hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-04012917/chunk_1/iprscan-20080502-04012917.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0472 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00069.15.fs Protein kinase domain 133.4 8.6e-38 1 PF00069.15.ls Protein kinase domain 132.3 1.2e-36 1 PF07714.7.fs Protein tyrosine kinase 79.7 4.8e-23 3 PF07714.7.ls Protein tyrosine kinase 79.2 1.2e-20 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00069.15.fs 1/1 88 333 .. 1 276 [. 133.4 8.6e-38 PF00069.15.ls 1/1 88 345 .. 1 287 [] 132.3 1.2e-36 PF07714.7.fs 1/3 89 151 .. 1 72 [. 16.6 0.0001 PF07714.7.ls 1/1 89 342 .. 1 272 [] 79.2 1.2e-20 PF07714.7.fs 2/3 182 233 .. 107 158 .. 41.6 5.6e-12 PF07714.7.fs 3/3 252 342 .. 183 272 .] 21.6 3.5e-06 Alignments of top-scoring domains: PF00069.15.fs: domain 1 of 1, from 88 to 333: score 133.4, E = 8.6e-38 *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr +l++ lG+G +G+Vy++ + g A+K + ++ek++ d ++ KIAA0472 88 PKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLAL-- 132 lsEiqilkrL.sHpNIvrlidvfed.......kdhlylVlEycegGLrvl E +++++L++H+ v l++++ d + +++++ + l++E + + KIAA0472 133 --EFHYMRSLpKHERLVDLHGSVIDynygggsSIAVLLIMERL-HR---- 175 dLfdylsetrrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeN dL++ l+ +l + ++ ial +++g+ +LHs+g +HRD+K+ N KIAA0472 176 DLYTGLK-----AGL--TLETRLQIALDVVEGIRFLHSQGLVHRDIKLKN 218 ILldnngvvdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllgg +Lld+++ Ki+D G++ + ++vGTp mAPE+ + KIAA0472 219 VLLDKQNRA----KITDLGFC----KpEAMmSGSIVGTPIHMAPEL--FT 258 ngygtkvDvWSlGvilyelltGk....pPFsgevqds.ldqlqlirkilg +y+ +vDv+++G+++++ ++G + + F + + d+l+ ++++ KIAA0472 259 GKYDNSVDVYAFGILFWYICSGSvklpEAFERC---AsKDHLWNNVRRGA 305 pplefdspewdsisrsefrrlpnlseeakdLikkcLnkDPskRl<-* +p + + + +ee+ +L++ c++ DP kR+ KIAA0472 306 RPERLPVF----------------DEECWQLMEACWDGDPLKRP 333 PF00069.15.ls: domain 1 of 1, from 88 to 345: score 132.3, E = 1.2e-36 *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr +l++ lG+G +G+Vy++ + g A+K + ++ek++ d ++ KIAA0472 88 PKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLAL-- 132 lsEiqilkrL.sHpNIvrlidvfed.......kdhlylVlEycegGLrvl E +++++L++H+ v l++++ d + +++++ + l++E + + KIAA0472 133 --EFHYMRSLpKHERLVDLHGSVIDynygggsSIAVLLIMERL-HR---- 175 dLfdylsetrrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeN dL++ l+ +l + ++ ial +++g+ +LHs+g +HRD+K+ N KIAA0472 176 DLYTGLK-----AGL--TLETRLQIALDVVEGIRFLHSQGLVHRDIKLKN 218 ILldnngvvdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllgg +Lld+++ Ki+D G++ + ++vGTp mAPE+ + KIAA0472 219 VLLDKQNRA----KITDLGFC----KpEAMmSGSIVGTPIHMAPEL--FT 258 ngygtkvDvWSlGvilyelltGk....pPFsgevqds.ldqlqlirkilg +y+ +vDv+++G+++++ ++G + + F + + d+l+ ++++ KIAA0472 259 GKYDNSVDVYAFGILFWYICSGSvklpEAFERC---AsKDHLWNNVRRGA 305 pplefdspewdsisrsefrrlpnlseeakdLikkcLnkDPskRlt...ae +p + + + +ee+ +L++ c++ DP kR+ + + KIAA0472 306 RPERLPVF----------------DEECWQLMEACWDGDPLKRPLlgiVQ 339 eilqHPwf<-* lq + KIAA0472 340 PMLQG--I 345 PF07714.7.fs: domain 1 of 3, from 89 to 151: score 16.6, E = 0.0001 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie klg++LG+G++G+Vy++ g++ ++A K++ + +e++ KIAA0472 89 -KLGQELGRGQYGVVYLCDNW----GGHFPCALKSV--VPPDEKH-- 126 redFlrEAsiMkklGdHpNiVrLlG<-* + d+ E M++l++H+ +V L+G KIAA0472 127 WNDLALEFHYMRSLPKHERLVDLHG 151 PF07714.7.ls: domain 1 of 1, from 89 to 342: score 79.2, E = 1.2e-20 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie klg++LG+G++G+Vy++ g++ ++A K++ + +e++ KIAA0472 89 -KLGQELGRGQYGVVYLCDNW----GGHFPCALKSV--VPPDEKH-- 126 redFlrEAsiMkklGdHpNiVrLlGvct.......kegePggpglyiVtE + d+ E M++l++H+ +V L+G +++ + +++ + +++++E KIAA0472 127 WNDLALEFHYMRSLPKHERLVDLHGSVIdynygggS-SIA----VLLIME 171 ymegGdLldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLA + dL++ L++ Ltl++ l++al++ +G +L+s+++vHRD+ KIAA0472 172 RLHR-DLYTGLKAG-----LTLETRLQIALDVVEGIRFLHSQGLVHRDIK 215 ARNcLVsenlvVKIsDFGLaRdiynddyYvrkkgggk..lPvkWmAPEsl +N+L+++++ +KI+D G ++ + +g+ + P+ mAPE l KIAA0472 216 LKNVLLDKQNRAKITDLGFCKPE-------AMMSGSIvgTPIH-MAPE-L 256 kygkFtskSDVWSFGVlLWEiftlGe.qP..FYpgm.sneevlellyedG ++gk+ DV++FG+l W i++ + P+ F + + s + + + ++G KIAA0472 257 FTGKYDNSVDVYAFGILFWYICSGSVkLPeaF-ERCaSKDHLWNNV-RRG 304 yRLprPenCPdelYdlMlqCWaedPedRPtFselveeL<-* R +r + +e +lM CW+ dP +RP ++ L KIAA0472 305 ARPERLPVFDEECWQLMEACWDGDPLKRPLLGIVQPML 342 PF07714.7.fs: domain 2 of 3, from 182 to 233: score 41.6, E = 5.6e-12 *->grpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLVsenlvVK + Ltl++ l++al++ +G +L+s+++vHRD+ +N+L+++++ +K KIAA0472 182 KAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAK 228 IsDFG<-* I+D G KIAA0472 229 ITDLG 233 PF07714.7.fs: domain 3 of 3, from 252 to 342: score 21.6, E = 3.5e-06 *->mAPEslkygkFtskSDVWSFGVlLWEiftlGe.qP..FYpgm.snee mAPE l++gk+ DV++FG+l W i++ + P+ F + + s KIAA0472 252 MAPE-LFTGKYDNSVDVYAFGILFWYICSGSVkLPeaF-ERCaSKDH 296 vlellyedGyRLprPenCPdelYdlMlqCWaedPedRPtFselveeL<-* + + + ++G R +r + +e +lM CW+ dP +RP ++ L KIAA0472 297 LWNNV-RRGARPERLPVFDEECWQLMEACWDGDPLKRPLLGIVQPML 342 //