hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/shimazu/full/sh/sh04009/interpro/cnk_1/seq.in
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Query:  sh04009  527

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGEF   Guanine nucleotide exchange factor for Rho/R   205.4    5.1e-57   1
SH3      Src homology 3 domains                          66.7    2.8e-15   1
PH       Pleckstrin homology domain.                     58.0    1.3e-12   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
SH3        1/1      25    80 ..     1    58 []    66.7  2.8e-15
RhoGEF     1/1     119   298 ..     1   211 []   205.4  5.1e-57
PH         1/1     331   438 ..     1    82 []    58.0  1.3e-12

Alignments of top-scoring domains:
SH3: domain 1 of 1, from 25 to 80: score 66.7, E = 2.8e-15
                   *->eyvvAlYDyeaqnedELsFkkGDiitvleksddgWweGelnrtGkeG
                      + + Al+D+   +++EL Fk+GD+i+vle s+ +Ww+G+     ke 
     sh04009    25    VCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSE--DKEA 69   

                   lfPsnYVeeie<-*
                   +fP+++V++     
     sh04009    70 WFPASFVRLRV    80   

RhoGEF: domain 1 of 1, from 119 to 298: score 205.4, E = 5.1e-57
                   *->vlkELlqTErnYVrdLkilvevflkpLkkeakssllpllspdevktl
                      v++E+++TEr Y+++L+ + e+++++++k        +++  ++ t+
     sh04009   119    VIREIMDTERVYIKHLRDICEGYIRQCRKHTG-----MFTVAQLATI 160  

                   FgpNieeiyefHrrFLdeLeerveewllskdlKsernsviedsgerigdv
                   Fg Nie+iy+f+r+FL++Le+  ++ +              ++  +ig++
     sh04009   161 FG-NIEDIYKFQRKFLKDLEKQYNKEE--------------PHLSEIGSC 195  

                   FlklfsaeeffkiYseYcsnhpdalellkkLmkkkknpaFqkflkeiesk
                   Fl++   +e f iYseYc+nhp a   l+ Lm   k+ ++++f++ + + 
     sh04009   196 FLQN---QEGFAIYSEYCNNHPGACLELANLM---KQGKYRHFFEACRLL 239  

                   pncrsksearltLeslLikPvQRltkYpLLLkellkhtppdhedredLkk
                   ++++     +  ++ +L++PvQ ++kYpL L ellk+t+ +h d+ ++k 
     sh04009   240 QQMI-----DIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKA 284  

                   AleaikelasqvNe<-*
                   A+ea+k++a  +Ne   
     sh04009   285 AYEAMKNVACLINE    298  

PH: domain 1 of 1, from 331 to 438: score 58.0, E = 1.3e-12
                   *->vikeGwLlkks.k.swkkryfvLfngvLlyyksk.......kpkgsi
                      +i++G L+k ++ ++ ++r f+Lf+++L+ +k++  +++   +kg++
     sh04009   331    LIHSGELTKITkQgKSQQRTFFLFDHQLVSCKKDllrrdmlYYKGRL 377  

                   pLsgcsvre.p.............cFeivt.dr..tlllqAeseeereeW
                   +++++++++  ++++++ + + +++F++v+++ ++++l++A+ +e++ +W
     sh04009   378 DMDEMELVDlGdgrdkdcnlsvknAFKLVSrTTdeVYLFCAKKQEDKARW 427  

                   vealqsaiaka<-*
                   ++a  +  ++    
     sh04009   428 LQACADERRRV    438  

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