BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC134823.6 + phase: 0
(662 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
MFP_ORYSA (Q8W1L6) Peroxisomal fatty acid beta-oxidation multifu... 931 0.0
MFPA_CUCSA (Q39659) Glyoxysomal fatty acid beta-oxidation multif... 787 0.0
MFPA_BRANA (O49809) Glyoxysomal fatty acid beta-oxidation multif... 769 0.0
ECHP_RAT (P07896) Peroxisomal bifunctional enzyme (PBE) (PBFE) [... 361 3e-99
ECHP_HUMAN (Q08426) Peroxisomal bifunctional enzyme (PBE) (PBFE)... 360 5e-99
ECHP_CAVPO (P55100) Peroxisomal bifunctional enzyme (PBE) (PBFE)... 355 2e-97
ECHP_MOUSE (Q9DBM2) Peroxisomal bifunctional enzyme (PBE) (PBFE)... 346 1e-94
YFCX_ECOLI (P77399) Putative fatty acid oxidation complex alpha ... 341 3e-93
FAOB_PSEFR (P28793) Fatty oxidation complex alpha subunit [Inclu... 334 5e-91
ECHA_RAT (Q64428) Trifunctional enzyme alpha subunit, mitochondr... 331 4e-90
ECHA_HUMAN (P40939) Trifunctional enzyme alpha subunit, mitochon... 327 6e-89
ECHA_PIG (Q29554) Trifunctional enzyme alpha subunit, mitochondr... 323 7e-88
FADB_SALTI (Q8Z3C6) Fatty oxidation complex alpha subunit [Inclu... 319 1e-86
FADB_SALTY (Q9L6L5) Fatty oxidation complex alpha subunit [Inclu... 317 8e-86
FADB_YERPE (Q8ZAN0) Fatty oxidation complex alpha subunit [Inclu... 316 1e-85
FADB_ECO57 (Q8X8I2) Fatty oxidation complex alpha subunit [Inclu... 312 2e-84
FADB_ECOLI (P21177) Fatty oxidation complex alpha subunit [Inclu... 310 1e-83
HBD_CLOAB (P52041) 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.... 168 4e-41
HBD_CLOTS (P77851) 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.... 159 2e-38
PAAH_ECOLI (P76083) Probable 3-hydroxybutyryl-CoA dehydrogenase ... 155 2e-37
>MFP_ORYSA (Q8W1L6) Peroxisomal fatty acid beta-oxidation
multifunctional protein (MFP) [Includes: Enoyl-CoA
hydratase (EC 4.2.1.17); 3-2-trans-enoyl-CoA isomerase
(EC 5.3.3.8); 3-hydroxybutyryl-CoA epimerase (EC
5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase
Length = 725
Score = 931 bits (2405), Expect = 0.0
Identities = 455/662 (68%), Positives = 557/662 (83%), Gaps = 3/662 (0%)
Query: 3 SVKVDFEVGNDGVAVITMCNPPVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFS 62
+++V EVG DGVAV+T+CNPPVNAL II+GLK K+ EA R+DVKAIVLTG GG+F
Sbjct: 4 AIRVTMEVGADGVAVVTICNPPVNALHPIIIQGLKEKYAEAMDRDDVKAIVLTGAGGKFC 63
Query: 63 GGFDISVMQKVHQTGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLELAMGCHA 122
GGFDI+V +VH+TG+++L+PDVSVELV N +E KKP VAA++GLALGGGLEL MGCHA
Sbjct: 64 GGFDINVFTEVHKTGNVSLMPDVSVELVSNLMEAGKKPSVAAIQGLALGGGLELTMGCHA 123
Query: 123 RVAAPKAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDA 182
R++ P+AQLGLPELTLGIIPGFGGTQRLPRLVG KA+EMML SK ITA+EG++ GL+DA
Sbjct: 124 RISTPEAQLGLPELTLGIIPGFGGTQRLPRLVGLPKAIEMMLQSKFITAKEGKEGGLVDA 183
Query: 183 IVSPAELLKLSRQWALEIAEQRRPWIRSLHITDKLGS--DAREVLRTARQHVKKTAPHLP 240
+ SP EL+K+SR WALEIA R+PWIRSL TD+LGS +AR VL +ARQ KK A +LP
Sbjct: 184 LCSPDELIKMSRLWALEIANYRKPWIRSLARTDRLGSLSEARSVLNSARQQAKKVAANLP 243
Query: 241 QQQACIDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTISKIPGVTDIG 300
Q QAC+DV+E G+L GG++GVL+EA+VFK+LVLS T+K L+H FFAQR +K+PGVTD+
Sbjct: 244 QHQACLDVMEEGVLCGGHAGVLKEAKVFKELVLSPTSKALVHAFFAQRLTTKVPGVTDVQ 303
Query: 301 LKPRNVRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRGLVTRK 360
LKPR +RK AVIGGGLMGSGIATAL++ N V+LKEVN ++ Q+G K I AN+ GLV R
Sbjct: 304 LKPRKIRKVAVIGGGLMGSGIATALLVSNTSVVLKEVNPQFRQRGQKMIAANLEGLVKRG 363
Query: 361 KLTQQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHCILASN 420
LT+ K A+SLLKG LDY +FKDVDMVIEAVIEK+ LKQ IFSDLEK+CPPHCILA+N
Sbjct: 364 SLTKDKMNKAMSLLKGALDYCDFKDVDMVIEAVIEKIPLKQSIFSDLEKVCPPHCILATN 423
Query: 421 TSTIDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGKIIKKS 480
TSTIDLN++GEK +SQDR+IGAHFFSPAHIMPLLEIVRT KTS Q ILDL+TVGK+IKK
Sbjct: 424 TSTIDLNVVGEKTNSQDRIIGAHFFSPAHIMPLLEIVRTEKTSPQAILDLITVGKMIKKV 483
Query: 481 PVVVGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLISNFGLPMGPFQLQDLSGYGV 540
PVVVGNCTGFAVNRTFFPY QG+H L ++G+DVFRIDR+IS+FG+PMGPFQLQDL+GYGV
Sbjct: 484 PVVVGNCTGFAVNRTFFPYTQGSHLLVSIGIDVFRIDRVISSFGMPMGPFQLQDLAGYGV 543
Query: 541 AVAVGKEFAGSFAGRTFPTPLLDLLIKSGRNGKNNGKGYYIYEKGSKPKPDPSVLPIVEE 600
+ G +A +F R + L+DL++++GR GK+NGKGYY+YEKG KPKPDPSV +++E
Sbjct: 544 HCSKG-FYAAAFGTRNLDSNLVDLMVQNGRQGKSNGKGYYLYEKGGKPKPDPSVQVVIDE 602
Query: 601 SRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDIASVLGMSFPS 660
RR + MP GKP++++DQ+I+EMI FPVVNEACRV++E +VIRASDLDIAS+LGM FP
Sbjct: 603 YRRCAKTMPGGKPVTLSDQDILEMIFFPVVNEACRVMDENVVIRASDLDIASILGMGFPK 662
Query: 661 YR 662
+R
Sbjct: 663 FR 664
>MFPA_CUCSA (Q39659) Glyoxysomal fatty acid beta-oxidation
multifunctional protein MFP-a [Includes: Enoyl-CoA
hydratase (EC 4.2.1.17); 3-2-trans-enoyl-CoA isomerase
(EC 5.3.3.8); 3-hydroxybutyryl-CoA epimerase (EC
5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase
Length = 725
Score = 787 bits (2032), Expect = 0.0
Identities = 390/657 (59%), Positives = 504/657 (76%), Gaps = 3/657 (0%)
Query: 9 EVGNDGVAVITMCNPPVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFSGGFDIS 68
EVG DGVA+IT+ NPPVN+L+ ++ L++ +E+A RR+DVKAIV+TG G+FSGGFDI+
Sbjct: 12 EVGTDGVAIITIINPPVNSLSFDVLFSLRDSYEQALRRDDVKAIVVTGAKGKFSGGFDIT 71
Query: 69 VMQKVHQ-TGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARVAAP 127
+ G+ V ++S+E++ + E ++KP VAA++GLALGGGLE+AM CHAR++ P
Sbjct: 72 AFGVLQGGKGEQPNVRNISIEMITDIFEAARKPAVAAIDGLALGGGLEVAMACHARISTP 131
Query: 128 KAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIVSPA 187
AQLGLPEL LGIIPGFGGTQRLPRLVG SKA+EMMLTSKPI +E LGL+DAIV P
Sbjct: 132 TAQLGLPELQLGIIPGFGGTQRLPRLVGLSKALEMMLTSKPIKGQEAHSLGLVDAIVPPE 191
Query: 188 ELLKLSRQWALEIAEQRRPWIRSLHITDKLGS--DAREVLRTARQHVKKTAPHLPQQQAC 245
EL+ +R+WALEI E+RRPW+ SLH TDKL S +AR++ AR KK P+L AC
Sbjct: 192 ELINTARRWALEILERRRPWVHSLHRTDKLESLAEARKIFNLARAQAKKQYPNLKHTIAC 251
Query: 246 IDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTISKIPGVTDIGLKPRN 305
ID +E G++ G +G+ +EAE F+ L+ S+T K LIH+FFAQR+ +K+PGVTD+GL PR
Sbjct: 252 IDAVETGVVSGPRAGLWKEAEEFQGLLHSDTCKSLIHIFFAQRSTTKVPGVTDLGLVPRQ 311
Query: 306 VRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRGLVTRKKLTQQ 365
++K A++GGGLMGSGIATALIL N V+LKEVN ++LQ GI + AN++ V + +T +
Sbjct: 312 IKKVAIVGGGLMGSGIATALILSNYHVVLKEVNDKFLQAGIDRVRANLQSRVKKGNMTNE 371
Query: 366 KAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHCILASNTSTID 425
K E ++SLLKGVL+Y FKDVDMVIEAVIE VSLKQ IFSDLEK CPPHC+LA+NTSTID
Sbjct: 372 KFEKSISLLKGVLNYESFKDVDMVIEAVIENVSLKQQIFSDLEKYCPPHCMLATNTSTID 431
Query: 426 LNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGKIIKKSPVVVG 485
L +IGE+I S+DR+IGAHFFSPAHIMPLLEIVRT T+AQVI+DL+ VGK IKK+PVVVG
Sbjct: 432 LELIGERIKSRDRIIGAHFFSPAHIMPLLEIVRTKHTAAQVIVDLLDVGKNIKKTPVVVG 491
Query: 486 NCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLISNFGLPMGPFQLQDLSGYGVAVAVG 545
NCTGFAVNR FFPY+Q A LA GVD ++IDR IS FG+PMGPF+L DL G+GVA A
Sbjct: 492 NCTGFAVNRMFFPYSQAAILLAEHGVDPYQIDRAISKFGMPMGPFRLCDLVGFGVAAATA 551
Query: 546 KEFAGSFAGRTFPTPLLDLLIKSGRNGKNNGKGYYIYEKGSKPKPDPSVLPIVEESRRLS 605
+F +F RT+ + L+ L+ + G++ KG+Y+Y+K K P+P + +E++R S
Sbjct: 552 SQFVQAFPERTYKSMLIPLMQEDKNAGESTRKGFYVYDKNRKAGPNPELKKYIEKARNSS 611
Query: 606 NIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDIASVLGMSFPSYR 662
+ + K + +++IVEMI FPVVNEACRVL EGI ++A+DLDIA V+GM FPSYR
Sbjct: 612 GVSVDPKLTKLPEKDIVEMIFFPVVNEACRVLAEGIAVKAADLDIAGVMGMGFPSYR 668
>MFPA_BRANA (O49809) Glyoxysomal fatty acid beta-oxidation
multifunctional protein MFP-a [Includes: Enoyl-CoA
hydratase (EC 4.2.1.17); 3-2-trans-enoyl-CoA isomerase
(EC 5.3.3.8); 3-hydroxybutyryl-CoA epimerase (EC
5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase
Length = 725
Score = 770 bits (1987), Expect = 0.0
Identities = 381/657 (57%), Positives = 502/657 (75%), Gaps = 3/657 (0%)
Query: 9 EVGNDGVAVITMCNPPVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFSGGFDIS 68
EVG DGVAVIT+ NPPVN+L+ ++ LK+ +EEA RNDVKAIV+TG G+FSGGFDIS
Sbjct: 12 EVGADGVAVITLINPPVNSLSFDVLYSLKSNYEEALSRNDVKAIVVTGAKGKFSGGFDIS 71
Query: 69 VMQKVHQ-TGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARVAAP 127
++ + T V +S++++ + +E +KKP VAA++GLALGGGLEL+M CHAR++AP
Sbjct: 72 GFGEIQKGTMKEPKVGYISIDILTDLLEAAKKPSVAAIDGLALGGGLELSMACHARISAP 131
Query: 128 KAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIVSPA 187
AQLGLPEL LG+IPGFGGTQRLPRLVG +KA+EM+LTSKP+ AEEG LGLIDA+V PA
Sbjct: 132 GAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPA 191
Query: 188 ELLKLSRQWALEIAEQRRPWIRSLHITDKLG--SDAREVLRTARQHVKKTAPHLPQQQAC 245
ELL +R+WAL+IAE+R+PW+ S+ TDKL +ARE+L+ A+ ++ AP++ C
Sbjct: 192 ELLNAARRWALDIAERRKPWVSSVLKTDKLPPLGEAREILKFAKDQTRRQAPNMKHPLMC 251
Query: 246 IDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTISKIPGVTDIGLKPRN 305
++ +E GI+ G +G+ +EA+V +++ +T KGLIHVFF+QR +K+PGVTD GL PR
Sbjct: 252 LEAVEVGIVSGSRAGLEKEAQVGSEVINLDTTKGLIHVFFSQRGTTKVPGVTDRGLVPRK 311
Query: 306 VRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRGLVTRKKLTQQ 365
+ K A+IGGGLMGSGIATALIL N VILKEVN ++L+ GI ++AN++ V + K++++
Sbjct: 312 INKVAIIGGGLMGSGIATALILSNYSVILKEVNEKFLEAGIGRVKANLQSRVKKGKMSKE 371
Query: 366 KAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHCILASNTSTID 425
K E +SLLKG LDY F+DVDMVIEAVIE +SLKQ IF+DLEK CP HCILASNTSTID
Sbjct: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTID 431
Query: 426 LNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGKIIKKSPVVVG 485
LN IGE+ SQDR+IGAHFFSPAH+MPLLEIVRTN TSAQVI+DL+ VGK I+K+PVVVG
Sbjct: 432 LNKIGERTKSQDRIIGAHFFSPAHVMPLLEIVRTNHTSAQVIVDLLDVGKKIRKTPVVVG 491
Query: 486 NCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLISNFGLPMGPFQLQDLSGYGVAVAVG 545
NCTGFAVNR FFPY Q A FL G D + ID+ +S FG+PMGPF+L DL G+GVA+A
Sbjct: 492 NCTGFAVNRMFFPYTQAAMFLVEHGTDPYLIDKAVSKFGMPMGPFRLCDLVGFGVAIATA 551
Query: 546 KEFAGSFAGRTFPTPLLDLLIKSGRNGKNNGKGYYIYEKGSKPKPDPSVLPIVEESRRLS 605
+F +F RT+ + ++ L+ + R G+ KG+Y+Y+ K KPDP + ++++R +S
Sbjct: 552 TQFIENFPERTYKSMIIPLMQEDKRAGEATRKGFYLYDDRRKAKPDPEIKNYIDKARSVS 611
Query: 606 NIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDIASVLGMSFPSYR 662
P+ K ++++EI+EM FPVVNEACRV EGI ++A+DLDIA + GM FP YR
Sbjct: 612 GAKPDPKLEKLSEKEIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIFGMGFPPYR 668
>ECHP_RAT (P07896) Peroxisomal bifunctional enzyme (PBE) (PBFE)
[Includes: Enoyl-CoA hydratase (EC 4.2.1.17);
3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8);
3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]
Length = 721
Score = 361 bits (927), Expect = 3e-99
Identities = 227/667 (34%), Positives = 363/667 (54%), Gaps = 37/667 (5%)
Query: 15 VAVITMCNPPVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFSGGFDISVMQKVH 74
+A+I +CNPPVNA++ +IR ++N ++A + VKAIV+ G G F G DI
Sbjct: 10 LAMIRLCNPPVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIH------ 63
Query: 75 QTGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARVAAPKAQLGLP 134
G P +++ +V+ I+ +KPV+AA++G+ALGGGLELA+GCH R+A KA++GLP
Sbjct: 64 --GFSAFTPGLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLP 121
Query: 135 ELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIVSP---AELLK 191
E+TLGI+PG GTQ LPR+VG A++++ + K ++A+E +LG++DA+V E +K
Sbjct: 122 EVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDPVEEAIK 181
Query: 192 LSRQWALEIAEQRRPWIRSLHITDKLGSDAREVLRTARQHVKKTAPHLPQQQACIDVIEH 251
+++ + E RR + + + + S V A V+K P + + C+ I+
Sbjct: 182 FAQKIIDKPIEPRRIFNKPVPSLPNMDS----VFAEAIAKVRKQYPGVLAPETCVRSIQA 237
Query: 252 GILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTISKIPGVTDIGLKPRN---VRK 308
+ H G+ E ++F L S AK L + FFA+++ +K + K + V
Sbjct: 238 SVKHPYEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSANKWSTPSGASWKTASAQPVSS 297
Query: 309 AAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRGLVTRKKLTQQKAE 368
V+G G MG GIA + I V+ E + + L K I + +R Q +
Sbjct: 298 VGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQAS- 356
Query: 369 GALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHCILASNTSTIDLNI 428
A L+ E VD+V+EAV E ++LK+ +F++L +C P L +NTS ++++
Sbjct: 357 -AKPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALNVDD 415
Query: 429 IGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGKIIKKSPVVVGNCT 488
I VIG HFFSPAH+M LLE++ + +S I ++++ K I K VVVGNC
Sbjct: 416 IASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCY 475
Query: 489 GFAVNRTFFPYAQGAHFLANLGVDVFRIDRLISNFGLPMGPFQLQDLSGYGVA--VAVGK 546
GF NR PY FL G +D ++ FG MGPF++ DL+G V + G+
Sbjct: 476 GFVGNRMLAPYYNQGFFLLEEGSKPEDVDGVLEEFGFKMGPFRVSDLAGLDVGWKIRKGQ 535
Query: 547 EFAGSF---------AGRTFPTPLLDLLIKSGRNGKNNGKGYYIYEK--GSKPKPDPSVL 595
G G + +PL D+L ++GR G+ GKG+Y Y+K G KPDP +
Sbjct: 536 GLTGPSLPPGTPVRKRGNSRYSPLGDMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPWLS 595
Query: 596 PIVEESRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDIASVLG 655
+ + R + +I + +I+ +EI+E L+ ++NEA R+LEEG+ R +D+ + G
Sbjct: 596 TFLSQYREVHHI----EQRTISKEEILERCLYSLINEAFRILEEGMAARPEHIDVIYLHG 651
Query: 656 MSFPSYR 662
+P ++
Sbjct: 652 YGWPRHK 658
>ECHP_HUMAN (Q08426) Peroxisomal bifunctional enzyme (PBE) (PBFE)
[Includes: Enoyl-CoA hydratase (EC 4.2.1.17);
3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8);
3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]
Length = 722
Score = 360 bits (925), Expect = 5e-99
Identities = 234/671 (34%), Positives = 362/671 (53%), Gaps = 52/671 (7%)
Query: 12 NDGVAVITMCNPPVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFSGGFDISVMQ 71
++ +A+I + NPPVNA++ ++R +K ++A R + +KAIV+ G G+FS G DI
Sbjct: 7 HNALALIRLRNPPVNAISTTLLRDIKEGLQKAGRDHTIKAIVICGAEGKFSAGADIRGFS 66
Query: 72 KVHQTGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARVAAPKAQL 131
G I + VV+ I+ ++KPVVAA++G+A GGGLELA+GCH R+A AQ+
Sbjct: 67 APRTFGLI-------LGHVVDEIQRNEKPVVAAIQGMAFGGGLELALGCHYRIAHADAQV 119
Query: 132 GLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIVSP---AE 188
GLPE+TLG++PG GTQ LPRL G A++++ + + I A+E KLG++D +V+ E
Sbjct: 120 GLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEE 179
Query: 189 LLKLSRQWALEIAEQRRPW---IRSLHITDKLGSDAREVLRTARQHVKKTAPHLPQQQAC 245
++ +++ + + E RR I+SL D + S+A +L+ RQH P Q+AC
Sbjct: 180 AIRFAQRVSDQPLESRRLCNKPIQSLPNMDSIFSEA--LLKMRRQH-----PGCLAQEAC 232
Query: 246 IDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTISKIPGVTDIGLKP-- 303
+ ++ + + G+ +E E+F L+ S A+ L + FFA+R +K + K
Sbjct: 233 VRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTAS 292
Query: 304 -RNVRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRGLVTRKKL 362
R V V+G G MG GI + I VI + + L K I + + ++ +
Sbjct: 293 ARPVSSVGVVGLGTMGRGIVISFARARIPVIGVDSDKNQLATANKMITSVLEKEASKMQQ 352
Query: 363 TQQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHCILASNTS 422
+ G L + E VD+VIEAV E++SLK+ +F++L +C P L +NTS
Sbjct: 353 SGHPWSGPKPRLTSSVK--ELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTS 410
Query: 423 TIDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGKIIKKSPV 482
+D++ I VIG HFFSPAH+M LLE++ + +S I ++ + K IKK V
Sbjct: 411 ALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGV 470
Query: 483 VVGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLISNFGLPMGPFQLQDLSGYGVAV 542
VVGNC GF NR PY A+FL G +D+++ FG MGPF++ DL+G V
Sbjct: 471 VVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGW 530
Query: 543 AVGKEFAGSFAGRTFPT----------------PLLDLLIKSGRNGKNNGKGYYIYEK-- 584
K G T PT P+ D+L + GR G+ GKG+Y Y+K
Sbjct: 531 KSRKG-----QGLTGPTLLPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPL 585
Query: 585 GSKPKPDPSVLPIVEESRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIR 644
G KPDP + + R+ +I +P +I+ EI+E L+ ++NEA R+L EGI
Sbjct: 586 GRIHKPDPWLSTFLSRYRKPHHI----EPRTISQDEILERCLYSLINEAFRILGEGIAAS 641
Query: 645 ASDLDIASVLG 655
+D+ + G
Sbjct: 642 PEHIDVVYLHG 652
>ECHP_CAVPO (P55100) Peroxisomal bifunctional enzyme (PBE) (PBFE)
[Includes: Enoyl-CoA hydratase (EC 4.2.1.17);
3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8);
3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]
Length = 725
Score = 355 bits (911), Expect = 2e-97
Identities = 231/672 (34%), Positives = 364/672 (53%), Gaps = 43/672 (6%)
Query: 15 VAVITMCNPPVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFSGGFDISVMQKVH 74
+A+I + NPPVNA++ +I G+K ++A +K IV++G F G DI
Sbjct: 10 LALIRLRNPPVNAISPAVIHGIKEGLQKAMSDYTIKGIVISGANNIFCAGADIHGF---- 65
Query: 75 QTGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARVAAPKAQLGLP 134
+ ++ + +V+ ++ +KPVVAA++G+ALGGGLEL++GCH R+A +A++G P
Sbjct: 66 -SAPLSFGTGSGLGPIVDEMQRYEKPVVAAIQGMALGGGLELSLGCHYRIAHAEARIGFP 124
Query: 135 ELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIVSPA---ELLK 191
E+TLGI+PG GTQ LPRL+G A++++ + + ITA E KLG++D +V+ A E +K
Sbjct: 125 EVTLGILPGARGTQLLPRLIGVPAALDLITSGRHITAGEALKLGILDKVVNSAPVEEAIK 184
Query: 192 LSRQWALEIAEQRRPWIR---SLHITDKLGSDAREVLRTARQHVKKTAPHLPQQQACIDV 248
+++ + E RR R SL D + +A E +R RQH + AP + C+
Sbjct: 185 FAQKILNQPLEPRRILNRPVSSLPNMDAIFGEAVEKMR--RQHPGQLAP-----ETCVRS 237
Query: 249 IEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTISKIPGVTDIGLKP---RN 305
++ + + G+++E E+F L S AK L + FFA+R+ K + K R
Sbjct: 238 VQASVQYPYEGGIMKERELFLNLQHSGQAKALQYAFFAERSAPKWSTPSGASWKTAAARP 297
Query: 306 VRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVR--GLVTRKKLT 363
V V+G G MG GIA + I VI E + + L+ K I + + +R++
Sbjct: 298 VSSVGVLGLGTMGRGIAISFARVGIPVIAVESDPKQLETAQKLITSILEKEASKSRQQCG 357
Query: 364 QQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHCILASNTST 423
QQ++ + D A VD+V+EAV E ++LK+ +F++L +C P L +NTS
Sbjct: 358 QQRSGPKPRFSSSMKDLAS---VDLVVEAVFEDMNLKKRVFAELSAVCKPEAFLCTNTSA 414
Query: 424 IDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGKIIKKSPVV 483
+D++ I + +VIG HFFSPAH+M LLE++ + +S I ++ + K IKK VV
Sbjct: 415 LDVDEIATSTNRPQQVIGTHFFSPAHVMKLLEVIPSRHSSPTTIATVMDLAKKIKKVAVV 474
Query: 484 VGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLISNFGLPMGPFQLQDLSGYGVA-- 541
VGNC GF NR Y + +FL G ID+ + FG MGPF++ DL+G V
Sbjct: 475 VGNCYGFVGNRMLRSYYEQTNFLLEDGSKPEDIDQALEEFGFRMGPFRVSDLAGLDVGWK 534
Query: 542 VAVGKEFAGSFAGRTFP---------TPLLDLLIKSGRNGKNNGKGYYIYEK--GSKPKP 590
+ G+ G T P +P+ D+L + GR G+ G+G+Y Y+K G KP
Sbjct: 535 IRKGQGLTGPSLQGTAPARKRGNARYSPIADMLCELGRFGQKTGQGWYKYDKPLGRIHKP 594
Query: 591 DPSVLPIVEESRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDI 650
DP + + E R +I KP I EI+E L+ ++NEA R+L EGI +D+
Sbjct: 595 DPWLSKFLSEYRETHHI----KPRVIGRDEILERCLYALINEAFRILGEGIAASPEHIDV 650
Query: 651 ASVLGMSFPSYR 662
+ G +P ++
Sbjct: 651 IYLHGYGWPRHK 662
>ECHP_MOUSE (Q9DBM2) Peroxisomal bifunctional enzyme (PBE) (PBFE)
[Includes: Enoyl-CoA hydratase (EC 4.2.1.17);
3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8);
3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]
Length = 717
Score = 346 bits (888), Expect = 1e-94
Identities = 225/669 (33%), Positives = 361/669 (53%), Gaps = 47/669 (7%)
Query: 15 VAVITMCNPPVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFSGGFDISVMQKVH 74
+A+I +CNPPVNA++ +I ++N ++A+ + V+AIV+ G F G DI +
Sbjct: 10 LAMIRLCNPPVNAISPTVITEVRNGLQKASLDHTVRAIVICGANDNFCAGADIHGFKS-- 67
Query: 75 QTGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARVAAPKAQLGLP 134
TG +++ +V+ I+ +KPVVAA++G+ALGGGLELA+GCH R+A KA++G P
Sbjct: 68 PTG-------LTLGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFP 120
Query: 135 ELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIVSP---AELLK 191
E+ LGI+PG GTQ LPR+VG A++++ + + I+ +E KLG++D +V E +K
Sbjct: 121 EVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPVEEAIK 180
Query: 192 LSRQWALEIAEQRRPW---IRSLHITDKLGSDAREVLRTARQHVKKTAPHLPQQQACIDV 248
++ + E RR + SL D + ++A + + +Q+ + AP + C+
Sbjct: 181 FAQTVIGKPIEPRRILNKPVPSLPNMDSVFAEA--IAKVRKQYPGRLAP-----ETCVRS 233
Query: 249 IEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTISKIPGVTDIGLKPRN--- 305
++ + H + EA++F L S A+ L + FFA+++ +K + K +
Sbjct: 234 VQASVKHPYEVAIKEEAKLFMYLRGSGQARALQYAFFAEKSANKWSTPSGASWKTASAQP 293
Query: 306 VRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRGLVTRKKLTQQ 365
V V+G G MG GIA + I V+ E + + L K I + + K+ ++
Sbjct: 294 VSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLE-----KEASKS 348
Query: 366 KAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHCILASNTSTID 425
A L+ E VD+VIEAV E ++LK+ +F++L +C P L +NTS +D
Sbjct: 349 GQASAKPNLRFSSSTKELSSVDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALD 408
Query: 426 LNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGKIIKKSPVVVG 485
++ I VIG HFFSPAHIM LLE++ + +S I ++++ K I K VVVG
Sbjct: 409 VDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPTTIATVMSLSKRIGKIGVVVG 468
Query: 486 NCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLISNFGLPMGPFQLQDLSGYGVA--VA 543
NC GF NR PY +FL G +D ++ FG MGPF++ DL+G V V
Sbjct: 469 NCYGFVGNRMLAPYYNQGYFLIEEGSKPEGVDGVLEEFGFRMGPFRVSDLAGLDVGWKVR 528
Query: 544 VGKEFAGSF---------AGRTFPTPLLDLLIKSGRNGKNNGKGYYIYEK--GSKPKPDP 592
G+ G G T +P+ D+L ++GR G+ GKG+Y Y+K G KPDP
Sbjct: 529 KGQGLTGPSLPPGTPTRKRGNTRYSPIADMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDP 588
Query: 593 SVLPIVEESRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDIAS 652
+ + + R +I K SI+ +EI+E L+ ++NEA R+LEEG+ +D+
Sbjct: 589 WLSEFLSQYRETHHI----KQRSISKEEILERCLYSLINEAFRILEEGMAASPEHIDVIY 644
Query: 653 VLGMSFPSY 661
+ G +P +
Sbjct: 645 LHGYGWPRH 653
>YFCX_ECOLI (P77399) Putative fatty acid oxidation complex alpha
subunit [Includes: Enoyl-CoA hydratase (EC 4.2.1.17);
3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35);
3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3)]
Length = 714
Score = 341 bits (875), Expect = 3e-93
Identities = 222/664 (33%), Positives = 352/664 (52%), Gaps = 34/664 (5%)
Query: 13 DGVAVITMCNP--PVNALAIPIIRGLKNKFEEAARRNDVKAIV-LTGKGGRFSGGFDISV 69
D +AVIT+ P +N L ++ ++ +++ +V ++ K F G DI++
Sbjct: 14 DNIAVITIDVPGEKMNTLKAEFASQVRAIIKQLRENKELRGVVFVSAKPDNFIAGADINM 73
Query: 70 MQKVHQTGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARVAA--P 127
+ + + +L+ I V+AA+ G LGGGLELA+ CH RV P
Sbjct: 74 IGNCKTAQEAEALARQGQQLMAE-IHALPIQVIAAIHGACLGGGLELALACHGRVCTDDP 132
Query: 128 KAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIVSPA 187
K LGLPE+ LG++PG GGTQRLPRL+G S A+EM+LT K + A++ KLGL+D +V +
Sbjct: 133 KTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALEMILTGKQLRAKQALKLGLVDDVVPHS 192
Query: 188 ELLKLSRQWALEIAEQRRPWIRSLHITDKL--GSDAREVL--RTARQHVKKTAPHLPQQQ 243
LL+ A+E+A++ RP R L + +++ G R +L ++ KT + P +
Sbjct: 193 ILLEA----AVELAKKERPSSRPLPVRERILAGPLGRALLFKMVGKKTEHKTQGNYPATE 248
Query: 244 ACIDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTISKIPGVTDIGLKP 303
++V+E G+ G SG EA F +L ++ ++ L +FFA + K PG P
Sbjct: 249 RILEVVETGLAQGTSSGYDAEARAFGELAMTPQSQALRSIFFASTDVKKDPGSD---APP 305
Query: 304 RNVRKAAVIGGGLMGSGIA--TALILGNIRVILKEVNSEYLQKGIKTIEANVRGLVTRKK 361
+ ++GGGLMG GIA TA G I V +K++N + + +K + G V R+
Sbjct: 306 APLNSVGILGGGLMGGGIAYVTACKAG-IPVRIKDINPQGINHALKYSWDQLEGKVRRRH 364
Query: 362 LTQQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHCILASNT 421
L + + L+L+ G DY F D++IEAV E + LKQ + +++E+ C H I ASNT
Sbjct: 365 LKASERDKQLALISGTTDYRGFAHRDLIIEAVFENLELKQQMVAEVEQNCAAHTIFASNT 424
Query: 422 STIDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGKIIKKSP 481
S++ + I + ++VIG HFFSP MPL+EI+ TSAQ I V + K K+P
Sbjct: 425 SSLPIGDIAAHATRPEQVIGLHFFSPVEKMPLVEIIPHAGTSAQTIATTVKLAKKQGKTP 484
Query: 482 VVVGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLISNFGLPMGPFQLQDLSGYGVA 541
+VV + GF VNR PY A + G V ID + FG P+GP QL D G
Sbjct: 485 IVVRDKAGFYVNRILAPYINEAIRMLTQGERVEHIDAALVKFGFPVGPIQLLDEVGIDTG 544
Query: 542 VAVGKEFAGSFAGR-TFPTPLLDLLIKSGRNGKNNGKGYYIY-EKG--SKPKPDPSVLPI 597
+ ++ R + P ++ ++ R G+ NG+G+Y+Y +KG SK + DP++ P+
Sbjct: 545 TKIIPVLEAAYGERFSAPANVVSSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPL 604
Query: 598 VEESRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDIASVLGMS 657
+ G+ I+ ++ E + ++NEA R ++E ++ D DI +V G+
Sbjct: 605 I-------GTQGQGR---ISAPQVAERCVMLMLNEAVRCVDEQVIRSVRDGDIGAVFGIG 654
Query: 658 FPSY 661
FP +
Sbjct: 655 FPPF 658
>FAOB_PSEFR (P28793) Fatty oxidation complex alpha subunit
[Includes: Enoyl-CoA hydratase (EC 4.2.1.17);
Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC
5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35);
3-hydroxybutyryl-CoA epimerase (EC 5.1.2.
Length = 715
Score = 334 bits (856), Expect = 5e-91
Identities = 211/633 (33%), Positives = 329/633 (51%), Gaps = 36/633 (5%)
Query: 49 VKAIVLTGKGGRFSGGFDISVMQKVHQTGDITLVP-DVSVELVVNSIEDSKKPVVAAVEG 107
VK ++++ F G DI+ + + D L+ ++ + + ED P VAA+ G
Sbjct: 53 VKGVIVSSGKDVFIVGADITEFVENFKLPDAELIAGNLEANKIFSDFEDLNVPTVAAING 112
Query: 108 LALGGGLELAMGCHARVAAPKAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSK 167
+ALGGGLE+ + RV A A++GLPE+ LGI PGFGGT RLPRL+G AVE + + K
Sbjct: 113 IALGGGLEMCLAADFRVMADSAKIGLPEVKLGIYPGFGGTVRLPRLIGVDNAVEWIASGK 172
Query: 168 PITAEEGQKLGLIDAIVSP-------AELLKLSRQWALEIAEQRRPWIRSLHITDKLGSD 220
AE+ K+ +DA+V+ +L+K + L+ +R+P + L + +
Sbjct: 173 ENRAEDALKVSAVDAVVTADKLGAAALDLIKRAISGELDYKAKRQPKLEKLKLN---AIE 229
Query: 221 AREVLRTARQHVKKTA-PHLPQQQACIDVIEHGILHGGYSGVLREAEVFKKLVLSETAKG 279
TA+ V A P+ P I I+ G + EA F KL + +
Sbjct: 230 QMMAFETAKGFVAGQAGPNYPAPVEAIKTIQKAANFGRDKALEVEAAGFAKLAKTSASNC 289
Query: 280 LIHVFFAQRTISKIPGVTDIGLKPRNVRKAAVIGGGLMGSGIATALILGNIRVILKEVNS 339
LI +F + + K V D K +V++AAV+G G+MG GIA +++K++N
Sbjct: 290 LIGLFLNDQELKKKAKVYDKIAK--DVKQAAVLGAGIMGGGIAYQSASKGTPILMKDINE 347
Query: 340 EYLQKGIKTIEANVRGLVTRKKLTQQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSL 399
+++G+ + G V + ++T K L+ ++ L Y +F +VD+V+EAV+E +
Sbjct: 348 HGIEQGLAEAAKLLVGRVDKGRMTPAKMAEVLNGIRPTLSYGDFGNVDLVVEAVVENPKV 407
Query: 400 KQDIFSDLEKICPPHCILASNTSTIDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRT 459
KQ + +++E ILASNTSTI ++++ + + + +G HFF+P H+MPL+E++R
Sbjct: 408 KQAVLAEVENHVREDAILASNTSTISISLLAKALKRPENFVGMHFFNPVHMMPLVEVIRG 467
Query: 460 NKTSAQVILDLVTVGKIIKKSPVVVGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRL 519
K+S + V K + K+P+VV +C GF VNR FPY G L + GVD RID++
Sbjct: 468 EKSSDLAVATTVAYAKKMGKNPIVVNDCPGFLVNRVLFPYFGGFAKLVSAGVDFVRIDKV 527
Query: 520 ISNFGLPMGPFQLQDLSGYGVAVAVGKEFAGSFAGRTFP--TPLLDLLIKSGRNGKNNGK 577
+ FG PMGP L D+ G A F R +D L ++ R G+ NGK
Sbjct: 528 MEKFGWPMGPAYLMDVVGIDTGHHGRDVMAEGFPDRMKDDRRSAIDALYEAKRLGQKNGK 587
Query: 578 GYYIYEKGSKPKP----DPSVL----PIVEESRRLSNIMPNGKPISITDQEIVEMILFPV 629
G+Y YE K K D SVL PIV E R +TD++I+ ++ P+
Sbjct: 588 GFYAYEADKKGKQKKLVDSSVLEVLKPIVYEQR------------DVTDEDIINWMMIPL 635
Query: 630 VNEACRVLEEGIVIRASDLDIASVLGMSFPSYR 662
E R LE+GIV A++ D+ V G+ FP +R
Sbjct: 636 CLETVRCLEDGIVETAAEADMGLVYGIGFPLFR 668
>ECHA_RAT (Q64428) Trifunctional enzyme alpha subunit, mitochondrial
precursor (TP-alpha) [Includes: Long-chain enoyl-CoA
hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]
Length = 763
Score = 331 bits (848), Expect = 4e-90
Identities = 230/691 (33%), Positives = 355/691 (51%), Gaps = 47/691 (6%)
Query: 1 MASVKVDFEVGNDGVAVITMCNPPVNALAIPIIRGLKNKFEEAARR---NDV--KAIVLT 55
++ +++ V D VAVI + +P N+ + + ++++F E ND A++++
Sbjct: 36 LSRTHINYGVKGD-VAVIRINSP--NSKVNTLNKEVQSEFVEVMNEIWANDQIRSAVLIS 92
Query: 56 GKGGRFSGGFDISVMQKVHQTGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLE 115
K G F G DI+++ + + ++ +E S KPVVAA+ G LGGGLE
Sbjct: 93 SKPGCFVAGADINMLASCTTPQEAARISQEGQKMF-EKLEKSPKPVVAAISGSCLGGGLE 151
Query: 116 LAMGCHARVAAP--KAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEE 173
LA+ C R+A K LG+PE+ LGI+PG GGTQRLP++VG A +MMLT + I A+
Sbjct: 152 LAIACQYRIATKDRKTVLGVPEVLLGILPGAGGTQRLPKMVGVPAAFDMMLTGRNIRADR 211
Query: 174 GQKLGLIDAIVSPAE-------------LLKLSRQWALEIAEQRRPWIRSLHITDKLGSD 220
+K+GL+D +V P L +++ +A +A+++ +S + +KL S
Sbjct: 212 AKKMGLVDQLVDPLGPGIKSPEERTIEYLEEVAVNFAKGLADRKVSAKQSKGLMEKLTSY 271
Query: 221 AREV-------LRTARQHVKKTAPHL-PQQQACIDVIEHGILHGGYSGVLREAEVFKKLV 272
A + +T + VKK L P ID ++ G+ G +G L E+E F +L
Sbjct: 272 AMTIPLCLTTTFKTVEEKVKKQTKGLYPAPLKIIDAVKTGLEQGNDAGYLAESEKFGELA 331
Query: 273 LSETAKGLIHVFFAQRTISKIPGVTDIGLKPRNVRKAAVIGGGLMGSGIATALILGNIRV 332
L++ +K L+ ++ Q K G + V++ A++G GLMG+GIA + ++
Sbjct: 332 LTKESKALMGLYNGQVLCKK----NKFGAPQKTVQQLAILGAGLMGAGIAQVSVDKGLKT 387
Query: 333 ILKEVNSEYLQKGIKTIEANVRGLVTRKKLTQQKAEGALSLLKGVLDYAEFKDVDMVIEA 392
+LK+ L +G + + + V +K LT + + S L G LDY F+ DMVIEA
Sbjct: 388 LLKDTTVTGLGRGQQQVFKGLNDKVKKKALTSFERDSIFSNLIGQLDYKGFEKADMVIEA 447
Query: 393 VIEKVSLKQDIFSDLEKICPPHCILASNTSTIDLNIIGEKISSQDRVIGAHFFSPAHIMP 452
V E +++K + ++E + P HCI ASNTS + +N I ++VIG H+FSP M
Sbjct: 448 VFEDLAVKHKVLKEVESVTPEHCIFASNTSALPINQIAAVSQRPEKVIGMHYFSPVDKMQ 507
Query: 453 LLEIVRTNKTSAQVILDLVTVGKIIKKSPVVVGNCTGFAVNRTFFPYAQGAHFLANLGVD 512
LLEI+ T+KTS V VG K +VV + GF R P + GVD
Sbjct: 508 LLEIITTDKTSKDTTASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVD 567
Query: 513 VFRIDRLISNFGLPMGPFQLQDLSGYGVAVAV----GKEFAGSFAGRTFPTPLLDLLIKS 568
++D L + FG P+G L D G VA V GK F F G + LL L++
Sbjct: 568 PKKLDALTTGFGFPVGAATLADEVGIDVAQHVAEDLGKAFGERFGGGS--VELLKLMVSK 625
Query: 569 GRNGKNNGKGYYIYEKGSKPKPDPSVLPIVEESRRLSNIMPNGKPISITDQEIVEMILFP 628
G G+ +GKG+YIY+ GSK K S E L N+ KP +D++I ++
Sbjct: 626 GFLGRKSGKGFYIYQSGSKNKNLNS-----EIDNILVNLRLPAKPEVSSDEDIQYRVITR 680
Query: 629 VVNEACRVLEEGIVIRASDLDIASVLGMSFP 659
VNEA L+EGI+ + DI +V G+ FP
Sbjct: 681 FVNEAVLCLQEGILATPEEGDIGAVFGLGFP 711
>ECHA_HUMAN (P40939) Trifunctional enzyme alpha subunit,
mitochondrial precursor (TP-alpha) (78 kDa
gastrin-binding protein) [Includes: Long-chain enoyl-CoA
hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]
Length = 763
Score = 327 bits (838), Expect = 6e-89
Identities = 223/677 (32%), Positives = 348/677 (50%), Gaps = 40/677 (5%)
Query: 11 GNDGVAVITMCNPPVNALAIPIIRGLKNKFEEAARRNDVK-AIVLTGKGGRFSGGFDISV 69
G+ V I N VN L+ + E + ++ A++++ K G F G DI++
Sbjct: 47 GDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINM 106
Query: 70 MQKVHQTGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARVAAP-- 127
+ ++T + + +V +E S KP+VAA+ G LGGGLE+A+ C R+A
Sbjct: 107 LAACKTLQEVTQLSQ-EAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDR 165
Query: 128 KAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIVSPA 187
K LG PE+ LG +PG GGTQRLP++VG A++MMLT + I A+ +K+GL+D +V P
Sbjct: 166 KTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPL 225
Query: 188 E-------------LLKLSRQWALEIAEQRRPWIRSLHITDKLGSDA-------REVLRT 227
L +++ +A +A+++ R + +KL + A ++V +
Sbjct: 226 GPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKK 285
Query: 228 ARQHVKKTAPHL-PQQQACIDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFA 286
+ V+K L P IDV++ GI G +G L E++ F +LV+++ +K L+ ++
Sbjct: 286 VEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHG 345
Query: 287 QRTISKIPGVTDIGLKPRNVRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGI 346
Q K G ++V+ A++G GLMG+GIA + ++ ILK+ L +G
Sbjct: 346 QVLCKK----NKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQ 401
Query: 347 KTIEANVRGLVTRKKLTQQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSD 406
+ + + V +K LT + + S L G LDY F+ DMVIEAV E +SLK + +
Sbjct: 402 QQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKE 461
Query: 407 LEKICPPHCILASNTSTIDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQV 466
+E + P HCI ASNTS + ++ I ++VIG H+FSP M LLEI+ T KTS
Sbjct: 462 VEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDT 521
Query: 467 ILDLVTVGKIIKKSPVVVGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLISNFGLP 526
V VG K +VV + GF R P + GVD ++D L ++FG P
Sbjct: 522 SASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFP 581
Query: 527 MGPFQLQDLSGYGVAVAV----GKEFAGSFAGRTFPTPLLDLLIKSGRNGKNNGKGYYIY 582
+G L D G VA V GK F F G LL ++ G G+ +GKG+YIY
Sbjct: 582 VGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGN--PELLTQMVSKGFLGRKSGKGFYIY 639
Query: 583 EKGSKPKPDPSVLPIVEESRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIV 642
++G K K S + + S +L P +S +D++I ++ VNEA L+EGI+
Sbjct: 640 QEGVKRKDLNSDMDSILASLKL----PPKSEVS-SDEDIQFRLVTRFVNEAVMCLQEGIL 694
Query: 643 IRASDLDIASVLGMSFP 659
++ DI +V G+ FP
Sbjct: 695 ATPAEGDIGAVFGLGFP 711
>ECHA_PIG (Q29554) Trifunctional enzyme alpha subunit, mitochondrial
precursor (TP-alpha) (78 kDa gastrin-binding protein)
[Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17);
Long chain 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)]
Length = 763
Score = 323 bits (829), Expect = 7e-88
Identities = 218/677 (32%), Positives = 347/677 (51%), Gaps = 40/677 (5%)
Query: 11 GNDGVAVITMCNPPVNALAIPIIRGLKNKFEEAARRNDVK-AIVLTGKGGRFSGGFDISV 69
G+ V I N VN L + E + ++ A++++ K G F G DI++
Sbjct: 47 GDVAVIRINSPNSKVNTLGQELHSEFIEVMNEVWSSSQIRSAVLISSKPGCFIAGADINM 106
Query: 70 MQKVHQTGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARVAAP-- 127
+ + ++T + + +E S KP+VAA+ G LGGGLELA+ C R+A
Sbjct: 107 LSACTTSQEVTQISQ-EAQRTFEKLEKSTKPIVAAINGTCLGGGLELAISCQYRIATKDK 165
Query: 128 KAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIVSPA 187
K LG PE+ LGI+PG GGTQRLP++VG A +MMLT + I A++ +K+GL+D +V P
Sbjct: 166 KTVLGAPEVLLGILPGAGGTQRLPKMVGVPAAFDMMLTGRGIRADKAKKMGLVDQLVEPL 225
Query: 188 E-------------LLKLSRQWALEIAEQRRPWIRSLHITDKLGSDA-------REVLRT 227
L +++ +A +A+++ R + +KL S A +++ +
Sbjct: 226 GPGLKPPEERTIEYLEEVAVTFAKGLADKKISPKRDKGLVEKLTSYAMSIPFVRQQIYKK 285
Query: 228 ARQHVKKTAPHL-PQQQACIDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFA 286
+ V+K L P IDV++ GI G +G L E++ F +L +++ +K L+ ++
Sbjct: 286 VEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLSESQKFGELAMTKESKALMGLYRG 345
Query: 287 QRTISKIPGVTDIGLKPRNVRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGI 346
Q K G + V+ A++G GLMG+GIA + +++ ILK+ + L +G
Sbjct: 346 QTLCKK----NKFGAPQKEVKHLAILGAGLMGAGIAQVSVDKHLKTILKDASLPALGRGQ 401
Query: 347 KTIEANVRGLVTRKKLTQQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSD 406
+ + + V +K LT + + S L G LDY F+ DMVIEAV E++SLK + +
Sbjct: 402 QQVFKGLNDKVRKKALTSFERDSLFSNLTGQLDYQGFEKADMVIEAVFEELSLKHKVLKE 461
Query: 407 LEKICPPHCILASNTSTIDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQV 466
+E + P HC+ ASNTS + ++ I ++VIG H+FSP M LLEI+ T KTS
Sbjct: 462 VEAVIPDHCVFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDS 521
Query: 467 ILDLVTVGKIIKKSPVVVGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLISNFGLP 526
V VG K +VV + GF R P + GV ++D L ++FG P
Sbjct: 522 TASAVEVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVLRILQEGVGPKKLDSLTTSFGFP 581
Query: 527 MGPFQLQDLSGYGVAVAV----GKEFAGSFAGRTFPTPLLDLLIKSGRNGKNNGKGYYIY 582
+G L D G VA V GK F FAG +L +I G G+ +GKG+Y+Y
Sbjct: 582 VGAATLMDEVGMDVAKHVAENLGKIFGERFAGGNL--DVLKQMISKGFLGRKSGKGFYVY 639
Query: 583 EKGSKPKPDPSVLPIVEESRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIV 642
++G K + S + L+++ +P +D++I ++ VNEA L+EGI+
Sbjct: 640 QEGVKNRNVNS-----DTESILASLKIPSRPDISSDEDIQYRLVTRFVNEAVLCLQEGIL 694
Query: 643 IRASDLDIASVLGMSFP 659
++ DI +V G+ FP
Sbjct: 695 ATPAEGDIGAVFGLGFP 711
>FADB_SALTI (Q8Z3C6) Fatty oxidation complex alpha subunit
[Includes: Enoyl-CoA hydratase (EC 4.2.1.17);
Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC
5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35);
3-hydroxybutyryl-CoA epimerase (EC 5.1.2.
Length = 729
Score = 319 bits (818), Expect = 1e-86
Identities = 215/669 (32%), Positives = 336/669 (50%), Gaps = 36/669 (5%)
Query: 13 DGVAVITMCNP-PVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFSGGFDISVMQ 71
DG+A + P VN L + L E +++D+K ++L F G DI+
Sbjct: 15 DGIAELVFDAPGSVNKLDTATVASLGQALEVLEKQHDLKGLLLRSNKAAFIVGADITEFL 74
Query: 72 KVHQTGDITLVPDVSVEL-------VVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARV 124
+ LVP+ + V N +ED P +AAV G ALGGG E + R+
Sbjct: 75 SLF------LVPEEQLSQWLHFANSVFNRLEDLPVPTLAAVNGYALGGGCECVLATDYRL 128
Query: 125 AAPKAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIV 184
A P ++GLPE LGI+PGFGG+ RLPR++G A+E++ K + AE K+GL+D +V
Sbjct: 129 ATPDLRIGLPETKLGIMPGFGGSVRLPRMLGADSALEIIAAGKDVGAEHALKIGLVDGVV 188
Query: 185 SPAELLK----LSRQWA---LEIAEQRRPWIRSLHITDKLGSDAREVLRTARQHVKKTA- 236
+L++ + RQ L+ +R+P + L ++ +A A+ V +TA
Sbjct: 189 KQEKLIEGAIAVLRQAITGDLDWRAKRQPKLEPLKLSK---IEAAMSFTIAKGMVAQTAG 245
Query: 237 PHLPQQQACIDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTIS-KIPG 295
H P + IE G + E + F L + A+ L+ +F + + K
Sbjct: 246 KHYPAPMTAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKK 305
Query: 296 VTDIGLKPRNVRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRG 355
+T P+ +AAV+G G+MG GIA + VI+K++N + L G+ +
Sbjct: 306 LTKDIETPK---QAAVLGAGIMGGGIAYQSAWKGVPVIMKDINDKSLNLGMTEAAKLLNK 362
Query: 356 LVTRKKLTQQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHC 415
+ R K+ K G +S + LDYA F VD+V+EAV+E +K+ + ++ E+ P
Sbjct: 363 QLERGKIDGLKLAGVISTIHPTLDYAGFDRVDVVVEAVVENPKVKKAVLAETEQKVRPET 422
Query: 416 ILASNTSTIDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGK 475
+LASNTSTI + + + + G HFF+P H MPL+EI+R K+S + I +V
Sbjct: 423 VLASNTSTIPIGELASALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWAS 482
Query: 476 IIKKSPVVVGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLI-SNFGLPMGPFQLQD 534
+ K+P+VV NC GF VNR FPY G L G D ++D+++ FG PMGP L D
Sbjct: 483 KMGKTPIVVNNCPGFFVNRVLFPYFAGFSQLLRDGADFRKVDKVMEKQFGWPMGPAYLLD 542
Query: 535 LSGYGVAVAVGKEFAGSFAGRTFP--TPLLDLLIKSGRNGKNNGKGYYIYEKGSKPKPDP 592
+ G A A F R +D L + R G+ NG G++ Y++ SK KP
Sbjct: 543 VVGIDTAHHAQAVMAAGFPQRMQKEYRDAIDALFDASRFGQKNGLGFWRYKEDSKGKPKK 602
Query: 593 SVLPIVEESRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDIAS 652
V++ L+++ + S D EI+ ++ P++NE R LEEGI+ ++ D+A
Sbjct: 603 EEDAAVDD--LLASVSQTKRDFS--DDEIIARMMIPMINEVVRCLEEGIIASPAEADMAL 658
Query: 653 VLGMSFPSY 661
V G+ FP +
Sbjct: 659 VYGLGFPPF 667
>FADB_SALTY (Q9L6L5) Fatty oxidation complex alpha subunit
[Includes: Enoyl-CoA hydratase (EC 4.2.1.17);
Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC
5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35);
3-hydroxybutyryl-CoA epimerase (EC 5.1.2.
Length = 729
Score = 317 bits (811), Expect = 8e-86
Identities = 214/669 (31%), Positives = 336/669 (49%), Gaps = 36/669 (5%)
Query: 13 DGVAVITMCNP-PVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFSGGFDISVMQ 71
DG+A + P VN L + L E +++D+K ++L F G DI+
Sbjct: 15 DGIAELVFDAPGSVNKLDTATVASLGQALEVLEKQHDLKGLLLRSNKAAFIVGADITEFL 74
Query: 72 KVHQTGDITLVPDVSVEL-------VVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARV 124
+ LVP+ + V N +ED P +AAV G ALGGG E + R+
Sbjct: 75 SLF------LVPEEQLSQWLHFANSVFNRLEDLPVPTLAAVNGYALGGGCECVLATDYRL 128
Query: 125 AAPKAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIV 184
A P ++GLPE LGI+PGFGG+ RLPR++G A+E++ K + AE K+GL+D +V
Sbjct: 129 ATPDLRIGLPETKLGIMPGFGGSVRLPRMLGADSALEIIAAGKDVGAEHALKIGLVDGVV 188
Query: 185 SPAELLK----LSRQWA---LEIAEQRRPWIRSLHITDKLGSDAREVLRTARQHVKKTA- 236
+L++ + RQ L+ +R+P + L ++ +A A+ V +TA
Sbjct: 189 KQEKLIEGAIAVLRQAITGDLDWRAKRQPKLEPLKLSK---IEAAMSFTIAKGMVAQTAG 245
Query: 237 PHLPQQQACIDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTIS-KIPG 295
H P + IE G + E + F L + A+ L+ +F + + K
Sbjct: 246 KHYPAPMTAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKK 305
Query: 296 VTDIGLKPRNVRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRG 355
+T P+ +AAV+G G+MG GIA + VI+K++N + L G+ +
Sbjct: 306 LTKDIETPK---QAAVLGAGIMGGGIAYQSAWKGVPVIMKDINDKSLNLGMTEAAKLLNK 362
Query: 356 LVTRKKLTQQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHC 415
+ R K+ K G +S + LDYA F VD+V+EAV+E +K+ + ++ E+ P
Sbjct: 363 QLERGKIDGLKLAGVISTIHPTLDYAGFDRVDVVVEAVVENPKVKKAVLAETEQKVRPET 422
Query: 416 ILASNTSTIDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGK 475
+LASNTSTI + + + + G HFF+P H MPL+EI+R K+S + I +V
Sbjct: 423 VLASNTSTIPIGELASALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWAS 482
Query: 476 IIKKSPVVVGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLI-SNFGLPMGPFQLQD 534
+ K+P+VV +C GF VNR FPY G L G D ++D+++ FG PMGP L D
Sbjct: 483 KMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKVDKVMEKQFGWPMGPAYLLD 542
Query: 535 LSGYGVAVAVGKEFAGSFAGRTFP--TPLLDLLIKSGRNGKNNGKGYYIYEKGSKPKPDP 592
+ G A A F R +D L + R G+ NG G++ Y++ SK KP
Sbjct: 543 VVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDASRFGQKNGLGFWRYKEDSKGKPKK 602
Query: 593 SVLPIVEESRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDIAS 652
V++ L+++ + S D EI+ ++ P++NE R LEEGI+ ++ D+A
Sbjct: 603 EEDAAVDD--LLASVSQPKRDFS--DDEIIARMMIPMINEVVRCLEEGIIASPAEADMAL 658
Query: 653 VLGMSFPSY 661
V G+ FP +
Sbjct: 659 VYGLGFPPF 667
>FADB_YERPE (Q8ZAN0) Fatty oxidation complex alpha subunit
[Includes: Enoyl-CoA hydratase (EC 4.2.1.17);
Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC
5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35);
3-hydroxybutyryl-CoA epimerase (EC 5.1.2.
Length = 729
Score = 316 bits (809), Expect = 1e-85
Identities = 206/671 (30%), Positives = 335/671 (49%), Gaps = 40/671 (5%)
Query: 13 DGVAVITMCNP-PVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFSGGFDISVM- 70
+G+A + P VN L + L +++++K ++L G DI+
Sbjct: 15 NGIAELVFDAPGSVNKLDTKTVANLGEALNVLEKQSELKGLLLRSAKTALIVGADITEFL 74
Query: 71 -------QKVHQTGDITLVPDVSVELVVNSIEDSKKPVVAAVEGLALGGGLELAMGCHAR 123
+K+HQ V + N +ED P ++A+ G ALGGG E + R
Sbjct: 75 SLFNAPPEKLHQWL-------VFANTIFNRLEDLPVPTISAINGYALGGGCECILATDFR 127
Query: 124 VAAPKAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAI 183
+A+P+A++GLPE LGI+PGFGG+ RLPRL+G A+E++ T K +TA + K+GL+DA+
Sbjct: 128 IASPEARIGLPETKLGIMPGFGGSVRLPRLLGADSALEIIATGKDVTANDALKIGLVDAV 187
Query: 184 VSPAEL-------LKLSRQWALEIAEQRRPWIRSLHITDKLGSDAREVLRTARQHVKKTA 236
V P +L LK + L+ RRP + L + ++A A+ V + A
Sbjct: 188 VDPEKLVGSALTMLKQAIDGKLDWQAARRPKLEPLKLNP---TEAAMCFTIAKGRVMQVA 244
Query: 237 -PHLPQQQACIDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTISKIPG 295
H P + IE G + E F L S A+ L+ +F + +
Sbjct: 245 GKHYPAPLTAVKTIEAAAKFGRTEALNLETNSFVPLAGSNEARALVGIFLNDQYVKAQAK 304
Query: 296 VTDIGLKPRNVRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRG 355
G+ + AAV+G G+MG GIA L ++ VI+K++N L G+ +
Sbjct: 305 KLSKGVAAPKL--AAVLGAGIMGGGIAYQSALKSVPVIMKDINENSLDLGMNEAAKLLNK 362
Query: 356 LVTRKKLTQQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHC 415
+ R K+ K L+ ++ LDYA + +++EAV+E +K + +++E +
Sbjct: 363 QLERGKVDGLKMASILATIRPTLDYAGIERAQVIVEAVVENPKVKAAVLAEVEALIGEDT 422
Query: 416 ILASNTSTIDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGK 475
+LASNTSTI ++ + + + + G HFF+P H MPL+EI+R KTS + + +V
Sbjct: 423 VLASNTSTIPIDQLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGAKTSDKTLAAVVAYAT 482
Query: 476 IIKKSPVVVGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLI-SNFGLPMGPFQLQD 534
+ K+P+VV +C GF VNR FPY G L G D +ID+++ FG PMGP L D
Sbjct: 483 QMGKTPIVVNDCPGFFVNRVLFPYLAGFGMLVRDGGDFHQIDKVMEKQFGWPMGPAYLLD 542
Query: 535 LSGYGVAVAVGKEFAGSFAGRTFP--TPLLDLLIKSGRNGKNNGKGYYIYEKGSKPKPDP 592
+ G A A F R +D++ + R G+ NG+G+Y Y + +K KP
Sbjct: 543 VVGIDTAHHAQAVMAAGFPERMNKDYRDAVDVMFDNQRFGQKNGQGFYRYTQDAKGKPRK 602
Query: 593 SVLPIVEESRRLSNIMPN-GKPI-SITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDI 650
E ++ ++ +P+ +D++I+ + P++NE R LEEGI+ A++ D+
Sbjct: 603 ------ENDEQVDKLLAEISQPLQEFSDEDIIARTMIPMINEVVRCLEEGIIASAAEGDM 656
Query: 651 ASVLGMSFPSY 661
A V G+ FP +
Sbjct: 657 ALVYGLGFPPF 667
>FADB_ECO57 (Q8X8I2) Fatty oxidation complex alpha subunit
[Includes: Enoyl-CoA hydratase (EC 4.2.1.17);
Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC
5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35);
3-hydroxybutyryl-CoA epimerase (EC 5.1.2.
Length = 729
Score = 312 bits (800), Expect = 2e-84
Identities = 211/669 (31%), Positives = 338/669 (49%), Gaps = 36/669 (5%)
Query: 13 DGVAVITMCNP-PVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFSGGFDISVMQ 71
DG+A + P VN L + L +++D+K ++L F G DI+
Sbjct: 15 DGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFL 74
Query: 72 KVHQTGDITLVPDVSVEL-------VVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARV 124
+ LVP+ + V N +ED P +AAV G ALGGG E + R+
Sbjct: 75 SLF------LVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRL 128
Query: 125 AAPKAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIV 184
A P ++GLPE LGI+PGFGG+ R+PR++G A+E++ K + A++ K+GL+D +V
Sbjct: 129 ATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVV 188
Query: 185 SPAELLK----LSRQWA---LEIAEQRRPWIRSLHITDKLGSDAREVLRTARQHVKKTA- 236
+L++ + RQ L+ +R+P + L ++ +A A+ V +TA
Sbjct: 189 KAEKLIEGAMAILRQAINGDLDWKAKRQPKLEPLKLSK---IEATMSFTIAKGMVAQTAG 245
Query: 237 PHLPQQQACIDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTIS-KIPG 295
H P + IE G + E + F L + A+ L+ +F + + K
Sbjct: 246 KHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKK 305
Query: 296 VTDIGLKPRNVRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRG 355
+T P+ +AAV+G G+MG GIA + VI+K++N + L G+ +
Sbjct: 306 LTKDVETPK---QAAVLGAGIMGGGIAYQSAWKGVPVIMKDINDKSLALGMTEAAKLLNK 362
Query: 356 LVTRKKLTQQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHC 415
+ R K+ K G +S + LDYA F+ VD+V+EA++E +K+ + ++ E+ P
Sbjct: 363 QLERGKIDGLKLAGVISTIHPTLDYAGFERVDVVVEAIVENPKVKKAVLAETEQKVRPDT 422
Query: 416 ILASNTSTIDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGK 475
+LASNTSTI ++ + + + G HFF+P H MPL+EI+R K+S + I +V
Sbjct: 423 VLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWAS 482
Query: 476 IIKKSPVVVGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLI-SNFGLPMGPFQLQD 534
+ K+P+VV +C GF VNR FPY G L G D +ID+++ FG PMGP L D
Sbjct: 483 KMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLD 542
Query: 535 LSGYGVAVAVGKEFAGSFAGRTFP--TPLLDLLIKSGRNGKNNGKGYYIYEKGSKPKPDP 592
+ G A A F R +D L + R G+ NG G++ Y++ SK KP
Sbjct: 543 VVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWHYKEDSKGKPKK 602
Query: 593 SVLPIVEESRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDIAS 652
V++ L+ + + S ++EI+ ++ P+VNE R LEEGI+ ++ D+A
Sbjct: 603 EEDAAVDD--LLAEVSQPKRDFS--EEEIIARMMIPMVNEVVRCLEEGIIATPAEADMAL 658
Query: 653 VLGMSFPSY 661
V G+ FP +
Sbjct: 659 VYGLGFPPF 667
>FADB_ECOLI (P21177) Fatty oxidation complex alpha subunit
[Includes: Enoyl-CoA hydratase (EC 4.2.1.17);
Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC
5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35);
3-hydroxybutyryl-CoA epimerase (EC 5.1.2.
Length = 729
Score = 310 bits (793), Expect = 1e-83
Identities = 210/669 (31%), Positives = 334/669 (49%), Gaps = 36/669 (5%)
Query: 13 DGVAVITMCNP-PVNALAIPIIRGLKNKFEEAARRNDVKAIVLTGKGGRFSGGFDISVMQ 71
DG+A + P VN L + L +++D+K ++L F G DI+
Sbjct: 15 DGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFL 74
Query: 72 KVHQTGDITLVPDVSVEL-------VVNSIEDSKKPVVAAVEGLALGGGLELAMGCHARV 124
+ LVP+ + V N +ED P +AAV G ALGGG E + R+
Sbjct: 75 SLF------LVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRL 128
Query: 125 AAPKAQLGLPELTLGIIPGFGGTQRLPRLVGTSKAVEMMLTSKPITAEEGQKLGLIDAIV 184
A P ++GLPE LGI+PGFGG+ R+PR++G A+E++ K + A++ K+GL+D +V
Sbjct: 129 ATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVV 188
Query: 185 SPAEL-------LKLSRQWALEIAEQRRPWIRSLHITDKLGSDAREVLRTARQHVKKTA- 236
+L L+ + L+ +R+P + L ++ +A A+ V +TA
Sbjct: 189 KAEKLVEGAKAVLRQAINGDLDWKAKRQPKLEPLKLSK---IEATMSFTIAKGMVAQTAG 245
Query: 237 PHLPQQQACIDVIEHGILHGGYSGVLREAEVFKKLVLSETAKGLIHVFFAQRTIS-KIPG 295
H P + IE G + E + F L + A+ L+ +F + + K
Sbjct: 246 KHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKK 305
Query: 296 VTDIGLKPRNVRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRG 355
+T P+ +AAV+G G+MG GIA + V++K++N + L G+ +
Sbjct: 306 LTKDVETPK---QAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLLNK 362
Query: 356 LVTRKKLTQQKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHC 415
+ R K+ K G +S + LDYA F VD+V+EAV+E +K+ + ++ E+
Sbjct: 363 QLERGKIDGLKLAGVISTIHPTLDYAGFDRVDIVVEAVVENPKVKKAVLAETEQKVRQDT 422
Query: 416 ILASNTSTIDLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGK 475
+LASNTSTI ++ + + + G HFF+P H MPL+EI+R K+S + I +V
Sbjct: 423 VLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWAS 482
Query: 476 IIKKSPVVVGNCTGFAVNRTFFPYAQGAHFLANLGVDVFRIDRLI-SNFGLPMGPFQLQD 534
+ K+P+VV +C GF VNR FPY G L G D +ID+++ FG PMGP L D
Sbjct: 483 KMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLD 542
Query: 535 LSGYGVAVAVGKEFAGSFAGRTFP--TPLLDLLIKSGRNGKNNGKGYYIYEKGSKPKPDP 592
+ G A A F R +D L + R G+ NG G++ Y++ SK KP
Sbjct: 543 VVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKK 602
Query: 593 SVLPIVEESRRLSNIMPNGKPISITDQEIVEMILFPVVNEACRVLEEGIVIRASDLDIAS 652
VE+ L+ + + S ++EI+ ++ P+VNE R LEEGI+ ++ D+A
Sbjct: 603 EEDAAVED--LLAEVSQPKRDFS--EEEIIARMMIPMVNEVVRCLEEGIIATPAEADMAL 658
Query: 653 VLGMSFPSY 661
V G+ FP +
Sbjct: 659 VYGLGFPPF 667
>HBD_CLOAB (P52041) 3-hydroxybutyryl-CoA dehydrogenase (EC
1.1.1.157) (Beta-hydroxybutyryl-CoA dehydrogenase)
(BHBD)
Length = 282
Score = 168 bits (426), Expect = 4e-41
Identities = 96/284 (33%), Positives = 150/284 (52%), Gaps = 7/284 (2%)
Query: 306 VRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRGLVTRKKLTQQ 365
++K VIG G MGSGIA A V+L+++ E++ +G+ I N+ LV + K+ +
Sbjct: 1 MKKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKKGKIEEA 60
Query: 366 KAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHCILASNTSTID 425
L+ + G +D D D+VIEA +E++ +K+ IF+DL+ IC P ILASNTS++
Sbjct: 61 TKVEILTRISGTVDLNMAADCDLVIEAAVERMDIKKQIFADLDNICKPETILASNTSSLS 120
Query: 426 LNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGKIIKKSPVVVG 485
+ + D+VIG HFF+PA +M L+E++R TS + + I K PV V
Sbjct: 121 ITEVASATKRPDKVIGMHFFNPAPVMKLVEVIRGIATSQETFDAVKETSIAIGKDPVEVA 180
Query: 486 NCTGFAVNRTFFPYAQGAHFLANLGV----DVFRIDRLISNFGLPMGPFQLQDLSGYGVA 541
GF VNR P A + G+ D+ + +L +N PMGP +L D G +
Sbjct: 181 EAPGFVVNRILIPMINEAVGILAEGIASVEDIDKAMKLGANH--PMGPLELGDFIGLDIC 238
Query: 542 VAVGKEFAGSFAGRTF-PTPLLDLLIKSGRNGKNNGKGYYIYEK 584
+A+ + P LL +++G G+ +GKG+Y Y K
Sbjct: 239 LAIMDVLYSETGDSKYRPHTLLKKYVRAGWLGRKSGKGFYDYSK 282
Score = 32.7 bits (73), Expect = 3.1
Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 621 IVEMILFPVVNEACRVLEEGIVIRASDLDIASVLGMSFP 659
+V IL P++NEA +L EGI D+D A LG + P
Sbjct: 186 VVNRILIPMINEAVGILAEGIA-SVEDIDKAMKLGANHP 223
>HBD_CLOTS (P77851) 3-hydroxybutyryl-CoA dehydrogenase (EC
1.1.1.157) (Beta-hydroxybutyryl-CoA dehydrogenase)
(BHBD)
Length = 289
Score = 159 bits (403), Expect = 2e-38
Identities = 93/281 (33%), Positives = 149/281 (52%), Gaps = 4/281 (1%)
Query: 306 VRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRGLVTRKKLTQQ 365
++K VIG G MGSGIA VIL++++ ++++KG TIE + ++T+ KL QQ
Sbjct: 1 MQKICVIGAGTMGSGIAQVFAQNGFEVILRDIDMKFVEKGFGTIEKIYKEMLTKGKL-QQ 59
Query: 366 KAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHCILASNTSTID 425
+ LS ++G + + K+ D V+EA IE + LK+ IF +L++IC ILASNTS++
Sbjct: 60 MRKRILSRIRGTTNLEDAKEADFVVEAAIENMDLKKQIFKELDEICKMETILASNTSSLS 119
Query: 426 LNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGKIIKKSPVVVG 485
+ I ++VIG HFF+P +M L+E+++ KTS Q + + + K+P+ V
Sbjct: 120 ITEIASATKRPEKVIGMHFFNPVPVMKLVEVIKGLKTSEQTFNVVRELALKVDKTPIEVK 179
Query: 486 NCTGFAVNRTFFPYAQGA--HFLANLGVDVFRIDRLISNFGLPMGPFQLQDLSGYGVAVA 543
GF VNR P A L D + + P+GP L L G V +A
Sbjct: 180 EAPGFVVNRILIPMINEAIGILAVVLATDKSIDEAMKLGANHPIGPLALSSLIGNDVVLA 239
Query: 544 VGKEFAGSFAGRTF-PTPLLDLLIKSGRNGKNNGKGYYIYE 583
+ + + P PLL +++ G G+ GKG++ Y+
Sbjct: 240 IMNVLYEEYGDSKYRPHPLLKKVVRGGLLGRKTGKGFFEYK 280
>PAAH_ECOLI (P76083) Probable 3-hydroxybutyryl-CoA dehydrogenase (EC
1.1.1.157) (Beta-hydroxybutyryl-CoA dehydrogenase)
(BHBD)
Length = 475
Score = 155 bits (393), Expect = 2e-37
Identities = 101/280 (36%), Positives = 144/280 (51%), Gaps = 4/280 (1%)
Query: 305 NVRKAAVIGGGLMGSGIATALILGNIRVILKEVNSEYLQKGIKTIEANVRGLVTRKKLTQ 364
NV+ AVIG G MG+GIA +V+L ++++E L + I I A + VTR KLT
Sbjct: 4 NVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTA 63
Query: 365 QKAEGALSLLKGVLDYAEFKDVDMVIEAVIEKVSLKQDIFSDLEKICPPHCILASNTSTI 424
+ E L L V D D+VIEA E++ +K+ +F+ L ++CPP +L +NTS+I
Sbjct: 64 ETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSI 123
Query: 425 DLNIIGEKISSQDRVIGAHFFSPAHIMPLLEIVRTNKTSAQVILDLVTVGKIIKKSPVVV 484
+ I +I + +RV G HFF+PA +M L+E+V T+A+V+ L + K PV
Sbjct: 124 SITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVRC 183
Query: 485 GNCTGFAVNRTFFPYAQGAHFLANLGVDVFRI--DRLISNFGLPMGPFQLQDLSGYGVAV 542
+ GF VNR PY A V + L G PMGP +L DL G V
Sbjct: 184 HSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQDVNF 243
Query: 543 AVGKEFAGSF--AGRTFPTPLLDLLIKSGRNGKNNGKGYY 580
AV +F R P+ + L+ GR GK +G G Y
Sbjct: 244 AVTCSVFNAFWQERRFLPSLVQQELVIGGRLGKKSGLGVY 283
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.320 0.139 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,479,577
Number of Sequences: 164201
Number of extensions: 3422260
Number of successful extensions: 10035
Number of sequences better than 10.0: 105
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 9789
Number of HSP's gapped (non-prelim): 117
length of query: 662
length of database: 59,974,054
effective HSP length: 117
effective length of query: 545
effective length of database: 40,762,537
effective search space: 22215582665
effective search space used: 22215582665
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Medicago: description of AC134823.6