hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-02322694/chunk_1/iprscan-20080502-02322694.nocrc
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Query sequence: KIAA0421
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N 
--------       -----------                              -----    ------- ---
PF00454.17.ls  Phosphatidylinositol 3- and 4-kinase     225.8      9e-65   1
PF00454.17.fs  Phosphatidylinositol 3- and 4-kinase     224.0    3.1e-64   1
PF02260.10.fs  FATC domain                               44.5    5.9e-12   1
PF02260.10.ls  FATC domain                               46.4    8.7e-11   1
PF02985.12.ls  HEAT repeat                               21.5     0.0029   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
PF02985.12.ls    1/1     144   179 ..     1    36 []    21.5   0.0029
PF00454.17.fs    1/1     476   754 ..     1   329 []   224.0  3.1e-64
PF00454.17.ls    1/1     476   754 ..     1   329 []   225.8    9e-65
PF02260.10.fs    1/1    1956  1988 .]     1    33 []    44.5  5.9e-12
PF02260.10.ls    1/1    1956  1988 .]     1    33 []    46.4  8.7e-11

Alignments of top-scoring domains:
PF02985.12.ls: domain 1 of 1, from 144 to 179: score 21.5, E = 0.0029
                   *->e.ildellplllkllnDpdpeVReaAaeaLgalaevl<-*
                      ++++  ++p l++ ln+p+  VR++ ++ L+++a+     
    KIAA0421   144    ApWR-GIIPQLFSRLNHPEVYVRQSICNLLCRVAQDS    179  

PF00454.17.fs: domain 1 of 1, from 476 to 754: score 224.0, E = 3.1e-64
                   *->gypfifKgGdDLrsrQDelvlQligVfKPkDEEPyApnNPkgtkvsq
                       yp++fKg +DL+   De+++Q++                     + 
    KIAA0421   476    SYPYLFKGLEDLH--LDERIMQFL-------------------SIVN 501  

                   GerlmnkllkgegldrrRnlqltaYlviplgpgsGlIEwvpnsttlaeil
                     +++ ++ ++e   +     +++Y+v plg++sGlI+wv+ +t+l ++ 
    KIAA0421   502 --TMFATINRQETPRFH----ARHYSVTPLGTRSGLIQWVDGATPLFGLY 545  

                   rtymvkkaikdfnksrffkdk.kttk.klek.nakll.k.e...hk.llq
                   + +  +++++ + +++ +++ ++   + + +++    +k ++  +   l+
    KIAA0421   546 KRWQ-QREAALQAQKAQDSYQtPQNPgIVPRpSELYYsKiGpalKTvGLS 594  

                   mvldrkqltllekvevFeeklsntpkpgllqwFvkknpdaapyeewfeRf
                    + +r  ++l  ++ v ee ++ tp++ l ++++++ +++   +ew++  
    KIAA0421   595 LDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTP---DEWWR-- 639  

                   ardnfvrScAgmsvldYiLGigDRHldNiLvkkndkktGklfHIDFGlcf
                   + + ++rS A+ms+++Yi+G+gDRHldN L+   d++tG+++HID++ cf
    KIAA0421   640 VTQSYARSTAVMSMVGYIIGLGDRHLDNVLI---DMTTGEVVHIDYNVCF 686  

                   ghvkgkrgpkpervPFrLTrWPQaklpmveamggyiasLgpsgdeglFre
                   +  kgk + +pe+vPFr T+      ++  a+       g++g eg Fr 
    KIAA0421   687 E--KGKSLRVPEKVPFRMTQ------NIETAL-------GVTGVEGVFRL 721  

                   lceeayralRrnanlllnlLkkkAvarGelmledglpdwrs<-*
                   +ce+++ ++Rr  + ll+lL        e++++d+l+dw+    
    KIAA0421   722 SCEQVLHIMRRGRETLLTLL--------EAFVYDPLVDWTA    754  

PF00454.17.ls: domain 1 of 1, from 476 to 754: score 225.8, E = 9e-65
                   *->gypfifKgGdDLrsrQDelvlQligVfKPkDEEPyApnNPkgtkvsq
                       yp++fKg +DL+   De+++Q++                     + 
    KIAA0421   476    SYPYLFKGLEDLH--LDERIMQFL-------------------SIVN 501  

                   GerlmnkllkgegldrrRnlqltaYlviplgpgsGlIEwvpnsttlaeil
                     +++ ++ ++e   +     +++Y+v plg++sGlI+wv+ +t+l ++ 
    KIAA0421   502 --TMFATINRQETPRFH----ARHYSVTPLGTRSGLIQWVDGATPLFGLY 545  

                   rtymvkkaikdfnksrffkdk.kttk.klek.nakll.k.e...hk.llq
                   + +  +++++ + +++ +++ ++   + + +++    +k ++  +   l+
    KIAA0421   546 KRWQ-QREAALQAQKAQDSYQtPQNPgIVPRpSELYYsKiGpalKTvGLS 594  

                   mvldrkqltllekvevFeeklsntpkpgllqwFvkknpdaapyeewfeRf
                    + +r  ++l  ++ v ee ++ tp++ l ++++++ +++   +ew++  
    KIAA0421   595 LDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTP---DEWWR-- 639  

                   ardnfvrScAgmsvldYiLGigDRHldNiLvkkndkktGklfHIDFGlcf
                   + + ++rS A+ms+++Yi+G+gDRHldN L+   d++tG+++HID++ cf
    KIAA0421   640 VTQSYARSTAVMSMVGYIIGLGDRHLDNVLI---DMTTGEVVHIDYNVCF 686  

                   ghvkgkrgpkpervPFrLTrWPQaklpmveamggyiasLgpsgdeglFre
                   +  kgk + +pe+vPFr T+      ++  a+       g++g eg Fr 
    KIAA0421   687 E--KGKSLRVPEKVPFRMTQ------NIETAL-------GVTGVEGVFRL 721  

                   lceeayralRrnanlllnlLkkkAvarGelmledglpdwrs<-*
                   +ce+++ ++Rr  + ll+lL        e++++d+l+dw+    
    KIAA0421   722 SCEQVLHIMRRGRETLLTLL--------EAFVYDPLVDWTA    754  

PF02260.10.fs: domain 1 of 1, from 1956 to 1988: score 44.5, E = 5.9e-12
                   *->epLsvegqvedLIqqATspenLsqmYiGWcPfl<-*
                        +sv +qv++ I++AT+ +nL+q+Y+GW++++   
    KIAA0421  1956    RRMSVAEQVDYVIKEATNLDNLAQLYEGWTAWV    1988 

PF02260.10.ls: domain 1 of 1, from 1956 to 1988: score 46.4, E = 8.7e-11
                   *->epLsvegqvedLIqqATspenLsqmYiGWcPfl<-*
                        +sv +qv++ I++AT+ +nL+q+Y+GW++++   
    KIAA0421  1956    RRMSVAEQVDYVIKEATNLDNLAQLYEGWTAWV    1988 

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