BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC126785.11 + phase: 0
(538 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
SVC2_RAT (Q9WTW8) Solute carrier family 23, member 2 (Sodium-dep... 291 4e-78
SVC2_MOUSE (Q9EPR4) Solute carrier family 23, member 2 (Sodium-d... 291 4e-78
SVC2_HUMAN (Q9UGH3) Solute carrier family 23, member 2 (Sodium-d... 288 3e-77
SVC1_MOUSE (Q9Z2J0) Solute carrier family 23, member 1 (Sodium-d... 273 1e-72
SVC1_RAT (Q9WTW7) Solute carrier family 23, member 1 (Sodium-dep... 272 1e-72
SVC1_HUMAN (Q9UHI7) Solute carrier family 23, member 1 (Sodium-d... 268 2e-71
YGFU_ECOLI (Q46821) Putative purine permease ygfU 119 2e-26
Y397_CLOPE (P50487) Putative purine permease CPE0397 115 2e-25
PUCK_BACSU (O32140) Uric acid permease pucK 113 1e-24
PUCJ_BACSU (O32139) Uric acid permease pucJ 106 2e-22
PBUX_BACSU (P42086) Xanthine permease 102 3e-21
URAA_ECOLI (P33780) Uracil permease (Uracil transporter) 77 9e-14
YWDJ_BACSU (P39618) Putative purine permease ywdJ 75 4e-13
PYRP_BACCL (P41006) Uracil permease (Uracil transporter) 71 8e-12
YCDG_ECOLI (P75892) Putative purine permease ycdG 70 2e-11
UAPC_EMENI (P48777) Purine permease 70 2e-11
URAA_PASMU (Q9CPL9) Probable uracil permease (Uracil transporter) 58 5e-08
URAA_HAEIN (P45117) Probable uracil permease (Uracil transporter) 57 9e-08
UAPA_EMENI (Q07307) Uric acid-xanthine permease (UAPA transporter) 56 2e-07
PYRP_BACSU (P39766) Uracil permease (Uracil transporter) 55 4e-07
>SVC2_RAT (Q9WTW8) Solute carrier family 23, member 2
(Sodium-dependent vitamin C transporter 2)
(Na(+)/L-ascorbic acid transporter 2)
Length = 592
Score = 291 bits (744), Expect = 4e-78
Identities = 178/539 (33%), Positives = 275/539 (50%), Gaps = 50/539 (9%)
Query: 27 QLPNVSYCITSPPPWPEAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKA--MLIQNH 84
Q ++ Y I PPW I LG QHYL T+ +P L M G+++ A LI
Sbjct: 29 QRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTI 88
Query: 85 LFVAGINTLIQTLFGTRLPAVIGGSFTFVPTTISIILASRYD----------------DD 128
F GI TL+QT FG RLP +F F+ +I+ ++ +
Sbjct: 89 FFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELLEH 148
Query: 129 IMHPREKFKRIMRGTQGALIVASSLQIIVGFSGLWCHVVRFISPLSAVPLVALTGFGLYE 188
I HPR ++ QGA+I++S +++++G GL ++R+I PL+ P VAL G ++
Sbjct: 149 IWHPR------IQEIQGAIIMSSLIEVVIGLLGLPGALLRYIGPLTITPTVALIGLSGFQ 202
Query: 189 LGFPMLAKCIEIGLPEIVILVFLSQFMPHMM---------KGGR----HIFARFAVIFSV 235
K I + I +++ SQ+ ++ KG +F F +I ++
Sbjct: 203 AAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAI 262
Query: 236 IIVWVYAIILTGCGAYKNAEHETQDTCRTD-RAGLIHGASWISPPIPFRWGAPTFDAGEA 294
++ W+ I T + + + RTD R G++ A W P PF+WG PT A
Sbjct: 263 LVSWLLCFIFTVTDVFPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGV 322
Query: 295 FAMMAASFVAQIESTGGFIAVARFASATPVPPSVLSRGIGWQGVGILLSGIFGTGNGSSV 354
M++A + IES G + A AR + A P P ++RGI +G+ +L G+FGTGNGS+
Sbjct: 323 IGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGVFGTGNGSTS 382
Query: 355 SIENAGLLALTRVGSRRVVQISAGFMIFFSILGKFGAVFASIPMPIVAALYCLLFSQVGS 414
S N G+L +T+VGSRRV+Q A M+ ++GKF A+FAS+P P++ AL+C LF + +
Sbjct: 383 SSPNIGVLGITKVGSRRVIQYGAALMLGLGMIGKFSALFASLPDPVLGALFCTLFGMITA 442
Query: 415 AGLSFLQFCNLNSFRTKFIIGFSIFMGFSVPQYFKEYTAIKQYGPVHTNARWFNDMINVP 474
GLS LQF +LNS R F++GFSIF G +P Y ++ P+ T + ++NV
Sbjct: 443 VGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQ-------NPLVTGITGIDQVLNVL 495
Query: 475 FSSGAFVAGILALFFDVTLHKSDNQTRKDRGMHWWDR-FSSFKTDTRSEEFYSLPFNLN 532
++ FV G +A D T+ T ++RG+ W + S E Y+LPF +N
Sbjct: 496 LTTAMFVGGCVAFILDNTI----PGTPEERGIKKWKKGVSKGNKSLDGMESYNLPFGMN 550
>SVC2_MOUSE (Q9EPR4) Solute carrier family 23, member 2
(Sodium-dependent vitamin C transporter 2) (mSVCT2)
(Na(+)/L-ascorbic acid transporter 2) (Yolk sac
permease-like molecule 2)
Length = 647
Score = 291 bits (744), Expect = 4e-78
Identities = 179/539 (33%), Positives = 275/539 (50%), Gaps = 50/539 (9%)
Query: 27 QLPNVSYCITSPPPWPEAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKA--MLIQNH 84
Q ++ Y I PPW I LG QHYL T+ +P L M G+++ A LI
Sbjct: 84 QRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTI 143
Query: 85 LFVAGINTLIQTLFGTRLPAVIGGSFTFVPTTISIILASRYD----------------DD 128
F GI TL+QT FG RLP +F F+ +I+ ++ +
Sbjct: 144 FFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELLEH 203
Query: 129 IMHPREKFKRIMRGTQGALIVASSLQIIVGFSGLWCHVVRFISPLSAVPLVALTGFGLYE 188
I HPR ++ QGA+I++S +++++G GL ++R+I PL+ P VAL G ++
Sbjct: 204 IWHPR------IQEIQGAIIMSSLIEVVIGLLGLPGALLRYIGPLTITPTVALIGLSGFQ 257
Query: 189 LGFPMLAKCIEIGLPEIVILVFLSQFMPHMM---------KGGR----HIFARFAVIFSV 235
K I + I +++ SQ+ ++ KG +F F +I ++
Sbjct: 258 AAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKFQLFKMFPIILAI 317
Query: 236 IIVWVYAIILTGCGAYKNAEHETQDTCRTD-RAGLIHGASWISPPIPFRWGAPTFDAGEA 294
++ W+ I T + + + RTD R G++ A W P PF+WG PT A
Sbjct: 318 LVSWLLCFIFTVTDVFPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGV 377
Query: 295 FAMMAASFVAQIESTGGFIAVARFASATPVPPSVLSRGIGWQGVGILLSGIFGTGNGSSV 354
M++A + IES G + A AR + A P P ++RGI +G+ +L GIFGTGNGS+
Sbjct: 378 IGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTS 437
Query: 355 SIENAGLLALTRVGSRRVVQISAGFMIFFSILGKFGAVFASIPMPIVAALYCLLFSQVGS 414
S N G+L +T+VGSRRV+Q A M+ ++GKF A+FAS+P P++ AL+C LF + +
Sbjct: 438 SSPNIGVLGITKVGSRRVIQYGAALMLGLGMVGKFSALFASLPDPVLGALFCTLFGMITA 497
Query: 415 AGLSFLQFCNLNSFRTKFIIGFSIFMGFSVPQYFKEYTAIKQYGPVHTNARWFNDMINVP 474
GLS LQF +LNS R F++GFSIF G +P Y ++ P+ T + ++NV
Sbjct: 498 VGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQ-------NPLVTGITGIDQILNVL 550
Query: 475 FSSGAFVAGILALFFDVTLHKSDNQTRKDRGMHWWDR-FSSFKTDTRSEEFYSLPFNLN 532
++ FV G +A D T+ T ++RG+ W + S E Y+LPF +N
Sbjct: 551 LTTAMFVGGCVAFILDNTI----PGTPEERGIKKWKKGVSKGSKSLDGMESYNLPFGMN 605
>SVC2_HUMAN (Q9UGH3) Solute carrier family 23, member 2
(Sodium-dependent vitamin C transporter 2) (hSVCT2)
(Na(+)/L-ascorbic acid transporter 2) (Yolk sac
permease-like molecule 2) (Nucleobase transporter-like 1
protein)
Length = 650
Score = 288 bits (736), Expect = 3e-77
Identities = 175/535 (32%), Positives = 272/535 (50%), Gaps = 40/535 (7%)
Query: 27 QLPNVSYCITSPPPWPEAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKA--MLIQNH 84
Q ++ Y I PPW I LG QHYL T+ +P L M G ++ A LI
Sbjct: 85 QRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTI 144
Query: 85 LFVAGINTLIQTLFGTRLPAVIGGSFTFVPTTISIILASRYD------------DDIMHP 132
F GI TL+QT FG RLP +F F+ +I+ ++ +++H
Sbjct: 145 FFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHT 204
Query: 133 REKFKRIMRGTQGALIVASSLQIIVGFSGLWCHVVRFISPLSAVPLVALTGFGLYELGFP 192
+ +R QGA+I++S +++++G GL ++++I PL+ P VAL G ++
Sbjct: 205 EHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGE 264
Query: 193 MLAKCIEIGLPEIVILVFLSQFMPHMM---------KGGR----HIFARFAVIFSVIIVW 239
K I + I +++ SQ+ ++ KG +F F +I ++++ W
Sbjct: 265 RAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSW 324
Query: 240 VYAIILTGCGAYKNAEHETQDTCRTD-RAGLIHGASWISPPIPFRWGAPTFDAGEAFAMM 298
+ I T + + RTD R G++ A W P PF+WG PT A M+
Sbjct: 325 LLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGML 384
Query: 299 AASFVAQIESTGGFIAVARFASATPVPPSVLSRGIGWQGVGILLSGIFGTGNGSSVSIEN 358
+A + IES G + A AR + A P P ++RGI +G+ +L GIFGTGNGS+ S N
Sbjct: 385 SAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPN 444
Query: 359 AGLLALTRVGSRRVVQISAGFMIFFSILGKFGAVFASIPMPIVAALYCLLFSQVGSAGLS 418
G+L +T+VGSRRV+Q A M+ ++GKF A+FAS+P P++ AL+C LF + + GLS
Sbjct: 445 IGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLS 504
Query: 419 FLQFCNLNSFRTKFIIGFSIFMGFSVPQYFKEYTAIKQYGPVHTNARWFNDMINVPFSSG 478
LQF +LNS R F++GFSIF G +P Y ++ P+ T + ++NV ++
Sbjct: 505 NLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQ-------NPLVTGITGIDQVLNVLLTTA 557
Query: 479 AFVAGILALFFDVTLHKSDNQTRKDRGMHWWDR-FSSFKTDTRSEEFYSLPFNLN 532
FV G +A D T+ T ++RG+ W + E Y+LPF +N
Sbjct: 558 MFVGGCVAFILDNTI----PGTPEERGIRKWKKGVGKGNKSLDGMESYNLPFGMN 608
>SVC1_MOUSE (Q9Z2J0) Solute carrier family 23, member 1
(Sodium-dependent vitamin C transporter 1)
(Na(+)/L-ascorbic acid transporter 1) (Yolk sac
permease-like molecule 3)
Length = 605
Score = 273 bits (697), Expect = 1e-72
Identities = 174/550 (31%), Positives = 271/550 (48%), Gaps = 50/550 (9%)
Query: 16 QDEFQPHPVKDQLPNVSYCITSPPPWPEAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNE 75
+D P P + + ++ Y I PPW I+LGFQHYL T+ +P L + G +
Sbjct: 24 RDRQAPLPTEPKF-DMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRD 82
Query: 76 EK--AMLIQNHLFVAGINTLIQTLFGTRLPAVIGGSFTFVPTTISIILASRYD------- 126
+ + LI GI TLIQT G RLP +F F+ SI+ R+
Sbjct: 83 QHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKSILALERWKCPSEEEI 142
Query: 127 ----------DDIMHPREKFKRIMRGTQGALIVASSLQIIVGFSGLWCHVVRFISPLSAV 176
I HPR +R QGA++V+S +++++G GL ++ +I PL+
Sbjct: 143 YGNWSMPLNTSHIWHPR------IREVQGAIMVSSMVEVVIGLMGLPGALLSYIGPLTVT 196
Query: 177 PLVALTGFGLYELGFPMLAKCIEIGLPEIVILVFLSQFMPHMM------KGGR------- 223
P V+L G +++ I I+++V SQ++ ++ + G+
Sbjct: 197 PTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRV 256
Query: 224 HIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDRAGLIHGAS-WISPPIPF 282
IF F ++ +++ VW+ +LT RTD G I S WI P P
Sbjct: 257 QIFKMFPIVLAIMTVWLLCYVLTLTDVLPADPTVYGFQARTDARGDIMAISPWIRIPYPC 316
Query: 283 RWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVPPSVLSRGIGWQGVGILL 342
+WG PT M +A+ IES G + A AR A A P P ++RGI +G+ ++
Sbjct: 317 QWGLPTVTVAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCII 376
Query: 343 SGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSILGKFGAVFASIPMPIVA 402
+G+ GTGNGS+ S N G+L +T+VGSRRVVQ AG M+ +GKF A+FAS+P PI+
Sbjct: 377 AGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGAIGKFTALFASLPDPILG 436
Query: 403 ALYCLLFSQVGSAGLSFLQFCNLNSFRTKFIIGFSIFMGFSVPQYFKEYTAIKQYGPVHT 462
++C LF + + GLS LQF ++NS R F++GFS+F G ++P Y G ++T
Sbjct: 437 GMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLD-----SNPGAINT 491
Query: 463 NARWFNDMINVPFSSGAFVAGILALFFDVTLHKSDNQTRKDRGMHWWDRFSSFKTDT-RS 521
+ ++ V ++ FV G LA D T+ S ++RG+ W + ++T S
Sbjct: 492 GIPEVDQILTVLLTTEMFVGGCLAFILDNTVPGSP----EERGLIQWKAGAHANSETSAS 547
Query: 522 EEFYSLPFNL 531
+ Y PF +
Sbjct: 548 LKSYDFPFGM 557
>SVC1_RAT (Q9WTW7) Solute carrier family 23, member 1
(Sodium-dependent vitamin C transporter 1)
(Na(+)/L-ascorbic acid transporter 1)
Length = 604
Score = 272 bits (696), Expect = 1e-72
Identities = 174/550 (31%), Positives = 272/550 (48%), Gaps = 50/550 (9%)
Query: 16 QDEFQPHPVKDQLPNVSYCITSPPPWPEAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNE 75
+D+ P P + + ++ Y I PPW I+LGFQHYL T+ +P L + G +
Sbjct: 24 RDQQAPLPAEPKF-DMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRD 82
Query: 76 EK--AMLIQNHLFVAGINTLIQTLFGTRLPAVIGGSFTFVPTTISIILASRYD------- 126
+ + LI GI TLIQT G RLP +F F+ +I+ R+
Sbjct: 83 QHMISQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEI 142
Query: 127 ----------DDIMHPREKFKRIMRGTQGALIVASSLQIIVGFSGLWCHVVRFISPLSAV 176
I HPR +R QGA++V+S +++++G GL ++ +I PL+
Sbjct: 143 YGNWSMPLNTSHIWHPR------IREVQGAIMVSSVVEVVIGLLGLPGALLSYIGPLTVT 196
Query: 177 PLVALTGFGLYELGFPMLAKCIEIGLPEIVILVFLSQFMPHMM------KGGR------- 223
P V+L G +++ I I+++V SQ++ ++ + G+
Sbjct: 197 PTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRI 256
Query: 224 HIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDRAGLIHGAS-WISPPIPF 282
IF F ++ +++ VW+ +LT RTD G I S WI P P
Sbjct: 257 QIFKMFPIVLAIMTVWLLCYVLTLTDVLPADPTVYGFQARTDARGDIMAISPWIRIPYPC 316
Query: 283 RWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVPPSVLSRGIGWQGVGILL 342
+WG PT M +A+ IES G + A AR A A P P ++RGI +GV ++
Sbjct: 317 QWGLPTVTVAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGVCCII 376
Query: 343 SGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSILGKFGAVFASIPMPIVA 402
+G+ GTGNGS+ S N G+L +T+VGSRRVVQ AG M+ +GKF A+FAS+P PI+
Sbjct: 377 AGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGAIGKFTALFASLPDPILG 436
Query: 403 ALYCLLFSQVGSAGLSFLQFCNLNSFRTKFIIGFSIFMGFSVPQYFKEYTAIKQYGPVHT 462
++C LF + + GLS LQF ++NS R F++GFS+F G ++P Y G ++T
Sbjct: 437 GMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLD-----SNPGAINT 491
Query: 463 NARWFNDMINVPFSSGAFVAGILALFFDVTLHKSDNQTRKDRGMHWWDRFSSFKTDT-RS 521
+ ++ V ++ FV G LA D T+ S ++RG+ W + ++T S
Sbjct: 492 GVPEVDQILTVLLTTEMFVGGCLAFILDNTVPGSP----EERGLIQWKAGAHANSETLAS 547
Query: 522 EEFYSLPFNL 531
+ Y PF +
Sbjct: 548 LKSYDFPFGM 557
>SVC1_HUMAN (Q9UHI7) Solute carrier family 23, member 1
(Sodium-dependent vitamin C transporter 1) (hSVCT1)
(Na(+)/L-ascorbic acid transporter 1) (Yolk sac
permease-like molecule 3)
Length = 598
Score = 268 bits (686), Expect = 2e-71
Identities = 171/550 (31%), Positives = 271/550 (49%), Gaps = 50/550 (9%)
Query: 16 QDEFQPHPVKDQLPNVSYCITSPPPWPEAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNE 75
+D P P + + ++ Y I PPW I+LGFQHYL T+ +P L + G++
Sbjct: 17 RDPSTPLPTEPKF-DMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHD 75
Query: 76 EK--AMLIQNHLFVAGINTLIQTLFGTRLPAVIGGSFTFVPTTISIILASRYD------- 126
+ + LI GI TLIQT G RLP +F F+ +I+ R+
Sbjct: 76 QHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEI 135
Query: 127 ----------DDIMHPREKFKRIMRGTQGALIVASSLQIIVGFSGLWCHVVRFISPLSAV 176
I HPR +R QGA++V+S +++++G GL ++ +I PL+
Sbjct: 136 YGNWSLPLNTSHIWHPR------IREVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVT 189
Query: 177 PLVALTGFGLYELGFPMLAKCIEIGLPEIVILVFLSQFMPHMM------KGGR------- 223
P V+L G +++ I I++++ SQ++ ++ + G+
Sbjct: 190 PTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRI 249
Query: 224 HIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDRAGLIHG-ASWISPPIPF 282
IF F ++ +++ VW+ +LT RTD G I A WI P P
Sbjct: 250 QIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPC 309
Query: 283 RWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVPPSVLSRGIGWQGVGILL 342
+WG PT A M +A+ IES G + A AR A A P P ++RGI +G+ ++
Sbjct: 310 QWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCII 369
Query: 343 SGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSILGKFGAVFASIPMPIVA 402
+G+ GTGNGS+ S N G+L +T+VGSRRVVQ A M+ +GKF A+FAS+P PI+
Sbjct: 370 AGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILG 429
Query: 403 ALYCLLFSQVGSAGLSFLQFCNLNSFRTKFIIGFSIFMGFSVPQYFKEYTAIKQYGPVHT 462
++C LF + + GLS LQF ++NS R F++GFS+F G ++P Y + G ++T
Sbjct: 430 GMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLE-----SNPGAINT 484
Query: 463 NARWFNDMINVPFSSGAFVAGILALFFDVTLHKSDNQTRKDRGMHWWDRFSSFKTDTRSE 522
+ ++ V ++ FV G LA D T+ S ++RG+ W + +D S
Sbjct: 485 GILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSP----EERGLIQWKAGAHANSDMSSS 540
Query: 523 -EFYSLPFNL 531
+ Y P +
Sbjct: 541 LKSYDFPIGM 550
>YGFU_ECOLI (Q46821) Putative purine permease ygfU
Length = 482
Score = 119 bits (299), Expect = 2e-26
Identities = 106/431 (24%), Positives = 182/431 (41%), Gaps = 59/431 (13%)
Query: 45 IMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLIQTL-----FG 99
I+LG QH LVM V +P + ++G E AMLI + LF GI TL+Q + G
Sbjct: 31 IILGLQHVLVMYAGAVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMG 90
Query: 100 TRLPAVIGGSFTFVPTTISIILASRYDDDIMHPREKFKRIMRGTQGALIVASSLQIIVGF 159
RLP ++ +F V I+I M+P I T A + + L ++G
Sbjct: 91 IRLPVIMSVTFAAVTPMIAIG---------MNPDIGLLGIFGATIAAGFITTLLAPLIG- 140
Query: 160 SGLWCHVVRFISPLSAVPLVALTGFGLYELGF---------PMLAKCIEIGLPEIVILVF 210
++ PL ++ G + ++G P + +G+ +L+F
Sbjct: 141 -----RLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYGNPVYLGI-SFAVLIF 194
Query: 211 LSQFMPHMMKGGRHIFARFAVIFSVIIVWVY-AIILTGCGAYKNAEHETQDTCRTDRAGL 269
+ + ++ ++F ++ W+ + L+G
Sbjct: 195 ILLITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSG---------------------- 232
Query: 270 IHGASWISPPIPFRWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVPPSVL 329
+H ASW + P +G P FD M A + IES G F+A+ ++
Sbjct: 233 LHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDII 292
Query: 330 SRGIGWQGVGILLSGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSILGKF 389
RG+ GVG ++ G F + +S S +N GL+++TRV SR V S +I F ++ K
Sbjct: 293 -RGLRVDGVGTMIGGTFNSFPHTSFS-QNVGLVSVTRVHSRWVCISSGIILILFGMVPKM 350
Query: 390 GAVFASIPMPIVAALYCLLFSQVGSAGLSFLQFCNLNSFR-TKFIIGFSIFMGFSVP--- 445
+ ASIP ++ ++F V + G+ L CN + R +I+ S+ +G +
Sbjct: 351 AVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISLGVGMTPTLSH 410
Query: 446 QYFKEYTAIKQ 456
+F + A+ Q
Sbjct: 411 DFFSKLPAVLQ 421
>Y397_CLOPE (P50487) Putative purine permease CPE0397
Length = 452
Score = 115 bits (289), Expect = 2e-25
Identities = 114/483 (23%), Positives = 203/483 (41%), Gaps = 63/483 (13%)
Query: 24 VKDQLPNVSYCITSPPPWPEAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQN 83
+K+ N+ Y + P+ ++ G QH G +++P + + +G ++ LI
Sbjct: 6 LKNTEVNLIYGVDDDLDLPKKVLFGLQHIFAAFGGIIVVPLVIATSLGFDSKVTTALISA 65
Query: 84 HLFVAGINTLIQTL----FGTRLPAVIGGSFTFVPTTISI--ILASRYDDDIMHPREKFK 137
+ +G+ T+IQ G R+ ++G FTFV IS+ +L
Sbjct: 66 SILGSGLATIIQAKGVGKVGARVACIMGTDFTFVSPAISVGSVLG--------------- 110
Query: 138 RIMRGTQGALIVASSLQIIVGFSGLWCHVVRFISPLSAVPLVALTGFGLYELGFPMLA-- 195
+ G GA I+ S ++I+ F +++F PL +VAL G L + A
Sbjct: 111 --LPGIIGATILGSLFEVILSF--FIKPLMKFFPPLVTGTVVALIGLTLLPVSIDWAAGG 166
Query: 196 --KCIEIGLPEIVILVFLSQFMPHMMKGGRHIFARFAVIFSVIIVWVYAIILTGCGAYKN 253
L + + +F+ + G+ + + +++ +++ ++ I L G +
Sbjct: 167 AGSANYASLENLAVAMFVLVITLLLNNYGKGMISSASILIGIVVGYIVCIPL-GLVDFTP 225
Query: 254 AEHETQDTCRTDRAGLIHGASWISPPIPFRWGAPTFDAGEAFAMMAASFVAQIESTGGFI 313
+ ASW+S P +G TFDA A + A FVA I + G
Sbjct: 226 VKE----------------ASWLSFPKILEFGV-TFDAKAVMAFIPAYFVATIGTVGCLK 268
Query: 314 AVARFASATPVPPSVLSRGIGWQGVGILLSGIFGTGNGSSVSIENAGLLALTRVGSRRVV 373
A+ S + ++ G+ GVG L G+ G+ +S S +N G+++LT+V SR V
Sbjct: 269 AIGE-TSNIDIGDKRVAAGVLSDGVGSALGGLVGSCPNTSFS-QNIGIISLTKVASRHVA 326
Query: 374 QISAGFMIFFSILGKFGAVFASIPMPIVAALYCLLFSQVGSAGLSFLQFCNLNSFRTKFI 433
++ ++ L K A+ IP P++ + ++F V +AG+ L L R I
Sbjct: 327 VMAGILLVILGFLPKVAAIITGIPNPVLGGVGIMMFGTVAAAGIRTLSNIKLTE-RNLLI 385
Query: 434 IGFSIFMGFSVPQYFKEYTAIKQYGPVHTNARWFNDMINVPFSSGAFVAGILALFFDVTL 493
I S+ +G V F+ +H + I + FSSG I AL + L
Sbjct: 386 IAISMGLGLGVT--FRP-------DVIHN----LPEAIRMIFSSGISTGTIAALILNAVL 432
Query: 494 HKS 496
+S
Sbjct: 433 KES 435
>PUCK_BACSU (O32140) Uric acid permease pucK
Length = 430
Score = 113 bits (283), Expect = 1e-24
Identities = 109/426 (25%), Positives = 184/426 (42%), Gaps = 65/426 (15%)
Query: 43 EAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLIQT----LF 98
+ +MLG QH L M +L+P + + +G + LI LF+ G TL+Q F
Sbjct: 9 QLMMLGLQHMLAMYAGAILVPLIVGAAIGLNAGQLTYLIAIDLFMCGAATLLQLWRNRYF 68
Query: 99 GTRLPAVIGGSFTFVPTTISIILASRYDDDIMHPREKFKRIMRGTQGALIVASSLQIIVG 158
G LP V+G +FT V ISI S Y ++ GA+I A + ++
Sbjct: 69 GIGLPVVLGCTFTAVGPMISI--GSTYGVPAIY-------------GAIIAAGLIVVLA- 112
Query: 159 FSGLWCHVVRFISPLSAVPLVALTGFGLYELGFPMLAK-------------CIEIGLPEI 205
+G + +VRF P+ +V + G L LA + G+
Sbjct: 113 -AGFFGKLVRFFPPVVTGSVVMIIGISLIPTAMNNLAGGEGSKEFGSLDNVLLGFGVTAF 171
Query: 206 VILVFLSQFMPHMMKGGRHIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTD 265
++L+F + KG F R I +I A G + D
Sbjct: 172 ILLLF------YFFKG----FIRSIAILLGLIAGTAAAYFMG---------------KVD 206
Query: 266 RAGLIHGASWISPPIPFRWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVP 325
+ ++ ASW+ P F +G PTF+ M+ + V+ +ESTG + A+A + +
Sbjct: 207 FSEVLE-ASWLHVPSLFYFGPPTFELPAVVTMLLVAIVSLVESTGVYFALADITNRR-LS 264
Query: 326 PSVLSRGIGWQGVGILLSGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSI 385
L +G +G+ ILL G+F ++ S +N G++ L+++ S V+ I+ ++ +
Sbjct: 265 EKDLEKGYRAEGLAILLGGLFNAFPYTAFS-QNVGIVQLSKMKSVNVIAITGIILVAIGL 323
Query: 386 LGKFGAVFASIPMPIVAALYCLLFSQVGSAGLSFLQFCNLNSFRTKFIIGFSIFMGF--- 442
+ K A+ IP P++ ++F V S G+ L +L+S II S+ +G
Sbjct: 324 VPKAAALTTVIPTPVLGGAMIVMFGMVISYGIKMLSSVDLDSQGNLLIIASSVSLGLGAT 383
Query: 443 SVPQYF 448
+VP F
Sbjct: 384 TVPALF 389
>PUCJ_BACSU (O32139) Uric acid permease pucJ
Length = 449
Score = 106 bits (264), Expect = 2e-22
Identities = 101/430 (23%), Positives = 180/430 (41%), Gaps = 66/430 (15%)
Query: 47 LGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLIQTLFGTR----L 102
L QH L M +L+P + + E+ + L+ L G+ TL+QTL GT L
Sbjct: 11 LSLQHVLAMYAGAILVPLLVGRALNVTTEQLSYLLAIDLLTCGVATLLQTLRGTYIGIGL 70
Query: 103 PAVIGGSFTFVPTTISIILASRYDDDIMHPREKFKRIMRGTQGALIVASSLQIIVGFSGL 162
P ++G SF V T I + S Y + G++I A + F+
Sbjct: 71 PVMLGSSF--VAVTPMIAIGSNYG-------------IHAIYGSIIAAGVFIFL--FARF 113
Query: 163 WCHVVRFISPLSAVPLVALTGFGLYELGFPMLA----------------KCIEIGLPEIV 206
+ + P+ +V L G L G +A + + + + +V
Sbjct: 114 FGKLTVLFPPVVTGTVVTLIGLSLVPTGVKNMAGGEKINGSANPEYGSLENLLLSVGVLV 173
Query: 207 ILVFLSQFMPHMMKGGRHIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDR 266
+++ L++F+ KG FAR + I A + G ++ +
Sbjct: 174 LILVLNRFL----KG----FARTLSVLIGIAAGTAAAAIMGKVSFSSVTE---------- 215
Query: 267 AGLIHGASWISPPIPFRWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVPP 326
A + P PF +GAP F+ G M+ V +ESTG F A+ + P+
Sbjct: 216 ------APFFQIPKPFYFGAPAFEIGPILTMLIVGIVIIVESTGVFYAIGKICGR-PLTD 268
Query: 327 SVLSRGIGWQGVGILLSGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSIL 386
L +G +G+ IL+ G+F ++ + +NAGLL LT+V +R +V + ++ ++
Sbjct: 269 KDLVKGYRAEGIAILIGGLFNAFPYNTFA-QNAGLLQLTKVKTRNIVVTAGCILVCLGLI 327
Query: 387 GKFGAVFASIPMPIVAALYCLLFSQVGSAGLSFLQFCNLNSFRTKFIIGFSIFMGF---S 443
K A+ +++P ++ ++F V ++G+ L +L + I SI +G +
Sbjct: 328 PKIAALASAVPAAVLGGATVVMFGMVIASGVKMLSTADLKNQYHLLTIACSIALGIGAST 387
Query: 444 VPQYFKEYTA 453
P F E+ A
Sbjct: 388 APGIFAEFPA 397
>PBUX_BACSU (P42086) Xanthine permease
Length = 438
Score = 102 bits (253), Expect = 3e-21
Identities = 99/426 (23%), Positives = 175/426 (40%), Gaps = 61/426 (14%)
Query: 43 EAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLIQT----LF 98
+ + LG QH L M +++P + MG E+ L+ +F+ G+ TL+Q F
Sbjct: 7 KTLSLGIQHVLAMYAGAIVVPLIVGKAMGLTVEQLTYLVSIDIFMCGVATLLQVWSNRFF 66
Query: 99 GTRLPAVIGGSFTFVPTTISIILASRYDDDIMHPREKFKRIMRGTQGALIVASSLQIIVG 158
G LP V+G +FT V I+I S Y ++ G++I + L I++
Sbjct: 67 GIGLPVVLGCTFTAVSPMIAI--GSEYGVSTVY-------------GSIIASGILVILIS 111
Query: 159 FSGLWCHVVRFISPLSAVPLVALTGFGLYELGFPMLA-----------KCIEIGLPEIVI 207
F + +V F P+ +V + G L + +A + + + I
Sbjct: 112 F--FFGKLVSFFPPVVTGSVVTIIGITLMPVAMNNMAGGEGSADFGDLSNLALAFTVLSI 169
Query: 208 LVFLSQFMPHMMKGGRHIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDRA 267
+V L +F KG F + I I++ + G + N
Sbjct: 170 IVLLYRFT----KG----FIKSVSILIGILIGTFIAYFMGKVQFDN-------------- 207
Query: 268 GLIHGASWISPPIPFRWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVPPS 327
+ A+ + PF +GAP+F A M + V+ +ESTG + A+ + +
Sbjct: 208 --VSDAAVVQMIQPFYFGAPSFHAAPIITMSIVAIVSLVESTGVYFALGDLTNRR-LTEI 264
Query: 328 VLSRGIGWQGVGILLSGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSILG 387
LS+G +G+ +LL GIF ++ S +N GL+ LT + V+ ++ ++ F +
Sbjct: 265 DLSKGYRAEGLAVLLGGIFNAFPYTAFS-QNVGLVQLTGIKKNAVIVVTGVILMAFGLFP 323
Query: 388 KFGAVFASIPMPIVAALYCLLFSQVGSAGLSFLQFCNLNSFRTKFIIGFSIFMGFS---V 444
K A IP ++ +F V + G+ L + I+ S+ +G V
Sbjct: 324 KIAAFTTIIPSAVLGGAMVAMFGMVIAYGIKMLSRIDFAKQENLLIVACSVGLGLGVTVV 383
Query: 445 PQYFKE 450
P FK+
Sbjct: 384 PDIFKQ 389
>URAA_ECOLI (P33780) Uracil permease (Uracil transporter)
Length = 429
Score = 77.4 bits (189), Expect = 9e-14
Identities = 91/392 (23%), Positives = 155/392 (39%), Gaps = 52/392 (13%)
Query: 35 ITSPPPWPEAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLI 94
++ PP + I L QH M G TVL+P N +L GI TL+
Sbjct: 8 VSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHI-----NPATVLLFN------GIGTLL 56
Query: 95 QTLFGT-RLPAVIGGSFTFVPTTISIILASRYDDDIMHPREKFKRIMRGTQGALIVASSL 153
++PA +G SF F+ + + ++L Y+ + G I+ L
Sbjct: 57 YLFICKGKIPAYLGSSFAFI-SPVLLLLPLGYEVAL---------------GGFIMCGVL 100
Query: 154 QIIVGF----SGL-WCHVVRFISPLSAVPLVALTGFGLYELGFPMLAKCIEIGLPEIVIL 208
+V F +G W V+ P + +VA+ G L + M G
Sbjct: 101 FCLVSFIVKKAGTGWLDVL--FPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPDSKT 158
Query: 209 VFLSQFMPHMMKGGRHIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDRAG 268
+ +S + G +F F I ++I + L+ D
Sbjct: 159 IIISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGI------------VDTTP 206
Query: 269 LIHGASWISPPIPFRWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVPPSV 328
+I+ A W + P + P F+ ++ A+ V E G + A +
Sbjct: 207 IIN-AHWFALPTLY---TPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLLRDPG 262
Query: 329 LSRGIGWQGVGILLSGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSILGK 388
L R + G+ ++SG FG+ ++ EN G++A+TRV S V+ +A F I S +GK
Sbjct: 263 LHRSMFANGLSTVISGFFGSTPNTTYG-ENIGVMAITRVYSTWVIGGAAIFAILLSCVGK 321
Query: 389 FGAVFASIPMPIVAALYCLLFSQVGSAGLSFL 420
A IP+P++ + LL+ +G++G+ L
Sbjct: 322 LAAAIQMIPLPVMGGVSLLLYGVIGASGIRVL 353
>YWDJ_BACSU (P39618) Putative purine permease ywdJ
Length = 460
Score = 75.1 bits (183), Expect = 4e-13
Identities = 99/430 (23%), Positives = 180/430 (41%), Gaps = 67/430 (15%)
Query: 55 MLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLIQTLFGTRLP------AVIGG 108
++ +++P A+ + + A LIQ+ FV GI +IQ L G RLP + G
Sbjct: 14 IIAAAIVVPVAVAQSFHLDHSDSARLIQSTFFVLGIAAVIQCLKGHRLPINESPAGLWWG 73
Query: 109 SFTFVPTTISIILASRYDDDIMHPREKFKRIMRGTQGALIVASSLQIIVGFSGLWCHVVR 168
+T + A+ D +RG QGAL+V++ ++ + + +
Sbjct: 74 VYTIYAGLTGTVFATYGD------------TLRGLQGALLVSAVCFFLLSVFKVIDRLAK 121
Query: 169 FISP-LSAVPLVALTGFGLYELGFPMLAKCIEIGLPE---------IVILVFLSQFMPHM 218
+P ++ V L+ L + +L P++ + IG + + ++V + F+ M
Sbjct: 122 LFTPVVTGVYLLLL----VMQLSQPIIKGILGIGYRQDGVDGLVFGLALVVIAAAFI--M 175
Query: 219 MKGGRHIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDRAGLIHGASWISP 278
F +++++ ++ WV + GA K E DR
Sbjct: 176 TNSNIMFFKQYSILLALFGGWV---LFAAAGAAKPIE-------MPDRL--------FQL 217
Query: 279 PIPFRWGAPTFDAGEAFAMMAASFVAQIESTGGF----IAVARFASATPVPPSVLSRGIG 334
P F +G P F++G + + + + IA+ +F+ G
Sbjct: 218 PSLFPFGTPLFNSGLIITSIFITILLIVNMLASMKVVDIAMKKFSKQPDGKHHERHAGFA 277
Query: 335 WQGVGILLSGIFGTGNGSSVSIEN-AGLLALTRVGSRRVVQISAGFMIFFSILGKFGAVF 393
LLSG+ TG + V I AG + T++ S++ + + +I S++ F F
Sbjct: 278 -ASFSHLLSGL--TGAIAPVPISGAAGFIETTKMPSKKPFMLGSILVIVISVIPFFMNTF 334
Query: 394 ASIPMPIVAALYCLLFSQVGSAGLSFLQFCNL---NSFRTKFIIGFSIFMGFSVPQYFKE 450
AS+P P+ A+ ++FS +G GL+F +F + S R + IIG S+ G + F
Sbjct: 335 ASLPSPVGFAVNFVVFSAMG--GLAFAEFDSYEKEESKRVRSIIGISLLTGVGI--MFVP 390
Query: 451 YTAIKQYGPV 460
TA+K PV
Sbjct: 391 ETALKGLHPV 400
>PYRP_BACCL (P41006) Uracil permease (Uracil transporter)
Length = 432
Score = 70.9 bits (172), Expect = 8e-12
Identities = 95/413 (23%), Positives = 170/413 (41%), Gaps = 49/413 (11%)
Query: 35 ITSPPPWPEAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLI 94
I P + I L QH M G T+L+P + G + A+L +G+ TL
Sbjct: 8 IQDRPTVGQWITLSLQHLFAMFGATILVP-----YLVGLDPSIALL------TSGLGTLA 56
Query: 95 QTLFGT-RLPAVIGGSFTFVPTTISIILASRYDDDIMHPREKFKRIMRGTQGALIVASSL 153
L ++PA +G SF ++ I+ A M G+ A +V +
Sbjct: 57 FLLITKWQVPAYLGSSFAYIAPIIAAKTAGGPG-----------AAMIGSFLAGLVYGVV 105
Query: 154 QIIVGFSGLWCHVVRFISPLSAVPLVALTGFGL--YELGFPMLAKCIEIGLPEI-VILVF 210
+I+ +G + V++ + P+ P++ + G GL +G M + L V LV
Sbjct: 106 ALIIKKAG-YRWVMKLLPPVVVGPVIIVIGLGLAGTAVGMAMNGPDGKYSLLHFSVALVT 164
Query: 211 LSQFMPHMMKGGRHIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDRAGLI 270
L+ + + R + + V+ +++ ++YA+ + K +
Sbjct: 165 LAATIVCSVL-ARGMLSLIPVLVGIVVGYLYALAVGLVDLSK-----------------V 206
Query: 271 HGASWISPP---IPFRWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVPPS 327
A W P IPF M+ + V E G + +++ +
Sbjct: 207 AAAKWFEWPDFLIPFADYPVRVTWEIVMLMVPVAIVTLSEHIGHQLVLSKVVGRDLIQKP 266
Query: 328 VLSRGIGWQGVGILLSGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSILG 387
L R I G ++S + G G + EN G+LA+TRV S V+ +A I F +G
Sbjct: 267 GLHRSILGDGTATMISALLG-GPPKTTYGENIGVLAITRVYSVYVLAGAAVIAIAFGFVG 325
Query: 388 KFGAVFASIPMPIVAALYCLLFSQVGSAGLSFLQFCNLNSFRTKFIIGFSIFM 440
K A+ +SIP P++ + LLF + S+GL L ++ +T+ ++ S+ +
Sbjct: 326 KITALISSIPTPVMGGVSILLFGIIASSGLRMLIDSRVDFGQTRNLVIASVIL 378
>YCDG_ECOLI (P75892) Putative purine permease ycdG
Length = 442
Score = 69.7 bits (169), Expect = 2e-11
Identities = 81/383 (21%), Positives = 152/383 (39%), Gaps = 48/383 (12%)
Query: 40 PWPEAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLIQTLF- 98
P+ + ++G QH + M G TVL+P + G + ++ ++GI TL+
Sbjct: 28 PFAQTAVMGVQHAVAMFGATVLMPILM------GLDPNLSIL-----MSGIGTLLFFFIT 76
Query: 99 GTRLPAVIGGSFTFVPTTISIILASRYDDDIMHPREKFKRIMRGTQGALIVASSLQIIVG 158
G R+P+ +G S FV +I A+ ++ ++P G +I + ++G
Sbjct: 77 GGRVPSYLGSSAAFVGV---VIAATGFNGQGINPNISI------ALGGIIACGLVYTVIG 127
Query: 159 FSGL-----WCHVVRFISPLSAVPLVALTGFGLYELGFPMLAKCIEIGLPEIVILVFLSQ 213
+ W + R + P+ +V G L P+ K + + + V
Sbjct: 128 LVVMKIGTRW--IERLMPPVVTGAVVMAIGLNLA----PIAVKSVSASAFDSWMAVMTVL 181
Query: 214 FMPHMMKGGRHIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDRAGLIHGA 273
+ + R + R ++ +I+ + ++T A T L+ A
Sbjct: 182 CIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFT----------LVSHA 231
Query: 274 SWISPPIPFRWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVPPSVLSRGI 333
+W P + P F+ + + + E+ G AVA P + R
Sbjct: 232 AWFGLP---HFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDP--YMGRAF 286
Query: 334 GWQGVGILLSGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSILGKFGAVF 393
G+ +LSG G G+G + EN G++A+T+V S V +A + KFGA+
Sbjct: 287 VGDGLATMLSGSVG-GSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALI 345
Query: 394 ASIPMPIVAALYCLLFSQVGSAG 416
+IP ++ ++F + AG
Sbjct: 346 HTIPAAVIGGASIVVFGLIAVAG 368
>UAPC_EMENI (P48777) Purine permease
Length = 580
Score = 69.7 bits (169), Expect = 2e-11
Identities = 115/507 (22%), Positives = 194/507 (37%), Gaps = 93/507 (18%)
Query: 44 AIMLGFQHYLVMLGTTVLIPTALVSQMGG--GNEEKAMLIQNHLFVAGINTLIQTL---- 97
A++LG QH L ML + P L G G +E L+ L V+G+ + +Q
Sbjct: 72 ALLLGLQHALAMLAGVITPPILLAGSSGANFGADESQYLVSTSLIVSGLLSAVQMFRLHV 131
Query: 98 ------FGTRLPAVIGGSFTFVPTTISIILASRYDDDIMHPREKFKRIM--RGTQGALIV 149
GT L +V+G SF + T + Y R+ +G GAL+
Sbjct: 132 YKTRYYVGTGLVSVVGTSFGTI-TVATGTFNQMYSTGYCPVDGSGNRLPCPKG-YGALLA 189
Query: 150 ASSLQII--VGFSGLWCHVVRFI-SPLSAVPLVALTGFGLY------------------- 187
S L + +G S + +++ + P+ P V L G L
Sbjct: 190 TSCLCSLLEIGLSFMSSRLLKALFPPIVTGPTVFLIGASLIGNAMKDWAGGSGTCSSNPG 249
Query: 188 --------ELGFPM---LAKCIEIGLPEIVILVFLSQFMPHMMKGGRHIFARFAVIFSVI 236
+ P+ A+ I +G ++ +F +MK AVI ++
Sbjct: 250 NGALCPSADAPHPLPWGSAEFIGLGFLVFATIILCERFGSPIMKS-------CAVIVGLL 302
Query: 237 IVWVYAIILTGCGAYKNAEHETQDTCRTDRAGLIHGASWISPPIPFRWGAP---TFDAGE 293
V I+ CG + DR+G+ +P F W T A
Sbjct: 303 ---VGCIVAAACGYF-------------DRSGID-----AAPVASFIWVKTFPLTIYAPL 341
Query: 294 AFAMMAASFVAQIESTGGFIA---VARFASATPVPPSVLSRGIGWQGVGILLSGIFGTGN 350
++A V +ES G A V+R S + G+ G+ LL+G+ T
Sbjct: 342 ILPLLAVYMVIMMESIGDITATCDVSRLQVEGATFDSRIQGGVLGNGITCLLAGLC-TIT 400
Query: 351 GSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSILGKFGAVFASIPMPIVAALYCLLFS 410
SV +N G++ALT +R+ F++ I KF A +IP ++ + LFS
Sbjct: 401 PMSVFAQNNGVIALTPCANRKAGYCCCFFLVVMGIFAKFAAALVAIPSSVLGGMTTFLFS 460
Query: 411 QVGSAGLSFLQFCNLN-SFRTKFIIGFSIFMGFS---VPQYFKEYTAIKQYGPVHTNARW 466
V +G+ + C+++ + R +FI+ S +G + VP +F + Y +
Sbjct: 461 SVAISGVRIM--CSVDWTRRNRFILTASFAVGMAATLVPDWFSYFFT---YSGDNHALEG 515
Query: 467 FNDMINVPFSSGAFVAGILALFFDVTL 493
+ + ++G V G L L ++ L
Sbjct: 516 LLQAVELVMANGFAVTGFLGLLLNLIL 542
>URAA_PASMU (Q9CPL9) Probable uracil permease (Uracil transporter)
Length = 417
Score = 58.2 bits (139), Expect = 5e-08
Identities = 85/428 (19%), Positives = 158/428 (36%), Gaps = 73/428 (17%)
Query: 47 LGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLI-QTLFGTRLPAV 105
+G Q V G VL+P + G N A+L AGI TL+ Q G ++P
Sbjct: 20 VGLQMLFVAFGALVLVPL-----ITGLNANTALL------TAGIGTLLFQLCTGRQVPIF 68
Query: 106 IGGSFTFV-PTTISIILASRYDDDIMHPREKFKRIMRGTQGALIVASSLQIIVGFSGLWC 164
+ SF F+ P + M G +V +L +V G
Sbjct: 69 LASSFAFIAPIQYGVTTWG------------IATTMGGLVFTGLVYFALSTLVKIKGAGA 116
Query: 165 HVVRFISPLSAVPLVALTGFGLYELGFPM-LAK--------CIEIGLPEIVILVFLSQFM 215
+ + P+ P++ + G GL + M L K + + + ++ + ++ F
Sbjct: 117 -LQKVFPPVVVGPVIIIIGMGLAPVAVDMALGKNSTYQYNDAVFVSMATLLTTLGVAVFA 175
Query: 216 PHMMKGGRHIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDRAGLIH---- 271
MMK ++F +++ ++ + L GLI+
Sbjct: 176 KGMMK-------LIPIMFGIVVGYILCLFL----------------------GLINFQPV 206
Query: 272 -GASWISPPIPFRWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVPPSVLS 330
A W S P P F ++ + +E GG +A++ + L
Sbjct: 207 IDAPWFSVP---EITTPEFKLEAILYLLPIAIAPAVEHVGGIMAISSVTGKDFLQKPGLH 263
Query: 331 RGIGWQGVGILLSGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSILGKFG 390
R + G+ + G G ++ E G + LTR + +++ +A + I S GK G
Sbjct: 264 RTLLGDGIATSAASFLG-GPPNTTYAEVTGAVMLTRNFNPKIMTWAAVWAIAISFCGKVG 322
Query: 391 AVFASIPMPIVAALYCLLFSQVGSAGLSFLQFCNLNSFRTKFIIGFSIFMGFSVPQYFKE 450
A ++IP ++ + L+F + G+S L ++ + + S+ M F + F
Sbjct: 323 AFLSTIPTIVMGGIMMLVFGSIAVVGMSTLIRGKVDVTEARNLCIISVVMTFGIGGMFVN 382
Query: 451 YTAIKQYG 458
+ + G
Sbjct: 383 FGEVSLKG 390
>URAA_HAEIN (P45117) Probable uracil permease (Uracil transporter)
Length = 414
Score = 57.4 bits (137), Expect = 9e-08
Identities = 93/469 (19%), Positives = 173/469 (36%), Gaps = 93/469 (19%)
Query: 47 LGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLI-QTLFGTRLPAV 105
+G Q V G VL+P + G + A+L AG+ TL+ Q G ++P
Sbjct: 21 VGLQMLFVAFGALVLVPL-----ITGLDSNTALL------TAGVGTLLFQFCTGKQVPIF 69
Query: 106 IGGSFTFV-PTTISIILASRYDDDIMHPREKFKRIMRGTQGALIVASSLQIIVGFSGLWC 164
+ SF F+ P + M G +V +L +V G
Sbjct: 70 LASSFAFIAPIQYGVQTWG------------IATTMGGLAFTGLVYFALSTLVKLRGAEA 117
Query: 165 HVVRFISPLSAVPLVALTGFGLYELGFPM-LAK--------CIEIGLPEIVILVFLSQFM 215
+ RF P+ P++ + G GL + M L K + + + ++ + ++ F
Sbjct: 118 -LQRFFPPVVVGPVIIIIGMGLAPIAVDMSLGKNSAYAYNDAVLVSMVTLLTTLSVAVFA 176
Query: 216 PHMMKGGRHIFARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDRAGLIH---- 271
+MK ++F + ++ + L GLI+
Sbjct: 177 KGLMK-------LIPIMFGITAGYILCLFL----------------------GLINFQPV 207
Query: 272 -GASWISPPIPFRWGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASATPVPPSVLS 330
A W S P + P F+ M+ + +E GG +A++ + L
Sbjct: 208 IDAPWFSLP---KLTTPEFNLEAILYMLPIAIAPAVEHVGGIMAISSVTGKDFLKKPGLH 264
Query: 331 RGIGWQGVGILLSGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIFFSILGKFG 390
R + G+ + + G G ++ E G + LTR + ++ +A + I S GK G
Sbjct: 265 RTLLGDGIATAAASLVG-GPPNTTYAEVTGAVMLTRNFNPNIMTWAAVWAIAISFCGKVG 323
Query: 391 AVFASIPMPIVAALYCLLFSQVGSAGLSFLQFCNLNSFRTKFIIGFSIFMGFSVPQYFKE 450
A ++IP ++ + L+F + G+S L ++ + + S+ M F +
Sbjct: 324 AFLSTIPTIVMGGIMMLVFGSIAVVGMSTLIRGKVDVTEARNLCIISVVMTFGI------ 377
Query: 451 YTAIKQYGPVHTNARWFNDMINVPFSSGAFVAGILALFFDVTLHKSDNQ 499
F D+ NV G + I+A+ ++ L K+ N+
Sbjct: 378 -------------GNMFVDVGNVSL-KGISLCAIVAIILNLVLPKAKNE 412
>UAPA_EMENI (Q07307) Uric acid-xanthine permease (UAPA transporter)
Length = 615
Score = 56.2 bits (134), Expect = 2e-07
Identities = 94/444 (21%), Positives = 171/444 (38%), Gaps = 60/444 (13%)
Query: 44 AIMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLIQTL------ 97
A +LG QH L ML V P + S + ++ + L+ L V G+ +++Q
Sbjct: 120 AFILGLQHALAMLAGVVTPPLIISSSLSLPSDLQQYLVSTSLIVCGLLSMVQITRFHIYK 179
Query: 98 ----FGTRLPAVIGGSFTFVPTTISIILASRYDDDIMHPREKFKRI-MRGTQGALIVASS 152
G+ + +V+G SF+ + + S Y + E R+ G LI S+
Sbjct: 180 TPYYIGSGVLSVMGVSFSII-SVASGPFNQMYSNGFCQLDEAGNRLPCPEAYGRLIGTSA 238
Query: 153 ----LQIIVGFSGLWCHVVRFISPLSAVPLVALTGFGLYELGFPMLA---KCIEIGL--- 202
++I++ F + + P+ P V L G L GF A C++ G+
Sbjct: 239 CCALVEILLAFVPPKV-IQKIFPPIVTGPTVMLIGISLIGTGFKDWAGGSACMDDGMLCP 297
Query: 203 ------------PEIV---ILVFLSQFMPHMMKGGRHIFARFAVIFSVIIVWVYAIILTG 247
PE + LVF+S + G I +V+ ++ V I+
Sbjct: 298 SATAPRPLPWGSPEFIGLGFLVFVSIILCERF--GAPIMKSCSVVIGLL---VGCIVAAA 352
Query: 248 CGAYKNAEHETQDTCRTDRAGLIHGASWISPPIPFRWGAPTFDAGEAFAMMAASFVAQIE 307
CG + +A+ + A I W+ +G F + A + +
Sbjct: 353 CGYFSHADIDAAPA-----ASFI----WVKTFPLSVYGPMVLPIIAVFIICACECIGDVT 403
Query: 308 STGGFIAVARFASATPVPPSVLSRGIGWQGVGILLSGIFGTGNGSSVSIENAGLLALTRV 367
+T V+R S + + G+ +++ + T + +N G++ALTR
Sbjct: 404 AT---CDVSRLEVRGGTFESRIQGAVLADGINSVVAAL-ATMTPMTTFAQNNGVIALTRC 459
Query: 368 GSRRVVQISAGFMIFFSILGKFGAVFASIPMPIVAALYCLLFSQVGSAGLSFLQFCNLNS 427
+R +I I KF A +IP ++ + LF+ V +G + +
Sbjct: 460 ANRWAGYCCCLILIVAGIFAKFAAAIVAIPNSVMGGMKTFLFASVVISGQAIVAKAPFTR 519
Query: 428 FRTKFIIGFSIFMGFS---VPQYF 448
R +FI+ S+ +G+ VP +F
Sbjct: 520 -RNRFILTASMALGYGATLVPTWF 542
>PYRP_BACSU (P39766) Uracil permease (Uracil transporter)
Length = 434
Score = 55.5 bits (132), Expect = 4e-07
Identities = 87/398 (21%), Positives = 151/398 (37%), Gaps = 59/398 (14%)
Query: 35 ITSPPPWPEAIMLGFQHYLVMLGTTVLIPTALVSQMGGGNEEKAMLIQNHLFVAGINTLI 94
+ +P W + QH M G+T+L+P + M L +GI TL
Sbjct: 13 VPTPFSW---VSFSLQHLFAMFGSTILVPKLV-----------GMSPAVALVTSGIGTLA 58
Query: 95 QTLFGT-RLPAVIGGSFTFVPTTISIILASRYDDDIMHPREKFKRIMRGTQGALIVASSL 153
L ++PA +G SF F+ I + + G A++ A
Sbjct: 59 YLLITKGQIPAYLGSSFAFISPIILV------------------KATGGPGAAMVGAFLA 100
Query: 154 QIIVGFSGLWCH------VVRFISPLSAVPLVALTGFGLYELGFPMLAKCIEIGLPEIVI 207
++ G L +++ + P+ P++ + G GL M A + E+V
Sbjct: 101 GLVYGLIALLIRQLGTGWLMKILPPVVVGPVIIVIGLGLASTAVNM-AMYADPNASELVY 159
Query: 208 LVFLSQFMPHMMKGGRHI-FARFAVIFSVIIVWVYAIILTGCGAYKNAEHETQDTCRTDR 266
+ H G + IF + + +++ G Y A TQ
Sbjct: 160 S------LKHFSVAGVTLAITIICAIFLRGFLSLIPVLIGIIGGYLFAL--TQGIVNFQP 211
Query: 267 AGLIHGASWISPP---IPFR-WGAPTFDAGEAFAMMAASFVAQIESTGGFIAVARFASAT 322
+ A W + P IPF+ + A + + S ++Q +S
Sbjct: 212 ---VLDAKWFAVPEFIIPFKDYHRQLRSASQPQWFL--SHLSQCQSISATNGAESKVVGQ 266
Query: 323 PVPPSVLSRGIGWQGVGILLSGIFGTGNGSSVSIENAGLLALTRVGSRRVVQISAGFMIF 382
+ L R I V +L+ + G G ++ EN G+LA+TRV S V+ +A +
Sbjct: 267 DFIKAGLHRSIMGDSVATILASLIG-GPPTTTYGENIGVLAITRVFSVFVIGGAAVIALC 325
Query: 383 FSILGKFGAVFASIPMPIVAALYCLLFSQVGSAGLSFL 420
F +GK A+ +S+P ++ + LLF + S+GL L
Sbjct: 326 FGFIGKISALISSVPSAVMGGVSFLLFGIIASSGLRML 363
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.327 0.142 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,213,966
Number of Sequences: 164201
Number of extensions: 2877791
Number of successful extensions: 11243
Number of sequences better than 10.0: 40
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 11144
Number of HSP's gapped (non-prelim): 56
length of query: 538
length of database: 59,974,054
effective HSP length: 115
effective length of query: 423
effective length of database: 41,090,939
effective search space: 17381467197
effective search space used: 17381467197
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 68 (30.8 bits)
Medicago: description of AC126785.11