hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-20140782/chunk_1/iprscan-20080501-20140782.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0204 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00069.15.ls Protein kinase domain 316.7 3.8e-92 1 PF00069.15.fs Protein kinase domain 314.8 1.4e-91 1 PF07714.7.fs Protein tyrosine kinase 107.0 5.9e-31 1 PF07714.7.ls Protein tyrosine kinase 106.3 8.5e-29 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00069.15.fs 1/1 46 304 .. 1 287 [] 314.8 1.4e-91 PF07714.7.fs 1/1 46 292 .. 1 262 [. 107.0 5.9e-31 PF00069.15.ls 1/1 46 304 .. 1 287 [] 316.7 3.8e-92 PF07714.7.ls 1/1 46 304 .. 1 272 [] 106.3 8.5e-29 Alignments of top-scoring domains: PF00069.15.fs: domain 1 of 1, from 46 to 304: score 314.8, E = 1.4e-91 *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr +e+++ lG G+fG+Vyka++k t+ + A K+i+ ++e++ +d+ KIAA0204 46 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMV-- 90 lsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdylse Ei il++++HpNIv+l+d+f+++++l++ E+c gG +++ KIAA0204 91 --EIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGG----AVDAVML- 133 trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnngv + ++pl +e +++ +++Q+l +l+YLH+n+iiHRDLK NIL+ +g+ KIAA0204 134 -ELERPL--TESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGD 180 vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvll....ggngyg + K+aDFG+++k t+ ++ ++f GTp++mAPEv++ +++++++y+ KIAA0204 181 I----KLADFGVSAKN-TrTIQrRDSFIGTPYWMAPEVVMcetsKDRPYD 225 tkvDvWSlGvilyelltGkpPFsgevqds.ldqlqlirkilgpplefdsp +k+DvWSlG++l+e++ +pP + ++ + l +i+k +p l +s KIAA0204 226 YKADVWSLGITLIEMAEIEPPHHEL---NpMRVLLKIAKSEPPTLAQPSR 272 ewdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-* ++ +++kd++kkcL+k+ R+t ++lqHP++ KIAA0204 273 WS---------------SNFKDFLKKCLEKNVDARWTTSQLLQHPFV 304 PF07714.7.fs: domain 1 of 1, from 46 to 292: score 107.0, E = 5.9e-31 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie +++ +LG GaFG+Vyk+ k +t + A K++ + + seee KIAA0204 46 WEIIGELGDGAFGKVYKAQNK----ETSVLAAAKVI-D-TKSEEE-- 84 redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL +ed + E+ i+ + dHpNiV+Ll + + + l+i E+++gG KIAA0204 85 LEDYMVEIDILASC-DHPNIVKLLDAFYY-ENN----LWILIEFCAGGAV 128 ldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLVs + + + +rpLt +++ + Q ++++YL++++++HRDL A N+L + KIAA0204 129 DAVMLEL--ERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFT 176 enlvVKIsDFGLaRdiynddyY.vrkkgggk.lPvkWmAPEslkygk... ++ +K +DFG + + ++ ++ ++ WmAPE+ + +++ KIAA0204 177 LDGDIKLADFGVSAK-----NTrTIQRRDSFiGTPYWMAPEVVMCETskd 221 ..FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyR.Lpr +++ k DVWS G++L E+ e+P ++ + +vl +++++ +L++ KIAA0204 222 rpYDYKADVWSLGITLIEMAE-IEPP-HHELNPMRVLLKIAKSEPPtLAQ 269 PenCPdelYdlMlqCWaedPedR<-* P + d +++C +++ + R KIAA0204 270 PSRWSSNFKDFLKKCLEKNVDAR 292 PF00069.15.ls: domain 1 of 1, from 46 to 304: score 316.7, E = 3.8e-92 *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr +e+++ lG G+fG+Vyka++k t+ + A K+i+ ++e++ +d+ KIAA0204 46 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMV-- 90 lsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdylse Ei il++++HpNIv+l+d+f+++++l++ E+c gG +++ KIAA0204 91 --EIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGG----AVDAVML- 133 trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnngv + ++pl +e +++ +++Q+l +l+YLH+n+iiHRDLK NIL+ +g+ KIAA0204 134 -ELERPL--TESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGD 180 vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvll....ggngyg + K+aDFG+++k t+ ++ ++f GTp++mAPEv++ +++++++y+ KIAA0204 181 I----KLADFGVSAKN-TrTIQrRDSFIGTPYWMAPEVVMcetsKDRPYD 225 tkvDvWSlGvilyelltGkpPFsgevqds.ldqlqlirkilgpplefdsp +k+DvWSlG++l+e++ +pP + ++ + l +i+k +p l +s KIAA0204 226 YKADVWSLGITLIEMAEIEPPHHEL---NpMRVLLKIAKSEPPTLAQPSR 272 ewdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-* ++ +++kd++kkcL+k+ R+t ++lqHP++ KIAA0204 273 WS---------------SNFKDFLKKCLEKNVDARWTTSQLLQHPFV 304 PF07714.7.ls: domain 1 of 1, from 46 to 304: score 106.3, E = 8.5e-29 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie +++ +LG GaFG+Vyk+ k +t + A K++ + + seee KIAA0204 46 WEIIGELGDGAFGKVYKAQNK----ETSVLAAAKVI-D-TKSEEE-- 84 redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL +ed + E+ i+ + dHpNiV+Ll + + + l+i E+++gG KIAA0204 85 LEDYMVEIDILASC-DHPNIVKLLDAFYY-ENN----LWILIEFCAGGAV 128 ldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLVs + + + +rpLt +++ + Q ++++YL++++++HRDL A N+L + KIAA0204 129 DAVMLEL--ERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFT 176 enlvVKIsDFGLaRdiynddyY.vrkkgggk.lPvkWmAPEslkygk... ++ +K +DFG + + ++ ++ ++ WmAPE+ + +++ KIAA0204 177 LDGDIKLADFGVSAK-----NTrTIQRRDSFiGTPYWMAPEVVMCETskd 221 ..FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyR.Lpr +++ k DVWS G++L E+ e+P ++ + +vl +++++ +L++ KIAA0204 222 rpYDYKADVWSLGITLIEMAE-IEPP-HHELNPMRVLLKIAKSEPPtLAQ 269 PenCPdelYdlMlqCWaedPedRPtFsel..veeL<-* P + d +++C +++ + R t s+l ++ + KIAA0204 270 PSRWSSNFKDFLKKCLEKNVDARWTTSQLlqHPFV 304 //