLFQTEEKKLLSPRTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLE
380 390 400 410 420 430
680 690 700 710 720 730
KIAA04 FLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 FLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQ
440 450 460 470 480 490
740 750 760 770 780 790
KIAA04 GFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 GFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPT
500 510 520 530 540 550
800 810 820 830 840 850
KIAA04 PLVELEELSGSELTVFITPPEEPALPEGSESTPQYCYDGFPELRAELFESLQEQPGALPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 PLVELEELSGSELTVFITPPEEPALPEGSESTPQYCYDGFPELRAELFESLQEQPGALPV
560 570 580 590 600 610
860 870 880 890 900 910
KIAA04 PGPSRSAPSSPAPRRTKQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 PGPSRSAPSSPAPRRTKQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSA
620 630 640 650 660 670
920 930 940 950 960 970
KIAA04 PSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 PSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVP
680 690 700 710 720 730
980 990 1000 1010 1020 1030
KIAA04 NTITYGYYNKAVLESKWPSGTPGGRLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 NTITYGYYNKAVLESKWPSGTPGGRLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQ
740 750 760 770 780 790
1040 1050 1060 1070 1080 1090
KIAA04 QQQQEQVSAHQEAGSSQAEPYLERPSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 QQQQEQVSAHQEAGSSQAEPYLERPSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGS
800 810 820 830 840 850
1100 1110 1120 1130 1140 1150
KIAA04 ARGAQPTVEAGVAHMIEALGVLEPRGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 ARGAQPTVEAGVAHMIEALGVLEPRGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALS
860 870 880 890 900 910
1160 1170 1180 1190 1200 1210
KIAA04 AQSTEALEGLSGRGPKAGGRQDEAGTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 AQSTEALEGLSGRGPKAGGRQDEAGTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDLP
920 930 940 950 960 970
1220 1230 1240 1250 1260 1270
KIAA04 PPARRSPMDSLLHPRERPGSTASESSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 PPARRSPMDSLLHPRERPGSTASESSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQ
980 990 1000 1010 1020 1030
1280 1290 1300 1310 1320 1330
KIAA04 SPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 SPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSR
1040 1050 1060 1070 1080 1090
1340 1350 1360 1370 1380 1390
KIAA04 PSVPSPKSAGASGSKDAPVPGGPGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 PSVPSPKSAGASGSKDAPVPGGPGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAY
1100 1110 1120 1130 1140 1150
1400 1410 1420 1430 1440 1450
KIAA04 LSPLVLRKELESLVENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 LSPLVLRKELESLVENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCD
1160 1170 1180 1190 1200 1210
1460 1470 1480 1490 1500 1510
KIAA04 GPSHSQAPSPWLTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 GPSHSQAPSPWLTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPA
1220 1230 1240 1250 1260 1270
1520 1530 1540 1550 1560 1570
KIAA04 SLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 SLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHV
1280 1290 1300 1310 1320 1330
1580 1590 1600 1610 1620
KIAA04 DIVAFDKKYKSAFNKLASSMGKEELRHRRAQMPTPKAIDCRKCFGAPPEC
::::::::::::::::::::::::::::::::::::::::::::::::::
gi|559 DIVAFDKKYKSAFNKLASSMGKEELRHRRAQMPTPKAIDCRKCFGAPPEC
1340 1350 1360 1370 1380
>>gi|194665315|ref|XP_584938.4| PREDICTED: similar to DE (1478 aa)
initn: 7732 init1: 4302 opt: 7972 Z-score: 6776.0 bits: 1266.6 E(): 0
Smith-Waterman score: 9543; 93.658% identity (96.529% similar) in 1498 aa overlap (131-1626:1-1478)
110 120 130 140 150 160
KIAA04 AGPPARPPSHPPAGRPAGKRGTDAVSEGGAMAEERPPRLVDYFVVAGLAGNGAPIPEETW
::::::::::::::.:::::::::::::::
gi|194 MAEERPPRLVDYFVIAGLAGNGAPIPEETW
10 20 30
170 180 190 200 210 220
KIAA04 VPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPV
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 IPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPV
40 50 60 70 80 90
230 240 250 260 270 280
KIAA04 ICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 ICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRA
100 110 120 130 140 150
290 300 310 320 330 340
KIAA04 AEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 AEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLV
160 170 180 190 200 210
350 360 370 380 390 400
KIAA04 YEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDK
::::::::::::::::::::. :::::::::::::::::::::::::::
gi|194 YEAELLGRYPEEDNEAFPLPD------------IECWPAQTKYPVPVFSTFVLTGAAGDK
220 230 240 250
410 420 430 440 450 460
KIAA04 VYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 VYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
260 270 280 290 300 310
470 480 490 500 510 520
KIAA04 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
320 330 340 350 360 370
530 540 550 560 570 580
KIAA04 LPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQ
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LPLSGASFLQLLQTLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQ
380 390 400 410 420 430
590 600 610 620 630 640
KIAA04 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKKLLSP
::::::::::::::::::::::::::::::::::::.::::::::::::::::::: :::
gi|194 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPVDVICVDLDTNTLFQTEEKKPLSP
440 450 460 470 480 490
650 660 670 680 690 700
KIAA04 RTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAF
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
gi|194 RTLPRRPYKVLLATLTHLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAF
500 510 520 530 540 550
710 720 730 740 750 760
KIAA04 LRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFS
:::::::::::: ::::::::::::.::::::::::::::::::::::::::::::::::
gi|194 LRFMACLLKGYRDFLRPLTQAPSEGSRDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFS
560 570 580 590 600 610
770 780 790 800 810 820
KIAA04 QFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPA
:::::::::::::::::::::::.:::::::::::.::::::::::::::::: :::::
gi|194 QFIEECSFGSARHAALEFFDSCVDKVHPEQEKPEPVPLVELEELSGSELTVFIMPPEEPP
620 630 640 650 660 670
830 840 850 860 870 880
KIAA04 LPEGSESTPQYCYDGFPELRAELFESLQEQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQ
::::::::::::::::::::::::. ::: :::::::::::::::::::::::::::::
gi|194 APEGSESTPQYCYDGFPELRAELFEAPQEQAGALPVPGPSRSAPSSPAPRRTKQEMKVAQ
680 690 700 710 720 730
890 900 910 920 930 940
KIAA04 RMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVL
::::::::::::::::::::::::::::::::::::::::.::.:::.::::::: ::::
gi|194 RMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVRALQTAYQVLRQMESRKVVL
740 750 760 770 780 790
950 960 970 980 990 1000
KIAA04 PDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVPNTITYGYYNKAVLESKWPSGTPGG
:::::::::::::::::::::::::::.::.:::::::::::::::::::::::::::::
gi|194 PDEVCYRVLMQLCSHYGQPVLSVRVMLDMRRAGIVPNTITYGYYNKAVLESKWPSGTPGG
800 810 820 830 840 850
1010 1020 1030 1040 1050 1060
KIAA04 RLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQQQEQVSAHQEAGSSQAEPYLER
::::::::::::::::::::::: :.:.::...: .: ::::::..::::::
gi|194 RLRWAKLRNVVLGAAQFRQPLRE--------QRQRQQKREEVETAAQEAGSSKTEPYLER
860 870 880 890 900 910
1070 1080 1090 1100 1110 1120
KIAA04 PSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGSARGAQPTVEAGVAHMIEALGVLEP
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
gi|194 PSPTRPLQRQTTWAGRSLRDPASPMGRLVKSGSLGSARGAQPTVEAGVAHMIEALGVLEP
920 930 940 950 960 970
1130 1140 1150 1160 1170 1180
KIAA04 RGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALSAQSTEALEGLSGRGPKAGGRQDEA
::::.:::::::::::::::: :::::: ::::::.::::.::: ::: ::::::::::
gi|194 RGSPIPWHDGSLSDLSLTGEESAPGGSPGDSGSALSTQSTETLEGPSGRVPKAGGRQDEA
980 990 1000 1010 1020 1030
1190 1200 1210 1220 1230 1240
KIAA04 GTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDLPPPARRSPMDSLLHPRERPGSTASE
.::::::::::::::::::.::.:: :: :::::::: ::::::::::::::::::::::
gi|194 STPRRGLGARLQQLLTPSRRSPTSRAPPSELPPDLPPSARRSPMDSLLHPRERPGSTASE
1040 1050 1060 1070 1080 1090
1250 1260 1270 1280 1290 1300
KIAA04 SSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQSPSLEILLSSCSLCRACDSLVYDE
:::::::::::::::::..::::::::::::::::: :::::::::::::::::::::::
gi|194 SSASLGSEWDLSESSLSSVSLRRSSERLSDTPGSFQPPSLEILLSSCSLCRACDSLVYDE
1100 1110 1120 1130 1140 1150
1310 1320 1330 1340 1350
KIAA04 EIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSVPSPKSA--GASGSKDAPVPGG
::::::::::::::::::::::::::::::::::::::.:::: : :::::..::::::
gi|194 EIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSAPSPKPAPAGASGSSNAPVPGG
1160 1170 1180 1190 1200 1210
1360 1370 1380 1390 1400 1410
KIAA04 PGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAYLSPLVLRKELESLVENEGSEVL
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
gi|194 PGPVLSDRRLCLALDEPQLCNGHMGTASRRVESGAWAYLSPLVLRKELESLVENEGSEVL
1220 1230 1240 1250 1260 1270
1420 1430 1440 1450 1460 1470
KIAA04 ALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCDGPSHSQAPSPWLTPDPASVQVR
::::::.::::::::::::::::::::::: ::::: ::: :::.::. :::::::::
gi|194 ALPELPAAHPIIFWNLLWYFQRLRLPSILPCLVLASRDGPPPHQAPAPWIMPDPASVQVR
1280 1290 1300 1310 1320 1330
1480 1490 1500 1510 1520 1530
KIAA04 LLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEVHKA
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 LLWDVLTPDPDSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEVHKA
1340 1350 1360 1370 1380 1390
1540 1550 1560 1570 1580 1590
KIAA04 VGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGK
.::::::::::::::::::::::::::::.:::::::.::::::::::::::::::.:::
gi|194 IGLLLETLGPPPTGLHLQRGIYREILFLTLAALGKDHMDIVAFDKKYKSAFNKLASTMGK
1400 1410 1420 1430 1440 1450
1600 1610 1620
KIAA04 EELRHRRAQMPTPKAIDCRKCFGAPPEC
::::.:::::::::::::::::::: ::
gi|194 EELRQRRAQMPTPKAIDCRKCFGAPLEC
1460 1470
>>gi|148683202|gb|EDL15149.1| DENN/MADD domain containin (1419 aa)
initn: 4831 init1: 3875 opt: 7643 Z-score: 6496.6 bits: 1214.8 E(): 0
Smith-Waterman score: 8771; 87.343% identity (91.252% similar) in 1509 aa overlap (131-1626:1-1419)
110 120 130 140 150 160
KIAA04 AGPPARPPSHPPAGRPAGKRGTDAVSEGGAMAEERPPRLVDYFVVAGLAGNGAPIPEETW
:::::::::::::::::::::::::::: :
gi|148 MAEERPPRLVDYFVVAGLAGNGAPIPEEKW
10 20 30
170 180 190 200 210 220
KIAA04 VPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPV
::::.::::::::::::::::::::::::::::::::::.::::::::::::::::::::
gi|148 VPEPTGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQTSAGGHPLELSAGLLGGTQPV
40 50 60 70 80 90
230 240 250 260 270 280
KIAA04 ICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRA
:::::::::::::::::::::::::: :::::::::::::::::::::::::::: ::::
gi|148 ICYRRGRDKPPLVELGVLYEGKERPKLGFQVLDTTPYSHSANLAPPGPGHPRTYLMYRRA
100 110 120 130 140 150
290 300 310 320 330 340
KIAA04 AEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLV
::::::::::::::::::::::::::::::::::::::::
gi|148 AEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGM--------------------
160 170 180 190
350 360 370 380 390 400
KIAA04 YEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDK
gi|148 ------------------------------------------------------------
410 420 430 440 450 460
KIAA04 VYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
gi|148 VYGAALQFYEAFPRARLSERQARALGLMSAVERGRALGGRAVRSRRAIAVLSRWPAFPAF
200 210 220 230 240 250
470 480 490 500 510 520
KIAA04 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 RAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSP
260 270 280 290 300 310
530 540 550 560 570 580
KIAA04 LPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQ
:::::::::::::.::::::::::::::::::::::::::::::::::::::
gi|148 LPLSGASFLQLLQNLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVS--------
320 330 340 350 360
590 600 610 620 630 640
KIAA04 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKKLLSP
::::::::::::::::::::::::::::::::::::::::::::::::::: :::: ::
gi|148 CPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQKEEKKPLSA
370 380 390 400 410 420
650 660 670 680 690
KIAA04 RTLPRRPYKVLLATLTNLYQQLDQT--------YTGPEEEASLEFLLTDYEAVCGRRARL
:::::::::.::::::.:::::::. ::::::::::::::::::::::::.::
gi|148 RTLPRRPYKLLLATLTSLYQQLDQSEKLVGLGAYTGPEEEASLEFLLTDYEAVCGRRTRL
430 440 450 460 470 480
700 710 720 730 740 750
KIAA04 EREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQ
:::::::::::::::::::: ::::::::::::.:::::::.::::::::::::::::::
gi|148 EREVQGAFLRFMACLLKGYRNFLRPLTQAPSEGSRDVDNLFYLQGFLKSRERSSHKLYSQ
490 500 510 520 530 540
760 770 780 790 800 810
KIAA04 LLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPTPLVELEELSGSELTVF
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
gi|148 LLHTQMFSQFIEECSFGSARHAALEFFDSCVDKVHPEQEKPEPTPLVELEELSGSELTVF
550 560 570 580 590 600
820 830 840 850 860 870
KIAA04 ITPPEEPALPEGSESTPQYCYDGFPELRAELFESLQEQPGALPVPGPSRSAPSSPAPRRT
::::::: . :::::::::::::::::.:::::: ::: :::::::::::::::::::::
gi|148 ITPPEEPPVLEGSESTPQYCYDGFPELKAELFESPQEQQGALPVPGPSRSAPSSPAPRRT
610 620 630 640 650 660
880 890 900 910 920 930
KIAA04 KQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQ
:::::::::::::::.:::::::::::::::::::::::::::.::::.::::::::::.
gi|148 KQEMKVAQRMAQKSATVPELWARCLLGHCYGLWFLCLPAYVRSVPSRVRALHTAYHVLRE
670 680 690 700 710 720
940 950 960 970 980 990
KIAA04 MESGKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVPNTITYGYYNKAVLESK
::. ::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
gi|148 MENRKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRRAGIVPNTITYGYYNKAVLESK
730 740 750 760 770 780
1000 1010 1020 1030 1040 1050
KIAA04 WPSGTPGGRLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQQQEQVSAHQEAGSS
:::::::::::::::::::::::::::::..:.::::::::::::.: ::. .:..:::
gi|148 WPSGTPGGRLRWAKLRNVVLGAAQFRQPLKDRRQQQQQQQQQQQQKQ--QVAEQQKSGSS
790 800 810 820 830 840
1060 1070 1080 1090 1100 1110
KIAA04 QAEPYLERPSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGSARGAQPTVEAGVAHMI
:.:::::::::::::::::::::::::.:.:: ::::::::::::::.::::::::::::
gi|148 QTEPYLERPSPTRPLQRQTTWAGRSLREPSSPMGRLVKSGSLGSARGTQPTVEAGVAHMI
850 860 870 880 890 900
1120 1130 1140 1150 1160 1170
KIAA04 EALGVLEPRGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALSAQSTEALEGLSGRGPK
:::::::::::::::.::::::::::::: ::::::::::::::::::::::.:::: :
gi|148 EALGVLEPRGSPVPWQDGSLSDLSLTGEEMAPGGSPGGSGSALSAQSTEALEGISGRGSK
910 920 930 940 950 960
1180 1190 1200 1210 1220 1230
KIAA04 AGGRQDEAGTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDLPPPARRSPMDSLLHPRE
..: :.:.::::.::::::::::::::.. :::::::::: :::: :::::::::: :::
gi|148 TSGCQEEVGTPRKGLGARLQQLLTPSRRASASRIPPPELPSDLPPAARRSPMDSLLWPRE
970 980 990 1000 1010 1020
1240 1250 1260 1270 1280 1290
KIAA04 RPGSTASESSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQSPSLEILLSSCSLCRA
::::::::::::::::::.::::::.:::::::::::::::.:: ::::::.::::::.:
gi|148 RPGSTASESSASLGSEWDISESSLSSLSLRRSSERLSDTPGAFQPPSLEILMSSCSLCHA
1030 1040 1050 1060 1070 1080
1300 1310 1320 1330 1340 1350
KIAA04 CDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSVPSPKS--AGASGS
:::::::::::::::::::::::::::::: :::::::::::::::.::::: :::::
gi|148 CDSLVYDEEIMAGWAPDDSNLNTTCPFCACHFVPLLSVQTLDSRPSAPSPKSSLAGASGC
1090 1100 1110 1120 1130 1140
1360 1370 1380 1390 1400 1410
KIAA04 KDAPVPGGPGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAYLSPLVLRKELESLV
::::.::::::::::::.:::::.:::::::::.::::::.:::::::::::::::::::
gi|148 KDAPAPGGPGPVLSDRRFCLALDQPQLCNGHMGSASRRVENGAWAYLSPLVLRKELESLV
1150 1160 1170 1180 1190 1200
1420 1430 1440 1450 1460
KIAA04 ENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCDGPSHSQ---APSPW
::::::::::::::.::::::::::::::::::::.:::::::::.:: :: .::::
gi|148 ENEGSEVLALPELPAAHPIIFWNLLWYFQRLRLPSVLPGLVLASCNGPPPSQLSQGPSPW
1210 1220 1230 1240 1250 1260
1470 1480 1490 1500 1510 1520
KIAA04 LTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVL
::::::::.:.:::::::::::::::::::::::::::::::::::::. ::::::::::
gi|148 LTPDPASVHVHLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPSCLSLALLESVL
1270 1280 1290 1300 1310 1320
1530 1540 1550 1560 1570 1580
KIAA04 RHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 RHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKS
1330 1340 1350 1360 1370 1380
1590 1600 1610 1620
KIAA04 AFNKLASSMGKEELRHRRAQMPTPKAIDCRKCFGAPPEC
:::::::::::::::.:::::::::::::::::::: ::
gi|148 AFNKLASSMGKEELRQRRAQMPTPKAIDCRKCFGAPLEC
1390 1400 1410
1626 residues in 1 query sequences
2693465022 residues in 7827732 library sequences
Tcomplib [34.26] (8 proc)
start: Wed Mar 4 23:51:12 2009 done: Wed Mar 4 23:55:53 2009
Total Scan time: 2118.980 Total Display time: 1.830
Function used was FASTA [version 34.26.5 April 26, 2007]