# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/fj12051.fasta.nr -Q ../query/KIAA0474.ptfa /cdna2/lib/nr/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
KIAA0474, 782 aa
vs /cdna2/lib/nr/nr library
2693465022 residues in 7827732 sequences
statistics sampled from 60000 to 7825064 sequences
Expectation_n fit: rho(ln(x))= 5.5846+/-0.000188; mu= 11.5676+/- 0.011
mean_var=83.0893+/-15.880, 0's: 35 Z-trim: 43 B-trim: 23 in 1/65
Lambda= 0.140702
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 38, opt: 26, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7827732)
gi|108998965|ref|XP_001109771.1| PREDICTED: RAP1, (1242) 4660 956.2 0
gi|109475701|ref|XP_233609.4| PREDICTED: similar t ( 753) 4618 947.6 0
gi|168273006|dbj|BAG10342.1| Rap1 GTPase-activatin ( 681) 4537 931.1 0
gi|119615385|gb|EAW94979.1| RAP1, GTPase activatin ( 689) 4511 925.8 0
gi|55729452|emb|CAH91457.1| hypothetical protein [ ( 804) 3698 760.8 0
gi|119615387|gb|EAW94981.1| RAP1, GTPase activatin ( 727) 3669 754.9 2.5e-215
gi|124487211|ref|NP_001074624.1| Rap1 GTPase-activ ( 727) 3524 725.5 1.8e-206
gi|123229439|emb|CAM19420.1| Rap1 GTPase-activatin ( 729) 3519 724.5 3.7e-206
gi|149024348|gb|EDL80845.1| RAP1, GTPase activatin ( 727) 3518 724.3 4.2e-206
gi|119615389|gb|EAW94983.1| RAP1, GTPase activatin ( 617) 3380 696.2 1e-197
gi|119615390|gb|EAW94984.1| RAP1, GTPase activatin ( 694) 3377 695.6 1.7e-197
gi|71296783|gb|AAH35030.1| RAP1GAP protein [Homo s ( 692) 3362 692.6 1.4e-196
gi|55959690|emb|CAI16255.1| RAP1 GTPase activating ( 693) 3358 691.8 2.4e-196
gi|149024349|gb|EDL80846.1| RAP1, GTPase activatin ( 693) 3343 688.7 2e-195
gi|215273877|sp|P47736.2|RPGP1_HUMAN RecName: Full ( 663) 3336 687.3 5.2e-195
gi|123229440|emb|CAM19421.1| Rap1 GTPase-activatin ( 694) 3336 687.3 5.4e-195
gi|190856|gb|AAA60252.1| GTPase activating protein ( 663) 3331 686.3 1.1e-194
gi|32452014|gb|AAH54490.1| RAP1 GTPase activating ( 663) 3329 685.9 1.4e-194
gi|115304761|gb|AAI23396.1| RAP1 GTPase activating ( 663) 3298 679.6 1.1e-192
gi|55731989|emb|CAH92703.1| hypothetical protein [ ( 625) 3294 678.7 1.8e-192
gi|30354392|gb|AAH52065.1| Rap1gap protein [Mus mu ( 656) 3232 666.2 1.2e-188
gi|169642403|gb|AAI60660.1| Zgc:175180 protein [Da ( 695) 3213 662.3 1.8e-187
gi|148697964|gb|EDL29911.1| mCG120453, isoform CRA ( 489) 2991 617.2 4.9e-174
gi|148697965|gb|EDL29912.1| mCG120453, isoform CRA ( 458) 2950 608.8 1.5e-171
gi|149517546|ref|XP_001517102.1| PREDICTED: simila ( 499) 2918 602.3 1.5e-169
gi|123229442|emb|CAM19423.1| Rap1 GTPase-activatin ( 405) 2483 514.0 4.7e-143
gi|73950650|ref|XP_855199.1| PREDICTED: similar to ( 450) 2482 513.8 5.9e-143
gi|49259129|pdb|1SRQ|A Chain A, Crystal Structure ( 341) 2282 473.1 7.9e-131
gi|169791851|pdb|3BRW|A Chain A, Structure Of The ( 341) 2274 471.5 2.4e-130
gi|5650776|gb|AAD45946.1|AF151966_1 GTPase activat ( 556) 2268 470.4 8.3e-130
gi|53126175|emb|CAG30935.1| hypothetical protein [ ( 751) 1983 412.7 2.7e-112
gi|162416276|sp|Q5ZMV8.2|RPGP2_CHICK RecName: Full ( 730) 1976 411.2 7.1e-112
gi|47220760|emb|CAG11829.1| unnamed protein produc ( 467) 1856 386.7 1.1e-104
gi|73967387|ref|XP_548324.2| PREDICTED: similar to ( 916) 1842 384.1 1.3e-103
gi|162416269|sp|Q684P5.2|RPGP2_HUMAN RecName: Full ( 730) 1838 383.2 1.9e-103
gi|51869677|emb|CAF31652.1| Rap1 GTPase activating ( 730) 1832 382.0 4.5e-103
gi|119610934|gb|EAW90528.1| GTPase activating Rap/ ( 675) 1811 377.7 8.1e-102
gi|34530484|dbj|BAC85912.1| unnamed protein produc ( 711) 1808 377.1 1.3e-101
gi|81862523|sp|Q5SVL6.1|RPGP2_MOUSE RecName: Full= ( 712) 1794 374.3 9.3e-101
gi|47204365|emb|CAG14305.1| unnamed protein produc ( 314) 1778 370.8 4.6e-100
gi|50949940|emb|CAH10514.1| hypothetical protein [ ( 715) 1777 370.8 1e-99
gi|156086740|ref|NP_001093868.1| GTPase activating ( 715) 1777 370.8 1e-99
gi|51869679|emb|CAF31653.1| Rap1 GTPase activating ( 715) 1771 369.6 2.4e-99
gi|210084902|gb|EEA33401.1| hypothetical protein B ( 784) 1762 367.8 9e-99
gi|55959693|emb|CAI16258.1| RAP1 GTPase activating ( 268) 1735 362.0 1.7e-97
gi|194217443|ref|XP_001502535.2| PREDICTED: simila ( 775) 1689 353.0 2.6e-94
gi|21410877|gb|AAH30891.1| Rap1gap protein [Mus mu ( 423) 1672 349.4 1.8e-93
gi|149637553|ref|XP_001510893.1| PREDICTED: hypoth (1134) 1672 349.7 3.8e-93
gi|126631803|gb|AAI33819.1| Zgc:153898 protein [Da ( 472) 1664 347.8 5.9e-93
gi|189534018|ref|XP_001920828.1| PREDICTED: simila ( 707) 1650 345.1 5.8e-92
>>gi|108998965|ref|XP_001109771.1| PREDICTED: RAP1, GTPa (1242 aa)
initn: 4647 init1: 4647 opt: 4660 Z-score: 5105.9 bits: 956.2 E(): 0
Smith-Waterman score: 4896; 93.932% identity (95.575% similar) in 791 aa overlap (2-780:120-910)
10 20
KIAA04 RAPECR---AQDAPGPGPWVNTSANRGHPPS
.: : ... : ::::::::::::
gi|108 KLPGASRSVGSTSSPAAPLCTHPPGYQGSLSPGCSFAAPEESDLPTLLVNTSANRGHPPS
90 100 110 120 130 140
30 40 50 60 70 80
KIAA04 DPHSEEADPSSNSDIATEQPYNFWVDKSFTSRRSVWRSDGQNQHFPQALDLSRVNLVPSY
:: ::::::::: :::::::::::::::: ::::::::::::.::::::::::::::::
gi|108 GPHLEEADPSSNSGIATEQPYNFWVDKSFTPRRSVWRSDGQNQRFPQALDLSRVNLVPSY
150 160 170 180 190 200
90 100 110 120 130 140
KIAA04 TPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|108 TPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLIL
210 220 230 240 250 260
150 160 170 180 190 200
KIAA04 LPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
gi|108 LPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDT
270 280 290 300 310 320
210 220 230 240 250 260
KIAA04 ALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|108 ALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVD
330 340 350 360 370 380
270 280 290 300 310 320
KIAA04 RFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|108 RFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFL
390 400 410 420 430 440
330 340 350 360 370 380
KIAA04 GQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|108 GQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRH
450 460 470 480 490 500
390 400 410 420 430 440
KIAA04 IGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|108 IGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGP
510 520 530 540 550 560
450 460 470 480 490 500
KIAA04 PLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|108 PLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQS
570 580 590 600 610 620
510 520 530 540 550 560
KIAA04 MMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|108 MMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNN
630 640 650 660 670 680
570 580 590 600 610 620
KIAA04 PDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|108 PDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAI
690 700 710 720 730 740
630 640 650 660 670 680
KIAA04 GIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
gi|108 GIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETATQRAEA
750 760 770 780 790 800
690 700 710 720 730
KIAA04 LKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKR---------DSFIYSTW
::::::::::::::::::::::::::::::: :.. :. :.. .:
gi|108 LKDFSRSSSSASSFASVVEETEGVDGEDTGLVRGSGGRGLHRSLEGGSLLPGDALSRTTS
810 820 830 840 850 860
740 750 760 770 780
KIAA04 LEDSVSTTSGGSSPDAGKLGDPACPEIKIQLEASEQHMPQLGC
: :::::::::::::::::::::::::::::::::::::::
gi|108 LGDSVSTTSGGSSPDAGKLGDPACPEIKIQLEASEQHMPQLMRPQKHKGKVPCQAQADGT
870 880 890 900 910 920
gi|108 SALKTNTSLAEPSRPGIGEAAGIIPTPSLGVRAGAGIAQWKQDWGPGLGPPRASITPEHP
930 940 950 960 970 980
>>gi|109475701|ref|XP_233609.4| PREDICTED: similar to Ra (753 aa)
initn: 4470 init1: 4470 opt: 4618 Z-score: 5062.9 bits: 947.6 E(): 0
Smith-Waterman score: 4618; 93.631% identity (97.290% similar) in 738 aa overlap (53-782:16-753)
30 40 50 60 70 80
KIAA04 RGHPPSDPHSEEADPSSNSDIATEQPYNFWVDKSFTSRRSVWRSDGQNQHFPQALDLSRV
:::::. :.::::::::.. :::.:.. :
gi|109 MSGRKRSFTFGAYGGVDKSFSPRQSVWRSDGQKHSFPQTLNVLLV
10 20 30 40
90 100 110 120 130 140
KIAA04 NLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
. :::. : ::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 DSVPSHPASPYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
50 60 70 80 90 100
150 160 170 180 190 200
KIAA04 PFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
gi|109 PFPLILLPQFGGYWIEGTNHEISSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
110 120 130 140 150 160
210 220 230 240 250 260
KIAA04 YYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVC
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 YYSLDTALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVC
170 180 190 200 210 220
270 280 290 300 310 320
KIAA04 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
230 240 250 260 270 280
330 340 350 360 370 380
KIAA04 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
290 300 310 320 330 340
390 400 410 420 430 440
KIAA04 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
350 360 370 380 390 400
450 460 470 480 490 500
KIAA04 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
410 420 430 440 450 460
510 520 530 540 550 560
KIAA04 HIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|109 HIHSQSMMGLGGDDDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
470 480 490 500 510 520
570 580 590 600 610 620
KIAA04 SFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGS
::.::::::::::::::::::::::::::::::.:::.::::::::::::::::::::::
gi|109 SFTPNNPDLAKAAGISLLIPGKSASRFGRRGSALGIGAVEESLIVPGKSPTRKKSGPFGS
530 540 550 560 570 580
630 640 650 660 670 680
KIAA04 RRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:
gi|109 RRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRVESA
590 600 610 620 630 640
690 700 710 720 730 740
KIAA04 AQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLED
:::.:.:. :::::::::::.:::::::::::.:::.:::::::::::::::.:::::.:
gi|109 AQRTEVLQGFSRSSSSASSFTSVVEETEGVDGDDTGMESVSSSGTPHKRDSFLYSTWLDD
650 660 670 680 690 700
750 760 770 780
KIAA04 SVSTTSGGSSP--------DAGKLGDPACPEIKIQLEASEQHMPQLGC
::::::::::: :: : :::::::::::::.:::: ::.::
gi|109 SVSTTSGGSSPGLTRSPHPDAVKSGDPACPEIKIQLETSEQHTPQMGC
710 720 730 740 750
>>gi|168273006|dbj|BAG10342.1| Rap1 GTPase-activating pr (681 aa)
initn: 4537 init1: 4537 opt: 4537 Z-score: 4974.7 bits: 931.1 E(): 0
Smith-Waterman score: 4537; 100.000% identity (100.000% similar) in 681 aa overlap (102-782:1-681)
80 90 100 110 120 130
KIAA04 HFPQALDLSRVNLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPY
::::::::::::::::::::::::::::::
gi|168 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPY
10 20 30
140 150 160 170 180 190
KIAA04 PSVHEVLGREGPFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 PSVHEVLGREGPFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIY
40 50 60 70 80 90
200 210 220 230 240 250
KIAA04 RKHFLGKEHFNYYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 RKHFLGKEHFNYYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEF
100 110 120 130 140 150
260 270 280 290 300 310
KIAA04 PNVVQMAKLVCEDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 PNVVQMAKLVCEDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEEL
160 170 180 190 200 210
320 330 340 350 360 370
KIAA04 FSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 FSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVST
220 230 240 250 260 270
380 390 400 410 420 430
KIAA04 KLPYTEGDAQQLQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 KLPYTEGDAQQLQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGP
280 290 300 310 320 330
440 450 460 470 480 490
KIAA04 LYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 LYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTR
340 350 360 370 380 390
500 510 520 530 540 550
KIAA04 AALLETLYEELHIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 AALLETLYEELHIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNK
400 410 420 430 440 450
560 570 580 590 600 610
KIAA04 KPNTVSTSHSGSFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 KPNTVSTSHSGSFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKS
460 470 480 490 500 510
620 630 640 650 660 670
KIAA04 PTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 PTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPE
520 530 540 550 560 570
680 690 700 710 720 730
KIAA04 MPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 MPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKR
580 590 600 610 620 630
740 750 760 770 780
KIAA04 DSFIYSTWLEDSVSTTSGGSSPDAGKLGDPACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::::::::::::::::::::::::::::::::
gi|168 DSFIYSTWLEDSVSTTSGGSSPDAGKLGDPACPEIKIQLEASEQHMPQLGC
640 650 660 670 680
>>gi|119615385|gb|EAW94979.1| RAP1, GTPase activating pr (689 aa)
initn: 4370 init1: 4329 opt: 4511 Z-score: 4946.1 bits: 925.8 E(): 0
Smith-Waterman score: 4511; 98.839% identity (98.839% similar) in 689 aa overlap (102-782:1-689)
80 90 100 110 120 130
KIAA04 HFPQALDLSRVNLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPY
::::::::::::::::::::::::::::::
gi|119 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPY
10 20 30
140 150 160 170 180 190
KIAA04 PSVHEVLGREGPFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PSVHEVLGREGPFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIY
40 50 60 70 80 90
200 210 220 230 240 250
KIAA04 RKHFLGKEHFNYYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 RKHFLGKEHFNYYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEF
100 110 120 130 140 150
260 270 280 290 300 310
KIAA04 PNVVQMAKLVCEDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PNVVQMAKLVCEDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEEL
160 170 180 190 200 210
320 330 340 350 360 370
KIAA04 FSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 FSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVST
220 230 240 250 260 270
380 390 400 410 420 430
KIAA04 KLPYTEGDAQQLQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KLPYTEGDAQQLQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGP
280 290 300 310 320 330
440 450 460 470 480 490
KIAA04 LYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTR
340 350 360 370 380 390
500 510 520 530 540 550
KIAA04 AALLETLYEELHIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AALLETLYEELHIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNK
400 410 420 430 440 450
560 570 580 590 600 610
KIAA04 KPNTVSTSHSGSFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KPNTVSTSHSGSFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKS
460 470 480 490 500 510
620 630 640 650 660 670
KIAA04 PTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPE
520 530 540 550 560 570
680 690 700 710 720 730
KIAA04 MPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 MPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKR
580 590 600 610 620 630
740 750 760 770 780
KIAA04 DSFIYSTWLEDSVSTTSGGSSP--------DAGKLGDPACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::: :::::::::::::::::::::::::::::
gi|119 DSFIYSTWLEDSVSTTSGGSSPGPSRSPHPDAGKLGDPACPEIKIQLEASEQHMPQLGC
640 650 660 670 680
>>gi|55729452|emb|CAH91457.1| hypothetical protein [Pong (804 aa)
initn: 3722 init1: 3695 opt: 3698 Z-score: 4053.2 bits: 760.8 E(): 0
Smith-Waterman score: 3698; 93.355% identity (95.349% similar) in 602 aa overlap (53-653:16-609)
30 40 50 60 70 80
KIAA04 RGHPPSDPHSEEADPSSNSDIATEQPYNFWVDKSFTSRRSVWRSDGQNQHFPQALDLSRV
::::::::::::::::::::::::::::::
gi|557 MSGRKRSFTFGAYGGVDKSFTSRRSVWRSDGQNQHFPQALDLSRV
10 20 30 40
90 100 110 120 130 140
KIAA04 NLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|557 NLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
50 60 70 80 90 100
150 160 170 180 190 200
KIAA04 PFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
gi|557 PFPLILLPQFGGYWIEGTNREITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
110 120 130 140 150 160
210 220 230 240 250 260
KIAA04 YYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVC
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|557 YYSLDTALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVC
170 180 190 200 210 220
270 280 290 300 310 320
KIAA04 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|557 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
230 240 250 260 270 280
330 340 350 360 370 380
KIAA04 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|557 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
290 300 310 320 330 340
390 400 410 420 430 440
KIAA04 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|557 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
350 360 370 380 390 400
450 460 470 480 490 500
KIAA04 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|557 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
410 420 430 440 450 460
510 520 530 540 550 560
KIAA04 HIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|557 HIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
470 480 490 500 510 520
570 580 590 600 610 620
KIAA04 SFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGS
::::::::::::::::::::::::::::::::::::::::: ..: : . . . :
gi|557 SFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEE-VVVRGAAGSGGCLHALFS
530 540 550 560 570 580
630 640 650 660 670 680
KIAA04 RRSSAIGIENIQEVQEKRESP-PAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAET
::. : .: .: .: : :: .:
gi|557 ARSQDGG--HIGDV-----APLPPGQAPGRAGWSGGSSDGTQHLLWGLVPVPEPVPLTRG
590 600 610 620 630
690 700 710 720 730 740
KIAA04 AAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLE
gi|557 FWPCLGPPGPWPSPCQDPVPKGPTPSRTSPNIAGLHGAPSLSSALTPPPRHELTWGPTPS
640 650 660 670 680 690
>>gi|119615387|gb|EAW94981.1| RAP1, GTPase activating pr (727 aa)
initn: 4539 init1: 3598 opt: 3669 Z-score: 4022.0 bits: 754.9 E(): 2.5e-215
Smith-Waterman score: 4620; 95.393% identity (95.393% similar) in 738 aa overlap (53-782:16-727)
30 40 50 60 70 80
KIAA04 RGHPPSDPHSEEADPSSNSDIATEQPYNFWVDKSFTSRRSVWRSDGQNQHFPQALDLSRV
::::::::::::::::::::::::::::::
gi|119 MSGRKRSFTFGAYGGVDKSFTSRRSVWRSDGQNQHFPQALDLSRV
10 20 30 40
90 100 110 120 130 140
KIAA04 NLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 NLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
50 60 70 80 90 100
150 160 170 180 190 200
KIAA04 PFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
110 120 130 140 150 160
210 220 230 240 250 260
KIAA04 YYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 YYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVC
170 180 190 200 210 220
270 280 290 300 310 320
KIAA04 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
230 240 250 260 270 280
330 340 350 360 370 380
KIAA04 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
290 300 310 320 330 340
390 400 410 420 430 440
KIAA04 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
350 360 370 380 390 400
450 460 470 480 490 500
KIAA04 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
410 420 430 440 450 460
510 520 530 540 550 560
KIAA04 HIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 HIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
470 480 490 500 510 520
570 580 590 600 610 620
KIAA04 SFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGS
::::::::::::::::: :::::::::::::::::
gi|119 SFAPNNPDLAKAAGISL--------------------------IVPGKSPTRKKSGPFGS
530 540 550
630 640 650 660 670 680
KIAA04 RRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 RRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETA
560 570 580 590 600 610
690 700 710 720 730 740
KIAA04 AQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLED
620 630 640 650 660 670
750 760 770 780
KIAA04 SVSTTSGGSSP--------DAGKLGDPACPEIKIQLEASEQHMPQLGC
::::::::::: :::::::::::::::::::::::::::::
gi|119 SVSTTSGGSSPGPSRSPHPDAGKLGDPACPEIKIQLEASEQHMPQLGC
680 690 700 710 720
>>gi|124487211|ref|NP_001074624.1| Rap1 GTPase-activatin (727 aa)
initn: 3645 init1: 3468 opt: 3524 Z-score: 3863.0 bits: 725.5 E(): 1.8e-206
Smith-Waterman score: 4415; 90.650% identity (93.902% similar) in 738 aa overlap (53-782:16-727)
30 40 50 60 70 80
KIAA04 RGHPPSDPHSEEADPSSNSDIATEQPYNFWVDKSFTSRRSVWRSDGQNQHFPQALDLSRV
:::::. :.::::::::.: :::::.: :
gi|124 MSGRKRSFTFGAYGGVDKSFSLRQSVWRSDGQKQSFPQALNLLLV
10 20 30 40
90 100 110 120 130 140
KIAA04 NLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
. :::. : ::::::::::::::::::::::::::::::::::::::::::::::::::
gi|124 DSVPSHPASPYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
50 60 70 80 90 100
150 160 170 180 190 200
KIAA04 PFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
::::::::::::::::::::::.:.:::::::::::::::::::::::::::::::::::
gi|124 PFPLILLPQFGGYWIEGTNHEISSLPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
110 120 130 140 150 160
210 220 230 240 250 260
KIAA04 YYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVC
:::::.::::::::::::::::::::::::::::::.:::::::::::::::::::::::
gi|124 YYSLDTALGHLVFSLKYDVIGDQEHLRLLLRTKCRTHHDVIPISCLTEFPNVVQMAKLVC
170 180 190 200 210 220
270 280 290 300 310 320
KIAA04 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|124 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
230 240 250 260 270 280
330 340 350 360 370 380
KIAA04 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|124 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
290 300 310 320 330 340
390 400 410 420 430 440
KIAA04 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|124 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
350 360 370 380 390 400
450 460 470 480 490 500
KIAA04 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|124 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
410 420 430 440 450 460
510 520 530 540 550 560
KIAA04 HIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|124 HIHSQSMMGLGGDDDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
470 480 490 500 510 520
570 580 590 600 610 620
KIAA04 SFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGS
::.:::::::::::::: :::::::::::::::::
gi|124 SFTPNNPDLAKAAGISL--------------------------IVPGKSPTRKKSGPFGS
530 540 550
630 640 650 660 670 680
KIAA04 RRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:
gi|124 RRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRVESA
560 570 580 590 600 610
690 700 710 720 730 740
KIAA04 AQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLED
:::.:.:. :::::::::::.:::::::::::.:::::::::::::::::::.:::::.:
gi|124 AQRTEVLQGFSRSSSSASSFTSVVEETEGVDGDDTGLESVSSSGTPHKRDSFLYSTWLDD
620 630 640 650 660 670
750 760 770 780
KIAA04 SVSTTSGGSSP--------DAGKLGDPACPEIKIQLEASEQHMPQLGC
::::::::::: :.:: :::::::::::::.:::: ::.::
gi|124 SVSTTSGGSSPGLTRSPHPDVGKSGDPACPEIKIQLETSEQHTPQMGC
680 690 700 710 720
>>gi|123229439|emb|CAM19420.1| Rap1 GTPase-activating pr (729 aa)
initn: 3468 init1: 3468 opt: 3519 Z-score: 3857.5 bits: 724.5 E(): 3.7e-206
Smith-Waterman score: 4055; 90.574% identity (94.109% similar) in 679 aa overlap (53-731:16-668)
30 40 50 60 70 80
KIAA04 RGHPPSDPHSEEADPSSNSDIATEQPYNFWVDKSFTSRRSVWRSDGQNQHFPQALDLSRV
:::::. :.::::::::.: :::::.: :
gi|123 MSGRKRSFTFGAYGGVDKSFSLRQSVWRSDGQKQSFPQALNLLLV
10 20 30 40
90 100 110 120 130 140
KIAA04 NLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
. :::. : ::::::::::::::::::::::::::::::::::::::::::::::::::
gi|123 DSVPSHPASPYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
50 60 70 80 90 100
150 160 170 180 190 200
KIAA04 PFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
::::::::::::::::::::::.:.:::::::::::::::::::::::::::::::::::
gi|123 PFPLILLPQFGGYWIEGTNHEISSLPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
110 120 130 140 150 160
210 220 230 240 250 260
KIAA04 YYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVC
:::::.::::::::::::::::::::::::::::::.:::::::::::::::::::::::
gi|123 YYSLDTALGHLVFSLKYDVIGDQEHLRLLLRTKCRTHHDVIPISCLTEFPNVVQMAKLVC
170 180 190 200 210 220
270 280 290 300 310 320
KIAA04 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|123 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
230 240 250 260 270 280
330 340 350 360 370 380
KIAA04 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|123 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
290 300 310 320 330 340
390 400 410 420 430 440
KIAA04 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|123 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
350 360 370 380 390 400
450 460 470 480 490 500
KIAA04 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|123 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
410 420 430 440 450 460
510 520 530 540 550 560
KIAA04 HIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|123 HIHSQSMMGLGGDDDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
470 480 490 500 510 520
570 580 590 600 610 620
KIAA04 SFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGS
::.:::::::::::: :::::::::::::::::::
gi|123 SFTPNNPDLAKAAGI--------------------------SLIVPGKSPTRKKSGPFGS
530 540 550
630 640 650 660 670 680
KIAA04 RRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:
gi|123 RRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRVESA
560 570 580 590 600 610
690 700 710 720 730 740
KIAA04 AQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLED
:::.:.:. :::::::::::.:::::::::::.::::. .. . :.:
gi|123 AQRTEVLQGFSRSSSSASSFTSVVEETEGVDGDDTGLHMAGRQREHHERGQLPSEVAPSC
620 630 640 650 660 670
750 760 770 780
KIAA04 SVSTTSGGSSPDAGKLGDPACPEIKIQLEASEQHMPQLGC
gi|123 PPSQASHGHPTQTSASRGTLRVPRSRSNWKHLSSTHPRWAASCHLISRRD
680 690 700 710 720
>>gi|149024348|gb|EDL80845.1| RAP1, GTPase activating pr (727 aa)
initn: 3634 init1: 3464 opt: 3518 Z-score: 3856.4 bits: 724.3 E(): 4.2e-206
Smith-Waterman score: 4402; 90.379% identity (93.767% similar) in 738 aa overlap (53-782:16-727)
30 40 50 60 70 80
KIAA04 RGHPPSDPHSEEADPSSNSDIATEQPYNFWVDKSFTSRRSVWRSDGQNQHFPQALDLSRV
:::::. :.::::::::.. :::.:.. :
gi|149 MSGRKRSFTFGAYGGVDKSFSPRQSVWRSDGQKHSFPQTLNVLLV
10 20 30 40
90 100 110 120 130 140
KIAA04 NLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
. :::. : ::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 DSVPSHPASPYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREG
50 60 70 80 90 100
150 160 170 180 190 200
KIAA04 PFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
gi|149 PFPLILLPQFGGYWIEGTNHEISSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFN
110 120 130 140 150 160
210 220 230 240 250 260
KIAA04 YYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVC
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 YYSLDTALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVC
170 180 190 200 210 220
270 280 290 300 310 320
KIAA04 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 EDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFV
230 240 250 260 270 280
330 340 350 360 370 380
KIAA04 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 EFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQ
290 300 310 320 330 340
390 400 410 420 430 440
KIAA04 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDD
350 360 370 380 390 400
450 460 470 480 490 500
KIAA04 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 VPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL
410 420 430 440 450 460
510 520 530 540 550 560
KIAA04 HIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|149 HIHSQSMMGLGGDDDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSG
470 480 490 500 510 520
570 580 590 600 610 620
KIAA04 SFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGS
::.:::::::::::::: :::::::::::::::::
gi|149 SFTPNNPDLAKAAGISL--------------------------IVPGKSPTRKKSGPFGS
530 540 550
630 640 650 660 670 680
KIAA04 RRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:
gi|149 RRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRVESA
560 570 580 590 600 610
690 700 710 720 730 740
KIAA04 AQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLED
:::.:.:. :::::::::::.:::::::::::.:::.:::::::::::::::.:::::.:
gi|149 AQRTEVLQGFSRSSSSASSFTSVVEETEGVDGDDTGMESVSSSGTPHKRDSFLYSTWLDD
620 630 640 650 660 670
750 760 770 780
KIAA04 SVSTTSGGSSP--------DAGKLGDPACPEIKIQLEASEQHMPQLGC
::::::::::: :: : :::::::::::::.:::: ::.::
gi|149 SVSTTSGGSSPGLTRSPHPDAVKSGDPACPEIKIQLETSEQHTPQMGC
680 690 700 710 720
>>gi|119615389|gb|EAW94983.1| RAP1, GTPase activating pr (617 aa)
initn: 3377 init1: 3377 opt: 3380 Z-score: 3706.0 bits: 696.2 E(): 1e-197
Smith-Waterman score: 3380; 93.128% identity (94.937% similar) in 553 aa overlap (102-653:1-545)
80 90 100 110 120 130
KIAA04 HFPQALDLSRVNLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPY
::::::::::::::::::::::::::::::
gi|119 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPY
10 20 30
140 150 160 170 180 190
KIAA04 PSVHEVLGREGPFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PSVHEVLGREGPFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIY
40 50 60 70 80 90
200 210 220 230 240 250
KIAA04 RKHFLGKEHFNYYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 RKHFLGKEHFNYYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEF
100 110 120 130 140 150
260 270 280 290 300 310
KIAA04 PNVVQMAKLVCEDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PNVVQMAKLVCEDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEEL
160 170 180 190 200 210
320 330 340 350 360 370
KIAA04 FSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 FSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVST
220 230 240 250 260 270
380 390 400 410 420 430
KIAA04 KLPYTEGDAQQLQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KLPYTEGDAQQLQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGP
280 290 300 310 320 330
440 450 460 470 480 490
KIAA04 LYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTR
340 350 360 370 380 390
500 510 520 530 540 550
KIAA04 AALLETLYEELHIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 AALLETLYEELHIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNK
400 410 420 430 440 450
560 570 580 590 600 610
KIAA04 KPNTVSTSHSGSFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKS
:::::::::::::::::::::::::::::::::::::::::::::::::::: ..: : .
gi|119 KPNTVSTSHSGSFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEE-VVVRGAA
460 470 480 490 500
620 630 640 650 660 670
KIAA04 PTRKKSGPFGSRRSSAIGIENIQEVQEKRESP-PAGQKTPDSGHVSQEPKSENSSTQSSP
. . : ::. : .: .: .: : :: .:
gi|119 GSGGCLHALFSARSQDGG--HIGDV-----APLPPGQAPGRAGWSGGSSDGTQHLLWGLV
510 520 530 540 550 560
680 690 700 710 720 730
KIAA04 EMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHK
gi|119 PVPEPVPLTRGFWPCLGPWDPGPVPARIRYPKALHPAARPPISPVCMERHPSPLP
570 580 590 600 610
782 residues in 1 query sequences
2693465022 residues in 7827732 library sequences
Tcomplib [34.26] (8 proc)
start: Wed Mar 4 23:43:15 2009 done: Wed Mar 4 23:46:47 2009
Total Scan time: 1582.820 Total Display time: 0.420
Function used was FASTA [version 34.26.5 April 26, 2007]