hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna/full/aisin/as00018/interpro/cnk_1/seq.in
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Query:  as00018  1430

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGEF   Guanine nucleotide exchange factor for Rho/R   186.1    3.4e-51   1
PH       Pleckstrin homology domain.                     41.2    1.4e-07   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RhoGEF     1/1     150   326 ..     1   211 []   186.1  3.4e-51
PH         1/1     352   457 ..     1    82 []    41.2  1.4e-07

Alignments of top-scoring domains:
RhoGEF: domain 1 of 1, from 150 to 326: score 186.1, E = 3.4e-51
                   *->vlkELlqTErnYVrdLkilvevflkpLkkeakssllpllspdevktl
                      v++E+++TEr+YVrdL+ +ve +l pL++ +    +  ls ++v tl
     as00018   150    VAREIVETERAYVRDLRSIVEDYLGPLLDGG----VLGLSVEQVGTL 192  

                   FgpNieeiyefHrrFLdeLeerveewllskdlKsernsviedsgerigdv
                   F  Nie+iyef++++L++Le  +                   s   i+ +
     as00018   193 FA-NIEDIYEFSSELLEDLENSS-------------------SAGGIAEC 222  

                   FlklfsaeeffkiYseYcsnhpdalellkkLmkkkknpaFqkflkeiesk
                   F++    +e+f+iY+ Yc n+p++l+ll++L     +p+ + +l+e++++
     as00018   223 FVQR---SEDFDIYTLYCMNYPSSLALLREL---SLSPPAALWLQERQAQ 266  

                   pncrsksearltLeslLikPvQRltkYpLLLkellkhtpp..dhedredL
                    +++      l+L+s+L+kPvQR++kY+LLL+el kh  ++++   re++
     as00018   267 LRHS------LPLQSFLLKPVQRILKYHLLLQELGKHWAEgpGTGGREMV 310  

                   kkAleaikelasqvNe<-*
                   ++A+ +++ +a ++N+   
     as00018   311 EEAIVSMTAVAWYIND    326  

PH: domain 1 of 1, from 352 to 457: score 41.2, E = 1.4e-07
                   *->vikeGwLlkks..........k.swkkryfvLfngvLlyyksk....
                      +   G L   +  +++++++++ +  +r ++Lf+++Ll  k ++ + 
     as00018   352    LSAFGELVLEGafrggggggpRlRGGERLLFLFSRMLLVAKRRgley 398  

                   kpkgsipLsgcsvre.p....cFeivt.dr...tlllqAeseeereeWve
                   ++kg i+  ++sv+e+p+++ +F+++  + +++++llqA+++ee++ W++
     as00018   399 TYKGHIFCCNLSVSEsPrdplGFKVSDlTIpkhRHLLQAKNQEEKRLWIH 448  

                   alqsaiaka<-*
                   +lq++  ++   
     as00018   449 CLQRLFFEN    457  

//