BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC131239.17 + phase: 0 /pseudo
(892 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
PNK1_ARATH (Q8L5Y9) Probable pantothenate kinase 1 (EC 2.7.1.33)... 1487 0.0
PNK4_HUMAN (Q9NVE7) Pantothenate kinase 4 (EC 2.7.1.33) (Pantoth... 550 e-156
PNK4_RAT (Q923S8) Pantothenate kinase 4 (EC 2.7.1.33) (Pantothen... 532 e-150
PNK2_ARATH (O80765) Probable pantothenate kinase 2 (EC 2.7.1.33)... 457 e-128
PNK3_MOUSE (Q8R2W9) Pantothenate kinase 3 (EC 2.7.1.33) (Pantoth... 203 1e-51
PNK3_HUMAN (Q9H999) Pantothenate kinase 3 (EC 2.7.1.33) (Pantoth... 202 2e-51
PNK1_HUMAN (Q8TE04) Pantothenate kinase 1 (EC 2.7.1.33) (Pantoth... 201 9e-51
PNK1_MOUSE (Q8K4K6) Pantothenate kinase 1 (EC 2.7.1.33) (Pantoth... 199 2e-50
PNK2_HUMAN (Q9BZ23) Pantothenate kinase 2, mitochondrial precurs... 196 2e-49
CSLA_PEDHE (Q59288) Chondroitinase AC precursor (EC 4.2.2.5) (Ch... 36 0.52
GCP_HAEIN (P43764) Probable O-sialoglycoprotein endopeptidase (E... 35 1.2
FXJ1_RAT (Q63247) Forkhead box protein J1 (Hepatocyte nuclear fa... 32 7.5
TRA1_CLOPE (Q8XLQ0) tRNA pseudouridine synthase A 1 (EC 4.2.1.70... 32 9.8
ILD1_RHILO (Q98BZ8) Dihydroxy-acid dehydratase 1 (EC 4.2.1.9) (D... 32 9.8
>PNK1_ARATH (Q8L5Y9) Probable pantothenate kinase 1 (EC 2.7.1.33)
(Pantothenic acid kinase 1)
Length = 870
Score = 1487 bits (3849), Expect = 0.0
Identities = 745/868 (85%), Positives = 804/868 (91%), Gaps = 6/868 (0%)
Query: 29 MAPT--GNPIHRSSSRPQLDVSKAEIQSNVEDKYPTILLPNQSDDLSHLALDIGGSLIKL 86
MAP+ G PIHRS SRPQLD+SKAEIQ N+E++ PTILLPNQSDD+SHLALDIGGSLIKL
Sbjct: 1 MAPSTSGTPIHRSGSRPQLDLSKAEIQGNLEERDPTILLPNQSDDISHLALDIGGSLIKL 60
Query: 87 VYFSRHEGQS-DDDKRKKTLKERLGLSNGNRRSFPILGGRLHFVKFETGKINECLDFIHS 145
+YFSRHE S DDDKRK+T+KERLG++NGN RS+P+LGGRLHFVKFET KINECLDFIHS
Sbjct: 61 LYFSRHEDYSNDDDKRKRTIKERLGITNGNLRSYPVLGGRLHFVKFETHKINECLDFIHS 120
Query: 146 KQLHRGLESRYSD-TEADRNAIIKATGGGAYKFTDLFKEKLGVSLDKEDEMNCLVAGANF 204
KQLHR +S T +IK TGGGA+KF DLFKE+LGVS++KEDEM+CLV+GANF
Sbjct: 121 KQLHRRDPYPWSSKTLPLGTGVIKVTGGGAFKFADLFKERLGVSIEKEDEMHCLVSGANF 180
Query: 205 LLKAIRHEAFTHMEGQKEFVQIDQNDLFPYLLVNVGSGVSMIKVDGDGKFERVSGTNVGG 264
LLKAIRHEAFTHMEG+KEFVQID NDL+PYLLVNVGSGVS+IKVDG+GKFERVSGTNVGG
Sbjct: 181 LLKAIRHEAFTHMEGEKEFVQIDPNDLYPYLLVNVGSGVSIIKVDGEGKFERVSGTNVGG 240
Query: 265 GTYWGLGRLLTKCKSFDELLELSQKGDNRAIDMLVGDIYGGLDYSKIGLSASTIASSFGK 324
GTYWGLGRLLTKCKSFDELLELSQKGDN AIDMLVGDIYGG+DYSKIGLSASTIASSFGK
Sbjct: 241 GTYWGLGRLLTKCKSFDELLELSQKGDNSAIDMLVGDIYGGMDYSKIGLSASTIASSFGK 300
Query: 325 TISEKKELQDYRPEDISLSLLRMISYNIGQIAYLNALRFKLKRIFFGGFFIRGHAYTMDT 384
ISE KEL DYRPEDISLSLLRMISYNIGQI+YLNALRF LKRIFFGGFFIRGHAYTMDT
Sbjct: 301 AISENKELDDYRPEDISLSLLRMISYNIGQISYLNALRFGLKRIFFGGFFIRGHAYTMDT 360
Query: 385 LSFAVQYWSNGEAQAMFLRHEGFLGALGAFMSYEKHGLDDLMVHQLVERFPMGAPYTGGK 444
+SFAV +WS GE QAMFLRHEGFLGALGAFMSYEKHGLDDLM HQLVERFPMGAPYTGG
Sbjct: 361 ISFAVHFWSKGEMQAMFLRHEGFLGALGAFMSYEKHGLDDLMSHQLVERFPMGAPYTGGN 420
Query: 445 IHGPPLGDLNEKISWMEKFLQKGTEITAPVPMTPVAGTTGLGGFEVPLSKGSALRSDASA 504
IHGPPLGDL+EKISWMEKF+++GTEITAPVPMTP + TTGLGGFEVP S+GSALRSDASA
Sbjct: 421 IHGPPLGDLDEKISWMEKFVRRGTEITAPVPMTP-SKTTGLGGFEVPSSRGSALRSDASA 479
Query: 505 LNVGVLHLVPTLEVFPLLADPKLYEPNTIDLADPSELEYWLTILSEHLPDLVDKAVASEG 564
LNVGVLHLVPTLEVFPLLADPK YEPNTIDL+D E EYWL +LSEHLPDLVD AVASEG
Sbjct: 480 LNVGVLHLVPTLEVFPLLADPKTYEPNTIDLSDQGEREYWLKVLSEHLPDLVDTAVASEG 539
Query: 565 GTDDAKRRGDAFARAFSAHLSRLMEEPSAYGKLGLANLLEMREECLREFQFVDAYRSIKQ 624
GT+DAKRRGDAFARAFSAHL+RLMEEP+AYGKLGLANLLE+REECLREFQFVDAYRSIKQ
Sbjct: 540 GTEDAKRRGDAFARAFSAHLARLMEEPAAYGKLGLANLLELREECLREFQFVDAYRSIKQ 599
Query: 625 RENEASLAVLPDLFVELDSMDEETRLLTLIEGVLAANIFDWGSRACVDLYHKGTIIEIYR 684
RENEASLAVLPDL ELDSM EE RLLTLIEGVLAANIFDWGSRACVDLYHKGTIIEIYR
Sbjct: 600 RENEASLAVLPDLLEELDSMSEEARLLTLIEGVLAANIFDWGSRACVDLYHKGTIIEIYR 659
Query: 685 MSRNKMRRPWRVDDFDLFKERMLGTGDKKKAPHRRALLFVDNSGADIVLGMLPLARELLR 744
MSRNKM+RPWRVDDFD FKERMLG+G K+ H+RALLFVDNSGAD++LGMLPLARE LR
Sbjct: 660 MSRNKMQRPWRVDDFDAFKERMLGSGGKQPHRHKRALLFVDNSGADVILGMLPLAREFLR 719
Query: 745 RGTEVVLVANSLPALNDVTAMELPDIVAEAAKHCDILRRAAEAGGLLVDAMINT-DSSKE 803
RGTEVVLVANSLPALNDVTAMELPDIVA AAKHCDILRRAAE GGLLVDAM+N D SK+
Sbjct: 720 RGTEVVLVANSLPALNDVTAMELPDIVAGAAKHCDILRRAAEMGGLLVDAMVNPGDGSKK 779
Query: 804 NSSSVPLMVVENGCGSPCIDLRQVSSELAAAAKDADLIILEGMGRSLHTNLYAQFKCDAL 863
+S+S PLMVVENGCGSPCIDLRQVSSELAAAAKDADL++LEGMGR+LHTN AQF+C+AL
Sbjct: 780 DSTSAPLMVVENGCGSPCIDLRQVSSELAAAAKDADLVVLEGMGRALHTNFNAQFQCEAL 839
Query: 864 KLAMVKNQRLAEKLIKGNIYDCICKYQP 891
KLAMVKNQRLAEKLIKGNIYDC+C+Y+P
Sbjct: 840 KLAMVKNQRLAEKLIKGNIYDCVCRYEP 867
>PNK4_HUMAN (Q9NVE7) Pantothenate kinase 4 (EC 2.7.1.33)
(Pantothenic acid kinase 4) (hPanK4)
Length = 773
Score = 550 bits (1418), Expect = e-156
Identities = 335/836 (40%), Positives = 473/836 (56%), Gaps = 113/836 (13%)
Query: 70 DDLSHLALDIGGSLIKLVYFSRHEGQ-----SDDDKRKKTLKERLGLSNGNRRSFPI--- 121
++ A+DIGGSL KL Y+S + + S D K T +E + + I
Sbjct: 32 ENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSGKDTERE-------HEPPYEISVQ 84
Query: 122 --LGGRLHFVKFETGKINECLDFIHSKQLHRGLESRYSDTEADRNAIIKATGGGAYKFTD 179
+ RLHF+KFE I CLDFI + +TE +I+ATGGGAYKF D
Sbjct: 85 EEITARLHFIKFENTYIEACLDFI---------KDHLVNTETK---VIQATGGGAYKFKD 132
Query: 180 LFKEKLGVSLDKEDEMNCLVAGANFLLKAIRHEAFTHM-EGQKEF-VQIDQNDLFPYLLV 237
L +EKL + +DKED M CL+ G NF+LK I HEAF + + EF Q + +FPYLLV
Sbjct: 133 LIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLV 192
Query: 238 NVGSGVSMIKVDGDGKFERVSGTNVGGGTYWGLGRLLTKCKSFDELLELSQKGDNRAIDM 297
N+GSGVS++KV+ + +FE V G+++GGGT+WGLG LLTK K FDELL L+ +G + +DM
Sbjct: 193 NIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDM 252
Query: 298 LVGDIYGGLDYSKIGLSASTIASSFGKTISEKKELQDYRPEDISLSLLRMISYNIGQIAY 357
LV D+YGG + +GLS + IASSFGK+ + Q++ ED++ SLL MIS +IGQ+A
Sbjct: 253 LVRDVYGGA-HQTLGLSGNLIASSFGKSATAD---QEFSKEDMAKSLLHMISNDIGQLAC 308
Query: 358 LNALRFKLKRIFFGGFFIRGHAYTMDTLSFAVQYWSNGEAQAMFLRHEGFLGALGAFMSY 417
L+A L R++FGGFFIRGH TM T+++++ ++S GE QA+FLRHEG+LGA+GAF+
Sbjct: 309 LHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLK- 367
Query: 418 EKHGLDDLMVHQLVERFPMGAPYTGGKIHGPPLGDLNEKISWMEKFLQKGTEITAPVPMT 477
G + P + SW E +
Sbjct: 368 ------------------------GAEQDNP------NQYSWGENY-------------- 383
Query: 478 PVAGTTGLGGFEVPLSKGSALRSDASALNVGVLHLVPTLEVFPLLADPKLYEPNTIDLAD 537
AG++GL L RS L + + L L PLL DP Y P+T+DL D
Sbjct: 384 --AGSSGLMSASPELGPAQRARSGTFDL-LEMDRLERPLVDLPLLLDPPSYVPDTVDLTD 440
Query: 538 PS-ELEYWLTILSEHLPDLVDKAVASEGGTDDAKRRGDAFARAFSAHLSRLMEEPSAYGK 596
+ +YWLT E L +V +AVAS+ + DA R + F + + L L ++P AYG
Sbjct: 441 DALARKYWLTCFEEALDGVVKRAVASQPDSVDAAERAEKFRQKYWNKLQTLRQQPFAYGT 500
Query: 597 LGLANLLEMREECLREFQFVDAYRSIKQRENEASLAVLPDLFVELDSMDEETRLLTLIEG 656
L + +LL+ RE CL EF F D Y +KQREN +L P + LD++ E R L L++G
Sbjct: 501 LTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKG 560
Query: 657 VLAANIFDWGSRACVDLYHKGTIIEIYRMSRNKMRRPWRVDDFDLFKERMLGTGDKKKAP 716
+LA N+FDWG++A + R RPW VD + + +R+ G P
Sbjct: 561 LLAGNVFDWGAKAVSAVLESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKG------PP 614
Query: 717 HRRALLFVDNSGADIVLGMLPLARELLRRGTEVVLVANSLPALNDVTAMELPDIVAEAAK 776
H+ AL+F DNSG DI+LG+ P RELL RGTEV+L NS PALNDVT
Sbjct: 615 HKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVT------------- 661
Query: 777 HCDILRRAAEAGGLLVDAMINTDSSKENSSSVPLMVVENGCGSPCIDLRQVSSELAAAAK 836
H + L A G+ D ++++ +E L++V+ G SPC+DL ++ LAA +
Sbjct: 662 HSESLIVAERIAGM--DPVVHSALQEER-----LLLVQTGSSSPCLDLSRLDKGLAALVR 714
Query: 837 D--ADLIILEGMGRSLHTNLYAQFKCDALKLAMVKNQRLAEKLIKGNIYDCICKYQ 890
+ ADL+++EGMGR++HTN +A +C++LKLA++KN LAE+L G ++ I KY+
Sbjct: 715 ERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERL-GGRLFSVIFKYE 769
>PNK4_RAT (Q923S8) Pantothenate kinase 4 (EC 2.7.1.33) (Pantothenic
acid kinase 4) (rPanK4)
Length = 773
Score = 532 bits (1371), Expect = e-150
Identities = 330/838 (39%), Positives = 465/838 (55%), Gaps = 117/838 (13%)
Query: 70 DDLSHLALDIGGSLIKLVYFSR------------HEGQSDDDKRKKTLKERLGLSNGNRR 117
++ A+DIGGSL KL Y+S H G+ + + + +
Sbjct: 32 ENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHPGKDAEQDHEPPYEISVQEE----- 86
Query: 118 SFPILGGRLHFVKFETGKINECLDFIHSKQLHRGLESRYSDTEADRNAIIKATGGGAYKF 177
+ RLHF+KFE + CLDFI ++ +I+ATGGGAYKF
Sbjct: 87 ----ITARLHFIKFENTYMEACLDFIRDHLVNT------------ETKVIQATGGGAYKF 130
Query: 178 TDLFKEKLGVSLDKEDEMNCLVAGANFLLKAIRHEAFTHM-EGQKEF-VQIDQNDLFPYL 235
DL +EKL + +DKED M CL+ G NF+LK I HEAF + + EF Q + ++FPYL
Sbjct: 131 KDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYL 190
Query: 236 LVNVGSGVSMIKVDGDGKFERVSGTNVGGGTYWGLGRLLTKCKSFDELLELSQKGDNRAI 295
LVN+GSGVS++KV+ + +FE + G+++GGGT+WGLG LLTK K FDELL+L+ +G + +
Sbjct: 191 LVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANV 250
Query: 296 DMLVGDIYGGLDYSKIGLSASTIASSFGKTISEKKELQDYRPEDISLSLLRMISYNIGQI 355
DMLV DIYGG + +GLS + IASSFGK+ + +E + ED++ SLL MIS +IGQ+
Sbjct: 251 DMLVQDIYGGA-HQTLGLSGNLIASSFGKSATADRE---FSKEDMAKSLLHMISNDIGQL 306
Query: 356 AYLNALRFKLKRIFFGGFFIRGHAYTMDTLSFAVQYWSNGEAQAMFLRHEGFLGALGAFM 415
A L A L R++FGGFFIRGH TM T+++++ ++S GE QA+FLRHEG+LGA+GAF+
Sbjct: 307 ACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 366
Query: 416 SYEKHGLDDLMVHQLVERFPMGAPYTGGKIHGPPLGDLNEKISWMEKFLQKGTEITAPVP 475
G + P + SW E +
Sbjct: 367 K-------------------------GAEQDNP------NQYSWGENY------------ 383
Query: 476 MTPVAGTTGLGGFEVPLSKGSALRSDASALNVGVLHLVPTLEVFPLLADPKLYEPNTIDL 535
A ++GL L RS L + + L L PLL DP Y P+T+DL
Sbjct: 384 ----AASSGLMSTAPELCPTQRARSGTFDL-LEMDRLERPLVNLPLLLDPSSYVPDTVDL 438
Query: 536 ADPS-ELEYWLTILSEHLPDLVDKAVASEGGTDDAKRRGDAFARAFSAHLSRLMEEPSAY 594
D + +YWLT E L +V +AVAS+ + DA R + F + + L L +P AY
Sbjct: 439 TDDALARQYWLTCFEEALDGVVKRAVASQPESVDAAERAEKFRQKYWGKLQTLRHQPFAY 498
Query: 595 GKLGLANLLEMREECLREFQFVDAYRSIKQRENEASLAVLPDLFVELDSMDEETRLLTLI 654
G L + +LL+ RE CL EF F D Y +KQ+EN +L + LDS+ E R L L+
Sbjct: 499 GTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALV 558
Query: 655 EGVLAANIFDWGSRACVDLYHKGTIIEIYRMSRNKMRRPWRVDDFDLFKERMLGTGDKKK 714
+G+LA N+FDWG++A D+ R RPW VD + + +R+ G
Sbjct: 559 KGLLAGNVFDWGAKAVSDVLESDPQFGFEEAKRKLQERPWLVDSYTKWLQRLKG------ 612
Query: 715 APHRRALLFVDNSGADIVLGMLPLARELLRRGTEVVLVANSLPALNDVTAMELPDIVAEA 774
PH+ AL+F DNSG DI+LG+ P RELL RG EV+L NS PALNDVT E IVAE
Sbjct: 613 PPHKCALIFADNSGIDIILGVFPFVRELLCRGIEVILACNSGPALNDVTYSE-SLIVAE- 670
Query: 775 AKHCDILRRAAEAGGLLVDAMINTDSSKENSSSVPLMVVENGCGSPCIDLRQVSSELAAA 834
R AA +D +I T ++ L++V+ G PC+DL ++ LA
Sbjct: 671 -------RIAA------MDPIICTALREDR-----LLLVQTGSSPPCLDLSRLDKGLAVL 712
Query: 835 AKD--ADLIILEGMGRSLHTNLYAQFKCDALKLAMVKNQRLAEKLIKGNIYDCICKYQ 890
++ ADL+++EGMGR++HTN +A +C++LKLA+VKN LAE+L G ++ I KY+
Sbjct: 713 VRERGADLVVIEGMGRAVHTNYHALLRCESLKLAVVKNAWLAERL-GGQLFSVIFKYE 769
>PNK2_ARATH (O80765) Probable pantothenate kinase 2 (EC 2.7.1.33)
(Pantothenic acid kinase 2)
Length = 383
Score = 457 bits (1177), Expect = e-128
Identities = 234/357 (65%), Positives = 276/357 (76%), Gaps = 17/357 (4%)
Query: 72 LSHLALDIGGSLIKLVYFSRHEGQSDDDKRKKTLKERLGLSNGNRRSFPILGGRLHFVKF 131
+SHLALDIGG+LIKLVYFS + S++ +R ++ GRL F KF
Sbjct: 6 ISHLALDIGGTLIKLVYFSANGDYSEE----------------SRNGCSVVKGRLCFAKF 49
Query: 132 ETGKINECLDFIHSKQLHRGLESRYSDTEADRNAIIKATGGGAYKFTDLFKEKLGVSLDK 191
ET KI++CL+FI LH + + E +KATGGGA+KF DLFKEKLG+ DK
Sbjct: 50 ETRKIDDCLEFIRFNILHHS-GVQQPNGEGHDKLYVKATGGGAFKFADLFKEKLGILFDK 108
Query: 192 EDEMNCLVAGANFLLKAIRHEAFTHMEGQKEFVQIDQNDLFPYLLVNVGSGVSMIKVDGD 251
EDEM LV G NFLLK + EAFT+++GQK+FV+ID NDL+PYLLVN+GSGVSMIKVDGD
Sbjct: 109 EDEMCSLVGGVNFLLKTVPREAFTYLDGQKKFVEIDHNDLYPYLLVNIGSGVSMIKVDGD 168
Query: 252 GKFERVSGTNVGGGTYWGLGRLLTKCKSFDELLELSQKGDNRAIDMLVGDIYGGLDYSKI 311
GK+ER+SGT++GGGT+ GLG+LLTKCKSFDELLELS G+NR IDMLVGDIYGG DYSKI
Sbjct: 169 GKYERISGTSLGGGTFLGLGKLLTKCKSFDELLELSHHGNNRVIDMLVGDIYGGTDYSKI 228
Query: 312 GLSASTIASSFGKTISEKKELQDYRPEDISLSLLRMISYNIGQIAYLNALRFKLKRIFFG 371
GLS++ IASSFGK IS+ KEL+DY+PED++ SLLRMIS NIGQIAYLNALRF LKRIFFG
Sbjct: 229 GLSSTAIASSFGKAISDGKELEDYQPEDVARSLLRMISNNIGQIAYLNALRFGLKRIFFG 288
Query: 372 GFFIRGHAYTMDTLSFAVQYWSNGEAQAMFLRHEGFLGALGAFMSYEKHGLDDLMVH 428
GFFIRG YTMDT+S AV +WS GEA+AMFLRHEGFLGALGAF SY +DL H
Sbjct: 289 GFFIRGLEYTMDTISVAVHFWSRGEAKAMFLRHEGFLGALGAFTSYNDQSHNDLKPH 345
>PNK3_MOUSE (Q8R2W9) Pantothenate kinase 3 (EC 2.7.1.33)
(Pantothenic acid kinase 3) (mPanK3)
Length = 370
Score = 203 bits (517), Expect = 1e-51
Identities = 126/363 (34%), Positives = 206/363 (56%), Gaps = 38/363 (10%)
Query: 77 LDIGGSLIKLVYFSRHEGQSDDDKRK----KTLKERLGL-----SNGNR------RSFPI 121
+DIGG+L+KL YF + +++++ + K++++ L S G R + +
Sbjct: 16 MDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTL 75
Query: 122 LG--GRLHFVKFETGKINECLDFIHSKQLHRGLESRYSDTEADRNAIIKATGGGAYKFTD 179
G G LHF++F T + + G + +S + ++ ATGGGAYKF
Sbjct: 76 FGRRGNLHFIRFPTQDLPTFIQM--------GRDKNFSTLQT----VLSATGGGAYKFEK 123
Query: 180 LFKEKLGVSLDKEDEMNCLVAGANFLLKAI---RHEAFTHMEGQK----EFVQIDQNDLF 232
F+ + L K DE++CLV G ++ + E + + + + + +D +
Sbjct: 124 DFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLDDPY 183
Query: 233 PYLLVNVGSGVSMIKVDGDGKFERVSGTNVGGGTYWGLGRLLTKCKSFDELLELSQKGDN 292
P L+VN+GSGVS++ V ++RV+GT++GGGT+ GL LLT C+SF+E LE++ KGD+
Sbjct: 184 PLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDS 243
Query: 293 RAIDMLVGDIYGGLDYSKIGLSASTIASSFGKTISEKKELQDYRPEDISLSLLRMISYNI 352
D LV DIYGG DY + GL +ASSFG I ++K + ED++ + L I+ NI
Sbjct: 244 TQADRLVRDIYGG-DYERFGLPGWAVASSFGNMIYKEKR-ETVSKEDLARATLVTITNNI 301
Query: 353 GQIAYLNALRFKLKRIFFGGFFIRGHAYTMDTLSFAVQYWSNGEAQAMFLRHEGFLGALG 412
G +A + A+ K+ R+ F G F+R + +M L++A+ YWS G+ +A+FL HEG+ GA+G
Sbjct: 302 GSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVG 361
Query: 413 AFM 415
A +
Sbjct: 362 ALL 364
>PNK3_HUMAN (Q9H999) Pantothenate kinase 3 (EC 2.7.1.33)
(Pantothenic acid kinase 3) (hPanK3)
Length = 370
Score = 202 bits (515), Expect = 2e-51
Identities = 126/363 (34%), Positives = 206/363 (56%), Gaps = 38/363 (10%)
Query: 77 LDIGGSLIKLVYFSRHEGQSDDDKRK----KTLKERLGL-----SNGNR------RSFPI 121
+DIGG+L+KL YF + +++++ + K++++ L S G R + +
Sbjct: 16 MDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTL 75
Query: 122 LG--GRLHFVKFETGKINECLDFIHSKQLHRGLESRYSDTEADRNAIIKATGGGAYKFTD 179
G G LHF++F T + + G + +S + ++ ATGGGAYKF
Sbjct: 76 FGRRGNLHFIRFPTQDLPTFIQM--------GRDKNFSTLQT----VLCATGGGAYKFEK 123
Query: 180 LFKEKLGVSLDKEDEMNCLVAGANFLLKAI---RHEAFTHMEGQK----EFVQIDQNDLF 232
F+ + L K DE++CLV G ++ + E + + + + + +D +
Sbjct: 124 DFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLDDPY 183
Query: 233 PYLLVNVGSGVSMIKVDGDGKFERVSGTNVGGGTYWGLGRLLTKCKSFDELLELSQKGDN 292
P L+VN+GSGVS++ V ++RV+GT++GGGT+ GL LLT C+SF+E LE++ KGD+
Sbjct: 184 PLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDS 243
Query: 293 RAIDMLVGDIYGGLDYSKIGLSASTIASSFGKTISEKKELQDYRPEDISLSLLRMISYNI 352
D LV DIYGG DY + GL +ASSFG I ++K + ED++ + L I+ NI
Sbjct: 244 TQADKLVRDIYGG-DYERFGLPGWAVASSFGNMIYKEKR-ESVSKEDLARATLVTITNNI 301
Query: 353 GQIAYLNALRFKLKRIFFGGFFIRGHAYTMDTLSFAVQYWSNGEAQAMFLRHEGFLGALG 412
G +A + A+ K+ R+ F G F+R + +M L++A+ YWS G+ +A+FL HEG+ GA+G
Sbjct: 302 GSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVG 361
Query: 413 AFM 415
A +
Sbjct: 362 ALL 364
>PNK1_HUMAN (Q8TE04) Pantothenate kinase 1 (EC 2.7.1.33)
(Pantothenic acid kinase 1) (hPanK1) (hPanK)
Length = 598
Score = 201 bits (510), Expect = 9e-51
Identities = 128/369 (34%), Positives = 209/369 (55%), Gaps = 42/369 (11%)
Query: 77 LDIGGSLIKLVYFSRHEGQSDDDKRK----KTLKERLGLSNG-----------NRRSFPI 121
+DIGG+L+KLVYF + +++++ + K++++ L + ++ +
Sbjct: 241 MDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTM 300
Query: 122 LG--GRLHFVKFETGKINECLDFIHSKQLHRGLESRYSDTEADRNAIIKATGGGAYKFTD 179
G G LHF++F S +HR ++ + + + ATGGGA+KF +
Sbjct: 301 CGRKGNLHFIRFP------------SCAMHRFIQMGSEKNFSSLHTTLCATGGGAFKFEE 348
Query: 180 LFKEKLGVSLDKEDEMNCLVAGANFL--------LKAIRHEAFTHME-GQKEFVQIDQND 230
F+ + L K DE++CL+ G ++ + E T+ E QK+ +D
Sbjct: 349 DFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNP- 407
Query: 231 LFPYLLVNVGSGVSMIKVDGDGKFERVSGTNVGGGTYWGLGRLLTKCKSFDELLELSQKG 290
+P LLVN+GSGVS++ V ++RV+GT++GGGT+ GL LLT C++F+E LE++ KG
Sbjct: 408 -YPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKG 466
Query: 291 DNRAIDMLVGDIYGGLDYSKIGLSASTIASSFGKTISEKKELQDYRPEDISLSLLRMISY 350
D+ +D LV DIYGG DY + GL S +ASSFG +S++K ED++ + L I+
Sbjct: 467 DSTNVDKLVKDIYGG-DYERFGLQGSAVASSFGNMMSKEKR-DSISKEDLARATLVTITN 524
Query: 351 NIGQIAYLNALRFKLKRIFFGGFFIRGHAYTMDTLSFAVQYWSNGEAQAMFLRHEGFLGA 410
NIG IA + AL + R+ F G F+R + +M L++A+ +WS G+ +A+FL HEG+ GA
Sbjct: 525 NIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGA 584
Query: 411 LGAFMSYEK 419
+GA + K
Sbjct: 585 VGALLELFK 593
>PNK1_MOUSE (Q8K4K6) Pantothenate kinase 1 (EC 2.7.1.33)
(Pantothenic acid kinase 1) (mPank1) (mPank)
Length = 548
Score = 199 bits (507), Expect = 2e-50
Identities = 128/369 (34%), Positives = 211/369 (56%), Gaps = 42/369 (11%)
Query: 77 LDIGGSLIKLVYFSRHEGQSDDDKRK----KTLKERLGLSNG-----------NRRSFPI 121
+DIGG+L+KLVYF + +++++ + K++++ L + ++ +
Sbjct: 191 MDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTM 250
Query: 122 LG--GRLHFVKFETGKINECLDFIHSKQLHRGLESRYSDTEADRNAIIKATGGGAYKFTD 179
G G LHF++F T ++ + G E +S + + ATGGGA+KF +
Sbjct: 251 CGRKGNLHFIRFPTCAMHLFIQM--------GSEKNFSSL----HTTLCATGGGAFKFEE 298
Query: 180 LFKEKLGVSLDKEDEMNCLVAGANFL--------LKAIRHEAFTHME-GQKEFVQIDQND 230
F+ + L K DE++CL+ G ++ + E T+ E QK+ +D
Sbjct: 299 DFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNP- 357
Query: 231 LFPYLLVNVGSGVSMIKVDGDGKFERVSGTNVGGGTYWGLGRLLTKCKSFDELLELSQKG 290
+P LLVN+GSGVS++ V ++RV+GT++GGGT+ GL LLT C++F+E L+++ KG
Sbjct: 358 -YPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALDMAAKG 416
Query: 291 DNRAIDMLVGDIYGGLDYSKIGLSASTIASSFGKTISEKKELQDYRPEDISLSLLRMISY 350
D+ +D LV DIYGG DY + GL S +ASSFG +S++K + ED++ + L I+
Sbjct: 417 DSTNVDKLVKDIYGG-DYERFGLQGSAVASSFGNMMSKEKR-ESISKEDLARATLVTITN 474
Query: 351 NIGQIAYLNALRFKLKRIFFGGFFIRGHAYTMDTLSFAVQYWSNGEAQAMFLRHEGFLGA 410
NIG IA + AL + R+ F G F+R + +M L++A+ +WS G+ +A+FL HEG+ GA
Sbjct: 475 NIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGA 534
Query: 411 LGAFMSYEK 419
+GA + K
Sbjct: 535 VGALLELFK 543
>PNK2_HUMAN (Q9BZ23) Pantothenate kinase 2, mitochondrial precursor
(EC 2.7.1.33) (Pantothenic acid kinase 2) (hPANK2)
Length = 570
Score = 196 bits (498), Expect = 2e-49
Identities = 127/367 (34%), Positives = 206/367 (55%), Gaps = 38/367 (10%)
Query: 77 LDIGGSLIKLVYFSRHEGQSDDDKRK----KTLKERLGL-----SNGNR------RSFPI 121
LDIGG+L+KLVYF + +++++ + K++++ L S G R + +
Sbjct: 216 LDIGGTLVKLVYFEPKDITAEEEEEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTL 275
Query: 122 LG--GRLHFVKFETGKINECLDFIHSKQLHRGLESRYSDTEADRNAIIKATGGGAYKFTD 179
G G LHF++F T + + G + +S + + ATGGGAYKF
Sbjct: 276 CGRKGNLHFIRFPTHDMPAFIQM--------GRDKNFSSL----HTVFCATGGGAYKFEQ 323
Query: 180 LFKEKLGVSLDKEDEMNCLVAGANFLLKAI---RHEAF---THMEGQK-EFVQIDQNDLF 232
F + L K DE++CL+ G ++ R + + + +K + + D + +
Sbjct: 324 DFLTIGDLQLCKLDELDCLIKGILYIDSVGFNGRSQCYYFENPADSEKCQKLPFDLKNPY 383
Query: 233 PYLLVNVGSGVSMIKVDGDGKFERVSGTNVGGGTYWGLGRLLTKCKSFDELLELSQKGDN 292
P LLVN+GSGVS++ V ++RV+GT++GGGT++GL LLT C +F+E LE++ +GD+
Sbjct: 384 PLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFFGLCCLLTGCTTFEEALEMASRGDS 443
Query: 293 RAIDMLVGDIYGGLDYSKIGLSASTIASSFGKTISEKKELQDYRPEDISLSLLRMISYNI 352
+D LV DIYGG DY + GL +ASSFG +S++K + ED++ + L I+ NI
Sbjct: 444 TKVDKLVRDIYGG-DYERFGLPGWAVASSFGNMMSKEKR-EAVSKEDLARATLITITNNI 501
Query: 353 GQIAYLNALRFKLKRIFFGGFFIRGHAYTMDTLSFAVQYWSNGEAQAMFLRHEGFLGALG 412
G IA + AL + ++ F G F+R + M L++A+ YWS G+ +A+F HEG+ GA+G
Sbjct: 502 GSIARMCALNENINQVVFVGNFLRINTIAMRLLAYALDYWSKGQLKALFSEHEGYFGAVG 561
Query: 413 AFMSYEK 419
A + K
Sbjct: 562 ALLELLK 568
>CSLA_PEDHE (Q59288) Chondroitinase AC precursor (EC 4.2.2.5)
(Chondroitin AC lyase) (Chondroitin sulfate AC lyase)
(Chondroitin AC eliminase)
Length = 700
Score = 35.8 bits (81), Expect = 0.52
Identities = 21/68 (30%), Positives = 31/68 (44%), Gaps = 5/68 (7%)
Query: 377 GHAYTMDTLSFAVQYWSNGEAQAMFLRHEGF-----LGALGAFMSYEKHGLDDLMVHQLV 431
G D +S A +YW + + ++ H LG + M Y K LD+ +VH+L
Sbjct: 101 GDDKVFDQISKAFKYWYDSDPKSRNWWHNEIATPQALGEMLILMRYGKKPLDEALVHKLT 160
Query: 432 ERFPMGAP 439
ER G P
Sbjct: 161 ERMKRGEP 168
>GCP_HAEIN (P43764) Probable O-sialoglycoprotein endopeptidase (EC
3.4.24.57) (Glycoprotease)
Length = 342
Score = 34.7 bits (78), Expect = 1.2
Identities = 44/158 (27%), Positives = 69/158 (42%), Gaps = 16/158 (10%)
Query: 216 HMEGQKEFVQIDQNDL-FPYLLVNVGSG-VSMIKVDGDGKFERV--SGTNVGGGTYWGLG 271
HMEG +D N FP++ + V G +++VDG GK+E + S + G +
Sbjct: 111 HMEGHLLAPMLDDNSPHFPFVALLVSGGHTQLVRVDGVGKYEVIGESIDDAAGEAFDKTA 170
Query: 272 RLL-TKCKSFDELLELSQKG-DNRAIDMLVGDIYGGLDYSKIGLSASTIASSFGKTISEK 329
+LL L L++KG NR GLD+S GL + A++ + I +
Sbjct: 171 KLLGLDYPGGAALSRLAEKGTPNRFTFPRPMTDRAGLDFSFSGLK-TFAANTVNQAIKNE 229
Query: 330 KELQDYRPEDISLSLLRMISYNIGQIAYLNALRFKLKR 367
EL + DI+ + Q A ++ L K KR
Sbjct: 230 GELIEQTKADIAYAF---------QDAVVDTLAIKCKR 258
>FXJ1_RAT (Q63247) Forkhead box protein J1 (Hepatocyte nuclear
factor 3 forkhead homolog 4) (HFH-4)
Length = 421
Score = 32.0 bits (71), Expect = 7.5
Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 6/96 (6%)
Query: 442 GGKIHGPPLGDLNEKISWMEKFLQKGTEITAPVPMTPVAGTTGLGGFEVP--LSKGSALR 499
GG L D + W+++F + + A P P GT LG +VP ++ GS L
Sbjct: 21 GGMEEPDALDDSLTSLQWLQEF----SILNAKAPTLPPGGTDPLGYHQVPGLVAPGSPLA 76
Query: 500 SDASALNVGVLHLVPTLEVFPLLADPKLYEPNTIDL 535
+D + L PT A P L P D+
Sbjct: 77 ADPACLGQPHTPGKPTSSCTSRSAPPGLQAPPPDDV 112
>TRA1_CLOPE (Q8XLQ0) tRNA pseudouridine synthase A 1 (EC 4.2.1.70)
(Pseudouridylate synthase I 1) (Pseudouridine synthase I
1) (Uracil hydrolyase 1)
Length = 248
Score = 31.6 bits (70), Expect = 9.8
Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 176 KFTDLFKEKLGVSLDKEDEMNCLVAGANFLLKAIRHEAFTHMEGQKEFVQIDQNDLFPYL 235
KF D+F K ++++ ++ + GA +LL ++FT ++ + + N +
Sbjct: 122 KFKDVFLRKYAWHVEEKLDLEAMEEGAKYLLGTHDFKSFTSLKSKNKSTLRTINS----I 177
Query: 236 LVNVGSGVSMIKVDGDGKFERVSGTNVGGGTYWGLGRLLTKCKSFDELLELSQK 289
+ + + IK++G+G + VG GLG++ + K +++LE ++
Sbjct: 178 EFHENNNILSIKINGNGFLLNMVRIMVGTLVDVGLGKI--EPKYINDILEAKER 229
>ILD1_RHILO (Q98BZ8) Dihydroxy-acid dehydratase 1 (EC 4.2.1.9) (DAD
1)
Length = 614
Score = 31.6 bits (70), Expect = 9.8
Identities = 18/67 (26%), Positives = 32/67 (46%), Gaps = 1/67 (1%)
Query: 750 VLVANSLPALNDVTAMELPDIVAEAAKHCDILRRAAEAGGLLVDAMINTDSSKENSSSVP 809
+ ANS+ L + + LP + A H D R EAG L+VD + +++ +++P
Sbjct: 198 MFTANSMNCLTEALGLSLPGNGSTLATHADRKRLFVEAGHLIVD-LAQRYYEQDDETALP 256
Query: 810 LMVVENG 816
+ G
Sbjct: 257 RSIASKG 263
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.319 0.137 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,241,497
Number of Sequences: 164201
Number of extensions: 4789285
Number of successful extensions: 11364
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 11306
Number of HSP's gapped (non-prelim): 19
length of query: 892
length of database: 59,974,054
effective HSP length: 119
effective length of query: 773
effective length of database: 40,434,135
effective search space: 31255586355
effective search space used: 31255586355
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Medicago: description of AC131239.17