Nr search
BLASTX 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= KCC000518A_C01 KCC000518A_c01
(1015 letters)
Database: nr
1,537,769 sequences; 498,525,298 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
sp|Q39586|METE_CHLRE 5-methyltetrahydropteroyltriglutamate--homo... 571 e-163
ref|ZP_00073482.1| COG0620: Methionine synthase II (cobalamin-in... 243 7e-63
ref|NP_681881.1| 5-methyltetrahydropteroyltriglutamate--homocyst... 229 7e-59
ref|NP_215649.1| metE [Mycobacterium tuberculosis H37Rv] gi|1584... 176 7e-43
ref|ZP_00011939.1| COG0620: Methionine synthase II (cobalamin-in... 167 2e-40
>sp|Q39586|METE_CHLRE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
(Methionine synthase, vitamin-B12 independent isozyme)
(Cobalamin-independent methionine synthase)
gi|2129456|pir||S65083
5-methyltetrahydropteroyltriglutamate-homocysteine
S-methyltransferase (EC 2.1.1.14) - Chlamydomonas
reinhardtii gi|1017759|gb|AAC49178.1|
cobalamin-independent methionine synthase
gi|1587968|prf||2207381A Met synthase
Length = 814
Score = 571 bits (1471), Expect(2) = e-163
Identities = 287/294 (97%), Positives = 288/294 (97%)
Frame = +3
Query: 132 GNQRQLKFAMESYFKGDSGEAELLAVAHKVQSDAWALQKAAGIAVIGLDGTLYDQVLDTI 311
GNQRQLKFAMESYFKGDSGEAELLAVAHKVQSDAWALQKAAGIAVIGLDGTLYDQVLDTI
Sbjct: 13 GNQRQLKFAMESYFKGDSGEAELLAVAHKVQSDAWALQKAAGIAVIGLDGTLYDQVLDTI 72
Query: 312 TWLGAIPPRFKHLSGLQRYYAMARGGAALDMSKFFDTNYHYLVPELGPDVLGPATAAGAP 491
TWLGAIPPRFKHLSGLQRYYAMARGGAALDMSKFFDTNYHYLVPELGPDVLGPATA G P
Sbjct: 73 TWLGAIPPRFKHLSGLQRYYAMARGGAALDMSKFFDTNYHYLVPELGPDVLGPATA-GPP 131
Query: 492 LQPDFSGPLDKLARGQAVVGRERAVPILIGPVTFVSLSRGCELPLDQAVARLLPTYCALL 671
LQPDFSGPLDKLARGQAVVGR+ AVPILIGPVTFVSLSRGCELPLDQAVARLLPTYCALL
Sbjct: 132 LQPDFSGPLDKLARGQAVVGRDGAVPILIGPVTFVSLSRGCELPLDQAVARLLPTYCALL 191
Query: 672 QQLAAAGAPEVQLHEPVLATSEGAGMRAEFETAYAQMAQAAGSVPLHLVTYYDDLGAAYP 851
QQLAAAGAPEVQLHEPVLATSEG GM EFETAYAQMAQAAGSVPLHLVTYYDDLGAAYP
Sbjct: 192 QQLAAAGAPEVQLHEPVLATSEGTGMPTEFETAYAQMAQAAGSVPLHLVTYYDDLGAAYP 251
Query: 852 WAVQLPVAAVTLDFLGPPGAAVPSQTLALLQQHGFPADKRLGAGVVDGRSVWKD 1013
WAVQLPVAAVTLDFLGPPGAAVPSQTLALLQQHGFPADKRLGAGVVDGRSVWKD
Sbjct: 252 WAVQLPVAAVTLDFLGPPGAAVPSQTLALLQQHGFPADKRLGAGVVDGRSVWKD 305
Score = 27.7 bits (60), Expect(2) = e-163
Identities = 12/12 (100%), Positives = 12/12 (100%)
Frame = +2
Query: 95 MLSTTTIGFPRI 130
MLSTTTIGFPRI
Sbjct: 1 MLSTTTIGFPRI 12
>ref|ZP_00073482.1| COG0620: Methionine synthase II (cobalamin-independent)
[Trichodesmium erythraeum IMS101]
Length = 744
Score = 243 bits (619), Expect(2) = 7e-63
Identities = 129/297 (43%), Positives = 186/297 (62%), Gaps = 4/297 (1%)
Frame = +3
Query: 132 GNQRQLKFAMESYFKGDSGEAELLAVAHKVQSDAWALQKAAGIAVIGL-DGTLYDQVLDT 308
G R++K A+ES+++ ELL + +++ +W Q AGI IG+ D TLYDQ+LD
Sbjct: 14 GKNREVKKALESFWQQKISADELLKIVREIEEASWQTQTKAGIERIGIGDATLYDQILDW 73
Query: 309 ITWLGAIPPRFKHLSGLQRYYAMARGG---AALDMSKFFDTNYHYLVPELGPDVLGPATA 479
G IP RF+ L+ Y+AMARG AL+M+K+FDTNYHYLVPE+ PD+ A
Sbjct: 74 SFRFGIIPKRFQQFQNLECYFAMARGKDGILALEMTKWFDTNYHYLVPEITPDITPKA-- 131
Query: 480 AGAPLQPDFSGPLDKLARGQAVVGRERAVPILIGPVTFVSLSRGCELPLDQAVARLLPTY 659
DFS L+ + R + ++G+ AVPI+I P+TF+ LSR + D +A+LLP Y
Sbjct: 132 -------DFSDFLETVKRAKKIIGKS-AVPIIISPITFIRLSRLESVEFDNILAQLLPLY 183
Query: 660 CALLQQLAAAGAPEVQLHEPVLATSEGAGMRAEFETAYAQMAQAAGSVPLHLVTYYDDLG 839
LL +L G E+QLHEP L + + ++ +FE AYA++A+ + +HLVTY+DDLG
Sbjct: 184 SDLLTKLKKLGISEIQLHEPALVFGDSSNLKKQFEMAYAELAKV--GLNIHLVTYFDDLG 241
Query: 840 AAYPWAVQLPVAAVTLDFLGPPGAAVPSQTLALLQQHGFPADKRLGAGVVDGRSVWK 1010
YPW ++LPV +++LD Q L L++ +GFPADK LGAGVVD R++W+
Sbjct: 242 ETYPWVMKLPVTSISLDL-------TRGQNLELIKSYGFPADKTLGAGVVDARNIWR 291
Score = 21.6 bits (44), Expect(2) = 7e-63
Identities = 7/11 (63%), Positives = 11/11 (99%)
Frame = +2
Query: 98 LSTTTIGFPRI 130
+ST+T+G+PRI
Sbjct: 3 ISTSTLGYPRI 13
>ref|NP_681881.1| 5-methyltetrahydropteroyltriglutamate--homocyste ine
S-methyltransferase [Thermosynechococcus elongatus BP-1]
gi|30173040|sp|Q8DJY0|METE_SYNEL
5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase (Methionine synthase, vitamin-B12
independent isozyme) (Cobalamin-independent methionine
synthase) gi|22294814|dbj|BAC08643.1|
5-methyltetrahydropteroyltriglutamate--homocyste ine
S-methyltransferase [Thermosynechococcus elongatus BP-1]
Length = 758
Score = 229 bits (583), Expect = 7e-59
Identities = 129/298 (43%), Positives = 185/298 (61%), Gaps = 5/298 (1%)
Frame = +3
Query: 132 GNQRQLKFAMESYFKGDSGEAELLAVAHKVQSDAWALQKAAGIAVIGL-DGTLYDQVLDT 308
G R+LK A+E+++ LL A ++ W Q GI IG+ D +LYD VLD
Sbjct: 14 GKNRELKKALEAFWSNQLDAEALLKTAQDIELQNWQKQLEVGIDRIGIGDLSLYDSVLDW 73
Query: 309 ITWLGAIPPRFKHLSGLQRYYAMARGG---AALDMSKFFDTNYHYLVPELGPDVLGPATA 479
G IP R++ +GL++Y+AMARG AL+M+K+FDTNYHYLVPE+
Sbjct: 74 SIRFGIIPERYRSFTGLEQYFAMARGKDGIPALEMTKWFDTNYHYLVPEISE-------- 125
Query: 480 AGAPLQP-DFSGPLDKLARGQAVVGRERAVPILIGPVTFVSLSRGCELPLDQAVARLLPT 656
QP DFS L+ + R Q ++G +RAVPI++GP+T + LSR E L+QAV+ L
Sbjct: 126 ---AFQPTDFSDFLETVRRAQTLLG-DRAVPIVLGPLTLLRLSR-LETNLEQAVSYLRDR 180
Query: 657 YCALLQQLAAAGAPEVQLHEPVLATSEGAGMRAEFETAYAQMAQAAGSVPLHLVTYYDDL 836
Y LL++L G EVQ+HEP L E ++ +++ + + QA ++PLHLVTY+DDL
Sbjct: 181 YLILLRELKNLGVVEVQIHEPALVLEEADSFKSFYQSTFDTLRQA--NLPLHLVTYFDDL 238
Query: 837 GAAYPWAVQLPVAAVTLDFLGPPGAAVPSQTLALLQQHGFPADKRLGAGVVDGRSVWK 1010
GAA+PW ++LPV ++LDF LALL+++GFPADK+LG G++DGR++WK
Sbjct: 239 GAAWPWVMELPVTCISLDF-------TRGHNLALLKEYGFPADKQLGVGIIDGRNIWK 289
>ref|NP_215649.1| metE [Mycobacterium tuberculosis H37Rv] gi|15840571|ref|NP_335608.1|
5-methyltetrahydropteroyltriglutamate-homocysteine
methyltransferase [Mycobacterium tuberculosis CDC1551]
gi|31792327|ref|NP_854820.1| PROBABLE
5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE
METHYLTRANSFERASE METE (methionine synthase, vitamin-B12
independent isozyme) [Mycobacterium bovis subsp. bovis
AF2122/97] gi|3334257|sp|O06584|METE_MYCTU
5-methyltetrahydropteroyltriglutamate--homocysteine
methyltransferase (Methionine synthase, vitamin-B12
independent isozyme) (Cobalamin-independent methionine
synthase) gi|7433424|pir||F70539 probable
5-methyltetrahydropteroyltriglutamate-homocysteine
methyltransferase - Mycobacterium tuberculosis (strain
H37RV) gi|2117227|emb|CAB09044.1| metE [Mycobacterium
tuberculosis H37Rv] gi|13880750|gb|AAK45422.1|
5-methyltetrahydropteroyltriglutamate-homocysteine
methyltransferase [Mycobacterium tuberculosis CDC1551]
gi|31617915|emb|CAD94025.1| PROBABLE
5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE
METHYLTRANSFERASE METE (methionine synthase, vitamin-B12
independent isozyme) [Mycobacterium bovis subsp. bovis
AF2122/97]
Length = 759
Score = 176 bits (445), Expect = 7e-43
Identities = 121/321 (37%), Positives = 171/321 (52%), Gaps = 14/321 (4%)
Frame = +3
Query: 90 RPCSRRPPSASLAS----GNQRQLKFAMESYFKGDSGEAELLAVAHKVQSDAWALQKAAG 257
+P R+P +A++ G +R+LK A E Y+ G + +EL AVA ++ D W+ AAG
Sbjct: 3 QPVRRQPFTATITGSPRIGPRRELKRATEGYWAGRTSRSELEAVAATLRRDTWSALAAAG 62
Query: 258 IAVIGLDG-TLYDQVLDTITWLGAIPPRFKHLS-GLQRYYAMARGG---AALDMSKFFDT 422
+ + ++ + YDQ+LDT LGA+PPR +S GL RY+A ARG A L+M+K+FDT
Sbjct: 63 LDSVPVNTFSYYDQMLDTAVLLGALPPRVSPVSDGLDRYFAAARGTDQIAPLEMTKWFDT 122
Query: 423 NYHYLVPELGPDVLGPATAAGAPLQPDFSGPLDKLARGQAVVGRERAVPILIGPVTFVSL 602
NYHYLVPE+GP L P K A GQ + R P++IGP+TF+ L
Sbjct: 123 NYHYLVPEIGPSTT-------FTLHPGKVLAELKEALGQGIPAR----PVIIGPITFLLL 171
Query: 603 SR---GCELPLDQAVARLLPTYCALLQQLAAAGAPEVQLHEPVLATSEGAGMRAEFETAY 773
S+ G P+++ + L+P Y LL LA GA VQ EP L T A E Y
Sbjct: 172 SKAVDGAGAPIER-LEELVPVYSELLSLLADGGAQWVQFDEPALVTDLSPDAPALAEAVY 230
Query: 774 AQMAQAAGSVPLHLVTYYDDLGAAYPWAVQLPVAAVTLDFLGPPGAAVPSQTLALLQQHG 953
+ + +++ TY+ D GAA P + PV A+ +D + +V G
Sbjct: 231 TALCSVSNRPAIYVATYFGDPGAALPALARTPVEAIGVDLVAGADTSVA----------G 280
Query: 954 FP--ADKRLGAGVVDGRSVWK 1010
P A K L AGVVDGR+VW+
Sbjct: 281 VPELAGKTLVAGVVDGRNVWR 301
>ref|ZP_00011939.1| COG0620: Methionine synthase II (cobalamin-independent)
[Rhodopseudomonas palustris]
Length = 788
Score = 167 bits (424), Expect = 2e-40
Identities = 118/322 (36%), Positives = 168/322 (51%), Gaps = 29/322 (9%)
Frame = +3
Query: 132 GNQRQLKFAMESYFKGDSGEAELLAVAHKVQSDAWALQKAAGIAVI-GLDGTLYDQVLDT 308
G +R+LK A+ES++ G S EA+LL VA +++ WA Q A G++VI D +LYDQVLDT
Sbjct: 21 GPRRELKSALESFWAGKSTEADLLKVAAALRAANWARQSARGVSVIPSNDFSLYDQVLDT 80
Query: 309 ITWLGAIPPRFKHLSG---LQRYYAMARGGAA-----------------------LDMSK 410
+GAIP + G L Y+AMARG A +M+K
Sbjct: 81 SVMVGAIPEIYGWRGGPVSLATYFAMARGTQAEIAGHGCANGHHHGDSTPQGVPAQEMTK 140
Query: 411 FFDTNYHYLVPELGPDVLGPATAAGAPLQPDFSGPLDKLARGQAVVGRERAVPILIGPVT 590
+FDTNYHY+VPE +AG Q PL++ +A+ R P+L+GPVT
Sbjct: 141 WFDTNYHYMVPEF---------SAGQSFQLASVKPLEEYREAKALGYDTR--PVLLGPVT 189
Query: 591 FVSLSRGCELPLD--QAVARLLPTYCALLQQLAAAGAPEVQLHEPVLATSEGAGMRAEFE 764
++ L + + LD + +L+P Y +L +LAAAGA VQL EP L R F
Sbjct: 190 YLKLGKSADAGLDVLSLLPKLVPVYIEILGRLAAAGAKWVQLDEPALVLDLDDRERLAFR 249
Query: 765 TAYAQMAQAAGSVPLHLVTYYDDLGAAYPWAVQLPVAAVTLDFLGPPGAAVPSQTLALLQ 944
AY Q+A+ + + L TY+ LG A+ LP+A + LD + P Q A++
Sbjct: 250 DAYGQIARELPHLDIMLTTYFGGLGDNLDTALALPIAGLHLDLV-----RAPKQINAVIA 304
Query: 945 QHGFPADKRLGAGVVDGRSVWK 1010
+ P D L GVVDGR++W+
Sbjct: 305 KG--PKDLVLSLGVVDGRNIWR 324
