BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC142507.1 - phase: 0 
         (542 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

CBK1_YEAST (P53894) Serine/threonine-protein kinase CBK1 (EC 2.7...   400  e-111
CBK1_CANGA (Q6FP74) Serine/threonine-protein kinase CBK1 (EC 2.7...   400  e-111
CBK1_DEBHA (Q6BLJ9) Serine/threonine-protein kinase CBK1 (EC 2.7...   394  e-109
CBK1_PNECA (Q6TGC6) Serine/threonine-protein kinase CBK1 (EC 2.7...   393  e-109
CBK1_YARLI (Q6CFS5) Serine/threonine-protein kinase CBK1 (EC 2.7...   392  e-108
CBK1_ASHGO (Q754N7) Serine/threonine-protein kinase CBK1 (EC 2.7...   392  e-108
CBK1_KLULA (P31034) Serine/threonine-protein kinase CBK1 (EC 2.7...   390  e-108
ORB6_SCHPO (O13310) Serine/threonine-protein kinase orb6 (EC 2.7...   387  e-107
COT1_NEUCR (P38679) Serine/threonine-protein kinase cot-1 (EC 2....   356  1e-97
LTS2_HUMAN (Q9NRM7) Serine/threonine protein kinase LATS2 (EC 2....   346  8e-95
LTS1_HUMAN (O95835) Serine/threonine protein kinase LATS1 (EC 2....   340  7e-93
LTS2_MOUSE (Q7TSJ6) Serine/threonine protein kinase LATS2 (EC 2....   339  9e-93
LTS1_MOUSE (Q8BYR2) Serine/threonine protein kinase LATS1 (EC 2....   337  5e-92
ROC1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.1.37) ...   291  2e-78
ROC1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.1.37...   291  2e-78
ROC1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.1.37...   291  2e-78
ROC1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.1.37...   290  5e-78
DMK_HUMAN (Q09013) Myotonin-protein kinase (EC 2.7.1.-) (Myotoni...   267  5e-71
SID2_SCHPO (Q09898) Serine/threonine-protein kinase sid2 (EC 2.7...   246  8e-65
DBFB_YEAST (P32328) Serine/threonine-protein kinase DBF20 (EC 2....   233  1e-60

>CBK1_YEAST (P53894) Serine/threonine-protein kinase CBK1 (EC
           2.7.1.37) (Cell wall biosynthesis kinase)
          Length = 756

 Score =  400 bits (1027), Expect = e-111
 Identities = 212/471 (45%), Positives = 312/471 (66%), Gaps = 32/471 (6%)

Query: 42  TKLKVEAAKHFVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEMETE 101
           T+ K  A K  +E++Y++  +   ER ERR  LE +L     S+E K   L +  + E++
Sbjct: 279 TQDKAAAVKLKIENFYQSSVKYAIERNERRVELETELTSHNWSEERKSRQLSSLGKKESQ 338

Query: 102 IMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVEYVK 161
            +R +R ++  +DF  + +IGKGAFGEVR+ ++K TG++YAMK L KSEM ++ Q+ +VK
Sbjct: 339 FLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVK 398

Query: 162 SERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFYIGE 221
           +ER++LA  DS  +V LY SFQD +YLYLIME+LPGGD+MT+L+R ++ TE+  +FY+ E
Sbjct: 399 AERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAE 458

Query: 222 TVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLCKPLDCSN--------LQEKDL 273
            +LAIE+IHK  +IHRDIKPDN+L+D  GH+KLSDFGL      ++        LQ+ + 
Sbjct: 459 CILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEA 518

Query: 274 SDGVNRSGVLQSDEL------------TLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDY 321
           ++G+++ G   ++              ++S   S +QQ++ WRK+  R++AYSTVGTPDY
Sbjct: 519 TNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSR-RLMAYSTVGTPDY 577

Query: 322 IAPEVILKRGYGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKD-K 380
           IAPE+ L +GYG ECDWWSLGAIMYE L+G+PPF S+ P+ T RKI +++  L+FP D  
Sbjct: 578 IAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIH 637

Query: 381 LSPEAKDLICRLLCNVKQRLGAK-GADEIKAHPWFKVVEWEKLYQMRAPFIPKVNDELDT 439
           +S EA+DLI RLL +  QRLG   GADEIK+HP+F+ V+W  + Q+ AP+IPK++   DT
Sbjct: 638 ISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSITDT 697

Query: 440 RNFDKFEEEDQKTEPS-PKAGPWRKMLQ--------SKDINFVGYTYKNYE 481
           R F   E E+    P+  +A   R+ +          +D+ F+GYTY  ++
Sbjct: 698 RFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFIGYTYSRFD 748


>CBK1_CANGA (Q6FP74) Serine/threonine-protein kinase CBK1 (EC
           2.7.1.37)
          Length = 773

 Score =  400 bits (1027), Expect = e-111
 Identities = 220/476 (46%), Positives = 309/476 (64%), Gaps = 37/476 (7%)

Query: 39  SNETKLKVEAAKHFVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEM 98
           S  T+ K  A K  VE+YY+   +   ER ERR  LE +L     S+E     L +  + 
Sbjct: 294 SKSTQDKAAAVKLKVENYYQQSVKYAIERNERRVELETELGSHNWSEERNARQLASLGKK 353

Query: 99  ETEIMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVE 158
           E++ +R +R ++  +DF  + +IGKGAFGEVR+ ++K TG++YAMK L KSEM ++ Q+ 
Sbjct: 354 ESQFLRLRRTRLSLEDFHTVQVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLA 413

Query: 159 YVKSERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFY 218
           +VK+ER++LA  DS  IV LY SFQD +YLYLIME+LPGGD+MT+L+R ++ TE+  +FY
Sbjct: 414 HVKAERDVLAGTDSPWIVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFY 473

Query: 219 IGETVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLC----KPLDCSNLQEK--- 271
           + E +LAIE+IHK  +IHRDIKPDN+L+D  GH+KLSDFGL     K  D SN  +K   
Sbjct: 474 MAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHD-SNYYKKLLQ 532

Query: 272 ------------DLSDGVNRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTP 319
                       D  DG N    +  D + L+   S +QQ++ WRK+  R++AYSTVGTP
Sbjct: 533 QDEATTKNGAPNDAGDGSNNRQTMIVDSINLT--MSNRQQIQTWRKSR-RLMAYSTVGTP 589

Query: 320 DYIAPEVILKRGYGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKD 379
           DYIAPE+ L +GYG +CDWWSLGAIMYE L+G+PPF S+ P+ T RKI +++  L+FP+D
Sbjct: 590 DYIAPEIFLYQGYGQDCDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPED 649

Query: 380 -KLSPEAKDLICRLLCNVKQRLGAK-GADEIKAHPWFKVVEWEKLYQMRAPFIPKVNDEL 437
             +S EA+DLI RLL +  QRLG + GADEIK+HP+F+ V+W  + Q+ AP+IPK++   
Sbjct: 650 VHISYEAEDLIRRLLTHSNQRLGRQGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSIT 709

Query: 438 DTRNFDKFEEEDQKTEPS-PKAGPWRKMLQSKDIN-----------FVGYTYKNYE 481
           DTR F   E E+    P+  +A   R+ +    +N           F+GYTY  ++
Sbjct: 710 DTRFFPTDELENVPDSPAMAQAAKQREQMMKNGVNPNQNQVKEDLPFIGYTYSRFD 765


>CBK1_DEBHA (Q6BLJ9) Serine/threonine-protein kinase CBK1 (EC
           2.7.1.37)
          Length = 716

 Score =  394 bits (1013), Expect = e-109
 Identities = 218/467 (46%), Positives = 312/467 (66%), Gaps = 31/467 (6%)

Query: 45  KVEAAKHFVESYYKNQKQNQQERKERRNILENKLADAEV--SKEDKKNLLKNFEEMETEI 102
           K  + K  +E+YY+    +  ER +RR  LE+KL + E   S+E K   L+N  + E++ 
Sbjct: 243 KASSIKLKLENYYQMSVAHAIERNQRRLDLEHKLLNEESGSSEERKNRQLQNLGKKESQF 302

Query: 103 MRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVEYVKS 162
           +R +R K+  +DF  + +IGKGAFGEVR+ +++ TG++YAMK L KSEM ++ Q+ +VK+
Sbjct: 303 LRLRRTKLSLEDFNTVKVIGKGAFGEVRLVQKRDTGKIYAMKTLLKSEMYKKDQLAHVKA 362

Query: 163 ERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFYIGET 222
           ER++LA  DS  +V LY SFQD +YLYLIME+LPGGD+MT+L+R ++ TE+  +FY+ E 
Sbjct: 363 ERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQIFTEDITRFYMAEC 422

Query: 223 VLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLC----KPLDCS---NLQEKDLSD 275
           VLAIE+IHK  +IHRDIKPDN+L+D  GH+KLSDFGL     K  D +    L EK+   
Sbjct: 423 VLAIEAIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLEKENPH 482

Query: 276 GVN-RSGVLQSDEL-----------TLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIA 323
             N ++G LQ+  +            +    S +QQ++ WRK+  R++AYSTVGTPDYIA
Sbjct: 483 HTNPQNGNLQAPSMATNNRNSMMVDAIHLTMSNRQQMQTWRKSR-RLMAYSTVGTPDYIA 541

Query: 324 PEVILKRGYGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKD-KLS 382
           PE+ + +GYG ECDWWSLGAIM+E L+G+PPF S+ P  T RKI +W+  L+ P D  LS
Sbjct: 542 PEIFVHQGYGQECDWWSLGAIMFECLIGWPPFCSETPHETYRKILNWQETLQIPDDIHLS 601

Query: 383 PEAKDLICRLLCNVKQRLGA-KGADEIKAHPWFKVVEWEKLYQMRAPFIPKVNDELDTRN 441
           PE++DLI +LL N + RLG   GADE+K HP+F+ V+W+ + ++ APFIPK+    DTR 
Sbjct: 602 PESEDLIRKLLTNAENRLGRYNGADELKLHPFFRGVDWDTIRKVDAPFIPKLRSITDTRF 661

Query: 442 FDKFEEEDQKTEPS-PKAGPWR-KMLQS-----KDINFVGYTYKNYE 481
           F   E E+    P+  KA   R ++LQ+     +D+ F+GYTY  ++
Sbjct: 662 FPTDELENVPDSPALSKAMEQRDQVLQNGGNVKEDLPFIGYTYSRFD 708


>CBK1_PNECA (Q6TGC6) Serine/threonine-protein kinase CBK1 (EC
           2.7.1.37)
          Length = 507

 Score =  393 bits (1010), Expect = e-109
 Identities = 207/461 (44%), Positives = 300/461 (64%), Gaps = 21/461 (4%)

Query: 42  TKLKVEAAKHFVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEMETE 101
           T  +  + K  +E  YK   +   ER +RR   E KLA    S+E KK  L +  + E++
Sbjct: 53  THERAASVKLKLEHLYKVTVEQTVERNQRRMDFEAKLAQDRGSEERKKRQLNSLGQKESQ 112

Query: 102 IMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVEYVK 161
            +R +R K+  +DF  + +IGKGAFGEVR+ ++  TG++YAMK L KSEM ++ Q+ +VK
Sbjct: 113 FLRLRRTKLSLNDFHTVKVIGKGAFGEVRLVQKIDTGKIYAMKTLLKSEMFKKDQLAHVK 172

Query: 162 SERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFYIGE 221
           +ER++LAE DS  +V LY SFQD +YLYLIME+LPGGD+MT+L++ +  +E+  +FYI E
Sbjct: 173 AERDVLAESDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIKYDTFSEDVTRFYIAE 232

Query: 222 TVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLCKPLDCSN---LQEKDLSDGVN 278
            +LAIE++HK  +IHRDIKPDN+L+D+ GH+KLSDFGL      ++     ++     +N
Sbjct: 233 CILAIEAVHKLGFIHRDIKPDNILIDKTGHIKLSDFGLSMGFHKTHDNAYYQRLFESKIN 292

Query: 279 RSGVLQSDEL---TLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVILKRGYGVE 335
            S     + L   T+S   S + ++  W+KN  R++AYSTVGTPDYIAPE+  + GYG E
Sbjct: 293 TSTSSTQNSLMVDTISLTMSSKDKIATWKKNR-RIMAYSTVGTPDYIAPEIFTQHGYGQE 351

Query: 336 CDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKD-KLSPEAKDLICRLLC 394
           CDWWSLGAIM+E L+G+PPF S++   T RKI +W+  L FP+D  LS EA+DLI +LL 
Sbjct: 352 CDWWSLGAIMFECLIGWPPFCSENAHETYRKIINWRENLYFPEDLHLSAEAEDLIRKLLT 411

Query: 395 NVKQRLGAKGADEIKAHPWFKVVEWEKLYQMRAPFIPKVNDELDTRNFDKFEEEDQKTEP 454
           +  QRLG  GA++IK HP+F+ V W+ + ++ APFIP++    DT  F++ +     T  
Sbjct: 412 SADQRLGRYGANDIKLHPFFRGVNWDTIREINAPFIPQLKSITDTSYFEEIDTIPNITMN 471

Query: 455 SPKAGPWRKMLQSK-------DINFVGYTYKNYEMVDANAI 488
           SP       +LQ+K       ++ FVGYTYK ++M+    I
Sbjct: 472 SP------PVLQNKIPSDVDQNLAFVGYTYKRFDMMTQKGI 506


>CBK1_YARLI (Q6CFS5) Serine/threonine-protein kinase CBK1 (EC
           2.7.1.37)
          Length = 588

 Score =  392 bits (1006), Expect = e-108
 Identities = 211/449 (46%), Positives = 295/449 (64%), Gaps = 19/449 (4%)

Query: 53  VESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEMETEIMRRQRLKMGA 112
           + +YYK   Q+  ER +RR+  E  +  A  S+E +  +L N+ + ET  +R +R +M  
Sbjct: 146 ISTYYKGIVQHAIERHQRRSAAEASVEQA-TSEERRNRVLTNYGKKETAYLRMRRTRMAL 204

Query: 113 DDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVEYVKSERNLLAEVDS 172
           +DF  + +IGKGAFGEVR+ +++  G++YAMK + K EM  + Q  +VK+ER++LA+ DS
Sbjct: 205 EDFVTVKVIGKGAFGEVRLVQKRDNGKIYAMKTMLKKEMDMKEQWAHVKAERDVLADSDS 264

Query: 173 NCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFYIGETVLAIESIHKH 232
             IV LY SFQDD YLYLIME+LPGGD+MT+L++ +V +E+  +FYI E VLAIE+IHK 
Sbjct: 265 PWIVSLYFSFQDDLYLYLIMEFLPGGDLMTMLIKYDVFSEDITRFYIAECVLAIEAIHKL 324

Query: 233 NYIHRDIKPDNLLLDRNGHVKLSDFGLCKPL--DCSNLQEKDLSDGVNRSGVLQSDELTL 290
            +IHRDIKPDN+L+D+ GH+KLSDFGL        S+   K L DG + +   Q      
Sbjct: 325 GFIHRDIKPDNILIDKTGHIKLSDFGLSTGFHKTHSSAYWKKLKDGTSSNPATQMGPPQN 384

Query: 291 SPNQS--------QQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVILKRGYGVECDWWSLG 342
           +  QS         +QQ+  WRKN  R++AYSTVGTPDYIAPE+ + +GYG ECDWWSLG
Sbjct: 385 TNRQSTYDSIHLTMRQQISTWRKNR-RLMAYSTVGTPDYIAPEIFVHQGYGQECDWWSLG 443

Query: 343 AIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKD-KLSPEAKDLICRLLCNVKQRLG 401
           AIM+E LVG+PPF S+ PR T  KI +W+  L+FP D  LSPE++DLI RLL + + RLG
Sbjct: 444 AIMFECLVGWPPFCSEQPRETYHKIINWRETLQFPDDVHLSPESEDLIRRLLTSSENRLG 503

Query: 402 -AKGADEIKAHPWFKVVEWEKLYQMRAPFIPKVNDELDTRNFDKFEEEDQKTEPSPKAGP 460
              GA+EIK+HP+F+ V+W  + +  APF+PK++   DT  F   E  D    P   +  
Sbjct: 504 RIGGANEIKSHPFFRGVDWSSIREFNAPFVPKLSSITDTSYFPTDELGDVSEYPQQSS-- 561

Query: 461 WRKMLQSKDINFVGYTYKNYE-MVDANAI 488
             +  +S D+ F+GYT+  ++ M   NAI
Sbjct: 562 --RSDRSSDLPFIGYTFSRFDNMTRRNAI 588


>CBK1_ASHGO (Q754N7) Serine/threonine-protein kinase CBK1 (EC
           2.7.1.37)
          Length = 719

 Score =  392 bits (1006), Expect = e-108
 Identities = 219/483 (45%), Positives = 313/483 (64%), Gaps = 45/483 (9%)

Query: 39  SNETKLKVEAAKHFVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEM 98
           S  T+ K  A K  VE++Y++   +  ER +RR  LE++L     S+E K   L +  + 
Sbjct: 234 SKSTQEKAAAVKLKVENFYQSSVNHAIERNQRRVELESQLLSHGWSEERKNRQLSSLGKK 293

Query: 99  ETEIMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVE 158
           E++ +R +R ++  +DF  + +IGKGAFGEVR+ ++K TG++YAMK L KSEM ++ Q+ 
Sbjct: 294 ESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLA 353

Query: 159 YVKSERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFY 218
           +VK+ER++LA  DS  +V LY SFQD +YLYLIME+LPGGD+MT+L+R ++ TE+  +FY
Sbjct: 354 HVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFY 413

Query: 219 IGETVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLC----KPLDCSNLQEKDLS 274
           + E +LAIE+IHK  +IHRDIKPDN+L+D  GH+KLSDFGL     K  D SN  +K L 
Sbjct: 414 MAECILAIEAIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHD-SNYYKKLLQ 472

Query: 275 D----------------------GVNRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLA 312
           +                      G NR+ +L  D + L+   + +QQ++ WRK+  R++A
Sbjct: 473 EDEQQQNGGNMGKYPASGGGGNGGGNRNTML-VDAIHLT--MTNRQQMQTWRKSR-RLMA 528

Query: 313 YSTVGTPDYIAPEVILKRGYGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKT 372
           YSTVGTPDYIAPE+ L +GYG ECDWWSLGAIMYE L+G+PPF S+ P+ T RKI +++ 
Sbjct: 529 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 588

Query: 373 YLKFPKD-KLSPEAKDLICRLLCNVKQRLGAKGADEIKAHPWFKVVEWEKLYQMRAPFIP 431
            L FP D  +S EA+DLI RLL +  +RLG  GA+EIK HP+F+ V+WE + Q+ AP+IP
Sbjct: 589 TLVFPDDIHISYEAEDLIRRLLSHADERLGRHGANEIKNHPFFRGVDWETIRQVGAPYIP 648

Query: 432 KVNDELDTRNFDKFEEED------------QKTEPSPKAGPWRKMLQSK-DINFVGYTYK 478
           K++   DTR F   E E+            Q+ +   + G      Q+K D+ F+GYTY 
Sbjct: 649 KLSSVTDTRFFPTDELENVPDSPAMAQAAKQREQMLKQGGSAANTAQAKEDLPFIGYTYS 708

Query: 479 NYE 481
            ++
Sbjct: 709 RFD 711


>CBK1_KLULA (P31034) Serine/threonine-protein kinase CBK1 (EC
           2.7.1.37)
          Length = 718

 Score =  390 bits (1002), Expect = e-108
 Identities = 217/484 (44%), Positives = 309/484 (63%), Gaps = 47/484 (9%)

Query: 42  TKLKVEAAKHFVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEMETE 101
           T+ K  A K  +E++Y++      ER +RR  LE++LA  + S+E K   L +  + E++
Sbjct: 230 TQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASLGKKESQ 289

Query: 102 IMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVEYVK 161
            +R +R ++  DDF  + +IGKGAFGEVR+ ++K TG++YAMK L KSEM  + Q+ +VK
Sbjct: 290 FLRLRRTRLSLDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVK 349

Query: 162 SERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFYIGE 221
           +ER++LA  DS  +V LY SFQD +YLYLIME+LPGGD+MT+L+R ++ TE+  +FY+ E
Sbjct: 350 AERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAE 409

Query: 222 TVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLC----KPLDCS----------- 266
            +LAIE IHK  +IHRDIKPDN+L+D  GH+KLSDFGL     K  D S           
Sbjct: 410 CILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYKKLLQEDEA 469

Query: 267 -------------NLQEKDLSDGVNRSG--VLQSDELTLSPNQSQQQQLEHWRKNHSRML 311
                        NLQ+  L +  N      +  D + L+   + +QQ++ WRK+  R++
Sbjct: 470 KKQQQQQQQQQQLNLQKPQLPNETNNGNRNTMLVDAIHLT--MTNRQQMQTWRKSR-RLM 526

Query: 312 AYSTVGTPDYIAPEVILKRGYGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWK 371
           AYSTVGTPDYIAPE+ L +GYG ECDWWSLGAIMYE L+G+PPF S+ P+ T RKI +++
Sbjct: 527 AYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 586

Query: 372 TYLKFPKD-KLSPEAKDLICRLLCNVKQRLGAK-GADEIKAHPWFKVVEWEKLYQMRAPF 429
             L+FP D  +S EA+DLI RLL + + RLG   GADEIKAHP+F  V+W  + Q+ AP+
Sbjct: 587 QTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPY 646

Query: 430 IPKVNDELDTRNFDKFEEEDQKTEPS-PKAGPWRKMLQS-----------KDINFVGYTY 477
           IPK++   DTR F   E E+    P+  +A   R+ + +           +D+ F+GYTY
Sbjct: 647 IPKLSSVTDTRFFPTDELENVPDSPAMAQAARQREQMMTQQQGVPQSNAKEDLPFIGYTY 706

Query: 478 KNYE 481
             ++
Sbjct: 707 SRFD 710


>ORB6_SCHPO (O13310) Serine/threonine-protein kinase orb6 (EC
           2.7.1.37)
          Length = 469

 Score =  387 bits (994), Expect = e-107
 Identities = 199/443 (44%), Positives = 291/443 (64%), Gaps = 12/443 (2%)

Query: 45  KVEAAKHFVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEMETEIMR 104
           KV+  K ++E YYK    +  ER +RR  LE +LA    S+E K   L+   E E++ +R
Sbjct: 23  KVQKTKKYIEHYYKVAVDHAVERNQRRINLEQRLATERGSEERKNRQLRASGEKESQFLR 82

Query: 105 RQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVEYVKSER 164
            +R ++  +DF  + +IGKGAFGEVR+ ++  TG++YAMK L K+EM +R Q+ +VK+ER
Sbjct: 83  FRRTRLSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAER 142

Query: 165 NLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFYIGETVL 224
           +LL E DS  +V LY +FQD  YLYLIME+LPGGD+MT+L+  +  +E+  +FY+ E VL
Sbjct: 143 DLLVESDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVL 202

Query: 225 AIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLC----KPLDCSNLQEKDLSDGVNRS 280
           AI  +H+  YIHRDIKPDN+L+DR+GH+KLSDFGL     K    ++  +    + V R 
Sbjct: 203 AIADVHRMGYIHRDIKPDNILIDRDGHIKLSDFGLSTGFYKQDQSASYMKPRTGNTVKRG 262

Query: 281 GVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVILKRGYGVECDWWS 340
            ++ +  LT+    S + ++  W+KN  R++AYSTVGTPDYIAPE+ L++GYG +CDWWS
Sbjct: 263 QMVDAIWLTM----SSKDKMATWKKNR-RVMAYSTVGTPDYIAPEIFLQQGYGQDCDWWS 317

Query: 341 LGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKD-KLSPEAKDLICRLLCNVKQR 399
           LGAIM+E L+G+PPF S++   T RKI +W+  L FP D  LS EA+DL+ RL+ + + R
Sbjct: 318 LGAIMFECLIGWPPFCSENSHETYRKIINWRETLTFPNDIHLSIEARDLMDRLMTDSEHR 377

Query: 400 LGAKGADEIKAHPWFKVVEWEKLYQMRAPFIPKVNDELDTRNF--DKFEEEDQKTEPSPK 457
           LG  GA EI  HP+F  ++W+ + +  APFIP +    DT  F  D+ E+  ++      
Sbjct: 378 LGRGGAIEIMQHPFFTGIDWDHIRETAAPFIPNLKSITDTHYFPVDELEQVPEQPVTQQP 437

Query: 458 AGPWRKMLQSKDINFVGYTYKNY 480
           A    + L+  ++ F+GYTYK +
Sbjct: 438 ASVDPQTLEQTNLAFLGYTYKKF 460


>COT1_NEUCR (P38679) Serine/threonine-protein kinase cot-1 (EC
           2.7.1.37) (Colonial temperature-sensitive 1)
          Length = 598

 Score =  356 bits (913), Expect = 1e-97
 Identities = 191/463 (41%), Positives = 299/463 (64%), Gaps = 26/463 (5%)

Query: 37  PPSNETKLKVEAAKHFVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFE 96
           P +N  + K          ++K+  +  +ER +R++ +E KL +   ++  ++++     
Sbjct: 140 PNANNNQKK---CSQLASDFFKDSVKRARERNQRQSEMEQKLGETNDARR-RESIWSTAG 195

Query: 97  EMETEIMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQ 156
             E + +R  R K   ++++ + +IGKGAFGEV++ ++K  G+VYAMK L K+EM ++ Q
Sbjct: 196 RKEGQYLRFLRTKDKPENYQTIKIIGKGAFGEVKLVQKKADGKVYAMKSLIKTEMFKKDQ 255

Query: 157 VEYVKSERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAK 216
           + +V++ER++LAE DS  +VKLY +FQD  +LY++ME+LPGGD+MT+L++ E+ +E+  +
Sbjct: 256 LAHVRAERDILAESDSPWVVKLYTTFQDANFLYMLMEFLPGGDLMTMLIKYEIFSEDITR 315

Query: 217 FYIGETVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLC---KPLDCSN-----L 268
           FYI E VLAI+++HK  +IHRDIKPDN+LLDR GHVKL+DFGL      L  +N     L
Sbjct: 316 FYIAEIVLAIDAVHKLGFIHRDIKPDNILLDRGGHVKLTDFGLSTGFHKLHDNNYYTQLL 375

Query: 269 QEKDLSDGVNRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVIL 328
           Q K      NR+ V   D++ L+   S + Q+  WR++  R++AYSTVGTPDYIAPE+  
Sbjct: 376 QGKSNKPRDNRNSV-AIDQINLT--VSNRAQINDWRRSR-RLMAYSTVGTPDYIAPEIFT 431

Query: 329 KRGYGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKD-KLSPEAKD 387
             GY  +CDWWSLG IM+E LVG+PPF ++D   T RKI +W+  L FP D  L  +A++
Sbjct: 432 GHGYSFDCDWWSLGTIMFECLVGWPPFCAEDSHDTYRKIVNWRHSLYFPDDITLGVDAEN 491

Query: 388 LICRLLCNVKQRLGAKGADEIKAHPWFKVVEWEKLYQMRAPFIPKVNDELDTRNF--DKF 445
           LI  L+CN + RLG  GA EIK+H +F+ VE++ L ++RAPF P++   +DT  F  D+ 
Sbjct: 492 LIRSLICNTENRLGRGGAHEIKSHAFFRGVEFDSLRRIRAPFEPRLTSAIDTTYFPTDEI 551

Query: 446 EEEDQKT-----EPSPKAGPWRKMLQSKDIN--FVGYTYKNYE 481
           ++ D  T     + +  A    +  +S +++  F+GYT+K ++
Sbjct: 552 DQTDNATLLKAQQAARGAAAPAQQEESPELSLPFIGYTFKRFD 594


>LTS2_HUMAN (Q9NRM7) Serine/threonine protein kinase LATS2 (EC
            2.7.1.37) (Large tumor suppressor homolog 2)
            (Serine/threonine kinase kpm) (Kinase phosphorylated
            during mitosis protein) (Warts-like kinase)
          Length = 1088

 Score =  346 bits (888), Expect = 8e-95
 Identities = 189/452 (41%), Positives = 274/452 (59%), Gaps = 10/452 (2%)

Query: 48   AAKHFVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEMETEIMRRQR 107
            A K F+E + +N  +  Q++  RR  LE ++A A + + +++ + K   + E+   R +R
Sbjct: 601  AFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKR 660

Query: 108  LKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVEYVKSERNLL 167
             KM    F  +  +G GAFGEV +  +  T  +YAMK L+K ++L R QV +VK+ER++L
Sbjct: 661  AKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVKAERDIL 720

Query: 168  AEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFYIGETVLAIE 227
            AE D+  +VKLY SFQD + LY +M+Y+PGGDMM+LL+R EV  E+ A+FYI E  LAIE
Sbjct: 721  AEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIE 780

Query: 228  SIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLCKPLDCS-NLQEKDLSDGVNRSGVLQSD 286
            S+HK  +IHRDIKPDN+L+D +GH+KL+DFGLC     + N +       V +  +  SD
Sbjct: 781  SVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSD 840

Query: 287  ELTLSPNQSQQQQL----EHWRKNHSRMLAYSTVGTPDYIAPEVILKRGYGVECDWWSLG 342
                  N     +L    +  RK H R LA+S VGTP+YIAPEV+L++GY   CDWWS+G
Sbjct: 841  LWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVG 900

Query: 343  AIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKD-KLSPEAKDLICRLLCNVKQRLG 401
             I++EMLVG PPF +  P  T  K+ +W+  L  P   KLSPEA+DLI +L C+   RLG
Sbjct: 901  VILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSADHRLG 960

Query: 402  AKGADEIKAHPWFKVVEWEK-LYQMRAPFIPKVNDELDTRNFDKFEEE---DQKTEPSPK 457
              GAD++KAHP+F  +++   + +  AP++P ++  +DT NFD  +EE   +  +E S K
Sbjct: 961  RNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPMDTSNFDPVDEESPWNDASEGSTK 1020

Query: 458  AGPWRKMLQSKDINFVGYTYKNYEMVDANAIP 489
            A        +K      Y +      D N  P
Sbjct: 1021 AWDTLTSPNNKHPEHAFYEFTFRRFFDDNGYP 1052


>LTS1_HUMAN (O95835) Serine/threonine protein kinase LATS1 (EC
            2.7.1.37) (Large tumor suppressor homolog 1) (WARTS
            protein kinase) (h-warts)
          Length = 1130

 Score =  340 bits (871), Expect = 7e-93
 Identities = 185/460 (40%), Positives = 274/460 (59%), Gaps = 23/460 (5%)

Query: 47   EAAKHFVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEMETEIMRRQ 106
            +A K F+E + +N  ++ Q+R  R+  LEN++    +S++ +  + K   + E+  +R +
Sbjct: 637  QAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLK 696

Query: 107  RLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVEYVKSERNL 166
            R KM    F  +  +G GAFGEV + R+  T  +YA K L+K ++L R QV +VK+ER++
Sbjct: 697  RAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDI 756

Query: 167  LAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFYIGETVLAI 226
            LAE D+  +V+LY SFQD + LY +M+Y+PGGDMM+LL+R  +  E+ A+FYI E   A+
Sbjct: 757  LAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAV 816

Query: 227  ESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLC---------KPLDCSNLQEKDLSDGV 277
            ES+HK  +IHRDIKPDN+L+DR+GH+KL+DFGLC         K     +   +D  D  
Sbjct: 817  ESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFS 876

Query: 278  NRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVILKRGYGVECD 337
            N  G    D  +       +       + H R LA+S VGTP+YIAPEV+L+ GY   CD
Sbjct: 877  NEWG----DPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCD 932

Query: 338  WWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKF-PKDKLSPEAKDLICRLLCNV 396
            WWS+G I++EMLVG PPF +  P  T  K+ +W+T L   P+ KLSPEA DLI +L    
Sbjct: 933  WWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGP 992

Query: 397  KQRLGAKGADEIKAHPWFKVVEWEK-LYQMRAPFIPKVNDELDTRNFDK------FEEED 449
            + RLG  GADEIKAHP+FK +++   L Q  A +IPK+    DT NFD       + +++
Sbjct: 993  EDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDDN 1052

Query: 450  QKTEPSPKAGPWRKMLQSKDINFVGYTYKNYEMVDANAIP 489
            ++   +     W K  +  +  F  +T++ +   D N  P
Sbjct: 1053 EEENVNDTLNGWYKNGKHPEHAFYEFTFRRF--FDDNGYP 1090


>LTS2_MOUSE (Q7TSJ6) Serine/threonine protein kinase LATS2 (EC
            2.7.1.37) (Large tumor suppressor homolog 2)
            (Serine/threonine kinase kpm) (Kinase phosphorylated
            during mitosis protein)
          Length = 1042

 Score =  339 bits (870), Expect = 9e-93
 Identities = 189/462 (40%), Positives = 275/462 (58%), Gaps = 30/462 (6%)

Query: 48   AAKHFVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEMETEIMRRQR 107
            A K F+E + +N  +  Q++  RR  LE ++A A + + +++ + K   + E+   R +R
Sbjct: 559  AFKFFMEQHVENVIKTYQQKVSRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKR 618

Query: 108  LKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVEYVKSERNLL 167
             KM    F  +  +G GAFGEV +  +  T  +YAMK L+K ++L R QV +VK+ER++L
Sbjct: 619  AKMDKSMFVKIKTLGIGAFGEVCLACKLDTHALYAMKTLRKKDVLNRNQVAHVKAERDIL 678

Query: 168  AEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFYIGETVLAIE 227
            AE D+  +VKLY SFQD + LY +M+Y+PGGDMM+LL+R EV  E+ A+FYI E  LAIE
Sbjct: 679  AEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIE 738

Query: 228  SIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLC---------------KPLDCSNLQEKD 272
            S+HK  +IHRDIKPDN+L+D +GH+KL+DFGLC                 +   +++  D
Sbjct: 739  SVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGNHMRQDSMEPGD 798

Query: 273  LSDGVNRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVILKRGY 332
            L D V  S     D L     ++Q+Q        H R LA+S VGTP+YIAPEV+L++GY
Sbjct: 799  LWDDV--SNCRCGDRLKTLEQRAQKQ--------HQRCLAHSLVGTPNYIAPEVLLRKGY 848

Query: 333  GVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKD-KLSPEAKDLICR 391
               CDWWS+G I++EMLVG PPF +  P  T  K+ +W++ L  P   +LS EA+DLI +
Sbjct: 849  TQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWESTLHIPTQVRLSAEARDLITK 908

Query: 392  LLCNVKQRLGAKGADEIKAHPWFKVVEWEK-LYQMRAPFIPKVNDELDTRNFDKFEEEDQ 450
            L C    RLG  GAD++KAHP+F  +++ + + +  AP++P ++  +DT NFD  +EE  
Sbjct: 909  LCCAADCRLGRDGADDLKAHPFFNTIDFSRDIRKQPAPYVPTISHPMDTSNFDPVDEESP 968

Query: 451  KTEPS-PKAGPWRKML--QSKDINFVGYTYKNYEMVDANAIP 489
              E S   A  W  +    SK      Y +      D N  P
Sbjct: 969  WHEASGESAKAWDTLASPSSKHPEHAFYEFTFRRFFDDNGYP 1010


>LTS1_MOUSE (Q8BYR2) Serine/threonine protein kinase LATS1 (EC
            2.7.1.37) (Large tumor suppressor homolog 1) (WARTS
            protein kinase)
          Length = 1129

 Score =  337 bits (864), Expect = 5e-92
 Identities = 187/460 (40%), Positives = 269/460 (57%), Gaps = 23/460 (5%)

Query: 47   EAAKHFVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEMETEIMRRQ 106
            +A K F+E + +N  ++ Q+R  R+  LEN++    +S++ +  + K   + E+  +R +
Sbjct: 636  QAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLK 695

Query: 107  RLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVEYVKSERNL 166
            R KM    F  +  +G GAFGEV + R+  T  +YA K L+K ++L R QV +VK+ER++
Sbjct: 696  RAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDI 755

Query: 167  LAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFYIGETVLAI 226
            LAE D+  +V+LY SFQD + LY +M+Y+PGGDMM+LL+R  +  EN A+FYI E   A+
Sbjct: 756  LAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAV 815

Query: 227  ESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLC---------KPLDCSNLQEKDLSDGV 277
            ES+HK  +IHRDIKPDN+L+DR+GH+KL+DFGLC         K     +   +D  D  
Sbjct: 816  ESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFS 875

Query: 278  NRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVILKRGYGVECD 337
            N  G    D          +       + H R LA+S VGTP+YIAPEV+L+ GY   CD
Sbjct: 876  NEWG----DPSNCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCD 931

Query: 338  WWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKF-PKDKLSPEAKDLICRLLCNV 396
            WWS+G I+ EMLVG PPF +  P  T  K+  W+T L   P+ KLSPEA DLI +L    
Sbjct: 932  WWSVGVILCEMLVGQPPFLAQTPLETQMKVIIWQTSLHIPPQAKLSPEASDLIIKLCRGP 991

Query: 397  KQRLGAKGADEIKAHPWFKVVEWEK-LYQMRAPFIPKVNDELDTRNFDKFEEE------D 449
            + RLG  GADEIKAHP+FK +++   L Q  A +IPK+    DT NFD  + +       
Sbjct: 992  EDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDGS 1051

Query: 450  QKTEPSPKAGPWRKMLQSKDINFVGYTYKNYEMVDANAIP 489
            ++   S     W K  +  +  F  +T++ +   D N  P
Sbjct: 1052 EEENISDTLSGWYKNGKHPEHAFYEFTFRRF--FDDNGYP 1089


>ROC1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.1.37)
           (Rho-associated, coiled-coil containing protein kinase
           1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase
           ROK beta)
          Length = 1369

 Score =  291 bits (746), Expect = 2e-78
 Identities = 162/398 (40%), Positives = 236/398 (58%), Gaps = 57/398 (14%)

Query: 89  KNLLKNFEEMETEIMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQK 148
           KN+       +  I + + L+M A+D+E + +IG+GAFGEV++ R K+T +VYAMK L K
Sbjct: 50  KNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSK 109

Query: 149 SEMLRRGQVEYVKSERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRRE 208
            EM++R    +   ER+++A  +S  +V+L+ +FQDD YLY++MEY+PGGD++ L+   +
Sbjct: 110 FEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD 169

Query: 209 VLTENEAKFYIGETVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLCKPLDCSNL 268
           V  E  A+FY  E VLA+++IH   +IHRD+KPDN+LLD++GH+KL+DFG C  +     
Sbjct: 170 V-PEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKM----- 223

Query: 269 QEKDLSDGVNRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVIL 328
                    N+ G+++ D                           + VGTPDYI+PEV+ 
Sbjct: 224 ---------NKEGMVRCD---------------------------TAVGTPDYISPEVLK 247

Query: 329 KRG----YGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKDK-LSP 383
            +G    YG ECDWWS+G  +YEMLVG  PF++D    T  KI + K  L FP D  +S 
Sbjct: 248 SQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISK 307

Query: 384 EAKDLICRLLCNVKQRLGAKGADEIKAHPWFKVVE--WEKLYQMRAPFIPKVNDELDTRN 441
           EAK+LIC  L + + RLG  G +EIK H +FK  +  WE L    AP +P ++ ++DT N
Sbjct: 308 EAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSN 367

Query: 442 FDKFEEE--DQKTEPSPKAGPWRKMLQSKDINFVGYTY 477
           FD  EE+  D++T P PKA           + FVG+TY
Sbjct: 368 FDDLEEDKGDEETFPIPKA------FVGNQLPFVGFTY 399


>ROC1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.1.37)
           (Rho-associated, coiled-coil containing protein kinase
           1) (p160 ROCK-1) (p160ROCK) (cAMP dependent protein
           kinase ROCK-I) (CePKA) (Corneal epithelial
           Rho-associated-Ser/Thr kinase 1) (HEBM
          Length = 1354

 Score =  291 bits (746), Expect = 2e-78
 Identities = 162/398 (40%), Positives = 236/398 (58%), Gaps = 57/398 (14%)

Query: 89  KNLLKNFEEMETEIMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQK 148
           KN+       +  I + + L+M A+D+E + +IG+GAFGEV++ R K+T +VYAMK L K
Sbjct: 50  KNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSK 109

Query: 149 SEMLRRGQVEYVKSERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRRE 208
            EM++R    +   ER+++A  +S  +V+L+ +FQDD YLY++MEY+PGGD++ L+   +
Sbjct: 110 FEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD 169

Query: 209 VLTENEAKFYIGETVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLCKPLDCSNL 268
           V  E  A+FY  E VLA+++IH   +IHRD+KPDN+LLD++GH+KL+DFG C  +     
Sbjct: 170 V-PEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKM----- 223

Query: 269 QEKDLSDGVNRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVIL 328
                    N+ G+++ D                           + VGTPDYI+PEV+ 
Sbjct: 224 ---------NKEGMVRCD---------------------------TAVGTPDYISPEVLK 247

Query: 329 KRG----YGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKDK-LSP 383
            +G    YG ECDWWS+G  +YEMLVG  PF++D    T  KI + K  L FP D  +S 
Sbjct: 248 SQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISK 307

Query: 384 EAKDLICRLLCNVKQRLGAKGADEIKAHPWFKVVE--WEKLYQMRAPFIPKVNDELDTRN 441
           EAK+LIC  L + + RLG  G +EIK H +FK  +  WE L    AP +P ++ ++DT N
Sbjct: 308 EAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSN 367

Query: 442 FDKFEEE--DQKTEPSPKAGPWRKMLQSKDINFVGYTY 477
           FD  EE+  D++T P PKA           + FVG+TY
Sbjct: 368 FDDLEEDKGDEETFPIPKA------FVGNQLPFVGFTY 399


>ROC1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.1.37)
           (Rho-associated, coiled-coil containing protein kinase
           1) (p160 ROCK-1) (p160ROCK)
          Length = 1354

 Score =  291 bits (746), Expect = 2e-78
 Identities = 162/398 (40%), Positives = 236/398 (58%), Gaps = 57/398 (14%)

Query: 89  KNLLKNFEEMETEIMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQK 148
           KN+       +  I + + L+M A+D+E + +IG+GAFGEV++ R K+T +VYAMK L K
Sbjct: 50  KNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSK 109

Query: 149 SEMLRRGQVEYVKSERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRRE 208
            EM++R    +   ER+++A  +S  +V+L+ +FQDD YLY++MEY+PGGD++ L+   +
Sbjct: 110 FEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD 169

Query: 209 VLTENEAKFYIGETVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLCKPLDCSNL 268
           V  E  A+FY  E VLA+++IH   +IHRD+KPDN+LLD++GH+KL+DFG C  +     
Sbjct: 170 V-PEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKM----- 223

Query: 269 QEKDLSDGVNRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVIL 328
                    N+ G+++ D                           + VGTPDYI+PEV+ 
Sbjct: 224 ---------NKEGMVRCD---------------------------TAVGTPDYISPEVLK 247

Query: 329 KRG----YGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKDK-LSP 383
            +G    YG ECDWWS+G  +YEMLVG  PF++D    T  KI + K  L FP D  +S 
Sbjct: 248 SQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISK 307

Query: 384 EAKDLICRLLCNVKQRLGAKGADEIKAHPWFKVVE--WEKLYQMRAPFIPKVNDELDTRN 441
           EAK+LIC  L + + RLG  G +EIK H +FK  +  WE L    AP +P ++ ++DT N
Sbjct: 308 EAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSN 367

Query: 442 FDKFEEE--DQKTEPSPKAGPWRKMLQSKDINFVGYTY 477
           FD  EE+  D++T P PKA           + FVG+TY
Sbjct: 368 FDDLEEDKGDEETFPIPKA------FVGNQLPFVGFTY 399


>ROC1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.1.37)
           (Rho-associated, coiled-coil containing protein kinase
           1) (p160 ROCK-1) (p160ROCK)
          Length = 1354

 Score =  290 bits (743), Expect = 5e-78
 Identities = 163/410 (39%), Positives = 241/410 (58%), Gaps = 57/410 (13%)

Query: 89  KNLLKNFEEMETEIMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQK 148
           KN+       +  I + + L+M A+D+E + +IG+GAFGEV++ R K+T +VYAMK L K
Sbjct: 50  KNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSK 109

Query: 149 SEMLRRGQVEYVKSERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRRE 208
            EM++R    +   ER+++A  +S  +V+L+ +FQDD YLY++MEY+PGGD++ L+   +
Sbjct: 110 FEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD 169

Query: 209 VLTENEAKFYIGETVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLCKPLDCSNL 268
           V  E  A+FY  E VLA+++IH   +IHRD+KPDN+LLD++GH+KL+DFG C  +     
Sbjct: 170 V-PEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKM----- 223

Query: 269 QEKDLSDGVNRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVIL 328
                    N+ G+++ D                           + VGTPDYI+PEV+ 
Sbjct: 224 ---------NKEGMVRCD---------------------------TAVGTPDYISPEVLK 247

Query: 329 KRG----YGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKDK-LSP 383
            +G    YG ECDWWS+G  +YEMLVG  PF++D    T  KI + K  L FP D  +S 
Sbjct: 248 SQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISK 307

Query: 384 EAKDLICRLLCNVKQRLGAKGADEIKAHPWFKVVE--WEKLYQMRAPFIPKVNDELDTRN 441
           EAK+LIC  L + + RLG  G +EIK H +FK  +  WE L    AP +P ++ ++DT N
Sbjct: 308 EAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSN 367

Query: 442 FDKFEEE--DQKTEPSPKAGPWRKMLQSKDINFVGYTYKNYEMVDANAIP 489
           FD  EE+  +++T P PKA           + FVG+TY +     ++A P
Sbjct: 368 FDDLEEDKGEEETFPIPKA------FVGNQLPFVGFTYYSNRRYLSSANP 411


>DMK_HUMAN (Q09013) Myotonin-protein kinase (EC 2.7.1.-) (Myotonic
           dystrophy protein kinase) (MDPK) (DM-kinase) (DMK)
           (DMPK) (MT-PK)
          Length = 639

 Score =  267 bits (683), Expect = 5e-71
 Identities = 157/407 (38%), Positives = 221/407 (53%), Gaps = 59/407 (14%)

Query: 99  ETEIMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVE 158
           E  ++R + +++  DDFE L +IG+GAF EV + + K TGQVYAMK + K +ML+RG+V 
Sbjct: 65  EPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVS 124

Query: 159 YVKSERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMR-REVLTENEAKF 217
             + ER++L   D   I +L+ +FQD+ YLYL+MEY  GGD++TLL +  E +    A+F
Sbjct: 125 CFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARF 184

Query: 218 YIGETVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLCKPLDCSNLQEKDLSDGV 277
           Y+ E V+AI+S+H+  Y+HRDIKPDN+LLDR GH++L+DFG C  L          +DG 
Sbjct: 185 YLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKL---------RADGT 235

Query: 278 NRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVILKRG------ 331
            RS V                                 VGTPDY++PE++   G      
Sbjct: 236 VRSLV--------------------------------AVGTPDYLSPEILQAVGGGPGTG 263

Query: 332 -YGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFP--KDKLSPEAKDL 388
            YG ECDWW+LG   YEM  G  PF++D    T  KI H+K +L  P   + +  EA+D 
Sbjct: 264 SYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDF 323

Query: 389 ICRLLCNVKQRLGAKGADEIKAHPWFKVVEWEKLYQMRAPFIPKVNDELDTRNFDKFEEE 448
           I RLLC  + RLG  GA + + HP+F  ++W+ L     PF P      DT NFD    E
Sbjct: 324 IQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFDLV--E 381

Query: 449 DQKTEPSPKAGPWRKMLQ-----SKDINFVGYTYKNYEMVDANAIPG 490
           D  T      G     ++        + FVGY+Y    + D+  +PG
Sbjct: 382 DGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMALRDSE-VPG 427


>SID2_SCHPO (Q09898) Serine/threonine-protein kinase sid2 (EC
           2.7.1.37)
          Length = 607

 Score =  246 bits (629), Expect = 8e-65
 Identities = 140/446 (31%), Positives = 241/446 (53%), Gaps = 29/446 (6%)

Query: 52  FVESYYKNQKQNQQERKERRNILENKLADAEVSKEDKKNLLKNFEEMETEIMRRQRLKMG 111
           F   +Y  Q      RK+R  + E +L     S+ D+  L+K +   E   +R++R ++ 
Sbjct: 147 FFLDHYFEQLHYLYTRKQRARLFEEQLLKEPDSRRDE--LVKRYNGRERVYLRKRRTRIS 204

Query: 112 ADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKSEMLRRGQVEYVKSERNLLAEVD 171
             DF+ +T +G+G +G V + R++ T ++ A+K + KS + +  ++ +V +ER++L   +
Sbjct: 205 HGDFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSVLHKMDEIRHVLTERDILTTAN 264

Query: 172 SNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREVLTENEAKFYIGETVLAIESIHK 231
           S  +V+L  +FQD   +YL ME++PGGD  TLL    VL ++ AKFY  E  LAI+++H+
Sbjct: 265 SEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRDHHAKFYATEMFLAIDALHQ 324

Query: 232 HNYIHRDIKPDNLLLDRNGHVKLSDFGLCKPLDCSNLQEKDLSDGVNRSGVLQSDELTLS 291
             YIHRD+KP+N L+  +GH+KL+DFGL   +    + +K +     R   LQ     + 
Sbjct: 325 LGYIHRDLKPENFLVGASGHIKLTDFGLSSGI----ISKKKIESMKIR---LQEVNNVVV 377

Query: 292 PNQSQQQQLEHWRK--NHSRMLAYSTVGTPDYIAPEVILKRGYGVECDWWSLGAIMYEML 349
           P +S +++ + +R   +   + A+S VG+PDY+APEV+    Y    D+WSLG IMYE L
Sbjct: 378 PERSMRERRQVFRTLLSQDPVYAHSVVGSPDYMAPEVLRGENYNHSVDYWSLGCIMYECL 437

Query: 350 VGYPPFHSDDPRTTCRKIAHWKTYLKFP--------KDKLSPEAKDLICRLLCNVKQRLG 401
            G+PPF   +   T   + +W+   + P        +     +A D +C  + + K R  
Sbjct: 438 SGFPPFSGSNVNETWSNLKNWRKCFQRPHYDDPRDLEFNWRDDAWDFVCHCITDPKDRFC 497

Query: 402 AKGADEIKAHPWFKVVEWEKL-YQMRAPFIPKVNDELDTRNFDKFEEEDQKT---EPSPK 457
           +    ++  HP+F  ++W+ +    R PF+P +N E+D   FD F  E+  +   E   K
Sbjct: 498 S--LKQVMQHPYFSKIDWKNVRTAYRPPFVPDLNSEIDAGYFDDFTNENDMSKYKEVHEK 555

Query: 458 AGPWRKMLQS----KDINFVGYTYKN 479
                 M+ +    K   F+G+T+++
Sbjct: 556 QAAIANMVNTFNKPKRNAFIGFTFRH 581


>DBFB_YEAST (P32328) Serine/threonine-protein kinase DBF20 (EC
           2.7.1.37)
          Length = 564

 Score =  233 bits (594), Expect = 1e-60
 Identities = 139/460 (30%), Positives = 239/460 (51%), Gaps = 18/460 (3%)

Query: 34  NEEPPSNETKLKVEAAKHFVESYYKNQKQ----NQQERKERRNILENKLADAEVSKEDKK 89
           +E    ++T+  V   + +   YY +        +Q  K+    LE + +   VS +   
Sbjct: 84  HERASQSKTQRVVNVCQLYFLDYYCDMFDYVISRRQRTKQVLRYLEQQRSVKNVSNKVLN 143

Query: 90  NLLKNFEEMETEIMRRQRLKMGADDFEPLTMIGKGAFGEVRICREKTTGQVYAMKKLQKS 149
                + + E E++R++RLK    DF+ LT +G+G +G+V + ++K + ++ A+K L K 
Sbjct: 144 EEWALYLQREHEVLRKRRLKPKHKDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKK 203

Query: 150 EMLRRGQVEYVKSERNLLAEVDSNCIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRREV 209
            + +  +  +V +ER++L    S+ +VKL  +FQD E LYL ME++PGGD  TLL+   +
Sbjct: 204 LLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRI 263

Query: 210 LTENEAKFYIGETVLAIESIHKHNYIHRDIKPDNLLLDRNGHVKLSDFGLCKPLDCSNLQ 269
           L    A+FYI E   A+ ++H+  Y HRD+KP+N L+D  GH+KL+DFGL      SN +
Sbjct: 264 LKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAG-TVSNER 322

Query: 270 EKDLSDGVNRSGVLQSDELTLSPNQSQQQQLEHWRKNHSRMLAYSTVGTPDYIAPEVILK 329
            + +   +     L+    T    + +++   + RK      A S VG+PDY+A EV+  
Sbjct: 323 IESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEIN-YANSMVGSPDYMALEVLEG 381

Query: 330 RGYGVECDWWSLGAIMYEMLVGYPPFHSDDPRTTCRKIAHWKTYLKFPKDK-----LSPE 384
           + Y    D+WSLG +++E LVGY PF       T   + +WK  L+ P+ +      S  
Sbjct: 382 KKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDR 441

Query: 385 AKDLICRLLCNVKQRLGAKGADEIKAHPWFKVVEWEKLYQMRAPFIPKVNDELDTRNFDK 444
             DLI RL+ +   R+  +  ++++   +F  + +E L     PFIP+++DE D   FD 
Sbjct: 442 TWDLITRLIADPINRV--RSFEQVRKMSYFAEINFETLRTSSPPFIPQLDDETDAGYFDD 499

Query: 445 FEEEDQKTEPSPKAGPWRKML-----QSKDINFVGYTYKN 479
           F  E+   + +       K+       + D   VG+T+++
Sbjct: 500 FTNEEDMAKYADVFKRQNKLSAMVDDSAVDSKLVGFTFRH 539


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.319    0.135    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,953,400
Number of Sequences: 164201
Number of extensions: 2856207
Number of successful extensions: 14784
Number of sequences better than 10.0: 1702
Number of HSP's better than 10.0 without gapping: 1456
Number of HSP's successfully gapped in prelim test: 250
Number of HSP's that attempted gapping in prelim test: 9862
Number of HSP's gapped (non-prelim): 3364
length of query: 542
length of database: 59,974,054
effective HSP length: 115
effective length of query: 427
effective length of database: 41,090,939
effective search space: 17545830953
effective search space used: 17545830953
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)