hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/shimazu/full/sh/sh04009/interpro/cnk_1/seq.in
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Query:  sh04009  527

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGEF   RhoGEF domain                                  147.2      3e-40   1
PH       PH domain                                       57.8    2.3e-13   1
SH3_1    SH3 domain                                      51.0    2.5e-11   1
SH3_2    Variant SH3 domain                              29.5    7.7e-05   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
SH3_1      1/1      25    79 ..     1    58 []    51.0  2.5e-11
SH3_2      1/1      26    79 ..     1    69 []    29.5  7.7e-05
RhoGEF     1/1     119   298 ..     1   207 []   147.2    3e-40
PH         1/1     331   436 ..     1    92 []    57.8  2.3e-13

Alignments of top-scoring domains:
SH3_1: domain 1 of 1, from 25 to 79: score 51.0, E = 2.5e-11
                   *->kkvvALYDYearesdELsFkkGDvitvleksddgWWkgrlkgtgGke
                        + AL D + ++++EL Fk GDvi+vle s+ +WW gr+    +ke
     sh04009    25    VCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSE---DKE 68   

                   GliPsNYVepv<-*
                    ++P+++V++    
     sh04009    69 AWFPASFVRLR    79   

SH3_2: domain 1 of 1, from 26 to 79: score 29.5, E = 7.7e-05
                   *->yvrairdyvaAtdenenleeeLslkkGdvvkVldvggskdddgwwlg
                       + a+ d+v   d +e     L +k+Gdv++Vl    + ++ +ww+g
     sh04009    26    CAEALWDHVT-MDDQE-----LGFKAGDVIQVL----EASNKDWWWG 62   

                   es.geEmaGrrmGlvPssaveel<-*
                   +s++    +++  ++P+s+v+     
     sh04009    63 RSeD----KEA--WFPASFVRLR    79   

RhoGEF: domain 1 of 1, from 119 to 298: score 147.2, E = 3e-40
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskpvltpddietiF
                      v++E++ TE+ Y+++L+++  +y ++ r+        +t  ++ tiF
     sh04009   119    VIREIMDTERVYIKHLRDICEGYIRQCRKHT----GMFTVAQLATIF 161  

                   sNiediyefhreFLkssLearisssqfedlDekkiepsaqrlGdlFlklk
                   +Niediy+f+r FLk  Le+    +          ep+ + +G++Fl+  
     sh04009   162 GNIEDIYKFQRKFLK-DLEKQYNKE----------EPHLSEIGSCFLQN- 199  

                   epflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd
                    + +++Y eYc+n+p A   l+ l    + + F+e +  +++  +     
     sh04009   200 QEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQMID----- 244  

                   davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedqpdredLkkaldl
                         ++ +Ll Pvq i++YpL L eLLk+t    ++ d+ + k+a+++
     sh04009   245 ----IAIDGFLLTPVQKICKYPLQLAELLKYTTQ--EHGDYSNIKAAYEA 288  

                   lqdlaksiNe<-*
                   ++++a+ iNe   
     sh04009   289 MKNVACLINE    298  

PH: domain 1 of 1, from 331 to 436: score 57.8, E = 2.3e-13
                   *->vikeGwLlkkggkkswkkRyfvLfndvLlyykdkk.....kkpkgsi
                      +i++G+L+k ++ ++ ++R f+Lf+++L+ +k++  +++   +kg +
     sh04009   331    LIHSGELTKITKQGKSQQRTFFLFDHQLVSCKKDLlrrdmLYYKGRL 377  

                   pLsgiqvekvpdn.......krkncFeirt.dr.etlllqaeseeerkeW
                   ++++++++++ d+++++ +   kn+F++++++ +e++l++a+ +e++ +W
     sh04009   378 DMDEMELVDLGDGrdkdcnlSVKNAFKLVSrTTdEVYLFCAKKQEDKARW 427  

                   vkaiqsair<-*
                   ++a+ ++ r   
     sh04009   428 LQACADERR    436  

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