hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080501/iprscan-20080501-18232795/chunk_1/iprscan-20080501-18232795.nocrc
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Query sequence: KIAA0137
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
PF00069.15.ls Protein kinase domain                       229.2    8.3e-66   1
PF00069.15.fs Protein kinase domain                       227.3    3.1e-65   1
PF07714.7.fs Protein tyrosine kinase                      65.0    9.2e-19   2

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
PF00069.15.fs   1/1     491   769 ..     1   287 []   227.3  3.1e-65
PF00069.15.ls   1/1     491   769 ..     1   287 []   229.2  8.3e-66
PF07714.7.fs   2/2     542   697 ..    53   204 ..    60.8  1.5e-17

Alignments of top-scoring domains:
PF00069.15.fs: domain 1 of 1, from 491 to 769: score 227.3, E = 3.1e-65
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKi..ikkrkekskkdkta
                      y ll  lG+G+f++Vyka +  +++  AvKi++++k+ +++kk+ ++
    KIAA0137   491    YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIhqLNKSWRDEKKENYH 537  

                   rrl.sEiqilkrLsHpNIvrlidvfed.kdhlylVlEycegGLrvldLfd
                    ++ +E +i+k+L+Hp Iv+l+d+f  + d  + VlEyceg     dL  
    KIAA0137   538 KHAcREYRIHKELDHPRIVKLYDYFSLdTDTFCTVLEYCEGN----DLDF 583  

                   ylsetrrkgpllfsedeakkialQilrgleYLHsn..giiHRDLKPeNIL
                   yl+   +++ +  se+ea++i+ Qi+ +l YL + ++ iiH DLKP NIL
    KIAA0137   584 YLK---QHKLM--SEKEARSIVMQIVNALRYLNEIkpPIIHYDLKPGNIL 628  

                   ldnngvvdaflKiaDFGlAkkls.....t.sss.lttfvGTpwYmAPEvl
                   l+ +g+ +  +Ki+DFGl+k +++++ + +    ++  +GT+wY++PE  
    KIAA0137   629 LV-DGTACGEIKITDFGLSKIMDddsygVdGMDlTSQGAGTYWYLPPECF 677  

                   l...ggngygtkvDvWSlGvilyelltGkpPFs.gevqds.ldqlqlirk
                     +++ ++++ kvDvWS+Gvi+++ l G+ PF +++   s+ d lq    
    KIAA0137   678 VvgkEPPKISNKVDVWSVGVIFFQCLYGRKPFGhNQ---SqQDILQENTI 724  

                   ilgpplefdspewdsisrsefrrlpnlseeakdLikkcLnkDPskRltae
                    + +++ f+     s             +eak +i++cL++  ++R   +
    KIAA0137   725 LKATEVQFPVKPVVS-------------SEAKAFIRRCLAYRKEDRFDVH 761  

                   eilqHPwf<-*
                   ++ ++P++   
    KIAA0137   762 QLANDPYL    769  

PF00069.15.ls: domain 1 of 1, from 491 to 769: score 229.2, E = 8.3e-66
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKi..ikkrkekskkdkta
                      y ll  lG+G+f++Vyka +  +++  AvKi++++k+ +++kk+ ++
    KIAA0137   491    YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIhqLNKSWRDEKKENYH 537  

                   rrl.sEiqilkrLsHpNIvrlidvfed.kdhlylVlEycegGLrvldLfd
                    ++ +E +i+k+L+Hp Iv+l+d+f  + d  + VlEyceg     dL  
    KIAA0137   538 KHAcREYRIHKELDHPRIVKLYDYFSLdTDTFCTVLEYCEGN----DLDF 583  

                   ylsetrrkgpllfsedeakkialQilrgleYLHsn..giiHRDLKPeNIL
                   yl+   +++ +  se+ea++i+ Qi+ +l YL + ++ iiH DLKP NIL
    KIAA0137   584 YLK---QHKLM--SEKEARSIVMQIVNALRYLNEIkpPIIHYDLKPGNIL 628  

                   ldnngvvdaflKiaDFGlAkkls.....t.sss.lttfvGTpwYmAPEvl
                   l+ +g+ +  +Ki+DFGl+k +++++ + +    ++  +GT+wY++PE  
    KIAA0137   629 LV-DGTACGEIKITDFGLSKIMDddsygVdGMDlTSQGAGTYWYLPPECF 677  

                   l...ggngygtkvDvWSlGvilyelltGkpPFs.gevqds.ldqlqlirk
                     +++ ++++ kvDvWS+Gvi+++ l G+ PF +++   s+ d lq    
    KIAA0137   678 VvgkEPPKISNKVDVWSVGVIFFQCLYGRKPFGhNQ---SqQDILQENTI 724  

                   ilgpplefdspewdsisrsefrrlpnlseeakdLikkcLnkDPskRltae
                    + +++ f+     s             +eak +i++cL++  ++R   +
    KIAA0137   725 LKATEVQFPVKPVVS-------------SEAKAFIRRCLAYRKEDRFDVH 761  

                   eilqHPwf<-*
                   ++ ++P++   
    KIAA0137   762 QLANDPYL    769  

PF07714.7.fs: domain 2 of 2, from 542 to 697: score 60.8, E = 1.5e-17
                   *->rEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdLld
                      rE +i k+l dHp iV+L+   + + +      + V+Ey+eg dL+ 
    KIAA0137   542    REYRIHKEL-DHPRIVKLYDYFSLDTDT----FCTVLEYCEGNDLDF 583  

                   fLrkhregrpLtlkdLlsfalQiAkGMeYLeskn..fvHRDLAARNcLVs
                   +L++h   +  + k+  s+ +Qi +++ YL + +++++H DL   N+L+ 
    KIAA0137   584 YLKQH---KLMSEKEARSIVMQIVNALRYLNEIKppIIHYDLKPGNILLV 630  

                   e...nlvVKIsDFGLaRdiynddyYvrkkgggklPv....kWm.APEslk
                   +++  + +KI+DFGL++ + +dd Y  + g      + ++ W+ +PE++ 
    KIAA0137   631 DgtaCGEIKITDFGLSKIM-DDDSY-GVDGMDLTSQgagtYWYlPPECFV 678  

                   ygk....FtskSDVWSFGV<-*
                    gk++++ + k DVWS GV   
    KIAA0137   679 VGKeppkISNKVDVWSVGV    697  

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