Nr search
BLASTX 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= KCC000063A_C01 KCC000063A_c01
(1894 letters)
Database: nr
1,537,769 sequences; 498,525,298 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
emb|CAC18798.1| cathepsin Z [Cricetulus griseus] 335 2e-90
gb|AAC39839.1| cathepsin Z precursor; CTSZ [Homo sapiens] 328 2e-88
ref|NP_001327.2| cathepsin Z preproprotein; cathepsin X precurso... 328 2e-88
ref|NP_899159.1| cathepsin Y [Rattus norvegicus] gi|34978341|sp|... 328 2e-88
gb|AAC63141.1| preprocathepsin P [Homo sapiens] 328 2e-88
>emb|CAC18798.1| cathepsin Z [Cricetulus griseus]
Length = 306
Score = 335 bits (859), Expect = 2e-90
Identities = 161/309 (52%), Positives = 204/309 (65%), Gaps = 2/309 (0%)
Frame = +2
Query: 62 PQLLVLALALAAGTAHGKVVLRESTGRPSRYASTIVRHEDIPEL--ITTPRSHELISEKD 235
P+L++L L LA G A + R P R +R + I +L T PR HE +S D
Sbjct: 10 PRLVLLMLVLA-GAARASLYFR-----PGRTCYHPLRGDQIAQLGRRTYPRPHEYLSPSD 63
Query: 236 LPREWDWRAVPSSANSDDRHNYLSIIRNQHIPKYCGSCWAHGASSSLADRMNIKMKGAWP 415
+P+ WDWR V NY SI RNQHIP+YCGSCWAHG++S++ADR+NIK KGAWP
Sbjct: 64 IPKNWDWRNVKGV-------NYASITRNQHIPQYCGSCWAHGSTSAMADRINIKRKGAWP 116
Query: 416 GTFLSVQNIIDCGGAGSCNGGDDRLVYVYGAKHGIPPDTCNLYVAANQKCHAMQQCFTCW 595
T LSVQN+IDCG AGSC GG+D V+ Y KHGIP +TCN Y A +Q C QC TC
Sbjct: 117 STLLSVQNVIDCGNAGSCEGGNDLPVWAYAHKHGIPDETCNNYQAKDQDCDKFNQCGTCT 176
Query: 596 PDSTCEPIYDYKRLTVSEHGRVRGRYQMKAEIYKRGPISCGIDATDQLETYTGGVYAERK 775
C I +Y R V ++G + GR +M AEIY GPISCGI T++++ YTGG+YAE +
Sbjct: 177 EFKVCHTIQNYTRWRVGDYGSLSGREKMMAEIYANGPISCGIMVTEKMDNYTGGIYAELQ 236
Query: 776 SNPSINHVVSVVGWGVDPETDVEYWVIRNSWGEPWGESGFLKLVTSAYDDGNGNMYNLAI 955
SINH+VSV GWGV + +EYW++RNSWGEPWGE G++++VTS Y G G YNLAI
Sbjct: 237 EQTSINHIVSVAGWGVSSD-GIEYWIVRNSWGEPWGERGWMRIVTSTYKGGTGASYNLAI 295
Query: 956 EDDCNFGVP 982
E+ C +G P
Sbjct: 296 EEACTYGDP 304
>gb|AAC39839.1| cathepsin Z precursor; CTSZ [Homo sapiens]
Length = 303
Score = 328 bits (842), Expect = 2e-88
Identities = 163/307 (53%), Positives = 201/307 (65%), Gaps = 4/307 (1%)
Frame = +2
Query: 74 VLALALAAGTAHGKVVLR--ESTGRPSRYASTIVRHEDIPEL--ITTPRSHELISEKDLP 241
+L L L AG A G + R ++ RP +R + + L T PR HE +S DLP
Sbjct: 11 LLLLVLLAGAAQGGLYFRRGQTCYRP-------LRGDGLAPLGRTTYPRPHEYLSPADLP 63
Query: 242 REWDWRAVPSSANSDDRHNYLSIIRNQHIPKYCGSCWAHGASSSLADRMNIKMKGAWPGT 421
+ WDWR V D NY SI RNQHIP+YCGSCWAH ++S++ADR+NIK KGAWP T
Sbjct: 64 KSWDWRNV-------DGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPST 116
Query: 422 FLSVQNIIDCGGAGSCNGGDDRLVYVYGAKHGIPPDTCNLYVAANQKCHAMQQCFTCWPD 601
LSVQN+IDCG AGSC GG+D V+ Y +HGIP +TCN Y A +Q+C QC TC
Sbjct: 117 LLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEF 176
Query: 602 STCEPIYDYKRLTVSEHGRVRGRYQMKAEIYKRGPISCGIDATDQLETYTGGVYAERKSN 781
C I +Y V ++G + GR +M AEIY GPISCGI AT++L YTGG+YAE +
Sbjct: 177 KECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDT 236
Query: 782 PSINHVVSVVGWGVDPETDVEYWVIRNSWGEPWGESGFLKLVTSAYDDGNGNMYNLAIED 961
INHVVSV GWG+ T EYW++RNSWGEPWGE G+L++VTS Y DG G YNLAIE+
Sbjct: 237 TYINHVVSVAGWGISDGT--EYWIVRNSWGEPWGERGWLRIVTSTYKDGKGARYNLAIEE 294
Query: 962 DCNFGVP 982
C FG P
Sbjct: 295 HCTFGDP 301
>ref|NP_001327.2| cathepsin Z preproprotein; cathepsin X precursor; preprocathepsin
P; cathepsin Z precursor [Homo sapiens]
gi|12643324|sp|Q9UBR2|CATZ_HUMAN Cathepsin Z precursor
(Cathepsin X) (Cathepsin P)
gi|6467380|gb|AAF13145.1|AF136273_1 cathepsin Z
precursor [Homo sapiens] gi|6467389|gb|AAF13148.1|
cathepsin Z precursor [Homo sapiens]
gi|10241506|emb|CAC09370.1| dJ543J19.3.1 (cathepsin Z
(CTSX), variant 1) [Homo sapiens]
gi|27503311|gb|AAH42168.1| Cathepsin Z preproprotein
[Homo sapiens]
Length = 303
Score = 328 bits (841), Expect = 2e-88
Identities = 163/307 (53%), Positives = 201/307 (65%), Gaps = 4/307 (1%)
Frame = +2
Query: 74 VLALALAAGTAHGKVVLR--ESTGRPSRYASTIVRHEDIPEL--ITTPRSHELISEKDLP 241
+L L L AG A G + R ++ RP +R + + L T PR HE +S DLP
Sbjct: 11 LLLLVLLAGAAQGGLYFRRGQTCYRP-------LRGDGLAPLGRSTYPRPHEYLSPADLP 63
Query: 242 REWDWRAVPSSANSDDRHNYLSIIRNQHIPKYCGSCWAHGASSSLADRMNIKMKGAWPGT 421
+ WDWR V D NY SI RNQHIP+YCGSCWAH ++S++ADR+NIK KGAWP T
Sbjct: 64 KSWDWRNV-------DGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPST 116
Query: 422 FLSVQNIIDCGGAGSCNGGDDRLVYVYGAKHGIPPDTCNLYVAANQKCHAMQQCFTCWPD 601
LSVQN+IDCG AGSC GG+D V+ Y +HGIP +TCN Y A +Q+C QC TC
Sbjct: 117 LLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEF 176
Query: 602 STCEPIYDYKRLTVSEHGRVRGRYQMKAEIYKRGPISCGIDATDQLETYTGGVYAERKSN 781
C I +Y V ++G + GR +M AEIY GPISCGI AT++L YTGG+YAE +
Sbjct: 177 KECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDT 236
Query: 782 PSINHVVSVVGWGVDPETDVEYWVIRNSWGEPWGESGFLKLVTSAYDDGNGNMYNLAIED 961
INHVVSV GWG+ T EYW++RNSWGEPWGE G+L++VTS Y DG G YNLAIE+
Sbjct: 237 TYINHVVSVAGWGISDGT--EYWIVRNSWGEPWGERGWLRIVTSTYKDGKGARYNLAIEE 294
Query: 962 DCNFGVP 982
C FG P
Sbjct: 295 HCTFGDP 301
>ref|NP_899159.1| cathepsin Y [Rattus norvegicus] gi|34978341|sp|Q9R1T3|CATZ_RAT
Cathepsin Z precursor (Cathepsin Y)
gi|28971937|dbj|BAA82844.2| cathepsin Y [Rattus
norvegicus]
Length = 306
Score = 328 bits (841), Expect = 2e-88
Identities = 159/309 (51%), Positives = 201/309 (64%), Gaps = 5/309 (1%)
Frame = +2
Query: 71 LVLALALAAGTAHGKVVLR--ESTGRPSRYASTIVRHEDIPELI---TTPRSHELISEKD 235
LVL + L AG A + R ++ RP H D L+ T PR HE +S D
Sbjct: 12 LVLLMLLLAGAARASLYFRPGQTCYRPL--------HRDHLALLGRRTYPRPHEYLSPAD 63
Query: 236 LPREWDWRAVPSSANSDDRHNYLSIIRNQHIPKYCGSCWAHGASSSLADRMNIKMKGAWP 415
LP+ WDWR V NY S+ RNQHIP+YCGSCWAHG++S+LADR+NIK KGAWP
Sbjct: 64 LPKNWDWRNVNGV-------NYASVTRNQHIPQYCGSCWAHGSTSALADRINIKRKGAWP 116
Query: 416 GTFLSVQNIIDCGGAGSCNGGDDRLVYVYGAKHGIPPDTCNLYVAANQKCHAMQQCFTCW 595
T LSVQN+IDCG AGSC GG+D V+ Y KHGIP +TCN Y A +Q+C QC TC
Sbjct: 117 STLLSVQNVIDCGNAGSCEGGNDLPVWEYAHKHGIPDETCNNYQAKDQECDKFNQCGTCT 176
Query: 596 PDSTCEPIYDYKRLTVSEHGRVRGRYQMKAEIYKRGPISCGIDATDQLETYTGGVYAERK 775
C I +Y V ++G + GR +M AEIY GPISCGI AT+++ YTGG+Y E +
Sbjct: 177 EFKECHTIQNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERMSNYTGGIYTEYQ 236
Query: 776 SNPSINHVVSVVGWGVDPETDVEYWVIRNSWGEPWGESGFLKLVTSAYDDGNGNMYNLAI 955
+ INH++SV GWGV + +EYW++RNSWGEPWGE G++++VTS Y G G+ YNLAI
Sbjct: 237 NQAIINHIISVAGWGVSND-GIEYWIVRNSWGEPWGERGWMRIVTSTYKGGTGSSYNLAI 295
Query: 956 EDDCNFGVP 982
E+ C FG P
Sbjct: 296 EEACTFGDP 304
>gb|AAC63141.1| preprocathepsin P [Homo sapiens]
Length = 293
Score = 328 bits (841), Expect = 2e-88
Identities = 163/307 (53%), Positives = 201/307 (65%), Gaps = 4/307 (1%)
Frame = +2
Query: 74 VLALALAAGTAHGKVVLR--ESTGRPSRYASTIVRHEDIPEL--ITTPRSHELISEKDLP 241
+L L L AG A G + R ++ RP +R + + L T PR HE +S DLP
Sbjct: 1 LLLLVLLAGAAQGGLYFRRGQTCYRP-------LRGDGLAPLGRSTYPRPHEYLSPADLP 53
Query: 242 REWDWRAVPSSANSDDRHNYLSIIRNQHIPKYCGSCWAHGASSSLADRMNIKMKGAWPGT 421
+ WDWR V D NY SI RNQHIP+YCGSCWAH ++S++ADR+NIK KGAWP T
Sbjct: 54 KSWDWRNV-------DGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPST 106
Query: 422 FLSVQNIIDCGGAGSCNGGDDRLVYVYGAKHGIPPDTCNLYVAANQKCHAMQQCFTCWPD 601
LSVQN+IDCG AGSC GG+D V+ Y +HGIP +TCN Y A +Q+C QC TC
Sbjct: 107 LLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEF 166
Query: 602 STCEPIYDYKRLTVSEHGRVRGRYQMKAEIYKRGPISCGIDATDQLETYTGGVYAERKSN 781
C I +Y V ++G + GR +M AEIY GPISCGI AT++L YTGG+YAE +
Sbjct: 167 KECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDT 226
Query: 782 PSINHVVSVVGWGVDPETDVEYWVIRNSWGEPWGESGFLKLVTSAYDDGNGNMYNLAIED 961
INHVVSV GWG+ T EYW++RNSWGEPWGE G+L++VTS Y DG G YNLAIE+
Sbjct: 227 TYINHVVSVAGWGISDGT--EYWIVRNSWGEPWGERGWLRIVTSTYKDGKGARYNLAIEE 284
Query: 962 DCNFGVP 982
C FG P
Sbjct: 285 HCTFGDP 291
