# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sh07415.fasta.huge -Q ../query/FLJ00319.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00319, 456 aa vs ./tmplib.10216 library 2210538 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 3.3888+/-0.00365; mu= 23.2346+/- 0.247 mean_var=78.8728+/-17.276, 0's: 0 Z-trim: 3 B-trim: 0 in 0/40 Lambda= 0.144414 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 37, opt: 25, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA1001 ( 551 res) hk09652 ( 551) 264 64.5 2.4e-11 KIAA1077 ( 818 res) hj06803 ( 818) 111 32.9 0.11 KIAA0253 ( 708 res) ha07036 ( 708) 99 30.3 0.61 KIAA1247 ( 885 res) pj01452 ( 885) 95 29.6 1.2 KIAA0582 ( 760 res) fh15957 ( 760) 91 28.7 2 KIAA0879 ( 461 res) hk07371 ( 461) 83 26.6 5 KIAA1672 ( 395 res) hj02515 ( 395) 82 26.3 5.3 KIAA1907 ( 1737 res) ah00504 (1737) 86 28.2 6.1 FLJ00178 ( 249 res) sj01102 ( 249) 78 25.1 7.5 KIAA0337 ( 1609 res) hg01226 (1609) 84 27.8 7.9 FLJ00121 ( 448 res) sh00381 ( 448) 79 25.8 8.7 KIAA1813 ( 673 res) ph00819b ( 673) 80 26.3 9.2 KIAA0250 ( 1122 res) ha02790 (1122) 81 26.9 10 KIAA0076 ( 1701 res) ha00936 (1701) 82 27.4 11 KIAA0755 ( 1093 res) hk04532 (1093) 80 26.6 12 KIAA0741 ( 1222 res) hk04024 (1222) 80 26.7 12 KIAA0082 ( 882 res) ha02350 ( 882) 78 26.1 14 KIAA0089 ( 411 res) ha03662 ( 411) 75 24.9 15 KIAA1625 ( 859 res) hh15184 ( 859) 77 25.8 16 KIAA1546 ( 684 res) fh12289 ( 684) 76 25.5 17 FLJ00048 ( 146 res) as00048 ( 146) 70 23.1 18 KIAA1800 ( 736 res) fj21226 ( 736) 75 25.3 20 KIAA0392 ( 550 res) hh00034 ( 550) 74 24.9 20 KIAA0681 ( 538 res) hk02748 ( 538) 73 24.7 23 KIAA1122 ( 1048 res) hj01698 (1048) 75 25.6 24 KIAA0370 ( 1132 res) sj06874 (1132) 75 25.6 24 KIAA1783 ( 1560 res) fg01285 (1560) 76 26.1 25 FLJ00131 ( 173 res) sh01962 ( 173) 68 22.8 27 KIAA0875 ( 621 res) hk07350 ( 621) 72 24.6 28 FLJ00129 ( 668 res) sh01893 ( 668) 72 24.6 29 FLJ00142 ( 674 res) sh04107 ( 674) 72 24.6 29 FLJ00154 ( 1471 res) sh06142 (1471) 74 25.6 32 FLJ00377 ( 190 res) sh08074 ( 190) 67 22.6 32 KIAA0212 ( 666 res) ha02602 ( 666) 71 24.4 33 KIAA1951 ( 679 res) fj05532 ( 679) 71 24.4 34 FLJ00275 ( 382 res) sh00566 ( 382) 69 23.6 34 KIAA0529 ( 952 res) hg02898s1 ( 952) 72 24.9 34 KIAA1738 ( 1127 res) pj00192s1 (1127) 72 25.0 37 KIAA1846 ( 354 res) fg06344s1 ( 354) 68 23.3 38 FLJ00173 ( 1269 res) sj00667 (1269) 72 25.1 39 KIAA1224 ( 997 res) fh02652 ( 997) 71 24.7 41 KIAA0963 ( 1391 res) hj05936 (1391) 72 25.2 41 FLJ00140 ( 579 res) sh03502 ( 579) 69 23.9 41 KIAA0054 ( 1943 res) ha00503s1 (1943) 73 25.6 42 KIAA1485 ( 1104 res) fj07037 (1104) 71 24.8 43 KIAA1683 ( 832 res) fh24307 ( 832) 70 24.4 43 KIAA1963 ( 488 res) ph00179 ( 488) 68 23.6 44 KIAA0804 ( 1211 res) hk01186(revised) (1211) 71 24.8 45 KIAA0249 ( 902 res) ha07006 ( 902) 70 24.4 45 KIAA1297 ( 2242 res) fg03883 (2242) 73 25.7 45 >>KIAA1001 ( 551 res) hk09652 (551 aa) initn: 679 init1: 219 opt: 264 Z-score: 297.0 bits: 64.5 E(): 2.4e-11 Smith-Waterman score: 649; 35.529% identity (59.529% similar) in 425 aa overlap (16-406:113-512) 10 20 30 40 FLJ003 ATPFLSSFCFCHLHIARAALLTGRLPIRNGFYTTNAHARNAYTPQ .::.:::::: .::: .:: . . KIAA10 ETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGV------TRNFAVTS 90 100 110 120 130 50 60 70 80 90 100 FLJ003 EIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQFHPLKHGFDEWFGSPNCH-FG-- :::.: .: : :.:..::::. :.:::::::. ..:: .::: .:: : : .: KIAA10 --VGGLPLNETTLAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCT 140 150 160 170 180 190 110 120 130 140 FLJ003 --P-YDNKARPNIP--------VYRD--WEMVGRYYE-----EFPINLKTGEANLTQIYL : :.. : : . :: ... :: : :.:: ..:.: : KIAA10 DTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNL----SSLAQKYA 200 210 220 230 240 250 150 160 170 180 190 200 FLJ003 QEALDFIKRQARH-HPFFLYWAVDATHAPVYASKPFLGTSQRGR--YGDAVREIDDSIGK ..: .::.: . .::.:: :. :.:. ... : .. ::: :: .. :.:. .:. KIAA10 EKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQ--LPAAPRGRSLYGAGLWEMDSLVGQ 260 270 280 290 300 210 220 230 240 250 FLJ003 ILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLC----------GKQTTFEGG : . . : : .:::..::.::: . : .:: ::: .::::.::: KIAA10 IKDKV-DHTVKENTFLWFTGDNGP-WAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGG 310 320 330 340 350 360 260 270 280 290 300 310 FLJ003 MREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRL : ::::.:::.: .. .: : :..:.: : .::: . :. : .::... .:. :: KIAA10 HRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLF-GRS 370 380 390 400 410 420 320 330 340 350 360 370 FLJ003 MDRPIFYYRGDTLMAATLGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTK . .. .. :. .: . : : .. .. .: : .:. : : KIAA10 QPGHRVLFHPNSGAAGEFGALQ------TVRLERYKAFYITGGARACDGSTGPELQ-H-K 430 440 450 460 470 380 390 400 410 420 430 FLJ003 LPLIFHLGRDPGERFPLSFASAEYQEALSRITSVVQQHQEALVPAQPQLNVCNWAVMNWA .::::.: : .: :: ..:::: .: .. .:. KIAA10 FPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADVLQDIANDNISSPDYTQDPSVTP 480 490 500 510 520 530 440 450 FLJ003 PPGCEKLGKCLTPPESIPKKCLWSH KIAA10 CCNPYQIACRCQAA 540 550 >>KIAA1077 ( 818 res) hj06803 (818 aa) initn: 40 init1: 40 opt: 111 Z-score: 123.2 bits: 32.9 E(): 0.11 Smith-Waterman score: 180; 22.741% identity (50.156% similar) in 321 aa overlap (16-306:37-336) 10 20 30 40 FLJ003 ATPFLSSFCFCHLHIARAALLTGRLPIRNGFYTTNAHARNAYTPQ .:...:::. .. ::.: .: .:. KIAA10 LQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNN---ENCSSPS 10 20 30 40 50 60 50 60 70 80 90 100 FLJ003 EIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQFHPLKHGFDEWFGS-PNCHFGPY . : . . :...:: . . ::. . .. : :. ::.: : .: : KIAA10 WQAMHEP---RTFAVYLNNTGYRTAFFGKYLNEYNGSYIP--PGWREWLGLIKNSRFYNY 70 80 90 100 110 110 120 130 140 150 FLJ003 DNKARPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQ-IYLQEALDFIKRQARHH----- . : .: . .... :. .. : . . .... .: .. . .. .: : KIAA10 -TVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDS 120 130 140 150 160 170 160 170 180 190 FLJ003 -PFF--LYWAVDATHAPVYASKP--------------------FLGTSQRGRYGDAVREI : : :: .. .: : : : . :: : ... . KIAA10 APQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRL-QTLMSV 180 190 200 210 220 230 200 210 220 230 240 250 FLJ003 DDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREP :::. .. ..: . .::....:.:.: . :. : .. ::. .. .: : KIAA10 DDSVERLYNMLVETGELENTYIIYTADHGYHI-------GQFG-LVKGKSMPYDFDIRVP 240 250 260 270 280 260 270 280 290 300 310 FLJ003 ALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRP . :. : :.. :. .:: : : .::: : : .:: ..: : KIAA10 FFIRGPS-VEPGSIVPQIVLNIDLAPTILDIAGLDTPPD--VDGKSVLKLLDPEKPGNRF 290 300 310 320 330 340 320 330 340 350 360 370 FLJ003 IFYYRGDTLMAATLGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPLI KIAA10 RTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARYQTACEQPG 350 360 370 380 390 400 >>KIAA0253 ( 708 res) ha07036 (708 aa) initn: 46 init1: 46 opt: 99 Z-score: 110.3 bits: 30.3 E(): 0.61 Smith-Waterman score: 99; 30.172% identity (50.000% similar) in 116 aa overlap (53-161:98-209) 30 40 50 60 70 80 FLJ003 GRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKK-AGYVSKIVGKWHLGHRP .:... .:..: : .:.:.: .: KIAA02 DTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKP 70 80 90 100 110 120 90 100 110 120 130 FLJ003 QFHPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRD--WEMVGR--YYEEF--PINLKTG . : ::. :: :: :.:. :.. :. :. .: ::.: :: : KIAA02 S--P-ASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLED 130 140 150 160 170 180 140 150 160 170 180 190 FLJ003 EANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFLGTSQRGRYGDAVREI : : :.. : : : : : KIAA02 E-NETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINP 190 200 210 220 230 240 >>KIAA1247 ( 885 res) pj01452 (885 aa) initn: 145 init1: 76 opt: 95 Z-score: 104.9 bits: 29.6 E(): 1.2 Smith-Waterman score: 159; 28.571% identity (53.896% similar) in 154 aa overlap (163-314:274-413) 140 150 160 170 180 190 FLJ003 KTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDAT--HAPVYASKPFLGTSQRGRYGD .: . : :.. : . :: : . KIAA12 EDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHME--FTNMLQRKRL-Q 250 260 270 280 290 300 200 210 220 230 240 250 FLJ003 AVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTFEG .. .:::. : ..: . :::.. .:.:.: . :. : .. ::. .: KIAA12 TLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHI-------GQFG-LVKGKSMPYEF 310 320 330 340 350 260 270 280 290 300 310 FLJ003 GMREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGR .: : . : .: :: .. .. .:: : : .::: :.: .:: ..: : : KIAA12 DIRVPFYVRGP-NVEAGCLNPHIVLNIDLAPTILDIAGLDIPAD--MDGKSILKLLDTER 360 370 380 390 400 320 330 340 350 360 370 FLJ003 LMDRPIFYYRGDTLMAATLGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHT ..: KIAA12 PVNRFHLKKKMRVWRDSFLVERGKLLHKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTA 410 420 430 440 450 460 >>KIAA0582 ( 760 res) fh15957 (760 aa) initn: 91 init1: 60 opt: 91 Z-score: 101.0 bits: 28.7 E(): 2 Smith-Waterman score: 92; 26.923% identity (46.154% similar) in 130 aa overlap (156-285:291-406) 130 140 150 160 170 180 FLJ003 EEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFLGTSQR :: :. : : . .: . KIAA05 DASGLGRRRLSFQAEYWACVLPDSLPPSPDRHSPL---WN------PNKEYEDLLDYTYP 270 280 290 300 310 190 200 210 220 230 240 FLJ003 GRYGDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQ : : . . :: .::: : ..: : . :. ...: . . : : . KIAA05 LRPGPQLPKHLDSRVPADPVLQDSGVDLDSF----SVSPASTLKSPTNVSPNCPPAEATA 320 330 340 350 360 250 260 270 280 290 300 FLJ003 TTFEGGMREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPT : .: :::.: ::..: : . :.: .: .: : KIAA05 LPF-SGPREPSLKQWPSRVPQKQGGMGLASWSQLASTPRAPGSRDARWERREPALRGAKD 370 380 390 400 410 420 310 320 330 340 350 360 FLJ003 LLQGRLMDRPIFYYRGDTLMAATLGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHN KIAA05 RLTIGKHLDMGSPQLRTRDRGWPSPRPEREKRTSQSARRPTCTESRWKSEEEVESDDEYL 430 440 450 460 470 480 >>KIAA0879 ( 461 res) hk07371 (461 aa) initn: 81 init1: 81 opt: 83 Z-score: 93.9 bits: 26.6 E(): 5 Smith-Waterman score: 83; 31.746% identity (60.317% similar) in 63 aa overlap (162-224:191-247) 140 150 160 170 180 190 FLJ003 LKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFLGTSQRGRYGDA ::: . : :: : .. .. . KIAA08 NYNSSVSFEERLNNITMWLNNSNPPVTFATLYW-----EEP-DASGHKYGPEDKENMSRV 170 180 190 200 210 200 210 220 230 240 250 FLJ003 VREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGG ...::: :: ... :. : . .: :..:::.: KIAA08 LKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYTLIDLS 220 230 240 250 260 270 260 270 280 290 300 310 FLJ003 MREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRL KIAA08 PVAAILPKINRTEVYNKLKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWTIVL 280 290 300 310 320 330 >>KIAA1672 ( 395 res) hj02515 (395 aa) initn: 61 init1: 61 opt: 82 Z-score: 93.4 bits: 26.3 E(): 5.3 Smith-Waterman score: 82; 36.957% identity (63.043% similar) in 46 aa overlap (379-421:183-228) 350 360 370 380 390 400 FLJ003 GIDFCPGQNVSGVTTHNLEDHTKLPLIFHLGRDPGER---FPLSFASAEYQEALSRITSV : .: :. .:..::. . :::. .: : KIAA16 HLLNSWGVSRHDNAINYLDFLRAVENSKSTGAQPKEKEESMPINFATLNPQEAVRKIQEV 160 170 180 190 200 210 410 420 430 440 450 FLJ003 VQQHQEALVPAQPQLNVCNWAVMNWAPPGCEKLGKCLTPPESIPKKCLWSH :.. : :: : :. KIAA16 VESSQLALSTAFSALDKEDTGFVKATEFGQVLKDFCYKLTDNQYHYFLRKLRIHLTPYIN 220 230 240 250 260 270 >>KIAA1907 ( 1737 res) ah00504 (1737 aa) initn: 79 init1: 79 opt: 86 Z-score: 92.2 bits: 28.2 E(): 6.1 Smith-Waterman score: 87; 31.429% identity (57.143% similar) in 35 aa overlap (418-452:385-419) 390 400 410 420 430 440 FLJ003 LSFASAEYQEALSRITSVVQQHQEALVPAQPQLNVCNWAVMNWAPPGCEKLGKCLTPPES : ..:. . . : ::.. :.:: :: KIAA19 RCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEF 360 370 380 390 400 410 450 FLJ003 IPKKCLWSH .: KIAA19 AGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGF 420 430 440 450 460 470 >>FLJ00178 ( 249 res) sj01102 (249 aa) initn: 66 init1: 66 opt: 78 Z-score: 90.6 bits: 25.1 E(): 7.5 Smith-Waterman score: 78; 37.500% identity (59.375% similar) in 32 aa overlap (224-255:6-37) 200 210 220 230 240 250 FLJ003 EIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMR ::: .. : ::: : :: .. . . :. FLJ001 HVDLGGAARVGQPGLGGSPGTQLCPRRLSTPSPMQ 10 20 30 260 270 280 290 300 310 FLJ003 EPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMD : FLJ001 PPPDEARRDMAGDTQWSRPECQAWTGTLLLGTCLLYCARSSMPICTVSMSQDFGWNKKEA 40 50 60 70 80 90 >>KIAA0337 ( 1609 res) hg01226 (1609 aa) initn: 42 init1: 42 opt: 84 Z-score: 90.2 bits: 27.8 E(): 7.9 Smith-Waterman score: 84; 28.788% identity (54.545% similar) in 66 aa overlap (358-420:766-831) 330 340 350 360 370 380 FLJ003 TLGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPLIFHLGRDP---GE :. . :. ::: ::... :. .: KIAA03 EQSMRENKEKQALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAE 740 750 760 770 780 790 390 400 410 420 430 440 FLJ003 RFPLSFASAEYQEALSRITSVVQQHQEALVPAQPQLNVCNWAVMNWAPPGCEKLGKCLTP :. . ::: : .:. . .. : :.. : : KIAA03 RINKGVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLF 800 810 820 830 840 850 450 FLJ003 PESIPKKCLWSH KIAA03 LFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATN 860 870 880 890 900 910 456 residues in 1 query sequences 2210538 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 10:51:43 2009 done: Fri Feb 27 10:51:43 2009 Total Scan time: 0.540 Total Display time: 0.100 Function used was FASTA [version 34.26.5 April 26, 2007]