BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC124964.6 - phase: 0 
         (387 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

MMK1_MEDSA (Q07176) Mitogen-activated protein kinase homolog MMK...   788  0.0
MAPK_PEA (Q06060) Mitogen-activated protein kinase homolog D5 (E...   749  0.0
NTF4_TOBAC (Q40532) Mitogen-activated protein kinase homolog NTF...   723  0.0
MPK6_ARATH (Q39026) Mitogen-activated protein kinase homolog 6 (...   706  0.0
MPK3_ARATH (Q39023) Mitogen-activated protein kinase homolog 3 (...   581  e-165
MPK4_ARATH (Q39024) Mitogen-activated protein kinase homolog 4 (...   556  e-158
MMK2_MEDSA (Q40353) Mitogen-activated protein kinase homolog MMK...   549  e-156
NTF6_TOBAC (Q40531) Mitogen-activated protein kinase homolog NTF...   542  e-154
MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (...   536  e-152
MAPK_PETHY (Q40884) Mitogen-activated protein kinase homolog 1 (...   425  e-118
ERK1_DICDI (P42525) Extracellular signal-regulated kinase 1 (EC ...   425  e-118
NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF...   424  e-118
MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (...   415  e-116
MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (...   413  e-115
MPK2_ARATH (Q39022) Mitogen-activated protein kinase homolog 2 (...   409  e-114
MK01_BOVIN (P46196) Mitogen-activated protein kinase 1 (EC 2.7.1...   365  e-100
MK01_HUMAN (P28482) Mitogen-activated protein kinase 1 (EC 2.7.1...   364  e-100
MK01_RAT (P63086) Mitogen-activated protein kinase 1 (EC 2.7.1.3...   364  e-100
MK01_MOUSE (P63085) Mitogen-activated protein kinase 1 (EC 2.7.1...   364  e-100
MK01_XENLA (P26696) Mitogen-activated protein kinase 1 (EC 2.7.1...   363  e-100

>MMK1_MEDSA (Q07176) Mitogen-activated protein kinase homolog MMK1
           (EC 2.7.1.37) (MAP kinase MSK7) (MAP kinase ERK1)
          Length = 387

 Score =  788 bits (2036), Expect = 0.0
 Identities = 385/387 (99%), Positives = 385/387 (99%)

Query: 1   MEGGGAPPADTVMSDAAPAPPQMGIENIPATLSHGGRFIQYNIFGNIFEVTAKYKPPIMP 60
           MEGGGAPPADTVMSDAAPAPPQMGIENIPA LSHGGRFIQYNIFGNIFEVTAKYKPPIMP
Sbjct: 1   MEGGGAPPADTVMSDAAPAPPQMGIENIPAVLSHGGRFIQYNIFGNIFEVTAKYKPPIMP 60

Query: 61  IGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDI 120
           IGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDI
Sbjct: 61  IGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDI 120

Query: 121 VPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHR 180
           VPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHR
Sbjct: 121 VPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHR 180

Query: 181 DLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVW 240
           DLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVW
Sbjct: 181 DLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVW 240

Query: 241 SVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDLGFLNENAKRYIRQLPPYRRQ 300
           SVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDLGFLNENAKRYIRQLPPYRRQ
Sbjct: 241 SVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDLGFLNENAKRYIRQLPPYRRQ 300

Query: 301 SFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHPYLTSLHDISDEPVCMTPFSFDF 360
           SFQEKFP VHPEAIDLVEKMLTFDPRKRITVEDALAHPYLTSLHDISDEPVCMTPFSFDF
Sbjct: 301 SFQEKFPHVHPEAIDLVEKMLTFDPRKRITVEDALAHPYLTSLHDISDEPVCMTPFSFDF 360

Query: 361 EQHALTEEQMKELIYREALAFNPEYQQ 387
           EQHALTEEQMKELIYREALAFNPEYQQ
Sbjct: 361 EQHALTEEQMKELIYREALAFNPEYQQ 387


>MAPK_PEA (Q06060) Mitogen-activated protein kinase homolog D5 (EC
           2.7.1.37)
          Length = 394

 Score =  749 bits (1934), Expect = 0.0
 Identities = 370/391 (94%), Positives = 375/391 (95%), Gaps = 6/391 (1%)

Query: 3   GGGAPPADTVMSDAAPAPPQ------MGIENIPATLSHGGRFIQYNIFGNIFEVTAKYKP 56
           GGGAP AD VM DAAP   +      MGIENIPATLSHGGRFIQYNIFGNIFEVTAKY+P
Sbjct: 4   GGGAPAADAVMEDAAPQQQEPQQQAAMGIENIPATLSHGGRFIQYNIFGNIFEVTAKYRP 63

Query: 57  PIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVA 116
           PIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKL+RHMDHENVVA
Sbjct: 64  PIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLVRHMDHENVVA 123

Query: 117 IRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSAN 176
           IRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSAN
Sbjct: 124 IRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSAN 183

Query: 177 VLHRDLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAA 236
           VLHRDLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAA
Sbjct: 184 VLHRDLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAA 243

Query: 237 IDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDLGFLNENAKRYIRQLPP 296
           IDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSE DLGFLNENAKRYIRQLP 
Sbjct: 244 IDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEADLGFLNENAKRYIRQLPL 303

Query: 297 YRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHPYLTSLHDISDEPVCMTPF 356
           YRRQSFQEKFP VHPEAIDLVEKMLTFDPR+RITVE+ALAHPYLTSLHDISDEPVC TPF
Sbjct: 304 YRRQSFQEKFPHVHPEAIDLVEKMLTFDPRQRITVENALAHPYLTSLHDISDEPVCTTPF 363

Query: 357 SFDFEQHALTEEQMKELIYREALAFNPEYQQ 387
           SFDFEQHALTEEQMKELIYREALAFNPEYQQ
Sbjct: 364 SFDFEQHALTEEQMKELIYREALAFNPEYQQ 394


>NTF4_TOBAC (Q40532) Mitogen-activated protein kinase homolog NTF4
           (EC 2.7.1.37) (P45)
          Length = 393

 Score =  723 bits (1866), Expect = 0.0
 Identities = 358/389 (92%), Positives = 367/389 (94%), Gaps = 6/389 (1%)

Query: 4   GGAPPADTVMSDAA---PAPPQM---GIENIPATLSHGGRFIQYNIFGNIFEVTAKYKPP 57
           G A   DTVMSDAA   PAPP     GI+NIPATLSHGGRFIQYNIFGNIFEVTAKYKPP
Sbjct: 3   GPAHQTDTVMSDAAGQQPAPPSQPVAGIDNIPATLSHGGRFIQYNIFGNIFEVTAKYKPP 62

Query: 58  IMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVAI 117
           IMPIGKGAYGIVCSA NSETNEHVA+KKIANAFDNKIDAKRTLREIKLLRHMDHEN+VAI
Sbjct: 63  IMPIGKGAYGIVCSALNSETNEHVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAI 122

Query: 118 RDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANV 177
           RDI+PPPQRE FNDVYIAYELMDTDLHQIIRSNQ LSEEHCQYFLYQILRGLKYIHSANV
Sbjct: 123 RDIIPPPQREAFNDVYIAYELMDTDLHQIIRSNQGLSEEHCQYFLYQILRGLKYIHSANV 182

Query: 178 LHRDLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAAI 237
           LHRDLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAAI
Sbjct: 183 LHRDLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAAI 242

Query: 238 DVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDLGFLNENAKRYIRQLPPY 297
           DVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSE ++ FLNENAKRYIRQLP Y
Sbjct: 243 DVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEAEMEFLNENAKRYIRQLPLY 302

Query: 298 RRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHPYLTSLHDISDEPVCMTPFS 357
           RRQSF EKFP V+P AIDLVEKMLTFDPR+RITVEDALAHPYLTSLHDISDEPVCMTPF+
Sbjct: 303 RRQSFVEKFPHVNPAAIDLVEKMLTFDPRRRITVEDALAHPYLTSLHDISDEPVCMTPFN 362

Query: 358 FDFEQHALTEEQMKELIYREALAFNPEYQ 386
           FDFEQHALTEEQMKELIYRE LAFNPEYQ
Sbjct: 363 FDFEQHALTEEQMKELIYREGLAFNPEYQ 391


>MPK6_ARATH (Q39026) Mitogen-activated protein kinase homolog 6 (EC
           2.7.1.37) (MAP kinase 6) (AtMPK6)
          Length = 395

 Score =  706 bits (1823), Expect = 0.0
 Identities = 349/395 (88%), Positives = 364/395 (91%), Gaps = 8/395 (2%)

Query: 1   MEGG-GAPPADTVMSDA-------APAPPQMGIENIPATLSHGGRFIQYNIFGNIFEVTA 52
           M+GG G P ADT M++A       AP+P   GIENIPATLSHGGRFIQYNIFGNIFEVTA
Sbjct: 1   MDGGSGQPAADTEMTEAPGGFPAAAPSPQMPGIENIPATLSHGGRFIQYNIFGNIFEVTA 60

Query: 53  KYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHE 112
           KYKPPIMPIGKGAYGIVCSA NSETNE VA+KKIANAFDNKIDAKRTLREIKLLRHMDHE
Sbjct: 61  KYKPPIMPIGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLREIKLLRHMDHE 120

Query: 113 NVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYI 172
           N+VAIRDI+PPP R  FNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYI
Sbjct: 121 NIVAIRDIIPPPLRNAFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYI 180

Query: 173 HSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSD 232
           HSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSE+DFMTEYVVTRWYRAPELLLNSSD
Sbjct: 181 HSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSESDFMTEYVVTRWYRAPELLLNSSD 240

Query: 233 YTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDLGFLNENAKRYIR 292
           YTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSE++L FLNENAKRYIR
Sbjct: 241 YTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEEELEFLNENAKRYIR 300

Query: 293 QLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHPYLTSLHDISDEPVC 352
           QLPPY RQS  +KFP VHP AIDL+EKMLTFDPR+RITV DALAHPYL SLHDISDEP C
Sbjct: 301 QLPPYPRQSITDKFPTVHPLAIDLIEKMLTFDPRRRITVLDALAHPYLNSLHDISDEPEC 360

Query: 353 MTPFSFDFEQHALTEEQMKELIYREALAFNPEYQQ 387
             PF+FDFE HAL+EEQMKELIYREALAFNPEYQQ
Sbjct: 361 TIPFNFDFENHALSEEQMKELIYREALAFNPEYQQ 395


>MPK3_ARATH (Q39023) Mitogen-activated protein kinase homolog 3 (EC
           2.7.1.37) (MAP kinase 3) (AtMPK3)
          Length = 370

 Score =  581 bits (1497), Expect = e-165
 Identities = 275/360 (76%), Positives = 319/360 (88%), Gaps = 1/360 (0%)

Query: 27  NIPATLSHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKI 86
           + PA  +HGG+FI Y+IFG++FE+T+KY+PPI+PIG+GAYGIVCS  ++ETNE VA+KKI
Sbjct: 10  DFPAVETHGGQFISYDIFGSLFEITSKYRPPIIPIGRGAYGIVCSVLDTETNELVAMKKI 69

Query: 87  ANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQI 146
           ANAFDN +DAKRTLREIKLLRH+DHEN++AIRD+VPPP R  F+DVYI+ ELMDTDLHQI
Sbjct: 70  ANAFDNHMDAKRTLREIKLLRHLDHENIIAIRDVVPPPLRRQFSDVYISTELMDTDLHQI 129

Query: 147 IRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVT 206
           IRSNQ+LSEEHCQYFLYQ+LRGLKYIHSAN++HRDLKPSNLLLNANCDLKICDFGLAR T
Sbjct: 130 IRSNQSLSEEHCQYFLYQLLRGLKYIHSANIIHRDLKPSNLLLNANCDLKICDFGLARPT 189

Query: 207 SETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLR 266
           SE DFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELM+RKPLFPG+DHVHQ+R
Sbjct: 190 SENDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMNRKPLFPGKDHVHQMR 249

Query: 267 LLMELIGTPSEDDLGFL-NENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDP 325
           LL EL+GTP+E DLGF  NE+AKRYIRQLP + RQ   + F  V+P AIDLV++MLTFDP
Sbjct: 250 LLTELLGTPTESDLGFTHNEDAKRYIRQLPNFPRQPLAKLFSHVNPMAIDLVDRMLTFDP 309

Query: 326 RKRITVEDALAHPYLTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPEY 385
            +RITVE AL H YL  LHD +DEP+C  PFSF+FEQ  L EEQ+KE+IY+EA+A NP Y
Sbjct: 310 NRRITVEQALNHQYLAKLHDPNDEPICQKPFSFEFEQQPLDEEQIKEMIYQEAIALNPTY 369


>MPK4_ARATH (Q39024) Mitogen-activated protein kinase homolog 4 (EC
           2.7.1.37) (MAP kinase 4) (AtMPK4)
          Length = 376

 Score =  556 bits (1432), Expect = e-158
 Identities = 257/353 (72%), Positives = 308/353 (86%), Gaps = 1/353 (0%)

Query: 33  SHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDN 92
           +HGG ++QYN++GN+FEV+ KY PP+ PIG+GAYGIVC+A NSET E VA+KKI NAFDN
Sbjct: 21  THGGSYVQYNVYGNLFEVSRKYVPPLRPIGRGAYGIVCAATNSETGEEVAIKKIGNAFDN 80

Query: 93  KIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQA 152
            IDAKRTLREIKLL+HMDHENV+A++DI+ PPQRE FNDVYI YELMDTDLHQIIRSNQ 
Sbjct: 81  IIDAKRTLREIKLLKHMDHENVIAVKDIIKPPQRENFNDVYIVYELMDTDLHQIIRSNQP 140

Query: 153 LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSETDFM 212
           L+++HC++FLYQ+LRGLKY+HSANVLHRDLKPSNLLLNANCDLK+ DFGLAR  SETDFM
Sbjct: 141 LTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKLGDFGLARTKSETDFM 200

Query: 213 TEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELI 272
           TEYVVTRWYRAPELLLN S+YTAAID+WSVGCI  E M R+PLFPG+D+VHQLRL+ ELI
Sbjct: 201 TEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLITELI 260

Query: 273 GTPSEDDLGFL-NENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITV 331
           G+P +  LGFL ++NA+RY+RQLP Y RQ+F  +FP +   A+DL+EKML FDP +RITV
Sbjct: 261 GSPDDSSLGFLRSDNARRYVRQLPQYPRQNFAARFPNMSAGAVDLLEKMLVFDPSRRITV 320

Query: 332 EDALAHPYLTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPE 384
           ++AL HPYL  LHDI++EPVC+ PF+FDFEQ  LTEE +KELIYRE + FNP+
Sbjct: 321 DEALCHPYLAPLHDINEEPVCVRPFNFDFEQPTLTEENIKELIYRETVKFNPQ 373


>MMK2_MEDSA (Q40353) Mitogen-activated protein kinase homolog MMK2
           (EC 2.7.1.37)
          Length = 371

 Score =  549 bits (1415), Expect = e-156
 Identities = 256/359 (71%), Positives = 310/359 (86%), Gaps = 1/359 (0%)

Query: 27  NIPATLSHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKI 86
           NI    +HGGR++QYNI+GN+FEV+ KY PPI  +G+GAYGIVC+A N+ET E VA+KKI
Sbjct: 9   NIRGVPTHGGRYLQYNIYGNLFEVSRKYVPPIRSVGRGAYGIVCAAVNAETREEVAIKKI 68

Query: 87  ANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQI 146
            NAFDN+IDAKRTLREIKLLRHMDHENV++I+DI+ PPQ+E FN VYI  ELMDTDLHQI
Sbjct: 69  GNAFDNRIDAKRTLREIKLLRHMDHENVMSIKDIIRPPQKENFNHVYIVSELMDTDLHQI 128

Query: 147 IRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVT 206
           IRSNQ ++++HC+YF+YQ+LRGLKY+HSANVLHRDLKPSNLLLNANCDLKI DFGLAR T
Sbjct: 129 IRSNQPMTDDHCRYFVYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLARTT 188

Query: 207 SETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLR 266
           SETDFMTEYVVTRWYRAPELLLN SDYTAAID+WSVGCI  E++ R+PLFPGRD+VHQLR
Sbjct: 189 SETDFMTEYVVTRWYRAPELLLNCSDYTAAIDIWSVGCILGEIVTRQPLFPGRDYVHQLR 248

Query: 267 LLMELIGTPSEDDLGFL-NENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDP 325
           L+ ELIG+P +  LGFL +ENA+RY+RQLP Y +Q+F  +FP + P A+DL+EKML FDP
Sbjct: 249 LVTELIGSPDDASLGFLRSENARRYVRQLPQYPKQNFSARFPNMSPGAVDLLEKMLIFDP 308

Query: 326 RKRITVEDALAHPYLTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPE 384
            KRI V++AL HPY+  LHDI++EPVC  PFSFDFE+   TEE +KELI++E++ FNP+
Sbjct: 309 SKRIKVDEALCHPYMAPLHDINEEPVCARPFSFDFEEPMFTEEDIKELIWKESVRFNPD 367


>NTF6_TOBAC (Q40531) Mitogen-activated protein kinase homolog NTF6
           (EC 2.7.1.37) (P43)
          Length = 371

 Score =  542 bits (1397), Expect = e-154
 Identities = 253/363 (69%), Positives = 310/363 (84%), Gaps = 4/363 (1%)

Query: 22  QMGIENIPATLSHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHV 81
           ++ I+ IP   +H G++++YN+ GN FEVT+KY PPI P+G+GAYG+VC A NSET E V
Sbjct: 8   KLEIKGIP---THEGKYVEYNVLGNFFEVTSKYIPPIQPVGRGAYGMVCCATNSETKEEV 64

Query: 82  AVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDT 141
           A+KKI NAF+N+IDAKRTLREIKLL HMDHEN++ I+DIV PP RE FNDVYI YELMDT
Sbjct: 65  AIKKIGNAFENRIDAKRTLREIKLLSHMDHENIIKIKDIVRPPDREEFNDVYIVYELMDT 124

Query: 142 DLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFG 201
           DLHQIIRS+QAL+++HCQYFLYQ+LRGLKY+HSANVLHRDLKPSNLLLNANCDLKICDFG
Sbjct: 125 DLHQIIRSSQALTDDHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKICDFG 184

Query: 202 LARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDH 261
           LAR TSE DFMTEYVVTRWYRAPELLLN ++YTAAID+WSVGCI MEL+ R+PLFPGRD+
Sbjct: 185 LARTTSEADFMTEYVVTRWYRAPELLLNCTEYTAAIDIWSVGCILMELIKREPLFPGRDY 244

Query: 262 VHQLRLLMELIGTPSEDDLGFL-NENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKM 320
             QL L++ L+G+P + DLGFL ++NA++Y++ LP   R  F +KFP V P A+DL E+M
Sbjct: 245 AQQLGLIIALLGSPEDSDLGFLRSDNARKYVKHLPRVPRHPFSQKFPDVSPLALDLAERM 304

Query: 321 LTFDPRKRITVEDALAHPYLTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALA 380
           L FDP KRITVEDAL HP+L SLH+I++EPVC +PF+FDFEQ +L+E+ +KELI+ EAL 
Sbjct: 305 LVFDPAKRITVEDALNHPFLISLHEINEEPVCDSPFNFDFEQASLSEDDIKELIWNEALK 364

Query: 381 FNP 383
           F+P
Sbjct: 365 FDP 367


>MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (EC
           2.7.1.37) (MAP kinase 5) (AtMPK5)
          Length = 376

 Score =  536 bits (1381), Expect = e-152
 Identities = 251/372 (67%), Positives = 314/372 (83%), Gaps = 1/372 (0%)

Query: 13  MSDAAPAPPQMGIENIPATLSHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSA 72
           M+    +   +G  NI   L HGGR+ QYN++GN+FEV+ KY PPI PIG+GAYG VC+A
Sbjct: 1   MAKEIESATDLGDTNIKGVLVHGGRYFQYNVYGNLFEVSNKYVPPIRPIGRGAYGFVCAA 60

Query: 73  HNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDV 132
            +SET+E +A+KKI  AFDNK+DAKRTLREIKLLRH++HENVV I+DI+ PP++E F DV
Sbjct: 61  VDSETHEEIAIKKIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDV 120

Query: 133 YIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNAN 192
           YI +ELMDTDLHQIIRSNQ+L+++HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLN+N
Sbjct: 121 YIVFELMDTDLHQIIRSNQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSN 180

Query: 193 CDLKICDFGLARVTSETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDR 252
           CDLKI DFGLAR TSET++MTEYVVTRWYRAPELLLNSS+YT+AIDVWSVGCIF E+M R
Sbjct: 181 CDLKITDFGLARTTSETEYMTEYVVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTR 240

Query: 253 KPLFPGRDHVHQLRLLMELIGTPSEDDLGFL-NENAKRYIRQLPPYRRQSFQEKFPQVHP 311
           +PLFPG+D+VHQL+L+ ELIG+P    L FL + NA++Y+++LP + RQ+F  +FP ++ 
Sbjct: 241 EPLFPGKDYVHQLKLITELIGSPDGASLEFLRSANARKYVKELPKFPRQNFSARFPSMNS 300

Query: 312 EAIDLVEKMLTFDPRKRITVEDALAHPYLTSLHDISDEPVCMTPFSFDFEQHALTEEQMK 371
            AIDL+EKML FDP KRITVE+AL +PYL++LHD++DEPVC   FSF FE  + TEE++K
Sbjct: 301 TAIDLLEKMLVFDPVKRITVEEALCYPYLSALHDLNDEPVCSNHFSFHFEDPSSTEEEIK 360

Query: 372 ELIYREALAFNP 383
           EL++ E++ FNP
Sbjct: 361 ELVWLESVKFNP 372


>MAPK_PETHY (Q40884) Mitogen-activated protein kinase homolog 1 (EC
           2.7.1.37) (PMEK1)
          Length = 384

 Score =  425 bits (1092), Expect = e-118
 Identities = 201/346 (58%), Positives = 271/346 (78%), Gaps = 4/346 (1%)

Query: 41  YNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTL 100
           Y+++ ++FE+  KY P I PIG+GAYGIVCS+ N ETNE VA+KKI NAF+N+IDA RTL
Sbjct: 19  YSMWQSLFEIDTKYVP-IKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTL 77

Query: 101 REIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQY 160
           RE+KLLRH+ HENV+A++D++ P QR  F DVY+ YELMDTDLHQII+S+Q LS +HCQY
Sbjct: 78  RELKLLRHLRHENVIALKDVMMPIQRRSFKDVYLVYELMDTDLHQIIKSSQTLSNDHCQY 137

Query: 161 FLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSETD-FMTEYVVTR 219
           FL+Q+LRGLKY+HSAN+LHRDLKP NLL+NANCDLKICDFGLAR +S  D FMTEYVVTR
Sbjct: 138 FLFQLLRGLKYLHSANILHRDLKPGNLLINANCDLKICDFGLARTSSGKDQFMTEYVVTR 197

Query: 220 WYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDD 279
           WYRAPELLL   +Y  +IDVWSVGCIF +++ RKP+FPG + ++QL+L++ ++G+  E+D
Sbjct: 198 WYRAPELLLCCDNYGTSIDVWSVGCIFADVLGRKPVFPGTECLNQLKLIINILGSQREED 257

Query: 280 LGFL-NENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHP 338
           + F+ N  A++YI+ LP      F   +P  HP AIDL+++ML FDP KRI+V +AL HP
Sbjct: 258 IEFIDNPKARKYIKSLPYSPGTPFSRLYPNAHPLAIDLLQRMLVFDPSKRISVMEALQHP 317

Query: 339 YLTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPE 384
           Y++ L+D + +P    P + D ++  L EE ++E+++ E L ++PE
Sbjct: 318 YMSPLYDPNTDPPAQVPINLDIDED-LVEETIREMMWEEILHYHPE 362


>ERK1_DICDI (P42525) Extracellular signal-regulated kinase 1 (EC
           2.7.1.37) (ERK1) (MAP kinase 1)
          Length = 415

 Score =  425 bits (1092), Expect = e-118
 Identities = 215/375 (57%), Positives = 273/375 (72%), Gaps = 13/375 (3%)

Query: 18  PAPPQMGIENIPATLSHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSET 77
           P PP     N    +S       Y ++G+ F V  +Y   +  IG GAYG+VCSA ++ T
Sbjct: 2   PPPPTSDTSNFNDNIS-------YFVYGSQFTVPRRYSI-VKCIGHGAYGVVCSAKDNLT 53

Query: 78  NEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYE 137
            E VA+KKI+ AFDN  D KRTLREI LLRH  HEN+++I+DI+ P  +E F DVYI  E
Sbjct: 54  GEKVAIKKISKAFDNLKDTKRTLREIHLLRHFKHENLISIKDILKPNSKEQFEDVYIVSE 113

Query: 138 LMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKI 197
           LMDTDLHQII S Q LS++HCQYF+YQ+LRGLK+IHSANVLHRDLKPSNLL+N +C LKI
Sbjct: 114 LMDTDLHQIITSPQPLSDDHCQYFVYQMLRGLKHIHSANVLHRDLKPSNLLINEDCLLKI 173

Query: 198 CDFGLARVTSET--DFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPL 255
           CD GLARV   T   FMTEYV TRWYRAPE++L+ + YT AID+WSVGCIF EL+ RKPL
Sbjct: 174 CDLGLARVEDATHQGFMTEYVATRWYRAPEVILSWNKYTKAIDIWSVGCIFAELLGRKPL 233

Query: 256 FPGRDHVHQLRLLMELIGTPSEDDL-GFLNENAKRYIRQL--PPYRRQSFQEKFPQVHPE 312
           F G+D++HQ+ L++E IG+PSE+D+    NE A+++IR L      + +F   FP+ +P+
Sbjct: 234 FQGKDYIHQITLIIETIGSPSEEDICNIANEQARQFIRSLNMGNQPKVNFANMFPKANPD 293

Query: 313 AIDLVEKMLTFDPRKRITVEDALAHPYLTSLHDISDEPVCMTPFSFDFEQHALTEEQMKE 372
           AIDL+E+ML FDP KR+TVE+ALAHPY  SLHD SDEP+C+  FS +FE   L  + +KE
Sbjct: 294 AIDLLERMLYFDPSKRLTVEEALAHPYFQSLHDPSDEPICLHKFSLNFEAWDLNRDLLKE 353

Query: 373 LIYREALAFNPEYQQ 387
           LIY E LA++PE  Q
Sbjct: 354 LIYNEMLAYHPEDPQ 368


>NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF3
           (EC 2.7.1.37) (P43)
          Length = 372

 Score =  424 bits (1090), Expect = e-118
 Identities = 202/346 (58%), Positives = 270/346 (77%), Gaps = 4/346 (1%)

Query: 41  YNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTL 100
           Y+++ ++FE+  KY P I PIG+GAYGIVCS+ N ETNE VA+KKI NAF+N+IDA RTL
Sbjct: 19  YSMWQSLFEIDTKYVP-IKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTL 77

Query: 101 REIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQY 160
           RE+KLLRH+ HENV+A++D++ P  R  F DVY+ YELMDTDLHQII+S+Q LS +HCQY
Sbjct: 78  RELKLLRHLRHENVIALKDVMMPIHRRSFKDVYLVYELMDTDLHQIIKSSQTLSNDHCQY 137

Query: 161 FLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSETD-FMTEYVVTR 219
           FL+Q+LRGLKY+HSAN+LHRDLKP NLL+NANCDLKICDFGLAR +S  D FMTEYVVTR
Sbjct: 138 FLFQLLRGLKYLHSANILHRDLKPGNLLINANCDLKICDFGLARTSSGKDQFMTEYVVTR 197

Query: 220 WYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDD 279
           WYRAPELLL   +Y  +IDVWSVGCIF EL+ RKP+FPG + ++QL+L++ ++G+  E+D
Sbjct: 198 WYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQLKLIINILGSQREED 257

Query: 280 LGFL-NENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHP 338
           + F+ N  A++YI+ LP      F   +P  HP AIDL+++ML FDP KRI+V +AL HP
Sbjct: 258 IEFIDNPKARKYIKSLPYSPGTPFSRLYPHAHPLAIDLLQRMLVFDPSKRISVIEALQHP 317

Query: 339 YLTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPE 384
           Y++ L+D + +P    P + D ++  L EE ++E+++ E L ++PE
Sbjct: 318 YMSPLYDPNTDPPAQVPINLDIDED-LGEETIREMMWSEILEYHPE 362


>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC
           2.7.1.37) (MAP kinase 7) (AtMPK7)
          Length = 368

 Score =  415 bits (1067), Expect = e-116
 Identities = 195/346 (56%), Positives = 265/346 (76%), Gaps = 4/346 (1%)

Query: 41  YNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTL 100
           Y+++  +FE+  KY P I PIG+GAYG+VCS+ N ETNE VA+KKI N F+N++DA RTL
Sbjct: 19  YSMWQTLFEIDTKYVP-IKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTL 77

Query: 101 REIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQY 160
           RE+KLLRH+ HENV+A++D++ P  R  F DVY+ YELMDTDLHQII+S+Q+LS++HC+Y
Sbjct: 78  RELKLLRHVRHENVIALKDVMLPANRSSFKDVYLVYELMDTDLHQIIKSSQSLSDDHCKY 137

Query: 161 FLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSETD-FMTEYVVTR 219
           FL+Q+LRGLKY+HSAN+LHRDLKP NLL+NANCDLKICDFGLAR +   + FMTEYVVTR
Sbjct: 138 FLFQLLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTSQGNEQFMTEYVVTR 197

Query: 220 WYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDD 279
           WYRAPELLL   +Y  +IDVWSVGCIF E++ RKP+FPG + ++QL+L++ ++G+  E D
Sbjct: 198 WYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQESD 257

Query: 280 LGFL-NENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHP 338
           + F+ N  A+R+I+ LP  R       +PQ +P AIDL+++ML FDP KRI+V DAL HP
Sbjct: 258 IRFIDNPKARRFIKSLPYSRGTHLSNLYPQANPLAIDLLQRMLVFDPTKRISVTDALLHP 317

Query: 339 YLTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPE 384
           Y+  L D    P    P S D +++ + E  ++E+++ E L ++PE
Sbjct: 318 YMAGLFDPGSNPPAHVPISLDIDEN-MEEPVIREMMWNEMLYYHPE 362


>MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (EC
           2.7.1.37) (MAP kinase 1) (AtMPK1)
          Length = 370

 Score =  413 bits (1061), Expect = e-115
 Identities = 198/346 (57%), Positives = 264/346 (76%), Gaps = 4/346 (1%)

Query: 41  YNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTL 100
           ++++  +FE+  KY P I PIG+GAYG+VCS+ NS+TNE VA+KKI N ++N+IDA RTL
Sbjct: 19  FSMWQTLFEIDTKYMP-IKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTL 77

Query: 101 REIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQY 160
           RE+KLLRH+ HENV+A++D++ P  +  F DVY+ YELMDTDLHQII+S+Q LS +HCQY
Sbjct: 78  RELKLLRHLRHENVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIKSSQVLSNDHCQY 137

Query: 161 FLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVT-SETDFMTEYVVTR 219
           FL+Q+LRGLKYIHSAN+LHRDLKP NLL+NANCDLKICDFGLAR + ++  FMTEYVVTR
Sbjct: 138 FLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARASNTKGQFMTEYVVTR 197

Query: 220 WYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDD 279
           WYRAPELLL   +Y  +IDVWSVGCIF EL+ RKP+F G + ++QL+L++ ++G+  E+D
Sbjct: 198 WYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILGSQREED 257

Query: 280 LGFL-NENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHP 338
           L F+ N  AKRYIR LP     S    +P  H  AIDL++KML FDP KRI+V +AL HP
Sbjct: 258 LEFIDNPKAKRYIRSLPYSPGMSLSRLYPGAHVLAIDLLQKMLVFDPSKRISVSEALQHP 317

Query: 339 YLTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPE 384
           Y+  L+D +  P    P   D ++  L EE ++E+++ E L ++P+
Sbjct: 318 YMAPLYDPNANPPAQVPIDLDVDED-LREEMIREMMWNEMLHYHPQ 362


>MPK2_ARATH (Q39022) Mitogen-activated protein kinase homolog 2 (EC
           2.7.1.37) (MAP kinase 2) (AtMPK2)
          Length = 376

 Score =  409 bits (1051), Expect = e-114
 Identities = 205/372 (55%), Positives = 269/372 (72%), Gaps = 12/372 (3%)

Query: 16  AAPAPPQMGIENIPATLSHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNS 75
           A P  P  GI N       G  +  ++++  +FE+  KY P I PIG+GAYG+VCS+ N 
Sbjct: 2   ATPVDPPNGIRN------QGKHY--FSMWQTLFEIDTKYVP-IKPIGRGAYGVVCSSVNR 52

Query: 76  ETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIA 135
           E+NE VA+KKI N F+N+IDA RTLRE+KLLRH+ HENVVA++D++    +  F DVY+ 
Sbjct: 53  ESNERVAIKKIHNVFENRIDALRTLRELKLLRHLRHENVVALKDVMMANHKRSFKDVYLV 112

Query: 136 YELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDL 195
           YELMDTDLHQII+S+Q LS +HCQYFL+Q+LRGLKYIHSAN+LHRDLKP NLL+NANCDL
Sbjct: 113 YELMDTDLHQIIKSSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDL 172

Query: 196 KICDFGLARVT-SETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKP 254
           KICDFGLAR + ++  FMTEYVVTRWYRAPELLL   +Y  +IDVWSVGCIF EL+ RKP
Sbjct: 173 KICDFGLARTSNTKGQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKP 232

Query: 255 LFPGRDHVHQLRLLMELIGTPSEDDLGFL-NENAKRYIRQLPPYRRQSFQEKFPQVHPEA 313
           +FPG + ++Q++L++ ++G+  E+DL F+ N  AKRYI  LP     SF   +P  +  A
Sbjct: 233 VFPGTECLNQIKLIINILGSQREEDLEFIDNPKAKRYIESLPYSPGISFSRLYPGANVLA 292

Query: 314 IDLVEKMLTFDPRKRITVEDALAHPYLTSLHDISDEPVCMTPFSFDF-EQHALTEEQMKE 372
           IDL++KML  DP KRI+V +AL HPY+  L+D S  P    P   D  E   L  E ++E
Sbjct: 293 IDLLQKMLVLDPSKRISVTEALQHPYMAPLYDPSANPPAQVPIDLDVDEDEDLGAEMIRE 352

Query: 373 LIYREALAFNPE 384
           L+++E + ++PE
Sbjct: 353 LMWKEMIHYHPE 364


>MK01_BOVIN (P46196) Mitogen-activated protein kinase 1 (EC
           2.7.1.37) (Extracellular signal-regulated kinase 2)
           (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase
           2) (MAPK 2) (p42-MAPK) (ERT1)
          Length = 360

 Score =  365 bits (936), Expect = e-100
 Identities = 181/347 (52%), Positives = 244/347 (70%), Gaps = 8/347 (2%)

Query: 45  GNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIK 104
           G +F+V  +Y   +  IG+GAYG+VCSA+++     VA+KKI+  F+++   +RTLREIK
Sbjct: 16  GQVFDVGPRYTN-LSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIK 73

Query: 105 LLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQ 164
           +L    HEN++ I DI+  P  E   DVYI  +LM+TDL++++++ Q LS +H  YFLYQ
Sbjct: 74  ILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHICYFLYQ 132

Query: 165 ILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTS----ETDFMTEYVVTRW 220
           ILRGLKYIHSANVLHRDLKPSNLLLN  CDLKICDFGLARV       T F+TEYV TRW
Sbjct: 133 ILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRW 192

Query: 221 YRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDL 280
           YRAPE++LNS  YT +ID+WSVGCI  E++  +P+FPG+ ++ QL  ++ ++G+PS++DL
Sbjct: 193 YRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDL 252

Query: 281 G-FLNENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHPY 339
              +N  A+ Y+  LP   +  +   FP    +A+DL++KMLTF+P KRI VE ALAHPY
Sbjct: 253 NCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPY 312

Query: 340 LTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPEYQ 386
           L   +D SDEPV   PF FD E   L +E++KELI+ E   F P Y+
Sbjct: 313 LEQYYDPSDEPVAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYR 359


>MK01_HUMAN (P28482) Mitogen-activated protein kinase 1 (EC
           2.7.1.37) (Extracellular signal-regulated kinase 2)
           (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase
           2) (MAPK 2) (p42-MAPK) (ERT1)
          Length = 360

 Score =  364 bits (935), Expect = e-100
 Identities = 180/347 (51%), Positives = 244/347 (69%), Gaps = 8/347 (2%)

Query: 45  GNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIK 104
           G +F+V  +Y   +  IG+GAYG+VCSA+++     VA+KKI+  F+++   +RTLREIK
Sbjct: 16  GQVFDVGPRYTN-LSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIK 73

Query: 105 LLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQ 164
           +L    HEN++ I DI+  P  E   DVYI  +LM+TDL++++++ Q LS +H  YFLYQ
Sbjct: 74  ILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHICYFLYQ 132

Query: 165 ILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTS----ETDFMTEYVVTRW 220
           ILRGLKYIHSANVLHRDLKPSNLLLN  CDLKICDFGLARV       T F+TEYV TRW
Sbjct: 133 ILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRW 192

Query: 221 YRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDL 280
           YRAPE++LNS  YT +ID+WSVGCI  E++  +P+FPG+ ++ QL  ++ ++G+PS++DL
Sbjct: 193 YRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDL 252

Query: 281 G-FLNENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHPY 339
              +N  A+ Y+  LP   +  +   FP    +A+DL++KMLTF+P KRI VE ALAHPY
Sbjct: 253 NCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPY 312

Query: 340 LTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPEYQ 386
           L   +D SDEP+   PF FD E   L +E++KELI+ E   F P Y+
Sbjct: 313 LEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYR 359


>MK01_RAT (P63086) Mitogen-activated protein kinase 1 (EC 2.7.1.37)
           (Extracellular signal-regulated kinase 2) (ERK-2)
           (Mitogen-activated protein kinase 2) (MAP kinase 2)
           (MAPK 2) (p42-MAPK) (ERT1)
          Length = 358

 Score =  364 bits (934), Expect = e-100
 Identities = 180/347 (51%), Positives = 244/347 (69%), Gaps = 8/347 (2%)

Query: 45  GNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIK 104
           G +F+V  +Y   +  IG+GAYG+VCSA+++     VA+KKI+  F+++   +RTLREIK
Sbjct: 14  GQVFDVGPRYTN-LSYIGEGAYGMVCSAYDNLNKVRVAIKKIS-PFEHQTYCQRTLREIK 71

Query: 105 LLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQ 164
           +L    HEN++ I DI+  P  E   DVYI  +LM+TDL++++++ Q LS +H  YFLYQ
Sbjct: 72  ILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHICYFLYQ 130

Query: 165 ILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTS----ETDFMTEYVVTRW 220
           ILRGLKYIHSANVLHRDLKPSNLLLN  CDLKICDFGLARV       T F+TEYV TRW
Sbjct: 131 ILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRW 190

Query: 221 YRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDL 280
           YRAPE++LNS  YT +ID+WSVGCI  E++  +P+FPG+ ++ QL  ++ ++G+PS++DL
Sbjct: 191 YRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDL 250

Query: 281 G-FLNENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHPY 339
              +N  A+ Y+  LP   +  +   FP    +A+DL++KMLTF+P KRI VE ALAHPY
Sbjct: 251 NCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPY 310

Query: 340 LTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPEYQ 386
           L   +D SDEP+   PF FD E   L +E++KELI+ E   F P Y+
Sbjct: 311 LEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYR 357


>MK01_MOUSE (P63085) Mitogen-activated protein kinase 1 (EC
           2.7.1.37) (Extracellular signal-regulated kinase 2)
           (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase
           2) (MAPK 2) (p42-MAPK) (ERT1)
          Length = 358

 Score =  364 bits (934), Expect = e-100
 Identities = 180/347 (51%), Positives = 244/347 (69%), Gaps = 8/347 (2%)

Query: 45  GNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIK 104
           G +F+V  +Y   +  IG+GAYG+VCSA+++     VA+KKI+  F+++   +RTLREIK
Sbjct: 14  GQVFDVGPRYTN-LSYIGEGAYGMVCSAYDNLNKVRVAIKKIS-PFEHQTYCQRTLREIK 71

Query: 105 LLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQ 164
           +L    HEN++ I DI+  P  E   DVYI  +LM+TDL++++++ Q LS +H  YFLYQ
Sbjct: 72  ILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHICYFLYQ 130

Query: 165 ILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTS----ETDFMTEYVVTRW 220
           ILRGLKYIHSANVLHRDLKPSNLLLN  CDLKICDFGLARV       T F+TEYV TRW
Sbjct: 131 ILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRW 190

Query: 221 YRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDL 280
           YRAPE++LNS  YT +ID+WSVGCI  E++  +P+FPG+ ++ QL  ++ ++G+PS++DL
Sbjct: 191 YRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDL 250

Query: 281 G-FLNENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHPY 339
              +N  A+ Y+  LP   +  +   FP    +A+DL++KMLTF+P KRI VE ALAHPY
Sbjct: 251 NCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPY 310

Query: 340 LTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPEYQ 386
           L   +D SDEP+   PF FD E   L +E++KELI+ E   F P Y+
Sbjct: 311 LEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYR 357


>MK01_XENLA (P26696) Mitogen-activated protein kinase 1 (EC
           2.7.1.37) (Myelin XP42 protein kinase) (Myelin basic
           protein kinase) (MBP kinase) (M phase MAP kinase)
          Length = 361

 Score =  363 bits (933), Expect = e-100
 Identities = 182/346 (52%), Positives = 241/346 (69%), Gaps = 8/346 (2%)

Query: 45  GNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIK 104
           G  F+V  +Y   +  IG+GAYG+VCSAH +     VA+KKI+  F+++   +RTLREIK
Sbjct: 19  GQAFDVGPRYTN-LSYIGEGAYGMVCSAHCNINKVRVAIKKIS-PFEHQTYCQRTLREIK 76

Query: 105 LLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQ 164
           +L    HEN++ I DI+  P  E   DVYI  +LM+TDL++++++ Q LS +H  YFLYQ
Sbjct: 77  ILLRFKHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHICYFLYQ 135

Query: 165 ILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTS----ETDFMTEYVVTRW 220
           ILRGLKYIHSANVLHRDLKPSNLLLN  CDLKICDFGLARV       T F+TEYV TRW
Sbjct: 136 ILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRW 195

Query: 221 YRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEDDL 280
           YRAPE++LNS  YT +ID+WSVGCI  E++  +P+FPG+ ++ QL  ++ ++G+PS++DL
Sbjct: 196 YRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDL 255

Query: 281 G-FLNENAKRYIRQLPPYRRQSFQEKFPQVHPEAIDLVEKMLTFDPRKRITVEDALAHPY 339
              +N  A+ Y+  LP   +  +   FP   P+A+DL++KMLTF+P KRI VE ALAHPY
Sbjct: 256 NCIINLKARNYLLSLPHKNKVPWNRLFPNADPKALDLLDKMLTFNPHKRIEVEAALAHPY 315

Query: 340 LTSLHDISDEPVCMTPFSFDFEQHALTEEQMKELIYREALAFNPEY 385
           L   +D SDEPV   PF F+ E   L +E +KELI+ E   F P Y
Sbjct: 316 LEQYYDPSDEPVAEAPFKFEMELDDLPKETLKELIFEETARFQPGY 361


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.322    0.138    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,140,869
Number of Sequences: 164201
Number of extensions: 2099328
Number of successful extensions: 9374
Number of sequences better than 10.0: 1687
Number of HSP's better than 10.0 without gapping: 1566
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 4695
Number of HSP's gapped (non-prelim): 2120
length of query: 387
length of database: 59,974,054
effective HSP length: 112
effective length of query: 275
effective length of database: 41,583,542
effective search space: 11435474050
effective search space used: 11435474050
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)