# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/hh00327.fasta.huge -Q ../query/KIAA0374.ptfa ./tmplib.23147 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 KIAA0374, 584 aa
 vs ./tmplib.23147 library

1986921 residues in  2037 sequences
  Expectation_n fit: rho(ln(x))= 9.3920+/-0.00838; mu= -4.0469+/- 0.567
 mean_var=308.4847+/-73.341, 0's: 0 Z-trim: 2  B-trim: 8 in 1/39
 Lambda= 0.073023

FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 37, opt: 25, open/ext: -10/-2, width:  16
The best scores are:                                      opt bits E(2037)
KIAA1472  ( 601 res)   fj03211                     ( 601)  870 105.0 1.8e-23


>>KIAA1472  ( 601 res)   fj03211                          (601 aa)
 initn: 1157 init1: 808 opt: 870  Z-score: 513.4  bits: 105.0 E(): 1.8e-23
Smith-Waterman score: 1171;  41.835% identity (64.771% similar) in 545 aa overlap (50-568:96-598)

      20        30        40        50        60             70    
KIAA03 FNSLVEAAVVCQALAPGVSCRRVRREAMPGSGPSERMTWPGPALSA-----GPPTRP---
                                     :.:  .:.  :   :.     ::  :    
KIAA14 SSRYKKESKSGLVKPGSEADFSSSSSTGSISAPEVHMSTAGSKRSSSSRNRGPHGRSNGA
          70        80        90       100       110       120     

              80        90       100       110       120       130 
KIAA03 LSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSRRRTSPPVSVRDAYGTSSLSSSSNSG
        :  ::  :  :  : ..:..:            : . :: :... .:. ::  ::::::
KIAA14 SSHKPGSSPSSP--REKDLLSML----------CRNQLSP-VNIHPSYAPSS-PSSSNSG
         130         140                 150        160        170 

             140       150       160       170       180       190 
KIAA03 SYKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQ
       :::::: ::  ::: .:  :..:::..::.::::::::::::: .::::..::... ::.
KIAA14 SYKGSDCSPIMRRSGRYMSCGENHGVRPPNPEQYLTPLQQKEVTVRHLKTKLKESERRLH
             180       190       200       210       220       230 

             200       210       220       230       240       250 
KIAA03 DRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDK
       .:..:: .::.::.::.:::::::::::::::::::::::::::::::.:....: ::::
KIAA14 ERESEIVELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDK
             240       250       260       270       280       290 

             260       270       280       290       300       310 
KIAA03 GLQKYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDP
       :.:::::::::::::::.::.:::.:..:  ...   .    :: .::: .     ..: 
KIAA14 GIQKYFVDINIQNKKLESLLQSMEMAHSGSLRDELCLDFPCDSPEKSLTLNPPLDTMADG
             300       310       320       330       340       350 

             320       330       340       350       360       370 
KIAA03 AVCGDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSF
           ..  :.        :::  . ..:.  . :: ..   . .. .. :  :  .::. 
KIAA14 LSLEEQVTGE--------GADRELLVGDSIANSTDLFDEI-VTATTTESGDLEL-VHST-
             360               370       380        390        400 

             380         390       400       410       420         
KIAA03 GLGPRFPASNTYEKL--LCGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQA--QV
             :..:. : :  . :.: :   : . :::.::: : :.: .. ....: :   . 
KIAA14 ------PGANVLELLPIVMGQEEG---SVVVERAVQTDVVPYSPAISELIQSVLQKLQDP
                    410          420       430       440       450 

       430               440          450       460       470      
KIAA03 CGT--------DPESGDRCPE-LDAHPSG--PRDPNSAVVVTVGDELEAPEPITRGPTPQ
       : .        .:.: .  :: :.:      ::.::::....    .:.:     . .  
KIAA14 CPSSLASPDESEPDSMESFPESLSALVVDLTPRNPNSAILLS---PVETP----YANVDA
             460       470       480       490              500    

        480       490       500          510       520       530   
KIAA03 RPGANPNPGQSVSVVCPMEEEEEAAVAEKEP---KSYWSRHYIVDLLAVVVPAVPTVAWL
       .  ::    .   ..: .::. ....   .    ..:::  ..::::::..:.:::: : 
KIAA14 EVHANRLMRELDFAAC-VEERLDGVIPLARGGVVRQYWSSSFLVDLLAVAAPVVPTVLWA
          510       520        530       540       550       560   

           540       550       560       570       580    
KIAA03 CRSQRRQGQPIYNISSLLRGCCTVALHSIRRISCRSLSQPSPSPAGGGSQL
         .::   .:.:::..::::::.:::::.:: . :                
KIAA14 FSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFRIKT             
           570       580       590       600              




584 residues in 1 query   sequences
1986921 residues in 2037 library sequences
 Scomplib [34.26]
 start: Thu Dec 18 15:18:55 2008 done: Thu Dec 18 15:18:55 2008
 Total Scan time:  0.500 Total Display time:  0.010

Function used was FASTA [version 34.26.5 April 26, 2007]