# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/ha01169.fasta.nr -Q ../query/KIAA0142.ptfa /cdna2/lib/nr/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
KIAA0142, 802 aa
vs /cdna2/lib/nr/nr library
2693465022 residues in 7827732 sequences
statistics sampled from 60000 to 7814507 sequences
Expectation_n fit: rho(ln(x))= 5.9108+/-0.000195; mu= 10.5725+/- 0.011
mean_var=109.5650+/-21.034, 0's: 29 Z-trim: 80 B-trim: 82 in 1/65
Lambda= 0.122529
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 38, opt: 26, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7827732)
gi|119629553|gb|EAX09148.1| Rho guanine nucleotide ( 803) 4929 882.6 0
gi|221043142|dbj|BAH13248.1| unnamed protein produ ( 721) 4730 847.4 0
gi|29792236|gb|AAH50521.1| Rho guanine nucleotide ( 764) 4720 845.6 0
gi|114650706|ref|XP_509742.2| PREDICTED: Rho guani ( 901) 4716 845.0 0
gi|194040659|ref|XP_001926031.1| PREDICTED: simila ( 750) 4578 820.5 0
gi|119629550|gb|EAX09145.1| Rho guanine nucleotide ( 782) 4360 782.0 0
gi|21739753|emb|CAD38906.1| hypothetical protein [ ( 812) 4360 782.0 0
gi|119629548|gb|EAX09143.1| Rho guanine nucleotide ( 646) 4257 763.7 0
gi|190690363|gb|ACE86956.1| Rho guanine nucleotide ( 646) 4251 762.6 0
gi|73989539|ref|XP_542671.2| PREDICTED: similar to ( 952) 4221 757.5 5.6e-216
gi|119629551|gb|EAX09146.1| Rho guanine nucleotide ( 753) 4158 746.3 1.1e-212
gi|50403776|sp|Q14155.2|ARHG7_HUMAN RecName: Full= ( 803) 4158 746.3 1.1e-212
gi|126337264|ref|XP_001365011.1| PREDICTED: simila ( 782) 4157 746.1 1.2e-212
gi|194222053|ref|XP_001916719.1| PREDICTED: Rho gu ( 646) 4153 745.3 1.8e-212
gi|45708749|gb|AAH33905.1| ARHGEF7 protein [Homo s ( 753) 4147 744.3 4.1e-212
gi|74226402|dbj|BAE23905.1| unnamed protein produc ( 741) 4139 742.9 1.1e-211
gi|125987791|sp|Q9ES28.2|ARHG7_MOUSE RecName: Full ( 862) 4129 741.2 4.1e-211
gi|165377085|ref|NP_001106989.1| PAK-interacting e ( 782) 4128 741.0 4.3e-211
gi|37788385|gb|AAO65479.1| betaPix-bL [Mus musculu ( 810) 4077 732.0 2.3e-208
gi|126337262|ref|XP_001365087.1| PREDICTED: simila ( 646) 4074 731.4 2.8e-208
gi|18202066|sp|O55043.1|ARHG7_RAT RecName: Full=Rh ( 646) 4063 729.4 1.1e-207
gi|26342753|dbj|BAC35033.1| unnamed protein produc ( 646) 4063 729.4 1.1e-207
gi|2098783|gb|AAB57691.1| p85SPR [Mus musculus] ( 646) 3963 711.7 2.3e-202
gi|7513581|pir||JC5583 85K SH3 domain-containing p ( 646) 3955 710.3 6e-202
gi|194672171|ref|XP_602674.4| PREDICTED: similar t ( 753) 3954 710.2 7.6e-202
gi|189523434|ref|XP_001923598.1| PREDICTED: hypoth ( 802) 3819 686.4 1.2e-194
gi|109745507|gb|ABG46347.1| Rho guanine exchange f ( 799) 3715 668.0 4.2e-189
gi|56270520|gb|AAH86736.1| Rho guanine nucleotide ( 799) 3711 667.3 6.8e-189
gi|55957399|emb|CAI14671.1| Rho guanine nucleotide ( 625) 3688 663.1 9.5e-188
gi|55957400|emb|CAI14672.1| Rho guanine nucleotide ( 705) 3688 663.2 1e-187
gi|126362051|gb|AAI31845.1| Arhgef7 protein [Rattu ( 722) 3583 644.6 4.1e-182
gi|148690136|gb|EDL22083.1| Rho guanine nucleotide ( 705) 3495 629.0 1.9e-177
gi|62750443|gb|AAX98284.1| PAK-interacting exchang ( 705) 3495 629.0 1.9e-177
gi|149057596|gb|EDM08839.1| Rho guanine nucleotide ( 625) 3494 628.8 2e-177
gi|14626418|gb|AAK70212.1| PAK-interacting exchang ( 625) 3494 628.8 2e-177
gi|15420378|gb|AAK97363.1| betaPix-d [Mus musculus ( 625) 3494 628.8 2e-177
gi|10504263|gb|AAG18017.1|AF247654_1 betaPix-b [Mu ( 705) 3446 620.4 7.8e-175
gi|189523436|ref|XP_001923599.1| PREDICTED: hypoth ( 777) 3385 609.6 1.5e-171
gi|169154928|emb|CAQ13260.1| novel protein similar ( 858) 3367 606.5 1.4e-170
gi|109745479|gb|ABG46346.1| Rho guanine exchange f ( 643) 3331 600.0 9.7e-169
gi|221040806|dbj|BAH12080.1| unnamed protein produ ( 547) 3030 546.7 8.9e-153
gi|189528035|ref|XP_686581.3| PREDICTED: similar t ( 795) 2700 488.6 4.3e-135
gi|10504266|gb|AAG18018.1|AF247655_1 betaPix-c [Mu ( 630) 2559 463.5 1.1e-127
gi|47226896|emb|CAG05788.1| unnamed protein produc ( 974) 2251 409.3 3.9e-111
gi|49118990|gb|AAH73669.1| MGC83025 protein [Xenop ( 425) 2137 388.8 2.5e-105
gi|126342501|ref|XP_001363186.1| PREDICTED: simila ( 777) 2098 382.1 4.5e-103
gi|63101169|gb|AAH95868.1| Arhgef7a protein [Danio ( 449) 2065 376.1 1.7e-101
gi|194680183|ref|XP_870250.3| PREDICTED: similar t ( 776) 2035 371.0 1e-99
gi|149755741|ref|XP_001489904.1| PREDICTED: simila ( 776) 2023 368.9 4.4e-99
gi|109132455|ref|XP_001083544.1| PREDICTED: Rac/Cd ( 776) 2023 368.9 4.4e-99
>>gi|119629553|gb|EAX09148.1| Rho guanine nucleotide exc (803 aa)
initn: 4929 init1: 4929 opt: 4929 Z-score: 4711.1 bits: 882.6 E(): 0
Smith-Waterman score: 4929; 99.468% identity (99.867% similar) in 752 aa overlap (51-802:52-803)
30 40 50 60 70 80
KIAA01 RPLCWERGPWASLGLVRGVPAAGHGAQRLCSVLQVYPEPRSESECLSNIREFLRGCGASL
.. .::::::::::::::::::::::::::
gi|119 KTISDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASL
30 40 50 60 70 80
90 100 110 120 130 140
KIAA01 RLETFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 RLETFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSL
90 100 110 120 130 140
150 160 170 180 190 200
KIAA01 HTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 HTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWW
150 160 170 180 190 200
210 220 230 240 250 260
KIAA01 EGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILET
210 220 230 240 250 260
270 280 290 300 310 320
KIAA01 ENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEECTKLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEECTKLPEA
270 280 290 300 310 320
330 340 350 360 370 380
KIAA01 QQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSPGILVLTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSPGILVLTTG
330 340 350 360 370 380
390 400 410 420 430 440
KIAA01 LSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQIL
390 400 410 420 430 440
450 460 470 480 490 500
KIAA01 TEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 TEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIY
450 460 470 480 490 500
510 520 530 540 550 560
KIAA01 QGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSV
510 520 530 540 550 560
570 580 590 600 610 620
KIAA01 GNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHPSHHGTPHTTINWGPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHPSHHGTPHTTINWGPLE
570 580 590 600 610 620
630 640 650 660 670 680
KIAA01 PPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRKPERKPSDEEFASRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRKPERKPSDEEFASRK
630 640 650 660 670 680
690 700 710 720 730 740
KIAA01 STAALEEDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQVLLPEEEKIIVEETKSNGQTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 STAALEEDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQVLLPEEEKIIVEETKSNGQTV
690 700 710 720 730 740
750 760 770 780 790 800
KIAA01 IEEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 IEEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDET
750 760 770 780 790 800
KIAA01 NL
::
gi|119 NL
>>gi|221043142|dbj|BAH13248.1| unnamed protein product [ (721 aa)
initn: 4730 init1: 4730 opt: 4730 Z-score: 4521.6 bits: 847.4 E(): 0
Smith-Waterman score: 4730; 99.723% identity (100.000% similar) in 721 aa overlap (82-802:1-721)
60 70 80 90 100 110
KIAA01 VLQVYPEPRSESECLSNIREFLRGCGASLRLETFDANDLYQGQNFNKVLSSLVTLNKVTA
..::::::::::::::::::::::::::::
gi|221 MKTFDANDLYQGQNFNKVLSSLVTLNKVTA
10 20 30
120 130 140 150 160 170
KIAA01 DIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|221 DIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKF
40 50 60 70 80 90
180 190 200 210 220 230
KIAA01 NFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|221 NFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSG
100 110 120 130 140 150
240 250 260 270 280 290
KIAA01 TLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|221 TLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANIS
160 170 180 190 200 210
300 310 320 330 340 350
KIAA01 YLMGNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|221 YLMGNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVN
220 230 240 250 260 270
360 370 380 390 400 410
KIAA01 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|221 VLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQD
280 290 300 310 320 330
420 430 440 450 460 470
KIAA01 IQKSMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|221 IQKSMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGS
340 350 360 370 380 390
480 490 500 510 520 530
KIAA01 EEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|221 EEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMI
400 410 420 430 440 450
540 550 560 570 580 590
KIAA01 ERILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|221 ERILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKP
460 470 480 490 500 510
600 610 620 630 640 650
KIAA01 APLTPAYHTLPHPSHHGTPHTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|221 APLTPAYHTLPHPSHHGTPHTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDL
520 530 540 550 560 570
660 670 680 690 700 710
KIAA01 SKSPKTMKKLLPKRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|221 SKSPKTMKKLLPKRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSS
580 590 600 610 620 630
720 730 740 750 760 770
KIAA01 SRKESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNKKMKKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|221 SRKESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNKKMKKSL
640 650 660 670 680 690
780 790 800
KIAA01 EEEQRARKDLEKLVRKVLKNMNDPAWDETNL
:::::::::::::::::::::::::::::::
gi|221 EEEQRARKDLEKLVRKVLKNMNDPAWDETNL
700 710 720
>>gi|29792236|gb|AAH50521.1| Rho guanine nucleotide exch (764 aa)
initn: 4720 init1: 4720 opt: 4720 Z-score: 4511.7 bits: 845.6 E(): 0
Smith-Waterman score: 4720; 99.861% identity (99.861% similar) in 719 aa overlap (84-802:46-764)
60 70 80 90 100 110
KIAA01 QVYPEPRSESECLSNIREFLRGCGASLRLETFDANDLYQGQNFNKVLSSLVTLNKVTADI
::::::::::::::::::::::::::::::
gi|297 ISRSGLFGVYYVEVHQPALPWRQEAFFCSRTFDANDLYQGQNFNKVLSSLVTLNKVTADI
20 30 40 50 60 70
120 130 140 150 160 170
KIAA01 GLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|297 GLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNF
80 90 100 110 120 130
180 190 200 210 220 230
KIAA01 QQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|297 QQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTL
140 150 160 170 180 190
240 250 260 270 280 290
KIAA01 KSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|297 KSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYL
200 210 220 230 240 250
300 310 320 330 340 350
KIAA01 MGNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|297 MGNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVL
260 270 280 290 300 310
360 370 380 390 400 410
KIAA01 TEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|297 TEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQ
320 330 340 350 360 370
420 430 440 450 460 470
KIAA01 KSMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|297 KSMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEE
380 390 400 410 420 430
480 490 500 510 520 530
KIAA01 KNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|297 KNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIER
440 450 460 470 480 490
540 550 560 570 580 590
KIAA01 ILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|297 ILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAP
500 510 520 530 540 550
600 610 620 630 640 650
KIAA01 LTPAYHTLPHPSHHGTPHTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSK
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
gi|297 LTPAYHTLPHPSHHGTPHTTTNWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSK
560 570 580 590 600 610
660 670 680 690 700 710
KIAA01 SPKTMKKLLPKRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|297 SPKTMKKLLPKRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSSSR
620 630 640 650 660 670
720 730 740 750 760 770
KIAA01 KESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNKKMKKSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|297 KESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNKKMKKSLEE
680 690 700 710 720 730
780 790 800
KIAA01 EQRARKDLEKLVRKVLKNMNDPAWDETNL
:::::::::::::::::::::::::::::
gi|297 EQRARKDLEKLVRKVLKNMNDPAWDETNL
740 750 760
>>gi|114650706|ref|XP_509742.2| PREDICTED: Rho guanine n (901 aa)
initn: 4716 init1: 4716 opt: 4716 Z-score: 4506.9 bits: 845.0 E(): 0
Smith-Waterman score: 4862; 97.013% identity (97.143% similar) in 770 aa overlap (54-802:132-901)
30 40 50 60 70 80
KIAA01 CWERGPWASLGLVRGVPAAGHGAQRLCSVLQVYPEPRSESECLSNIREFLRGCGASLRLE
.:::::::::::::::::::::::::::::
gi|114 ARSEDVTSGAGAHFLVREGAEIGAAPEEEKRVYPEPRSESECLSNIREFLRGCGASLRLE
110 120 130 140 150 160
90 100 110 120
KIAA01 ---------------------TFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCA
:::::::::::::::::::::::::::::::::::::::
gi|114 LLFPPSQPPQHLVTTVLLSASTFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCA
170 180 190 200 210 220
130 140 150 160 170 180
KIAA01 RPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 RPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELS
230 240 250 260 270 280
190 200 210 220 230 240
KIAA01 FSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 FSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDT
290 300 310 320 330 340
250 260 270 280 290 300
KIAA01 TAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 TAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICS
350 360 370 380 390 400
310 320 330 340 350 360
KIAA01 FQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 FQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGE
410 420 430 440 450 460
370 380 390 400 410 420
KIAA01 FMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 FMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNL
470 480 490 500 510 520
430 440 450 460 470 480
KIAA01 SAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLF
530 540 550 560 570 580
490 500 510 520 530 540
KIAA01 PNVLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PNVLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQ
590 600 610 620 630 640
550 560 570 580 590 600
KIAA01 DLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLP
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
gi|114 DLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHAVTPSSKHADSKPAPLTPAYHTLP
650 660 670 680 690 700
610 620 630 640 650 660
KIAA01 HPSHHGTPHTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 HPSHHGTPHTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLL
710 720 730 740 750 760
670 680 690 700 710 720
KIAA01 PKRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PKRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQVLL
770 780 790 800 810 820
730 740 750 760 770 780
KIAA01 PEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 PEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLE
830 840 850 860 870 880
790 800
KIAA01 KLVRKVLKNMNDPAWDETNL
::::::::::::::::::::
gi|114 KLVRKVLKNMNDPAWDETNL
890 900
>>gi|194040659|ref|XP_001926031.1| PREDICTED: similar to (750 aa)
initn: 4578 init1: 4578 opt: 4578 Z-score: 4376.1 bits: 820.5 E(): 0
Smith-Waterman score: 4578; 94.498% identity (98.762% similar) in 727 aa overlap (76-802:24-750)
50 60 70 80 90 100
KIAA01 AQRLCSVLQVYPEPRSESECLSNIREFLRGCGASLRLETFDANDLYQGQNFNKVLSSLVT
:: :::::::::::::::::::::::::::
gi|194 MVEPIGGHFSQPDASWRPAVSLPCGCSLRLETFDANDLYQGQNFNKVLSSLVT
10 20 30 40 50
110 120 130 140 150 160
KIAA01 LNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQL
::::::::::::::::::::::::::::::::: :.:::::::::::::::.:::..::
gi|194 LNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQPSHARTSKLFQGQYRSLDMSDNSSSQL
60 70 80 90 100 110
170 180 190 200 210 220
KIAA01 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKP
::::::::::::::::::..:::::::::::::::::::.::::::::::::::: ::::
gi|194 VVRAKFNFQQTNEDELSFARGDVIHVTRVEEGGWWEGTLDGRTGWFPSNYVREVKPSEKP
120 130 140 150 160 170
230 240 250 260 270 280
KIAA01 VSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKL
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
gi|194 VSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSAYLRPLQTSEKL
180 190 200 210 220 230
290 300 310 320 330 340
KIAA01 SSANISYLMGNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCAN
::::.::::::::::::::::::::::::::.::::::::::::.::::::::::.::::
gi|194 SSANMSYLMGNLEEICSFQQMLVQSLEECTKVPEAQQRVGGCFLSLMPQMKTLYLAYCAN
240 250 260 270 280 290
350 360 370 380 390 400
KIAA01 HPSAVNVLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDY
:::::.:::.:::::::::: :::::::.::::::::::::::::::.::::::::::::
gi|194 HPSAVSVLTQHSEELGEFMEMKGASSPGVLVLTTGLSKPFMRLDKYPALLKELERHMEDY
300 310 320 330 340 350
410 420 430 440 450 460
KIAA01 HTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVL
: :::::::::.::::::::::::::::::::::::::::.::::::::::.: .:::::
gi|194 HPDRQDIQKSMTAFKNLSAQCQEVRKRKELELQILTEAIRSWEGDDIKTLGHVIHMSQVL
360 370 380 390 400 410
470 480 490 500 510 520
KIAA01 IQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFE
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
gi|194 IQCAGSEEKNERYLLLFPNILLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFE
420 430 440 450 460 470
530 540 550 560 570 580
KIAA01 ISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSK
:::::::::::::.:::::.:::.::::::::::.:::::::::::::::::: .:::::
gi|194 ISGSMIERILVSCSNQQDLHEWVDHLQKQTKVTSAGNPTIKPHSVPSHTLPSHSITPSSK
480 490 500 510 520 530
590 600 610 620 630 640
KIAA01 HADSKPAPLTPAYHTLPHPSHHGTPHTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAAL
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 HADSKPAPLTPTYHTLPHPSHHGTPHTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAAL
540 550 560 570 580 590
650 660 670 680 690 700
KIAA01 CYKEDLSKSPKTMKKLLPKRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTR
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
gi|194 CYKEDLSKSPKTMKKLLPKRKPERKPSDEEFALRKSTAALEEDAQILKVIEAYCTSAKTR
600 610 620 630 640 650
710 720 730 740 750 760
KIAA01 QTLNSSSRKESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|194 QTLNSSSRKESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNK
660 670 680 690 700 710
770 780 790 800
KIAA01 KMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETNL
:::::::.:::::.:::::.:::::.:::::::::::
gi|194 KMKKSLEDEQRARRDLEKLLRKVLKSMNDPAWDETNL
720 730 740 750
>>gi|119629550|gb|EAX09145.1| Rho guanine nucleotide exc (782 aa)
initn: 4397 init1: 4355 opt: 4360 Z-score: 4167.6 bits: 782.0 E(): 0
Smith-Waterman score: 4360; 99.244% identity (99.849% similar) in 661 aa overlap (51-711:52-712)
30 40 50 60 70 80
KIAA01 RPLCWERGPWASLGLVRGVPAAGHGAQRLCSVLQVYPEPRSESECLSNIREFLRGCGASL
.. .::::::::::::::::::::::::::
gi|119 KTISDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASL
30 40 50 60 70 80
90 100 110 120 130 140
KIAA01 RLETFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 RLETFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSL
90 100 110 120 130 140
150 160 170 180 190 200
KIAA01 HTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 HTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWW
150 160 170 180 190 200
210 220 230 240 250 260
KIAA01 EGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 EGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILET
210 220 230 240 250 260
270 280 290 300 310 320
KIAA01 ENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEECTKLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 ENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEECTKLPEA
270 280 290 300 310 320
330 340 350 360 370 380
KIAA01 QQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSPGILVLTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSPGILVLTTG
330 340 350 360 370 380
390 400 410 420 430 440
KIAA01 LSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQIL
390 400 410 420 430 440
450 460 470 480 490 500
KIAA01 TEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 TEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIY
450 460 470 480 490 500
510 520 530 540 550 560
KIAA01 QGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSV
510 520 530 540 550 560
570 580 590 600 610 620
KIAA01 GNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHPSHHGTPHTTINWGPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 GNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHPSHHGTPHTTINWGPLE
570 580 590 600 610 620
630 640 650 660 670 680
KIAA01 PPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRKPERKPSDEEFASRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRKPERKPSDEEFASRK
630 640 650 660 670 680
690 700 710 720 730 740
KIAA01 STAALEEDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQVLLPEEEKIIVEETKSNGQTV
::::::::::::::::::::::::::::::.
gi|119 STAALEEDAQILKVIEAYCTSAKTRQTLNSTWQGTDLMHNHVLADDDQPSLDSLGRRSSL
690 700 710 720 730 740
750 760 770 780 790 800
KIAA01 IEEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDET
gi|119 SRLEPSDLSEDSDYDSIWTAHSYRMGSTSRKSCCSYISHQN
750 760 770 780
>>gi|21739753|emb|CAD38906.1| hypothetical protein [Homo (812 aa)
initn: 4397 init1: 4355 opt: 4360 Z-score: 4167.4 bits: 782.0 E(): 0
Smith-Waterman score: 4360; 99.244% identity (99.849% similar) in 661 aa overlap (51-711:82-742)
30 40 50 60 70 80
KIAA01 RPLCWERGPWASLGLVRGVPAAGHGAQRLCSVLQVYPEPRSESECLSNIREFLRGCGASL
.. .::::::::::::::::::::::::::
gi|217 KTISDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASL
60 70 80 90 100 110
90 100 110 120 130 140
KIAA01 RLETFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|217 RLETFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSL
120 130 140 150 160 170
150 160 170 180 190 200
KIAA01 HTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|217 HTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWW
180 190 200 210 220 230
210 220 230 240 250 260
KIAA01 EGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|217 EGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILET
240 250 260 270 280 290
270 280 290 300 310 320
KIAA01 ENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEECTKLPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|217 ENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEECTKLPEA
300 310 320 330 340 350
330 340 350 360 370 380
KIAA01 QQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSPGILVLTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|217 QQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSPGILVLTTG
360 370 380 390 400 410
390 400 410 420 430 440
KIAA01 LSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|217 LSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQIL
420 430 440 450 460 470
450 460 470 480 490 500
KIAA01 TEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|217 TEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIY
480 490 500 510 520 530
510 520 530 540 550 560
KIAA01 QGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|217 QGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSV
540 550 560 570 580 590
570 580 590 600 610 620
KIAA01 GNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHPSHHGTPHTTINWGPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|217 GNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHPSHHGTPHTTINWGPLE
600 610 620 630 640 650
630 640 650 660 670 680
KIAA01 PPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRKPERKPSDEEFASRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|217 PPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRKPERKPSDEEFASRK
660 670 680 690 700 710
690 700 710 720 730 740
KIAA01 STAALEEDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQVLLPEEEKIIVEETKSNGQTV
::::::::::::::::::::::::::::::.
gi|217 STAALEEDAQILKVIEAYCTSAKTRQTLNSTWQGTDLMHNHVLADDDQPSLDSLGRRSSL
720 730 740 750 760 770
750 760 770 780 790 800
KIAA01 IEEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDET
gi|217 SRLEPSDLSEDSDYDSIWTAHSYRMGSTSRKSCCSYISHQN
780 790 800 810
>>gi|119629548|gb|EAX09143.1| Rho guanine nucleotide exc (646 aa)
initn: 4257 init1: 4257 opt: 4257 Z-score: 4070.3 bits: 763.7 E(): 0
Smith-Waterman score: 4257; 100.000% identity (100.000% similar) in 646 aa overlap (157-802:1-646)
130 140 150 160 170 180
KIAA01 HRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKG
::::::::::::::::::::::::::::::
gi|119 MTDNSNNQLVVRAKFNFQQTNEDELSFSKG
10 20 30
190 200 210 220 230 240
KIAA01 DVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 DVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAIN
40 50 60 70 80 90
250 260 270 280 290 300
KIAA01 KSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQM
100 110 120 130 140 150
310 320 330 340 350 360
KIAA01 LVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMET
160 170 180 190 200 210
370 380 390 400 410 420
KIAA01 KGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQC
220 230 240 250 260 270
430 440 450 460 470 480
KIAA01 QEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 QEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVL
280 290 300 310 320 330
490 500 510 520 530 540
KIAA01 LMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQE
340 350 360 370 380 390
550 560 570 580 590 600
KIAA01 WVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 WVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHPSH
400 410 420 430 440 450
610 620 630 640 650 660
KIAA01 HGTPHTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 HGTPHTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRK
460 470 480 490 500 510
670 680 690 700 710 720
KIAA01 PERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQVLLPEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 PERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQVLLPEEE
520 530 540 550 560 570
730 740 750 760 770 780
KIAA01 KIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 KIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVR
580 590 600 610 620 630
790 800
KIAA01 KVLKNMNDPAWDETNL
::::::::::::::::
gi|119 KVLKNMNDPAWDETNL
640
>>gi|190690363|gb|ACE86956.1| Rho guanine nucleotide exc (646 aa)
initn: 4251 init1: 4251 opt: 4251 Z-score: 4064.6 bits: 762.6 E(): 0
Smith-Waterman score: 4251; 99.845% identity (99.845% similar) in 646 aa overlap (157-802:1-646)
130 140 150 160 170 180
KIAA01 HRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKG
::::::::::::::::::::::::::::::
gi|190 MTDNSNNQLVVRAKFNFQQTNEDELSFSKG
10 20 30
190 200 210 220 230 240
KIAA01 DVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|190 DVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAIN
40 50 60 70 80 90
250 260 270 280 290 300
KIAA01 KSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|190 KSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQM
100 110 120 130 140 150
310 320 330 340 350 360
KIAA01 LVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|190 LVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMET
160 170 180 190 200 210
370 380 390 400 410 420
KIAA01 KGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|190 KGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQC
220 230 240 250 260 270
430 440 450 460 470 480
KIAA01 QEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|190 QEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVL
280 290 300 310 320 330
490 500 510 520 530 540
KIAA01 LMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|190 LMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQE
340 350 360 370 380 390
550 560 570 580 590 600
KIAA01 WVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|190 WVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHPSH
400 410 420 430 440 450
610 620 630 640 650 660
KIAA01 HGTPHTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRK
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|190 HGTPHTTTNWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRK
460 470 480 490 500 510
670 680 690 700 710 720
KIAA01 PERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQVLLPEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|190 PERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQVLLPEEE
520 530 540 550 560 570
730 740 750 760 770 780
KIAA01 KIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|190 KIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVR
580 590 600 610 620 630
790 800
KIAA01 KVLKNMNDPAWDETNL
::::::::::::::::
gi|190 KVLKNMNDPAWDETNL
640
>>gi|73989539|ref|XP_542671.2| PREDICTED: similar to Rho (952 aa)
initn: 4295 init1: 4220 opt: 4221 Z-score: 4033.7 bits: 757.5 E(): 5.6e-216
Smith-Waterman score: 4682; 84.501% identity (88.175% similar) in 871 aa overlap (10-802:91-952)
10 20 30
KIAA01 AGWHLGQRARSRPSGAARQRRPLCWERGPWASLGLVRGV
:.:: :::. : : :: .::
gi|739 RALLGPSGQGGVRVGEAEAEAEAESARAWGRARPEEAARSGR---WGRGLKTSL------
70 80 90 100 110
40 50 60 70 80
KIAA01 PAAGHGAQRL----------C---------SVLQVYPEPRSESECLSNIREFLRGCGASL
:::.: .:: : :::::::::::::::::.::::::::::::
gi|739 PAAAHFLERLAGAAVVAPRACAPPLSACALSVLQVYPEPRSESECLSHIREFLRGCGASL
120 130 140 150 160 170
90 100 110 120 130 140
KIAA01 RLETFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
gi|739 RLETFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGAQPS
180 190 200 210 220 230
150 160 170 180 190 200
KIAA01 HTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWW
:.::::::::::::::::::::.::::::::::::::::::::.::::::::::::::::
gi|739 HSRTSKLFQGQYRSLDMTDNSNSQLVVRAKFNFQQTNEDELSFTKGDVIHVTRVEEGGWW
240 250 260 270 280 290
210 220 230 240 250 260
KIAA01 EGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILET
::: ::.:::::::::::.: ::::::::::.::::::::::::::::::::::::::::
gi|739 EGTHNGKTGWFPSNYVREMKPSEKPVSPKSGALKSPPKGFDTTAINKSYYNVVLQNILET
300 310 320 330 340 350
270 280 290 300 310 320
KIAA01 ENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEECTKLPEA
::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
gi|739 ENEYSKELQTVLSTYLRPLQTSEKLSSANTSYLMGNLEEICSFQQMLVQSLEECTKLPEA
360 370 380 390 400 410
330 340 350 360 370 380
KIAA01 QQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSPGILVLTTG
::::::::::::::::::::.:::::::::::::::::.::::::..:::::::::::::
gi|739 QQRVGGCFLNLMPQMKTLYLAYCANHPSAVNVLTEHSEQLGEFMEARGASSPGILVLTTG
420 430 440 450 460 470
390 400 410 420 430 440
KIAA01 LSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQIL
::.::::::::::::::::::::::: :::::::::.:::::::::::::::::::::::
gi|739 LSRPFMRLDKYPTLLKELERHMEDYHPDRQDIQKSMTAFKNLSAQCQEVRKRKELELQIL
480 490 500 510 520 530
450 460 470 480 490 500
KIAA01 TEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIY
:::::.:::::: :::.:.:::::..::::::::::::::::::.:::::::::::::::
gi|739 TEAIRSWEGDDITTLGSVVYMSQVMVQCAGSEEKNERYLLLFPNILLMLSASPRMSGFIY
540 550 560 570 580 590
510 520 530 540 550 560
KIAA01 QGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSV
::::::::::::::::::::::::::::::::::::::::::::.:::.:::::::::::
gi|739 QGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLHEWVDHLQKQTKVTSV
600 610 620 630 640 650
570 580 590 600 610 620
KIAA01 GNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHPSHHGTPHTTINWGPLE
:::::::::::::::::::..::::::::::.::::::::::::::::::::::::::::
gi|739 GNPTIKPHSVPSHTLPSHPIAPSSKHADSKPVPLTPAYHTLPHPSHHGTPHTTINWGPLE
660 670 680 690 700 710
630 640 650 660 670 680
KIAA01 PPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRKPERKPSDEEFASRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
gi|739 PPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRKPERKPSDEEFALRK
720 730 740 750 760 770
690 700 710
KIAA01 STAALEEDAQILKVIEAYCTSAKTRQTLNSS-----------------------------
::::::::::::::::::::::::::::::.
gi|739 STAALEEDAQILKVIEAYCTSAKTRQTLNSTWQGTDLMHNHVLADDDQSSLDSLGRRSSL
780 790 800 810 820 830
720 730 740
KIAA01 ------------------------------SRKESAPQVLLPEEEKIIVEETKSNGQTVI
::::::::::::::::.:::::::::::::
gi|739 SRLEPSDLSEDSDYDSIWTAHSYRMGSTSRSRKESAPQVLLPEEEKMIVEETKSNGQTVI
840 850 860 870 880 890
750 760 770 780 790 800
KIAA01 EEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 EEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETN
900 910 920 930 940 950
KIAA01 L
:
gi|739 L
802 residues in 1 query sequences
2693465022 residues in 7827732 library sequences
Tcomplib [34.26] (8 proc)
start: Wed Mar 4 00:06:56 2009 done: Wed Mar 4 00:10:31 2009
Total Scan time: 1592.740 Total Display time: 0.450
Function used was FASTA [version 34.26.5 April 26, 2007]