hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080501/iprscan-20080501-21384504/chunk_1/iprscan-20080501-21384504.nocrc
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Query sequence: KIAA0253
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model     Description                                   Score    E-value  N 
--------  -----------                                   -----    ------- ---
PF05450.5.ls Nicastrin                                     452.7   4.5e-133   1
PF05450.5.fs Nicastrin                                     450.9   1.6e-132   1

Parsed for domains:
Model     Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------  ------- ----- -----    ----- -----      -----  -------
PF05450.5.fs   1/1     273   498 ..     1   260 []   450.9 1.6e-132
PF05450.5.ls   1/1     273   498 ..     1   260 []   452.7 4.5e-133

Alignments of top-scoring domains:
PF05450.5.fs: domain 1 of 1, from 273 to 498: score 450.9, E = 1.6e-132
                   *->kvvlVtaRlDstsmFddvslGAdSsvsgfvvlLaAAdaLGTQIskll
                      +vv++++RlDs+s+F++v++GA+S+v++fv++LaAA+aL     k+ 
    KIAA0253   273    RVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEAL----QKA- 314  

                   pdiSnlkrNVlFvfFnGEsyDYIGSqRfvYdlenGkFPQmIRSdrThvkP
                   pd+++l rNV+FvfF+GE++DYIGS+R+vYd+e+GkFP            
    KIAA0253   315 PDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFP------------ 352  

                   IsldnIDlvLEiGqvgkatsrginlfylHvDPmaarnqsvktqvldlLak
                   + l+n D+++E+Gqv+++ts+    +++H+DP++++n+sv +qv+dlLa+
    KIAA0253   353 VQLENVDSFVELGQVALRTSLE---LWMHTDPVSQKNESVRNQVEDLLAT 399  

                   iekSlasgnekvlpastsnpglPPsSlqSFLRanpnfsaVvLadfdteFe
                   +ekS+a+++ ++l++  +++ lPPsSlq+FLRa+ n+s+VvLad+++ F+
    KIAA0253   400 LEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRAR-NISGVVLADHSGAFH 448  

                   NrfYhSIyDdaeNinstYanwskKYDFTQLedldLGdeeDLnekdslqms
                   N++Y+SIyD+aeNin+ Y++w +             +eeDLn++++++++
    KIAA0253   449 NKYYQSIYDTAENINVSYPEWLS-------------PEEDLNFVTDTAKA 485  

                   vvnaAslvAraLY<-*
                   ++ +A++++raLY   
    KIAA0253   486 LADVATVLGRALY    498  

PF05450.5.ls: domain 1 of 1, from 273 to 498: score 452.7, E = 4.5e-133
                   *->kvvlVtaRlDstsmFddvslGAdSsvsgfvvlLaAAdaLGTQIskll
                      +vv++++RlDs+s+F++v++GA+S+v++fv++LaAA+aL     k+ 
    KIAA0253   273    RVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEAL----QKA- 314  

                   pdiSnlkrNVlFvfFnGEsyDYIGSqRfvYdlenGkFPQmIRSdrThvkP
                   pd+++l rNV+FvfF+GE++DYIGS+R+vYd+e+GkFP            
    KIAA0253   315 PDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFP------------ 352  

                   IsldnIDlvLEiGqvgkatsrginlfylHvDPmaarnqsvktqvldlLak
                   + l+n D+++E+Gqv+++ts+    +++H+DP++++n+sv +qv+dlLa+
    KIAA0253   353 VQLENVDSFVELGQVALRTSLE---LWMHTDPVSQKNESVRNQVEDLLAT 399  

                   iekSlasgnekvlpastsnpglPPsSlqSFLRanpnfsaVvLadfdteFe
                   +ekS+a+++ ++l++  +++ lPPsSlq+FLRa+ n+s+VvLad+++ F+
    KIAA0253   400 LEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRAR-NISGVVLADHSGAFH 448  

                   NrfYhSIyDdaeNinstYanwskKYDFTQLedldLGdeeDLnekdslqms
                   N++Y+SIyD+aeNin+ Y++w +             +eeDLn++++++++
    KIAA0253   449 NKYYQSIYDTAENINVSYPEWLS-------------PEEDLNFVTDTAKA 485  

                   vvnaAslvAraLY<-*
                   ++ +A++++raLY   
    KIAA0253   486 LADVATVLGRALY    498  

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