BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC121237.19 + phase: 0 /pseudo
(754 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kina... 279 2e-74
M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kina... 277 6e-74
M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kina... 262 2e-69
WR19_ARATH (Q9SZ67) Probable WRKY transcription factor 19 (WRKY ... 233 1e-60
BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SS... 232 2e-60
M3K3_HUMAN (Q99759) Mitogen-activated protein kinase kinase kina... 229 3e-59
MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.1.-) 227 8e-59
M3K3_MOUSE (Q61084) Mitogen-activated protein kinase kinase kina... 227 1e-58
BYR2_SCHPO (P28829) Protein kinase byr2 (EC 2.7.1.-) (Protein ki... 226 2e-58
M3K2_HUMAN (Q9Y2U5) Mitogen-activated protein kinase kinase kina... 218 6e-56
M3K2_MOUSE (Q61083) Mitogen-activated protein kinase kinase kina... 214 7e-55
ST11_YEAST (P23561) Serine/threonine-protein kinase STE11 (EC 2.... 213 1e-54
WIS4_SCHPO (O14299) MAP kinase kinase kinase wis4 (EC 2.7.1.-) (... 203 2e-51
CC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.1.-) 196 2e-49
M3K1_HUMAN (Q13233) Mitogen-activated protein kinase kinase kina... 196 2e-49
M3K1_RAT (Q62925) Mitogen-activated protein kinase kinase kinase... 194 7e-49
M3K1_MOUSE (P53349) Mitogen-activated protein kinase kinase kina... 194 9e-49
M3K4_HUMAN (Q9Y6R4) Mitogen-activated protein kinase kinase kina... 191 8e-48
M3K4_MOUSE (O08648) Mitogen-activated protein kinase kinase kina... 189 2e-47
M4K3_RAT (Q924I2) Mitogen-activated protein kinase kinase kinase... 184 6e-46
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase
2 (EC 2.7.1.-) (Arabidospsis NPK1-related protein kinase
2)
Length = 651
Score = 279 bits (713), Expect = 2e-74
Identities = 155/318 (48%), Positives = 201/318 (62%), Gaps = 12/318 (3%)
Query: 360 DDGKQQSHRLPLPPLTVTN-TSPFSHSNSAATSPSMPRSPARADSPMSSGSRWKKGKLLG 418
DD Q++H P P L TS S A S S P + P RW+KG+L+G
Sbjct: 19 DDENQENHPPPFPSLLADKITSCIRKSMVFAKSQSPPNNSTVQIKPPI---RWRKGQLIG 75
Query: 419 RGTFGHVYIGFNSQSGEMCAMKEVTLFSDDA---KSLESAKQLMQEVHLLSRLRHPNIVQ 475
RG FG VY+G N SGE+ A+K+V + S+ A K+ ++L +EV LL L HPNIV+
Sbjct: 76 RGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHPNIVR 135
Query: 476 YYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSGLAYLHAKNTLHR 535
Y G+ D+ L I LE+V GGSI LL+++G F E +R+YT Q+L GL YLH +HR
Sbjct: 136 YLGTVREDETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLHNHAIMHR 195
Query: 536 DIKGANILVDPNGRVKVADFGMAKHITGQYC---PLSFKGSPYWMAPEVIKNSKECSLGV 592
DIKGANILVD G +K+ADFG +K + S KG+PYWMAPEVI + S
Sbjct: 196 DIKGANILVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGH-SFSA 254
Query: 593 DIWSLGCTVLEMATTKPPWS-QYEGVAAMFKIGNSKELPTIPDHLSNEGKDFVRKCLQRN 651
DIWS+GCTV+EM T K PWS QY+ +AA+F IG +K P IPD++S++ DF+ KCLQ+
Sbjct: 255 DIWSVGCTVIEMVTGKAPWSQQYKEIAAIFHIGTTKSHPPIPDNISSDANDFLLKCLQQE 314
Query: 652 PRDRPSASELLDHPFVKG 669
P RP+ASELL HPFV G
Sbjct: 315 PNLRPTASELLKHPFVTG 332
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase
1 (EC 2.7.1.-) (Arabidospsis NPK1-related protein kinase
1)
Length = 666
Score = 277 bits (709), Expect = 6e-74
Identities = 152/321 (47%), Positives = 198/321 (61%), Gaps = 14/321 (4%)
Query: 359 ADDGKQQSHRLPLPPLTVTNTSPFSHSNSAATSPSMPRSPARADSPMSSGSRWKKGKLLG 418
+ D Q ++ P P + + + PS P M+ W+KG+L+G
Sbjct: 17 SSDDDNQENQPPFPGVLADKITSCIRKSKIFIKPSFSPPPPANTVDMAPPISWRKGQLIG 76
Query: 419 RGTFGHVYIGFNSQSGEMCAMKEVTL---FSDDAKSLESAKQLMQEVHLLSRLRHPNIVQ 475
RG FG VY+G N SGE+ A+K+V + F+ K+ ++L +EV LL L HPNIV+
Sbjct: 77 RGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNIVR 136
Query: 476 YYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSGLAYLHAKNTLHR 535
Y G+ DD L I LE+V GGSI LL+++G F E +R+YT+Q+L GL YLH +HR
Sbjct: 137 YLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIMHR 196
Query: 536 DIKGANILVDPNGRVKVADFGMAKHI------TGQYCPLSFKGSPYWMAPEVIKNSKECS 589
DIKGANILVD G +K+ADFG +K + TG S KG+PYWMAPEVI + S
Sbjct: 197 DIKGANILVDNKGCIKLADFGASKQVAELATMTG---AKSMKGTPYWMAPEVILQTGH-S 252
Query: 590 LGVDIWSLGCTVLEMATTKPPWS-QYEGVAAMFKIGNSKELPTIPDHLSNEGKDFVRKCL 648
DIWS+GCTV+EM T K PWS QY+ VAA+F IG +K P IPD LS++ KDF+ KCL
Sbjct: 253 FSADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHPPIPDTLSSDAKDFLLKCL 312
Query: 649 QRNPRDRPSASELLDHPFVKG 669
Q P RP+ASELL HPFV G
Sbjct: 313 QEVPNLRPTASELLKHPFVMG 333
>M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kinase
3 (EC 2.7.1.-) (Arabidospsis NPK1-related protein kinase
3)
Length = 651
Score = 262 bits (670), Expect = 2e-69
Identities = 146/306 (47%), Positives = 191/306 (61%), Gaps = 15/306 (4%)
Query: 392 PSMPRSPARADSPMSSGSRWKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDA-- 449
P +P +P + ++P RW+KG+L+G G FG VY+G N SGE+ A+K+V + A
Sbjct: 53 PGLP-APRKEEAP---SIRWRKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASK 108
Query: 450 -KSLESAKQLMQEVHLLSRLRHPNIVQYYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQF 508
K+ ++L +EV LL L HPNIV+Y G+ D L I +E+V GGSI LL+++G F
Sbjct: 109 EKTQGHIRELEEEVQLLKNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSF 168
Query: 509 GELAIRSYTQQILSGLAYLHAKNTLHRDIKGANILVDPNGRVKVADFGMAKHITGQYC-- 566
E I YT+Q+L GL YLH +HRDIKGANILVD G +++ADFG +K +
Sbjct: 169 PEPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANILVDNKGCIRLADFGASKKVVELATVN 228
Query: 567 -PLSFKGSPYWMAPEVIKNSKECSLGVDIWSLGCTVLEMATTKPPWS-QYEGVAAMFKIG 624
S KG+PYWMAPEVI + S DIWS+GCTV+EMAT KPPWS QY+ AA+ IG
Sbjct: 229 GAKSMKGTPYWMAPEVILQTGH-SFSADIWSVGCTVIEMATGKPPWSEQYQQFAAVLHIG 287
Query: 625 NSKELPTIPDHLSNEGKDFVRKCLQRNPRDRPSASELLDHPFVKGAAPLERPI---MVPE 681
+K P IP+ LS E KDF+ KCL + P R SA+ELL HPFV G P + E
Sbjct: 288 RTKAHPPIPEDLSPEAKDFLMKCLHKEPSLRLSATELLQHPFVTGKRQEPYPAYRNSLTE 347
Query: 682 ASDPIT 687
+PIT
Sbjct: 348 CGNPIT 353
>WR19_ARATH (Q9SZ67) Probable WRKY transcription factor 19 (WRKY
DNA-binding protein 19)
Length = 1895
Score = 233 bits (595), Expect = 1e-60
Identities = 143/333 (42%), Positives = 195/333 (57%), Gaps = 16/333 (4%)
Query: 345 PRAGGTPTESQTGRADDGKQQSHRLPLPPLTVTNTSPFSHSNSAATSPSMPRSPARADSP 404
P P+ S R ++ + + PL T F+ + ++ SP A S
Sbjct: 1561 PETVAPPSSSSEAREEEVETEETGAMFIPLGDKETCSFTVNKGDSSRTISNTSPIYA-SE 1619
Query: 405 MSSGSRWKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDAKSLESAKQLMQEVHL 464
S + W+KG+LLGRG+ G VY G S G+ A KEV+L +++ E +Q+ + L
Sbjct: 1620 GSFITCWQKGQLLGRGSLGSVYEGI-SADGDFFAFKEVSLLDQGSQAHEWIQQVEGGIAL 1678
Query: 465 LSRLRHPNIVQYYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSGL 524
LS+L+H NIV+Y G+ + LYI+LE V+ GS+ KL Q Q G+ + YT+QIL GL
Sbjct: 1679 LSQLQHQNIVRYRGTTKDESNLYIFLELVTQGSLRKLYQR-NQLGDSVVSLYTRQILDGL 1737
Query: 525 AYLHAKNTLHRDIKGANILVDPNGRVKVADFGMAKHITGQYCPLSFKGSPY--WMAPEVI 582
YLH K +HR+IK AN+LVD NG VK+ADFG+AK +S +PY WMAPEVI
Sbjct: 1738 KYLHDKGFIHRNIKCANVLVDANGTVKLADFGLAK-------VMSLWRTPYWNWMAPEVI 1790
Query: 583 KNSKE---CSLGVDIWSLGCTVLEMATTKPPWSQYEGVAAMFKIGNSKELPTIPDHLSNE 639
N K+ DIWSLGCTVLEM T + P+S E A++ IG K LP IPD LS +
Sbjct: 1791 LNPKDYDGYGTPADIWSLGCTVLEMLTGQIPYSDLEIGTALYNIGTGK-LPKIPDILSLD 1849
Query: 640 GKDFVRKCLQRNPRDRPSASELLDHPFVKGAAP 672
+DF+ CL+ NP +RP+A+ELL+HPFV P
Sbjct: 1850 ARDFILTCLKVNPEERPTAAELLNHPFVNMPLP 1882
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31
(EC 2.7.1.37)
Length = 1478
Score = 232 bits (592), Expect = 2e-60
Identities = 120/265 (45%), Positives = 170/265 (63%), Gaps = 9/265 (3%)
Query: 411 WKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTL---FSDDAKSLESAKQLMQEVHLLSR 467
W KG+++G+G+FG VY+ N +GEM A+K+V + S + L + + L EV L
Sbjct: 1175 WMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKD 1234
Query: 468 LRHPNIVQYYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSGLAYL 527
L H NIVQY G E ++ ++LEYV+GGS+ L++ YG+F E I+ T Q+L GLAYL
Sbjct: 1235 LDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYL 1294
Query: 528 HAKNTLHRDIKGANILVDPNGRVKVADFGMAKHITGQY--CPLSFKGSPYWMAPEVIKNS 585
H+K LHRD+K N+L+D +G K++DFG+++ Y ++ +G+ +WMAPE++
Sbjct: 1295 HSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTK 1354
Query: 586 KECSLGVDIWSLGCTVLEMATTKPPWSQYEGVAAMFKIGNSKELPTIPDH----LSNEGK 641
+ S VDIWSLGC VLEM K PWS E VAAMFKIG SK P IP+ +S G+
Sbjct: 1355 QGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGR 1414
Query: 642 DFVRKCLQRNPRDRPSASELLDHPF 666
+F+ C + NP RP+A+ELL HPF
Sbjct: 1415 NFLDACFEINPEKRPTANELLSHPF 1439
>M3K3_HUMAN (Q99759) Mitogen-activated protein kinase kinase kinase
3 (EC 2.7.1.37) (MAPK/ERK kinase kinase 3) (MEK kinase
3) (MEKK 3)
Length = 626
Score = 229 bits (583), Expect = 3e-59
Identities = 120/272 (44%), Positives = 165/272 (60%), Gaps = 14/272 (5%)
Query: 406 SSGSRWKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDAKSLESAKQLMQEVHLL 465
S+ W++GKLLG+G FG VY+ ++ +G A K+V D ++ + L E+ LL
Sbjct: 357 SAPINWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLL 416
Query: 466 SRLRHPNIVQYYGS--ETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSG 523
L+H IVQYYG + + L I++EY+ GGS+ L+ YG E R YT+QIL G
Sbjct: 417 KNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEG 476
Query: 524 LAYLHAKNTLHRDIKGANILVDPNGRVKVADFGMAKHI-------TGQYCPLSFKGSPYW 576
++YLH+ +HRDIKGANIL D G VK+ DFG +K + TG S G+PYW
Sbjct: 477 MSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGM---RSVTGTPYW 533
Query: 577 MAPEVIKNSKECSLGVDIWSLGCTVLEMATTKPPWSQYEGVAAMFKIGNSKELPTIPDHL 636
M+PEVI + + D+WSLGCTV+EM T KPPW++YE +AA+FKI P +P H+
Sbjct: 534 MSPEVI-SGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHI 592
Query: 637 SNEGKDFVRKCLQRNPRDRPSASELLDHPFVK 668
S G+DF+R+ R RPSA ELL H F +
Sbjct: 593 SEHGRDFLRRIFV-EARQRPSAEELLTHHFAQ 623
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.1.-)
Length = 1116
Score = 227 bits (579), Expect = 8e-59
Identities = 122/290 (42%), Positives = 175/290 (60%), Gaps = 21/290 (7%)
Query: 400 RADSPMSSGS--------RWKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSD---- 447
+ D+ ++SGS +W KG+L+G GT+G V++ N +GE+ A+K+V +
Sbjct: 806 KPDTTITSGSVVSQNATFKWMKGELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGR 865
Query: 448 -DAKSLESAKQLMQEVHLLSRLRHPNIVQYYGSETVDDKLYIYLEYVSGGSIHKLLQEYG 506
D + + E+ +++ L H NIVQY G E + + I+LEYVSGGSI + L+ YG
Sbjct: 866 HDQLRKDIVDSINAEISMIADLDHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYG 925
Query: 507 QFGELAIRSYTQQILSGLAYLHAKNTLHRDIKGANILVDPNGRVKVADFGMAKHITGQY- 565
F E +R ++Q+L GL+YLH+K +HRD+K N+L+D +G K++DFG++KH Y
Sbjct: 926 PFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISKHSDNVYD 985
Query: 566 --CPLSFKGSPYWMAPEVIKNSKE-CSLGVDIWSLGCTVLEMATTKPPWSQYEGVAAMFK 622
LS +GS +WMAPEVI N + S VD+WSLGC VLEM + PWS E + AMFK
Sbjct: 986 NDANLSMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRRPWSTDEAIQAMFK 1045
Query: 623 IGNSKELPTIPDHL----SNEGKDFVRKCLQRNPRDRPSASELLDHPFVK 668
+G K+ P IP L S E F+ C N RP+A ELL+HPF+K
Sbjct: 1046 LGTEKKAPPIPSELVSQVSPEAIQFLNACFTVNADVRPTAEELLNHPFMK 1095
>M3K3_MOUSE (Q61084) Mitogen-activated protein kinase kinase kinase
3 (EC 2.7.1.37) (MAPK/ERK kinase kinase 3) (MEK kinase
3) (MEKK 3)
Length = 626
Score = 227 bits (578), Expect = 1e-58
Identities = 120/272 (44%), Positives = 165/272 (60%), Gaps = 14/272 (5%)
Query: 406 SSGSRWKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDAKSLESAKQLMQEVHLL 465
S+ W++GKLLG+G FG VY+ ++ +G A K+V D ++ + L E+ LL
Sbjct: 357 SAPINWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLL 416
Query: 466 SRLRHPNIVQYYGS--ETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSG 523
L+H IVQYYG + + L I++EY+ GGS+ L+ YG E R YT+QIL G
Sbjct: 417 KNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEG 476
Query: 524 LAYLHAKNTLHRDIKGANILVDPNGRVKVADFGMAKHI-------TGQYCPLSFKGSPYW 576
++YLH+ +HRDIKGANIL D G VK+ DFG +K + TG S G+PYW
Sbjct: 477 MSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTG---IRSVTGTPYW 533
Query: 577 MAPEVIKNSKECSLGVDIWSLGCTVLEMATTKPPWSQYEGVAAMFKIGNSKELPTIPDHL 636
M+PEVI + + D+WSLGCTV+EM T KPPW++YE +AA+FKI P +P H+
Sbjct: 534 MSPEVI-SGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHI 592
Query: 637 SNEGKDFVRKCLQRNPRDRPSASELLDHPFVK 668
S G+DF+R+ R RPSA ELL H F +
Sbjct: 593 SEHGRDFLRRIFV-EARQRPSAEELLTHHFAQ 623
>BYR2_SCHPO (P28829) Protein kinase byr2 (EC 2.7.1.-) (Protein
kinase ste8) (MAPK kinase kinase) (MAPKKK)
Length = 659
Score = 226 bits (575), Expect = 2e-58
Identities = 133/309 (43%), Positives = 182/309 (58%), Gaps = 30/309 (9%)
Query: 385 SNSAATSPSMPRSPARADSPMSSGS---------------RWKKGKLLGRGTFGHVYIGF 429
S S +SPS P+ SP S+ S +W +G L+G G+FG VY+G
Sbjct: 354 SFSPGSSPSFIEQPSPI-SPTSTTSEDTNTLEEDTDDQSIKWIRGALIGSGSFGQVYLGM 412
Query: 430 NSQSGEMCAMKEVTLFSDDAKSLESAK---QLMQEVHLLSRLRHPNIVQYYGSETVDDKL 486
N+ SGE+ A+K+V L S AK L E+ LL L H +IVQY GS D L
Sbjct: 413 NASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELSHEHIVQYLGSNLNSDHL 472
Query: 487 YIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSGLAYLHAKNTLHRDIKGANILVDP 546
I+LEYV GGS+ LL YG F E ++++ +Q L GL YLH++ +HRDIKGANILVD
Sbjct: 473 NIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHSRGIVHRDIKGANILVDN 532
Query: 547 NGRVKVADFGMAKHI--------TGQYCPLSFKGSPYWMAPEVIKNSKECSLGVDIWSLG 598
G++K++DFG++K + TG P SF+GS +WMAPEV+K + DIWSLG
Sbjct: 533 KGKIKISDFGISKKLELNSTSTKTGGARP-SFQGSSFWMAPEVVKQTMHTE-KTDIWSLG 590
Query: 599 CTVLEMATTKPPWSQYEGVAAMFKIGNSKELPTIPDHLSNEGKDFVRKCLQRNPRDRPSA 658
C V+EM T+K P+ + + A+F+IG + LP P ++S+ DF+ K + RP+A
Sbjct: 591 CLVIEMLTSKHPYPNCDQMQAIFRIGEN-ILPEFPSNISSSAIDFLEKTFAIDCNLRPTA 649
Query: 659 SELLDHPFV 667
SELL HPFV
Sbjct: 650 SELLSHPFV 658
>M3K2_HUMAN (Q9Y2U5) Mitogen-activated protein kinase kinase kinase
2 (EC 2.7.1.37) (MAPK/ERK kinase kinase 2) (MEK kinase
2) (MEKK 2)
Length = 618
Score = 218 bits (554), Expect = 6e-56
Identities = 127/305 (41%), Positives = 173/305 (56%), Gaps = 33/305 (10%)
Query: 372 PPLTVTNTSPFSHSNSAATSPSMPRSPARADSPMSSGSRWKKGKLLGRGTFGHVYIGFNS 431
P LTV + SP S S PR+P + W+ GKLLG+G FG VY+ ++
Sbjct: 335 PTLTVMDISPPSRS---------PRAP----------TNWRLGKLLGQGAFGRVYLCYDV 375
Query: 432 QSGEMCAMKEVTLFSDDAKSLESAKQLMQEVHLLSRLRHPNIVQYYGS--ETVDDKLYIY 489
+G A+K+V D ++ + L E+ LL H IVQYYG + + L I+
Sbjct: 376 DTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNFLHERIVQYYGCLRDPQEKTLSIF 435
Query: 490 LEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSGLAYLHAKNTLHRDIKGANILVDPNGR 549
+EY+ GGSI L+ YG E R YT+QIL G+ YLH+ LHRDIKGANIL D G
Sbjct: 436 MEYMPGGSIKDQLKAYGALTENGTRKYTRQILEGVHYLHSNMILHRDIKGANILRDSTGN 495
Query: 550 VKVADFGMAKHI-------TGQYCPLSFKGSPYWMAPEVIKNSKECSLGVDIWSLGCTVL 602
VK+ DFG +K + TG S G+PYWM+PEVI + + DIWS+ CTV+
Sbjct: 496 VKLGDFGASKRLQTICLSGTGM---KSVTGTPYWMSPEVI-SGQGYGRKADIWSVACTVV 551
Query: 603 EMATTKPPWSQYEGVAAMFKIGNSKELPTIPDHLSNEGKDFVRKCLQRNPRDRPSASELL 662
EM T KPPW+++E +AA+FKI P +P H+S+ +DF+++ + RPSA ELL
Sbjct: 552 EMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFV-EAKLRPSADELL 610
Query: 663 DHPFV 667
H FV
Sbjct: 611 RHMFV 615
>M3K2_MOUSE (Q61083) Mitogen-activated protein kinase kinase kinase
2 (EC 2.7.1.37) (MAPK/ERK kinase kinase 2) (MEK kinase
2) (MEKK 2)
Length = 619
Score = 214 bits (545), Expect = 7e-55
Identities = 125/305 (40%), Positives = 173/305 (55%), Gaps = 33/305 (10%)
Query: 372 PPLTVTNTSPFSHSNSAATSPSMPRSPARADSPMSSGSRWKKGKLLGRGTFGHVYIGFNS 431
P LTVT+ SP S S PR+P + W+ GKLLG+G FG VY+ ++
Sbjct: 336 PTLTVTDISPPSRS---------PRAP----------TNWRLGKLLGQGAFGRVYLCYDV 376
Query: 432 QSGEMCAMKEVTLFSDDAKSLESAKQLMQEVHLLSRLRHPNIVQYYGS--ETVDDKLYIY 489
+G A+K+V + ++ + L E+ LL L H IVQYYG + + L I+
Sbjct: 377 DTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIF 436
Query: 490 LEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSGLAYLHAKNTLHRDIKGANILVDPNGR 549
+E GGSI L+ YG E R YT+QIL G+ YLH+ +HRDIKGANIL D G
Sbjct: 437 MELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGN 496
Query: 550 VKVADFGMAKHI-------TGQYCPLSFKGSPYWMAPEVIKNSKECSLGVDIWSLGCTVL 602
+K+ DFG +K + TG S G+PYWM+PEVI + + DIWS+ CTV+
Sbjct: 497 IKLGDFGASKRLQTICLSGTGM---KSVTGTPYWMSPEVI-SGEGYGRKADIWSVACTVV 552
Query: 603 EMATTKPPWSQYEGVAAMFKIGNSKELPTIPDHLSNEGKDFVRKCLQRNPRDRPSASELL 662
EM T KPPW+++E +AA+FKI P +P H+S+ +DF+++ + RPSA ELL
Sbjct: 553 EMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFV-EAKLRPSAEELL 611
Query: 663 DHPFV 667
H FV
Sbjct: 612 RHMFV 616
>ST11_YEAST (P23561) Serine/threonine-protein kinase STE11 (EC
2.7.1.37)
Length = 738
Score = 213 bits (543), Expect = 1e-54
Identities = 121/306 (39%), Positives = 176/306 (56%), Gaps = 45/306 (14%)
Query: 405 MSSGSRWKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDD----------AKSLES 454
+++ W KG +G G+FG VY+G N+ +GE+ A+K+V + +++ A S E+
Sbjct: 430 IATPKNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDEN 489
Query: 455 AKQ-----------------------------LMQEVHLLSRLRHPNIVQYYGSETVDDK 485
+Q L E++LL L H NIV YYG+
Sbjct: 490 NEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGN 549
Query: 486 LYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSGLAYLHAKNTLHRDIKGANILVD 545
L I+LEYV GGS+ +L YG F E I ++T+QIL G+AYLH KN +HRDIKGANIL+D
Sbjct: 550 LNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILID 609
Query: 546 PNGRVKVADFGMAKHIT----GQYCPLSFKGSPYWMAPEVIKNSKECSLGVDIWSLGCTV 601
G VK+ DFG++K ++ Q S +GS +WM+PEV+K + + DIWS GC V
Sbjct: 610 IKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQT-ATTAKADIWSTGCVV 668
Query: 602 LEMATTKPPWSQYEGVAAMFKIGNSKELPTIPDHLSNEGKDFVRKCLQRNPRDRPSASEL 661
+EM T K P+ + + A+FKIG + P IP ++EGK+F+RK + + + RPSA EL
Sbjct: 669 IEMFTGKHPFPDFSQMQAIFKIG-TNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALEL 727
Query: 662 LDHPFV 667
L HP++
Sbjct: 728 LQHPWL 733
>WIS4_SCHPO (O14299) MAP kinase kinase kinase wis4 (EC 2.7.1.-) (MAP
kinase kinase kinase wak1) (MAP kinase kinase kinase
wik1)
Length = 1401
Score = 203 bits (516), Expect = 2e-51
Identities = 110/297 (37%), Positives = 170/297 (57%), Gaps = 17/297 (5%)
Query: 410 RWKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDAKSLESA-KQLMQEVHLLSRL 468
RW++G + G FG VY G N ++G++ A+KE+ L D+++ S Q+ E+ +L RL
Sbjct: 1036 RWQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKL--QDSRTFRSTVDQIHNEMTVLERL 1093
Query: 469 RHPNIVQYYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSGLAYLH 528
HPN+V YYG E +K+YI++E+ GGS+ LL E ++ Y Q+L GLAY+H
Sbjct: 1094 NHPNVVTYYGVEVHREKVYIFMEFCQGGSLADLLAHGRIEDENVLKVYVVQLLEGLAYIH 1153
Query: 529 AKNTLHRDIKGANILVDPNGRVKVADFGMAKHITGQYCP-----------LSFKGSPYWM 577
+++ LHRDIK ANIL+D G +K +DFG A +++ P G+P +M
Sbjct: 1154 SQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMYM 1213
Query: 578 APEVIKNSKECSLG-VDIWSLGCTVLEMATTKPPWSQYEGVAAMFKIGNSKELPTIP--D 634
APE+I +K+ G +DIWSLGC +LEM T PWS+ + A+ + P+IP +
Sbjct: 1214 APEIILGTKKGDFGAMDIWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAMHTPSIPQNE 1273
Query: 635 HLSNEGKDFVRKCLQRNPRDRPSASELLDHPFVKGAAPLERPIMVPEASDPITGITH 691
+S+ +DF+ +C +R+P RP A +LL HP++ M P T ++H
Sbjct: 1274 KISSLARDFIEQCFERDPEQRPRAVDLLTHPWITDFRKKTIITMPPATITKKTSLSH 1330
>CC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.1.-)
Length = 1062
Score = 196 bits (498), Expect = 2e-49
Identities = 108/255 (42%), Positives = 155/255 (60%), Gaps = 8/255 (3%)
Query: 414 GKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDAKSLESAKQLMQ-EVHLLSRLRHPN 472
G LG+G FG VY G N ++GE A+K+V L +K L+S +++ E+ LL L HPN
Sbjct: 12 GDCLGKGAFGAVYRGLNIKNGETVAVKKVKL----SKMLKSDLSVIKMEIDLLKNLDHPN 67
Query: 473 IVQYYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSGLAYLHAKNT 532
IV+Y GS +D L I LEY GS+ + + +G+ E + YT Q+L GL YLH +
Sbjct: 68 IVKYRGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQGV 127
Query: 533 LHRDIKGANILVDPNGRVKVADFGMAKHITGQYCPLSFKGSPYWMAPEVIKNSKECSLGV 592
+HRDIKGANIL +G +K+ADFG+A I S GSPYWMAPEVI+ +
Sbjct: 128 IHRDIKGANILTTKDGTIKLADFGVATKINALE-DHSVVGSPYWMAPEVIE-LVGATTAS 185
Query: 593 DIWSLGCTVLEMATTKPPWSQYEGVAAMFKIGNSKELPTIPDHLSNEGKDFVRKCLQRNP 652
DIWS+GCTV+E+ PP+ + +A+F++ E P +P ++S+ K F+ +C Q++P
Sbjct: 186 DIWSVGCTVIELLDGNPPYYDLDPTSALFRMVKD-EHPPLPSNISSAAKSFLMQCFQKDP 244
Query: 653 RDRPSASELLDHPFV 667
R +LL HP+V
Sbjct: 245 NLRIKTRKLLKHPWV 259
>M3K1_HUMAN (Q13233) Mitogen-activated protein kinase kinase kinase 1
(EC 2.7.1.37) (MAPK/ERK kinase kinase 1) (MEK kinase 1)
(MEKK 1) (Fragment)
Length = 1495
Score = 196 bits (497), Expect = 2e-49
Identities = 99/276 (35%), Positives = 161/276 (57%), Gaps = 11/276 (3%)
Query: 400 RADSPMSSGSRWKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDAKSLESAKQ-L 458
+A P + W KG+ +G G F Y + +G + A+K+VT + + E + L
Sbjct: 1215 KAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEAL 1274
Query: 459 MQEVHLLSRLRHPNIVQYYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQ 518
+E+ ++S L HPNI++ G+ +++E+++GGS+ LL +YG F E + +YT+
Sbjct: 1275 REEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTE 1334
Query: 519 QILSGLAYLHAKNTLHRDIKGANILVDPNG-RVKVADFGMAKHITGQYCPL-----SFKG 572
Q+L GL+YLH +HRD+KGAN+L+D G R+++ADFG A + + G
Sbjct: 1335 QLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLG 1394
Query: 573 SPYWMAPEVIKNSKECSLGVDIWSLGCTVLEMATTKPPWS---QYEGVAAMFKIGNSKEL 629
+ +MAPEV++ ++ D+WS+GC ++EMA KPPW+ +A +FKI ++
Sbjct: 1395 TIAFMAPEVLR-GQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTA 1453
Query: 630 PTIPDHLSNEGKDFVRKCLQRNPRDRPSASELLDHP 665
P+IP HLS +D +CL+ P+DRP + ELL HP
Sbjct: 1454 PSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHP 1489
>M3K1_RAT (Q62925) Mitogen-activated protein kinase kinase kinase 1
(EC 2.7.1.37) (MAPK/ERK kinase kinase 1) (MEK kinase 1)
(MEKK 1)
Length = 1493
Score = 194 bits (493), Expect = 7e-49
Identities = 98/276 (35%), Positives = 161/276 (57%), Gaps = 11/276 (3%)
Query: 400 RADSPMSSGSRWKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDAKSLESAKQ-L 458
+A+ P + W KG+ +G G F Y + +G + A+K+VT + + E + L
Sbjct: 1213 KANEPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEAL 1272
Query: 459 MQEVHLLSRLRHPNIVQYYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQ 518
+E+ ++S L HPNI++ G+ +++E+++G S+ LL +YG F E + +YT+
Sbjct: 1273 REEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGASVAHLLSKYGAFKESVVINYTE 1332
Query: 519 QILSGLAYLHAKNTLHRDIKGANILVDPNG-RVKVADFGMAKHITGQYCPL-----SFKG 572
Q+L GL+YLH +HRD+KGAN+L+D G R+++ADFG A + + G
Sbjct: 1333 QLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLG 1392
Query: 573 SPYWMAPEVIKNSKECSLGVDIWSLGCTVLEMATTKPPWS---QYEGVAAMFKIGNSKEL 629
+ +MAPEV++ ++ D+WS+GC ++EMA KPPW+ +A +FKI ++
Sbjct: 1393 TIAFMAPEVLR-GQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTA 1451
Query: 630 PTIPDHLSNEGKDFVRKCLQRNPRDRPSASELLDHP 665
P+IP HLS +D +CL+ P+DRP + ELL HP
Sbjct: 1452 PSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHP 1487
>M3K1_MOUSE (P53349) Mitogen-activated protein kinase kinase kinase 1
(EC 2.7.1.37) (MAPK/ERK kinase kinase 1) (MEK kinase 1)
(MEKK 1)
Length = 1493
Score = 194 bits (492), Expect = 9e-49
Identities = 98/276 (35%), Positives = 160/276 (57%), Gaps = 11/276 (3%)
Query: 400 RADSPMSSGSRWKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDAKSLESAKQ-L 458
+A P + W KG+ +G G F Y + +G + A+K+VT + + E + L
Sbjct: 1213 KAKQPYREDAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEAL 1272
Query: 459 MQEVHLLSRLRHPNIVQYYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQ 518
+E+ ++ L HPNI++ G+ +++E+++GGS+ LL +YG F E + +YT+
Sbjct: 1273 REEIRMMGHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTE 1332
Query: 519 QILSGLAYLHAKNTLHRDIKGANILVDPNG-RVKVADFGMAKHITGQYCPL-----SFKG 572
Q+L GL+YLH +HRD+KGAN+L+D G R+++ADFG A + + G
Sbjct: 1333 QLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLG 1392
Query: 573 SPYWMAPEVIKNSKECSLGVDIWSLGCTVLEMATTKPPWS---QYEGVAAMFKIGNSKEL 629
+ +MAPEV++ ++ D+WS+GC ++EMA KPPW+ +A +FKI ++
Sbjct: 1393 TIAFMAPEVLR-GQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTA 1451
Query: 630 PTIPDHLSNEGKDFVRKCLQRNPRDRPSASELLDHP 665
P+IP HLS +D +CL+ P+DRP + ELL HP
Sbjct: 1452 PSIPSHLSPGLRDVAVRCLELQPQDRPPSRELLKHP 1487
>M3K4_HUMAN (Q9Y6R4) Mitogen-activated protein kinase kinase kinase 4
(EC 2.7.1.37) (MAPK/ERK kinase kinase 4) (MEK kinase 4)
(MEKK 4) (MAP three kinase 1)
Length = 1607
Score = 191 bits (484), Expect = 8e-48
Identities = 111/287 (38%), Positives = 166/287 (57%), Gaps = 23/287 (8%)
Query: 397 SPARADSPMSSGSR-----WKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDAKS 451
+P D+ M G R W++G +G G +G VY + +GE+ AMKE+ +D K+
Sbjct: 1323 TPKSYDNVMHVGLRKVTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKT 1382
Query: 452 LESAKQLMQEVHLLSRLRHPNIVQYYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFG-- 509
+ K+ E+ + ++HPN+V+Y+G E +++YI++EY G+ L+E + G
Sbjct: 1383 I---KETADELKIFEGIKHPNLVRYFGVELHREEMYIFMEYCDEGT----LEEVSRLGLQ 1435
Query: 510 ELAIRSYTQQILSGLAYLHAKNTLHRDIKGANILVDPNGRVKVADFGMAKHITGQYCPL- 568
E IR Y++QI + LH +HRDIKGANI + +G +K+ DFG + + +
Sbjct: 1436 EHVIRLYSKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMP 1495
Query: 569 ----SFKGSPYWMAPEVIKNSKECSLG--VDIWSLGCTVLEMATTKPPWSQYE-GVAAMF 621
S G+ +MAPEVI +K G DIWSLGC V+EM T K PW +YE M+
Sbjct: 1496 GEVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMY 1555
Query: 622 KIGNSKELPTIPDHLSNEGKDFVRKCLQRNPRDRPSASELLDHPFVK 668
K+G + P IP+ LS EGKDF+ CL+ +P+ R +AS+LLDH FVK
Sbjct: 1556 KVGMGHK-PPIPERLSPEGKDFLSHCLESDPKMRWTASQLLDHSFVK 1601
>M3K4_MOUSE (O08648) Mitogen-activated protein kinase kinase kinase 4
(EC 2.7.1.37) (MAPK/ERK kinase kinase 4) (MEK kinase 4)
(MEKK 4)
Length = 1597
Score = 189 bits (480), Expect = 2e-47
Identities = 113/287 (39%), Positives = 166/287 (57%), Gaps = 23/287 (8%)
Query: 397 SPARADSPMSSGSR-----WKKGKLLGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDAKS 451
+P D+ M G R W++G +G G +G VY + +GE+ AMKE+ +D K+
Sbjct: 1313 TPKSYDNVMHVGLRKVTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKT 1372
Query: 452 LESAKQLMQEVHLLSRLRHPNIVQYYGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFG-- 509
+ K+ E+ + ++HPN+V+Y+G E +++YI++EY G+ L+E + G
Sbjct: 1373 I---KETADELKIFEGIKHPNLVRYFGVELHREEMYIFMEYCDEGT----LEEVSRLGLQ 1425
Query: 510 ELAIRSYTQQILSGLAYLHAKNTLHRDIKGANILVDPNGRVKVADFGMAKHI--TGQYCP 567
E IR YT+QI + LH +HRDIKGANI + +G +K+ DFG + + Q P
Sbjct: 1426 EHVIRLYTKQITVAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMP 1485
Query: 568 ---LSFKGSPYWMAPEVIKNSKECSLG--VDIWSLGCTVLEMATTKPPWSQYE-GVAAMF 621
S G+ +MAPEVI +K G DIWSLGC V+EM T K PW +YE M+
Sbjct: 1486 GEVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMY 1545
Query: 622 KIGNSKELPTIPDHLSNEGKDFVRKCLQRNPRDRPSASELLDHPFVK 668
K+G + P IP+ LS EGK F+ CL+ +P+ R +AS+LLDH FVK
Sbjct: 1546 KVGMGHK-PPIPERLSPEGKAFLSHCLESDPKIRWTASQLLDHAFVK 1591
>M4K3_RAT (Q924I2) Mitogen-activated protein kinase kinase kinase
kinase 3 (EC 2.7.1.37) (MAPK/ERK kinase kinase kinase 3)
(MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase
related protein kinase) (GLK) (Fragment)
Length = 862
Score = 184 bits (468), Expect = 6e-46
Identities = 109/283 (38%), Positives = 158/283 (55%), Gaps = 14/283 (4%)
Query: 417 LGRGTFGHVYIGFNSQSGEMCAMKEVTLFSDDAKSLESAKQLMQEVHLLSRLRHPNIVQY 476
+G GT+G VY N +GE+ A+K + L + E + QE+ ++ +H NIV Y
Sbjct: 11 IGSGTYGDVYKARNVNTGELAAIKVIKL-----EPGEDFAVVQQEIIMMKDCKHANIVAY 65
Query: 477 YGSETVDDKLYIYLEYVSGGSIHKLLQEYGQFGELAIRSYTQQILSGLAYLHAKNTLHRD 536
+GS DKL+I +E+ GGS+ + G EL I +++ L GL YLH+K +HRD
Sbjct: 66 FGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRD 125
Query: 537 IKGANILVDPNGRVKVADFGMAKHITGQYCP-LSFKGSPYWMAPEVIKNSKECSLG--VD 593
IKGANIL+ NG VK+ADFG++ IT SF G+PYWMAPEV ++ D
Sbjct: 126 IKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCD 185
Query: 594 IWSLGCTVLEMATTKPPWSQYEGVAAMFKIGNSK-ELPTIPDHL--SNEGKDFVRKCLQR 650
+W++G T +E+A +PP + A+F + S + P + D L SN FV+ L +
Sbjct: 186 LWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTK 245
Query: 651 NPRDRPSASELLDHPFVKGAAPLERPIMVPEASDPITGITHGT 693
NP+ RP+A +LL HPFV PL R + + E D + H T
Sbjct: 246 NPKKRPTAEKLLQHPFV--TQPLTRSLAI-ELLDKVNNPDHST 285
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.313 0.131 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,957,140
Number of Sequences: 164201
Number of extensions: 4683924
Number of successful extensions: 17998
Number of sequences better than 10.0: 1939
Number of HSP's better than 10.0 without gapping: 1536
Number of HSP's successfully gapped in prelim test: 410
Number of HSP's that attempted gapping in prelim test: 11878
Number of HSP's gapped (non-prelim): 3023
length of query: 754
length of database: 59,974,054
effective HSP length: 118
effective length of query: 636
effective length of database: 40,598,336
effective search space: 25820541696
effective search space used: 25820541696
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Medicago: description of AC121237.19