BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146571.7 + phase: 0 /pseudo
(2018 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DPOZ_HUMAN (O60673) DNA polymerase zeta catalytic subunit (EC 2.... 692 0.0
DPOZ_MOUSE (Q61493) DNA polymerase zeta catalytic subunit (EC 2.... 691 0.0
DPOZ_YEAST (P14284) DNA polymerase zeta catalytic subunit (EC 2.... 617 e-175
DPOD_ORYSA (Q9LRE6) DNA polymerase delta catalytic subunit (EC 2... 323 3e-87
DPOD_BOVIN (P28339) DNA polymerase delta catalytic subunit (EC 2... 317 2e-85
DPOD_MOUSE (P52431) DNA polymerase delta catalytic subunit (EC 2... 317 3e-85
DPOD_RAT (O54747) DNA polymerase delta catalytic subunit (EC 2.7... 316 5e-85
DPOD_MESAU (P97283) DNA polymerase delta catalytic subunit (EC 2... 316 5e-85
DPOD_HUMAN (P28340) DNA polymerase delta catalytic subunit (EC 2... 310 3e-83
DPOD_DROME (P54358) DNA polymerase delta catalytic subunit (EC 2... 310 3e-83
DPOD_PLAFK (P30315) DNA polymerase delta catalytic subunit (EC 2... 308 1e-82
DPOD_YEAST (P15436) DNA polymerase delta catalytic subunit (EC 2... 301 1e-80
DPOD_CANAL (P46588) DNA polymerase delta catalytic subunit (EC 2... 298 1e-79
DPOD_SOYBN (O48901) DNA polymerase delta catalytic subunit (EC 2... 293 3e-78
DPOD_SCHPO (P30316) DNA polymerase delta catalytic subunit (EC 2... 291 2e-77
DPOD_CAEEL (P90829) DNA polymerase delta catalytic subunit (EC 2... 290 3e-77
DPOD_ARATH (Q9LVN7) DNA polymerase delta catalytic subunit (EC 2... 283 3e-75
DPOL_EBV (P03198) DNA polymerase (EC 2.7.7.7) 184 3e-45
DPOL_RHCM6 (O71121) DNA polymerase (EC 2.7.7.7) 180 4e-44
DPOL_SHV21 (P24907) DNA polymerase (EC 2.7.7.7) 179 5e-44
>DPOZ_HUMAN (O60673) DNA polymerase zeta catalytic subunit (EC
2.7.7.7) (hREV3)
Length = 3130
Score = 692 bits (1785), Expect = 0.0
Identities = 398/946 (42%), Positives = 558/946 (58%), Gaps = 66/946 (6%)
Query: 1078 EPGAKDKDISKCASGPTLRPELHQDTEKKLPCINEGQTERIKAHMDHSQDISQISGPGEK 1137
EP + K ++ TLR L + + +N Q E SQI GP
Sbjct: 2225 EPKTQKLSNKKGSNTDTLRRVLLTQAKNQFAAVNTPQKET-----------SQIDGPSLN 2273
Query: 1138 SSFTPLSQIGFQDPASAGHG-QQLALLSIEVLAESRGDLLPDPQFDAVNIVALGFQKDCD 1196
+++ I A A H Q L L+S+E+ A +R DL PDP+FD + + D
Sbjct: 2274 NTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLEPDPEFDPICALFYCISSDTP 2333
Query: 1197 AT-------VEVLVL-----LHSKFVPCQRSL---DGLSDCKVLNFTDEKHLLKEFTKIV 1241
V+V+ + S+ + Q L G++ +V DEK L E I+
Sbjct: 2334 LPDTEKTELTGVIVIDKDKTVFSQDIRYQTPLLIRSGITGLEVTYAADEKALFHEIANII 2393
Query: 1242 SSSDPDILMGWEIQGSSLGFLAERASHLGFGLLNDLSRTPSNSWINSQDIKTSEKSILEP 1301
DPDIL+G+EIQ S G+L +RA+ L L +SR P D K + E
Sbjct: 2394 KRYDPDILLGYEIQMHSWGYLLQRAAALSIDLCRMISRVP--------DDKIENRFAAE- 2444
Query: 1302 DIPDTTSLDCCARESSIIEDEWGRTHASGVHVGGRIVLNLWRLIRGEVKLNLYSVEAVAE 1361
DE+G S +++ GRI LNLWR++R EV L Y+ E V+
Sbjct: 2445 ------------------RDEYGSYTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSF 2486
Query: 1362 AVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYIVDRAKLNLEILNQLDMVNRTSELARV 1421
VL ++ P VL+ WF R++ + + V R + NL++L QLD++ +TSE+AR+
Sbjct: 2487 HVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARL 2546
Query: 1422 FGIDFFSVLSRGSQYRVESMFLRLAHTQNYVAISPGNQQVASQPAMECLPLVMEPESGFY 1481
FGI F VL+RGSQYRVESM LR+A NY+ ++P QQ + A +C+PL+MEPES FY
Sbjct: 2547 FGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFY 2606
Query: 1482 SDPVVVLDFQSLYPSMIIAYNLCFCTCLGKVV---PSKTNTLGVSPFVPEQHILQDLKDQ 1538
S+ V+VLDFQSLYPS++IAYN CF TCLG V G + +L ++
Sbjct: 2607 SNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQVRHD 2666
Query: 1539 ILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQAMKKLSPSEQVLQRIFNARQLALK 1598
I ++PNGV FV +R+GVLPR+LEEIL TR MVKQ+MK ++ L R+ +ARQL LK
Sbjct: 2667 ITVSPNGVAFVKPSVRKGVLPRMLEEILKTRFMVKQSMKAYK-QDRALSRMLDARQLGLK 2725
Query: 1599 LISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTLEKAISFVNLHEKWNAKVIYGDTDSM 1658
LI+NVT+GYT+A FSGRMPC E+ DSIV R TLE+AI VN +KW A+V+YGDTDSM
Sbjct: 2726 LIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSM 2785
Query: 1659 FVLLKGRTAKEAFQIGSEIASAITAMNPSPVTLKMEKVYHPCFLITKKRYVGYSYENPNQ 1718
FVLLKG T +++F+IG EIA A+TA NP PV LK EKVY PC L TKKRYVGY YE +Q
Sbjct: 2786 FVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQ 2845
Query: 1719 IEPVFDAKGIETVRRDTCEAVAKIMEQSLRLFFEHQSLLEVKTYLQRQWKRILSGRVSLK 1778
+PVFDAKGIETVRRD+C AV+KI+E+SL+L FE + + +K Y+QRQ ++L G+ S++
Sbjct: 2846 KDPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLLEGKASIQ 2905
Query: 1779 DFIFAKEVRLGTYSARISSLPPAAIVATKAMRVDRRAEPRYAERIPYVVIHGEPGARLVD 1838
DFIFAKE R G++S + + PA + K + DRR+EP+ ER+PYV+I+G PG L+
Sbjct: 2906 DFIFAKEYR-GSFSYKPGACVPALELTRKMLTYDRRSEPQVGERVPYVIIYGTPGVPLIQ 2964
Query: 1839 MVVDPLEVLAIDSPFRINDLYYINKQIIPALQRVFGLVGADLNQWFAEMPRPVREASVKH 1898
+V P+EVL D R+N YYI KQI+P L R+F L+G D+ W+ E+PR + +A+
Sbjct: 2965 LVRRPVEVLQ-DPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYHELPR-IHKATSSS 3022
Query: 1899 AFTPNFQRTRIDYYYLSKHCVLCGGLVQASARLCSQCSENEVAAATAVIGKTAKLEQEMQ 1958
P ++ I Y+ + HC +C L Q +CS+C A + + +LE++ +
Sbjct: 3023 RSEPEGRKGTISQYFTTLHCPVCDDLTQHG--ICSKCRSQPQHVAVILNQEIRELERQQE 3080
Query: 1959 HLVSICQHCGGGDRLLESGVKCTSISCLVFYERRKVQKELLAATHV 2004
LV IC++C G + + C S++C V ++ +V +EL A ++
Sbjct: 3081 QLVKICKNCTG---CFDRHIPCVSLNCPVLFKLSRVNRELSKAPYL 3123
Score = 189 bits (480), Expect = 7e-47
Identities = 120/346 (34%), Positives = 184/346 (52%), Gaps = 30/346 (8%)
Query: 10 VFSVRIVSVDHYMASPIPSIDISHSTFHRGKVNEVPVIRVYGSTPAGQKTCLHIHGALPY 69
+FSVRIV+ D+YMASP+ +D S + V +VPV+RV+G+TPAGQKTCLH+HG PY
Sbjct: 1 MFSVRIVTADYYMASPLQGLDTCQSPLTQAPVKKVPVVRVFGATPAGQKTCLHLHGIFPY 60
Query: 70 LYVSCSDIPLQLDQEGDAYTYMVASSLEKALKLK-GSADSSRQHVHGCSLVRAKKFYGYC 128
LYV Q+ ++Y +A S+++AL + G+ S+ QHV SLV FYGY
Sbjct: 61 LYVPYDG----YGQQPESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYH 116
Query: 129 SFEEFFVKIYLRYYPQDVSRAANLLLAGAVLNKSLQPHESHIPFILQFLVDYNLYGMGHL 188
E F+KIYL Y P V R LL +GA++NK QPHE+HIP++LQ +DYNLYGM +
Sbjct: 117 EKERHFMKIYL-YNPTMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLI 175
Query: 189 HLSKMRFRHPMPDSIHKKSDINSQHRKADPGAEACLESKIWMSSTISFDWMWSLPSESGG 248
+L+ ++FR +KS N+ H A ++ + +S + W +
Sbjct: 176 NLAAVKFR-----KARRKS--NTLH------ATGSCKNHLSGNSLADTLFRW---EQDEI 219
Query: 249 SSNDNTHSPKRQSICELEGDISVDEILNQQFKMFSSLSQTSSNVNMVQSLVSIWEEQRKR 308
S+ + QS CELE D +ILN+ + + L +IWE++++R
Sbjct: 220 PSSLILEGVEPQSTCELEVDAVAADILNR--------LDIEAQIGGNPGLQAIWEDEKQR 271
Query: 309 SGIHEATMLSDSGKPLPEDVMKLLSSGLDFEKKLIQLCSESDTTLS 354
T + + S F+K+L ++ ++D +++
Sbjct: 272 RRNRNETSQMSQPESQDHRFVPATESEKKFQKRLQEILKQNDFSVT 317
>DPOZ_MOUSE (Q61493) DNA polymerase zeta catalytic subunit (EC
2.7.7.7) (Seizure-related protein 4)
Length = 3122
Score = 691 bits (1782), Expect = 0.0
Identities = 389/898 (43%), Positives = 544/898 (60%), Gaps = 55/898 (6%)
Query: 1126 QDISQISGPGEKSSFTPLSQIGFQDPASAGHG-QQLALLSIEVLAESRGDLLPDPQFDAV 1184
++ SQI GP +++ I A A H Q L L+S+E+ A +R DL PDP+FD +
Sbjct: 2254 KETSQIDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLQPDPEFDPI 2313
Query: 1185 NIVALGFQKDCDAT-------VEVLVLLHSKFVPCQ--RSL------DGLSDCKVLNFTD 1229
+ D V+V+ K V Q RS G++ +V D
Sbjct: 2314 CALFYCISSDTPLPDTEKTELTGVIVIDKDKTVTHQDIRSQTPLLIRSGITGLEVTYAAD 2373
Query: 1230 EKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHLGFGLLNDLSRTPSNSWINSQ 1289
EK L +E T I+ DPDIL+G+EIQ S G+L +RA+ L L +SR P
Sbjct: 2374 EKALFQEITNIIKRYDPDILLGYEIQMHSWGYLLQRAAALSVDLCQMISRVP-------- 2425
Query: 1290 DIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHVGGRIVLNLWRLIRGEV 1349
D K + E D++G S +++ GRI LNLWR++R EV
Sbjct: 2426 DDKIENRFAAE-------------------RDDYGSDTMSEINIVGRITLNLWRIMRNEV 2466
Query: 1350 KLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYIVDRAKLNLEILNQL 1409
L Y+ E V+ VL ++ P VL+ WF R++ + + V R + NL++L QL
Sbjct: 2467 GLTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQL 2526
Query: 1410 DMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNYVAISPGNQQVASQPAMEC 1469
D++ +TSE+AR+FGI F VL+RGSQYRVESM LR+A NY+ ++P QQ + A +C
Sbjct: 2527 DLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSIQQRSQMRAPQC 2586
Query: 1470 LPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLGKVV---PSKTNTLGVSPFV 1526
+PL+MEPES FYS+ V+VLDFQSLYPS++IAYN CF TCLG V G +
Sbjct: 2587 VPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLR 2646
Query: 1527 PEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQAMKKLSPSEQVL 1586
+L ++ + ++PNGV FV +R+GVLPR+LEEIL TR+MVKQ+MK ++ L
Sbjct: 2647 VPPDLLYQIRHDVTVSPNGVAFVKPSVRKGVLPRMLEEILKTRLMVKQSMKSYK-QDRAL 2705
Query: 1587 QRIFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTLEKAISFVNLHEKW 1646
R+ NARQL LKLI+NVT+GYTAA FSGRMPC E+ DSIV R TLE+AI VN +KW
Sbjct: 2706 SRMLNARQLGLKLIANVTFGYTAANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKW 2765
Query: 1647 NAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAITAMNPSPVTLKMEKVYHPCFLITKK 1706
A+V+YGDTDSMFVLLKG T +++F+IG EIA A+TA NP PV LK EKVY PC L TKK
Sbjct: 2766 GARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPRPVKLKFEKVYLPCVLQTKK 2825
Query: 1707 RYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQSLRLFFEHQSLLEVKTYLQRQ 1766
RYVGY YE +Q EPVFDAKGIETVRRD+C AV+KI+E+SL+L FE + + +K Y+ RQ
Sbjct: 2826 RYVGYMYETLDQKEPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVHRQ 2885
Query: 1767 WKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVATKAMRVDRRAEPRYAERIPYV 1826
+++ G+ S++DFIFAKE R G++S R + PA + K + DRR+EPR ER+PYV
Sbjct: 2886 CMKLVEGKASIQDFIFAKEYR-GSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYV 2944
Query: 1827 VIHGEPGARLVDMVVDPLEVLAIDSPFRINDLYYINKQIIPALQRVFGLVGADLNQWFAE 1886
+I+G PG L+ ++ P EVL D R+N YYI KQI+P L R+F L+G D+ W+ E
Sbjct: 2945 IIYGTPGLPLIQLIRRPAEVLQ-DPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYQE 3003
Query: 1887 MPRPVREASVKHAFTPNFQRTRIDYYYLSKHCVLCGGLVQASARLCSQCSENEVAAATAV 1946
+PR +++A+ ++ I Y+ + HC +C L Q +CS+C A +
Sbjct: 3004 LPR-IQKATSSSRSELEGRKGTISQYFTTLHCPVCDDLTQHG--ICSKCRSQPQHVAIIL 3060
Query: 1947 IGKTAKLEQEMQHLVSICQHCGGGDRLLESGVKCTSISCLVFYERRKVQKELLAATHV 2004
+ +LE++ + L+ IC++C G + + C S++C V ++ +V +EL A ++
Sbjct: 3061 NQEIRELERKQEQLIKICRNCTGS---FDRHIPCVSLNCPVLFKLSRVNRELSKAPYL 3115
Score = 188 bits (478), Expect = 1e-46
Identities = 124/349 (35%), Positives = 191/349 (54%), Gaps = 36/349 (10%)
Query: 10 VFSVRIVSVDHYMASPIPSIDISHSTFHRGKVNEVPVIRVYGSTPAGQKTCLHIHGALPY 69
+FSVRIV+ D+YMASP+P +D S + V +VPV+RV+G+TPAGQKTCLH+HG PY
Sbjct: 1 MFSVRIVTADYYMASPLPGLDTCQSPLTQLPVKKVPVVRVFGATPAGQKTCLHLHGIFPY 60
Query: 70 LYVSCSDIPLQLDQEGDAYTYMVASSLEKALKLK-GSADSSRQHVHGCSLVRAKKFYGYC 128
LYV Q+ ++Y +A S+++AL + G+ S+ QHV SLV FYGY
Sbjct: 61 LYVPYDG----YGQQPESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYH 116
Query: 129 SFEEFFVKIYLRYYPQDVSRAANLLLAGAVLNKSLQPHESHIPFILQFLVDYNLYGMGHL 188
E F+KIYL Y P V R LL +GA++NK QPHE+HIP++LQ +DYNLYGM +
Sbjct: 117 EKERHFMKIYL-YNPAMVKRICELLQSGAIMNKCYQPHEAHIPYLLQLFIDYNLYGMNLI 175
Query: 189 HLSKMRFRHPMPDSIHKKSDINSQHRKADPGAEACLESKIWMSSTISFDWMWSLPSESGG 248
+L+ ++FR +K N+ H A + ++ +S + W E
Sbjct: 176 NLAAVKFR-----KARRKG--NASH------ATGLFKHQLSGNSPAGTLFRW---EEDEI 219
Query: 249 SSNDNTHSPKRQSICELEGDISVDEILNQQFKMFSSLSQTSSNVNMVQSLVSIWE-EQRK 307
S+ + S CELE D +ILN+ + + L +IWE E+++
Sbjct: 220 PSSLLLEGVEPLSTCELEVDAVAADILNR--------LDIEAQIGGNPGLQAIWEDEKQR 271
Query: 308 RSGIHEATMLSDSGKPLPED--VMKLLSSGLDFEKKLIQLCSESDTTLS 354
R +E++ +S +P +D + S F+K+L ++ ++D +++
Sbjct: 272 RRNRNESSQIS---QPESQDCRFVPATESEKQFQKRLQEVLKQNDFSVT 317
>DPOZ_YEAST (P14284) DNA polymerase zeta catalytic subunit (EC
2.7.7.7)
Length = 1504
Score = 617 bits (1591), Expect = e-175
Identities = 356/938 (37%), Positives = 534/938 (55%), Gaps = 93/938 (9%)
Query: 1095 LRPELHQDTEK---KLPCINEGQTE-RIKAHMDHSQDI----SQISGPGEKSSFTPLSQI 1146
L+P + +K K+P + +TE +I H HS+ + S +SG ++
Sbjct: 608 LKPPTYDAVQKWYNKVPSMGNKKTESQISMHTPHSKFLYKFASDVSGKQKRKK------- 660
Query: 1147 GFQDPASAGHGQQLALLSIEVLAESRGDLLPDPQFDAVNIVAL-----GFQKDCDATVEV 1201
S+ H L L++E+ A +R D +PDP D V+++ F D D E
Sbjct: 661 ------SSVH-DSLTHLTLEIHANTRSDKIPDPAIDEVSMIIWCLEEETFPLDLDIAYEG 713
Query: 1202 LVLLH---------SKFVPCQRSLDGLSDCKVLNFTDEKHLLKEFTKIVSSSDPDILMGW 1252
++++H +K C +++ V+ + E + + T +V DPDIL G+
Sbjct: 714 IMIVHKASEDSTFPTKIQHC------INEIPVMFYESEFEMFEALTDLVLLLDPDILSGF 767
Query: 1253 EIQGSSLGFLAERASHLG-FGLLNDLSRTPSNSWINSQDIKTSEKSILEPDIPDTTSLDC 1311
EI S G++ ER + F ++ +L+R IKT
Sbjct: 768 EIHNFSWGYIIERCQKIHQFDIVRELARVKCQ-------IKTK----------------- 803
Query: 1312 CARESSIIEDEWGRTHASGVHVGGRIVLNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSL 1371
+ D WG H+SG+ + GR ++N+WR +R +V L Y++E+ A +L +++P
Sbjct: 804 -------LSDTWGYAHSSGIMITGRHMINIWRALRSDVNLTQYTIESAAFNILHKRLPHF 856
Query: 1372 NHNVLTK-WFSRGPGQARYQCIKYIVDRAKLNLEILNQLDMVNRTSELARVFGIDFFSVL 1430
+ LT W ++ + Y + RA++N+++L + D + R E AR+ GIDF SV
Sbjct: 857 SFESLTNMWNAKKSTTELKTVLNYWLSRAQINIQLLRKQDYIARNIEQARLIGIDFHSVY 916
Query: 1431 SRGSQYRVESMFLRLAHTQNYVAISPGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDF 1490
RGSQ++VES +R+ +++++ +SPG + V Q A+EC+PLVMEPES FY P++VLDF
Sbjct: 917 YRGSQFKVESFLIRICKSESFILLSPGKKDVRKQKALECVPLVMEPESAFYKSPLIVLDF 976
Query: 1491 QSLYPSMIIAYNLCFCTCLGKV--VPSKTNTLGVSPFVPEQHILQDLKDQILLTPNGVMF 1548
QSLYPS++I YN C+ T +G+V + N LGVS F ++IL LK+ + + PNGV++
Sbjct: 977 QSLYPSIMIGYNYCYSTMIGRVREINLTENNLGVSKFSLPRNILALLKNDVTIAPNGVVY 1036
Query: 1549 VPSKIRRGVLPRLLEEILSTRIMVKQAMKKLSPSEQVLQRIFNARQLALKLISNVTYGYT 1608
+ +R+ L ++L +IL R+M+K+ M ++ L+R+ N +QLALKL++NVTYGYT
Sbjct: 1037 AKTSVRKSTLSKMLTDILDVRVMIKKTMNEIGDDNTTLKRLLNNKQLALKLLANVTYGYT 1096
Query: 1609 AAGFSGRMPCAELADSIVQCGRCTLEKAISFVNLHEKWNAKVIYGDTDSMFVLLKGRTAK 1668
+A FSGRMPC++LADSIVQ GR TLEKAI + E WNAKV+YGDTDS+FV L G+TA
Sbjct: 1097 SASFSGRMPCSDLADSIVQTGRETLEKAIDIIEKDETWNAKVVYGDTDSLFVYLPGKTAI 1156
Query: 1669 EAFQIGSEIASAITAMNPSPVTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGI 1728
EAF IG +A +T NP P+ LK EKVYHP LI+KKRYVG+SYE+P+Q P+FDAKGI
Sbjct: 1157 EAFSIGHAMAERVTQNNPKPIFLKFEKVYHPSILISKKRYVGFSYESPSQTLPIFDAKGI 1216
Query: 1729 ETVRRDTCEAVAKIMEQSLRLFFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRL 1788
ETVRRD A KI+E+ +RL F+ + L ++K YLQ ++ +I G+VS +DF FAKEV+L
Sbjct: 1217 ETVRRDGIPAQQKIIEKCIRLLFQTKDLSKIKKYLQNEFFKIQIGKVSAQDFCFAKEVKL 1276
Query: 1789 GTYSARISSLPPAAIVATKAMRVDRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLA 1848
G Y + + P A+V + + D RAEP+Y ERIPY+V+ G+ G L + V P E L
Sbjct: 1277 GAYKSE-KTAPAGAVVVKRRINEDHRAEPQYKERIPYLVVKGKQGQLLRERCVSPEEFLE 1335
Query: 1849 IDSPFRINDLYYINKQIIPALQRVFGLVGADLNQWFAEMPRPVREASVKHAFTPNFQRTR 1908
++ ++ YYINK +IP L R+F L+G ++ W E+ + K A T +
Sbjct: 1336 GEN-LELDSEYYINKILIPPLDRLFNLIGINVGNWAQEIVKS------KRASTTTTKVEN 1388
Query: 1909 IDYYYLSKHCVLCGGLVQ--ASARLCSQCSENEVAAATAVIGKTAKLEQEMQHLVSICQH 1966
I S C CG + S +LC C E + + K K ++E Q L ++C+
Sbjct: 1389 ITRVGTSATCCNCGEELTKICSLQLCDDCLEKRSTTTLSFLIKKLKRQKEYQTLKTVCRT 1448
Query: 1967 CG---GGDRLLES---GVKCTSISCLVFYERRKVQKEL 1998
C D +E+ KC S C VFY R K ++ L
Sbjct: 1449 CSYRYTSDAGIENDHIASKCNSYDCPVFYSRVKAERYL 1486
Score = 100 bits (249), Expect = 4e-20
Identities = 64/213 (30%), Positives = 105/213 (49%), Gaps = 15/213 (7%)
Query: 4 SESNSDVFSVRIVSVDHYMASPIPSIDISHS-TFHRGKVNEVPVIRVYGSTPAGQKTCLH 62
S S SD F +++ + D+YM+ P +D SH + + ++VP IRV+G+ P G + H
Sbjct: 16 SSSKSDYFRIQLNNQDYYMSKPT-FLDPSHGESLPLNQFSQVPNIRVFGALPTGHQVLCH 74
Query: 63 IHGALPYLYVSCSDIPLQLDQEGDAYTYMVASSLEKALK------------LKGSADSSR 110
+HG LPY+++ V +LE ++ L G +
Sbjct: 75 VHGILPYMFIKYDGQITDTSTLRHQRCAQVHKTLEVKIRASFKRKKDDKHDLAGDKLGNL 134
Query: 111 QHVHGCSLVRAKKFYGYCSFEEFFVKIYLRYYPQDVSRAANLLLAGAVLNKSLQPHESHI 170
V S+V+ FYGY F KI L P +SR + L+ G + K + +ESHI
Sbjct: 135 NFVADVSVVKGIPFYGYHVGWNLFYKISL-LNPSCLSRISELIRDGKIFGKKFEIYESHI 193
Query: 171 PFILQFLVDYNLYGMGHLHLSKMRFRHPMPDSI 203
P++LQ+ D+NL+G +++ + FR P+ +SI
Sbjct: 194 PYLLQWTADFNLFGCSWINVDRCYFRSPVLNSI 226
>DPOD_ORYSA (Q9LRE6) DNA polymerase delta catalytic subunit (EC
2.7.7.7)
Length = 1105
Score = 323 bits (828), Expect = 3e-87
Identities = 253/872 (29%), Positives = 405/872 (46%), Gaps = 100/872 (11%)
Query: 1152 ASAGHGQQLA---LLSIEVLAESRGDLLPDPQFDAVNIVALGFQKDCDATVEVLVLLHSK 1208
A+ G ++A +LS ++ R P+P D V +A LV L +
Sbjct: 303 AAEGEHSKMAPFRILSFDIECAGRKGHFPEPTHDPVIQIAN------------LVTLQGE 350
Query: 1209 FVPCQRSLDGLSDCK------VLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFL 1262
P R++ L C V++F E+ +L + + DPDI++G+ I L +L
Sbjct: 351 GQPFVRNVMTLKSCSPIVGVDVMSFDTERDVLLAWRDFIREVDPDIIIGYNICKFDLPYL 410
Query: 1263 AERASHLGFGLLNDLSRTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDE 1322
ERA L L R I+ S + R+++ +
Sbjct: 411 IERAEVLKIVEFPILGR-----------IRNSRVRV---------------RDTTFSSRQ 444
Query: 1323 WGRTHASGVHVGGRIVLNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSR 1382
+G + V V GR+ +L + ++ + KL+ YS+ +V+ L + ++H++++
Sbjct: 445 YGMRESKDVAVEGRVQFDLLQAMQRDYKLSSYSLNSVSAHFLGEQKEDVHHSIISD-LQN 503
Query: 1383 GPGQARYQCIKYIVDRAKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMF 1442
G + R + Y + A L +L++L + E+ARV G+ +LSRG +V S
Sbjct: 504 GNSETRRRLAVYCLKDAYLPQRLLDKLMYIYNYVEMARVTGVPISFLLSRGQSIKVLSQL 563
Query: 1443 LRLAHTQNYVAISPGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYN 1502
LR A +N V I Q + Q E V+E +GFY P+ LDF SLYPS+++AYN
Sbjct: 564 LRKAKQKNLV-IPNIKGQASGQDTFEG-ATVLEARAGFYEKPIATLDFASLYPSIMMAYN 621
Query: 1503 LCFCTCLGKVVPSKTNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLL 1562
LC+CT V P L + P + + TP+G FV +++G+LP +L
Sbjct: 622 LCYCTL---VPPEDARKLNLPP------------ESVNKTPSGETFVKPDVQKGILPEIL 666
Query: 1563 EEILSTRIMVKQAMKKLSPSEQVLQR-IFNARQLALKLISNVTYGYTAAGFSGRMPCAEL 1621
EE+L+ R K+A L ++ +R + + RQLALK+ +N YG+T A G++PC E+
Sbjct: 667 EELLAAR---KRAKADLKEAKDPFERAVLDGRQLALKISANSVYGFTGATV-GQLPCLEI 722
Query: 1622 ADSIVQCGRCTLEKAISFVNLHEKW--------NAKVIYGDTDSMFVLLKGRTAKEAFQI 1673
+ S+ GR +E V +K+ NA+VIYGDTDS+ V T ++A ++
Sbjct: 723 SSSVTSYGRQMIEHTKKLV--EDKFTTLGGYEHNAEVIYGDTDSVMVQFGVSTVEDAMKL 780
Query: 1674 GSEIASAITAMNPSPVTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRR 1733
G E A I+ P+ L+ EK+Y P LI+KKRY G + NP + + + D KGIETVRR
Sbjct: 781 GREAADYISGTFIKPIKLEFEKIYFPYLLISKKRYAGLYWTNPEKFDKM-DTKGIETVRR 839
Query: 1734 DTCEAVAKIMEQSLRLFFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSA 1793
D C V ++ + L + + Y++ +L RV L + K + T +
Sbjct: 840 DNCLLVKNLVTECLHKILVDRDVPGAVQYVKNTISDLLMNRVDLSLLVITKGL---TKTG 896
Query: 1794 RISSLPPAAIVATKAMRV-DRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSP 1852
++ A + + MR D P +R+PYV+I GA+ + DP+ VL D+
Sbjct: 897 EDYAVKAAHVELAERMRKRDAATAPTVGDRVPYVIIKAAKGAKAYERSEDPIYVL--DNN 954
Query: 1853 FRINDLYYINKQIIPALQRVFG--LVGADLNQWFAEMPRPVREASVKHAFTPNFQRTRID 1910
I+ YY+ QI L R+F L A R V ++ ++ F + ++
Sbjct: 955 IPIDPQYYLENQISKPLLRIFEPILKNASRELLHGSHTRAVSISTPSNSGIMKFAKKQLT 1014
Query: 1911 YYYLSKHCVLCGGLVQASAR-LCSQCSENEVAAATAVIGKTAKLEQEMQHLVSICQHCGG 1969
C+ C ++ S + LC C E +G ++LE L + CQ C G
Sbjct: 1015 -------CLGCKAVISGSNQTLCFHCKGREAELYCKTVGNVSELEMLFGRLWTQCQECQG 1067
Query: 1970 GDRLLESGVKCTSISCLVFYERRKVQKELLAA 2001
L V CTS C +FY RRK QK++ A
Sbjct: 1068 S---LHQDVLCTSRDCPIFYRRRKAQKDMAEA 1096
Score = 51.2 bits (121), Expect = 3e-05
Identities = 40/158 (25%), Positives = 71/158 (44%), Gaps = 12/158 (7%)
Query: 32 SHSTFHRGKVNEVPVIRVYGSTPAGQKTCLHIHGALPYLYVSCSDIPLQLDQEGDAYTYM 91
SH ++R++G T G C +HG PY Y+SC P+ + + + +
Sbjct: 117 SHKVLLPNSSGPAAILRIFGVTREGHSVCCQVHGFEPYFYISC---PMGMGPDDISRFH- 172
Query: 92 VASSLEKALKLKGSADSSRQHVHGCSLVRAKKFYGYCSFE-EFFVKIYLRYYPQDVSRAA 150
+LE +K + + V LV+ + Y + + F+KI + P V+
Sbjct: 173 --QTLEGRMKDSNRNSNVPRFVKRIELVQKQTIMHYQPQQSQPFLKIVVA-LPTMVASCR 229
Query: 151 NLLLAGAVL----NKSLQPHESHIPFILQFLVDYNLYG 184
+L G + +KS +ES+I F L+F++D N+ G
Sbjct: 230 GILERGITIEGLGSKSFLTYESNILFALRFMIDCNIVG 267
>DPOD_BOVIN (P28339) DNA polymerase delta catalytic subunit (EC
2.7.7.7)
Length = 1106
Score = 317 bits (812), Expect = 2e-85
Identities = 247/852 (28%), Positives = 386/852 (44%), Gaps = 85/852 (9%)
Query: 1160 LALLSIEVLAESRGDLLPDPQFDAV-NIVALGFQKDCDATVEVLVLLHSKFVPCQRSLDG 1218
L +LS ++ R + P+P+ D V I +LG + E + L PC L
Sbjct: 309 LRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRW---GEPEPFLRLALTLRPCAPILGA 365
Query: 1219 LSDCKVLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHL---GFGLLN 1275
KV ++ E+ LL+ ++ + DPD++ G+ IQ L +L RA L GF LL
Sbjct: 366 ----KVQSYEREEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVPGFPLLG 421
Query: 1276 DLSRTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHVGG 1335
+ SN RESS + GR + V + G
Sbjct: 422 RVIGLRSN-----------------------------IRESSFQSRQTGRRDSKVVSMVG 452
Query: 1336 RIVLNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYI 1395
R+ +++ +++ E KL Y++ AV+ L + + H+++T G Q R + Y
Sbjct: 453 RVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITD-LQNGNDQTRRRLAVYC 511
Query: 1396 VDRAKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNY---V 1452
+ A L L +L +L ++ E+ARV G+ +LSRG Q +V S LR A Q V
Sbjct: 512 LKDAFLPLRLLERLMVLVNAMEMARVTGVPLGYLLSRGQQVKVVSQLLRQAMRQGLLMPV 571
Query: 1453 AISPGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLGKV 1512
+ G + V+EP G+Y P+ LDF SLYPS+++A+NLC+ T L
Sbjct: 572 VKTEGGEDYTGAT-------VIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLR-- 622
Query: 1513 VPSKTNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMV 1572
P LG++ +DQ + TP G FV + +R+G+LP++LE +LS R
Sbjct: 623 -PGAAQKLGLT------------EDQFIKTPTGDEFVKASVRKGLLPQILENLLSARKRA 669
Query: 1573 KQAMKKLSPSEQVLQRIFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCT 1632
K + K ++ + +++ + RQLALK+ +N YG+T A GR+PC E++ S+ GR
Sbjct: 670 KAELAK--ETDPLRRQVLDGRQLALKVSANSVYGFTGAQV-GRLPCLEISQSVTGFGRQM 726
Query: 1633 LEKAISFVNLHE------KWNAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAITAMNP 1686
+EK V +AKV+YGDTDS+ + EA +G E A ++ P
Sbjct: 727 IEKTKQLVETKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFP 786
Query: 1687 SPVTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQS 1746
SP+ L+ EKVY P LI+KKRY G + + D KG+E VRRD C VA ++ S
Sbjct: 787 SPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTAS 846
Query: 1747 LRLFFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVAT 1806
LR + + Q +L R+ + + KE L +A + +A
Sbjct: 847 LRRLLIDRDPSGAVAHAQDVISDLLCNRIDISQLVITKE--LTRAAADYAGKQAHVELAE 904
Query: 1807 KAMRVDRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSPFRINDLYYINKQII 1866
+ + D + P +R+PYV+I G DPL VL P I+ YY+ +Q+
Sbjct: 905 RMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLP--IDTQYYLEQQLA 962
Query: 1867 PALQRVFGLVGADLNQWFAEMPRPVREASVKHAFTPNFQRTRIDYYYLSKHCVLCGGLVQ 1926
L R+F + L + AE + + + + C+ C ++
Sbjct: 963 KPLLRIFEPI---LGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVLS 1019
Query: 1927 ASARLCSQCSENEVAAATAVIGKTAKLEQEMQHLVSICQHCGGGDRLLESGVKCTSISCL 1986
+C C E + + LE+ L + CQ C G L V CTS C
Sbjct: 1020 HQGAVCKFCQPRESELYQKEVSHLSALEERFSRLWTQCQRCQGS---LHEDVICTSRDCP 1076
Query: 1987 VFYERRKVQKEL 1998
+FY R+KV+K+L
Sbjct: 1077 IFYMRKKVRKDL 1088
Score = 51.2 bits (121), Expect = 3e-05
Identities = 47/184 (25%), Positives = 77/184 (41%), Gaps = 23/184 (12%)
Query: 16 VSVDHYMAS--PIPSIDISHSTFHRGKVNEVPVIRVYGSTPAGQKTCLHIHGALPYLYVS 73
+ +DHY+A P+P + VP++R +G T G C HIHG PY Y
Sbjct: 98 LEIDHYVAPARPLPGAPPPSQ-------DSVPILRAFGVTNEGVSVCCHIHGFAPYFYTP 150
Query: 74 CSDIPLQLDQEGDAYTYMVASSLEKALK--LKGSADSSRQHVHGCSLVRAKKFYGYCSF- 130
G + + L A+ +G + + V L + +GY
Sbjct: 151 AP------PGFGPEHLSELQRELSAAISRDQRGGKELTGPAVLAVELCSRESMFGYHGHG 204
Query: 131 EEFFVKIYLRYYPQDVSRAANLLLAGAVL----NKSLQPHESHIPFILQFLVDYNLYGMG 186
F++I L P+ ++ A LL G L S P+E+++ F ++F+VD ++ G
Sbjct: 205 PSPFLRITLA-LPRLMAPARRLLEQGIRLAGLGTPSFAPYEANVDFEIRFMVDTDIVGCN 263
Query: 187 HLHL 190
L L
Sbjct: 264 WLEL 267
>DPOD_MOUSE (P52431) DNA polymerase delta catalytic subunit (EC
2.7.7.7)
Length = 1105
Score = 317 bits (811), Expect = 3e-85
Identities = 246/852 (28%), Positives = 389/852 (44%), Gaps = 85/852 (9%)
Query: 1160 LALLSIEVLAESRGDLLPDPQFDAV-NIVALGFQKDCDATVEVLVLLHSKFVPCQRSLDG 1218
L +LS ++ R + P+P+ D V I +LG + E + L PC L
Sbjct: 308 LRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRW---GEPEPFLRLALTLRPCAPILGA 364
Query: 1219 LSDCKVLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHLGFGLLNDLS 1278
KV ++ E+ LL+ + + + DPD++ G+ IQ L +L RA L L
Sbjct: 365 ----KVQSYEREEDLLQAWADFILAMDPDVITGYNIQNFDLPYLISRAQALKVDRFPFLG 420
Query: 1279 RTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHVGGRIV 1338
R T L R+SS + GR + + + GR+
Sbjct: 421 RV--------------------------TGLRSNIRDSSFQSRQVGRRDSKVISMVGRVQ 454
Query: 1339 LNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYIVDR 1398
+++ +++ E KL Y++ AV+ L + + H+++T G Q R + Y +
Sbjct: 455 MDMLQVLLREHKLRSYTLNAVSFHFLGEQKEDVQHSIITD-LQNGNEQTRRRLAVYCLKD 513
Query: 1399 AKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNY---VAIS 1455
A L L +L +L ++ E+ARV G+ +L+RG Q +V S LR A Q V +
Sbjct: 514 AFLPLRLLERLMVLVNNVEMARVTGVPLGYLLTRGQQVKVVSQLLRQAMRQGLLMPVVKT 573
Query: 1456 PGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLGKVVPS 1515
G + V+EP G+Y P+ LDF SLYPS+++A+NLC+ T L P
Sbjct: 574 EGGEDYTGAT-------VIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLR---PG 623
Query: 1516 KTNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQA 1575
LG+ P D+ + TP G FV S +R+G+LP++LE +LS R K+A
Sbjct: 624 AAQKLGLKP------------DEFIKTPTGDEFVKSSVRKGLLPQILENLLSAR---KRA 668
Query: 1576 MKKLSPSEQVLQR-IFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTLE 1634
+L+ L+R + + RQLALK+ +N YG+T A G++PC E++ S+ GR +E
Sbjct: 669 KAELAQETDPLRRQVLDGRQLALKVSANSVYGFTGAQV-GKLPCLEISQSVTGFGRQMIE 727
Query: 1635 KAISFVNLHEKW--------NAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAITAMNP 1686
K V K+ NAKV+YGDTDS+ + EA +G E A+ +++ P
Sbjct: 728 KTKQLVE--SKYTVENGYDANAKVVYGDTDSVMCRFGVSSVAEAMSLGREAANWVSSHFP 785
Query: 1687 SPVTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQS 1746
SP+ L+ EKVY P LI+KKRY G + + + D KG+E VRRD C VA ++ S
Sbjct: 786 SPIRLEFEKVYFPYLLISKKRYAGLLFSSRSDAHDKMDCKGLEAVRRDNCPLVANLVTSS 845
Query: 1747 LRLFFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVAT 1806
LR + + + +L R+ + + KE L +A + +A
Sbjct: 846 LRRILVDRDPDGAVAHAKDVISDLLCNRIDISQLVITKE--LTRAAADYAGKQAHVELAE 903
Query: 1807 KAMRVDRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSPFRINDLYYINKQII 1866
+ + D + P +R+PYV+I G DPL VL P I+ YY+ +Q+
Sbjct: 904 RMRKRDPGSAPSLGDRVPYVIIGAAKGVAAYMKSEDPLFVLEHSLP--IDTQYYLEQQLA 961
Query: 1867 PALQRVFGLVGADLNQWFAEMPRPVREASVKHAFTPNFQRTRIDYYYLSKHCVLCGGLVQ 1926
L R+F + L + AE + + + + + C+ C ++
Sbjct: 962 KPLLRIFEPI---LGEGRAESVLLRGDHTRCKTVLTSKVGGLLAFTKRRNCCIGCRSVID 1018
Query: 1927 ASARLCSQCSENEVAAATAVIGKTAKLEQEMQHLVSICQHCGGGDRLLESGVKCTSISCL 1986
+C C E + + LE+ L + CQ C G L V CTS C
Sbjct: 1019 HQGAVCKFCQPRESELSQKEVSHLNALEERFSRLWTQCQRCQGS---LHEDVICTSRDCP 1075
Query: 1987 VFYERRKVQKEL 1998
+FY R+KV+K+L
Sbjct: 1076 IFYMRKKVRKDL 1087
Score = 52.4 bits (124), Expect = 1e-05
Identities = 50/187 (26%), Positives = 83/187 (43%), Gaps = 29/187 (15%)
Query: 16 VSVDHYMAS--PIPSIDISHSTFHRGKVNEVPVIRVYGSTPAGQKTCLHIHGALPYLYVS 73
+ +DHY+ S P+P + N VP++R +G T G C HI G PY Y
Sbjct: 97 LEIDHYVGSAPPLPERPLPSR-------NSVPILRAFGVTDEGFSVCCHIQGFAPYFYTP 149
Query: 74 C-----SDIPLQLDQEGDAYTYMVASSLEKALKLKGSADSSRQHVHGCSLVRAKKFYGYC 128
++ +L QE +A A S ++ +G + S V L + +GY
Sbjct: 150 APPGFGAEHLSELQQELNA-----AISRDQ----RGGKELSGPAVLAIELCSRESMFGYH 200
Query: 129 SF-EEFFVKIYLRYYPQDVSRAANLLLAGAVL----NKSLQPHESHIPFILQFLVDYNLY 183
F++I L P+ ++ A LL G + S P+E+++ F ++F+VD ++
Sbjct: 201 GHGPSPFLRITLA-LPRLMAPARRLLEQGVRVPGLGTPSFAPYEANVDFEIRFMVDADIV 259
Query: 184 GMGHLHL 190
G L L
Sbjct: 260 GCNWLEL 266
>DPOD_RAT (O54747) DNA polymerase delta catalytic subunit (EC 2.7.7.7)
Length = 1103
Score = 316 bits (809), Expect = 5e-85
Identities = 245/850 (28%), Positives = 385/850 (44%), Gaps = 81/850 (9%)
Query: 1160 LALLSIEVLAESRGDLLPDPQFDAV-NIVALGFQKDCDATVEVLVLLHSKFVPCQRSLDG 1218
L +LS ++ R + P+P+ D V I +LG + E + L PC L
Sbjct: 306 LRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRW---GEPEPFLRLALTLRPCAPILGA 362
Query: 1219 LSDCKVLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHLGFGLLNDLS 1278
KV ++ E+ LL+ + + + DPD++ G+ IQ L +L RA L L
Sbjct: 363 ----KVQSYEREEDLLQAWATFILAMDPDVITGYNIQNFDLPYLISRAQTLKVDRFPFLG 418
Query: 1279 RTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHVGGRIV 1338
R T L R+SS + GR + V + GR+
Sbjct: 419 RV--------------------------TGLRSNIRDSSFQSRQVGRRDSKVVSMVGRVQ 452
Query: 1339 LNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYIVDR 1398
+++ +++ E KL Y++ AV+ L + + H+++T G Q R + Y +
Sbjct: 453 MDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITD-LQNGNEQTRRRLAVYCLKD 511
Query: 1399 AKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNY---VAIS 1455
A L L +L +L ++ E+ARV G+ +LSRG Q +V S LR A + V +
Sbjct: 512 AFLPLRLLERLMVLVNNVEMARVTGVPLGYLLSRGQQVKVVSQLLRQAMREGLLMPVVKT 571
Query: 1456 PGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLGKVVPS 1515
G + V+EP G+Y P+ LDF SLYPS+++A+NLC+ T L P
Sbjct: 572 EGGEDYTGAT-------VIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLR---PG 621
Query: 1516 KTNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQA 1575
LG+ P D+ + TP G FV + +R+G+LP++LE +LS R K+A
Sbjct: 622 AAQKLGLKP------------DEFIKTPTGDEFVKASVRKGLLPQILENLLSAR---KRA 666
Query: 1576 MKKLSPSEQVLQR-IFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTLE 1634
+L+ L+R + + RQLALK+ N YG+T A G++PC E++ S+ GR +E
Sbjct: 667 KAELAQETDPLRRQVLDGRQLALKVSPNSVYGFTGAQV-GKLPCLEISQSVTGFGRQMIE 725
Query: 1635 KAISFVNLHEKW------NAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAITAMNPSP 1688
K V NAKV+YGDTDS+ + EA +G E A+ +++ PSP
Sbjct: 726 KTKQLVETKYTLENGYDANAKVVYGDTDSVMCRFGVSSVAEAMSLGREAANWVSSHFPSP 785
Query: 1689 VTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQSLR 1748
+ L+ EKVY P LI+KKRY G + + + D KG+E VRRD C VA ++ SLR
Sbjct: 786 IRLEFEKVYFPYLLISKKRYAGLLFSSRSDAHDRMDCKGLEAVRRDNCPLVANLVTSSLR 845
Query: 1749 LFFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVATKA 1808
+ + + +L R+ + + KE L +A + +A +
Sbjct: 846 RILVDRDPDGAVAHAKDVISDLLCNRIDISQLVITKE--LTRAAADYAGKQAHVELAERM 903
Query: 1809 MRVDRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSPFRINDLYYINKQIIPA 1868
+ D + P +R+PYV+I G DPL VL P I+ YY+ +Q+
Sbjct: 904 RKRDPGSAPNLGDRVPYVIIGAAKGVAAYMKSEDPLFVLEHSLP--IDTQYYLEQQLAKP 961
Query: 1869 LQRVFGLVGADLNQWFAEMPRPVREASVKHAFTPNFQRTRIDYYYLSKHCVLCGGLVQAS 1928
L R+F + L + AE + + + + + C+ C ++
Sbjct: 962 LLRIFEPI---LGEGRAESVLLRGDHTRCKTVLTSKVGGLLAFTKRRNSCIGCRSVIDHQ 1018
Query: 1929 ARLCSQCSENEVAAATAVIGKTAKLEQEMQHLVSICQHCGGGDRLLESGVKCTSISCLVF 1988
+C C E + LE+ L + CQ C G L V CTS C +F
Sbjct: 1019 GAVCKFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGS---LHEDVICTSRDCPIF 1075
Query: 1989 YERRKVQKEL 1998
Y R+KV+K+L
Sbjct: 1076 YMRKKVRKDL 1085
Score = 51.2 bits (121), Expect = 3e-05
Identities = 46/182 (25%), Positives = 78/182 (42%), Gaps = 19/182 (10%)
Query: 16 VSVDHYMASPIPSIDISHSTFHRGKVNEVPVIRVYGSTPAGQKTCLHIHGALPYLYVSCS 75
+ +DHY+ + P + ++ N VP++R +G T G C HIHG PY Y
Sbjct: 95 LEIDHYVGTSPPLPEGPPASR-----NSVPILRAFGVTDEGFSVCCHIHGFAPYFYTPAP 149
Query: 76 DIPLQLDQEGDAYTYMVASSLEKALK--LKGSADSSRQHVHGCSLVRAKKFYGYCSF-EE 132
G + + L A+ +G + S V L + +GY
Sbjct: 150 ------PGFGAEHLSELQRELNAAISRDQRGGKELSGPAVLAIELCSRESMFGYHGHGPS 203
Query: 133 FFVKIYLRYYPQDVSRAANLLLAG----AVLNKSLQPHESHIPFILQFLVDYNLYGMGHL 188
F++I L P+ ++ A LL G + S P+E+++ F ++F+VD ++ G L
Sbjct: 204 PFLRITLA-LPRLMAPARRLLEQGIRVPGLGTPSFAPYEANVDFEIRFMVDADIVGCNWL 262
Query: 189 HL 190
L
Sbjct: 263 EL 264
>DPOD_MESAU (P97283) DNA polymerase delta catalytic subunit (EC
2.7.7.7)
Length = 1103
Score = 316 bits (809), Expect = 5e-85
Identities = 248/850 (29%), Positives = 387/850 (45%), Gaps = 81/850 (9%)
Query: 1160 LALLSIEVLAESRGDLLPDPQFDAV-NIVALGFQKDCDATVEVLVLLHSKFVPCQRSLDG 1218
L +LS ++ R + P+P+ D V I +LG + E + L PC L
Sbjct: 306 LRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRW---GEPEPFLRLALTLRPCAPILGA 362
Query: 1219 LSDCKVLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHLGFGLLNDLS 1278
KV ++ E+ LL+ + + + DPD++ G+ IQ L +L RA L L
Sbjct: 363 ----KVQSYEREEDLLQAWPNFILAMDPDVITGYNIQNFDLPYLISRAQTLKVDRFPFLG 418
Query: 1279 RTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHVGGRIV 1338
R T L R+SS + GR + V + GR+
Sbjct: 419 RV--------------------------TGLRSNIRDSSFQSRQVGRRDSKVVSMVGRVQ 452
Query: 1339 LNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYIVDR 1398
+++ +++ E KL Y++ AV+ L + + H+++T G Q R + Y +
Sbjct: 453 MDMLQVLLREHKLRSYTLNAVSFHFLGEQKEDVQHSIITD-LQNGNEQTRRRLAVYCLRD 511
Query: 1399 AKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNY---VAIS 1455
A L L +L +L ++ E+ARV G+ +LSRG Q +V S LR A Q V +
Sbjct: 512 AFLPLRLLERLMVLVNNVEMARVTGVPLGYLLSRGQQVKVVSQLLRQAMRQGLLMPVVKT 571
Query: 1456 PGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLGKVVPS 1515
G + V+EP G+Y P+ LDF SLYPS+++A+NLC+ T L P
Sbjct: 572 EGGEDYTGAT-------VIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLR---PG 621
Query: 1516 KTNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQA 1575
LG+ P D+ + TP G FV S +R+G+LP++LE +LS R K+A
Sbjct: 622 AAQKLGLKP------------DEFIKTPTGDEFVKSSVRKGLLPQILENLLSAR---KRA 666
Query: 1576 MKKLSPSEQVLQR-IFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTLE 1634
+L+ L+R + + RQLALK+ +N YG+T A G++PC E++ S+ GR +E
Sbjct: 667 KAELAQETDPLRRQVLDGRQLALKVSANSVYGFTGAEV-GKLPCLEISQSVTGFGRQMIE 725
Query: 1635 KAISFVN----LHEKWNA--KVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAITAMNPSP 1688
K V L +NA KV+YGDTDS+ + EA +G E A+ +++ PSP
Sbjct: 726 KTKQLVESKYTLENGYNANAKVVYGDTDSVMCRFGVSSVAEAMSLGREAANWVSSHFPSP 785
Query: 1689 VTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQSLR 1748
+ L+ EKVY P LI+KKRY G + + D KG+E VRRD C VA ++ SLR
Sbjct: 786 IRLEFEKVYFPYLLISKKRYAGLLFSSQPDTHDRMDCKGLEAVRRDNCPLVANLVTSSLR 845
Query: 1749 LFFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVATKA 1808
+ + + +L R+ + + KE L +A + +A +
Sbjct: 846 RILVDRDPDGAVAHAKDVISDLLCNRIDISQLVITKE--LTRAAADYAGKQAHVELAERM 903
Query: 1809 MRVDRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSPFRINDLYYINKQIIPA 1868
+ D + P +R+PYV+I G DPL VL P I+ YY+ +Q+
Sbjct: 904 RKRDPGSAPSLGDRVPYVIIGAAKGVAAYMKSEDPLFVLEHSLP--IDTQYYLGQQLAKP 961
Query: 1869 LQRVFGLVGADLNQWFAEMPRPVREASVKHAFTPNFQRTRIDYYYLSKHCVLCGGLVQAS 1928
L R+F + L + AE + + + + + C+ C ++
Sbjct: 962 LLRIFEPI---LGEGRAESVLLRGDHTRCKTVLTSKVGGLLAFTKRRNCCIGCRSVINHQ 1018
Query: 1929 ARLCSQCSENEVAAATAVIGKTAKLEQEMQHLVSICQHCGGGDRLLESGVKCTSISCLVF 1988
+C C E + LE+ L + CQ C G L V CTS C +F
Sbjct: 1019 GAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGS---LHEDVICTSRDCPIF 1075
Query: 1989 YERRKVQKEL 1998
Y R+KV+K+L
Sbjct: 1076 YMRKKVRKDL 1085
Score = 56.2 bits (134), Expect = 9e-07
Identities = 49/193 (25%), Positives = 83/193 (42%), Gaps = 19/193 (9%)
Query: 5 ESNSDVFSVRIVSVDHYMASPIPSIDISHSTFHRGKVNEVPVIRVYGSTPAGQKTCLHIH 64
+ N++ + + +DHY+ S +P ++ N VP++R +G T G C HIH
Sbjct: 84 DPNTEPLIFQQLEIDHYVGSAVPLPGGPPTS-----CNSVPILRAFGVTDEGFSVCCHIH 138
Query: 65 GALPYLYVSCSDIPLQLDQEGDAYTYMVASSLEKALK--LKGSADSSRQHVHGCSLVRAK 122
G PY Y G + + L A+ +G + S V L +
Sbjct: 139 GFAPYFYTPAP------PGFGAEHLSDLQRELSTAISRDQRGGKELSGPAVLAIELCSRE 192
Query: 123 KFYGYCSF-EEFFVKIYLRYYPQDVSRAANLLLAG----AVLNKSLQPHESHIPFILQFL 177
+GY F++I L P+ V+ A LL G + S P+E+++ F ++F+
Sbjct: 193 SMFGYHGHGPSPFLRITLA-LPRLVAPARRLLEQGIRVPGLGTPSFAPYEANVDFEIRFM 251
Query: 178 VDYNLYGMGHLHL 190
VD ++ G L L
Sbjct: 252 VDADIVGCNWLEL 264
>DPOD_HUMAN (P28340) DNA polymerase delta catalytic subunit (EC
2.7.7.7) (DNA polymerase delta subunit p125)
Length = 1107
Score = 310 bits (793), Expect = 3e-83
Identities = 244/850 (28%), Positives = 382/850 (44%), Gaps = 81/850 (9%)
Query: 1160 LALLSIEVLAESRGDLLPDPQFDAV-NIVALGFQKDCDATVEVLVLLHSKFVPCQRSLDG 1218
L +LS ++ R + P+P+ D V I +LG + E + L PC L
Sbjct: 310 LRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRW---GEPEPFLRLALTLRPCAPILGA 366
Query: 1219 LSDCKVLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHLGFGLLNDLS 1278
KV ++ E+ LL+ ++ + DPD++ G+ IQ L +L RA L L
Sbjct: 367 ----KVQSYEKEEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVQTFPFLG 422
Query: 1279 RTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHVGGRIV 1338
R L R+SS + GR V + GR+
Sbjct: 423 RV--------------------------AGLCSNIRDSSFQSKQTGRRDTKVVSMVGRVQ 456
Query: 1339 LNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYIVDR 1398
+++ +++ E KL Y++ AV+ L + + H+++T G Q R + Y +
Sbjct: 457 MDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITD-LQNGNDQTRRRLAVYCLKD 515
Query: 1399 AKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNY---VAIS 1455
A L L +L +L ++ E+ARV G+ +LSRG Q +V S LR A + V S
Sbjct: 516 AYLPLRLLERLMVLVNAVEMARVTGVPLSYLLSRGQQVKVVSQLLRQAMHEGLLMPVVKS 575
Query: 1456 PGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLGKVVPS 1515
G + V+EP G+Y P+ LDF SLYPS+++A+NLC+ T L P
Sbjct: 576 EGGEDYTGAT-------VIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLR---PG 625
Query: 1516 KTNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQA 1575
LG++ +DQ + TP G FV + +R+G+LP++LE +LS R K
Sbjct: 626 TAQKLGLT------------EDQFIRTPTGDEFVKTSVRKGLLPQILENLLSARKRAKAE 673
Query: 1576 MKKLSPSEQVLQRIFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTLEK 1635
+ K ++ + +++ + RQLALK+ +N YG+T A G++PC E++ S+ GR +EK
Sbjct: 674 LAK--ETDPLRRQVLDGRQLALKVSANSVYGFTGAQV-GKLPCLEISQSVTGFGRQMIEK 730
Query: 1636 AISFVNLHE------KWNAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAITAMNPSPV 1689
V +AKV+YGDTDS+ + EA +G E A ++ PSP+
Sbjct: 731 TKQLVESKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPI 790
Query: 1690 TLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQSLRL 1749
L+ EKVY P LI+KKRY G + + D KG+E VRRD C VA ++ SLR
Sbjct: 791 RLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRR 850
Query: 1750 FFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVATKAM 1809
+ + Q +L R+ + + KE+ T +A + A + + M
Sbjct: 851 LLIDRDPEGAVAHAQDVISDLLCNRIDISQLVITKEL---TRAASDYAGKQAHVELAERM 907
Query: 1810 RV-DRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSPFRINDLYYINKQIIPA 1868
R D + P +R+PYV+I G DPL VL P I+ YY+ +Q+
Sbjct: 908 RKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLP--IDTQYYLEQQLAKP 965
Query: 1869 LQRVFGLVGADLNQWFAEMPRPVREASVKHAFTPNFQRTRIDYYYLSKHCVLCGGLVQAS 1928
L R+F + L + AE + + + + C+ C ++
Sbjct: 966 LLRIFEPI---LGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVLSHQ 1022
Query: 1929 ARLCSQCSENEVAAATAVIGKTAKLEQEMQHLVSICQHCGGGDRLLESGVKCTSISCLVF 1988
+C C E + LE+ L + CQ C G L V CTS C +F
Sbjct: 1023 GAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGS---LHEDVICTSRDCPIF 1079
Query: 1989 YERRKVQKEL 1998
Y R+KV+K+L
Sbjct: 1080 YMRKKVRKDL 1089
Score = 50.4 bits (119), Expect = 5e-05
Identities = 49/182 (26%), Positives = 79/182 (42%), Gaps = 19/182 (10%)
Query: 16 VSVDHYM--ASPIPSIDISHSTFHRGKVNEVPVIRVYGSTPAGQKTCLHIHGALPYLYVS 73
+ +DHY+ A P+P RG V PV+R +G T G C HIHG PY Y
Sbjct: 99 LEIDHYVGPAQPVPG----GPPPSRGSV---PVLRAFGVTDEGFSVCCHIHGFAPYFYTP 151
Query: 74 CSDIPLQLDQEGDAYTYMVASSLEKALKLKGSADSSRQHVHGCSLVRAKKFYGYCSF-EE 132
+ GD + +L + +G + + V L + +GY
Sbjct: 152 APP-GFGPEHMGDLQREL---NLAISRDSRGGRELTGPAVLAVELCSRESMFGYHGHGPS 207
Query: 133 FFVKIYLRYYPQDVSRAANLLLAG----AVLNKSLQPHESHIPFILQFLVDYNLYGMGHL 188
F++I + P+ V+ A LL G + S P+E+++ F ++F+VD ++ G L
Sbjct: 208 PFLRITVA-LPRLVAPARRLLEQGIRVAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWL 266
Query: 189 HL 190
L
Sbjct: 267 EL 268
>DPOD_DROME (P54358) DNA polymerase delta catalytic subunit (EC
2.7.7.7)
Length = 1092
Score = 310 bits (793), Expect = 3e-83
Identities = 243/853 (28%), Positives = 392/853 (45%), Gaps = 87/853 (10%)
Query: 1162 LLSIEVLAESRGDLLPDPQFDAVNIVALGFQKDCDATVEVLVLLHSKFVPCQRSLDGLSD 1221
+LS ++ R + P+ + D V +A +V+ + P R++ L++
Sbjct: 296 ILSFDIECAGRKGIFPEAKIDPVIQIAN------------MVIRQGEREPFIRNVFTLNE 343
Query: 1222 C------KVLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHLGFGLLN 1275
C +VL E +L +++ V DPDIL G+ I +L RA+HL
Sbjct: 344 CAPIIGSQVLCHDKETQMLDKWSAFVREVDPDILTGYNINNFDFPYLLNRAAHLKVRNFE 403
Query: 1276 DLSRTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHVGG 1335
L R IK I +E + + GR V+ G
Sbjct: 404 YLGR-----------IKNIRSVI---------------KEQMLQSKQMGRRENQYVNFEG 437
Query: 1336 RIVLNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYI 1395
R+ +L ++ + KL Y++ AV+ L+ + ++H+++T G Q R + Y
Sbjct: 438 RVPFDLLFVLLRDYKLRSYTLNAVSYHFLQEQKEDVHHSIITD-LQNGDEQTRRRLAMYC 496
Query: 1396 VDRAKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNYVAIS 1455
+ A L L +L +L + E+ARV G+ S+L+RG Q +V S LR A T+ + I
Sbjct: 497 LKDAYLPLRLLEKLMAIVNYMEMARVTGVPLESLLTRGQQIKVLSQLLRKAKTKGF--IM 554
Query: 1456 PGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCT-CLGKVVP 1514
P S E V+EP+ G+Y+DP+ LDF SLYPS+++A+NLC+ T LG
Sbjct: 555 PSYTSQGSDEQYEG-ATVIEPKRGYYADPISTLDFASLYPSIMMAHNLCYTTLVLG---- 609
Query: 1515 SKTNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQ 1574
G + +Q LQD DQ+ TP FV S++RRG+LP +LE +L+ R K
Sbjct: 610 ------GTREKLRQQENLQD--DQVERTPANNYFVKSEVRRGLLPEILESLLAARKRAKN 661
Query: 1575 AMKKLSPSEQVLQRIFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTLE 1634
+K ++ +++ + RQLALK+ +N YG+T A G++PC E++ S+ GR +E
Sbjct: 662 DLK--VETDPFKRKVLDGRQLALKISANSVYGFTGAQV-GKLPCLEISGSVTAYGRTMIE 718
Query: 1635 KAISFVNLH------EKWNAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAITAMNPSP 1688
+ V H + NA VIYGDTDS+ V +T + + ++G E A +++ P
Sbjct: 719 MTKNEVESHYTQANGYENNAVVIYGDTDSVMVNFGVKTLERSMELGREAAELVSSKFVHP 778
Query: 1689 VTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQSLR 1748
+ L+ EKVY+P LI KKRY G + P+ + + D KGIETVRRD VA +M L+
Sbjct: 779 IKLEFEKVYYPYLLINKKRYAGLYFTRPDTYDKM-DCKGIETVRRDNSPLVANLMNSCLQ 837
Query: 1749 LFFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVATKA 1808
+ Y+++ +L R+ + + KE+ Y+A+ + + +A K
Sbjct: 838 KLLIERDPDGAVAYVKQVIADLLCNRIDISHLVITKELAKTDYAAKQAHVE----LAAKM 893
Query: 1809 MRVDRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSPFRINDLYYINKQIIPA 1868
+ D P+ +R+PYV+ DPL VL P I+ YY+ +Q+
Sbjct: 894 KKRDPGTAPKLGDRVPYVICAAAKNTPAYQKAEDPLYVLENSVP--IDATYYLEQQLSKP 951
Query: 1869 LQRVFGLVGADLNQWFAEMPRPVREASVKHAFTPNFQRTRIDYYYLSKHCVLCGGLV--- 1925
L R+F + D + R +V + + C+ C L+
Sbjct: 952 LLRIFEPILGDNAESILLKGEHTRTRTVVTSKVGGL----AGFMTKKTSCLGCKSLMPKG 1007
Query: 1926 QASARLCSQCSENEVAAATAVIGKTAKLEQEMQHLVSICQHCGGGDRLLESGVKCTSISC 1985
A LC C +G +LE+ L + CQ C L V C++ C
Sbjct: 1008 YEQACLCPHCEPRMSELYQKEVGAKRELEETFSRLWTECQRC---QESLHEEVICSNRDC 1064
Query: 1986 LVFYERRKVQKEL 1998
+FY R+KV+ +L
Sbjct: 1065 PIFYMRQKVRMDL 1077
Score = 64.3 bits (155), Expect = 3e-09
Identities = 50/205 (24%), Positives = 98/205 (47%), Gaps = 37/205 (18%)
Query: 16 VSVDHYMASPIPSIDISHSTFHRGKVNEVPVIRVYGSTPAGQKTCLHIHGALPYLYVSCS 75
+ V++Y+ P+P + ++ VPV+R++G T G C H+HG PY Y+
Sbjct: 81 LDVENYLGQPLPGMP-------GAQIGPVPVVRMFGVTMEGNSVCCHVHGFCPYFYI--- 130
Query: 76 DIPLQLDQEGDAYTYMVASSLEKAL------KLKGSADSSRQHVHGCSLVRAKKFYGY-C 128
+ P Q ++ L+KAL ++ + D+ ++ V LV +GY
Sbjct: 131 EAPSQFEEHH-------CEKLQKALDQKVIADIRNNKDNVQEAVLMVELVEKLNIHGYNG 183
Query: 129 SFEEFFVKIYLRYYPQDVSRAANLLLAGAVLN----KSLQPHESHIPFILQFLVDYNLYG 184
++ ++KI + P+ V+ A+ LL +++ + + E++I F ++F+VD ++ G
Sbjct: 184 DKKQRYIKISVT-LPRFVAAASRLLKKEVIMSEIDFQDCRAFENNIDFDIRFMVDTDVVG 242
Query: 185 -------MGHLHLSKMRFRHPMPDS 202
MGH + + P+P+S
Sbjct: 243 CNWIELPMGHWRIRNSHSK-PLPES 266
>DPOD_PLAFK (P30315) DNA polymerase delta catalytic subunit (EC
2.7.7.7)
Length = 1094
Score = 308 bits (789), Expect = 1e-82
Identities = 232/823 (28%), Positives = 388/823 (46%), Gaps = 87/823 (10%)
Query: 1196 DATVEVLVLLHSKFVP---CQRSLDGLSDC------KVLNFTDEKHLLKEFTKIVSSSDP 1246
D +++ +L+ + P C + + L +C V+ F DEK LL+ + + + DP
Sbjct: 325 DPIIQISSILYFQGEPIDNCTKFIFTLLECASIPGSNVIWFNDEKTLLEAWNEFIIRIDP 384
Query: 1247 DILMGWEIQGSSLGFLAERASHLGFGLLNDLSRTPSNSWINSQDIKTSEKSILEPDIPDT 1306
D L G+ I L ++ R + L L L R IK ++
Sbjct: 385 DFLTGYNIINFDLPYILNRGTALNLKKLKFLGR-----------IKNVASTV-------- 425
Query: 1307 TSLDCCARESSIIEDEWGRTHASGVHVGGRIVLNLWRLIRGEVKLNLYSVEAVAEAVLRR 1366
++SS ++G +++ GRI +++ LI+ + KL Y++ V+ L+
Sbjct: 426 -------KDSSFSSKQFGTHETKEINIFGRIQFDVYDLIKRDYKLKSYTLNYVSFEFLKE 478
Query: 1367 KVPSLNHNVLTKWFSRGPGQARYQCIKYIVDRAKLNLEILNQLDMVNRTSELARVFGIDF 1426
+ ++++++ + P ++R + Y + L L ++++L + E+ARV G F
Sbjct: 479 QKEDVHYSIMNDLQNESP-ESRKRIATYCIKDGVLPLRLIDKLLFIYNYVEMARVTGTPF 537
Query: 1427 FSVLSRGSQYRVESMFLRLAHTQNYVAISPGNQQVASQPAMECLPLVMEPESGFYSDPVV 1486
+L+RG Q +V S R NYV I +V + E V+EP G+Y +P+
Sbjct: 538 VYLLTRGQQIKVTSQLYRKCKELNYV-IPSTYMKVNTNEKYEGAT-VLEPIKGYYIEPIS 595
Query: 1487 VLDFQSLYPSMIIAYNLCFCTCLGKVVPSKTNTLGVSPFVPEQHILQDLKDQILLT---P 1543
LDF SLYPS++IA+NLC+ T + K+N H + DL++ + T
Sbjct: 596 TLDFASLYPSIMIAHNLCYSTLI------KSN-----------HEVSDLQNDDITTIQGK 638
Query: 1544 NGVMFVPSKIRRGVLPRLLEEILSTRIMVKQAMKKLSPSEQVLQRIFNARQLALKLISNV 1603
N + FV +++G+LP ++EE++ R VK +K + + + + N RQLALK+ +N
Sbjct: 639 NNLKFVKKNVKKGILPLIVEELIEARKKVKLLIK--NEKNNITKMVLNGRQLALKISANS 696
Query: 1604 TYGYTAAGFSGRMPCAELADSIVQCGRCTLEKAISFV-------NLHEKWNAKVIYGDTD 1656
YGYT A G++PC E+A SI GR +EK V N +E N+ VIYGDTD
Sbjct: 697 VYGYTGASSGGQLPCLEVAVSITTLGRSMIEKTKERVESFYCKSNGYEH-NSTVIYGDTD 755
Query: 1657 SMFVLLKGRTAKEAFQIGSEIASAITAMNPSPVTLKMEKVYHPCFLITKKRYVGYSYENP 1716
S+ V +EA +G + A I+ SP+ L+ EKVY P L+ KKRY G Y NP
Sbjct: 756 SVMVKFGTNNIEEAMTLGKDAAERISKEFLSPIKLEFEKVYCPYLLLNKKRYAGLLYTNP 815
Query: 1717 NQIEPVFDAKGIETVRRDTCEAVAKIMEQSLRLFFEHQSLLEVKTYLQRQWKRILSGRVS 1776
N+ + + D KGIETVRRD C + ++ME L ++L Y + + K +L+ +
Sbjct: 816 NKHDKM-DCKGIETVRRDFCILIQQMMETVLNKLLIEKNLNSAIEYTKSKIKELLTNNID 874
Query: 1777 LKDFIFAKEVRLGTYSARISSLPPAAIVATKAMRVDRRAEPRYAERIPYVVIHGEPGARL 1836
+ + K + Y R+ P +A K + D P +R+ Y+++ G G
Sbjct: 875 MSLLVVTKSLGKTDYETRL----PHVELAKKLKQRDSATAPNVGDRVSYIIVKGVKGQAQ 930
Query: 1837 VDMVVDPLEVLAIDSPFRINDLYYINKQIIPALQRVFGLVGADLNQWFAEMPRPVREASV 1896
+ DPL VL D+ I+ +Y++ I L R+F ++ + + F+ + +
Sbjct: 931 YERAEDPLYVL--DNNLAIDYNHYLD-AIKSPLSRIFEVIMQNSDSLFS------GDHTR 981
Query: 1897 KHAFTPNFQRTRIDYYYLSKHCVLCGGLVQASARLCSQCSEN-EVAAATAVIGKTAKLEQ 1955
+ Q + S C+ C ++ LC+ C EN E + I +
Sbjct: 982 HKTILTSSQTALSKFLKKSVRCIGCNSSIK-KPPLCNHCKENKEFSIYMQKIKDFKNKQN 1040
Query: 1956 EMQHLVSICQHCGGGDRLLESGVKCTSISCLVFYERRKVQKEL 1998
E L + CQ C G L V C + C +FY R K++K++
Sbjct: 1041 EFFQLWTECQRCQGN---LHVDVICMNRDCPIFYRRAKIKKDI 1080
Score = 41.6 bits (96), Expect = 0.023
Identities = 59/278 (21%), Positives = 111/278 (39%), Gaps = 33/278 (11%)
Query: 44 VPVIRVYGSTPAGQKTCLHIHGALPYLYVSCSDIPLQLDQEGDAYTYMVASSLEKALKLK 103
VP+IR+Y G +++H PY YV + P D E M+ + + L L
Sbjct: 116 VPIIRIYSLRKDGCSVLINVHNFFPYFYV---EKPDDFDNEDLIKLEML---MNENLNLN 169
Query: 104 GSADSSRQHVHGCSLVRAKK-FYGYCSFEEFFVKI---------YLRYYPQDVSRAANLL 153
+ + +V+ + Y + ++ F+KI L+ Y + + N
Sbjct: 170 SQYKIYEKKILKIEIVKTESLMYFKKNGKKDFLKITVLLPKMVPSLKKYFEGIVHVNNKS 229
Query: 154 LAGAVLNKSLQPHESHIPFILQFLVDYNLYGMGHLHLSK----MRFRHPMPDSIHKKSDI 209
+ G V +E+++PFIL++++D+ + G ++ K +R ++ + + DI
Sbjct: 230 IGGIV-------YEANLPFILRYIIDHKITGSSWINCKKGHYYIRNKNKKISNCTFEIDI 282
Query: 210 NSQHRKADPGAEACLESKIWMSSTISFDWMWSLPSESGGSSNDNTHSPKRQSICELEGDI 269
+ +H +P +I +SFD G N + SI +G+
Sbjct: 283 SYEH--VEPITLENEYQQIPKLRILSFDIECIKLDGKGFPEAKNDPIIQISSILYFQGE- 339
Query: 270 SVDEILNQQFKMFSSLSQTSSNV---NMVQSLVSIWEE 304
+D F + S SNV N ++L+ W E
Sbjct: 340 PIDNCTKFIFTLLECASIPGSNVIWFNDEKTLLEAWNE 377
>DPOD_YEAST (P15436) DNA polymerase delta catalytic subunit (EC
2.7.7.7) (DNA polymerase III)
Length = 1097
Score = 301 bits (771), Expect = 1e-80
Identities = 236/863 (27%), Positives = 397/863 (45%), Gaps = 106/863 (12%)
Query: 1156 HGQQLALLSIEVLAESRGDLLPDPQFDAV----NIVALGFQKDCDATVEVLVLLHSKFVP 1211
H L ++S ++ R + P+P++D V N+V++ K P
Sbjct: 311 HTAPLRIMSFDIECAGRIGVFPEPEYDPVIQIANVVSIAGAKK----------------P 354
Query: 1212 CQRSLDGLSDCK------VLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAER 1265
R++ L+ C + + E+ +L + + DPD+++G+ + +L R
Sbjct: 355 FIRNVFTLNTCSPITGSMIFSHATEEEMLSNWRNFIIKVDPDVIIGYNTTNFDIPYLLNR 414
Query: 1266 ASHLGFGLLNDLSRTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGR 1325
A L R +KT ++ I +ES +G
Sbjct: 415 AKALKVNDFPYFGR-----------LKTVKQEI---------------KESVFSSKAYGT 448
Query: 1326 THASGVHVGGRIVLNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPG 1385
V++ GR+ L+L + I+ E KL Y++ AV+ L + +++++++ G
Sbjct: 449 RETKNVNIDGRLQLDLLQFIQREYKLRSYTLNAVSAHFLGEQKEDVHYSIISD-LQNGDS 507
Query: 1386 QARYQCIKYIVDRAKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRL 1445
+ R + Y + A L L ++ +L + +E+ARV G+ F +L+RG Q +V S R
Sbjct: 508 ETRRRLAVYCLKDAYLPLRLMEKLMALVNYTEMARVTGVPFSYLLARGQQIKVVSQLFRK 567
Query: 1446 AHTQNYVAISPGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCF 1505
+ V P Q AS E V+EP G+Y P+ LDF SLYPS+++A+NLC+
Sbjct: 568 CLEIDTVI--PNMQSQASDDQYEGAT-VIEPIRGYYDVPIATLDFNSLYPSIMMAHNLCY 624
Query: 1506 CTCLGKVVPSKTNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEI 1565
T K + N + + ++TPNG FV +K RRG+LP +L+E+
Sbjct: 625 TTLCNKATVERLNL--------------KIDEDYVITPNGDYFVTTKRRRGILPIILDEL 670
Query: 1566 LSTRIMVKQAMKKLSPSEQVLQR-IFNARQLALKLISNVTYGYTAAGFSGRMPCAELADS 1624
+S R K+A K L + +R + N RQLALK+ +N YG+T A G++PC ++ S
Sbjct: 671 ISAR---KRAKKDLRDEKDPFKRDVLNGRQLALKISANSVYGFTGATV-GKLPCLAISSS 726
Query: 1625 IVQCGRCTLEKAISFVNLHE------KWNAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIA 1678
+ GR + K + V K +A V+YGDTDS+ V KEA +G+E A
Sbjct: 727 VTAYGRTMILKTKTAVQEKYCIKNGYKHDAVVVYGDTDSVMVKFGTTDLKEAMDLGTEAA 786
Query: 1679 SAITAMNPSPVTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEA 1738
++ + P+ L+ EK Y P LI KKRY G + NP++ + + D KG+ +VRRD+C
Sbjct: 787 KYVSTLFKHPINLEFEKAYFPYLLINKKRYAGLFWTNPDKFDKL-DQKGLASVRRDSCSL 845
Query: 1739 VAKIMEQSLRLFFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSL 1798
V+ +M + L+ +++ +++ IL RV + I +K T + ++
Sbjct: 846 VSIVMNKVLKKILIERNVDGALAFVRETINDILHNRVDISKLIISK-----TLAPNYTNP 900
Query: 1799 PPAAIVATKAMRVDRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSPFRINDL 1858
P A++A + M+ P +R+ YV+I G +L + DPL VL ++ +++
Sbjct: 901 QPHAVLAER-MKRREGVGPNVGDRVDYVIIGGND--KLYNRAEDPLFVL--ENNIQVDSR 955
Query: 1859 YYINKQI-IPALQRVFGLVG-ADLNQWFAEMPRPVREASVKHAFTPNFQRTRIDYYYLSK 1916
YY+ Q+ P + V ++G N F + S K ++ +
Sbjct: 956 YYLTNQLQNPIISIVAPIIGDKQANGMFVVKSIKINTGSQKGGLMSFIKKV--------E 1007
Query: 1917 HCVLC-GGLVQASARLCSQCSENEVAAATAVIGKTAKLEQEMQHLVSICQHCGGGDRLLE 1975
C C G L + LCS C + LE++ L + CQ C G L
Sbjct: 1008 ACKSCKGPLRKGEGPLCSNCLARSGELYIKALYDVRDLEEKYSRLWTQCQRCAGN---LH 1064
Query: 1976 SGVKCTSISCLVFYERRKVQKEL 1998
S V C++ +C +FY R KV+KEL
Sbjct: 1065 SEVLCSNKNCDIFYMRVKVKKEL 1087
>DPOD_CANAL (P46588) DNA polymerase delta catalytic subunit (EC
2.7.7.7) (DNA polymerase III)
Length = 1038
Score = 298 bits (762), Expect = 1e-79
Identities = 230/858 (26%), Positives = 400/858 (45%), Gaps = 97/858 (11%)
Query: 1160 LALLSIEVLAESRGDLLPDPQFDAVNIVALGFQKDCDATVEVLVLLHSKFVPCQRSLDGL 1219
L +LS ++ R + P+ + D V +A QK ++ V + V + +
Sbjct: 244 LRILSFDIECAGRKGVFPEAEHDPVIQIANVVQKSGESKPFV------RNVFTVNTCSSI 297
Query: 1220 SDCKVLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHLG------FGL 1273
++ E+ +L + + ++ DPD+++G+ + ++ RA LG FG
Sbjct: 298 IGSQIFEHQREEDMLMHWKEFITKVDPDVIIGYNTANFDIPYVLNRAKALGLNDFPFFGR 357
Query: 1274 LNDLSRTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHV 1333
L + + ++ +S+ T E + V++
Sbjct: 358 LKRVKQEIKDAVFSSRAYGTRENKV--------------------------------VNI 385
Query: 1334 GGRIVLNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIK 1393
GR+ L+L + I+ E KL Y++ +V+ L + + H+++T G + R +
Sbjct: 386 DGRMQLDLLQFIQREYKLRSYTLNSVSAHFLGEQKEDVQHSIITD-LQNGTKETRRRLAV 444
Query: 1394 YIVDRAKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNYVA 1453
Y + A L L +L++L + +E+ARV G+ F +LSRG Q +V S R ++ V
Sbjct: 445 YCLKDAFLPLRLLDKLMCLVNYTEMARVTGVPFSYLLSRGQQIKVISQLFRKCLQEDIVI 504
Query: 1454 ISPGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLGKVV 1513
P + S E V+EPE G+Y P+ LDF SLYPS+++A+NLC+ T L K
Sbjct: 505 --PNLKSEGSNEEYEGAT-VIEPERGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLNK-- 559
Query: 1514 PSKTNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVK 1573
+ G++ +D TPNG FV S +R+G+LP +L+E+L+ R K
Sbjct: 560 -NSIKAFGLT------------EDDYTKTPNGDYFVHSNLRKGILPTILDELLTARKKAK 606
Query: 1574 QAMKKLSPSEQVLQRIFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTL 1633
+KK ++ + + N RQLALK+ +N YG+T A G++PC ++ S+ GR +
Sbjct: 607 ADLKK--ETDPFKKDVLNGRQLALKISANSVYGFTGATV-GKLPCLAISSSVTAFGREMI 663
Query: 1634 EKAISFVNLH------EKWNAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAITAMNPS 1687
EK + V + ++AKVIYGDTDS+ V + + ++G E A+ ++ +
Sbjct: 664 EKTKNEVQEYYSKKNGHPYDAKVIYGDTDSVMVKFGYQDLETCMKLGEEAANYVSTKFKN 723
Query: 1688 PVTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQSL 1747
P+ L+ EKVY P LI KKRY G + P + + + D KGIETVRRD C V ++ + L
Sbjct: 724 PIKLEFEKVYFPYLLINKKRYAGLYWTRPEKFDKM-DTKGIETVRRDNCRLVQNVITKVL 782
Query: 1748 RLFFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVATK 1807
E + + + + ++++ +L R+ L + K YSA+ + + +A +
Sbjct: 783 EFILEERDVPKAQRFVKQTIADLLQNRIDLSQLVITKAYSKHDYSAKQAHVE----LAER 838
Query: 1808 AMRVDRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSPFRINDLYYINKQIIP 1867
+ D + P +R+ YV+I G + + DPL VL P + YY+++Q+
Sbjct: 839 MRKRDPGSAPTLGDRVAYVIIK-TGGDKNYEKSEDPLYVLENSLPIDVK--YYLDQQLTK 895
Query: 1868 ALQRVF-GLVGADLNQWF--AEMPRPVREASVKHAFTPNFQRTRIDYYYLSKHCVLCGGL 1924
L+R+F ++G + R ++ A+ K F + S+ CV C
Sbjct: 896 PLERIFIPILGETKTKELLTGSHTRTIKVAAPKTGGLLRFAKK-------SEVCVSCRTP 948
Query: 1925 VQAS--ARLCSQCSENEVAAAT--AVIGKTAKLEQEMQHLVSICQHCGGGDRLLESGVKC 1980
++ LC C ++ + + LE + L + CQ C G L V C
Sbjct: 949 LKKDNLGALCPNCIKDGKGPDLYGNALSQMNYLENKFSRLWTECQRCQGS---LHQEVLC 1005
Query: 1981 TSISCLVFYERRKVQKEL 1998
++ C +FY R K QK++
Sbjct: 1006 SNKDCPIFYMRTKAQKDV 1023
>DPOD_SOYBN (O48901) DNA polymerase delta catalytic subunit (EC
2.7.7.7)
Length = 1088
Score = 293 bits (750), Expect = 3e-78
Identities = 216/727 (29%), Positives = 346/727 (46%), Gaps = 82/727 (11%)
Query: 1162 LLSIEVLAESRGDLLPDPQFDAVNIVALGFQKDCDATVEVLVLLHSKFVPCQRSLDGLSD 1221
+LS ++ R P+P D V +A LV L + P R++ L
Sbjct: 273 ILSFDIECAGRKGHFPEPTHDPVIQIAN------------LVTLQGEDQPFIRNVMTLKS 320
Query: 1222 CK------VLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHLGFGLLN 1275
C V+ F E+ +L + + DPDI++G+ I L +L ERA +L
Sbjct: 321 CSPIVGVDVMPFETEREVLLAWRDFIREVDPDIIIGYNICKFDLPYLIERALNLKIAEFP 380
Query: 1276 DLSRTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHVGG 1335
L R NS + +D S + ++G + V V G
Sbjct: 381 ILGRI-RNSRVRVKDTTFSSR-------------------------QYGTRESKEVAVEG 414
Query: 1336 RIVLNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYI 1395
R+ +L ++++ + KL+ YS+ +V+ L + ++H++++ G + R + Y
Sbjct: 415 RVTFDLLQVMQRDYKLSSYSLNSVSSHFLSEQKEDVHHSIISD-LQNGNAETRRRLAVYC 473
Query: 1396 VDRAKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNYVAIS 1455
+ A L +L++L + E+ARV G+ +LSRG +V S LR A +N V
Sbjct: 474 LKDAYLPQRLLDKLMFIYNYVEMARVTGVPISFLLSRGQSIKVLSQLLRRARQKNLVI-- 531
Query: 1456 PGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLGKVVPS 1515
P +Q S+ V+E +GFY P+ LDF SLYPS+++AYNLC+CT V+P
Sbjct: 532 PNAKQAGSEQGTFEGATVLEARAGFYEKPIATLDFASLYPSIMMAYNLCYCTL---VIPE 588
Query: 1516 KTNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQA 1575
L + P + + TP+G FV S +++G+LP +LEE+L+ R K+A
Sbjct: 589 DARKLNIPP------------ESVNRTPSGETFVKSNLQKGILPEILEELLTAR---KRA 633
Query: 1576 MKKLSPSEQVLQR-IFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTLE 1634
L ++ L++ + + RQLALK+ +N YG+T A G++PC E++ S+ GR +E
Sbjct: 634 KADLKEAKDPLEKAVLDGRQLALKISANSVYGFTGATI-GQLPCLEISSSVTSYGRQMIE 692
Query: 1635 KAISFV-------NLHEKWNAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAITAMNPS 1687
V N +E NA+VIYGDTDS+ V +EA +G E A I+
Sbjct: 693 HTKKLVEDKFTTLNGYEH-NAEVIYGDTDSVMVQFGVSAVEEAMNLGREAAEHISGTFTK 751
Query: 1688 PVTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQSL 1747
P+ L+ EKVY+P LI+KKRY G + P+ + + D KGIETVRRD C V ++ L
Sbjct: 752 PIKLEFEKVYYPYLLISKKRYAGLFWTKPDNFDKM-DTKGIETVRRDNCLLVKNLVNDCL 810
Query: 1748 RLFFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVATK 1807
+ + Y++ +L R+ L + K + T + + A + +
Sbjct: 811 HKILIDRDIPGAVQYVKNAISDLLMNRMDLSLLVITKGL---TKTGDDYEVKAAHVELAE 867
Query: 1808 AMRV-DRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSPFRINDLYYINKQII 1866
MR D P +R+PYV+I GA+ + DP+ VL + P I+ YY+ QI
Sbjct: 868 RMRKRDAATAPNVGDRVPYVIIKAAKGAKAYERSEDPIYVLENNIP--IDPHYYLENQIS 925
Query: 1867 PALQRVF 1873
+ R+F
Sbjct: 926 KPILRIF 932
Score = 50.8 bits (120), Expect = 4e-05
Identities = 40/158 (25%), Positives = 72/158 (45%), Gaps = 12/158 (7%)
Query: 32 SHSTFHRGKVNEVPVIRVYGSTPAGQKTCLHIHGALPYLYVSCSDIPLQLDQEGDAYTYM 91
SH V +IR++G T G C ++HG PY Y+ C P + + ++ +
Sbjct: 74 SHGELLPNSSGPVAIIRIFGVTKEGHSVCCNVHGFEPYFYICC---PPGMGPDDISHFH- 129
Query: 92 VASSLEKALKLKGSADSSRQHVHGCSLVRAKK-FYGYCSFEEFFVKIYLRYYPQDVSRAA 150
+LE ++ + + V +V+ + Y S + F+KI + P V+
Sbjct: 130 --QTLEGRMREANRNSNVGKFVRRIEMVQRRSIMYYQQSNSQPFLKIVVA-LPTMVASCR 186
Query: 151 NLLLAGAVLN----KSLQPHESHIPFILQFLVDYNLYG 184
+L G L+ KS +ES++ F L+F++D N+ G
Sbjct: 187 GILDRGIQLDGLGMKSFLTYESNVLFALRFMIDCNIVG 224
>DPOD_SCHPO (P30316) DNA polymerase delta catalytic subunit (EC
2.7.7.7) (DNA polymerase III)
Length = 1086
Score = 291 bits (744), Expect = 2e-77
Identities = 227/849 (26%), Positives = 394/849 (45%), Gaps = 81/849 (9%)
Query: 1160 LALLSIEVLAESRGDLLPDPQFDAVNIVALGFQKDCDATVEVLVLLHSKFVPCQRSLDGL 1219
L ++S ++ R + PDP D V +A + D+T V + V C + +
Sbjct: 294 LRIMSFDIECAGRKGVFPDPSIDPVIQIASIVTQYGDSTPFV------RNVFCVDTCSQI 347
Query: 1220 SDCKVLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHL---GFGLLND 1276
+V F ++ +L ++K V DPD+L+G+ I + +L +RA L F LL
Sbjct: 348 VGTQVYEFQNQAEMLSSWSKFVRDVDPDVLIGYNICNFDIPYLLDRAKSLRIHNFPLLGR 407
Query: 1277 LSRTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHVGGR 1336
+ S A+E++ +G + + GR
Sbjct: 408 IHNFFS-----------------------------VAKETTFSSKAYGTRESKTTSIPGR 438
Query: 1337 IVLNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYIV 1396
+ L++ ++++ + KL YS+ AV L + ++++++T G +R + Y +
Sbjct: 439 LQLDMLQVMQRDFKLRSYSLNAVCSQFLGEQKEDVHYSIITD-LQNGTADSRRRLAIYCL 497
Query: 1397 DRAKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNYVAISP 1456
A L ++++L +E+ARV G+ F +L+RG Q +V S R A + V
Sbjct: 498 KDAYLPQRLMDKLMCFVNYTEMARVTGVPFNFLLARGQQIKVISQLFRKALQHDLVV--- 554
Query: 1457 GNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLGKVVPSK 1516
N +V V+EP G+Y P+ LDF SLYPS++ A+NLC+ T L
Sbjct: 555 PNIRVNGTDEQYEGATVIEPIKGYYDTPIATLDFSSLYPSIMQAHNLCYTTLLD------ 608
Query: 1517 TNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQAM 1576
+NT + + QD+ + TPNG FV +R+G+LP +L ++L+ R K +
Sbjct: 609 SNTAELLK------LKQDVDYSV--TPNGDYFVKPHVRKGLLPIILADLLNARKKAKADL 660
Query: 1577 KKLSPSEQVLQRIFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTLEKA 1636
KK ++ + + + RQLALK+ +N YG+T A +GR+PC ++ S+ GR +EK
Sbjct: 661 KK--ETDPFKKAVLDGRQLALKVSANSVYGFTGAT-NGRLPCLAISSSVTSYGRQMIEKT 717
Query: 1637 ISFVNLHEK------WNAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAITAMNPSPVT 1690
V + +A VIYGDTDS+ V +T EA ++G E A+ ++ P+P+
Sbjct: 718 KDVVEKRYRIENGYSHDAVVIYGDTDSVMVKFGVKTLPEAMKLGEEAANYVSDQFPNPIK 777
Query: 1691 LKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQSLRLF 1750
L+ EKVY P LI+KKRY G + + + + D+KGIETVRRD C V+ +++ +LR
Sbjct: 778 LEFEKVYFPYLLISKKRYAGLFWTRTDTYDKM-DSKGIETVRRDNCPLVSYVIDTALRKM 836
Query: 1751 FEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVATKAMR 1810
Q + + + ++ +L ++ + + K + Y+A+++ + +A + +
Sbjct: 837 LIDQDVEGAQLFTKKVISDLLQNKIDMSQLVITKALSKTDYAAKMAHVE----LAERMRK 892
Query: 1811 VDRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSPFRINDLYYINKQIIPALQ 1870
D + P +R+ YV+I G G + DP+ VL + P I+ YY+ Q+ L
Sbjct: 893 RDAGSAPAIGDRVAYVIIKGAQGDQFYMRSEDPIYVLENNIP--IDAKYYLENQLSKPLL 950
Query: 1871 RVFGLVGADLNQWFAEMPRPVREASVKHAFTPNFQRTRIDYYYLSKHCVLC-GGLVQASA 1929
R+F + L + + + ++ A P+ + + + C+ C + +
Sbjct: 951 RIFEPI---LGEKASSLLHGDHTRTISMA-APSVGGI-MKFAVKVETCLGCKAPIKKGKT 1005
Query: 1930 RLCSQCSENEVAAATAVIGKTAKLEQEMQHLVSICQHCGGGDRLLESGVKCTSISCLVFY 1989
LC C + + LE L + CQ C G + V CTS C +FY
Sbjct: 1006 ALCENCLNRSAELYQRQVAQVNDLEVRFARLWTQCQRCQGS---MHQDVICTSRDCPIFY 1062
Query: 1990 ERRKVQKEL 1998
R K+L
Sbjct: 1063 MRIAEHKKL 1071
Score = 51.6 bits (122), Expect = 2e-05
Identities = 45/165 (27%), Positives = 78/165 (47%), Gaps = 27/165 (16%)
Query: 44 VPVIRVYGSTPAGQKTCLHIHGALPYLYVSCSDIPLQLDQEG-DAYTYMVASSLEKALKL 102
VP IR++G T G +H+ G LPY YV P+ E + +T + ++ +
Sbjct: 113 VPSIRLFGVTDNGNSILVHVVGFLPYFYVKA---PVGFRPEMLERFTQDLDATCNGGV-- 167
Query: 103 KGSADSSRQHVHGCSLVRAKKFYGYCSFEEF-FVKIYLRYYPQDVSRAANLLLAGAVLNK 161
+ C + + YG+ E+ F+KI+ P+ +SRA N+ G +
Sbjct: 168 ----------IDHCIIEMKENLYGFQGNEKSPFIKIFTTN-PRILSRARNVFERGEFNFE 216
Query: 162 SLQP-------HESHIPFILQFLVDYNLYGMGHLHL--SKMRFRH 197
L P ES+ ++L+F++D ++ GM +HL SK +FR+
Sbjct: 217 ELFPVGVGVTTFESNTQYLLRFMIDCDVVGMNWIHLPASKYQFRY 261
>DPOD_CAEEL (P90829) DNA polymerase delta catalytic subunit (EC
2.7.7.7)
Length = 1081
Score = 290 bits (742), Expect = 3e-77
Identities = 217/836 (25%), Positives = 381/836 (44%), Gaps = 93/836 (11%)
Query: 1193 KDCDATVEVLVLLHSKFVPCQRSLDGLSDC------KVLNFTDEKHLLKEFTKIVSSSDP 1246
KD + LV + + P R+ L C ++ +EK LL+++ + V DP
Sbjct: 301 KDPIIQIANLVKIEGEAEPFVRNCFVLGTCAPVVGSNIIQCVNEKVLLEKWAEFVREVDP 360
Query: 1247 DILMGWEIQGSSLGFLAERASHLGFGLLNDLSRTPSNSWINSQDIKTSEKSILEPDIPDT 1306
DI+ G+ I L ++ +RA L ++ L R +
Sbjct: 361 DIITGYNILNFDLPYILDRAKVLSLPQVSHLGRQKEKGSV-------------------- 400
Query: 1307 TSLDCCARESSIIEDEWGRTHASGVHVGGRIVLNLWRLIRGEVKLNLYSVEAVAEAVLRR 1366
R+++I + G + + GRI+ ++ +++ + KL Y++ +V+ L
Sbjct: 401 ------VRDAAISSKQMGSRVNKSIDIHGRIIFDVLQVVLRDYKLRSYTLNSVSYQFLSE 454
Query: 1367 KVPSLNHNVLTKWFSRGPGQARYQCIKYIVDRAKLNLEILNQLDMVNRTSELARVFGIDF 1426
+ + HN++ RG Q R + +Y + A L L +L++L + E+ARV G+
Sbjct: 455 QKEDVEHNIIPD-LQRGDEQTRRRLAQYCLKDAYLPLRLLDKLMSIINYIEMARVTGVPM 513
Query: 1427 FSVLSRGSQYRVESMFLRLAHTQNY----VAISPGNQQVASQPAMECLPLVMEPESGFYS 1482
+L++G Q ++ SM LR N+ + + G+ + V++P GFY+
Sbjct: 514 NFLLTKGQQIKILSMMLRRCKQNNFFLPVIEANSGDGEGYEGAT------VIDPIRGFYN 567
Query: 1483 DPVVVLDFQSLYPSMIIAYNLCFCTCLGKVVPSKTNTLGVSPFVPEQHILQDLKDQILLT 1542
+P+ LDF SLYPS++IA+NLC+ T L + GV + + T
Sbjct: 568 EPIATLDFASLYPSIMIAHNLCYTTLL-------KSPQGVE------------NEDYIRT 608
Query: 1543 PNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQAMKKLSPSEQVLQRIFNARQLALKLISN 1602
P+G F RRG+LP +LE+IL+ R K MK + ++ + ++N RQLALK+ +N
Sbjct: 609 PSGQYFATKSKRRGLLPEILEDILAARKRAKNDMK--NEKDEFKRMVYNGRQLALKISAN 666
Query: 1603 VTYGYTAAGFSGRMPCAELADSIVQCGRCTLEKA-ISFVNLHEKW--------NAKVIYG 1653
YG+T A G++PC E++ S+ GR ++ + +++K +AKVIYG
Sbjct: 667 SVYGFTGATV-GKLPCLEISQSVTAFGRKMIDMTKLEVERIYKKGALDGKCPADAKVIYG 725
Query: 1654 DTDSMFVLLKGRTAKEAFQIGSEIASAITAMNPSPVTLKMEKVYHPCFLITKKRYVGYSY 1713
DTDS+ V T +A +IG + A ++ + P+ L+ EKVY P LI KKRY G +
Sbjct: 726 DTDSVMVKFGVETVAQAMEIGLDAAKEVSKIFTPPIKLEFEKVYSPYLLINKKRYAGLYF 785
Query: 1714 ENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQSLRLFFEHQSLLEVKTYLQRQWKRILSG 1773
P+ + D KG+ETVRRD C VAK++ L + + +R +L
Sbjct: 786 TKPD-VHDKMDCKGLETVRRDNCPLVAKVLGVCLEKLLIERDQQSALDFAKRTISDLLCN 844
Query: 1774 RVSLKDFIFAKEVRLG--TYSARISSLPPAAIVATKAMRVDRRAEPRYAERIPYVVIHGE 1831
++ + I +KE+ Y A+ + + +A + + D + PR +R+PYV +
Sbjct: 845 KIDISLLIISKELTKSGDKYQAKQAHVE----LAARMKKRDAGSAPRLGDRVPYVFVAAA 900
Query: 1832 PGARLVDMVVDPLEVLAIDSPFRINDLYYINKQIIPALQRVFGLVGADLNQWFAEMPRPV 1891
+ DP VL + P ++ +Y+ Q+ L R+F + D +
Sbjct: 901 KNVPAYERAEDPTFVLQNNIP--LDTKHYLTNQLAKPLARIFEPILGDRAEKILVEGEHT 958
Query: 1892 REASVKHAFTPNFQRTRIDYYYLSKHCVLCGGLV---QASARLCSQCSENEVAAATAVIG 1948
R +V + + S C+ C ++ ++ +C C + +
Sbjct: 959 RVRTVVQSKVGGLAA----FTTKSATCLGCKSVLPRAESENAVCKHCEPKLPTIFASRMN 1014
Query: 1949 KTAKLEQEMQHLVSICQHCGGGDRLLESGVKCTSISCLVFYERRKVQKELLAATHV 2004
+LE L + CQ+C + ++ V C++ C ++Y R KV+ EL A+ V
Sbjct: 1015 TMHELENHFGRLWTECQNCA---KTMQDKVNCSARDCPIYYMREKVRNELSEASAV 1067
>DPOD_ARATH (Q9LVN7) DNA polymerase delta catalytic subunit (EC
2.7.7.7)
Length = 1081
Score = 283 bits (724), Expect = 3e-75
Identities = 211/725 (29%), Positives = 340/725 (46%), Gaps = 78/725 (10%)
Query: 1162 LLSIEVLAESRGDLLPDPQFDAVNIVALGFQKDCDATVEVLVLLHSKFVPCQRSLDGLSD 1221
+LS ++ R P+ + D V +A LV L + P R++ L
Sbjct: 306 VLSFDIECAGRKGHFPEAKHDPVIQIAN------------LVTLQGEDHPFVRNVMTLKS 353
Query: 1222 CK------VLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHLGFGLLN 1275
C V++F E+ +L + ++ DPDI++G+ I L +L ERA+ LG
Sbjct: 354 CAPIVGVDVMSFETEREVLLAWRDLIRDVDPDIIIGYNICKFDLPYLIERAATLGIEEFP 413
Query: 1276 DLSRTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHVGG 1335
L R +K S + R+S+ + G + + G
Sbjct: 414 LLGR-----------VKNSRVRV---------------RDSTFSSRQQGIRESKETTIEG 447
Query: 1336 RIVLNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYI 1395
R +L + I + KL+ YS+ +V+ L + ++H+++T G + R + Y
Sbjct: 448 RFQFDLIQAIHRDHKLSSYSLNSVSAHFLSEQKEDVHHSIITD-LQNGNAETRRRLAVYC 506
Query: 1396 VDRAKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNYVAIS 1455
+ A L +L++L + E+ARV G+ +L+RG +V S LR +N V
Sbjct: 507 LKDAYLPQRLLDKLMFIYNYVEMARVTGVPISFLLARGQSIKVLSQLLRKGKQKNLVL-- 564
Query: 1456 PGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLGKVVPS 1515
P +Q S+ V+E +GFY P+ LDF SLYPS+++AYNLC+CT V P
Sbjct: 565 PNAKQSGSEQGTYEGATVLEARTGFYEKPIATLDFASLYPSIMMAYNLCYCTL---VTPE 621
Query: 1516 KTNTLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQA 1575
L + P + + TP+G FV +++G+LP +LEE+L+ R K+A
Sbjct: 622 DVRKLNLPP------------EHVTKTPSGETFVKQTLQKGILPEILEELLTAR---KRA 666
Query: 1576 MKKLSPSEQVLQR-IFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTLE 1634
L ++ L++ + + RQLALK+ +N YG+T A G++PC E++ S+ GR +E
Sbjct: 667 KADLKEAKDPLEKAVLDGRQLALKISANSVYGFTGATV-GQLPCLEISSSVTSYGRQMIE 725
Query: 1635 KAISFVNLH------EKWNAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAITAMNPSP 1688
+ V ++NA+VIYGDTDS+ V + A +G E A I+ P
Sbjct: 726 QTKKLVEDKFTTLGGYQYNAEVIYGDTDSVMVQFGVSDVEAAMTLGREAAEHISGTFIKP 785
Query: 1689 VTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVAKIMEQSLR 1748
+ L+ EKVY P LI KKRY G + NP Q + + D KGIETVRRD C V ++ +SL
Sbjct: 786 IKLEFEKVYFPYLLINKKRYAGLLWTNPQQFDKM-DTKGIETVRRDNCLLVKNLVTESLN 844
Query: 1749 LFFEHQSLLEVKTYLQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVATKA 1808
+ + +++ +L R+ L + K + + S +A +
Sbjct: 845 KILIDRDVPGAAENVKKTISDLLMNRIDLSLLVITKGLTKTGDDYEVKS--AHGELAERM 902
Query: 1809 MRVDRRAEPRYAERIPYVVIHGEPGARLVDMVVDPLEVLAIDSPFRINDLYYINKQIIPA 1868
+ D P +R+PYV+I GA+ + DP+ VL + P I+ YY+ QI
Sbjct: 903 RKRDAATAPNVGDRVPYVIIKAAKGAKAYERSEDPIYVLQNNIP--IDPNYYLENQISKP 960
Query: 1869 LQRVF 1873
L R+F
Sbjct: 961 LLRIF 965
Score = 56.2 bits (134), Expect = 9e-07
Identities = 48/184 (26%), Positives = 84/184 (45%), Gaps = 21/184 (11%)
Query: 6 SNSDVFSVRIVSVDHYMASPIPSIDISHSTFHRGKVNEVPVIRVYGSTPAGQKTCLHIHG 65
SNS +F + +D +A SH G + P+IR++G T G C +HG
Sbjct: 90 SNSQIFQQ--LEIDSIIAE-------SHKELLPGSSGQAPIIRMFGVTREGNSVCCFVHG 140
Query: 66 ALPYLYVSCSDIPLQLDQEGDAYTYMVASSLEKALKLKGSADSSRQHVHGCSLVRAKKFY 125
PY Y++C P + + + + SLE ++ + V +V+ +
Sbjct: 141 FEPYFYIAC---PPGMGPDDISNFH---QSLEGRMRESNKNAKVPKFVKRIEMVQKRSIM 194
Query: 126 GYCSFE-EFFVKIYLRYYPQDVSRAANLLLAGAVLN----KSLQPHESHIPFILQFLVDY 180
Y + + F+KI + P V+ +L G ++ KS Q +ES+I F+L+F+VD
Sbjct: 195 YYQQQKSQTFLKITVA-LPTMVASCRGILDRGLQIDGLGMKSFQTYESNILFVLRFMVDC 253
Query: 181 NLYG 184
++ G
Sbjct: 254 DIVG 257
>DPOL_EBV (P03198) DNA polymerase (EC 2.7.7.7)
Length = 1015
Score = 184 bits (466), Expect = 3e-45
Identities = 160/567 (28%), Positives = 261/567 (45%), Gaps = 87/567 (15%)
Query: 1331 VHVGGRIVLNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQ 1390
V + G I ++++ + R ++ L+ Y ++ VA +L K +++ + + F+ GP + R +
Sbjct: 431 VRITGLIPIDMYAVCRDKLSLSDYKLDTVARHLLGAKKEDVHYKEIPRLFAAGP-EGRRR 489
Query: 1391 CIKYIVDRAKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQN 1450
Y V + L +++LN + +E+A++ I VL G Q RV S L A +N
Sbjct: 490 LGMYCVQDSALVMDLLNHFVIHVEVAEIAKIAHIPCRRVLDDGQQIRVFSCLLAAAQKEN 549
Query: 1451 YVAISPGNQQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLG 1510
++ P AS V++P SGFY+ PV+V+DF SLYPS+I A+NLC+ T
Sbjct: 550 FILPMPS----ASDRDGYQGATVIQPLSGFYNSPVLVVDFASLYPSIIQAHNLCYST--- 602
Query: 1511 KVVPSKTNTLGVSPFVPEQHILQDLK-----DQILLTPNGVMFVPSKIRRGVLPRLLEEI 1565
+ P E+H L L+ + LT FV + L LL
Sbjct: 603 MITPG------------EEHRLAGLRPGEDYESFRLTGGVYHFVKKHVHESFLASLLTSW 650
Query: 1566 LSTRIMVKQAMKKLSPSEQVLQR-IFNARQLALKLISNVTYGYTAAGFSGRMPCAELADS 1624
L+ R +K K L+ E QR I + +QLA+K N YG+T +G PC +A++
Sbjct: 651 LAKRKAIK---KLLAACEDPRQRTILDKQQLAIKCTCNAVYGFTGVA-NGLFPCLSIAET 706
Query: 1625 IVQCGRCTLEKAISFVN-------------------LHEKWNAKVIYGDTDSMFVLLKGR 1665
+ GR LE+A +FV L+ + +VIYGDTDS+F+ +G
Sbjct: 707 VTLQGRTMLERAKAFVEALSPANLQALAPSPDAWAPLNPEGQLRVIYGDTDSLFIECRGF 766
Query: 1666 TAKEAFQIGSEIASAIT-AMNPSPVTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFD 1724
+ E + +A+ T ++ +P++L+ EK + LITKKRYVG + +
Sbjct: 767 SESETLRFADALAAHTTRSLFVAPISLEAEKTFSCLMLITKKRYVGVLTDGKTLM----- 821
Query: 1725 AKGIETVRRDTCEAVAKIMEQSLRLFF------EHQSLLEVKTY---------------- 1762
KG+E VR+ C+ V + L L E SLL + +
Sbjct: 822 -KGVELVRKTACKFVQTRCRRVLDLVLADARVKEAASLLSHRPFQESFTQGLPVGFLPVI 880
Query: 1763 --LQRQWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVATKAMRVDRRAE-PRY 1819
L + + + GRV + + F+ E+ + + + +P A+ V+R E P+
Sbjct: 881 DILNQAYTDLREGRVPMGELCFSTELSRKLSAYKSTQMPHLAVY---QKFVERNEELPQI 937
Query: 1820 AERIPYVVIH---GEPGARLVDMVVDP 1843
+RI YV + G GAR +M DP
Sbjct: 938 HDRIQYVFVEPKGGVKGARKTEMAEDP 964
>DPOL_RHCM6 (O71121) DNA polymerase (EC 2.7.7.7)
Length = 1035
Score = 180 bits (456), Expect = 4e-44
Identities = 162/599 (27%), Positives = 266/599 (44%), Gaps = 77/599 (12%)
Query: 1326 THASGVHVGGRIVLNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPG 1385
T + V + G +V++++ + + Y + +AE L+++ +++ + F G
Sbjct: 427 TTTTKVFISGTVVIDMYPVCMAKTSSPNYKLNTMAELYLKQQKEDMSYKDIPVKFISGC- 485
Query: 1386 QARYQCIKYIVDRAKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRL 1445
+ R Q KY V A L ++ N ++ +AR+ I V+ G Q R+ + L
Sbjct: 486 EGRAQVGKYCVQDAVLVKDLFNTINFHYEAGAIARLARIPMRRVIFDGQQIRIYTSLLDE 545
Query: 1446 AHTQNYVAISPGNQQVASQPAMECLP--LVMEPESGFYSDPVVVLDFQSLYPSMIIAYNL 1503
++++ + +S+P V EPE G+YSDPVVV DF SLYPS+I+A+NL
Sbjct: 546 CACRDFIMPNHKGADNSSEPTDVSYQGATVFEPEVGYYSDPVVVFDFASLYPSIIMAHNL 605
Query: 1504 CFCTCLGKVVPSKTNTLGVSPFVPEQHILQ-DLKDQILLTPNGVMFVPSKIRRGVLPRLL 1562
C+ T V P G SP PE +L +L+ + FV + +R VL LL
Sbjct: 606 CYSTF---VAPG-----GESP--PESDVLTVELESGL-----SYRFVKNTVRNSVLSELL 650
Query: 1563 EEILSTRIMVKQAMKKLSPSEQVLQRIFNARQLALKLISNVTYGYTAAGFSGRMPCAELA 1622
+ +S R V++ M+ S + V + + + QLALK+ N YG+T +G MPC +A
Sbjct: 651 TKWVSQRRAVRETMR--SCHDPVKRMLLDKEQLALKVTCNAFYGFTGV-VNGMMPCLPIA 707
Query: 1623 DSIVQCGRCTLEKAISFVN--------LHEKWN----------AKVIYGDTDSMFVLLKG 1664
SI + GR L + FV LH +N KVIYGDTDS+FV +G
Sbjct: 708 ASITRIGRDMLMRTSQFVEENFAEPCFLHNFFNREDYSGDPVAVKVIYGDTDSVFVCYRG 767
Query: 1665 RTAKEAFQIGSEIASAIT-AMNPSPVTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVF 1723
TA + G +A IT + P+ L+ EKV+ +I KKRY+G E
Sbjct: 768 VTAAALIERGPSLAHYITQCLFVDPIKLEFEKVFGSLMMICKKRYIGKIVG-----ETEL 822
Query: 1724 DAKGIETVRRDTCEAVAKIMEQSLRLFFEHQSLLEVKTYLQR------------------ 1765
KG++ VR+ +CE V + ++L F+ + L R
Sbjct: 823 SMKGVDLVRKTSCEFVKNVTRDIIQLLFDDPEVSRAAVQLSRLTLDELKMQGVPPGFGRV 882
Query: 1766 ------QWKRILSGRVSLKDFIFAKEVRLGTYSARISSLPPAAIVATKAMRVDRRAEPRY 1819
+ + R +++ + + + + S+LP A++ A R + P
Sbjct: 883 IQRLSQARDELYTSRARVEELVLSSVLSKDVSLYKQSNLPHIAVIKRLAARSEEL--PVV 940
Query: 1820 AERIPYVV---IHG-EPGARLVDMVVDPLEVLAIDSPFRINDLY-YINKQIIPALQRVF 1873
+R+ YV+ + G G R ++ DP V P + + + K + L VF
Sbjct: 941 GDRVFYVLTAPVDGRSSGVRNYEIAEDPTYVREHGVPIHADKYFDQVIKSVTNVLSPVF 999
>DPOL_SHV21 (P24907) DNA polymerase (EC 2.7.7.7)
Length = 1009
Score = 179 bits (455), Expect = 5e-44
Identities = 170/684 (24%), Positives = 301/684 (43%), Gaps = 98/684 (14%)
Query: 1219 LSDCKVLNFTDEKHLLKEFTKIVSSSDPDILMGWEIQGSSLGFLAERASHLGFGLLNDLS 1278
+ + +V F E +L F ++ + +I+ G+ I L +L +RA+ + L+D S
Sbjct: 335 VENTEVYEFPSEIDMLHGFFSLIRDFNVEIITGYNISNFDLPYLIDRATQIYNIKLSDYS 394
Query: 1279 RTPSNSWINSQDIKTSEKSILEPDIPDTTSLDCCARESSIIEDEWGRTHASGVHVGGRIV 1338
R + S K + + S + + G I
Sbjct: 395 RVKTGSIFQVHTPKDTGNGFMRS--------------------------VSKIKISGIIA 428
Query: 1339 LNLWRLIRGEVKLNLYSVEAVAEAVLRRKVPSLNHNVLTKWFSRGPGQARYQCIKYIVDR 1398
++++ + + ++ L+ Y ++ VA + K +++ + F GP + R + Y V
Sbjct: 429 IDMYIVCKDKLSLSNYKLDTVANHCIGAKKEDVSYKDIMPLFMSGP-EGRAKIGLYCVID 487
Query: 1399 AKLNLEILNQLDMVNRTSELARVFGIDFFSVLSRGSQYRVESMFLRLAHTQNYVAISPGN 1458
+ L +++L + SE+A++ I VL+ G Q RV S L A +NY+ P +
Sbjct: 488 SVLVMKLLKFFMIHVEISEIAKLAKIPTRRVLTDGQQIRVFSCLLAAARAENYIL--PVS 545
Query: 1459 QQVASQPAMECLPLVMEPESGFYSDPVVVLDFQSLYPSMIIAYNLCFCTCLGKVVPSKTN 1518
V + V+ P GFY++ V+V+DF SLYPS+I A+NLC+ T ++P +
Sbjct: 546 NDVNADGFQGAT--VINPIPGFYNNAVLVVDFASLYPSIIQAHNLCYST----LIPH--H 597
Query: 1519 TLGVSPFVPEQHILQDLKDQILLTPNGVMFVPSKIRRGVLPRLLEEILSTRIMVKQAMKK 1578
L P H+ + +L+ + FV I+ +L RLL LS R ++Q K
Sbjct: 598 ALHNYP-----HLKSSDYETFMLSSGPIHFVKKHIQASLLSRLLTVWLSKRKAIRQ---K 649
Query: 1579 LSPSEQV-LQRIFNARQLALKLISNVTYGYTAAGFSGRMPCAELADSIVQCGRCTLEKAI 1637
L+ E + + I + +QLA+K+ N YG+T SG +PC +A+++ GR LEK+
Sbjct: 650 LAECEDLDTKTILDKQQLAIKVTCNAVYGFTGVA-SGLLPCISIAETVTLQGRTMLEKSK 708
Query: 1638 SFVNL---------------HE-KWNAKVIYGDTDSMFVLLKGRTAKEAFQIGSEIASAI 1681
F+ HE +VIYGDTDS+FV G + + G +A+
Sbjct: 709 IFIEAMTPDTLQEIVPHIVKHEPDAKFRVIYGDTDSLFVECVGYSVDTVVKFGDFLAAFT 768
Query: 1682 T-AMNPSPVTLKMEKVYHPCFLITKKRYVGYSYENPNQIEPVFDAKGIETVRRDTCEAVA 1740
+ + +P+ L+ EK + L+ KKRY+G N + KG++ VR+ C+ V
Sbjct: 769 SEKLFNAPIKLESEKTFQCLLLLAKKRYIGI-LSNDKLL-----MKGVDLVRKTACKFVQ 822
Query: 1741 KIMEQSLRLFFEH------------------------QSLLEVKTYLQRQWKRILSGRVS 1776
+ L L + L+V L K + +G+V
Sbjct: 823 NTSSKILNLILKDPEVKAAAQLLSTKDPDYAFREGLPDGFLKVIDILNESHKNLRTGQVP 882
Query: 1777 LKDFIFAKEVRLGTYSARISSLPPAAIVATKAMRVDRRAEPRYAERIPYVVIHGEPGARL 1836
+++ F+ E+ S + +LP + K + P+ +RIPYV + G+ + +
Sbjct: 883 VEELTFSTELSRPISSYKTENLPHLTVY--KKIITRHEEPPQVHDRIPYVFV-GKTTSCI 939
Query: 1837 VDMVVDPLEVLAIDSPFRINDLYY 1860
+M DP + + P + DLY+
Sbjct: 940 SNMAEDPTYTVQNNIPIAV-DLYF 962
Score = 33.9 bits (76), Expect = 4.7
Identities = 36/179 (20%), Positives = 74/179 (41%), Gaps = 54/179 (30%)
Query: 30 DISHSTFHRGKVNEVP------------VIRVYGSTPAGQKTCLHIHGALPYLYVSCSDI 77
DI +T+ + N++P V+++ G T G C+++ G Y YV +
Sbjct: 94 DIVETTYSEDRCNDIPFKFQTDIIPNGTVLKLLGRTLEGASVCVNVFGQRNYFYVK---V 150
Query: 78 PLQLDQEGDAYTYMVASSLEKALKLKGSADSSRQHVHGCSLVRAKKFYGYCSFEEFFV-- 135
P EG TY++ +L +KF C+++ V
Sbjct: 151 P-----EGGNITYLIKQALN------------------------EKFSPSCAYQTEAVKK 181
Query: 136 KIYLRYYPQD-------VSRAANLL-LAGAVLNKSLQPHESHIPFILQFLVDYNLYGMG 186
KI RY P++ VS + ++ ++ ++++ + E+++ I +F++D + G
Sbjct: 182 KILSRYDPEEHDVFKVTVSSSLSVYKISDSLVSNGCEVFETNVDAIRRFVIDNDFSTFG 240
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.318 0.133 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 234,237,498
Number of Sequences: 164201
Number of extensions: 10010752
Number of successful extensions: 24974
Number of sequences better than 10.0: 111
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 24302
Number of HSP's gapped (non-prelim): 319
length of query: 2018
length of database: 59,974,054
effective HSP length: 125
effective length of query: 1893
effective length of database: 39,448,929
effective search space: 74676822597
effective search space used: 74676822597
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 74 (33.1 bits)
Medicago: description of AC146571.7