BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC137820.12 - phase: 0
(195 letters)
Database: nr
2,540,612 sequences; 863,360,394 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_701490.1| eukaryotic translation initiation factor 3 subu... 136 3e-31
ref|NP_080359.2| RIKEN cDNA 3110050K21 [Mus musculus] gi|6366410... 136 3e-31
ref|XP_612879.1| PREDICTED: similar to KIAA0853, partial [Bos ta... 136 4e-31
gb|AAH84352.1| LOC495149 protein [Xenopus laevis] 134 1e-30
gb|AAP37483.1| hypothetical protein [Homo sapiens] gi|31982941|r... 133 2e-30
emb|CAI16506.1| KIAA0853 [Homo sapiens] 133 2e-30
emb|CAI16505.1| KIAA0853 [Homo sapiens] gi|55859588|emb|CAI10903... 133 2e-30
emb|CAB66679.2| hypothetical protein [Homo sapiens] 133 2e-30
emb|CAD38544.1| hypothetical protein [Homo sapiens] 133 2e-30
ref|NP_067062.1| RNA binding motif protein 25 [Homo sapiens] 132 7e-30
gb|AAF19255.1|AC004858_3 U1 small ribonucleoprotein 1SNRP homolo... 132 7e-30
gb|AAC97961.1| S164 [Homo sapiens] 132 7e-30
emb|CAF96846.1| unnamed protein product [Tetraodon nigroviridis] 131 9e-30
ref|XP_635459.1| hypothetical protein DDB0219636 [Dictyostelium ... 131 1e-29
emb|CAG06679.1| unnamed protein product [Tetraodon nigroviridis] 131 1e-29
gb|EAA16423.1| eukaryotic translation initiation factor 3 subuni... 130 3e-29
gb|AAO30095.1| splicing factor-like protein [Arabidopsis thaliana] 129 5e-29
ref|XP_640578.1| hypothetical protein DDB0204606 [Dictyostelium ... 129 5e-29
dbj|BAB09409.1| splicing factor-like protein [Arabidopsis thaliana] 128 1e-28
ref|NP_568220.1| RNA recognition motif (RRM)-containing protein ... 128 1e-28
>ref|NP_701490.1| eukaryotic translation initiation factor 3 subunit 10, putative
[Plasmodium falciparum 3D7] gi|23496658|gb|AAN36214.1|
eukaryotic translation initiation factor 3 subunit 10,
putative [Plasmodium falciparum 3D7]
Length = 1377
Score = 136 bits (343), Expect = 3e-31
Identities = 79/181 (43%), Positives = 118/181 (64%), Gaps = 17/181 (9%)
Query: 27 SDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKER-HRSGRDRD 85
S + SYR+ D+ DGT RS+ R D R +DR+RD DRD++R HR RDRD
Sbjct: 1044 SQNGDDSYRRHDDHHDGTHRDRSEMRDRRDWSG-RDRDRDRERDRDRDRDREHRRDRDRD 1102
Query: 86 RDRDRDGERSSRDRDRDREKDRDREKD---RREKEKERER-----REREREKERERERSR 137
R+RDRD +R +RDRDR+++RDR++D RR+++++RER RER+R+++RER+R R
Sbjct: 1103 RERDRDRDR---ERDRDRDRERDRDRDREHRRDRDRDRERDRDRDRERDRDRDRERDRDR 1159
Query: 138 RSKSRSERDREIERE---ERERSRRSISRSERDRERERE-ERDRSRRSRSRSERDFEMRD 193
+ R +RDR+ ER+ +RER R +RDR+RER+ +RDR R +RD +++
Sbjct: 1160 DREHRRDRDRDRERDRDRDRERDRDRDRERDRDRDRERDRDRDRERERDRDRDRDRDIKR 1219
Query: 194 S 194
S
Sbjct: 1220 S 1220
Score = 134 bits (336), Expect = 2e-30
Identities = 76/193 (39%), Positives = 116/193 (59%), Gaps = 11/193 (5%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVS 63
D ++ + E+ D+ D+ R RD + ++ R D D ER
Sbjct: 1056 DHHDGTHRDRSEMRDRRDWSGRDRDRDRERDRDRDRDREHRRDRDRDRERDRDRDRERDR 1115
Query: 64 KKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKD-RREKEKERER 122
+DR+RD DRD+E HR RDRDR+RDRD +R RDRDRDRE+DRDR+++ RR+++++RER
Sbjct: 1116 DRDRERDRDRDRE-HRRDRDRDRERDRDRDRE-RDRDRDRERDRDRDREHRRDRDRDRER 1173
Query: 123 -REREREKERERERSRRSKSRSERDREIERE-ERERSRRSISRSERDREREREERDRSRR 180
R+R+RE++R+R+R R ERDR+ +RE ER+R R +RDR+ +R +RD +
Sbjct: 1174 DRDRDRERDRDRDRERDRDRDRERDRDRDRERERDRDR------DRDRDIKRSDRDHKKD 1227
Query: 181 SRSRSERDFEMRD 193
+ +RD R+
Sbjct: 1228 RDDKLDRDSRRRE 1240
Score = 124 bits (311), Expect = 1e-27
Identities = 75/178 (42%), Positives = 112/178 (62%), Gaps = 10/178 (5%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDR 73
E D+D + D+ R RD D ++ +R D D ER +DR+RD DR
Sbjct: 1094 EHRRDRDRDRERDRDRDRERDRDRDRERDRDRDREHRR--DRDRDRERDRDRDRERDRDR 1151
Query: 74 DKERHRSGRDRD--RDRDRDGERSSRDRDRDREKDRDREKDR-REKEKERERREREREKE 130
D+ER R RDR+ RDRDRD ER RDRDR+R++DRDRE+DR R++E++R+ R+RERE++
Sbjct: 1152 DRERDRD-RDREHRRDRDRDRERD-RDRDRERDRDRDRERDRDRDRERDRD-RDRERERD 1208
Query: 131 RERERSRRSKSRSERDREIEREER-ERSRRSISRSERDREREREERDRSRRSRSRSER 187
R+R+R R K RS+RD + +R+++ +R R RS + ++ E D S+R+ + ER
Sbjct: 1209 RDRDRDRDIK-RSDRDHKKDRDDKLDRDSRRRERSGKPENEKKRENDISKRNGTTEER 1265
Score = 122 bits (307), Expect = 4e-27
Identities = 68/178 (38%), Positives = 111/178 (62%), Gaps = 12/178 (6%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTE--EKRSKRRSSGDGDDERVSKKDRDRDDDRDK 75
D++ ++ D+ R R RD D E+ R D D +R ++DRDRD +RD+
Sbjct: 1082 DRERDRDRDRDREHRRDRDRDRERDRDRDRERDRDRDRERDRDRDREHRRDRDRDRERDR 1141
Query: 76 ERHRS-GRDRDRDRDRDGERSSRDRDRDREKDRDREKDR-REKEKERER-REREREKERE 132
+R R RDRDR+RDRD +R R RDRDR+++RDR++DR R+++++RER R+R+RE++R+
Sbjct: 1142 DRDRERDRDRDRERDRDRDREHR-RDRDRDRERDRDRDRERDRDRDRERDRDRDRERDRD 1200
Query: 133 RERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSERDFE 190
R+R R +RDR+I+R +R+ + +RD + +R+ R R R + +E+ E
Sbjct: 1201 RDRERERDRDRDRDRDIKRSDRDH------KKDRDDKLDRDSRRRERSGKPENEKKRE 1252
Score = 122 bits (305), Expect = 7e-27
Identities = 65/173 (37%), Positives = 109/173 (62%), Gaps = 9/173 (5%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKER 77
D+D +++ D+ R R+ D E R R + D +R ++DRDRD +RD++R
Sbjct: 1100 DRDRERDRDRDRERDRDRDRERDRDRDREHRRDRDRDRERDRDRDRERDRDRDRERDRDR 1159
Query: 78 ---HRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERER-REREREKERER 133
HR RDRDR+RDRD +R RDRDRDRE+DRDR+ RE++++R+R RER+R+++R+R
Sbjct: 1160 DREHRRDRDRDRERDRDRDRE-RDRDRDRERDRDRD---RERDRDRDRERERDRDRDRDR 1215
Query: 134 ERSRRSKS-RSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRS 185
+ R + + +RD +++R+ R R R +E+ RE + +R+ + R+++
Sbjct: 1216 DIKRSDRDHKKDRDDKLDRDSRRRERSGKPENEKKRENDISKRNGTTEERTKN 1268
Score = 119 bits (299), Expect = 4e-26
Identities = 78/184 (42%), Positives = 116/184 (62%), Gaps = 25/184 (13%)
Query: 15 ELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKD------RD 68
E++ + +K E S ++ERS+RK I+D +R + S +GDD D RD
Sbjct: 1006 EMDLQMKRKKEESRRSERSHRK-SSIDDDLTWRRGDKGGSQNGDDSYRRHDDHHDGTHRD 1064
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR-REKEKERERRERER 127
R + RD+ R SGRDRDRDR+RD RDRDR+++ R++DR RE++++R+ RER+R
Sbjct: 1065 RSEMRDR-RDWSGRDRDRDRERD-------RDRDRDREHRRDRDRDRERDRDRD-RERDR 1115
Query: 128 EKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE-ERDRSRRSRSRSE 186
+++RER+R R + R +RDR+ ER +R+R R ERDR+R+RE +RDR R R +
Sbjct: 1116 DRDRERDRDRDREHRRDRDRDRER-DRDRDR------ERDRDRDRERDRDRDREHRRDRD 1168
Query: 187 RDFE 190
RD E
Sbjct: 1169 RDRE 1172
Score = 100 bits (248), Expect = 3e-20
Identities = 70/218 (32%), Positives = 111/218 (50%), Gaps = 34/218 (15%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER 61
D D ++ E D+D + D+ R RD D ++ +R D D ER
Sbjct: 1116 DRDRERDRDRDREHRRDRDRDRERDRDRDRERDRDRDRERDRDRDREHRR--DRDRDRER 1173
Query: 62 VSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERS---SRDRDRD-REKDRDREKDRREK- 116
+DR+RD DRD+ER R RDR+RDRDRD ER RDRDRD + DRD +KDR +K
Sbjct: 1174 DRDRDRERDRDRDRERDRD-RDRERDRDRDRERERDRDRDRDRDIKRSDRDHKKDRDDKL 1232
Query: 117 EKERERRER----EREKERERERSRRSKSRSER-----------DREIEREERERSRRS- 160
+++ RRER E EK+RE + S+R+ + ER D + + E E + +S
Sbjct: 1233 DRDSRRRERSGKPENEKKRENDISKRNGTTEERTKNAWNLKEDDDSKAKHETSEENTKSW 1292
Query: 161 ----------ISRSERDREREREERDRSRRSRSRSERD 188
I ++E+ ++ E+++ ++++ S ++
Sbjct: 1293 RNNNKVIDNEIEKAEKYKDGEKKDGEKNKDENSSKNKE 1330
Score = 72.0 bits (175), Expect = 9e-12
Identities = 58/207 (28%), Positives = 95/207 (45%), Gaps = 30/207 (14%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
EK E +D + + ER R+ +E EE K++ E +SK R+R
Sbjct: 944 EKIQRAKERRDQHIRKLKAEEERKRREEEEERLLKEEMERKKKEEARKKLEEISKAQRER 1003
Query: 70 DDDRDKERHRSGRDRDRDRDRDGERSSRDRDRD----------------REKDRDREKDR 113
D + D + R ++ R +R +SS D D R D +
Sbjct: 1004 DLEMDLQMKRK-KEESRRSERSHRKSSIDDDLTWRRGDKGGSQNGDDSYRRHDDHHDGTH 1062
Query: 114 REKEKERERRE---REREKERERERSRRSKSRSERDREIE-REERERSRRSISRSERDRE 169
R++ + R+RR+ R+R+++RER+R +RDR+ E R +R+R R +R+R+
Sbjct: 1063 RDRSEMRDRRDWSGRDRDRDRERDR--------DRDRDREHRRDRDRDRERDRDRDRERD 1114
Query: 170 RERE-ERDRSRRSRSRSERDFEMRDSR 195
R+R+ ERDR R R +RD + R
Sbjct: 1115 RDRDRERDRDRDREHRRDRDRDRERDR 1141
Score = 59.3 bits (142), Expect = 6e-08
Identities = 44/200 (22%), Positives = 80/200 (40%), Gaps = 14/200 (7%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER 61
D D ++ + D+D + D+ R RD D ++ +R D D +
Sbjct: 1158 DRDREHRRDRDRDRERDRDRDRERDRDRDRERDRDRDRERDRDRDRERERDRDRDRDRD- 1216
Query: 62 VSKKDRDRDDDRD-------KERHRSGR---DRDRDRD---RDGERSSRDRDRDREKDRD 108
+ + DRD DRD + R RSG+ ++ R+ D R+G R ++ K+ D
Sbjct: 1217 IKRSDRDHKKDRDDKLDRDSRRRERSGKPENEKKRENDISKRNGTTEERTKNAWNLKEDD 1276
Query: 109 REKDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDR 168
K + E +E + R K + E + K + ++ E+ + E S ++ E
Sbjct: 1277 DSKAKHETSEENTKSWRNNNKVIDNEIEKAEKYKDGEKKDGEKNKDENSSKNKENDELAN 1336
Query: 169 EREREERDRSRRSRSRSERD 188
E E D +++ D
Sbjct: 1337 GNEENENDEVKKNDDEEASD 1356
Score = 47.4 bits (111), Expect = 2e-04
Identities = 53/234 (22%), Positives = 99/234 (41%), Gaps = 50/234 (21%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRD-EIEDGTEEKRSKRRSSGDGDDERV 62
++ E L + + E++ E++ K + Y K +IE+ T+ + R + +
Sbjct: 874 EDTEILLQEQKAAEEEQKADFEAALKEKEEYVKFSIDIEEFTKNEMKLRVE--EFEKNLK 931
Query: 63 SKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERER 122
++K+R + ++++ R+ RD+ + R R R+ E++R +++ K+KE R
Sbjct: 932 AQKERLYNILKEEKIQRAKERRDQHIRKLKAEEERKR-REEEEERLLKEEMERKKKEEAR 990
Query: 123 RERER----EKERERERSRRSKSRSERDREIEREERE----------------------- 155
++ E ++ER+ E + K + E R ER R+
Sbjct: 991 KKLEEISKAQRERDLEMDLQMKRKKEESRRSERSHRKSSIDDDLTWRRGDKGGSQNGDDS 1050
Query: 156 ------------------RSRRSISRSERDRERERE-ERDRSRRSRSRSERDFE 190
R RR S +RDR+RER+ +RDR R R +RD E
Sbjct: 1051 YRRHDDHHDGTHRDRSEMRDRRDWSGRDRDRDRERDRDRDRDREHRRDRDRDRE 1104
Score = 47.4 bits (111), Expect = 2e-04
Identities = 31/97 (31%), Positives = 51/97 (51%), Gaps = 12/97 (12%)
Query: 103 REKDRDREKDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSIS 162
+E+ R K+RR++ + + E ER K RE E R K ER + +EE + IS
Sbjct: 942 KEEKIQRAKERRDQHIRKLKAEEER-KRREEEEERLLKEEMERKK---KEEARKKLEEIS 997
Query: 163 RSERDRE--------REREERDRSRRSRSRSERDFEM 191
+++R+R+ R++EE RS RS +S D ++
Sbjct: 998 KAQRERDLEMDLQMKRKKEESRRSERSHRKSSIDDDL 1034
Score = 37.7 bits (86), Expect = 0.18
Identities = 29/94 (30%), Positives = 49/94 (51%), Gaps = 9/94 (9%)
Query: 99 RDRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSR 158
R + EK+ +K+R + E+ +R KER + R+ K+ ER R REE E
Sbjct: 922 RVEEFEKNLKAQKERLYNILKEEKIQRA--KERRDQHIRKLKAEEERKR---REEEE--- 973
Query: 159 RSISRSERDREREREERDRSRR-SRSRSERDFEM 191
+ + E +R+++ E R + S+++ ERD EM
Sbjct: 974 ERLLKEEMERKKKEEARKKLEEISKAQRERDLEM 1007
>ref|NP_080359.2| RIKEN cDNA 3110050K21 [Mus musculus] gi|63664104|ref|XP_619266.1|
PREDICTED: RIKEN cDNA 3110050K21 [Mus musculus]
Length = 1729
Score = 136 bits (343), Expect = 3e-31
Identities = 78/182 (42%), Positives = 113/182 (61%), Gaps = 19/182 (10%)
Query: 27 SDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRS------ 80
S++ ER R+ + D +E+R R D D ER +++R+R+ +R+KER R
Sbjct: 712 SEELERDERREERRIDRVDERRDDRVRDRDRDREREREREREREREREKERERELERERA 771
Query: 81 -----GRDRDRDRDRDGERSSRDRD--RDREKDRDREKDRREKEKERERREREREKERER 133
R+++R+R+R+ ER RDRD R+RE++R+RE REKE+ERER ERERE+ERER
Sbjct: 772 REREREREKERERERERERDQRDRDHDRERERERERE---REKEREREREERERERERER 828
Query: 134 ERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSERDFEMRD 193
ER R + ER+RE ER ERER+R ER+R+RE E++D+ R R D +R+
Sbjct: 829 ERERERERERERERERER-ERERARE--REKERERQREWEDKDKGRDDRREKREDIHVRE 885
Query: 194 SR 195
R
Sbjct: 886 DR 887
Score = 123 bits (309), Expect = 2e-27
Identities = 80/193 (41%), Positives = 115/193 (59%), Gaps = 16/193 (8%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKR--SKRRSSGDGDD-ERVSKKDRDRDDDRD 74
++D++ ER + +RD ++ ++R S R G ++ ER +++ R D D
Sbjct: 671 ERDTRDPARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRSEELERDERREERRIDRVD 730
Query: 75 KERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR---REKEKERER-REREREKE 130
+ R RDRDRDR+R+ ER R+R+R+REK+R+RE +R RE+E+ERE+ RERERE+E
Sbjct: 731 ERRDDRVRDRDRDRERERER-EREREREREKERERELERERAREREREREKERERERERE 789
Query: 131 R-------ERERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE-ERDRSRRSR 182
R +RER R + E++RE EREERER R ER+RERERE ER+R R
Sbjct: 790 RDQRDRDHDREREREREREREKEREREREERERERERERERERERERERERERERERERE 849
Query: 183 SRSERDFEMRDSR 195
ER+ E R
Sbjct: 850 RAREREKERERQR 862
Score = 115 bits (287), Expect = 9e-25
Identities = 66/188 (35%), Positives = 111/188 (58%), Gaps = 7/188 (3%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
E+ + + D+D + ++ R+R++ + E+ R + + ER +++R+R
Sbjct: 731 ERRDDRVRDRDRDREREREREREREREREKERERELERERAREREREREKERERERERER 790
Query: 70 DD---DRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR-REKEKERER-RE 124
D D D+ER R R+R+R+++R+ ER R+R+R+RE++R+RE++R RE+E+ERER RE
Sbjct: 791 DQRDRDHDRERERE-REREREKEREREREERERERERERERERERERERERERERERERE 849
Query: 125 REREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSR 184
R RE+E+ERER R + + ++ R+ RE+RE R RD ER+ + R R S
Sbjct: 850 RAREREKERERQREWEDK-DKGRDDRREKREDIHVREDRIPRDSHEERKSKKRYRNEGSP 908
Query: 185 SERDFEMR 192
S R R
Sbjct: 909 SPRQSPKR 916
Score = 105 bits (262), Expect = 7e-22
Identities = 58/168 (34%), Positives = 100/168 (59%), Gaps = 9/168 (5%)
Query: 15 ELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRD 74
E E + K+ E + ER+ + E E E +R + R D D +R +++R+R+ +++
Sbjct: 753 EREREREKERERELERERAREREREREKERERERERERDQRDRDHDREREREREREREKE 812
Query: 75 KERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR---REKEKERERREREREKER 131
+ER R R+R+R+R+R+ ER R+R+R+RE++R+RE++R REKE+ER+R +++K R
Sbjct: 813 REREREERERERERERERERE-RERERERERERERERERAREREKERERQREWEDKDKGR 871
Query: 132 ERERSRRS-----KSRSERDREIEREERERSRRSISRSERDREREREE 174
+ R +R + R RD ER+ ++R R S S R + R E
Sbjct: 872 DDRREKREDIHVREDRIPRDSHEERKSKKRYRNEGSPSPRQSPKRRRE 919
Score = 103 bits (256), Expect = 3e-21
Identities = 75/193 (38%), Positives = 103/193 (52%), Gaps = 19/193 (9%)
Query: 15 ELEDKDSKKN-ESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDR 73
+++ S N S +T SY +RD + R R + D ER +RDR D+R
Sbjct: 643 QMDSHSSGSNYHDSWETRSSYPERDRYPE-----RDTRDPARDSSFER-RHGERDRRDNR 696
Query: 74 DKERHRS------GRDRDRDRDRDGERSSRDRDRDREKDRDREKDR-REKEKERERRERE 126
++++ S GR + +RD E DR +R DR R++DR RE+E+ERER ERE
Sbjct: 697 ERDQRPSSPIRHQGRSEELERDERREERRIDRVDERRDDRVRDRDRDRERERERER-ERE 755
Query: 127 REKERERERSRRSKSRSERDREIERE-ERERSRRSISRS---ERDREREREERDRSRRSR 182
RE+E+ERER + ER+RE E+E ERER R R +R+RERERE R R
Sbjct: 756 REREKERERELERERAREREREREKERERERERERDQRDRDHDREREREREREREKERER 815
Query: 183 SRSERDFEMRDSR 195
R ER+ E R
Sbjct: 816 EREERERERERER 828
Score = 96.7 bits (239), Expect = 3e-19
Identities = 71/220 (32%), Positives = 106/220 (47%), Gaps = 32/220 (14%)
Query: 8 YLEKTVEELEDKDSKKNES-----SDKTERSYRKRDEI-EDGTEEKR-SKRRSSGDGDDE 60
+L + +E ++ +NES +D+ RS + E+ E G+ R S+ S G +
Sbjct: 594 HLREESSRVELRNDSRNESRSEIRNDRMGRSRGRGPELPEKGSRGTRGSQMDSHSSGSNY 653
Query: 61 RVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDR------------- 107
S + R +RD+ R RD RD + RDR +RE+D+
Sbjct: 654 HDSWETRSSYPERDRYPERDTRDPARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRSE 713
Query: 108 DREKDRREKEKERER-----------REREREKERERERSRRSKSRSERDREIEREE-RE 155
+ E+D R +E+ +R R+R+RE+ERERER R + ER+RE+ERE RE
Sbjct: 714 ELERDERREERRIDRVDERRDDRVRDRDRDREREREREREREREREKERERELERERARE 773
Query: 156 RSRRSISRSERDREREREERDRSRRSRSRSERDFEMRDSR 195
R R ER+RERER++RDR ER+ E R
Sbjct: 774 REREREKERERERERERDQRDRDHDREREREREREREKER 813
Score = 82.8 bits (203), Expect = 5e-15
Identities = 67/193 (34%), Positives = 100/193 (51%), Gaps = 16/193 (8%)
Query: 11 KTVEELEDKDSKKNESSDKT-ERSYR----KRDEIEDGTEEKR------SKRRSSGDGDD 59
K V +D +K +S + T ER R KR E T R S RRSS + D
Sbjct: 1290 KRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDR 1349
Query: 60 ERVSKKDRDRDDDRDKERHRSGRDRDRDRDR-DGERSSRDRDRDREKDRDREKDR-REKE 117
+ S+ DR +ER R DR+R+RDR D + DR+ ++E R R++DR RE++
Sbjct: 1350 QVHSRSGSFDSRDRLQERDRYEHDRERERDRRDPRQREWDREAEKEWPRTRDRDRLRERD 1409
Query: 118 KERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISR--SERDREREREER 175
++R+RR R+ ++ERER S + ER+R E + E +RS + SE +R+ E R
Sbjct: 1410 RDRDRR-RDLDRERERLISDPMERDRERERTFETSQLESGKRSEVKLESEHERDLEGSSR 1468
Query: 176 DRSRRSRSRSERD 188
D + R +RD
Sbjct: 1469 DSVALDKERMDRD 1481
Score = 74.3 bits (181), Expect = 2e-12
Identities = 48/188 (25%), Positives = 89/188 (46%), Gaps = 12/188 (6%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRS-SGDGDDERVSKKDRDRDDDRDKE 76
D++ ++ ++ + R+R+E E E +R + R + + ER +++R+R +R+KE
Sbjct: 798 DREREREREREREKEREREREERERERERERERERERERERERERERERERERAREREKE 857
Query: 77 RHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERRE----------RE 126
R R D+D+ RD R R+ RE R+ K K+R R E R
Sbjct: 858 RERQREWEDKDKGRDDRREKREDIHVREDRIPRDSHEERKSKKRYRNEGSPSPRQSPKRR 917
Query: 127 REKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRS-RSRS 185
RE + + ++E+ R + + R + RS+S S +R+ ++ R+S R S
Sbjct: 918 REHSPDSDTYHSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKSERKES 977
Query: 186 ERDFEMRD 193
R +E ++
Sbjct: 978 SRRYEEQE 985
Score = 67.8 bits (164), Expect = 2e-10
Identities = 65/227 (28%), Positives = 96/227 (41%), Gaps = 42/227 (18%)
Query: 11 KTVEELEDKDSKKNESSDKTERSYRKRDEIEDG-------TEEKRSKRRSSGDGDDERVS 63
+ V ++ D ++ + R R ++ DG EE RS R+ + RV
Sbjct: 544 RDVRDVRDVRDARDVRDVRDARDVRDVRDVRDGHRKEDVYQEEARSYGRNHLREESSRVE 603
Query: 64 KKDRDRDDDRDKERH-RSGRDRDRDRD--RDGERSSRDRDRDR----------------- 103
++ R++ R + R+ R GR R R + G R +R D
Sbjct: 604 LRNDSRNESRSEIRNDRMGRSRGRGPELPEKGSRGTRGSQMDSHSSGSNYHDSWETRSSY 663
Query: 104 -EKDRDREKDRREKEKER--ERREREREKERERERSRRSKS------RSERDREIEREER 154
E+DR E+D R+ ++ ERR ER++ RER +R S RSE ER E
Sbjct: 664 PERDRYPERDTRDPARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRSEELERDERREE 723
Query: 155 ER-----SRRSISRSERDRERERE-ERDRSRRSRSRSERDFEMRDSR 195
R RR +RDR+RERE ER+R R ER+ E+ R
Sbjct: 724 RRIDRVDERRDDRVRDRDRDREREREREREREREREKERERELERER 770
Score = 67.0 bits (162), Expect = 3e-10
Identities = 45/142 (31%), Positives = 68/142 (47%), Gaps = 6/142 (4%)
Query: 60 ERVSKKDRDRDDDRDKERH---RSGRDRDRDRDRDGE-RSSRDRDRDREKDRDREKDRRE 115
+R R R R+K RH R+ + DR +R E R RDR++D ++R+ E D R+
Sbjct: 382 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREETRGKRDREKDTREERESEHDHRD 441
Query: 116 KEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRE--RERE 173
+ R+ R+R ++R R R S R+ R+ +E SRS RD R+RE
Sbjct: 442 DREPRDSRDRRDTRDRRELRDSRDMRDSREMRDYSRDAKESRDPRDSRSARDVHDYRDRE 501
Query: 174 ERDRSRRSRSRSERDFEMRDSR 195
RD R + + RD+R
Sbjct: 502 ARDAHARDVRDARDARDARDAR 523
Score = 65.9 bits (159), Expect = 6e-10
Identities = 68/223 (30%), Positives = 94/223 (41%), Gaps = 53/223 (23%)
Query: 21 SKKNESSDKTERSYRKRDE--------IEDGTEEKR-SKRRSSGDGDDE----------R 61
S N S D + +R R E +ED K ++RSS G + R
Sbjct: 1213 SNTNGSEDSHRKCHRARGEKVEVSHVTLEDTPHRKLVDQKRSSSLGSNRSHRSHTSGRLR 1272
Query: 62 VSKKD---RDRDDDRDKER--HRSGRDRDRDRDRD--GERSSR-DRDRDREKDRDREKDR 113
D R DD ++R H RDR++ + + GER SR D+ + E R DR
Sbjct: 1273 SPSNDSAHRSGDDQGSRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDR 1332
Query: 114 REKEKERERR-----------------------ERER-EKERERERSRRSKSRSERDREI 149
++ RR ER+R E +RERER RR + E DRE
Sbjct: 1333 QDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERDRRDPRQREWDREA 1392
Query: 150 ERE-ERERSRRSISRSERDRERERE-ERDRSRRSRSRSERDFE 190
E+E R R R + +RDR+R R+ +R+R R ERD E
Sbjct: 1393 EKEWPRTRDRDRLRERDRDRDRRRDLDRERERLISDPMERDRE 1435
Score = 65.5 bits (158), Expect = 8e-10
Identities = 49/174 (28%), Positives = 82/174 (46%), Gaps = 13/174 (7%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKE 76
+ + SS +++R R D + + + R D + ER + R R+ DR+ E
Sbjct: 1334 DSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERDRRDPRQREWDREAE 1393
Query: 77 RH-RSGRDRDRDRDRDGERSSR---DRDRDR----EKDRDREKDRREKEKERERRERERE 128
+ RDRDR R+RD +R R DR+R+R +RDRE++R + + E +R
Sbjct: 1394 KEWPRTRDRDRLRERDRDRDRRRDLDRERERLISDPMERDRERERTFETSQLESGKRSEV 1453
Query: 129 K-ERERERSRRSKSRSERDREIEREERE----RSRRSISRSERDREREREERDR 177
K E E ER SR + ER +R+ + +S++ER E ++ +
Sbjct: 1454 KLESEHERDLEGSSRDSVALDKERMDRDLGSVQGFEDVSKAERTESLEGDDESK 1507
Score = 64.3 bits (155), Expect = 2e-09
Identities = 46/152 (30%), Positives = 68/152 (44%), Gaps = 5/152 (3%)
Query: 48 RSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDR 107
RS R G D ER S+ R + R++ R + R++D +R+ E RD DR+ R
Sbjct: 391 RSPMREKGRHDHERTSQSHDRRHERREETRGKRDREKDTREERESEHDHRD-DREPRDSR 449
Query: 108 DRE--KDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSI-SRS 164
DR +DRRE R+ R+ ++ R+ R R + R+R R +R
Sbjct: 450 DRRDTRDRRELRDSRDMRDSREMRDYSRDAKESRDPRDSRSARDVHDYRDREARDAHARD 509
Query: 165 ERDREREREERDRSRRSRSRSERDF-EMRDSR 195
RD R+ RD R RD ++RD R
Sbjct: 510 VRDARDARDARDARDIRDVRDVRDVRDVRDVR 541
Score = 62.0 bits (149), Expect = 9e-09
Identities = 55/174 (31%), Positives = 84/174 (47%), Gaps = 10/174 (5%)
Query: 28 DKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRD-DDRDKERHRSGRDRDR 86
+K + + + D E+R + R G D E+ ++++R+ + D RD R RDR
Sbjct: 396 EKGRHDHERTSQSHDRRHERREETR--GKRDREKDTREERESEHDHRDDREPRDSRDRRD 453
Query: 87 DRDRDGERSSRDRDRDREKDRDREKDRREKEKERERRE-REREKERERERSRRSKSRSER 145
RDR R SRD RD + RD +D +E R+ R R+ R+RE +R + +R R
Sbjct: 454 TRDRRELRDSRDM-RDSREMRDYSRDAKESRDPRDSRSARDVHDYRDRE-ARDAHARDVR 511
Query: 146 DREIEREERE-RSRRSIS--RSERDREREREERDRSRRSRSRSERDF-EMRDSR 195
D R+ R+ R R + R RD R+ RD R RD ++RD+R
Sbjct: 512 DARDARDARDARDIRDVRDVRDVRDVRDVRDVRDVRDVRDVRDARDVRDVRDAR 565
Score = 60.5 bits (145), Expect = 3e-08
Identities = 58/188 (30%), Positives = 80/188 (41%), Gaps = 14/188 (7%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
EK + E + ++ E + KRD +D EE R S D D+R + RDR
Sbjct: 396 EKGRHDHERTSQSHDRRHERREETRGKRDREKDTREE----RESEHDHRDDREPRDSRDR 451
Query: 70 DDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREK 129
D RD+ R RD RD R RD RD ++ RD +D R + R+RE
Sbjct: 452 RDTRDRRELRDSRDM-RD-----SREMRDYSRDAKESRD-PRDSRSARDVHDYRDREARD 504
Query: 130 ERERERSRRSKSRSERDREIEREERE-RSRRSISRSERDREREREERDRSRRSRSRSERD 188
R+ +R RD R+ R+ R R + R RD R+ RD R RD
Sbjct: 505 AHARDVRDARDARDARDARDIRDVRDVRDVRDV-RDVRDVRDVRDVRDVRDARDVRDVRD 563
Query: 189 F-EMRDSR 195
++RD R
Sbjct: 564 ARDVRDVR 571
Score = 60.5 bits (145), Expect = 3e-08
Identities = 55/173 (31%), Positives = 74/173 (41%), Gaps = 9/173 (5%)
Query: 31 ERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKD-RDRDDDRDKERHRSGRDRDR--- 86
ER+ + D + EE R KR D +ER S+ D RD + RD R RDR
Sbjct: 403 ERTSQSHDRRHERREETRGKRDREKDTREERESEHDHRDDREPRDSRDRRDTRDRRELRD 462
Query: 87 DRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSERD 146
RD R RD RD ++ RD +D R + R+RE R+ +R RD
Sbjct: 463 SRDMRDSREMRDYSRDAKESRD-PRDSRSARDVHDYRDREARDAHARDVRDARDARDARD 521
Query: 147 REIEREERE-RSRRSIS--RSERDREREREERDRSRRSRSRSERDF-EMRDSR 195
R+ R+ R R + R RD R+ RD R RD ++RD R
Sbjct: 522 ARDIRDVRDVRDVRDVRDVRDVRDVRDVRDVRDARDVRDVRDARDVRDVRDVR 574
Score = 56.2 bits (134), Expect = 5e-07
Identities = 55/176 (31%), Positives = 77/176 (43%), Gaps = 15/176 (8%)
Query: 26 SSDKTERSYRKRDEIE---DGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGR 82
+S +R + +R+E D ++ R +R S D D+R + RDR D RD+ R R
Sbjct: 405 TSQSHDRRHERREETRGKRDREKDTREERESEHDHRDDREPRDSRDRRDTRDRRELRDSR 464
Query: 83 D-RD----RDRDRDGERSSRDRD----RDREKDRDRE-KDRREKEKERERREREREKERE 132
D RD RD RD + S RD RD RDRE +D ++ R R+ R+
Sbjct: 465 DMRDSREMRDYSRDAKESRDPRDSRSARDVHDYRDREARDAHARDVRDARDARDARDARD 524
Query: 133 RERSRRSKS-RSERDREIEREERERSRRSISRSERDREREREERD-RSRRSRSRSE 186
R + R RD R+ R+ +R RD R+ RD R R R E
Sbjct: 525 IRDVRDVRDVRDVRDVRDVRDVRDVRDVRDARDVRDVRDARDVRDVRDVRDGHRKE 580
Score = 53.5 bits (127), Expect = 3e-06
Identities = 50/217 (23%), Positives = 82/217 (37%), Gaps = 33/217 (15%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVS 63
+E E + E E + ++ E + ER + E E E +R DD R
Sbjct: 818 EERERERERERERERERERERERERERERERERAREREKERERQREWEDKDKGRDDRREK 877
Query: 64 KKD---RDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRD---REKDRREKE 117
++D R+ RD R + R R+ R S R R+ D D D+ EK
Sbjct: 878 REDIHVREDRIPRDSHEERKSKKRYRNEGSPSPRQSPKRRREHSPDSDTYHSGDDKNEKH 937
Query: 118 K---------------------ERERREREREKERERERSRRSKSRSERDREIEREERER 156
+ +R+ R +E +++ ER+ S R E ++ +R+R
Sbjct: 938 RLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKSERKESSRRYEEQELKEKLSCGDRQR 997
Query: 157 SRRSISRSERDR------EREREERDRSRRSRSRSER 187
+ S R R R+ E+RDR R+ E+
Sbjct: 998 EQAESVDSSRVRAQDLLSHRQAEDRDRDGSDRAHDEK 1034
Score = 47.8 bits (112), Expect = 2e-04
Identities = 60/253 (23%), Positives = 97/253 (37%), Gaps = 66/253 (26%)
Query: 9 LEKTVEELEDKDSKKNESSDKTERSYR-------KRDEIEDGTEEKRSKRRSSGDG---- 57
L K+ + + K S K S+ K ER + G + K+ R+
Sbjct: 212 LRKSSKSPKRKSSPKASSAGKKERKAAVVASPLLDQQRNSKGNQSKKKGPRTPSPPPPIL 271
Query: 58 DDERVSKKDRDRDD--DRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRR- 114
+D + KK +++ DR +E+ R G+DR RD ++ E+ + R + R
Sbjct: 272 EDIILGKKYKEKYKVKDRIEEKPRDGKDRGRDFEKQREKRDKPRSSSPGQHHSPLSSRHH 331
Query: 115 ----------EKEKERERRER-----------------------------EREKERERER 135
++ RR+R +R++ R R
Sbjct: 332 SSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPSLRRSASPYPTHCLSSPQRKQSPPRHR 391
Query: 136 S-RRSKSRSERDREIEREERERSRRSISRSERDRERE-REERDRSRRSR-------SRSE 186
S R K R + +R + +R RR +R +RDRE++ REER+ R SR
Sbjct: 392 SPMREKGRHDHERTSQSHDRRHERREETRGKRDREKDTREERESEHDHRDDREPRDSRDR 451
Query: 187 RDF----EMRDSR 195
RD E+RDSR
Sbjct: 452 RDTRDRRELRDSR 464
Score = 45.4 bits (106), Expect = 9e-04
Identities = 37/169 (21%), Positives = 74/169 (42%), Gaps = 10/169 (5%)
Query: 19 KDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERH 78
++S+ S TE + E + +E K S RR E++S DR R+ +
Sbjct: 947 QESRSLSPSHLTEDRQGRWKEEDRKSERKESSRRYEEQELKEKLSCGDRQREQAESVDSS 1006
Query: 79 RSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRR 138
R R +D R + DRDRD DR D EK+K + ++ ++K+ E R
Sbjct: 1007 RV-----RAQDLLSHRQAEDRDRD---GSDRAHD--EKKKAKAPKKPVKKKKEEDVGVER 1056
Query: 139 SKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSER 187
+ D ++ ++ + +++I + + + + + D +++ +R
Sbjct: 1057 GNLETHEDSQVFSPKKGQKKKNIEKKRKRSKGDSDVSDEEAAPQNKKKR 1105
Score = 44.3 bits (103), Expect = 0.002
Identities = 40/159 (25%), Positives = 65/159 (40%), Gaps = 13/159 (8%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKE 76
ED+ + E K+ER R E +EK S GD E+ D R +D
Sbjct: 959 EDRQGRWKEEDRKSERKESSRRYEEQELKEKLS----CGDRQREQAESVDSSRVRAQDLL 1014
Query: 77 RHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERS 136
HR DRD RD DR D +K K +K+KE + E +
Sbjct: 1015 SHRQAEDRD--RD------GSDRAHDEKKKAKAPKKPVKKKKEEDVGVERGNLETHEDSQ 1066
Query: 137 RRSKSRSERDREIEREERERSRRSISRSERDREREREER 175
S + ++ + IE+ +R+RS+ S+ + + +++
Sbjct: 1067 VFSPKKGQKKKNIEK-KRKRSKGDSDVSDEEAAPQNKKK 1104
Score = 38.5 bits (88), Expect = 0.11
Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 14/129 (10%)
Query: 47 KRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKD 106
+RS R +GD ER+ K +D D + K R+ + S ++ R +
Sbjct: 75 RRSPERPTGDLR-ERMKNKRQDVDSESQK------------RNTEEPSSPVRKESSRGRH 121
Query: 107 RDREKDRREKEKERERREREREKERERERSRRSKSRSERDREIERE-ERERSRRSISRSE 165
RD+E + KE+ E E E E R+ S + E+ E +R++ +R + + E
Sbjct: 122 RDKEDIKIVKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLE 181
Query: 166 RDREREREE 174
++ +REE
Sbjct: 182 QENMDKREE 190
Score = 37.7 bits (86), Expect = 0.18
Identities = 35/149 (23%), Positives = 66/149 (43%), Gaps = 33/149 (22%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDR 73
+ L+++D +++ + +R ++ E + E++ + R D +R+ ++DRDRD R
Sbjct: 1362 DRLQERDRYEHDRERERDRRDPRQREWDREAEKEWPRTR-----DRDRLRERDRDRDRRR 1416
Query: 74 DKERHRSG-------RDRDRDR---------------------DRDGERSSRDRDRDREK 105
D +R R RDR+R+R +RD E SSRD ++
Sbjct: 1417 DLDRERERLISDPMERDRERERTFETSQLESGKRSEVKLESEHERDLEGSSRDSVALDKE 1476
Query: 106 DRDREKDRREKEKERERREREREKERERE 134
DR+ + ++ + ER E + E
Sbjct: 1477 RMDRDLGSVQGFEDVSKAERTESLEGDDE 1505
Score = 35.8 bits (81), Expect = 0.68
Identities = 46/198 (23%), Positives = 76/198 (38%), Gaps = 27/198 (13%)
Query: 6 YEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEI----EDGTEEKRSKR------RSSG 55
Y+Y+ + E++ + + E + + KR+EI E E RSK R S
Sbjct: 158 YDYVHELSLEMK-RQKIQRELMKLEQENMDKREEIIIQKEVSPEVVRSKLSPSPSLRKSS 216
Query: 56 DGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRD------------- 102
+ S K K + D+ R+ G +S + R
Sbjct: 217 KSPKRKSSPKASSAGKKERKAAVVASPLLDQQRNSKGNQSKKKGPRTPSPPPPILEDIIL 276
Query: 103 --REKDRDREKDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRS 160
+ K++ + KDR E EK R+ ++R R+ E++RE+ + +S S R S S
Sbjct: 277 GKKYKEKYKVKDRIE-EKPRDGKDRGRDFEKQREKRDKPRSSSPGQHHSPLSSRHHSSSS 335
Query: 161 ISRSERDREREREERDRS 178
S S R R R+
Sbjct: 336 QSGSSIQRHSPSPRRKRT 353
Score = 34.7 bits (78), Expect = 1.5
Identities = 35/168 (20%), Positives = 77/168 (45%), Gaps = 27/168 (16%)
Query: 21 SKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRS 80
S + + D ER KR +++ ++++ ++ SS +K+ R RDKE +
Sbjct: 77 SPERPTGDLRERMKNKRQDVDSESQKRNTEEPSSP-------VRKESSRGRHRDKEDIKI 129
Query: 81 GRDRDRDRDRDGERSSRDRD------------RDREKDRDREKDRRE----KEKERERRE 124
++R + + + +RD + + R+K +RE +++ ++RE
Sbjct: 130 VKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMDKRE 189
Query: 125 R---EREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRE 169
++E E RS+ S S S R + + +R+ S ++ S +++R+
Sbjct: 190 EIIIQKEVSPEVVRSKLSPSPSLR-KSSKSPKRKSSPKASSAGKKERK 236
>ref|XP_612879.1| PREDICTED: similar to KIAA0853, partial [Bos taurus]
Length = 709
Score = 136 bits (342), Expect = 4e-31
Identities = 85/191 (44%), Positives = 126/191 (65%), Gaps = 21/191 (10%)
Query: 18 DKDSKKNESSDKTE----RSYRKRDEIEDGTEEKRSKRR--SSGDGDDERVSKKDRDRDD 71
++D + N D+ R + DE+E +E+R +RR + D DER ++DR+R+
Sbjct: 516 ERDRRDNRERDQRPSSPIRHQGRNDELE--RDERREERRVDRTDDRRDERARERDRERER 573
Query: 72 DRDKERHRSGRDRDRDRDRDGERS----SRDRDRDREKDRDREKDR-REKEKERER-RER 125
+R++ER R RDR+R+++R+ ER R+R+R+REK+RDRE++R RE ++ERER RER
Sbjct: 574 ERERERERE-RDREREKERELERERAAREREREREREKERDRERERDREHDRERERERER 632
Query: 126 EREKERERERSRRSKSRSERDREIERE-ERERSRRSISRSERDREREREERDRSRRSRSR 184
EREKERERER R + R ER+RE ERE ERER+R ER+RER+RE D+ + R
Sbjct: 633 EREKEREREREERERER-ERERERERERERERAR----ERERERERQREWEDKEKAREDR 687
Query: 185 SERDFEMRDSR 195
E+ ++R+ R
Sbjct: 688 REKREDLREDR 698
Score = 129 bits (325), Expect = 3e-29
Identities = 83/185 (44%), Positives = 115/185 (61%), Gaps = 12/185 (6%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKR--SKRRSSGDGD----DERVSKKDRDRDD 71
++D+++ ER + +RD ++ ++R S R G D DER ++ DR D
Sbjct: 498 ERDNREQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRTD 557
Query: 72 DRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKER 131
DR ER R RDR+R+R+R+ ER R+RDR+REK+R+ E++R +E+ERER ERE+E++R
Sbjct: 558 DRRDERARE-RDRERERERERERE-RERDREREKERELERERAARERERER-EREKERDR 614
Query: 132 ERERSRRSKSRSERDREIERE-ERERSRRSISRS-ERDRERERE-ERDRSRRSRSRSERD 188
ERER R ER+RE ERE ERER R R ER+RERERE ER+R+R ER
Sbjct: 615 ERERDREHDREREREREREREKEREREREERERERERERERERERERERARERERERERQ 674
Query: 189 FEMRD 193
E D
Sbjct: 675 REWED 679
Score = 129 bits (323), Expect = 6e-29
Identities = 71/168 (42%), Positives = 106/168 (62%), Gaps = 9/168 (5%)
Query: 27 SDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKE------RHRS 80
+D+ ER R+ + D T+++R +R D + ER +++R+R+ DR++E R R+
Sbjct: 539 NDELERDERREERRVDRTDDRRDERARERDRERERERERERERERDREREKERELERERA 598
Query: 81 GRDRDRDRDRDGERSSRDRDRDREKDRDREKDR-REKEKERERREREREKERERERSRRS 139
R+R+R+R+R+ ER R+R+RDRE DR+RE++R RE+EKERER ERE+ERERER R
Sbjct: 599 AREREREREREKERD-RERERDREHDREREREREREREKEREREREERERERERERERER 657
Query: 140 KSRSERDREIERE-ERERSRRSISRSERDREREREERDRSRRSRSRSE 186
+ ER RE ERE ER+R ++ DR +RE+ R R E
Sbjct: 658 ERERERARERERERERQREWEDKEKAREDRREKREDLREDRNPRDGHE 705
Score = 112 bits (279), Expect = 8e-24
Identities = 74/196 (37%), Positives = 104/196 (52%), Gaps = 15/196 (7%)
Query: 15 ELEDKDSKKN-ESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDR 73
+++ S N S +T SY +RD + ++++ S ER + +R+RD
Sbjct: 470 QIDSHSSSSNYHDSWETRSSYPERDRYPERDNREQARDSSFERRHGERDRRDNRERDQRP 529
Query: 74 DKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR---REKEKERER-REREREK 129
GR+ + +RD E DR DR +R RE+DR RE+E+ERER R+REREK
Sbjct: 530 SSPIRHQGRNDELERDERREERRVDRTDDRRDERARERDRERERERERERERERDREREK 589
Query: 130 ERERERSRRSKSR-------SERDREIERE---ERERSRRSISRSERDREREREERDRSR 179
ERE ER R ++ R ERDRE ER+ +RER R E++REREREER+R R
Sbjct: 590 ERELERERAAREREREREREKERDRERERDREHDREREREREREREKEREREREERERER 649
Query: 180 RSRSRSERDFEMRDSR 195
ER+ E +R
Sbjct: 650 ERERERERERERERAR 665
Score = 98.6 bits (244), Expect = 9e-20
Identities = 60/173 (34%), Positives = 102/173 (58%), Gaps = 23/173 (13%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKR-----RSSGDGDDERVSK 64
E+ V+ +D+ ++ D+ R+R+ + E+ +R R++ + + ER +
Sbjct: 550 ERRVDRTDDRRDERARERDRERERERERERERERDREREKERELERERAARERERERERE 609
Query: 65 KDRDRDDDRDKERHRSG---RDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERE 121
K+RDR+ +RD+E R R+R+R+++R+ ER R+R+R+RE++ RE+E+ERE
Sbjct: 610 KERDRERERDREHDREREREREREREKEREREREERERERERERE-------RERERERE 662
Query: 122 R-REREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE 173
R RERERE+ER+RE + K+R +R RE+RE R R+ RD ER+
Sbjct: 663 RARERERERERQREWEDKEKAREDR-----REKREDLRE--DRNPRDGHEERK 708
Score = 82.8 bits (203), Expect = 5e-15
Identities = 65/200 (32%), Positives = 93/200 (46%), Gaps = 12/200 (6%)
Query: 8 YLEKTVEELEDKDSKKNES-----SDKTERSYRKRDEI-EDGTEEKR-SKRRSSGDGDDE 60
+L + E ++ +NES +D+ RS + E+ E G+ R S+ S +
Sbjct: 421 HLREESSRAEIRNDSRNESRSEIRNDRMGRSRGRAPEMPEKGSRGTRGSQIDSHSSSSNY 480
Query: 61 RVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEK-- 118
S + R +RD+ R R++ RD + RDR +RE+D+ R + +
Sbjct: 481 HDSWETRSSYPERDRYPERDNREQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRND 540
Query: 119 ERERREREREKERERERSRRSKSRSERDREIERE---ERERSRRSISRSERDREREREER 175
E ER ER E+ +R RR + ERDRE ERE ERER R ER+ ERER R
Sbjct: 541 ELERDERREERRVDRTDDRRDERARERDRERERERERERERERDREREKERELERERAAR 600
Query: 176 DRSRRSRSRSERDFEMRDSR 195
+R R ERD E R
Sbjct: 601 EREREREREKERDRERERDR 620
Score = 75.5 bits (184), Expect = 8e-13
Identities = 42/136 (30%), Positives = 79/136 (57%), Gaps = 6/136 (4%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
E+ E D++ +K ++ ER+ R+R+ + +E+ +R + D ER +++R+R
Sbjct: 576 ERERERERDREREKERELER-ERAAREREREREREKERDRERERDREHDRERERERERER 634
Query: 70 DDDRDKERHRSGRDRDRDRD----RDGERSSRDRDRDREKDRDREKDRREKEKERERRER 125
+ +R++ER R+R+R+R+ R+ ER +R+R+R+RE+ R+ E + +E RE+RE
Sbjct: 635 EKEREREREERERERERERERERERERER-ARERERERERQREWEDKEKAREDRREKRED 693
Query: 126 EREKERERERSRRSKS 141
RE R+ KS
Sbjct: 694 LREDRNPRDGHEERKS 709
Score = 72.0 bits (175), Expect = 9e-12
Identities = 69/223 (30%), Positives = 99/223 (43%), Gaps = 39/223 (17%)
Query: 7 EYLEKTVEELEDKDSKKN-ESSDKTERSYRKRDEIEDG-TEEKRSKRRSSGDGDDERVSK 64
+Y E + +DS+ ++ D +R R ED EE RS R+ + R
Sbjct: 372 DYSRDNKESRDPRDSRSTRDAHDYRDRESRDAHRKEDAYQEESRSYGRNHLREESSRAEI 431
Query: 65 KDRDRDDDRDKERH-RSGRDRDR--DRDRDGERSSRDRDRDR------------------ 103
++ R++ R + R+ R GR R R + G R +R D
Sbjct: 432 RNDSRNESRSEIRNDRMGRSRGRAPEMPEKGSRGTRGSQIDSHSSSSNYHDSWETRSSYP 491
Query: 104 EKDRDREKDRREKEKER--ERREREREKERERERSRRSKS---RSERDREIEREERE--- 155
E+DR E+D RE+ ++ ERR ER++ RER +R S R+ E+ER+ER
Sbjct: 492 ERDRYPERDNREQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 551
Query: 156 R-----SRRSISRSERDRERERE---ERDRSRRSRSRSERDFE 190
R RR ERDRERERE ER+R R ER+ E
Sbjct: 552 RVDRTDDRRDERARERDRERERERERERERERDREREKERELE 594
Score = 70.5 bits (171), Expect = 3e-11
Identities = 54/178 (30%), Positives = 77/178 (42%), Gaps = 9/178 (5%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKR--RSSGDGDDERVSKKDR 67
EK + E + ++ E + KRD +D EE+ ++ SS D D+R + R
Sbjct: 285 EKGRHDHERASQSHDRRHERREETRGKRDREKDTREEREYEQDQSSSRDHRDDREPRDGR 344
Query: 68 DRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERRERER 127
DR D RD R RD RD R RD RD ++ RD +D R + R+RE
Sbjct: 345 DRRDARDTRDRRELRD---SRDVRDSREMRDYSRDNKESRD-PRDSRSTRDAHDYRDRES 400
Query: 128 EKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRS 185
+E + + +SRS + E SR I R+ R DR RSR R+
Sbjct: 401 RDAHRKEDAYQEESRSYGRNHLREES---SRAEIRNDSRNESRSEIRNDRMGRSRGRA 455
Score = 62.4 bits (150), Expect = 7e-09
Identities = 57/168 (33%), Positives = 83/168 (48%), Gaps = 20/168 (11%)
Query: 48 RSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGER---SSRDRDRDRE 104
RS R G D ER S+ R + R++ R + R++D +R+ E+ SSRD DRE
Sbjct: 280 RSPVREKGRHDHERASQSHDRRHERREETRGKRDREKDTREEREYEQDQSSSRDHRDDRE 339
Query: 105 K--DRDRE-----KDRREKEKERERRERE--REKERERERSRRSK-SRSERDRE--IERE 152
RDR +DRRE R+ R+ R+ R+ + SR + SRS RD +RE
Sbjct: 340 PRDGRDRRDARDTRDRRELRDSRDVRDSREMRDYSRDNKESRDPRDSRSTRDAHDYRDRE 399
Query: 153 ERERSRRSISRSERD----REREREERDRSR-RSRSRSERDFEMRDSR 195
R+ R+ + E R REE R+ R+ SR+E E+R+ R
Sbjct: 400 SRDAHRKEDAYQEESRSYGRNHLREESSRAEIRNDSRNESRSEIRNDR 447
Score = 60.8 bits (146), Expect = 2e-08
Identities = 43/140 (30%), Positives = 65/140 (45%), Gaps = 12/140 (8%)
Query: 60 ERVSKKDRDRDDDRDKERH---RSGRDRDRDRDRDGE-RSSRDRDRDREKDRDREKDRRE 115
+R R R R+K RH R+ + DR +R E R RDR++D ++R+ E+D+
Sbjct: 271 QRKQSPPRHRSPVREKGRHDHERASQSHDRRHERREETRGKRDREKDTREEREYEQDQSS 330
Query: 116 KEKERERREREREKERERERSRRSKSRSERDREIEREERE-RSRRSISRSERDREREREE 174
R+ RE R+ R +R RDR R+ R+ R R + RD + R+
Sbjct: 331 SRDHRDDRE-------PRDGRDRRDARDTRDRRELRDSRDVRDSREMRDYSRDNKESRDP 383
Query: 175 RDRSRRSRSRSERDFEMRDS 194
RD + RD E RD+
Sbjct: 384 RDSRSTRDAHDYRDRESRDA 403
Score = 60.1 bits (144), Expect = 3e-08
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 12/169 (7%)
Query: 31 ERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKER-HRSGRDRDRDRD 89
ER+ + D + EE R KR D E+ ++++R+ + D+ R HR R+ RD
Sbjct: 292 ERASQSHDRRHERREETRGKR------DREKDTREEREYEQDQSSSRDHRDDREPRDGRD 345
Query: 90 RDGERSSRDRDRDREKDRDREKDRRE-KEKERERRE-REREKERERERSRRSKSRSERDR 147
R R +RDR R+ RD +D RE ++ R+ +E R+ R + + R RD
Sbjct: 346 RRDARDTRDR-RELRDSRD-VRDSREMRDYSRDNKESRDPRDSRSTRDAHDYRDRESRDA 403
Query: 148 EIEREERERSRRSISRSERDREREREERDRSRRSRSRSE-RDFEMRDSR 195
+ + + RS R+ E R E R+ SRSE R+ M SR
Sbjct: 404 HRKEDAYQEESRSYGRNHLREESSRAEIRNDSRNESRSEIRNDRMGRSR 452
Score = 48.5 bits (114), Expect = 1e-04
Identities = 59/242 (24%), Positives = 96/242 (39%), Gaps = 69/242 (28%)
Query: 21 SKKNESSDKTERSYRKRDE---------IEDGTEEKRSKRRSSGDG---------DDERV 62
S K +SS K+ S K+D ++ K ++ + G +D +
Sbjct: 105 SPKRKSSPKSSSSTSKKDRKTTAVSSPLLDQQRNSKSNQSKKKGPRTPSPPPPIQEDIAL 164
Query: 63 SKKDRDRDD--DRDKERHRSGRDRDRDRDRDGERSSRDRDRD--------------REKD 106
KK +++ DR +E+ R G+DR RD +R +R RD+ R
Sbjct: 165 GKKYKEKYKLKDRIEEKPRDGKDRGRDFER--QREKRDKPRSTSPAGQHHSPISSRHHSS 222
Query: 107 RDREKDRREKEKERERRER-----------------------------EREKERERERSR 137
+ ++ RR+R +R++ R RS
Sbjct: 223 SSQSGSSIQRHSPSPRRKRTPSPSYQRTITPPLRRSASPYPSHSLASPQRKQSPPRHRSP 282
Query: 138 -RSKSRSERDREIEREERERSRRSISRSERDRERE-REERDRSR-RSRSRSER-DFEMRD 193
R K R + +R + +R RR +R +RDRE++ REER+ + +S SR R D E RD
Sbjct: 283 VREKGRHDHERASQSHDRRHERREETRGKRDREKDTREEREYEQDQSSSRDHRDDREPRD 342
Query: 194 SR 195
R
Sbjct: 343 GR 344
Score = 42.4 bits (98), Expect = 0.007
Identities = 31/117 (26%), Positives = 55/117 (46%), Gaps = 29/117 (24%)
Query: 7 EYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKD 66
E+ + E E + K+ E R+R+E ER +++
Sbjct: 621 EHDREREREREREREKERE---------REREE-------------------RERERERE 652
Query: 67 RDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERR 123
R+R+ +R++ER R R+R+R+R R+ E + R+ REK D +DR ++ ER+
Sbjct: 653 RERERERERERARE-RERERERQREWEDKEKAREDRREKREDLREDRNPRDGHEERK 708
Score = 33.5 bits (75), Expect = 3.4
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 16/151 (10%)
Query: 47 KRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKD 106
K S R + +D +++K +R + + + + RD D D + D + +
Sbjct: 1 KESSRGRHREKEDIKITK-ERTPESEEENVEWETNRD-----DSDNGDINYDYVHELSLE 54
Query: 107 RDREKDRRE----KEKERERRER---EREKERERERSRRSKSRSERDREIEREERERSRR 159
R+K +RE +++ E+RE ++E E RS+ S S S R + + +
Sbjct: 55 MKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKS 114
Query: 160 SISRSERDREREREER---DRSRRSRSRSER 187
S S S++DR+ D+ R S+S +
Sbjct: 115 SSSTSKKDRKTTAVSSPLLDQQRNSKSNQSK 145
>gb|AAH84352.1| LOC495149 protein [Xenopus laevis]
Length = 1029
Score = 134 bits (338), Expect = 1e-30
Identities = 79/184 (42%), Positives = 118/184 (63%), Gaps = 14/184 (7%)
Query: 19 KDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERH 78
+D +++ R + D+ E EE+R +RR D DER ++ R+R+ ++++ER
Sbjct: 676 RDRDRDQRPTSPVRHQGRNDDTE--REERREERRV--DRTDERRDERAREREREKERERE 731
Query: 79 RSGRDRDRDRDRDGERS-SRDRDRDREKDRDREKDRREKEKERERREREREKERERERSR 137
R R+R+R+++R+ ER +R+RDR+RE+++DRE++R EKE+ERER ERERE+ERERER R
Sbjct: 732 REQREREREKERESERERARERDREREREKDRERER-EKEREREREERERERERERERER 790
Query: 138 RSKSRSERDREIEREERERSRRSISRSERDRERER------EERDRSRRSRSRSERDFEM 191
ER+RE ER ERER R ER RER+R EE++++R R R +RD
Sbjct: 791 ERDRERERERERER-ERERDREKEKERERGRERDRDRPRDWEEKEKAREDR-RDKRDDVR 848
Query: 192 RDSR 195
D R
Sbjct: 849 EDKR 852
Score = 119 bits (299), Expect = 4e-26
Identities = 71/186 (38%), Positives = 114/186 (61%), Gaps = 10/186 (5%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDD-ERVSKKDRDRDDD 72
+ +++D ++ S D+ +RD D + S R G DD ER +++ R D
Sbjct: 653 DRYDNRDQGRDSSFDRRHGDRDRRDRDRD--QRPTSPVRHQGRNDDTEREERREERRVDR 710
Query: 73 RDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERER-REREREKER 131
D+ R R+R+R+++R+ ER R+R+R++E++ +RE+ RE+++ERER ++RERE+E+
Sbjct: 711 TDERRDERAREREREKEREREREQREREREKERESERER-ARERDREREREKDREREREK 769
Query: 132 ERERSRRSKSRSERDREIERE-ERERSRRSISRSERDRERERE---ERDRSRRSRSRSER 187
ERER R + R ER+RE ERE ER+R R ER+RER+RE ER+R R R
Sbjct: 770 EREREREERER-ERERERERERERDRERERERERERERERDREKEKERERGRERDRDRPR 828
Query: 188 DFEMRD 193
D+E ++
Sbjct: 829 DWEEKE 834
Score = 119 bits (299), Expect = 4e-26
Identities = 73/180 (40%), Positives = 106/180 (58%), Gaps = 14/180 (7%)
Query: 20 DSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGD-DERVSK--KDRDRDDDRDKE 76
D+ ++ SS Y RD+ D + ++R R D D D+R + + + R+DD ++E
Sbjct: 641 DNWESRSSYTERDRYDNRDQGRDSSFDRRHGDRDRRDRDRDQRPTSPVRHQGRNDDTERE 700
Query: 77 RHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERER-----REREREKER 131
R R DR +R ER+ R+R+REK+R+RE+++RE+E+E+ER R RER++ER
Sbjct: 701 ERREERRVDRTDERRDERA---REREREKEREREREQREREREKERESERERARERDRER 757
Query: 132 ERERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE---ERDRSRRSRSRSERD 188
ERE+ R + ER+RE E ERER R ERDRERERE ER+R R ER+
Sbjct: 758 EREKDREREREKEREREREERERERERERERERERDRERERERERERERERDREKEKERE 817
Score = 116 bits (290), Expect = 4e-25
Identities = 68/177 (38%), Positives = 117/177 (65%), Gaps = 10/177 (5%)
Query: 14 EELEDKDSKKNESSDKT-ERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDD 72
++ E ++ ++ D+T ER + E E E +R + + + + ER S+++R R+ D
Sbjct: 695 DDTEREERREERRVDRTDERRDERAREREREKEREREREQREREREKERESERERARERD 754
Query: 73 RDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR-REKEKERER-REREREKE 130
R++ER + R+R+R+++R+ ER R+R+R+RE++R+RE+DR RE+E+ERER RER+REKE
Sbjct: 755 REREREKD-REREREKEREREREERERERERERERERERDRERERERERERERERDREKE 813
Query: 131 RERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSER 187
+ERER R +RDR + EE+E++R R +RD RE ++R+ + +SE+
Sbjct: 814 KERERGR----ERDRDRPRDWEEKEKARED-RRDKRDDVRE-DKRELHEDRKPKSEK 864
Score = 109 bits (272), Expect = 5e-23
Identities = 64/189 (33%), Positives = 112/189 (58%), Gaps = 17/189 (8%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKE 76
E +D + E + ER + + +E+ S+R + + D ER +KDR+R+ ++++E
Sbjct: 713 ERRDERAREREREKEREREREQREREREKERESERERARERDREREREKDREREREKERE 772
Query: 77 RHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR---REKEKERER-REREREKER- 131
R R R+R+R+R+R+ ER +RDR+RE++R+RE++R REKEKERER RER+R++ R
Sbjct: 773 REREERERERERERERER---ERDRERERERERERERERDREKEKERERGRERDRDRPRD 829
Query: 132 --ERERSRRSKSRSERD------REIEREERERSRRSISRSERDREREREERDRSRRSRS 183
E+E++R + R +RD RE+ + + +S + + ++ +++R R R S
Sbjct: 830 WEEKEKAREDR-RDKRDDVREDKRELHEDRKPKSEKGKIEGQINQNLHKDQRKRHRNESS 888
Query: 184 RSERDFEMR 192
S R R
Sbjct: 889 PSPRQSPKR 897
Score = 108 bits (270), Expect = 8e-23
Identities = 88/227 (38%), Positives = 113/227 (49%), Gaps = 46/227 (20%)
Query: 15 ELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSG----------DGDDERVSK 64
E + +N S + +RS R R D +E+ RSS D + R S
Sbjct: 590 ETRNDSRNENRSDTRNDRSGRARGRAPDPSEKTGRAARSSQADNHSSSNYHDNWESRSSY 649
Query: 65 KDRDRDDDRDKERH---------RSGRDRDRD-----------RDRDGERSSR------D 98
+RDR D+RD+ R R RDRDRD R+ D ER R D
Sbjct: 650 TERDRYDNRDQGRDSSFDRRHGDRDRRDRDRDQRPTSPVRHQGRNDDTEREERREERRVD 709
Query: 99 RDRDREKDRDREKDR---REKEKERERREREREKERERERSR-RSKSRS-ERDREIERE- 152
R +R +R RE++R RE+E+E+ RERE+E+E ERER+R R + R E+DRE ERE
Sbjct: 710 RTDERRDERAREREREKEREREREQREREREKERESERERARERDREREREKDREREREK 769
Query: 153 ERERSRRSISRS-ERDRERERE---ERDRSRRSRSRSERDFEMRDSR 195
ERER R R ER+RERERE ER+R R ERD E R
Sbjct: 770 EREREREERERERERERERERERDRERERERERERERERDREKEKER 816
Score = 100 bits (248), Expect = 3e-20
Identities = 59/174 (33%), Positives = 97/174 (54%), Gaps = 11/174 (6%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
E+ E+ E + K+ ES + R + E E E +R K R + ER +++R+R
Sbjct: 729 EREREQREREREKERESERERARERDREREREKDREREREKEREREREERERERERERER 788
Query: 70 DDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREK 129
+ +RD+ER R R+R+R+R+RD E+ ++R+R RE+DRDR +D EKEK RE R +R+
Sbjct: 789 ERERDRERERE-RERERERERDREKE-KERERGRERDRDRPRDWEEKEKAREDRRDKRDD 846
Query: 130 ERERER---------SRRSKSRSERDREIEREERERSRRSISRSERDREREREE 174
RE +R S + K + ++ + +++R+R R S S R + R E
Sbjct: 847 VREDKRELHEDRKPKSEKGKIEGQINQNLHKDQRKRHRNESSPSPRQSPKRRRE 900
Score = 89.7 bits (221), Expect = 4e-17
Identities = 79/255 (30%), Positives = 102/255 (39%), Gaps = 67/255 (26%)
Query: 4 DEYEYLEKTVEELEDKD------SKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDG 57
D +EY ++ E KD S +N D T R+ + + D E RS R+ G
Sbjct: 550 DTHEYRDRDNRESHRKDEQYDERSYRNHGRDDTSRAESRNETRNDSRNENRSDTRNDRSG 609
Query: 58 --------DDERVSKKDRDRDDDRDK--------ERHRSGRDRDRDRDRD-GERSSRDRD 100
E+ + R D E S +RDR +RD G SS DR
Sbjct: 610 RARGRAPDPSEKTGRAARSSQADNHSSSNYHDNWESRSSYTERDRYDNRDQGRDSSFDR- 668
Query: 101 RDREKDRDREK-------------------------------DRREKEKERERREREREK 129
R DRDR DR ++ ++ REREREK
Sbjct: 669 --RHGDRDRRDRDRDQRPTSPVRHQGRNDDTEREERREERRVDRTDERRDERAREREREK 726
Query: 130 ERERERSRRSKSRSERDREIERE---------ERERSRRSISRSERDREREREERDRSRR 180
ERERER +R + R E++RE ERE ERE+ R ER+RERE ER+R R
Sbjct: 727 EREREREQRERER-EKERESERERARERDREREREKDREREREKEREREREERERERERE 785
Query: 181 SRSRSERDFEMRDSR 195
ERD E R
Sbjct: 786 RERERERDRERERER 800
Score = 79.0 bits (193), Expect = 7e-14
Identities = 47/156 (30%), Positives = 74/156 (47%), Gaps = 1/156 (0%)
Query: 23 KNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGR 82
+ +S +RS+ +RDE ++ R SG DD R S++ RDR + RD HR R
Sbjct: 461 RERASASHDRSHERRDESRGRKRDRDHNREPSGSRDD-RESREGRDRREVRDNRDHREPR 519
Query: 83 DRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSR 142
D +R+ R RD R++ R + ++R+ RE R+ E+ ERS R+ R
Sbjct: 520 DSRDNRETRDSREYRDAKESRDQKDSRSTRDTHEYRDRDNRESHRKDEQYDERSYRNHGR 579
Query: 143 SERDREIEREERERSRRSISRSERDREREREERDRS 178
+ R R E R+ +RS+ +R R R+
Sbjct: 580 DDTSRAESRNETRNDSRNENRSDTRNDRSGRARGRA 615
Score = 77.8 bits (190), Expect = 2e-13
Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 37/222 (16%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
E+ E +++ +K+ ++ + R+R+E E E +R + R D + ER +++R+R
Sbjct: 748 ERARERDREREREKDREREREKEREREREERERERERERERERER-DRERERERERERER 806
Query: 70 DDDRDKERHRS-GRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERR----- 123
+ DR+KE+ R GR+RDRDR RD E + R+ R+K D +D+RE ++R+ +
Sbjct: 807 ERDREKEKERERGRERDRDRPRDWEEKEKAREDRRDKRDDVREDKRELHEDRKPKSEKGK 866
Query: 124 -----------------------------EREREKERERERSRRSKSRSERDREIEREER 154
+R RE + + ++E+ R + + +
Sbjct: 867 IEGQINQNLHKDQRKRHRNESSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVK 926
Query: 155 ERSRRSISRSERDREREREERDRSRRS-RSRSERDFEMRDSR 195
RS+S + ER ++ R+S R S R +E +++
Sbjct: 927 PLDSRSLSPAHVTEERPSRWKEEERKSERKESSRRYEESETK 968
Score = 68.9 bits (167), Expect = 7e-11
Identities = 58/153 (37%), Positives = 75/153 (48%), Gaps = 11/153 (7%)
Query: 48 RSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRD--RDRDREK 105
RS R G D ER S + RD+ R R RDRD +R+ G R R+ RDR +
Sbjct: 450 RSPTREKGRHDRERASASHDRSHERRDESRGRK-RDRDHNREPSGSRDDRESREGRDRRE 508
Query: 106 DRDREKDRREKEKERERRE-REREKERERERSRRSK-SRSERDREIEREERERSRRSISR 163
RD +D RE R+ RE R+ + R+ + SR K SRS RD E R+R R R
Sbjct: 509 VRD-NRDHREPRDSRDNRETRDSREYRDAKESRDQKDSRSTRD---THEYRDRDNRESHR 564
Query: 164 SERDREREREERDRSRRSRSRSERDFEMR-DSR 195
+ + ER R+ R SR+E E R DSR
Sbjct: 565 KDEQYD-ERSYRNHGRDDTSRAESRNETRNDSR 596
Score = 67.4 bits (163), Expect = 2e-10
Identities = 53/181 (29%), Positives = 76/181 (41%), Gaps = 10/181 (5%)
Query: 18 DKDSKKNESS---DKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRD 74
D+D + S D+ R R R E+ D + + R S D + R S++ RD + RD
Sbjct: 484 DRDHNREPSGSRDDRESREGRDRREVRDNRDHREP--RDSRDNRETRDSREYRDAKESRD 541
Query: 75 KERHRSGRDRDRDRDRDGERSSRDRDRDREKD-RDREKDRREKEKERERREREREKERER 133
++ RS RD RDRD S R +D + D R R+ E R R R
Sbjct: 542 QKDSRSTRDTHEYRDRDNRESHR---KDEQYDERSYRNHGRDDTSRAESRNETRNDSRNE 598
Query: 134 ERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSERD-FEMR 192
RS RS R R + E++ R+ S+ D D S +ERD ++ R
Sbjct: 599 NRSDTRNDRSGRARGRAPDPSEKTGRAARSSQADNHSSSNYHDNWESRSSYTERDRYDNR 658
Query: 193 D 193
D
Sbjct: 659 D 659
Score = 64.7 bits (156), Expect = 1e-09
Identities = 46/144 (31%), Positives = 67/144 (45%), Gaps = 17/144 (11%)
Query: 60 ERVSKKDRDRDDDRDKERH---RSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREK 116
+R + R R+K RH R+ DR +R E R RDRD ++ +D RE
Sbjct: 441 QRKRSPSKHRSPTREKGRHDRERASASHDRSHERRDESRGRKRDRDHNREPSGSRDDRES 500
Query: 117 EKERERRE-REREKERERERSRRSK----SRSERDREIEREERERSRRSISRSERDRERE 171
+ R+RRE R+ RE SR ++ SR RD + R++++ SRS RD
Sbjct: 501 REGRDRREVRDNRDHREPRDSRDNRETRDSREYRDAKESRDQKD------SRSTRD---T 551
Query: 172 REERDRSRRSRSRSERDFEMRDSR 195
E RDR R R + ++ R R
Sbjct: 552 HEYRDRDNRESHRKDEQYDERSYR 575
Score = 64.3 bits (155), Expect = 2e-09
Identities = 51/176 (28%), Positives = 79/176 (43%), Gaps = 6/176 (3%)
Query: 23 KNESSDKTERSYRK-RDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSG 81
+ SS + +RS K R + R + +S D ER + R R DRD R SG
Sbjct: 435 RTSSSPQRKRSPSKHRSPTREKGRHDRERASASHDRSHER-RDESRGRKRDRDHNREPSG 493
Query: 82 RDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRS-- 139
DR+ +R +RD + RD +D RE RE R+ + ++++ RS R
Sbjct: 494 SRDDRESREGRDRREVRDNRDHREPRD-SRDNRETRDSREYRDAKESRDQKDSRSTRDTH 552
Query: 140 KSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSERDFEMRDSR 195
+ R +RE R++ + RS RD E R+ +R SR+E + R+ R
Sbjct: 553 EYRDRDNRESHRKDEQYDERSYRNHGRDDTSRAESRNETRND-SRNENRSDTRNDR 607
Score = 58.5 bits (140), Expect = 1e-07
Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 19/187 (10%)
Query: 20 DSKKNESSDKTE----RSYRKRDEIEDGTEEKRSKR-RSSGDGDDERVSKKDRDRDDDRD 74
D + E D+ E R +R+ + D E + S+ R + + D++ S+ RD + RD
Sbjct: 497 DRESREGRDRREVRDNRDHREPRDSRDNRETRDSREYRDAKESRDQKDSRSTRDTHEYRD 556
Query: 75 KERHRSGR-----DRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERRERER-- 127
++ S R D R+ + +SR R+ ++ R ++R + +R R R R
Sbjct: 557 RDNRESHRKDEQYDERSYRNHGRDDTSRAESRNETRNDSRNENRSDTRNDRSGRARGRAP 616
Query: 128 ---EKERERERSRRSKSRSERDREIEREER----ERSRRSISRSERDREREREERDRSRR 180
EK RS ++ + S + E R ER R RD +R DR RR
Sbjct: 617 DPSEKTGRAARSSQADNHSSSNYHDNWESRSSYTERDRYDNRDQGRDSSFDRRHGDRDRR 676
Query: 181 SRSRSER 187
R R +R
Sbjct: 677 DRDRDQR 683
Score = 42.0 bits (97), Expect = 0.010
Identities = 35/120 (29%), Positives = 47/120 (39%), Gaps = 5/120 (4%)
Query: 77 RHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERS 136
RHR R R S+R + R +R++ + R + +RER+
Sbjct: 407 RHR--RSPSPPYQRTASPSARRQSTSPYTTRTSSSPQRKRSPSKHRSPTREKGRHDRERA 464
Query: 137 RRSKSRS-ERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSERDFEMRDSR 195
S RS ER E +R+R RD RE RDR +R R E RDSR
Sbjct: 465 SASHDRSHERRDESRGRKRDRDHNREPSGSRDDRESREGRDRREVRDNRDHR--EPRDSR 522
Score = 41.2 bits (95), Expect = 0.016
Identities = 48/227 (21%), Positives = 81/227 (35%), Gaps = 57/227 (25%)
Query: 10 EKTVEELEDKD-SKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRD 68
E+ E D++ ++ E + ER K E E G E R + R + + R ++D+
Sbjct: 785 ERERERERDRERERERERERERERDREKEKERERGRERDRDRPRDWEEKEKAREDRRDK- 843
Query: 69 RDDDRDKER-----------------------HRSGRDRDRDRDRDGERSSRDRDRDREK 105
RDD R+ +R H+ R R R+ R S R R+
Sbjct: 844 RDDVREDKRELHEDRKPKSEKGKIEGQINQNLHKDQRKRHRNESSPSPRQSPKRRREHSP 903
Query: 106 DRDREK---DRREKEK---------------------------ERERREREREKERERER 135
D D D+ EK + + E R+ ER++ R
Sbjct: 904 DSDAYNSGDDKNEKHRLLSQVVKPLDSRSLSPAHVTEERPSRWKEEERKSERKESSRRYE 963
Query: 136 SRRSKSRSERDREIEREERERSRRSISRSERDR--EREREERDRSRR 180
+K ++ E +RE ++ E D + + EE+D S +
Sbjct: 964 ESETKEKAIPAAEKQREHLGEPSENLKVKEPDTAIQHKAEEKDISEK 1010
Score = 38.9 bits (89), Expect = 0.081
Identities = 32/129 (24%), Positives = 57/129 (43%), Gaps = 14/129 (10%)
Query: 47 KRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKD 106
+RS R GD ER+ K ++ D + K R + S ++ R +
Sbjct: 75 RRSPERPPGDLR-ERMKNKRQEVDSESQK------------RTTEESTSPSRKESSRGRH 121
Query: 107 RDREKDRREKEKERERREREREKERERERSRRSKSRSERDREIERE-ERERSRRSISRSE 165
R++E + KE+ E E E E R+ S + D E+ E +R++ +R + + E
Sbjct: 122 REKEDIKITKERTPESDEETAEWETTRDDSDNGDVNYDYDHELSLEKKRQKIQRELMKLE 181
Query: 166 RDREREREE 174
++ +REE
Sbjct: 182 QENMEKREE 190
Score = 37.7 bits (86), Expect = 0.18
Identities = 34/166 (20%), Positives = 70/166 (41%), Gaps = 8/166 (4%)
Query: 21 SKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRS 80
S + D ER KR E++ S++R++ + S+K+ R R+KE +
Sbjct: 77 SPERPPGDLRERMKNKRQEVDS-----ESQKRTTEESTSP--SRKESSRGRHREKEDIKI 129
Query: 81 GRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRSK 140
++R + D + RD D + + D E E++R++ +RE + + + +
Sbjct: 130 TKERTPESDEETAEWETTRDDSDNGDVNYDYD-HELSLEKKRQKIQRELMKLEQENMEKR 188
Query: 141 SRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSE 186
+EI E + S +S R +R+ + + S+ +
Sbjct: 189 EEIVIKKEISPEVIPKMSPSPRKSSRSPKRKSSPKPTNVSSKKEKK 234
Score = 37.7 bits (86), Expect = 0.18
Identities = 40/189 (21%), Positives = 83/189 (43%), Gaps = 5/189 (2%)
Query: 2 DFDEYEYLEKTVEELEDKDSK-KNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDE 60
D+D LEK ++++ + K + E+ +K E K++ + + R S
Sbjct: 159 DYDHELSLEKKRQKIQRELMKLEQENMEKREEIVIKKEISPEVIPKMSPSPRKSSRSPKR 218
Query: 61 RVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKER 120
+ S K + ++K+ + + R +S++ + + + E +
Sbjct: 219 KSSPKPTNVSSKKEKKSVTASPPASDQQTRHS-KSAQSKKKGPRTPSPPPPTQEEALFSK 277
Query: 121 ERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRR 180
+ +E+ + K+R ER + K R RD E ++++E+ R + S R ++R DRS
Sbjct: 278 KHKEKHKSKDRIDERIKDVKERG-RDVEKPKDKKEKQRDASGGSHR-QKRSPSPADRSCS 335
Query: 181 SRSRSERDF 189
+ S S RD+
Sbjct: 336 NSSHS-RDY 343
Score = 36.2 bits (82), Expect = 0.52
Identities = 37/165 (22%), Positives = 68/165 (40%), Gaps = 13/165 (7%)
Query: 5 EYEYLEKTVEELEDKD------SKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGD 58
E E +EK E + K+ K + S K+ RS KR T K + S
Sbjct: 181 EQENMEKREEIVIKKEISPEVIPKMSPSPRKSSRS-PKRKSSPKPTNVSSKKEKKSVTAS 239
Query: 59 DERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDR--DREKDRREK 116
++ R + K++ + S + +++ + KDR +R KD +E+
Sbjct: 240 PPASDQQTRHSKSAQSKKKGPRTPSPPPPTQEEALFSKKHKEKHKSKDRIDERIKDVKER 299
Query: 117 ----EKERERREREREKERERERSRRSKSRSERDREIEREERERS 157
EK ++++E++R+ R +RS S ++R R+ S
Sbjct: 300 GRDVEKPKDKKEKQRDASGGSHRQKRSPSPADRSCSNSSHSRDYS 344
Score = 34.3 bits (77), Expect = 2.0
Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 4/107 (3%)
Query: 92 GERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSERDREIER 151
G+ R +++ +E D + +K E+ R+E R + RE+E + +K R+ E E
Sbjct: 83 GDLRERMKNKRQEVDSESQKRTTEESTSPSRKESSRGRHREKEDIKITKERTPESDE-ET 141
Query: 152 EERERSRRSISRSERDRERERE---ERDRSRRSRSRSERDFEMRDSR 195
E E +R + + + + E E+ R + R + + E + R
Sbjct: 142 AEWETTRDDSDNGDVNYDYDHELSLEKKRQKIQRELMKLEQENMEKR 188
Score = 33.1 bits (74), Expect = 4.4
Identities = 32/168 (19%), Positives = 73/168 (43%), Gaps = 11/168 (6%)
Query: 9 LEKTVEELEDKDSKK---NESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER---V 62
+E + + KD +K NESS +S ++R E S +SGD +E+ +
Sbjct: 867 IEGQINQNLHKDQRKRHRNESSPSPRQSPKRRRE-----HSPDSDAYNSGDDKNEKHRLL 921
Query: 63 SKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERER 122
S+ + D H + R ++ + + ++ R E+ +EK EK+RE
Sbjct: 922 SQVVKPLDSRSLSPAHVTEERPSRWKEEERKSERKESSRRYEESETKEKAIPAAEKQREH 981
Query: 123 REREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRER 170
E + +E + ++E E+ ++++++ + ++ +++
Sbjct: 982 LGEPSENLKVKEPDTAIQHKAEEKDISEKVPDDKAKKTKLQKKKKKKK 1029
>gb|AAP37483.1| hypothetical protein [Homo sapiens] gi|31982941|ref|NP_055885.2|
KIAA0853 [Homo sapiens]
Length = 1564
Score = 133 bits (335), Expect = 2e-30
Identities = 85/189 (44%), Positives = 127/189 (66%), Gaps = 16/189 (8%)
Query: 18 DKDSKKNESSDKTE----RSYRKRDEIEDGTEEKRSKRRSS--GDGDDERVSKKDRDRDD 71
++D + N D+ R + DE+E +E+R +RR D DER ++DR+R+
Sbjct: 628 ERDRRDNRERDQRPSSPIRHQGRNDELE--RDERREERRVDRVDDRRDERARERDRERER 685
Query: 72 DRDKERHRSG-RDRDRDRDRDGERS-SRDRDRDREKDRDREKDR-REKEKERER-RERER 127
DR++ER R RDR+R+++R+ ER +R+R+R+REK+RDRE+DR R+ ++ERER RER+R
Sbjct: 686 DRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDR 745
Query: 128 EKERERERSRRSKSRS-ERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSE 186
EKERERER R + R ER+RE ER ERER R ER+R+R+ E++D+ R R R +
Sbjct: 746 EKEREREREERERERERERERERER-ERERERARERDKERERQRDWEDKDKGRDDR-REK 803
Query: 187 RDFEMRDSR 195
R+ E+R+ R
Sbjct: 804 RE-EIREDR 811
Score = 126 bits (316), Expect = 4e-28
Identities = 79/189 (41%), Positives = 115/189 (60%), Gaps = 17/189 (8%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKR--SKRRSSGDGD----DERVSKKDRDRDD 71
++D++ ER + +RD ++ ++R S R G D DER ++ DR D
Sbjct: 610 ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 669
Query: 72 DRDKERHRSGRDRDRDRDRDGERS---SRDRDRDREKDRDREKDR-REKEKERER---RE 124
DR ER R+RDR+R+RD ER R+RDR+REK+R+ E++R RE+E+ERE+ RE
Sbjct: 670 DRRDER---ARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726
Query: 125 REREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSR 184
R+R+++ +RER R + E++RE EREERER R ER+RERER ER R R
Sbjct: 727 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERER-ERARERDKERE 785
Query: 185 SERDFEMRD 193
+RD+E +D
Sbjct: 786 RQRDWEDKD 794
Score = 124 bits (311), Expect = 1e-27
Identities = 75/191 (39%), Positives = 111/191 (57%), Gaps = 21/191 (10%)
Query: 23 KNESSDKTERSYRKR-DEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERH--- 78
+N+ ++ ER +R D ++D +E+ +R + D ER +++R+RD +R+KER
Sbjct: 650 RNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 709
Query: 79 ----------RSGRDRDRDRDRDGERS-SRDRDRDREKDRDREKDRREKEKERER-RERE 126
RDR+RDRDRD +R R+R+RDREK+R+RE++ RE+E+ERER RERE
Sbjct: 710 ERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 769
Query: 127 REKERERERSR---RSKSRSERDREIEREERERSRRSI--SRSERDREREREERDRSRRS 181
RE+ERER R R R + R D++ R++R R I R+ RD ER+ + R R
Sbjct: 770 RERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 829
Query: 182 RSRSERDFEMR 192
S S R R
Sbjct: 830 GSPSPRQSPKR 840
Score = 106 bits (264), Expect = 4e-22
Identities = 77/193 (39%), Positives = 105/193 (53%), Gaps = 18/193 (9%)
Query: 15 ELEDKDSKKN-ESSDKTERSYRKRDEI--EDGTEEKRSKRRSSGDGDDERVSKKDRD--- 68
+++ S N S +T SY +RD D ++ R G+ +R ++RD
Sbjct: 582 QIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRP 641
Query: 69 ----RDDDRDKERHRSGRDRDRDRDR-DGERSSRDRDRDREKDRDREKDRREKEKERERR 123
R R+ E R R +R DR D R R R+RDRE++RDRE RE+E+ERER
Sbjct: 642 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRE---RERERERER- 697
Query: 124 EREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE-ERDRSRRSR 182
+REREKERE ER R + ER++E +RE R+R R ER+RER+RE ER+R R R
Sbjct: 698 DREREKERELERERAREREREREKERDRE-RDRDRDHDRERERERERDREKEREREREER 756
Query: 183 SRSERDFEMRDSR 195
R ER+ E R
Sbjct: 757 ER-ERERERERER 768
Score = 103 bits (256), Expect = 3e-21
Identities = 62/182 (34%), Positives = 106/182 (58%), Gaps = 17/182 (9%)
Query: 10 EKTVEELEDK-DSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRS-----SGDGDDERVS 63
E+ V+ ++D+ D + E + ER + E E + +R K R + + + ER
Sbjct: 662 ERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREK 721
Query: 64 KKDRDRDDDRDKERHRSG-RDRDRDRDRDGERSSRDRDRDREKDRDREKDR-----REKE 117
++DR+RD DRD +R R R+RDR+++R+ ER R+R+R+RE++R+RE++R RE++
Sbjct: 722 ERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERD 781
Query: 118 KERERRE--REREKERERERSRRS---KSRSERDREIEREERERSRRSISRSERDRERER 172
KERER+ +++K R+ R +R + R+ RD ER+ ++R R S S R + R
Sbjct: 782 KERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR 841
Query: 173 EE 174
E
Sbjct: 842 RE 843
Score = 88.6 bits (218), Expect = 9e-17
Identities = 71/228 (31%), Positives = 101/228 (44%), Gaps = 42/228 (18%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEE-KRSKRRSSGDGDDERVSKKDRD 68
E + E+ ++ ++ S + +R R R + + E+ R R S D + D
Sbjct: 537 ESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSW 596
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDRE------------------ 110
ER R +RD+ RD R +RDR +R+R+
Sbjct: 597 ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELER 656
Query: 111 ---------------KDRREKEKERER---REREREKERERERSRRSKSRSERDREIERE 152
+D R +E++RER RERERE+ERER+R R + ER+R ERE
Sbjct: 657 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 716
Query: 153 ---ERERSRRSISRSERDRERERE-ERDRSR-RSRSRSERDFEMRDSR 195
E+ER R + DRERERE ERDR + R R R ER+ E R
Sbjct: 717 REREKERDRERDRDRDHDRERERERERDREKEREREREERERERERER 764
Score = 79.0 bits (193), Expect = 7e-14
Identities = 71/199 (35%), Positives = 94/199 (46%), Gaps = 21/199 (10%)
Query: 11 KTVEELEDKDSKKNESSDKT-ERSYR----KRDEIEDGTEEKR------SKRRSSGDGDD 59
K V +D +K +S + T ER R KR E T R S RRSS + D
Sbjct: 1225 KRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDR 1284
Query: 60 ERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERS---SRDRDRD--REKDRDREKDRR 114
+ S+ DR +ER R DR+R+R+R R RD D+D R +DRDR R
Sbjct: 1285 QVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDR---LR 1341
Query: 115 EKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREE 174
E+E+ERE R++ R+ +RERER +RDR+ +R S+ R E E E E
Sbjct: 1342 ERERERE-RDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGE-HE 1399
Query: 175 RDRSRRSRSRSERDFEMRD 193
RD SR D E D
Sbjct: 1400 RDLESTSRDSLALDKERMD 1418
Score = 78.2 bits (191), Expect = 1e-13
Identities = 50/197 (25%), Positives = 94/197 (47%), Gaps = 13/197 (6%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRD-EIEDGTEEKRSKRRSSGDGDDERVSKKDRD 68
E+ E+ D++ ++ D+ R+RD E E E + +R + + ER +++R+
Sbjct: 716 EREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERE 775
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEK--------ER 120
R +RDKER R D+D+ RD R R+ R+ RD +R+ K++ R
Sbjct: 776 RARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPR 835
Query: 121 ERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERE----REERD 176
+ +R RE + + ++E+ R + + R + RS+S S +R+ E+R
Sbjct: 836 QSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRK 895
Query: 177 RSRRSRSRSERDFEMRD 193
R+ SR + E+++
Sbjct: 896 PERKESSRRYEEQELKE 912
Score = 74.3 bits (181), Expect = 2e-12
Identities = 71/223 (31%), Positives = 99/223 (43%), Gaps = 35/223 (15%)
Query: 7 EYLEKTVEELEDKDSKKN-ESSDKTERSYRKRDEIEDG-TEEKRSKRRSSGDGDDERVSK 64
+Y T E + +DS+ ++ D +R R ED EE RS R+ + R
Sbjct: 484 DYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEI 543
Query: 65 KDRDRDDDRDKERH-RSGRDRDR--DRDRDGERSSRDR---------------------- 99
++ R++ R + R+ R GR R R + G R SR
Sbjct: 544 RNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYP 603
Query: 100 DRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSE-RDREIEREERERSR 158
+RDR +RD R+ ER ER+R RER++ S R + R+ E+ER+ER R
Sbjct: 604 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 663
Query: 159 R----SISRSERDREREREERDRSR-RSRSRS-ERDFEMRDSR 195
R R ER RER+RE R+R R R R R ERD E R
Sbjct: 664 RVDRVDDRRDERARERDRE-RERDRERERERERERDREREKER 705
Score = 72.0 bits (175), Expect = 9e-12
Identities = 60/205 (29%), Positives = 109/205 (52%), Gaps = 33/205 (16%)
Query: 13 VEELEDKDSKKNESSDKTE-RSYRKRDEIEDGTEEKRSKRRSSGDGDD-ERVSKKDRDRD 70
+++L+ + ++ SSD+ + RS+ R E R SG D +R+ ++DR +
Sbjct: 1251 IDQLKRGEPSRSTSSDRQDSRSHSSR---RSSPESDRQVHSRSGSFDSRDRLQERDR-YE 1306
Query: 71 DDRDKERHRSG---RDRDRDRDRDGERSSRDRDR----DREKDRDREKDRREKEKERERR 123
DR++ER R R+ DRD D+D R+ RDRDR +RE++RD+ RR+ ++ERER
Sbjct: 1307 HDRERERERRDTRQREWDRDADKDWPRN-RDRDRLRERERERERDK---RRDLDRERERL 1362
Query: 124 -----EREREKERER-------ERSRRSKSRSERDREIEREERERSRRSISRSERDRE-- 169
ER+R+++R+R E +R +++ E + E + E R ++ + D++
Sbjct: 1363 ISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLG 1422
Query: 170 --REREERDRSRRSRSRSERDFEMR 192
+ E+ ++S R+ S D E +
Sbjct: 1423 SVQGFEDTNKSERTESLEAGDDESK 1447
Score = 69.3 bits (168), Expect = 6e-11
Identities = 61/197 (30%), Positives = 87/197 (43%), Gaps = 15/197 (7%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKR--RSSGDGDDERVSKKDR 67
EK + E + ++ E + KRD +D EE+ ++ SS D D+R + R
Sbjct: 397 EKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 456
Query: 68 DRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKE----KERERR 123
DR D RD R RD RD R RD RD ++ RD R ++ ++RE R
Sbjct: 457 DRRDARDTRDRRELRD---SRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGR 513
Query: 124 EREREKERERERSR---RSKSRSERDR-EIEREERERSRRSI--SRSERDREREREERDR 177
+ R+++ E SR R+ R E R EI E R SR I R R R R E ++
Sbjct: 514 DTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEK 573
Query: 178 SRRSRSRSERDFEMRDS 194
R S+ D +S
Sbjct: 574 GSRGSRGSQIDSHSSNS 590
Score = 62.0 bits (149), Expect = 9e-09
Identities = 45/151 (29%), Positives = 63/151 (40%), Gaps = 5/151 (3%)
Query: 48 RSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGER---SSRDRDRDRE 104
RS R G D ER S+ R + R+ R + R++D +R+ E+ SSRD DRE
Sbjct: 392 RSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDRE 451
Query: 105 KDRDREKDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRS 164
R DRR+ R+RRE ++ R R SR ++ R+ R R
Sbjct: 452 PRDGR--DRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRD 509
Query: 165 ERDREREREERDRSRRSRSRSERDFEMRDSR 195
R+ R+E SRS SR
Sbjct: 510 REGRDTHRKEDTYPEESRSYGRNHLREESSR 540
Score = 60.5 bits (145), Expect = 3e-08
Identities = 60/199 (30%), Positives = 79/199 (39%), Gaps = 29/199 (14%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKR--SKRRSS-GDGDDERVSKKDRDRDDDRD 74
++DS + + E+ IED K KR SS G R R R D
Sbjct: 1153 NEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSND 1212
Query: 75 KERHRSGRD------------RDRDRDRD----GERSSR-DRDRDREKDRDREKDRREKE 117
HRSG D RDR++ + GER SR D+ + E R DR++
Sbjct: 1213 SA-HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSR 1271
Query: 118 KERERREREREKERERERSRRSKSRS---ERDREIEREERERSRRSISRSERDRERERE- 173
RR + RS SR ERDR ERER RR + E DR+ +++
Sbjct: 1272 SHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDW 1331
Query: 174 ----ERDRSRRSRSRSERD 188
+RDR R ERD
Sbjct: 1332 PRNRDRDRLRERERERERD 1350
Score = 59.3 bits (142), Expect = 6e-08
Identities = 42/146 (28%), Positives = 59/146 (39%), Gaps = 1/146 (0%)
Query: 51 RRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDRE 110
RRS+ +S R + R + R D +R +R D RDRE
Sbjct: 368 RRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDRE 427
Query: 111 KDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRER 170
KD RE+ + + + R+ +RE R RD RE R+ SR RD R
Sbjct: 428 KDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR 487
Query: 171 EREERDRSRRSRS-RSERDFEMRDSR 195
+ +E R SRS R D+ R+ R
Sbjct: 488 DTKESRDPRDSRSTRDAHDYRDREGR 513
Score = 59.3 bits (142), Expect = 6e-08
Identities = 54/181 (29%), Positives = 84/181 (45%), Gaps = 26/181 (14%)
Query: 22 KKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSG 81
K ++T +S+ +R E + T KR D E+ S+++R+ + D+ R
Sbjct: 398 KGRHDHERTSQSHDRRHERREDTRGKR---------DREKDSREEREYEQDQSSSRDH-- 446
Query: 82 RDRDRDRDRDGERSSRDRDRDREKDRDRE--KDRREKEKERERREREREKERERERSRRS 139
RD RDG RDR RD RDR +D R+ RE R+ R+ + R+ R S
Sbjct: 447 --RDDREPRDG----RDR-RDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRD-PRDS 498
Query: 140 KSRSERDREIEREERERSRRSISRSERD----REREREERDRSR-RSRSRSERDFEMRDS 194
+S + +RE R+ R+ + E R REE R+ R+ SR+E E+R+
Sbjct: 499 RSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRND 558
Query: 195 R 195
R
Sbjct: 559 R 559
Score = 59.3 bits (142), Expect = 6e-08
Identities = 42/140 (30%), Positives = 65/140 (46%), Gaps = 12/140 (8%)
Query: 60 ERVSKKDRDRDDDRDKERH---RSGRDRDRDRDR-DGERSSRDRDRDREKDRDREKDRRE 115
+R R R R+K RH R+ + DR +R + R RDR++D ++R+ E+D+
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442
Query: 116 KEKERERREREREKERERERSRRSKSRSERDREIEREERE-RSRRSISRSERDREREREE 174
R+ RE R+ R +R RDR R+ R+ R R + RD + R+
Sbjct: 443 SRDHRDDRE-------PRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDP 495
Query: 175 RDRSRRSRSRSERDFEMRDS 194
RD + RD E RD+
Sbjct: 496 RDSRSTRDAHDYRDREGRDT 515
Score = 57.4 bits (137), Expect = 2e-07
Identities = 45/190 (23%), Positives = 88/190 (45%), Gaps = 20/190 (10%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKE 76
EDKD +++ +K E R+ DG +E++SK+R +G R R+ D +
Sbjct: 791 EDKDKGRDDRREKREEIREDRNP-RDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSD 849
Query: 77 RHRSGRDRDR-----------DRDRDGERSSRDRDRD-REKDRDREKDRREKEK---ERE 121
+ SG D++ R S DR R K+ DR+ +R+E + E+E
Sbjct: 850 AYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQE 909
Query: 122 RREREREKERERERSRRSKSRSERDREI----EREERERSRRSISRSERDREREREERDR 177
+E+ +++RE++ +S R ++I + E+RE S R+ +++ + +++ +
Sbjct: 910 LKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKK 969
Query: 178 SRRSRSRSER 187
+ ER
Sbjct: 970 KKEDDVGIER 979
Score = 55.5 bits (132), Expect = 8e-07
Identities = 48/213 (22%), Positives = 85/213 (39%), Gaps = 31/213 (14%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVS 63
D + E+ EE E + ++ E + ER R+R D E++ G D+R
Sbjct: 744 DREKEREREREERERERERERERERERERE-RERARERDKERERQRDWEDKDKGRDDRRE 802
Query: 64 KKDRDRDDDRDKERH--RSGRDRDRDRDRDGERSSRDRDRDREKDRDREK---DRREKEK 118
K++ R+D ++ H R + R R+ R S R R+ D D D+ EK +
Sbjct: 803 KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHR 862
Query: 119 ---------------------ERERREREREKERERERSRRSKSRSERDREIEREERERS 157
+R+ R +E +++ ER+ S R E ++ +++R
Sbjct: 863 LLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQRE 922
Query: 158 RRSISRSERDRERE----REERDRSRRSRSRSE 186
+ I S R R ++ + DR R+ E
Sbjct: 923 QTEILESSRMRAQDIIGHHQSEDRETSDRAHDE 955
Score = 55.1 bits (131), Expect = 1e-06
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 16/196 (8%)
Query: 12 TVEELEDKD--SKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
T+E+ + + +K SS + RS R + S RS D + R
Sbjct: 1174 TIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSR 1233
Query: 70 DDDRDKERHRSGRDRDR-DRDRDGERSSRDRDRDREKDRDREKDRREKEKERERRERERE 128
D ++ K +G + R D+ + GE SR DR+ R R E +R+ R
Sbjct: 1234 DREKTKSLEITGERKSRIDQLKRGE-PSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGS 1292
Query: 129 KERERERSRRSKSRSERDREIEREERERSRRSISRS---------ERDRERERE-ERDRS 178
+ R + +R+RE RE R+ +R R +RDR RERE ER+R
Sbjct: 1293 FDSRDRLQERDRYEHDRERE--RERRDTRQREWDRDADKDWPRNRDRDRLRERERERERD 1350
Query: 179 RRSRSRSERDFEMRDS 194
+R ER+ + DS
Sbjct: 1351 KRRDLDRERERLISDS 1366
Score = 49.3 bits (116), Expect = 6e-05
Identities = 59/247 (23%), Positives = 102/247 (40%), Gaps = 62/247 (25%)
Query: 9 LEKTVEELEDKDSKKNESSDKTERSY---------RKRDEIEDGTEEKRSKRRSSGDGDD 59
L K+ + + K S K+ S+ K +R ++R+ + +++K + S
Sbjct: 212 LRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIP 271
Query: 60 ERVSK----KDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRD------------- 102
E ++ K++ + DR +E+ R G+DR RD +R +R RD+ R
Sbjct: 272 EDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFER--QREKRDKPRSTSPAGQHHSPISS 329
Query: 103 -REKDRDREKDRREKEKERERRER-----------------------------EREKERE 132
+ ++ RR+R +R++
Sbjct: 330 RHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPP 389
Query: 133 RERS-RRSKSRSERDREIEREERERSRRSISRSERDRERE-REERDRSR-RSRSRSER-D 188
R RS R K R + +R + +R RR +R +RDRE++ REER+ + +S SR R D
Sbjct: 390 RHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDD 449
Query: 189 FEMRDSR 195
E RD R
Sbjct: 450 REPRDGR 456
Score = 42.7 bits (99), Expect = 0.006
Identities = 36/153 (23%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
Query: 4 DEYEYLEKTVEELEDKDSKKNE---SSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDE 60
D YE+ + E E +D+++ E +DK R RD + + E+ +R D + E
Sbjct: 1303 DRYEHDRE--RERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERE 1360
Query: 61 RVSKKDRDRDDDRDKER----------HRSGRDRDRDRDRDGERSSRDRDRDREKDRDRE 110
R+ +RD DRD++R R + + +RD E +SRD ++ D++
Sbjct: 1361 RLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKD 1420
Query: 111 KDRREKEKERERREREREKERERERSRRSKSRS 143
+ ++ + ER E + S+ + S
Sbjct: 1421 LGSVQGFEDTNKSERTESLEAGDDESKLDDAHS 1453
Score = 38.1 bits (87), Expect = 0.14
Identities = 35/131 (26%), Positives = 59/131 (44%), Gaps = 18/131 (13%)
Query: 47 KRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKD 106
+RS R +GD ER+ K +D D + K R+ E SS ++ +
Sbjct: 75 RRSPERPTGDLR-ERMKNKRQDVDTEPQK--------------RNTEESSSPVRKESSRG 119
Query: 107 RDREKD--RREKEKERERREREREKERERERSRRSKSRSERDREIERE-ERERSRRSISR 163
R REK+ + KE+ E E E E R+ S + E+ E +R++ +R + +
Sbjct: 120 RHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMK 179
Query: 164 SERDREREREE 174
E++ +REE
Sbjct: 180 LEQENMEKREE 190
Score = 32.0 bits (71), Expect = 9.9
Identities = 28/140 (20%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGD-GDDERVSKKDRDRDDD 72
+EL++K S ++ ++TE R +D +S+ R + D DE K +
Sbjct: 908 QELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPI 967
Query: 73 RDKERHRSGRDRD--RDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKE 130
+ K+ G +R DG+ S + +K + EK R++ + + + + E ++
Sbjct: 968 KKKKEDDVGIERGNIETTSEDGQVFS---PKKGQKKKSIEKKRKKSKGDSDISDEEAAQQ 1024
Query: 131 RERERSRRSKSRSERDREIE 150
+++R R+ + ++ +E
Sbjct: 1025 SKKKRGPRTPPITTKEELVE 1044
>emb|CAI16506.1| KIAA0853 [Homo sapiens]
Length = 1169
Score = 133 bits (335), Expect = 2e-30
Identities = 85/189 (44%), Positives = 127/189 (66%), Gaps = 16/189 (8%)
Query: 18 DKDSKKNESSDKTE----RSYRKRDEIEDGTEEKRSKRRSS--GDGDDERVSKKDRDRDD 71
++D + N D+ R + DE+E +E+R +RR D DER ++DR+R+
Sbjct: 234 ERDRRDNRERDQRPSSPIRHQGRNDELE--RDERREERRVDRVDDRRDERARERDRERER 291
Query: 72 DRDKERHRSG-RDRDRDRDRDGERS-SRDRDRDREKDRDREKDR-REKEKERER-RERER 127
DR++ER R RDR+R+++R+ ER +R+R+R+REK+RDRE+DR R+ ++ERER RER+R
Sbjct: 292 DRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDR 351
Query: 128 EKERERERSRRSKSRS-ERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSE 186
EKERERER R + R ER+RE ER ERER R ER+R+R+ E++D+ R R R +
Sbjct: 352 EKEREREREERERERERERERERER-ERERERARERDKERERQRDWEDKDKGRDDR-REK 409
Query: 187 RDFEMRDSR 195
R+ E+R+ R
Sbjct: 410 RE-EIREDR 417
Score = 126 bits (316), Expect = 4e-28
Identities = 79/189 (41%), Positives = 115/189 (60%), Gaps = 17/189 (8%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKR--SKRRSSGDGD----DERVSKKDRDRDD 71
++D++ ER + +RD ++ ++R S R G D DER ++ DR D
Sbjct: 216 ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 275
Query: 72 DRDKERHRSGRDRDRDRDRDGERS---SRDRDRDREKDRDREKDR-REKEKERER---RE 124
DR ER R+RDR+R+RD ER R+RDR+REK+R+ E++R RE+E+ERE+ RE
Sbjct: 276 DRRDER---ARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 332
Query: 125 REREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSR 184
R+R+++ +RER R + E++RE EREERER R ER+RERER ER R R
Sbjct: 333 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERER-ERARERDKERE 391
Query: 185 SERDFEMRD 193
+RD+E +D
Sbjct: 392 RQRDWEDKD 400
Score = 124 bits (311), Expect = 1e-27
Identities = 75/191 (39%), Positives = 111/191 (57%), Gaps = 21/191 (10%)
Query: 23 KNESSDKTERSYRKR-DEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERH--- 78
+N+ ++ ER +R D ++D +E+ +R + D ER +++R+RD +R+KER
Sbjct: 256 RNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 315
Query: 79 ----------RSGRDRDRDRDRDGERS-SRDRDRDREKDRDREKDRREKEKERER-RERE 126
RDR+RDRDRD +R R+R+RDREK+R+RE++ RE+E+ERER RERE
Sbjct: 316 ERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 375
Query: 127 REKERERERSR---RSKSRSERDREIEREERERSRRSI--SRSERDREREREERDRSRRS 181
RE+ERER R R R + R D++ R++R R I R+ RD ER+ + R R
Sbjct: 376 RERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 435
Query: 182 RSRSERDFEMR 192
S S R R
Sbjct: 436 GSPSPRQSPKR 446
Score = 106 bits (264), Expect = 4e-22
Identities = 77/193 (39%), Positives = 105/193 (53%), Gaps = 18/193 (9%)
Query: 15 ELEDKDSKKN-ESSDKTERSYRKRDEI--EDGTEEKRSKRRSSGDGDDERVSKKDRD--- 68
+++ S N S +T SY +RD D ++ R G+ +R ++RD
Sbjct: 188 QIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRP 247
Query: 69 ----RDDDRDKERHRSGRDRDRDRDR-DGERSSRDRDRDREKDRDREKDRREKEKERERR 123
R R+ E R R +R DR D R R R+RDRE++RDRE RE+E+ERER
Sbjct: 248 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRE---RERERERER- 303
Query: 124 EREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE-ERDRSRRSR 182
+REREKERE ER R + ER++E +RE R+R R ER+RER+RE ER+R R R
Sbjct: 304 DREREKERELERERAREREREREKERDRE-RDRDRDHDRERERERERDREKEREREREER 362
Query: 183 SRSERDFEMRDSR 195
R ER+ E R
Sbjct: 363 ER-ERERERERER 374
Score = 103 bits (256), Expect = 3e-21
Identities = 62/182 (34%), Positives = 106/182 (58%), Gaps = 17/182 (9%)
Query: 10 EKTVEELEDK-DSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRS-----SGDGDDERVS 63
E+ V+ ++D+ D + E + ER + E E + +R K R + + + ER
Sbjct: 268 ERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREK 327
Query: 64 KKDRDRDDDRDKERHRSG-RDRDRDRDRDGERSSRDRDRDREKDRDREKDR-----REKE 117
++DR+RD DRD +R R R+RDR+++R+ ER R+R+R+RE++R+RE++R RE++
Sbjct: 328 ERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERD 387
Query: 118 KERERRE--REREKERERERSRRS---KSRSERDREIEREERERSRRSISRSERDRERER 172
KERER+ +++K R+ R +R + R+ RD ER+ ++R R S S R + R
Sbjct: 388 KERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR 447
Query: 173 EE 174
E
Sbjct: 448 RE 449
Score = 88.6 bits (218), Expect = 9e-17
Identities = 71/228 (31%), Positives = 101/228 (44%), Gaps = 42/228 (18%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEE-KRSKRRSSGDGDDERVSKKDRD 68
E + E+ ++ ++ S + +R R R + + E+ R R S D + D
Sbjct: 143 ESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSW 202
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDRE------------------ 110
ER R +RD+ RD R +RDR +R+R+
Sbjct: 203 ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELER 262
Query: 111 ---------------KDRREKEKERER---REREREKERERERSRRSKSRSERDREIERE 152
+D R +E++RER RERERE+ERER+R R + ER+R ERE
Sbjct: 263 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 322
Query: 153 ---ERERSRRSISRSERDRERERE-ERDRSR-RSRSRSERDFEMRDSR 195
E+ER R + DRERERE ERDR + R R R ER+ E R
Sbjct: 323 REREKERDRERDRDRDHDRERERERERDREKEREREREERERERERER 370
Score = 79.0 bits (193), Expect = 7e-14
Identities = 71/199 (35%), Positives = 94/199 (46%), Gaps = 21/199 (10%)
Query: 11 KTVEELEDKDSKKNESSDKT-ERSYR----KRDEIEDGTEEKR------SKRRSSGDGDD 59
K V +D +K +S + T ER R KR E T R S RRSS + D
Sbjct: 831 KRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDR 890
Query: 60 ERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERS---SRDRDRD--REKDRDREKDRR 114
+ S+ DR +ER R DR+R+R+R R RD D+D R +DRDR R
Sbjct: 891 QVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDR---LR 947
Query: 115 EKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREE 174
E+E+ERE R++ R+ +RERER +RDR+ +R S+ R E E E E
Sbjct: 948 ERERERE-RDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGE-HE 1005
Query: 175 RDRSRRSRSRSERDFEMRD 193
RD SR D E D
Sbjct: 1006 RDLESTSRDSLALDKERMD 1024
Score = 78.2 bits (191), Expect = 1e-13
Identities = 50/197 (25%), Positives = 94/197 (47%), Gaps = 13/197 (6%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRD-EIEDGTEEKRSKRRSSGDGDDERVSKKDRD 68
E+ E+ D++ ++ D+ R+RD E E E + +R + + ER +++R+
Sbjct: 322 EREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERE 381
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEK--------ER 120
R +RDKER R D+D+ RD R R+ R+ RD +R+ K++ R
Sbjct: 382 RARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPR 441
Query: 121 ERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERE----REERD 176
+ +R RE + + ++E+ R + + R + RS+S S +R+ E+R
Sbjct: 442 QSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRK 501
Query: 177 RSRRSRSRSERDFEMRD 193
R+ SR + E+++
Sbjct: 502 PERKESSRRYEEQELKE 518
Score = 74.3 bits (181), Expect = 2e-12
Identities = 71/223 (31%), Positives = 99/223 (43%), Gaps = 35/223 (15%)
Query: 7 EYLEKTVEELEDKDSKKN-ESSDKTERSYRKRDEIEDG-TEEKRSKRRSSGDGDDERVSK 64
+Y T E + +DS+ ++ D +R R ED EE RS R+ + R
Sbjct: 90 DYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEI 149
Query: 65 KDRDRDDDRDKERH-RSGRDRDR--DRDRDGERSSRDR---------------------- 99
++ R++ R + R+ R GR R R + G R SR
Sbjct: 150 RNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYP 209
Query: 100 DRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSE-RDREIEREERERSR 158
+RDR +RD R+ ER ER+R RER++ S R + R+ E+ER+ER R
Sbjct: 210 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 269
Query: 159 R----SISRSERDREREREERDRSR-RSRSRS-ERDFEMRDSR 195
R R ER RER+RE R+R R R R R ERD E R
Sbjct: 270 RVDRVDDRRDERARERDRE-RERDRERERERERERDREREKER 311
Score = 71.6 bits (174), Expect = 1e-11
Identities = 60/179 (33%), Positives = 100/179 (55%), Gaps = 24/179 (13%)
Query: 13 VEELEDKDSKKNESSDKTE-RSYRKRDEIEDGTEEKRSKRRSSGDGDD-ERVSKKDRDRD 70
+++L+ + ++ SSD+ + RS+ R E R SG D +R+ ++DR +
Sbjct: 857 IDQLKRGEPSRSTSSDRQDSRSHSSR---RSSPESDRQVHSRSGSFDSRDRLQERDR-YE 912
Query: 71 DDRDKERHRSG---RDRDRDRDRDGERSSRDRDR----DREKDRDREKDRREKEKERER- 122
DR++ER R R+ DRD D+D R+ RDRDR +RE++RD+ RR+ ++ERER
Sbjct: 913 HDRERERERRDTRQREWDRDADKDWPRN-RDRDRLRERERERERDK---RRDLDRERERL 968
Query: 123 --REREREKERERERSRRSKSRSERDREIERE---ERERSRRSISRSERDREREREERD 176
ER+++R+R+R+ S S+ E + E + E ER S SR ++ER ++D
Sbjct: 969 ISDSVERDRDRDRDRTFES-SQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKD 1026
Score = 69.3 bits (168), Expect = 6e-11
Identities = 61/197 (30%), Positives = 87/197 (43%), Gaps = 15/197 (7%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKR--RSSGDGDDERVSKKDR 67
EK + E + ++ E + KRD +D EE+ ++ SS D D+R + R
Sbjct: 3 EKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 62
Query: 68 DRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKE----KERERR 123
DR D RD R RD RD R RD RD ++ RD R ++ ++RE R
Sbjct: 63 DRRDARDTRDRRELRD---SRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGR 119
Query: 124 EREREKERERERSR---RSKSRSERDR-EIEREERERSRRSI--SRSERDREREREERDR 177
+ R+++ E SR R+ R E R EI E R SR I R R R R E ++
Sbjct: 120 DTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEK 179
Query: 178 SRRSRSRSERDFEMRDS 194
R S+ D +S
Sbjct: 180 GSRGSRGSQIDSHSSNS 196
Score = 60.5 bits (145), Expect = 3e-08
Identities = 60/199 (30%), Positives = 79/199 (39%), Gaps = 29/199 (14%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKR--SKRRSS-GDGDDERVSKKDRDRDDDRD 74
++DS + + E+ IED K KR SS G R R R D
Sbjct: 759 NEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSND 818
Query: 75 KERHRSGRD------------RDRDRDRD----GERSSR-DRDRDREKDRDREKDRREKE 117
HRSG D RDR++ + GER SR D+ + E R DR++
Sbjct: 819 SA-HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSR 877
Query: 118 KERERREREREKERERERSRRSKSRS---ERDREIEREERERSRRSISRSERDRERERE- 173
RR + RS SR ERDR ERER RR + E DR+ +++
Sbjct: 878 SHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDW 937
Query: 174 ----ERDRSRRSRSRSERD 188
+RDR R ERD
Sbjct: 938 PRNRDRDRLRERERERERD 956
Score = 59.3 bits (142), Expect = 6e-08
Identities = 43/147 (29%), Positives = 61/147 (41%), Gaps = 5/147 (3%)
Query: 52 RSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGER---SSRDRDRDREKDRD 108
R G D ER S+ R + R+ R + R++D +R+ E+ SSRD DRE
Sbjct: 2 REKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDG 61
Query: 109 REKDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDR 168
R DRR+ R+RRE ++ R R SR ++ R+ R R R
Sbjct: 62 R--DRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGR 119
Query: 169 EREREERDRSRRSRSRSERDFEMRDSR 195
+ R+E SRS SR
Sbjct: 120 DTHRKEDTYPEESRSYGRNHLREESSR 146
Score = 59.3 bits (142), Expect = 6e-08
Identities = 53/171 (30%), Positives = 79/171 (45%), Gaps = 21/171 (12%)
Query: 31 ERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRD-DDRDKERHRSGRDRDRDRD 89
ER+ + D + E+ R KR D +ER ++D+ D RD R GRDR
Sbjct: 10 ERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDR----- 64
Query: 90 RDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSERDREI 149
R +RD RDR + R D R+ RE R+ R+ + R+ R S+S +
Sbjct: 65 ----RDARDT-RDRRELR----DSRDMRDSREMRDYSRDTKESRD-PRDSRSTRDAHDYR 114
Query: 150 EREERERSRRSISRSERD----REREREERDRSR-RSRSRSERDFEMRDSR 195
+RE R+ R+ + E R REE R+ R+ SR+E E+R+ R
Sbjct: 115 DREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDR 165
Score = 57.4 bits (137), Expect = 2e-07
Identities = 45/190 (23%), Positives = 88/190 (45%), Gaps = 20/190 (10%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKE 76
EDKD +++ +K E R+ DG +E++SK+R +G R R+ D +
Sbjct: 397 EDKDKGRDDRREKREEIREDRNP-RDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSD 455
Query: 77 RHRSGRDRDR-----------DRDRDGERSSRDRDRD-REKDRDREKDRREKEK---ERE 121
+ SG D++ R S DR R K+ DR+ +R+E + E+E
Sbjct: 456 AYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQE 515
Query: 122 RREREREKERERERSRRSKSRSERDREI----EREERERSRRSISRSERDREREREERDR 177
+E+ +++RE++ +S R ++I + E+RE S R+ +++ + +++ +
Sbjct: 516 LKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKK 575
Query: 178 SRRSRSRSER 187
+ ER
Sbjct: 576 KKEDDVGIER 585
Score = 55.5 bits (132), Expect = 8e-07
Identities = 48/213 (22%), Positives = 85/213 (39%), Gaps = 31/213 (14%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVS 63
D + E+ EE E + ++ E + ER R+R D E++ G D+R
Sbjct: 350 DREKEREREREERERERERERERERERERE-RERARERDKERERQRDWEDKDKGRDDRRE 408
Query: 64 KKDRDRDDDRDKERH--RSGRDRDRDRDRDGERSSRDRDRDREKDRDREK---DRREKEK 118
K++ R+D ++ H R + R R+ R S R R+ D D D+ EK +
Sbjct: 409 KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHR 468
Query: 119 ---------------------ERERREREREKERERERSRRSKSRSERDREIEREERERS 157
+R+ R +E +++ ER+ S R E ++ +++R
Sbjct: 469 LLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQRE 528
Query: 158 RRSISRSERDRERE----REERDRSRRSRSRSE 186
+ I S R R ++ + DR R+ E
Sbjct: 529 QTEILESSRMRAQDIIGHHQSEDRETSDRAHDE 561
Score = 55.1 bits (131), Expect = 1e-06
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 16/196 (8%)
Query: 12 TVEELEDKD--SKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
T+E+ + + +K SS + RS R + S RS D + R
Sbjct: 780 TIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSR 839
Query: 70 DDDRDKERHRSGRDRDR-DRDRDGERSSRDRDRDREKDRDREKDRREKEKERERRERERE 128
D ++ K +G + R D+ + GE SR DR+ R R E +R+ R
Sbjct: 840 DREKTKSLEITGERKSRIDQLKRGE-PSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGS 898
Query: 129 KERERERSRRSKSRSERDREIEREERERSRRSISRS---------ERDRERERE-ERDRS 178
+ R + +R+RE RE R+ +R R +RDR RERE ER+R
Sbjct: 899 FDSRDRLQERDRYEHDRERE--RERRDTRQREWDRDADKDWPRNRDRDRLRERERERERD 956
Query: 179 RRSRSRSERDFEMRDS 194
+R ER+ + DS
Sbjct: 957 KRRDLDRERERLISDS 972
Score = 43.5 bits (101), Expect = 0.003
Identities = 45/191 (23%), Positives = 80/191 (41%), Gaps = 20/191 (10%)
Query: 4 DEYEYLEKTVEELEDKDSKKNE---SSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDE 60
D YE+ + E E +D+++ E +DK R RD + + E+ +R D + E
Sbjct: 909 DRYEHDRE--RERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERE 966
Query: 61 RVSKKDRDRDDDRDKER----------HRSGRDRDRDRDRDGERSSRDR---DRDR-EKD 106
R+ +RD DRD++R R + + +RD E +SRD D++R +KD
Sbjct: 967 RLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKD 1026
Query: 107 RDREKDRREKEKERERREREREKERERERSRRSKSRSERDRE-IEREERERSRRSISRSE 165
+ E K E + E + + + S + E I +E + +
Sbjct: 1027 LGSVQGFEETNKSERTESLEGDDESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKR 1086
Query: 166 RDREREREERD 176
D++ E + D
Sbjct: 1087 EDQQDEEKMPD 1097
Score = 32.0 bits (71), Expect = 9.9
Identities = 28/140 (20%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGD-GDDERVSKKDRDRDDD 72
+EL++K S ++ ++TE R +D +S+ R + D DE K +
Sbjct: 514 QELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPI 573
Query: 73 RDKERHRSGRDRD--RDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKE 130
+ K+ G +R DG+ S + +K + EK R++ + + + + E ++
Sbjct: 574 KKKKEDDVGIERGNIETTSEDGQVFS---PKKGQKKKSIEKKRKKSKGDSDISDEEAAQQ 630
Query: 131 RERERSRRSKSRSERDREIE 150
+++R R+ + ++ +E
Sbjct: 631 SKKKRGPRTPPITTKEELVE 650
>emb|CAI16505.1| KIAA0853 [Homo sapiens] gi|55859588|emb|CAI10903.1| KIAA0853 [Homo
sapiens]
Length = 1668
Score = 133 bits (335), Expect = 2e-30
Identities = 85/189 (44%), Positives = 127/189 (66%), Gaps = 16/189 (8%)
Query: 18 DKDSKKNESSDKTE----RSYRKRDEIEDGTEEKRSKRRSS--GDGDDERVSKKDRDRDD 71
++D + N D+ R + DE+E +E+R +RR D DER ++DR+R+
Sbjct: 628 ERDRRDNRERDQRPSSPIRHQGRNDELE--RDERREERRVDRVDDRRDERARERDRERER 685
Query: 72 DRDKERHRSG-RDRDRDRDRDGERS-SRDRDRDREKDRDREKDR-REKEKERER-RERER 127
DR++ER R RDR+R+++R+ ER +R+R+R+REK+RDRE+DR R+ ++ERER RER+R
Sbjct: 686 DRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDR 745
Query: 128 EKERERERSRRSKSRS-ERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSE 186
EKERERER R + R ER+RE ER ERER R ER+R+R+ E++D+ R R R +
Sbjct: 746 EKEREREREERERERERERERERER-ERERERARERDKERERQRDWEDKDKGRDDR-REK 803
Query: 187 RDFEMRDSR 195
R+ E+R+ R
Sbjct: 804 RE-EIREDR 811
Score = 126 bits (316), Expect = 4e-28
Identities = 79/189 (41%), Positives = 115/189 (60%), Gaps = 17/189 (8%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKR--SKRRSSGDGD----DERVSKKDRDRDD 71
++D++ ER + +RD ++ ++R S R G D DER ++ DR D
Sbjct: 610 ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 669
Query: 72 DRDKERHRSGRDRDRDRDRDGERS---SRDRDRDREKDRDREKDR-REKEKERER---RE 124
DR ER R+RDR+R+RD ER R+RDR+REK+R+ E++R RE+E+ERE+ RE
Sbjct: 670 DRRDER---ARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726
Query: 125 REREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSR 184
R+R+++ +RER R + E++RE EREERER R ER+RERER ER R R
Sbjct: 727 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERER-ERARERDKERE 785
Query: 185 SERDFEMRD 193
+RD+E +D
Sbjct: 786 RQRDWEDKD 794
Score = 124 bits (311), Expect = 1e-27
Identities = 75/191 (39%), Positives = 111/191 (57%), Gaps = 21/191 (10%)
Query: 23 KNESSDKTERSYRKR-DEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERH--- 78
+N+ ++ ER +R D ++D +E+ +R + D ER +++R+RD +R+KER
Sbjct: 650 RNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 709
Query: 79 ----------RSGRDRDRDRDRDGERS-SRDRDRDREKDRDREKDRREKEKERER-RERE 126
RDR+RDRDRD +R R+R+RDREK+R+RE++ RE+E+ERER RERE
Sbjct: 710 ERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 769
Query: 127 REKERERERSR---RSKSRSERDREIEREERERSRRSI--SRSERDREREREERDRSRRS 181
RE+ERER R R R + R D++ R++R R I R+ RD ER+ + R R
Sbjct: 770 RERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 829
Query: 182 RSRSERDFEMR 192
S S R R
Sbjct: 830 GSPSPRQSPKR 840
Score = 106 bits (264), Expect = 4e-22
Identities = 77/193 (39%), Positives = 105/193 (53%), Gaps = 18/193 (9%)
Query: 15 ELEDKDSKKN-ESSDKTERSYRKRDEI--EDGTEEKRSKRRSSGDGDDERVSKKDRD--- 68
+++ S N S +T SY +RD D ++ R G+ +R ++RD
Sbjct: 582 QIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRP 641
Query: 69 ----RDDDRDKERHRSGRDRDRDRDR-DGERSSRDRDRDREKDRDREKDRREKEKERERR 123
R R+ E R R +R DR D R R R+RDRE++RDRE RE+E+ERER
Sbjct: 642 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRE---RERERERER- 697
Query: 124 EREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE-ERDRSRRSR 182
+REREKERE ER R + ER++E +RE R+R R ER+RER+RE ER+R R R
Sbjct: 698 DREREKERELERERAREREREREKERDRE-RDRDRDHDRERERERERDREKEREREREER 756
Query: 183 SRSERDFEMRDSR 195
R ER+ E R
Sbjct: 757 ER-ERERERERER 768
Score = 103 bits (256), Expect = 3e-21
Identities = 62/182 (34%), Positives = 106/182 (58%), Gaps = 17/182 (9%)
Query: 10 EKTVEELEDK-DSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRS-----SGDGDDERVS 63
E+ V+ ++D+ D + E + ER + E E + +R K R + + + ER
Sbjct: 662 ERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREK 721
Query: 64 KKDRDRDDDRDKERHRSG-RDRDRDRDRDGERSSRDRDRDREKDRDREKDR-----REKE 117
++DR+RD DRD +R R R+RDR+++R+ ER R+R+R+RE++R+RE++R RE++
Sbjct: 722 ERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERD 781
Query: 118 KERERRE--REREKERERERSRRS---KSRSERDREIEREERERSRRSISRSERDRERER 172
KERER+ +++K R+ R +R + R+ RD ER+ ++R R S S R + R
Sbjct: 782 KERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR 841
Query: 173 EE 174
E
Sbjct: 842 RE 843
Score = 88.6 bits (218), Expect = 9e-17
Identities = 71/228 (31%), Positives = 101/228 (44%), Gaps = 42/228 (18%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEE-KRSKRRSSGDGDDERVSKKDRD 68
E + E+ ++ ++ S + +R R R + + E+ R R S D + D
Sbjct: 537 ESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSW 596
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDRE------------------ 110
ER R +RD+ RD R +RDR +R+R+
Sbjct: 597 ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELER 656
Query: 111 ---------------KDRREKEKERER---REREREKERERERSRRSKSRSERDREIERE 152
+D R +E++RER RERERE+ERER+R R + ER+R ERE
Sbjct: 657 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 716
Query: 153 ---ERERSRRSISRSERDRERERE-ERDRSR-RSRSRSERDFEMRDSR 195
E+ER R + DRERERE ERDR + R R R ER+ E R
Sbjct: 717 REREKERDRERDRDRDHDRERERERERDREKEREREREERERERERER 764
Score = 79.0 bits (193), Expect = 7e-14
Identities = 71/199 (35%), Positives = 94/199 (46%), Gaps = 21/199 (10%)
Query: 11 KTVEELEDKDSKKNESSDKT-ERSYR----KRDEIEDGTEEKR------SKRRSSGDGDD 59
K V +D +K +S + T ER R KR E T R S RRSS + D
Sbjct: 1225 KRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDR 1284
Query: 60 ERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERS---SRDRDRD--REKDRDREKDRR 114
+ S+ DR +ER R DR+R+R+R R RD D+D R +DRDR R
Sbjct: 1285 QVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDR---LR 1341
Query: 115 EKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREE 174
E+E+ERE R++ R+ +RERER +RDR+ +R S+ R E E E E
Sbjct: 1342 ERERERE-RDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGE-HE 1399
Query: 175 RDRSRRSRSRSERDFEMRD 193
RD SR D E D
Sbjct: 1400 RDLESTSRDSLALDKERMD 1418
Score = 78.2 bits (191), Expect = 1e-13
Identities = 50/197 (25%), Positives = 94/197 (47%), Gaps = 13/197 (6%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRD-EIEDGTEEKRSKRRSSGDGDDERVSKKDRD 68
E+ E+ D++ ++ D+ R+RD E E E + +R + + ER +++R+
Sbjct: 716 EREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERE 775
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEK--------ER 120
R +RDKER R D+D+ RD R R+ R+ RD +R+ K++ R
Sbjct: 776 RARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPR 835
Query: 121 ERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERE----REERD 176
+ +R RE + + ++E+ R + + R + RS+S S +R+ E+R
Sbjct: 836 QSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRK 895
Query: 177 RSRRSRSRSERDFEMRD 193
R+ SR + E+++
Sbjct: 896 PERKESSRRYEEQELKE 912
Score = 74.3 bits (181), Expect = 2e-12
Identities = 71/223 (31%), Positives = 99/223 (43%), Gaps = 35/223 (15%)
Query: 7 EYLEKTVEELEDKDSKKN-ESSDKTERSYRKRDEIEDG-TEEKRSKRRSSGDGDDERVSK 64
+Y T E + +DS+ ++ D +R R ED EE RS R+ + R
Sbjct: 484 DYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEI 543
Query: 65 KDRDRDDDRDKERH-RSGRDRDR--DRDRDGERSSRDR---------------------- 99
++ R++ R + R+ R GR R R + G R SR
Sbjct: 544 RNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYP 603
Query: 100 DRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSE-RDREIEREERERSR 158
+RDR +RD R+ ER ER+R RER++ S R + R+ E+ER+ER R
Sbjct: 604 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 663
Query: 159 R----SISRSERDREREREERDRSR-RSRSRS-ERDFEMRDSR 195
R R ER RER+RE R+R R R R R ERD E R
Sbjct: 664 RVDRVDDRRDERARERDRE-RERDRERERERERERDREREKER 705
Score = 71.6 bits (174), Expect = 1e-11
Identities = 60/179 (33%), Positives = 100/179 (55%), Gaps = 24/179 (13%)
Query: 13 VEELEDKDSKKNESSDKTE-RSYRKRDEIEDGTEEKRSKRRSSGDGDD-ERVSKKDRDRD 70
+++L+ + ++ SSD+ + RS+ R E R SG D +R+ ++DR +
Sbjct: 1251 IDQLKRGEPSRSTSSDRQDSRSHSSR---RSSPESDRQVHSRSGSFDSRDRLQERDR-YE 1306
Query: 71 DDRDKERHRSG---RDRDRDRDRDGERSSRDRDR----DREKDRDREKDRREKEKERER- 122
DR++ER R R+ DRD D+D R+ RDRDR +RE++RD+ RR+ ++ERER
Sbjct: 1307 HDRERERERRDTRQREWDRDADKDWPRN-RDRDRLRERERERERDK---RRDLDRERERL 1362
Query: 123 --REREREKERERERSRRSKSRSERDREIERE---ERERSRRSISRSERDREREREERD 176
ER+++R+R+R+ S S+ E + E + E ER S SR ++ER ++D
Sbjct: 1363 ISDSVERDRDRDRDRTFES-SQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKD 1420
Score = 69.3 bits (168), Expect = 6e-11
Identities = 61/197 (30%), Positives = 87/197 (43%), Gaps = 15/197 (7%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKR--RSSGDGDDERVSKKDR 67
EK + E + ++ E + KRD +D EE+ ++ SS D D+R + R
Sbjct: 397 EKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 456
Query: 68 DRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKE----KERERR 123
DR D RD R RD RD R RD RD ++ RD R ++ ++RE R
Sbjct: 457 DRRDARDTRDRRELRD---SRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGR 513
Query: 124 EREREKERERERSR---RSKSRSERDR-EIEREERERSRRSI--SRSERDREREREERDR 177
+ R+++ E SR R+ R E R EI E R SR I R R R R E ++
Sbjct: 514 DTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEK 573
Query: 178 SRRSRSRSERDFEMRDS 194
R S+ D +S
Sbjct: 574 GSRGSRGSQIDSHSSNS 590
Score = 62.0 bits (149), Expect = 9e-09
Identities = 45/151 (29%), Positives = 63/151 (40%), Gaps = 5/151 (3%)
Query: 48 RSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGER---SSRDRDRDRE 104
RS R G D ER S+ R + R+ R + R++D +R+ E+ SSRD DRE
Sbjct: 392 RSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDRE 451
Query: 105 KDRDREKDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRS 164
R DRR+ R+RRE ++ R R SR ++ R+ R R
Sbjct: 452 PRDGR--DRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRD 509
Query: 165 ERDREREREERDRSRRSRSRSERDFEMRDSR 195
R+ R+E SRS SR
Sbjct: 510 REGRDTHRKEDTYPEESRSYGRNHLREESSR 540
Score = 60.5 bits (145), Expect = 3e-08
Identities = 60/199 (30%), Positives = 79/199 (39%), Gaps = 29/199 (14%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKR--SKRRSS-GDGDDERVSKKDRDRDDDRD 74
++DS + + E+ IED K KR SS G R R R D
Sbjct: 1153 NEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSND 1212
Query: 75 KERHRSGRD------------RDRDRDRD----GERSSR-DRDRDREKDRDREKDRREKE 117
HRSG D RDR++ + GER SR D+ + E R DR++
Sbjct: 1213 SA-HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSR 1271
Query: 118 KERERREREREKERERERSRRSKSRS---ERDREIEREERERSRRSISRSERDRERERE- 173
RR + RS SR ERDR ERER RR + E DR+ +++
Sbjct: 1272 SHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDW 1331
Query: 174 ----ERDRSRRSRSRSERD 188
+RDR R ERD
Sbjct: 1332 PRNRDRDRLRERERERERD 1350
Score = 59.3 bits (142), Expect = 6e-08
Identities = 42/140 (30%), Positives = 65/140 (46%), Gaps = 12/140 (8%)
Query: 60 ERVSKKDRDRDDDRDKERH---RSGRDRDRDRDR-DGERSSRDRDRDREKDRDREKDRRE 115
+R R R R+K RH R+ + DR +R + R RDR++D ++R+ E+D+
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442
Query: 116 KEKERERREREREKERERERSRRSKSRSERDREIEREERE-RSRRSISRSERDREREREE 174
R+ RE R+ R +R RDR R+ R+ R R + RD + R+
Sbjct: 443 SRDHRDDRE-------PRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDP 495
Query: 175 RDRSRRSRSRSERDFEMRDS 194
RD + RD E RD+
Sbjct: 496 RDSRSTRDAHDYRDREGRDT 515
Score = 59.3 bits (142), Expect = 6e-08
Identities = 54/181 (29%), Positives = 84/181 (45%), Gaps = 26/181 (14%)
Query: 22 KKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSG 81
K ++T +S+ +R E + T KR D E+ S+++R+ + D+ R
Sbjct: 398 KGRHDHERTSQSHDRRHERREDTRGKR---------DREKDSREEREYEQDQSSSRDH-- 446
Query: 82 RDRDRDRDRDGERSSRDRDRDREKDRDRE--KDRREKEKERERREREREKERERERSRRS 139
RD RDG RDR RD RDR +D R+ RE R+ R+ + R+ R S
Sbjct: 447 --RDDREPRDG----RDR-RDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRD-PRDS 498
Query: 140 KSRSERDREIEREERERSRRSISRSERD----REREREERDRSR-RSRSRSERDFEMRDS 194
+S + +RE R+ R+ + E R REE R+ R+ SR+E E+R+
Sbjct: 499 RSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRND 558
Query: 195 R 195
R
Sbjct: 559 R 559
Score = 59.3 bits (142), Expect = 6e-08
Identities = 42/146 (28%), Positives = 59/146 (39%), Gaps = 1/146 (0%)
Query: 51 RRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDRE 110
RRS+ +S R + R + R D +R +R D RDRE
Sbjct: 368 RRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDRE 427
Query: 111 KDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRER 170
KD RE+ + + + R+ +RE R RD RE R+ SR RD R
Sbjct: 428 KDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR 487
Query: 171 EREERDRSRRSRS-RSERDFEMRDSR 195
+ +E R SRS R D+ R+ R
Sbjct: 488 DTKESRDPRDSRSTRDAHDYRDREGR 513
Score = 57.4 bits (137), Expect = 2e-07
Identities = 45/190 (23%), Positives = 88/190 (45%), Gaps = 20/190 (10%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKE 76
EDKD +++ +K E R+ DG +E++SK+R +G R R+ D +
Sbjct: 791 EDKDKGRDDRREKREEIREDRNP-RDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSD 849
Query: 77 RHRSGRDRDR-----------DRDRDGERSSRDRDRD-REKDRDREKDRREKEK---ERE 121
+ SG D++ R S DR R K+ DR+ +R+E + E+E
Sbjct: 850 AYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQE 909
Query: 122 RREREREKERERERSRRSKSRSERDREI----EREERERSRRSISRSERDREREREERDR 177
+E+ +++RE++ +S R ++I + E+RE S R+ +++ + +++ +
Sbjct: 910 LKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKK 969
Query: 178 SRRSRSRSER 187
+ ER
Sbjct: 970 KKEDDVGIER 979
Score = 55.5 bits (132), Expect = 8e-07
Identities = 48/213 (22%), Positives = 85/213 (39%), Gaps = 31/213 (14%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVS 63
D + E+ EE E + ++ E + ER R+R D E++ G D+R
Sbjct: 744 DREKEREREREERERERERERERERERERE-RERARERDKERERQRDWEDKDKGRDDRRE 802
Query: 64 KKDRDRDDDRDKERH--RSGRDRDRDRDRDGERSSRDRDRDREKDRDREK---DRREKEK 118
K++ R+D ++ H R + R R+ R S R R+ D D D+ EK +
Sbjct: 803 KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHR 862
Query: 119 ---------------------ERERREREREKERERERSRRSKSRSERDREIEREERERS 157
+R+ R +E +++ ER+ S R E ++ +++R
Sbjct: 863 LLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQRE 922
Query: 158 RRSISRSERDRERE----REERDRSRRSRSRSE 186
+ I S R R ++ + DR R+ E
Sbjct: 923 QTEILESSRMRAQDIIGHHQSEDRETSDRAHDE 955
Score = 55.1 bits (131), Expect = 1e-06
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 16/196 (8%)
Query: 12 TVEELEDKD--SKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
T+E+ + + +K SS + RS R + S RS D + R
Sbjct: 1174 TIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSR 1233
Query: 70 DDDRDKERHRSGRDRDR-DRDRDGERSSRDRDRDREKDRDREKDRREKEKERERRERERE 128
D ++ K +G + R D+ + GE SR DR+ R R E +R+ R
Sbjct: 1234 DREKTKSLEITGERKSRIDQLKRGE-PSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGS 1292
Query: 129 KERERERSRRSKSRSERDREIEREERERSRRSISRS---------ERDRERERE-ERDRS 178
+ R + +R+RE RE R+ +R R +RDR RERE ER+R
Sbjct: 1293 FDSRDRLQERDRYEHDRERE--RERRDTRQREWDRDADKDWPRNRDRDRLRERERERERD 1350
Query: 179 RRSRSRSERDFEMRDS 194
+R ER+ + DS
Sbjct: 1351 KRRDLDRERERLISDS 1366
Score = 49.3 bits (116), Expect = 6e-05
Identities = 59/247 (23%), Positives = 102/247 (40%), Gaps = 62/247 (25%)
Query: 9 LEKTVEELEDKDSKKNESSDKTERSY---------RKRDEIEDGTEEKRSKRRSSGDGDD 59
L K+ + + K S K+ S+ K +R ++R+ + +++K + S
Sbjct: 212 LRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIP 271
Query: 60 ERVSK----KDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRD------------- 102
E ++ K++ + DR +E+ R G+DR RD +R +R RD+ R
Sbjct: 272 EDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFER--QREKRDKPRSTSPAGQHHSPISS 329
Query: 103 -REKDRDREKDRREKEKERERRER-----------------------------EREKERE 132
+ ++ RR+R +R++
Sbjct: 330 RHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPP 389
Query: 133 RERS-RRSKSRSERDREIEREERERSRRSISRSERDRERE-REERDRSR-RSRSRSER-D 188
R RS R K R + +R + +R RR +R +RDRE++ REER+ + +S SR R D
Sbjct: 390 RHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDD 449
Query: 189 FEMRDSR 195
E RD R
Sbjct: 450 REPRDGR 456
Score = 43.5 bits (101), Expect = 0.003
Identities = 45/191 (23%), Positives = 80/191 (41%), Gaps = 20/191 (10%)
Query: 4 DEYEYLEKTVEELEDKDSKKNE---SSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDE 60
D YE+ + E E +D+++ E +DK R RD + + E+ +R D + E
Sbjct: 1303 DRYEHDRE--RERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERE 1360
Query: 61 RVSKKDRDRDDDRDKER----------HRSGRDRDRDRDRDGERSSRDR---DRDR-EKD 106
R+ +RD DRD++R R + + +RD E +SRD D++R +KD
Sbjct: 1361 RLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKD 1420
Query: 107 RDREKDRREKEKERERREREREKERERERSRRSKSRSERDRE-IEREERERSRRSISRSE 165
+ E K E + E + + + S + E I +E + +
Sbjct: 1421 LGSVQGFEETNKSERTESLEGDDESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKR 1480
Query: 166 RDREREREERD 176
D++ E + D
Sbjct: 1481 EDQQDEEKMPD 1491
Score = 38.1 bits (87), Expect = 0.14
Identities = 35/131 (26%), Positives = 59/131 (44%), Gaps = 18/131 (13%)
Query: 47 KRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKD 106
+RS R +GD ER+ K +D D + K R+ E SS ++ +
Sbjct: 75 RRSPERPTGDLR-ERMKNKRQDVDTEPQK--------------RNTEESSSPVRKESSRG 119
Query: 107 RDREKD--RREKEKERERREREREKERERERSRRSKSRSERDREIERE-ERERSRRSISR 163
R REK+ + KE+ E E E E R+ S + E+ E +R++ +R + +
Sbjct: 120 RHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMK 179
Query: 164 SERDREREREE 174
E++ +REE
Sbjct: 180 LEQENMEKREE 190
Score = 32.0 bits (71), Expect = 9.9
Identities = 28/140 (20%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGD-GDDERVSKKDRDRDDD 72
+EL++K S ++ ++TE R +D +S+ R + D DE K +
Sbjct: 908 QELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPI 967
Query: 73 RDKERHRSGRDRD--RDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKE 130
+ K+ G +R DG+ S + +K + EK R++ + + + + E ++
Sbjct: 968 KKKKEDDVGIERGNIETTSEDGQVFS---PKKGQKKKSIEKKRKKSKGDSDISDEEAAQQ 1024
Query: 131 RERERSRRSKSRSERDREIE 150
+++R R+ + ++ +E
Sbjct: 1025 SKKKRGPRTPPITTKEELVE 1044
>emb|CAB66679.2| hypothetical protein [Homo sapiens]
Length = 1267
Score = 133 bits (335), Expect = 2e-30
Identities = 85/189 (44%), Positives = 127/189 (66%), Gaps = 16/189 (8%)
Query: 18 DKDSKKNESSDKTE----RSYRKRDEIEDGTEEKRSKRRSS--GDGDDERVSKKDRDRDD 71
++D + N D+ R + DE+E +E+R +RR D DER ++DR+R+
Sbjct: 331 ERDRRDNRERDQRPSSPIRHQGRNDELE--RDERREERRVDRVDDRRDERARERDRERER 388
Query: 72 DRDKERHRSG-RDRDRDRDRDGERS-SRDRDRDREKDRDREKDR-REKEKERER-RERER 127
DR++ER R RDR+R+++R+ ER +R+R+R+REK+RDRE+DR R+ ++ERER RER+R
Sbjct: 389 DRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDR 448
Query: 128 EKERERERSRRSKSRS-ERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSE 186
EKERERER R + R ER+RE ER ERER R ER+R+R+ E++D+ R R R +
Sbjct: 449 EKEREREREERERERERERERERER-ERERERARERDKERERQRDWEDKDKGRDDR-REK 506
Query: 187 RDFEMRDSR 195
R+ E+R+ R
Sbjct: 507 RE-EIREDR 514
Score = 126 bits (316), Expect = 4e-28
Identities = 79/189 (41%), Positives = 115/189 (60%), Gaps = 17/189 (8%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKR--SKRRSSGDGD----DERVSKKDRDRDD 71
++D++ ER + +RD ++ ++R S R G D DER ++ DR D
Sbjct: 313 ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 372
Query: 72 DRDKERHRSGRDRDRDRDRDGERS---SRDRDRDREKDRDREKDR-REKEKERER---RE 124
DR ER R+RDR+R+RD ER R+RDR+REK+R+ E++R RE+E+ERE+ RE
Sbjct: 373 DRRDER---ARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 429
Query: 125 REREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSR 184
R+R+++ +RER R + E++RE EREERER R ER+RERER ER R R
Sbjct: 430 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERER-ERARERDKERE 488
Query: 185 SERDFEMRD 193
+RD+E +D
Sbjct: 489 RQRDWEDKD 497
Score = 124 bits (311), Expect = 1e-27
Identities = 75/191 (39%), Positives = 111/191 (57%), Gaps = 21/191 (10%)
Query: 23 KNESSDKTERSYRKR-DEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERH--- 78
+N+ ++ ER +R D ++D +E+ +R + D ER +++R+RD +R+KER
Sbjct: 353 RNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 412
Query: 79 ----------RSGRDRDRDRDRDGERS-SRDRDRDREKDRDREKDRREKEKERER-RERE 126
RDR+RDRDRD +R R+R+RDREK+R+RE++ RE+E+ERER RERE
Sbjct: 413 ERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 472
Query: 127 REKERERERSR---RSKSRSERDREIEREERERSRRSI--SRSERDREREREERDRSRRS 181
RE+ERER R R R + R D++ R++R R I R+ RD ER+ + R R
Sbjct: 473 RERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 532
Query: 182 RSRSERDFEMR 192
S S R R
Sbjct: 533 GSPSPRQSPKR 543
Score = 106 bits (264), Expect = 4e-22
Identities = 77/193 (39%), Positives = 105/193 (53%), Gaps = 18/193 (9%)
Query: 15 ELEDKDSKKN-ESSDKTERSYRKRDEI--EDGTEEKRSKRRSSGDGDDERVSKKDRD--- 68
+++ S N S +T SY +RD D ++ R G+ +R ++RD
Sbjct: 285 QIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRP 344
Query: 69 ----RDDDRDKERHRSGRDRDRDRDR-DGERSSRDRDRDREKDRDREKDRREKEKERERR 123
R R+ E R R +R DR D R R R+RDRE++RDRE RE+E+ERER
Sbjct: 345 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRE---RERERERER- 400
Query: 124 EREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE-ERDRSRRSR 182
+REREKERE ER R + ER++E +RE R+R R ER+RER+RE ER+R R R
Sbjct: 401 DREREKERELERERAREREREREKERDRE-RDRDRDHDRERERERERDREKEREREREER 459
Query: 183 SRSERDFEMRDSR 195
R ER+ E R
Sbjct: 460 ER-ERERERERER 471
Score = 103 bits (256), Expect = 3e-21
Identities = 62/182 (34%), Positives = 106/182 (58%), Gaps = 17/182 (9%)
Query: 10 EKTVEELEDK-DSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRS-----SGDGDDERVS 63
E+ V+ ++D+ D + E + ER + E E + +R K R + + + ER
Sbjct: 365 ERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREK 424
Query: 64 KKDRDRDDDRDKERHRSG-RDRDRDRDRDGERSSRDRDRDREKDRDREKDR-----REKE 117
++DR+RD DRD +R R R+RDR+++R+ ER R+R+R+RE++R+RE++R RE++
Sbjct: 425 ERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERD 484
Query: 118 KERERRE--REREKERERERSRRS---KSRSERDREIEREERERSRRSISRSERDRERER 172
KERER+ +++K R+ R +R + R+ RD ER+ ++R R S S R + R
Sbjct: 485 KERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR 544
Query: 173 EE 174
E
Sbjct: 545 RE 546
Score = 88.6 bits (218), Expect = 9e-17
Identities = 71/228 (31%), Positives = 101/228 (44%), Gaps = 42/228 (18%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEE-KRSKRRSSGDGDDERVSKKDRD 68
E + E+ ++ ++ S + +R R R + + E+ R R S D + D
Sbjct: 240 ESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSW 299
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDRE------------------ 110
ER R +RD+ RD R +RDR +R+R+
Sbjct: 300 ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELER 359
Query: 111 ---------------KDRREKEKERER---REREREKERERERSRRSKSRSERDREIERE 152
+D R +E++RER RERERE+ERER+R R + ER+R ERE
Sbjct: 360 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 419
Query: 153 ---ERERSRRSISRSERDRERERE-ERDRSR-RSRSRSERDFEMRDSR 195
E+ER R + DRERERE ERDR + R R R ER+ E R
Sbjct: 420 REREKERDRERDRDRDHDRERERERERDREKEREREREERERERERER 467
Score = 79.0 bits (193), Expect = 7e-14
Identities = 71/199 (35%), Positives = 94/199 (46%), Gaps = 21/199 (10%)
Query: 11 KTVEELEDKDSKKNESSDKT-ERSYR----KRDEIEDGTEEKR------SKRRSSGDGDD 59
K V +D +K +S + T ER R KR E T R S RRSS + D
Sbjct: 928 KRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDR 987
Query: 60 ERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERS---SRDRDRD--REKDRDREKDRR 114
+ S+ DR +ER R DR+R+R+R R RD D+D R +DRDR R
Sbjct: 988 QVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDR---LR 1044
Query: 115 EKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREE 174
E+E+ERE R++ R+ +RERER +RDR+ +R S+ R E E E E
Sbjct: 1045 ERERERE-RDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGE-HE 1102
Query: 175 RDRSRRSRSRSERDFEMRD 193
RD SR D E D
Sbjct: 1103 RDLESTSRDSLALDKERMD 1121
Score = 78.2 bits (191), Expect = 1e-13
Identities = 50/197 (25%), Positives = 94/197 (47%), Gaps = 13/197 (6%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRD-EIEDGTEEKRSKRRSSGDGDDERVSKKDRD 68
E+ E+ D++ ++ D+ R+RD E E E + +R + + ER +++R+
Sbjct: 419 EREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERE 478
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEK--------ER 120
R +RDKER R D+D+ RD R R+ R+ RD +R+ K++ R
Sbjct: 479 RARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPR 538
Query: 121 ERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERE----REERD 176
+ +R RE + + ++E+ R + + R + RS+S S +R+ E+R
Sbjct: 539 QSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRK 598
Query: 177 RSRRSRSRSERDFEMRD 193
R+ SR + E+++
Sbjct: 599 PERKESSRRYEEQELKE 615
Score = 74.3 bits (181), Expect = 2e-12
Identities = 71/223 (31%), Positives = 99/223 (43%), Gaps = 35/223 (15%)
Query: 7 EYLEKTVEELEDKDSKKN-ESSDKTERSYRKRDEIEDG-TEEKRSKRRSSGDGDDERVSK 64
+Y T E + +DS+ ++ D +R R ED EE RS R+ + R
Sbjct: 187 DYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEI 246
Query: 65 KDRDRDDDRDKERH-RSGRDRDR--DRDRDGERSSRDR---------------------- 99
++ R++ R + R+ R GR R R + G R SR
Sbjct: 247 RNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYP 306
Query: 100 DRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSE-RDREIEREERERSR 158
+RDR +RD R+ ER ER+R RER++ S R + R+ E+ER+ER R
Sbjct: 307 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 366
Query: 159 R----SISRSERDREREREERDRSR-RSRSRS-ERDFEMRDSR 195
R R ER RER+RE R+R R R R R ERD E R
Sbjct: 367 RVDRVDDRRDERARERDRE-RERDRERERERERERDREREKER 408
Score = 72.0 bits (175), Expect = 9e-12
Identities = 60/205 (29%), Positives = 109/205 (52%), Gaps = 33/205 (16%)
Query: 13 VEELEDKDSKKNESSDKTE-RSYRKRDEIEDGTEEKRSKRRSSGDGDD-ERVSKKDRDRD 70
+++L+ + ++ SSD+ + RS+ R E R SG D +R+ ++DR +
Sbjct: 954 IDQLKRGEPSRSTSSDRQDSRSHSSR---RSSPESDRQVHSRSGSFDSRDRLQERDR-YE 1009
Query: 71 DDRDKERHRSG---RDRDRDRDRDGERSSRDRDR----DREKDRDREKDRREKEKERERR 123
DR++ER R R+ DRD D+D R+ RDRDR +RE++RD+ RR+ ++ERER
Sbjct: 1010 HDRERERERRDTRQREWDRDADKDWPRN-RDRDRLRERERERERDK---RRDLDRERERL 1065
Query: 124 -----EREREKERER-------ERSRRSKSRSERDREIEREERERSRRSISRSERDRE-- 169
ER+R+++R+R E +R +++ E + E + E R ++ + D++
Sbjct: 1066 ISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLG 1125
Query: 170 --REREERDRSRRSRSRSERDFEMR 192
+ E+ ++S R+ S D E +
Sbjct: 1126 SVQGFEDTNKSERTESLEAGDDESK 1150
Score = 69.3 bits (168), Expect = 6e-11
Identities = 61/197 (30%), Positives = 87/197 (43%), Gaps = 15/197 (7%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKR--RSSGDGDDERVSKKDR 67
EK + E + ++ E + KRD +D EE+ ++ SS D D+R + R
Sbjct: 100 EKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 159
Query: 68 DRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKE----KERERR 123
DR D RD R RD RD R RD RD ++ RD R ++ ++RE R
Sbjct: 160 DRRDARDTRDRRELRD---SRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGR 216
Query: 124 EREREKERERERSR---RSKSRSERDR-EIEREERERSRRSI--SRSERDREREREERDR 177
+ R+++ E SR R+ R E R EI E R SR I R R R R E ++
Sbjct: 217 DTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEK 276
Query: 178 SRRSRSRSERDFEMRDS 194
R S+ D +S
Sbjct: 277 GSRGSRGSQIDSHSSNS 293
Score = 62.0 bits (149), Expect = 9e-09
Identities = 45/151 (29%), Positives = 63/151 (40%), Gaps = 5/151 (3%)
Query: 48 RSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGER---SSRDRDRDRE 104
RS R G D ER S+ R + R+ R + R++D +R+ E+ SSRD DRE
Sbjct: 95 RSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDRE 154
Query: 105 KDRDREKDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRS 164
R DRR+ R+RRE ++ R R SR ++ R+ R R
Sbjct: 155 PRDGR--DRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRD 212
Query: 165 ERDREREREERDRSRRSRSRSERDFEMRDSR 195
R+ R+E SRS SR
Sbjct: 213 REGRDTHRKEDTYPEESRSYGRNHLREESSR 243
Score = 60.5 bits (145), Expect = 3e-08
Identities = 60/199 (30%), Positives = 79/199 (39%), Gaps = 29/199 (14%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKR--SKRRSS-GDGDDERVSKKDRDRDDDRD 74
++DS + + E+ IED K KR SS G R R R D
Sbjct: 856 NEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSND 915
Query: 75 KERHRSGRD------------RDRDRDRD----GERSSR-DRDRDREKDRDREKDRREKE 117
HRSG D RDR++ + GER SR D+ + E R DR++
Sbjct: 916 SA-HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSR 974
Query: 118 KERERREREREKERERERSRRSKSRS---ERDREIEREERERSRRSISRSERDRERERE- 173
RR + RS SR ERDR ERER RR + E DR+ +++
Sbjct: 975 SHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDW 1034
Query: 174 ----ERDRSRRSRSRSERD 188
+RDR R ERD
Sbjct: 1035 PRNRDRDRLRERERERERD 1053
Score = 59.3 bits (142), Expect = 6e-08
Identities = 54/181 (29%), Positives = 84/181 (45%), Gaps = 26/181 (14%)
Query: 22 KKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSG 81
K ++T +S+ +R E + T KR D E+ S+++R+ + D+ R
Sbjct: 101 KGRHDHERTSQSHDRRHERREDTRGKR---------DREKDSREEREYEQDQSSSRDH-- 149
Query: 82 RDRDRDRDRDGERSSRDRDRDREKDRDRE--KDRREKEKERERREREREKERERERSRRS 139
RD RDG RDR RD RDR +D R+ RE R+ R+ + R+ R S
Sbjct: 150 --RDDREPRDG----RDR-RDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRD-PRDS 201
Query: 140 KSRSERDREIEREERERSRRSISRSERD----REREREERDRSR-RSRSRSERDFEMRDS 194
+S + +RE R+ R+ + E R REE R+ R+ SR+E E+R+
Sbjct: 202 RSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRND 261
Query: 195 R 195
R
Sbjct: 262 R 262
Score = 59.3 bits (142), Expect = 6e-08
Identities = 42/146 (28%), Positives = 59/146 (39%), Gaps = 1/146 (0%)
Query: 51 RRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDRE 110
RRS+ +S R + R + R D +R +R D RDRE
Sbjct: 71 RRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDRE 130
Query: 111 KDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRER 170
KD RE+ + + + R+ +RE R RD RE R+ SR RD R
Sbjct: 131 KDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR 190
Query: 171 EREERDRSRRSRS-RSERDFEMRDSR 195
+ +E R SRS R D+ R+ R
Sbjct: 191 DTKESRDPRDSRSTRDAHDYRDREGR 216
Score = 59.3 bits (142), Expect = 6e-08
Identities = 42/140 (30%), Positives = 65/140 (46%), Gaps = 12/140 (8%)
Query: 60 ERVSKKDRDRDDDRDKERH---RSGRDRDRDRDR-DGERSSRDRDRDREKDRDREKDRRE 115
+R R R R+K RH R+ + DR +R + R RDR++D ++R+ E+D+
Sbjct: 86 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 145
Query: 116 KEKERERREREREKERERERSRRSKSRSERDREIEREERE-RSRRSISRSERDREREREE 174
R+ RE R+ R +R RDR R+ R+ R R + RD + R+
Sbjct: 146 SRDHRDDRE-------PRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDP 198
Query: 175 RDRSRRSRSRSERDFEMRDS 194
RD + RD E RD+
Sbjct: 199 RDSRSTRDAHDYRDREGRDT 218
Score = 57.4 bits (137), Expect = 2e-07
Identities = 45/190 (23%), Positives = 88/190 (45%), Gaps = 20/190 (10%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKE 76
EDKD +++ +K E R+ DG +E++SK+R +G R R+ D +
Sbjct: 494 EDKDKGRDDRREKREEIREDRNP-RDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSD 552
Query: 77 RHRSGRDRDR-----------DRDRDGERSSRDRDRD-REKDRDREKDRREKEK---ERE 121
+ SG D++ R S DR R K+ DR+ +R+E + E+E
Sbjct: 553 AYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQE 612
Query: 122 RREREREKERERERSRRSKSRSERDREI----EREERERSRRSISRSERDREREREERDR 177
+E+ +++RE++ +S R ++I + E+RE S R+ +++ + +++ +
Sbjct: 613 LKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKK 672
Query: 178 SRRSRSRSER 187
+ ER
Sbjct: 673 KKEDDVGIER 682
Score = 55.5 bits (132), Expect = 8e-07
Identities = 48/213 (22%), Positives = 85/213 (39%), Gaps = 31/213 (14%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVS 63
D + E+ EE E + ++ E + ER R+R D E++ G D+R
Sbjct: 447 DREKEREREREERERERERERERERERERE-RERARERDKERERQRDWEDKDKGRDDRRE 505
Query: 64 KKDRDRDDDRDKERH--RSGRDRDRDRDRDGERSSRDRDRDREKDRDREK---DRREKEK 118
K++ R+D ++ H R + R R+ R S R R+ D D D+ EK +
Sbjct: 506 KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHR 565
Query: 119 ---------------------ERERREREREKERERERSRRSKSRSERDREIEREERERS 157
+R+ R +E +++ ER+ S R E ++ +++R
Sbjct: 566 LLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQRE 625
Query: 158 RRSISRSERDRERE----REERDRSRRSRSRSE 186
+ I S R R ++ + DR R+ E
Sbjct: 626 QTEILESSRMRAQDIIGHHQSEDRETSDRAHDE 658
Score = 55.1 bits (131), Expect = 1e-06
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 16/196 (8%)
Query: 12 TVEELEDKD--SKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
T+E+ + + +K SS + RS R + S RS D + R
Sbjct: 877 TIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSR 936
Query: 70 DDDRDKERHRSGRDRDR-DRDRDGERSSRDRDRDREKDRDREKDRREKEKERERRERERE 128
D ++ K +G + R D+ + GE SR DR+ R R E +R+ R
Sbjct: 937 DREKTKSLEITGERKSRIDQLKRGE-PSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGS 995
Query: 129 KERERERSRRSKSRSERDREIEREERERSRRSISRS---------ERDRERERE-ERDRS 178
+ R + +R+RE RE R+ +R R +RDR RERE ER+R
Sbjct: 996 FDSRDRLQERDRYEHDRERE--RERRDTRQREWDRDADKDWPRNRDRDRLRERERERERD 1053
Query: 179 RRSRSRSERDFEMRDS 194
+R ER+ + DS
Sbjct: 1054 KRRDLDRERERLISDS 1069
Score = 42.7 bits (99), Expect = 0.006
Identities = 36/153 (23%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
Query: 4 DEYEYLEKTVEELEDKDSKKNE---SSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDE 60
D YE+ + E E +D+++ E +DK R RD + + E+ +R D + E
Sbjct: 1006 DRYEHDRE--RERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERE 1063
Query: 61 RVSKKDRDRDDDRDKER----------HRSGRDRDRDRDRDGERSSRDRDRDREKDRDRE 110
R+ +RD DRD++R R + + +RD E +SRD ++ D++
Sbjct: 1064 RLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKD 1123
Query: 111 KDRREKEKERERREREREKERERERSRRSKSRS 143
+ ++ + ER E + S+ + S
Sbjct: 1124 LGSVQGFEDTNKSERTESLEAGDDESKLDDAHS 1156
Score = 38.9 bits (89), Expect = 0.081
Identities = 40/159 (25%), Positives = 62/159 (38%), Gaps = 47/159 (29%)
Query: 84 RDRDRDRDGERSSRDRDRD--------------REKDRDREKDRREKEKERERRER---- 125
+DR RD + +R RD+ R + ++ RR+R
Sbjct: 1 KDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSP 60
Query: 126 -------------------------EREKERERERS-RRSKSRSERDREIEREERERSRR 159
+R++ R RS R K R + +R + +R RR
Sbjct: 61 SYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERR 120
Query: 160 SISRSERDRERE-REERDRSR-RSRSRSER-DFEMRDSR 195
+R +RDRE++ REER+ + +S SR R D E RD R
Sbjct: 121 EDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 159
Score = 32.0 bits (71), Expect = 9.9
Identities = 28/140 (20%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGD-GDDERVSKKDRDRDDD 72
+EL++K S ++ ++TE R +D +S+ R + D DE K +
Sbjct: 611 QELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPI 670
Query: 73 RDKERHRSGRDRD--RDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKE 130
+ K+ G +R DG+ S + +K + EK R++ + + + + E ++
Sbjct: 671 KKKKEDDVGIERGNIETTSEDGQVFS---PKKGQKKKSIEKKRKKSKGDSDISDEEAAQQ 727
Query: 131 RERERSRRSKSRSERDREIE 150
+++R R+ + ++ +E
Sbjct: 728 SKKKRGPRTPPITTKEELVE 747
>emb|CAD38544.1| hypothetical protein [Homo sapiens]
Length = 796
Score = 133 bits (335), Expect = 2e-30
Identities = 85/189 (44%), Positives = 127/189 (66%), Gaps = 16/189 (8%)
Query: 18 DKDSKKNESSDKTE----RSYRKRDEIEDGTEEKRSKRRSS--GDGDDERVSKKDRDRDD 71
++D + N D+ R + DE+E +E+R +RR D DER ++DR+R+
Sbjct: 453 ERDRRDNRERDQRPSSPIRHQGRNDELE--RDERREERRVDRVDDRRDERARERDRERER 510
Query: 72 DRDKERHRSG-RDRDRDRDRDGERS-SRDRDRDREKDRDREKDR-REKEKERER-RERER 127
DR++ER R RDR+R+++R+ ER +R+R+R+REK+RDRE+DR R+ ++ERER RER+R
Sbjct: 511 DRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDR 570
Query: 128 EKERERERSRRSKSRS-ERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSE 186
EKERERER R + R ER+RE ER ERER R ER+R+R+ E++D+ R R R +
Sbjct: 571 EKEREREREERERERERERERERER-ERERERARERDKERERQRDWEDKDKGRDDR-REK 628
Query: 187 RDFEMRDSR 195
R+ E+R+ R
Sbjct: 629 RE-EIREDR 636
Score = 126 bits (316), Expect = 4e-28
Identities = 79/189 (41%), Positives = 115/189 (60%), Gaps = 17/189 (8%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKR--SKRRSSGDGD----DERVSKKDRDRDD 71
++D++ ER + +RD ++ ++R S R G D DER ++ DR D
Sbjct: 435 ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 494
Query: 72 DRDKERHRSGRDRDRDRDRDGERS---SRDRDRDREKDRDREKDR-REKEKERER---RE 124
DR ER R+RDR+R+RD ER R+RDR+REK+R+ E++R RE+E+ERE+ RE
Sbjct: 495 DRRDER---ARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 551
Query: 125 REREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSR 184
R+R+++ +RER R + E++RE EREERER R ER+RERER ER R R
Sbjct: 552 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERER-ERARERDKERE 610
Query: 185 SERDFEMRD 193
+RD+E +D
Sbjct: 611 RQRDWEDKD 619
Score = 123 bits (308), Expect = 3e-27
Identities = 74/191 (38%), Positives = 111/191 (57%), Gaps = 21/191 (10%)
Query: 23 KNESSDKTERSYRKR-DEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERH--- 78
+N+ ++ ER +R D ++D +E+ +R + D ER +++R+RD +R+KER
Sbjct: 475 RNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 534
Query: 79 ----------RSGRDRDRDRDRDGERS-SRDRDRDREKDRDREKDRREKEKERER---RE 124
RDR+RDRDRD +R R+R+RDREK+R+RE++ RE+E+ERER RE
Sbjct: 535 ERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 594
Query: 125 REREKERERERSR-RSKSRSERDREIEREERERSRRSI--SRSERDREREREERDRSRRS 181
RERE+ER RER + R + R D++ R++R R I R+ RD ER+ + R R
Sbjct: 595 RERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 654
Query: 182 RSRSERDFEMR 192
S S R R
Sbjct: 655 GSPSPRQSPKR 665
Score = 106 bits (264), Expect = 4e-22
Identities = 77/193 (39%), Positives = 105/193 (53%), Gaps = 18/193 (9%)
Query: 15 ELEDKDSKKN-ESSDKTERSYRKRDEI--EDGTEEKRSKRRSSGDGDDERVSKKDRD--- 68
+++ S N S +T SY +RD D ++ R G+ +R ++RD
Sbjct: 407 QIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRP 466
Query: 69 ----RDDDRDKERHRSGRDRDRDRDR-DGERSSRDRDRDREKDRDREKDRREKEKERERR 123
R R+ E R R +R DR D R R R+RDRE++RDRE RE+E+ERER
Sbjct: 467 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRE---RERERERER- 522
Query: 124 EREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE-ERDRSRRSR 182
+REREKERE ER R + ER++E +RE R+R R ER+RER+RE ER+R R R
Sbjct: 523 DREREKERELERERAREREREREKERDRE-RDRDRDHDRERERERERDREKEREREREER 581
Query: 183 SRSERDFEMRDSR 195
R ER+ E R
Sbjct: 582 ER-ERERERERER 593
Score = 103 bits (256), Expect = 3e-21
Identities = 62/182 (34%), Positives = 106/182 (58%), Gaps = 17/182 (9%)
Query: 10 EKTVEELEDK-DSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRS-----SGDGDDERVS 63
E+ V+ ++D+ D + E + ER + E E + +R K R + + + ER
Sbjct: 487 ERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREK 546
Query: 64 KKDRDRDDDRDKERHRSG-RDRDRDRDRDGERSSRDRDRDREKDRDREKDR-----REKE 117
++DR+RD DRD +R R R+RDR+++R+ ER R+R+R+RE++R+RE++R RE++
Sbjct: 547 ERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERD 606
Query: 118 KERERRE--REREKERERERSRRS---KSRSERDREIEREERERSRRSISRSERDRERER 172
KERER+ +++K R+ R +R + R+ RD ER+ ++R R S S R + R
Sbjct: 607 KERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR 666
Query: 173 EE 174
E
Sbjct: 667 RE 668
Score = 88.6 bits (218), Expect = 9e-17
Identities = 71/228 (31%), Positives = 101/228 (44%), Gaps = 42/228 (18%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEE-KRSKRRSSGDGDDERVSKKDRD 68
E + E+ ++ ++ S + +R R R + + E+ R R S D + D
Sbjct: 362 ESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSW 421
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDRE------------------ 110
ER R +RD+ RD R +RDR +R+R+
Sbjct: 422 ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELER 481
Query: 111 ---------------KDRREKEKERER---REREREKERERERSRRSKSRSERDREIERE 152
+D R +E++RER RERERE+ERER+R R + ER+R ERE
Sbjct: 482 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 541
Query: 153 ---ERERSRRSISRSERDRERERE-ERDRSR-RSRSRSERDFEMRDSR 195
E+ER R + DRERERE ERDR + R R R ER+ E R
Sbjct: 542 REREKERDRERDRDRDHDRERERERERDREKEREREREERERERERER 589
Score = 78.2 bits (191), Expect = 1e-13
Identities = 50/197 (25%), Positives = 94/197 (47%), Gaps = 13/197 (6%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRD-EIEDGTEEKRSKRRSSGDGDDERVSKKDRD 68
E+ E+ D++ ++ D+ R+RD E E E + +R + + ER +++R+
Sbjct: 541 EREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERE 600
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEK--------ER 120
R +RDKER R D+D+ RD R R+ R+ RD +R+ K++ R
Sbjct: 601 RARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPR 660
Query: 121 ERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERE----REERD 176
+ +R RE + + ++E+ R + + R + RS+S S +R+ E+R
Sbjct: 661 QSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRK 720
Query: 177 RSRRSRSRSERDFEMRD 193
R+ SR + E+++
Sbjct: 721 PERKESSRRYEEQELKE 737
Score = 74.3 bits (181), Expect = 2e-12
Identities = 71/223 (31%), Positives = 99/223 (43%), Gaps = 35/223 (15%)
Query: 7 EYLEKTVEELEDKDSKKN-ESSDKTERSYRKRDEIEDG-TEEKRSKRRSSGDGDDERVSK 64
+Y T E + +DS+ ++ D +R R ED EE RS R+ + R
Sbjct: 309 DYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEI 368
Query: 65 KDRDRDDDRDKERH-RSGRDRDR--DRDRDGERSSRDR---------------------- 99
++ R++ R + R+ R GR R R + G R SR
Sbjct: 369 RNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYP 428
Query: 100 DRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSE-RDREIEREERERSR 158
+RDR +RD R+ ER ER+R RER++ S R + R+ E+ER+ER R
Sbjct: 429 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 488
Query: 159 R----SISRSERDREREREERDRSR-RSRSRS-ERDFEMRDSR 195
R R ER RER+RE R+R R R R R ERD E R
Sbjct: 489 RVDRVDDRRDERARERDRE-RERDRERERERERERDREREKER 530
Score = 69.3 bits (168), Expect = 6e-11
Identities = 61/197 (30%), Positives = 87/197 (43%), Gaps = 15/197 (7%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKR--RSSGDGDDERVSKKDR 67
EK + E + ++ E + KRD +D EE+ ++ SS D D+R + R
Sbjct: 222 EKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 281
Query: 68 DRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKE----KERERR 123
DR D RD R RD RD R RD RD ++ RD R ++ ++RE R
Sbjct: 282 DRRDARDTRDRRELRD---SRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGR 338
Query: 124 EREREKERERERSR---RSKSRSERDR-EIEREERERSRRSI--SRSERDREREREERDR 177
+ R+++ E SR R+ R E R EI E R SR I R R R R E ++
Sbjct: 339 DTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEK 398
Query: 178 SRRSRSRSERDFEMRDS 194
R S+ D +S
Sbjct: 399 GSRGSRGSQIDSHSSNS 415
Score = 62.0 bits (149), Expect = 9e-09
Identities = 45/151 (29%), Positives = 63/151 (40%), Gaps = 5/151 (3%)
Query: 48 RSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGER---SSRDRDRDRE 104
RS R G D ER S+ R + R+ R + R++D +R+ E+ SSRD DRE
Sbjct: 217 RSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDRE 276
Query: 105 KDRDREKDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRS 164
R DRR+ R+RRE ++ R R SR ++ R+ R R
Sbjct: 277 PRDGR--DRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRD 334
Query: 165 ERDREREREERDRSRRSRSRSERDFEMRDSR 195
R+ R+E SRS SR
Sbjct: 335 REGRDTHRKEDTYPEESRSYGRNHLREESSR 365
Score = 59.3 bits (142), Expect = 6e-08
Identities = 54/181 (29%), Positives = 84/181 (45%), Gaps = 26/181 (14%)
Query: 22 KKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSG 81
K ++T +S+ +R E + T KR D E+ S+++R+ + D+ R
Sbjct: 223 KGRHDHERTSQSHDRRHERREDTRGKR---------DREKDSREEREYEQDQSSSRDH-- 271
Query: 82 RDRDRDRDRDGERSSRDRDRDREKDRDRE--KDRREKEKERERREREREKERERERSRRS 139
RD RDG RDR RD RDR +D R+ RE R+ R+ + R+ R S
Sbjct: 272 --RDDREPRDG----RDR-RDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRD-PRDS 323
Query: 140 KSRSERDREIEREERERSRRSISRSERD----REREREERDRSR-RSRSRSERDFEMRDS 194
+S + +RE R+ R+ + E R REE R+ R+ SR+E E+R+
Sbjct: 324 RSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRND 383
Query: 195 R 195
R
Sbjct: 384 R 384
Score = 59.3 bits (142), Expect = 6e-08
Identities = 42/146 (28%), Positives = 59/146 (39%), Gaps = 1/146 (0%)
Query: 51 RRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDRE 110
RRS+ +S R + R + R D +R +R D RDRE
Sbjct: 193 RRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDRE 252
Query: 111 KDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRER 170
KD RE+ + + + R+ +RE R RD RE R+ SR RD R
Sbjct: 253 KDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR 312
Query: 171 EREERDRSRRSRS-RSERDFEMRDSR 195
+ +E R SRS R D+ R+ R
Sbjct: 313 DTKESRDPRDSRSTRDAHDYRDREGR 338
Score = 58.5 bits (140), Expect = 1e-07
Identities = 43/182 (23%), Positives = 87/182 (47%), Gaps = 20/182 (10%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKE 76
EDKD +++ +K E R+ DG +E++SK+R +G R R+ D +
Sbjct: 616 EDKDKGRDDRREKREEIREDRNP-RDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSD 674
Query: 77 RHRSGRDRDR-----------DRDRDGERSSRDRDRD-REKDRDREKDRREKEK---ERE 121
+ SG D++ R S DR R K+ DR+ +R+E + E+E
Sbjct: 675 AYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQE 734
Query: 122 RREREREKERERERSRRSKSRSERDREI----EREERERSRRSISRSERDREREREERDR 177
+E+ +++RE++ +S R ++I + E+RE S R+ +++ + +++ + +
Sbjct: 735 LKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPKKK 794
Query: 178 SR 179
+
Sbjct: 795 KK 796
Score = 55.5 bits (132), Expect = 8e-07
Identities = 48/213 (22%), Positives = 85/213 (39%), Gaps = 31/213 (14%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVS 63
D + E+ EE E + ++ E + ER R+R D E++ G D+R
Sbjct: 569 DREKEREREREERERERERERERERERERE-RERARERDKERERQRDWEDKDKGRDDRRE 627
Query: 64 KKDRDRDDDRDKERH--RSGRDRDRDRDRDGERSSRDRDRDREKDRDREK---DRREKEK 118
K++ R+D ++ H R + R R+ R S R R+ D D D+ EK +
Sbjct: 628 KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHR 687
Query: 119 ---------------------ERERREREREKERERERSRRSKSRSERDREIEREERERS 157
+R+ R +E +++ ER+ S R E ++ +++R
Sbjct: 688 LLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQRE 747
Query: 158 RRSISRSERDRERE----REERDRSRRSRSRSE 186
+ I S R R ++ + DR R+ E
Sbjct: 748 QTEILESSRMRAQDIIGHHQSEDRETSDRAHDE 780
Score = 49.3 bits (116), Expect = 6e-05
Identities = 59/247 (23%), Positives = 102/247 (40%), Gaps = 62/247 (25%)
Query: 9 LEKTVEELEDKDSKKNESSDKTERSY---------RKRDEIEDGTEEKRSKRRSSGDGDD 59
L K+ + + K S K+ S+ K +R ++R+ + +++K + S
Sbjct: 37 LRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIP 96
Query: 60 ERVSK----KDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRD------------- 102
E ++ K++ + DR +E+ R G+DR RD +R +R RD+ R
Sbjct: 97 EDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFER--QREKRDKPRSTSPAGQHHSPISS 154
Query: 103 -REKDRDREKDRREKEKERERRER-----------------------------EREKERE 132
+ ++ RR+R +R++
Sbjct: 155 RHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPP 214
Query: 133 RERS-RRSKSRSERDREIEREERERSRRSISRSERDRERE-REERDRSR-RSRSRSER-D 188
R RS R K R + +R + +R RR +R +RDRE++ REER+ + +S SR R D
Sbjct: 215 RHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDD 274
Query: 189 FEMRDSR 195
E RD R
Sbjct: 275 REPRDGR 281
>ref|NP_067062.1| RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 132 bits (331), Expect = 7e-30
Identities = 87/208 (41%), Positives = 121/208 (57%), Gaps = 23/208 (11%)
Query: 5 EYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRS-----SGDGDD 59
E T ++LE++ KK + + E+ R+R+ + E+R + R + +
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK 339
Query: 60 ERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSS---RDRDRDREKDRDREKDR--- 113
ER +++RDRD DR KER R RDR+RDRDRD ERSS +DR R REK RDRE++R
Sbjct: 340 ERERERERDRDRDRTKERDRD-RDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERE 398
Query: 114 ----REKEKERER-REREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDR 168
RE+E+ERER RERERE+ERERER + K RDRE E EE RR + R R++
Sbjct: 399 REREREREREREREREREREREREREREKDKK----RDRE-EDEEDAYERRKLERKLREK 453
Query: 169 EREREERDRSRRSRSRSE-RDFEMRDSR 195
E +ER ++ R R + R++E R
Sbjct: 454 EAAYQERLKNWEIRERKKTREYEKEAER 481
Score = 130 bits (328), Expect = 2e-29
Identities = 79/201 (39%), Positives = 121/201 (59%), Gaps = 21/201 (10%)
Query: 1 MDFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDE 60
M+ D+ + + + + + D K E K E+ +R EIE +E+R + R +
Sbjct: 269 MEEDKRDLISREISKFRDTHKKLEEEKGKKEK---ERQEIE---KERRERERERERERER 322
Query: 61 RVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR---REKE 117
R +++R+R+ +R+KE+ R R+R+RDRDRD RDRDRDRE+DRDR+++R R K+
Sbjct: 323 REREREREREREREKEKERE-RERERDRDRD-RTKERDRDRDRERDRDRDRERSSDRNKD 380
Query: 118 KERER---REREREKERERERSRRSKSRSERDREIERE-ERERSRRSISRSERDRERERE 173
+ R R R+RERE+ERERER R + ER+RE ERE ERER R E+D++R+RE
Sbjct: 381 RSRSREKSRDRERERERERERERERERERERERERERERERERER------EKDKKRDRE 434
Query: 174 ERDRSRRSRSRSERDFEMRDS 194
E + R + ER +++
Sbjct: 435 EDEEDAYERRKLERKLREKEA 455
Score = 107 bits (267), Expect = 2e-22
Identities = 72/203 (35%), Positives = 114/203 (55%), Gaps = 14/203 (6%)
Query: 5 EYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSG---DGDDER 61
E E E+ E +++ ++ E + ER K E E E R + R+ D D ER
Sbjct: 306 EKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRER 365
Query: 62 VSKKDRDRDDDRDKERHRS---GRDRDRDRDRDGERS---SRDRDRDREKDRDREKDR-R 114
+DR+R DR+K+R RS RDR+R+R+R+ ER R+R+R+RE++R+RE++R R
Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERER 425
Query: 115 EKEKERERRERERE--KERERERSRRSKSRS--ERDREIEREERERSRRSISRSERDRER 170
EK+K+R+R E E + + R+ ER R K + ER + E ER+++R +ER+ ER
Sbjct: 426 EKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 485
Query: 171 EREERDRSRRSRSRSERDFEMRD 193
RE ++R + E + RD
Sbjct: 486 RREMAKEAKRLKEFLEDYDDDRD 508
Score = 95.1 bits (235), Expect = 9e-19
Identities = 68/181 (37%), Positives = 103/181 (56%), Gaps = 29/181 (16%)
Query: 25 ESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDR 84
E + E KRD I + SK R + +E KK+++R + +KER R+R
Sbjct: 262 EDINAIEMEEDKRDLIS----REISKFRDTHKKLEEEKGKKEKERQEI-EKER----RER 312
Query: 85 DRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSR-RSKSRS 143
+R+R+R+ ER R+R+R+RE++R++EK+R ERERE++R+R+R++ R + R
Sbjct: 313 ERERERERERREREREREREREREKEKER----------ERERERDRDRDRTKERDRDRD 362
Query: 144 -ERDREIERE-------ERERSRRSISRSERDRERERE-ERDRSRRSRSRSERDFEMRDS 194
ERDR+ +RE +R RSR ER+RERERE ER+R R ER+ E
Sbjct: 363 RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERE 422
Query: 195 R 195
R
Sbjct: 423 R 423
Score = 85.5 bits (210), Expect = 8e-16
Identities = 60/199 (30%), Positives = 107/199 (53%), Gaps = 17/199 (8%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER 61
D D + ++ + D+D + SSD+ + R R++ D E+ +R + + ER
Sbjct: 350 DRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERER 409
Query: 62 VSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDRE--------KDRDREKDR 113
+++R+R+ +R++ER R +D+ RDR+ D E + R +R+ ++R + +
Sbjct: 410 --ERERERERERERERERE-KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEI 466
Query: 114 REKEKERE-RREREREKERERERSRRSKSRSE--RDREIEREERERSRRS-ISRSERDRE 169
RE++K RE +E ERE+ER RE ++ +K E D + +R++ + R S + + RDRE
Sbjct: 467 RERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDRE 526
Query: 170 RERE--ERDRSRRSRSRSE 186
+E E ERDR R E
Sbjct: 527 KEMEADERDRKREKEELEE 545
Score = 76.6 bits (187), Expect = 3e-13
Identities = 68/269 (25%), Positives = 109/269 (40%), Gaps = 95/269 (35%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
E+ E+ +++ +++ D+T+ R RD D ++ +R S + D R +K RDR
Sbjct: 334 EREKEKERERERERDRDRDRTKERDRDRDRERDRDRDR--ERSSDRNKDRSRSREKSRDR 391
Query: 70 DDDRDKERHRSGRDRDRDRDRDGERS-SRDRDRDREKD--RDRE---------------- 110
+ +R++ER R R+R+R+R+R+ ER R+R+R+REKD RDRE
Sbjct: 392 ERERERERERE-REREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKL 450
Query: 111 -------------------KDRREKEKERERRE--------------------------- 124
K RE EKE ER E
Sbjct: 451 REKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDP 510
Query: 125 ------------REREKERERERSRRSKSRSE---------------RDREIEREERERS 157
R+REKE E + R + + E D E++R E+E
Sbjct: 511 KYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAE 570
Query: 158 RRSISRSERDREREREERDRSRRSRSRSE 186
RR + +++ E E EE ++ + R E
Sbjct: 571 RRRQPQIKQEPESEEEEEEKQEKEEKREE 599
Score = 72.0 bits (175), Expect = 9e-12
Identities = 60/260 (23%), Positives = 109/260 (41%), Gaps = 78/260 (30%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
++T E D+D +++ D+ S R +D + + +R + + ER +++R+R
Sbjct: 352 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 411
Query: 70 DDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRD-REKDR-----------REKE 117
+ +R++ER R R+R++D+ RD E D R+ +R REK+ RE++
Sbjct: 412 ERERERERERE-REREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK 470
Query: 118 KERE-RREREREKERERERSRRSKSRSE--------------------------RDREIE 150
K RE +E ERE+ER RE ++ +K E R++E+E
Sbjct: 471 KTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEME 530
Query: 151 REERERSRRS---------------------ISRSERDRER-----------------ER 172
+ER+R R + R E++ ER E+
Sbjct: 531 ADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEK 590
Query: 173 EERDRSRRSRSRSERDFEMR 192
+E++ R E + E +
Sbjct: 591 QEKEEKREEPMEEEEEPEQK 610
Score = 65.9 bits (159), Expect = 6e-10
Identities = 49/174 (28%), Positives = 83/174 (47%), Gaps = 8/174 (4%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVS 63
D YE K +L +K++ E E RK+ + E+ +RR + +R+
Sbjct: 439 DAYER-RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLK 497
Query: 64 KKDRDRDDDRDKERHRSGRD-RDRDRDRDGERSSRDRDRDREKDRDREKDRR-----EKE 117
+ D DDDRD ++ G + R RDR+ E + +RDR REK+ E +R +
Sbjct: 498 EFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPD 557
Query: 118 KERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERE 171
+ E + E+E ER R+ + + SE + E E++E+E R E + E++
Sbjct: 558 PDAELQRMEQEAERRRQPQIKQEPESEEEEE-EKQEKEEKREEPMEEEEEPEQK 610
>gb|AAF19255.1|AC004858_3 U1 small ribonucleoprotein 1SNRP homolog; match to PID:g4050087
[Homo sapiens]
Length = 784
Score = 132 bits (331), Expect = 7e-30
Identities = 87/208 (41%), Positives = 121/208 (57%), Gaps = 23/208 (11%)
Query: 5 EYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRS-----SGDGDD 59
E T ++LE++ KK + + E+ R+R+ + E+R + R + +
Sbjct: 221 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK 280
Query: 60 ERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSS---RDRDRDREKDRDREKDR--- 113
ER +++RDRD DR KER R RDR+RDRDRD ERSS +DR R REK RDRE++R
Sbjct: 281 ERERERERDRDRDRTKERDRD-RDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERE 339
Query: 114 ----REKEKERER-REREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDR 168
RE+E+ERER RERERE+ERERER + K RDRE E EE RR + R R++
Sbjct: 340 REREREREREREREREREREREREREREKDKK----RDRE-EDEEDAYERRKLERKLREK 394
Query: 169 EREREERDRSRRSRSRSE-RDFEMRDSR 195
E +ER ++ R R + R++E R
Sbjct: 395 EAAYQERLKNWEIRERKKTREYEKEAER 422
Score = 130 bits (328), Expect = 2e-29
Identities = 79/201 (39%), Positives = 121/201 (59%), Gaps = 21/201 (10%)
Query: 1 MDFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDE 60
M+ D+ + + + + + D K E K E+ +R EIE +E+R + R +
Sbjct: 210 MEEDKRDLISREISKFRDTHKKLEEEKGKKEK---ERQEIE---KERRERERERERERER 263
Query: 61 RVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR---REKE 117
R +++R+R+ +R+KE+ R R+R+RDRDRD RDRDRDRE+DRDR+++R R K+
Sbjct: 264 REREREREREREREKEKERE-RERERDRDRD-RTKERDRDRDRERDRDRDRERSSDRNKD 321
Query: 118 KERER---REREREKERERERSRRSKSRSERDREIERE-ERERSRRSISRSERDRERERE 173
+ R R R+RERE+ERERER R + ER+RE ERE ERER R E+D++R+RE
Sbjct: 322 RSRSREKSRDRERERERERERERERERERERERERERERERERER------EKDKKRDRE 375
Query: 174 ERDRSRRSRSRSERDFEMRDS 194
E + R + ER +++
Sbjct: 376 EDEEDAYERRKLERKLREKEA 396
Score = 107 bits (267), Expect = 2e-22
Identities = 72/203 (35%), Positives = 114/203 (55%), Gaps = 14/203 (6%)
Query: 5 EYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSG---DGDDER 61
E E E+ E +++ ++ E + ER K E E E R + R+ D D ER
Sbjct: 247 EKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRER 306
Query: 62 VSKKDRDRDDDRDKERHRS---GRDRDRDRDRDGERS---SRDRDRDREKDRDREKDR-R 114
+DR+R DR+K+R RS RDR+R+R+R+ ER R+R+R+RE++R+RE++R R
Sbjct: 307 DRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERER 366
Query: 115 EKEKERERRERERE--KERERERSRRSKSRS--ERDREIEREERERSRRSISRSERDRER 170
EK+K+R+R E E + + R+ ER R K + ER + E ER+++R +ER+ ER
Sbjct: 367 EKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 426
Query: 171 EREERDRSRRSRSRSERDFEMRD 193
RE ++R + E + RD
Sbjct: 427 RREMAKEAKRLKEFLEDYDDDRD 449
Score = 95.1 bits (235), Expect = 9e-19
Identities = 68/181 (37%), Positives = 103/181 (56%), Gaps = 29/181 (16%)
Query: 25 ESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDR 84
E + E KRD I + SK R + +E KK+++R + +KER R+R
Sbjct: 203 EDINAIEMEEDKRDLIS----REISKFRDTHKKLEEEKGKKEKERQEI-EKER----RER 253
Query: 85 DRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSR-RSKSRS 143
+R+R+R+ ER R+R+R+RE++R++EK+R ERERE++R+R+R++ R + R
Sbjct: 254 ERERERERERREREREREREREREKEKER----------ERERERDRDRDRTKERDRDRD 303
Query: 144 -ERDREIERE-------ERERSRRSISRSERDRERERE-ERDRSRRSRSRSERDFEMRDS 194
ERDR+ +RE +R RSR ER+RERERE ER+R R ER+ E
Sbjct: 304 RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERE 363
Query: 195 R 195
R
Sbjct: 364 R 364
Score = 85.5 bits (210), Expect = 8e-16
Identities = 60/199 (30%), Positives = 107/199 (53%), Gaps = 17/199 (8%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER 61
D D + ++ + D+D + SSD+ + R R++ D E+ +R + + ER
Sbjct: 291 DRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERER 350
Query: 62 VSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDRE--------KDRDREKDR 113
+++R+R+ +R++ER R +D+ RDR+ D E + R +R+ ++R + +
Sbjct: 351 --ERERERERERERERERE-KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEI 407
Query: 114 REKEKERE-RREREREKERERERSRRSKSRSE--RDREIEREERERSRRS-ISRSERDRE 169
RE++K RE +E ERE+ER RE ++ +K E D + +R++ + R S + + RDRE
Sbjct: 408 RERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDRE 467
Query: 170 RERE--ERDRSRRSRSRSE 186
+E E ERDR R E
Sbjct: 468 KEMEADERDRKREKEELEE 486
Score = 76.6 bits (187), Expect = 3e-13
Identities = 68/269 (25%), Positives = 109/269 (40%), Gaps = 95/269 (35%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
E+ E+ +++ +++ D+T+ R RD D ++ +R S + D R +K RDR
Sbjct: 275 EREKEKERERERERDRDRDRTKERDRDRDRERDRDRDR--ERSSDRNKDRSRSREKSRDR 332
Query: 70 DDDRDKERHRSGRDRDRDRDRDGERS-SRDRDRDREKD--RDRE---------------- 110
+ +R++ER R R+R+R+R+R+ ER R+R+R+REKD RDRE
Sbjct: 333 ERERERERERE-REREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKL 391
Query: 111 -------------------KDRREKEKERERRE--------------------------- 124
K RE EKE ER E
Sbjct: 392 REKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDP 451
Query: 125 ------------REREKERERERSRRSKSRSE---------------RDREIEREERERS 157
R+REKE E + R + + E D E++R E+E
Sbjct: 452 KYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAE 511
Query: 158 RRSISRSERDREREREERDRSRRSRSRSE 186
RR + +++ E E EE ++ + R E
Sbjct: 512 RRRQPQIKQEPESEEEEEEKQEKEEKREE 540
Score = 72.0 bits (175), Expect = 9e-12
Identities = 60/260 (23%), Positives = 109/260 (41%), Gaps = 78/260 (30%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
++T E D+D +++ D+ S R +D + + +R + + ER +++R+R
Sbjct: 293 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 352
Query: 70 DDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRD-REKDR-----------REKE 117
+ +R++ER R R+R++D+ RD E D R+ +R REK+ RE++
Sbjct: 353 ERERERERERE-REREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK 411
Query: 118 KERE-RREREREKERERERSRRSKSRSE--------------------------RDREIE 150
K RE +E ERE+ER RE ++ +K E R++E+E
Sbjct: 412 KTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEME 471
Query: 151 REERERSRRS---------------------ISRSERDRER-----------------ER 172
+ER+R R + R E++ ER E+
Sbjct: 472 ADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEK 531
Query: 173 EERDRSRRSRSRSERDFEMR 192
+E++ R E + E +
Sbjct: 532 QEKEEKREEPMEEEEEPEQK 551
Score = 65.9 bits (159), Expect = 6e-10
Identities = 49/174 (28%), Positives = 83/174 (47%), Gaps = 8/174 (4%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVS 63
D YE K +L +K++ E E RK+ + E+ +RR + +R+
Sbjct: 380 DAYER-RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLK 438
Query: 64 KKDRDRDDDRDKERHRSGRD-RDRDRDRDGERSSRDRDRDREKDRDREKDRR-----EKE 117
+ D DDDRD ++ G + R RDR+ E + +RDR REK+ E +R +
Sbjct: 439 EFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPD 498
Query: 118 KERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERE 171
+ E + E+E ER R+ + + SE + E E++E+E R E + E++
Sbjct: 499 PDAELQRMEQEAERRRQPQIKQEPESEEEEE-EKQEKEEKREEPMEEEEEPEQK 551
>gb|AAC97961.1| S164 [Homo sapiens]
Length = 735
Score = 132 bits (331), Expect = 7e-30
Identities = 87/208 (41%), Positives = 121/208 (57%), Gaps = 23/208 (11%)
Query: 5 EYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRS-----SGDGDD 59
E T ++LE++ KK + + E+ R+R+ + E+R + R + +
Sbjct: 172 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK 231
Query: 60 ERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSS---RDRDRDREKDRDREKDR--- 113
ER +++RDRD DR KER R RDR+RDRDRD ERSS +DR R REK RDRE++R
Sbjct: 232 ERERERERDRDRDRTKERDRD-RDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERE 290
Query: 114 ----REKEKERER-REREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDR 168
RE+E+ERER RERERE+ERERER + K RDRE E EE RR + R R++
Sbjct: 291 REREREREREREREREREREREREREREKDKK----RDRE-EDEEDAYERRKLERKLREK 345
Query: 169 EREREERDRSRRSRSRSE-RDFEMRDSR 195
E +ER ++ R R + R++E R
Sbjct: 346 EAAYQERLKNWEIRERKKTREYEKEAER 373
Score = 130 bits (328), Expect = 2e-29
Identities = 79/201 (39%), Positives = 121/201 (59%), Gaps = 21/201 (10%)
Query: 1 MDFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDE 60
M+ D+ + + + + + D K E K E+ +R EIE +E+R + R +
Sbjct: 161 MEEDKRDLISREISKFRDTHKKLEEEKGKKEK---ERQEIE---KERRERERERERERER 214
Query: 61 RVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR---REKE 117
R +++R+R+ +R+KE+ R R+R+RDRDRD RDRDRDRE+DRDR+++R R K+
Sbjct: 215 REREREREREREREKEKERE-RERERDRDRD-RTKERDRDRDRERDRDRDRERSSDRNKD 272
Query: 118 KERER---REREREKERERERSRRSKSRSERDREIERE-ERERSRRSISRSERDRERERE 173
+ R R R+RERE+ERERER R + ER+RE ERE ERER R E+D++R+RE
Sbjct: 273 RSRSREKSRDRERERERERERERERERERERERERERERERERER------EKDKKRDRE 326
Query: 174 ERDRSRRSRSRSERDFEMRDS 194
E + R + ER +++
Sbjct: 327 EDEEDAYERRKLERKLREKEA 347
Score = 107 bits (267), Expect = 2e-22
Identities = 72/203 (35%), Positives = 114/203 (55%), Gaps = 14/203 (6%)
Query: 5 EYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSG---DGDDER 61
E E E+ E +++ ++ E + ER K E E E R + R+ D D ER
Sbjct: 198 EKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRER 257
Query: 62 VSKKDRDRDDDRDKERHRS---GRDRDRDRDRDGERS---SRDRDRDREKDRDREKDR-R 114
+DR+R DR+K+R RS RDR+R+R+R+ ER R+R+R+RE++R+RE++R R
Sbjct: 258 DRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERER 317
Query: 115 EKEKERERRERERE--KERERERSRRSKSRS--ERDREIEREERERSRRSISRSERDRER 170
EK+K+R+R E E + + R+ ER R K + ER + E ER+++R +ER+ ER
Sbjct: 318 EKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 377
Query: 171 EREERDRSRRSRSRSERDFEMRD 193
RE ++R + E + RD
Sbjct: 378 RREMAKEAKRLKEFLEDYDDDRD 400
Score = 95.1 bits (235), Expect = 9e-19
Identities = 68/181 (37%), Positives = 103/181 (56%), Gaps = 29/181 (16%)
Query: 25 ESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDR 84
E + E KRD I + SK R + +E KK+++R + +KER R+R
Sbjct: 154 EDINAIEMEEDKRDLIS----REISKFRDTHKKLEEEKGKKEKERQEI-EKER----RER 204
Query: 85 DRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSR-RSKSRS 143
+R+R+R+ ER R+R+R+RE++R++EK+R ERERE++R+R+R++ R + R
Sbjct: 205 ERERERERERREREREREREREREKEKER----------ERERERDRDRDRTKERDRDRD 254
Query: 144 -ERDREIERE-------ERERSRRSISRSERDRERERE-ERDRSRRSRSRSERDFEMRDS 194
ERDR+ +RE +R RSR ER+RERERE ER+R R ER+ E
Sbjct: 255 RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERE 314
Query: 195 R 195
R
Sbjct: 315 R 315
Score = 85.5 bits (210), Expect = 8e-16
Identities = 60/199 (30%), Positives = 107/199 (53%), Gaps = 17/199 (8%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER 61
D D + ++ + D+D + SSD+ + R R++ D E+ +R + + ER
Sbjct: 242 DRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERER 301
Query: 62 VSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDRE--------KDRDREKDR 113
+++R+R+ +R++ER R +D+ RDR+ D E + R +R+ ++R + +
Sbjct: 302 --ERERERERERERERERE-KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEI 358
Query: 114 REKEKERE-RREREREKERERERSRRSKSRSE--RDREIEREERERSRRS-ISRSERDRE 169
RE++K RE +E ERE+ER RE ++ +K E D + +R++ + R S + + RDRE
Sbjct: 359 RERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDRE 418
Query: 170 RERE--ERDRSRRSRSRSE 186
+E E ERDR R E
Sbjct: 419 KEMEADERDRKREKEELEE 437
Score = 76.6 bits (187), Expect = 3e-13
Identities = 68/269 (25%), Positives = 109/269 (40%), Gaps = 95/269 (35%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
E+ E+ +++ +++ D+T+ R RD D ++ +R S + D R +K RDR
Sbjct: 226 EREKEKERERERERDRDRDRTKERDRDRDRERDRDRDR--ERSSDRNKDRSRSREKSRDR 283
Query: 70 DDDRDKERHRSGRDRDRDRDRDGERS-SRDRDRDREKD--RDRE---------------- 110
+ +R++ER R R+R+R+R+R+ ER R+R+R+REKD RDRE
Sbjct: 284 ERERERERERE-REREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKL 342
Query: 111 -------------------KDRREKEKERERRE--------------------------- 124
K RE EKE ER E
Sbjct: 343 REKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDP 402
Query: 125 ------------REREKERERERSRRSKSRSE---------------RDREIEREERERS 157
R+REKE E + R + + E D E++R E+E
Sbjct: 403 KYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAE 462
Query: 158 RRSISRSERDREREREERDRSRRSRSRSE 186
RR + +++ E E EE ++ + R E
Sbjct: 463 RRRQPQIKQEPESEEEEEEKQEKEEKREE 491
Score = 72.0 bits (175), Expect = 9e-12
Identities = 60/260 (23%), Positives = 109/260 (41%), Gaps = 78/260 (30%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
++T E D+D +++ D+ S R +D + + +R + + ER +++R+R
Sbjct: 244 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 303
Query: 70 DDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRD-REKDR-----------REKE 117
+ +R++ER R R+R++D+ RD E D R+ +R REK+ RE++
Sbjct: 304 ERERERERERE-REREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK 362
Query: 118 KERE-RREREREKERERERSRRSKSRSE--------------------------RDREIE 150
K RE +E ERE+ER RE ++ +K E R++E+E
Sbjct: 363 KTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEME 422
Query: 151 REERERSRRS---------------------ISRSERDRER-----------------ER 172
+ER+R R + R E++ ER E+
Sbjct: 423 ADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEK 482
Query: 173 EERDRSRRSRSRSERDFEMR 192
+E++ R E + E +
Sbjct: 483 QEKEEKREEPMEEEEEPEQK 502
Score = 65.9 bits (159), Expect = 6e-10
Identities = 49/174 (28%), Positives = 83/174 (47%), Gaps = 8/174 (4%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVS 63
D YE K +L +K++ E E RK+ + E+ +RR + +R+
Sbjct: 331 DAYER-RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLK 389
Query: 64 KKDRDRDDDRDKERHRSGRD-RDRDRDRDGERSSRDRDRDREKDRDREKDRR-----EKE 117
+ D DDDRD ++ G + R RDR+ E + +RDR REK+ E +R +
Sbjct: 390 EFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPD 449
Query: 118 KERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERE 171
+ E + E+E ER R+ + + SE + E E++E+E R E + E++
Sbjct: 450 PDAELQRMEQEAERRRQPQIKQEPESEEEEE-EKQEKEEKREEPMEEEEEPEQK 502
>emb|CAF96846.1| unnamed protein product [Tetraodon nigroviridis]
Length = 2196
Score = 131 bits (330), Expect = 9e-30
Identities = 75/185 (40%), Positives = 114/185 (61%), Gaps = 18/185 (9%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKE 76
+D+D +N+ D+ + +++D +D +EK R D D +R +KDRDRD ++K+
Sbjct: 1892 KDRDQDRNKEKDRDQDRNKEKDRDQDRNKEKDRDRSKEKDRDQDRNKEKDRDRDRSKEKD 1951
Query: 77 RHRSGRDRDRDRDRDGERS-------------SRDRDRDREKDRDREKDRREKEKERERR 123
R RS R+R+R R ++GER + RDRDRE+DRDR KD +E +R+RR
Sbjct: 1952 RERS-RERERSRGKEGERQRETEGERHRDQDGEKRRDRDRERDRDRTKDSDRREHDRDRR 2010
Query: 124 EREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRS 183
R+RE+ERER++ RR +SRS RDR+ +R +R+R R +RDR+R+R +RDR R
Sbjct: 2011 NRDRERERERDK-RRDRSRS-RDRDRDR-DRDRDRGKDRGRDRDRDRDR-DRDRDRERDK 2066
Query: 184 RSERD 188
+RD
Sbjct: 2067 DRDRD 2071
Score = 131 bits (330), Expect = 9e-30
Identities = 80/200 (40%), Positives = 124/200 (62%), Gaps = 25/200 (12%)
Query: 10 EKTVEELEDKDSKKNESSDKTE--RSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDR 67
EK + ++D + + SD+ E R R RD + +KR R S D D +DR
Sbjct: 1983 EKRRDRDRERDRDRTKDSDRREHDRDRRNRDRERERERDKRRDRSRSRDRD------RDR 2036
Query: 68 DRDDDRDKERHRSGRDRDRDRDRDGERS-SRDRDRDREKDRDREKDR---REKEKERER- 122
DRD DR K+R GRDRDRDRDRD +R RD+DRDR++D+DREKD+ REK+K+R+R
Sbjct: 2037 DRDRDRGKDR---GRDRDRDRDRDRDRDRERDKDRDRDRDKDREKDKDRDREKDKDRDRE 2093
Query: 123 ------REREREKERERERSRRSKSRSERDREIERE-ERERSRRSISRSERDRERERE-E 174
R+RE++K+RE+++ R + +RDRE +++ ++++ R ++D++R+RE +
Sbjct: 2094 KDKDKDRDREKDKDREKDKDRDREKDKDRDREKDKDRDKDKDREKDKDRDKDKDRDREKD 2153
Query: 175 RDRSRRSRSR-SERDFEMRD 193
+DR RR SR ++ E RD
Sbjct: 2154 KDRDRRDGSRGKDKREEKRD 2173
Score = 124 bits (311), Expect = 1e-27
Identities = 69/194 (35%), Positives = 117/194 (59%), Gaps = 18/194 (9%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDK- 75
+D+D +++ D+ R+R ++G ++ ++ D D E+ +DR+RD DR K
Sbjct: 1940 KDRDRDRSKEKDRERSRERERSRGKEGERQRETEGERHRDQDGEKRRDRDRERDRDRTKD 1999
Query: 76 ------ERHRSGRDRDRDRDRDGERS---SRDRDRDREKDRDREKDR-REKEKERER--- 122
+R R RDR+R+R+RD R SRDRDRDR++DRDR KDR R+++++R+R
Sbjct: 2000 SDRREHDRDRRNRDRERERERDKRRDRSRSRDRDRDRDRDRDRGKDRGRDRDRDRDRDRD 2059
Query: 123 REREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE-ERDRSRRS 181
R+RER+K+R+R+R + + +RDRE ++++R R +RDRE++++ E+D+ R
Sbjct: 2060 RDRERDKDRDRDRDKDREKDKDRDRE---KDKDRDREKDKDKDRDREKDKDREKDKDRDR 2116
Query: 182 RSRSERDFEMRDSR 195
+RD E R
Sbjct: 2117 EKDKDRDREKDKDR 2130
Score = 123 bits (308), Expect = 3e-27
Identities = 68/177 (38%), Positives = 110/177 (61%), Gaps = 11/177 (6%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDR 73
E DK ++ S D+ R RD +D ++ R D D ER +DRDRD DR
Sbjct: 2017 ERERDKRRDRSRSRDRDRDRDRDRDRGKDRGRDRDRDRDRDRDRDRERDKDRDRDRDKDR 2076
Query: 74 DKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR---REKEKERER-REREREK 129
+K++ R DR++D+DRD E+ +D+DRDREKD+DREKD+ REK+K+R+R ++++R+K
Sbjct: 2077 EKDKDR---DREKDKDRDREKD-KDKDRDREKDKDREKDKDRDREKDKDRDREKDKDRDK 2132
Query: 130 ERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSE 186
+++RE+ + +RDRE ++++R RR SR + RE +R++ S+ S +E
Sbjct: 2133 DKDREKDKDRDKDKDRDRE---KDKDRDRRDGSRGKDKREEKRDKHSSSKESEKTAE 2186
Score = 119 bits (298), Expect = 5e-26
Identities = 79/194 (40%), Positives = 112/194 (57%), Gaps = 26/194 (13%)
Query: 16 LEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDK 75
L D+ K S D+ R RD D + E+ R S + D ++ K++DRD DR+K
Sbjct: 1845 LWDRGQGKRWSRDRD----RSRDRDADRSRERERDRDRSKEKDRDQDRSKEKDRDQDRNK 1900
Query: 76 ERHRSGRDRDRDRDRDGERSS-RDRDRDREKDRD----REKDR---REKEKERERR---- 123
E+ R +DR++++DRD +R+ +DRDR +EKDRD +EKDR R KEK+RER
Sbjct: 1901 EKDRD-QDRNKEKDRDQDRNKEKDRDRSKEKDRDQDRNKEKDRDRDRSKEKDRERSRERE 1959
Query: 124 -------EREREKERERERSRRSKSRSERDREIEREE-RERSRRSISRSERDREREREER 175
ER+RE E ER R + + R +RDRE +R+ ++ RR R R+R+RERE
Sbjct: 1960 RSRGKEGERQRETEGERHRDQDGEKRRDRDRERDRDRTKDSDRREHDRDRRNRDRERERE 2019
Query: 176 DRSRRSRSRS-ERD 188
RR RSRS +RD
Sbjct: 2020 RDKRRDRSRSRDRD 2033
Score = 116 bits (290), Expect = 4e-25
Identities = 70/206 (33%), Positives = 120/206 (57%), Gaps = 22/206 (10%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER 61
D D EK E +++ + + ++ + +R +DG EKR R D D +
Sbjct: 1941 DRDRDRSKEKDRERSRERERSRGKEGERQRETEGERHRDQDG--EKRRDRDRERDRDRTK 1998
Query: 62 VS----------KKDRDRDDDRDKERHRS-GRDRDRDRDRDGERSSRDRDRDREKDRDRE 110
S +DR+R+ +RDK R RS RDRDRDRDRD +R +DR RDR++DRDR+
Sbjct: 1999 DSDRREHDRDRRNRDRERERERDKRRDRSRSRDRDRDRDRDRDRG-KDRGRDRDRDRDRD 2057
Query: 111 KDR-REKEKERER---REREREKERERERSRRSKSRSERDREIERE---ERERSRRSISR 163
+DR RE++K+R+R ++RE++K+R+RE+ + ++D++ +RE +RE+ +
Sbjct: 2058 RDRDRERDKDRDRDRDKDREKDKDRDREKDKDRDREKDKDKDRDREKDKDREKDKDRDRE 2117
Query: 164 SERDRERERE-ERDRSRRSRSRSERD 188
++DR+RE++ +RD+ + +RD
Sbjct: 2118 KDKDRDREKDKDRDKDKDREKDKDRD 2143
Score = 116 bits (290), Expect = 4e-25
Identities = 79/206 (38%), Positives = 118/206 (56%), Gaps = 23/206 (11%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
E+T E ED+ ++ + R+ R + + + ++ R D ER +DR +
Sbjct: 1821 ERTREASEDRRREREREAPHGGRALWDRGQGKRWSRDRDRSRDRDADRSRERERDRDRSK 1880
Query: 70 DDDRDKERHRS---GRDRDRDRDRDGERS---SRDRDRDREKDRDR--EKDR---REKEK 118
+ DRD++R + +DR++++DRD +R+ RD+DR++EKDRDR EKDR R KEK
Sbjct: 1881 EKDRDQDRSKEKDRDQDRNKEKDRDQDRNKEKDRDQDRNKEKDRDRSKEKDRDQDRNKEK 1940
Query: 119 ERER-REREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE---- 173
+R+R R +E+++ER RER R ER RE E ER R + R +RDRER+R+
Sbjct: 1941 DRDRDRSKEKDRERSRERERSRGKEGERQRETE-GERHRDQDGEKRRDRDRERDRDRTKD 1999
Query: 174 ----ERDRSRRSRSRSERDFEMRDSR 195
E DR RR+R R ER+ E RD R
Sbjct: 2000 SDRREHDRDRRNRDR-ERERE-RDKR 2023
Score = 110 bits (275), Expect = 2e-23
Identities = 57/164 (34%), Positives = 100/164 (60%), Gaps = 8/164 (4%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKER 77
D+D ++ D+ R RD D E+ R D D E+ +DR++D DRD+E+
Sbjct: 2035 DRDRDRDRGKDRGRDRDRDRDRDRDRDRERDKDRDRDRDKDREKDKDRDREKDKDRDREK 2094
Query: 78 HRSGRDRDRDRDRDGERSS-----RDRDRDREKDRDREKDR-REKEKERERREREREKER 131
+ +DRDR++D+D E+ +D+DRDREKD+DR+KD+ REK+K+R+ ++++R++E+
Sbjct: 2095 DKD-KDRDREKDKDREKDKDRDREKDKDRDREKDKDRDKDKDREKDKDRD-KDKDRDREK 2152
Query: 132 ERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREER 175
+++R RR SR + RE +R++ S+ S +E + E+
Sbjct: 2153 DKDRDRRDGSRGKDKREEKRDKHSSSKESEKTAESAKSVSSSEK 2196
Score = 82.0 bits (201), Expect = 8e-15
Identities = 55/173 (31%), Positives = 88/173 (50%), Gaps = 13/173 (7%)
Query: 35 RKRDEIEDGTEEKR-SKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGE 93
R+ E+ G R R + G + ++ R+ +DR +ER R R G+
Sbjct: 1791 REDTELHGGDRFARFESHREAASGSVQPSEERTREASEDRRREREREAPHGGRALWDRGQ 1850
Query: 94 RSSRDRDRDREKDRD------REKDR-REKEKERER---REREREKERERERSRRSKSRS 143
RDRDR +DRD RE+DR R KEK+R++ +E++R+++R +E+ R
Sbjct: 1851 GKRWSRDRDRSRDRDADRSRERERDRDRSKEKDRDQDRSKEKDRDQDRNKEKDRDQDRNK 1910
Query: 144 ERDREIEREERERSRRSISRSERDRERERE-ERDRSRRSRSRSERDFEMRDSR 195
E+DR+ +R +E+ R +RD++R +E +RDR R ER E SR
Sbjct: 1911 EKDRDQDR-NKEKDRDRSKEKDRDQDRNKEKDRDRDRSKEKDRERSRERERSR 1962
Score = 72.4 bits (176), Expect = 7e-12
Identities = 45/136 (33%), Positives = 70/136 (51%), Gaps = 10/136 (7%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER 61
D D +K E+ +D+D +K++ D+ + + RD +D EK R D D +R
Sbjct: 2065 DKDRDRDRDKDREKDKDRDREKDKDRDREKDKDKDRDREKDKDREKDKDRDREKDKDRDR 2124
Query: 62 VSKKDRDRD------DDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRRE 115
KDRD+D DRDK++ RDR++D+DRD SR +D+ RE+ RD+ +E
Sbjct: 2125 EKDKDRDKDKDREKDKDRDKDK---DRDREKDKDRDRRDGSRGKDK-REEKRDKHSSSKE 2180
Query: 116 KEKERERREREREKER 131
EK E + E+
Sbjct: 2181 SEKTAESAKSVSSSEK 2196
Score = 50.4 bits (119), Expect = 3e-05
Identities = 44/151 (29%), Positives = 65/151 (42%), Gaps = 30/151 (19%)
Query: 61 RVSKKDRDRDDD---RDKERHRSGRDRDRDRDRDGE-----------------RSSRDRD 100
R DR RDD R E R G D + G + S +R
Sbjct: 1764 RAQSPDRQRDDHWRRRSPEIRRRGSTNREDTELHGGDRFARFESHREAASGSVQPSEERT 1823
Query: 101 RDREKDRDREKDRREKEKERERREREREKE--RERERSRRSKSRSERDREIEREERERSR 158
R+ +DR RE++R R +R + K R+R+RSR +RD + R ERER R
Sbjct: 1824 REASEDRRREREREAPHGGRALWDRGQGKRWSRDRDRSR------DRDADRSR-ERERDR 1876
Query: 159 RSISRSERDRERERE-ERDRSRRSRSRSERD 188
+RD++R +E +RD+ R ++D
Sbjct: 1877 DRSKEKDRDQDRSKEKDRDQDRNKEKDRDQD 1907
Score = 40.8 bits (94), Expect = 0.021
Identities = 38/129 (29%), Positives = 55/129 (42%), Gaps = 8/129 (6%)
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERRERERE 128
R D++R R R + R G + D + R + RE + ER
Sbjct: 1764 RAQSPDRQRDDHWRRRSPEIRRRGSTNREDTELHGGDRFARFESHREAASGSVQPSEERT 1823
Query: 129 KE------RERERSRRSKSRSERDR-EIEREERERSRRSISRSERDREREREERDRSRRS 181
+E RERER R+ DR + +R R+R R ++R RERER +RDRS+
Sbjct: 1824 REASEDRRREREREAPHGGRALWDRGQGKRWSRDRDRSRDRDADRSRERER-DRDRSKEK 1882
Query: 182 RSRSERDFE 190
+R E
Sbjct: 1883 DRDQDRSKE 1891
Score = 38.1 bits (87), Expect = 0.14
Identities = 32/181 (17%), Positives = 72/181 (39%), Gaps = 13/181 (7%)
Query: 16 LEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKK-DRDRDDDRD 74
+++++S +NE DK + ED +K+ + +GD + V + + D + +
Sbjct: 2 VKNEESSENEEDDKDAAT-------EDHKGDKKKEECPVNEGDTKPVQPQAEMDSEQKNE 54
Query: 75 KERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERER-----REREREK 129
E G ++ D+D ++ D+ R + + K+K + + +
Sbjct: 55 HENKNDGEQMKKEADQDTDQDGADKTVGGSVKRGQLRTYVNKKKAATKNMTVVKAPANKT 114
Query: 130 ERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSERDF 189
+R R+KS + R+ + E D + + ++ D S S S S+ +
Sbjct: 115 STANKRETRAKSPQGSKKTQTRQRCADNDEEDEDEEEDDDDDDDDEDSSTSSSSESDSGY 174
Query: 190 E 190
+
Sbjct: 175 D 175
Score = 33.9 bits (76), Expect = 2.6
Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 3/96 (3%)
Query: 101 RDREKDRDREKDRREKEKERERREREREKERER---ERSRRSKSRSERDREIEREERERS 157
R + DR R+ R + E RR ++ E +R R +S E + ER+
Sbjct: 1764 RAQSPDRQRDDHWRRRSPEIRRRGSTNREDTELHGGDRFARFESHREAASGSVQPSEERT 1823
Query: 158 RRSISRSERDREREREERDRSRRSRSRSERDFEMRD 193
R + R+RERE R+ R + +R RD
Sbjct: 1824 REASEDRRREREREAPHGGRALWDRGQGKRWSRDRD 1859
Score = 33.9 bits (76), Expect = 2.6
Identities = 38/119 (31%), Positives = 45/119 (36%), Gaps = 21/119 (17%)
Query: 96 SRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRR---------SKSRSERD 146
S DR RD R + RR RE E R S R S+ R+
Sbjct: 1767 SPDRQRDDHWRRRSPEIRRRGSTNREDTELHGGDRFARFESHREAASGSVQPSEERTREA 1826
Query: 147 REIEREERER----------SRRSISRSERDRERERE-ERDRSR-RSRSRSERDFEMRD 193
E R ERER R R RDR+R R+ + DRSR R R R + RD
Sbjct: 1827 SEDRRREREREAPHGGRALWDRGQGKRWSRDRDRSRDRDADRSRERERDRDRSKEKDRD 1885
>ref|XP_635459.1| hypothetical protein DDB0219636 [Dictyostelium discoideum]
gi|60463784|gb|EAL61962.1| hypothetical protein
DDB0219636 [Dictyostelium discoideum]
Length = 2039
Score = 131 bits (329), Expect = 1e-29
Identities = 76/191 (39%), Positives = 117/191 (60%), Gaps = 15/191 (7%)
Query: 11 KTVEELEDKDS---KKNESSDKTERSYRKRDEIEDG-----TEEKRSKRRSSGDGDDERV 62
+T KDS SS T S RD I+D +E + S + + ER
Sbjct: 1299 QTTTTTSSKDSGTTTTTSSSTPTTTSSSNRDSIKDADMIDINDENNNNNNKSKEKEKERE 1358
Query: 63 SKKDRDRDDDRDKERHRSGRDRDRDRDRDGERS-SRDRDRDREKDRDREKDRREKEKERE 121
+K+R+++ +R+KER R R+++R+++++ ER R+R+R+REK+RDRE+++ E+E+ERE
Sbjct: 1359 REKEREKEKEREKERERE-REKEREKEKEKEREREREREREREKERDREREK-ERERERE 1416
Query: 122 R-REREREKERERERSRRSKSRSERDREIERE---ERERSRRSISRSERDREREREERDR 177
R RERERE+ERE+E+ + + ER+RE ERE ERER R ERDRE+ +ER+R
Sbjct: 1417 REREREREREREKEKEKEKEREREREREREREREREREREREREKEKERDREQREKERER 1476
Query: 178 SRRSRSRSERD 188
+R + R D
Sbjct: 1477 EQREKERDRSD 1487
Score = 125 bits (313), Expect = 9e-28
Identities = 62/170 (36%), Positives = 119/170 (69%), Gaps = 9/170 (5%)
Query: 15 ELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRD 74
++ D + + N +++K++ ++R+ ++ +EK ++ + + ER +K+++R+ +R+
Sbjct: 1335 DMIDINDENNNNNNKSKEKEKEREREKEREKEKEREKEREREREKEREKEKEKERERERE 1394
Query: 75 KERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERER-REREREKERER 133
+ER R ++RDR+R+++ ER R+R+R+RE++R+REK++ EKEKERER RERERE+ERER
Sbjct: 1395 RERERE-KERDREREKERERE-REREREREREREREKEK-EKEKERERERERERERERER 1451
Query: 134 ERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRS 183
ER R + E++R+ E+ E+ER R +R++ER+R +R+ + + +
Sbjct: 1452 EREREREREKEKERDREQREKER-----EREQREKERDRSDRNSDKNNNN 1496
Score = 122 bits (306), Expect = 6e-27
Identities = 74/194 (38%), Positives = 111/194 (57%), Gaps = 14/194 (7%)
Query: 11 KTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRD 70
K L+D S SS +T + +D GT S + R S KD D
Sbjct: 1281 KPKANLKDSKSPTTTSSTQTTTTTSSKDS---GTTTTTSSSTPTTTSSSNRDSIKDADMI 1337
Query: 71 DDRDKERHRSGRDRDRDRDRDGERS-SRDRDRDREKDRDREKDR-REKEKERER-RERER 127
D D+ + + + ++++++R+ E+ ++++R++E++R+REK+R +EKEKERER RERER
Sbjct: 1338 DINDENNNNNNKSKEKEKEREREKEREKEKEREKEREREREKEREKEKEKERERERERER 1397
Query: 128 EKERERERSRRSKSRSERDREIERE-ERERSRRSISRSERDRERERE-------ERDRSR 179
E+E+ER+R R + ER+RE ERE ERER + ER+RERERE ER+R R
Sbjct: 1398 EREKERDREREKEREREREREREREREREREKEKEKEKERERERERERERERERERERER 1457
Query: 180 RSRSRSERDFEMRD 193
ERD E R+
Sbjct: 1458 EREKEKERDREQRE 1471
Score = 118 bits (295), Expect = 1e-25
Identities = 78/245 (31%), Positives = 131/245 (52%), Gaps = 63/245 (25%)
Query: 11 KTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRD 70
K+ E+ ++++ +K +K R+R+ ++ +EK +R + + ER ++DR+R+
Sbjct: 1349 KSKEKEKEREREKEREKEKEREKEREREREKEREKEKEKEREREREREREREKERDRERE 1408
Query: 71 DDRDKERHRSGRDRDRDRDRDGERSS-----RDRDRDREKDRDREKDR-REKEKERERRE 124
+R++ER R R+R+R+R+R+ E+ R+R+R+RE++R+RE++R RE+EKE+ER
Sbjct: 1409 KERERERERE-REREREREREKEKEKEKEREREREREREREREREREREREREKEKERDR 1467
Query: 125 REREKERERERSRRSKSRSERD-----------------------------------REI 149
+REKERERE+ + + RS+R+ +EI
Sbjct: 1468 EQREKEREREQREKERDRSDRNSDKNNNNDGGGSGSSRSDKSSSKDSGSKKDQQTPRKEI 1527
Query: 150 ER-EERERSRRSISRS------------ERDRE------REREERDRSRRSRSRSERDFE 190
E+ E RE R S S ERD+E RE+E+RD+ R +R R RD
Sbjct: 1528 EKSESRENIRDSRSNDNNQSLSSSREIRERDKELKEKEQREKEQRDKDRENRERDNRD-- 1585
Query: 191 MRDSR 195
+RDSR
Sbjct: 1586 VRDSR 1590
Score = 102 bits (255), Expect = 5e-21
Identities = 67/238 (28%), Positives = 118/238 (49%), Gaps = 60/238 (25%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR 69
EK E ++++ ++ + +K + R+R+ + EK R + + ER +++R+R
Sbjct: 1364 EKEKEREKEREREREKEREKEKEKEREREREREREREKERDREREKERERERERERERER 1423
Query: 70 DDDRDKERHRSG-RDRDRDRDRDGERS-SRDRDRDREKDRDREKDRREKEKERERRERER 127
+ +R+KE+ + R+R+R+R+R+ ER R+R+R+REK+++R++++REKE+ERE+RE+ER
Sbjct: 1424 EREREKEKEKEKEREREREREREREREREREREREREKEKERDREQREKEREREQREKER 1483
Query: 128 --------------------------------------------EKERERERSRRSKSRS 143
EK RE R S+S
Sbjct: 1484 DRSDRNSDKNNNNDGGGSGSSRSDKSSSKDSGSKKDQQTPRKEIEKSESRENIRDSRSND 1543
Query: 144 ------------ERDREI-EREERERSRRSISRSERDREREREERDRSRRSRSRSERD 188
ERD+E+ E+E+RE+ +R R R+R+ R+ RD R ERD
Sbjct: 1544 NNQSLSSSREIRERDKELKEKEQREKEQRDKDRENRERD-NRDVRDSRNDQRGNQERD 1600
Score = 88.2 bits (217), Expect = 1e-16
Identities = 66/207 (31%), Positives = 100/207 (47%), Gaps = 18/207 (8%)
Query: 6 YEYLEKTVEELEDKDSKKNES----SDKTERSYRKRDEIEDGTEEK------RSKRRSSG 55
YE +E V +L+ +D K + S + R D+I T+ K +S +S
Sbjct: 1238 YENIENLVLKLKKRDELKTLAIRYHSLLEKEKPRMIDDIIKPTKPKANLKDSKSPTTTSS 1297
Query: 56 DGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR-R 114
S KD + +RD +D + + + + ++ +EK++ R
Sbjct: 1298 TQTTTTTSSKDSGTTTTTSSSTPTTTSSSNRDSIKDADMIDINDENNNNNNKSKEKEKER 1357
Query: 115 EKEKERERREREREKERERERSRRSKSRSERDREIERE-----ERERSRRSISRSERDRE 169
E+EKERE+ E+EREKERERER + + E++RE ERE E+ER R ER+RE
Sbjct: 1358 EREKEREK-EKEREKEREREREKEREKEKEKEREREREREREREKERDREREKERERERE 1416
Query: 170 RERE-ERDRSRRSRSRSERDFEMRDSR 195
RERE ER+R R E++ E R
Sbjct: 1417 REREREREREREKEKEKEKERERERER 1443
Score = 77.0 bits (188), Expect = 3e-13
Identities = 51/196 (26%), Positives = 102/196 (52%), Gaps = 20/196 (10%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKER 77
DK S K+ S K +++ RK E + E R R S+ + S++ R+RD + ++
Sbjct: 1507 DKSSSKDSGSKKDQQTPRKEIEKSESRENIRDSR-SNDNNQSLSSSREIRERDKELKEKE 1565
Query: 78 HRSGRDRDRDRDRDGERSSRD-RDRDREKDRDREKDRREKEKERERREREREKER----- 131
R RD+DR+ + ER +RD RD ++ ++E+D E ++ R+++++++E++R
Sbjct: 1566 QREKEQRDKDRE-NRERDNRDVRDSRNDQRGNQERDGGEPQQRRQQQQQQQERDRNDIRN 1624
Query: 132 -----------ERERSRRSKSRSERDREIEREERERSRRSISRSE-RDREREREERDRSR 179
++++ RR + RDR + R S +R++ R+R+ ++ RD +
Sbjct: 1625 QDNNNNDSQQQQQQQQRRQQDNDRRDRGNQDNINNRDNNSNNRNDNRERQPNQDNRDNNN 1684
Query: 180 RSRSRSERDFEMRDSR 195
+ +R+ER+ SR
Sbjct: 1685 NNSNRNERNDRNDSSR 1700
Score = 75.9 bits (185), Expect = 6e-13
Identities = 50/228 (21%), Positives = 105/228 (45%), Gaps = 38/228 (16%)
Query: 5 EYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSK 64
E E + E E + K+ E + ER + E E E +R + R D +
Sbjct: 1412 EREREREREREREREREKEKEKEKEREREREREREREREREREREREREKEKERDREQRE 1471
Query: 65 KDRDRDDDRDKERHRSGRDRDRDRDRDG-----ERSSRDRDRDREKDRDREKDRRE---- 115
K+R+R+ R+KER RS R+ D++ + DG RS + +D +D++ R+E
Sbjct: 1472 KEREREQ-REKERDRSDRNSDKNNNNDGGGSGSSRSDKSSSKDSGSKKDQQTPRKEIEKS 1530
Query: 116 ------------------------KEKERERREREREKERERERSRRSKSRSERD-REIE 150
+E+++E +E+E+ ++ +R++ R ++ R RD R+
Sbjct: 1531 ESRENIRDSRSNDNNQSLSSSREIRERDKELKEKEQREKEQRDKDRENRERDNRDVRDSR 1590
Query: 151 REERERSRRSISRSERDREREREERDRSR---RSRSRSERDFEMRDSR 195
++R R ++ R++++++++R R R++ + D + + +
Sbjct: 1591 NDQRGNQERDGGEPQQRRQQQQQQQERDRNDIRNQDNNNNDSQQQQQQ 1638
Score = 75.5 bits (184), Expect = 8e-13
Identities = 45/189 (23%), Positives = 96/189 (49%), Gaps = 7/189 (3%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDR 73
E + D S N S + R R+RD+ E++ ++R + ER ++ RD +D+
Sbjct: 1534 ENIRDSRSNDNNQSLSSSREIRERDKELKEKEQREKEQRDKDRENRERDNRDVRDSRNDQ 1593
Query: 74 DKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERER 133
+ R G + + R + ++ RDR+ R +D + ++++++++ R++ ++R
Sbjct: 1594 RGNQERDGGEPQQRRQQQQQQQERDRNDIRNQDNNNNDSQQQQQQQQRRQQDNDRRDRGN 1653
Query: 134 E-----RSRRSKSRSE-RDREIEREERERSRRSISRSER-DREREREERDRSRRSRSRSE 186
+ R S +R++ R+R+ ++ R+ + + +R+ER DR ER +R R+ S
Sbjct: 1654 QDNINNRDNNSNNRNDNRERQPNQDNRDNNNNNSNRNERNDRNDSSRERQDNRNERNDSR 1713
Query: 187 RDFEMRDSR 195
+ RD+R
Sbjct: 1714 ERQDTRDNR 1722
Score = 74.7 bits (182), Expect = 1e-12
Identities = 51/205 (24%), Positives = 101/205 (48%), Gaps = 20/205 (9%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSS-GDGDDERVSKKDRD 68
E+ E +K+ +++ + ER +R++ D ++ K ++ G G S K
Sbjct: 1452 EREREREREKEKERDREQREKEREREQREKERDRSDRNSDKNNNNDGGGSGSSRSDKSSS 1511
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKE-KERERRERE- 126
+D K++ ++ ++ R+ R SR D ++ RE R+KE KE+E+RE+E
Sbjct: 1512 KDSGSKKDQQTPRKEIEKSESRENIRDSRSNDNNQSLSSSREIRERDKELKEKEQREKEQ 1571
Query: 127 REKERE-RERSRR--------SKSRSERD-------REIEREERERSRRSI-SRSERDRE 169
R+K+RE RER R + ERD R+ +++++ER R I ++ + +
Sbjct: 1572 RDKDRENRERDNRDVRDSRNDQRGNQERDGGEPQQRRQQQQQQQERDRNDIRNQDNNNND 1631
Query: 170 REREERDRSRRSRSRSERDFEMRDS 194
+++++ + RR + RD +D+
Sbjct: 1632 SQQQQQQQQRRQQDNDRRDRGNQDN 1656
Score = 72.8 bits (177), Expect = 5e-12
Identities = 42/183 (22%), Positives = 93/183 (49%), Gaps = 16/183 (8%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRD--EIEDGTEEKRSKRRSSGDGDDER----VSKKDR 67
+EL++K+ ++ E DK +R R+RD ++ D ++R + G +R +++R
Sbjct: 1559 KELKEKEQREKEQRDK-DRENRERDNRDVRDSRNDQRGNQERDGGEPQQRRQQQQQQQER 1617
Query: 68 DRDDDRDKERHRSG--------RDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKE 119
DR+D R+++ + + + R +D DR +R ++D +R+ + + D RE++
Sbjct: 1618 DRNDIRNQDNNNNDSQQQQQQQQRRQQDNDR-RDRGNQDNINNRDNNSNNRNDNRERQPN 1676
Query: 120 RERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSR 179
++ R+ ER+ R+ S ER R R+ + +D++R+ ++ ++ +
Sbjct: 1677 QDNRDNNNNNSNRNERNDRNDSSRERQDNRNERNDSRERQDTRDNRKDQQRDNDKSNQVQ 1736
Query: 180 RSR 182
R+R
Sbjct: 1737 RNR 1739
Score = 63.2 bits (152), Expect = 4e-09
Identities = 36/190 (18%), Positives = 94/190 (48%), Gaps = 18/190 (9%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRD- 68
E+ ++ ++D+ N+S + ++ R++ + + RR G+ D+ ++ +D +
Sbjct: 1616 ERDRNDIRNQDNNNNDSQQQQQQQQRRQQD---------NDRRDRGNQDN--INNRDNNS 1664
Query: 69 --RDDDRDKERHRSGRDRDRDRDRDGERSSR-DRDRDREKDRDREKDRREKEKERERR-- 123
R+D+R+++ ++ RD + + ER+ R D R+R+ +R+ D RE++ R+ R
Sbjct: 1665 NNRNDNRERQPNQDNRDNNNNNSNRNERNDRNDSSRERQDNRNERNDSRERQDTRDNRKD 1724
Query: 124 -EREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSR 182
+R+ +K + +R+R S+ S + ++ + + + + ++ + ++
Sbjct: 1725 QQRDNDKSNQVQRNRDSQPSSRNSSPPHNQPQQHQSQQQQPQQLSPPIPQTDEEKFKNAK 1784
Query: 183 SRSERDFEMR 192
+ E FE +
Sbjct: 1785 KKREEKFESK 1794
Score = 57.8 bits (138), Expect = 2e-07
Identities = 38/196 (19%), Positives = 90/196 (45%), Gaps = 16/196 (8%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDR 73
+ + ++D+ N +D ER + + + R++R D ER ++ +R+D R
Sbjct: 1655 DNINNRDNNSNNRNDNRERQPNQDNRDNNNNNSNRNERNDRNDSSRERQDNRN-ERNDSR 1713
Query: 74 DKERHRSGR-DRDRDRD--------RDGERSSRDRDRDREKDRDREKDRREKEKERE--- 121
+++ R R D+ RD D RD + SSR+ + + + +++ ++
Sbjct: 1714 ERQDTRDNRKDQQRDNDKSNQVQRNRDSQPSSRNSSPPHNQPQQHQSQQQQPQQLSPPIP 1773
Query: 122 RREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRS 181
+ + E+ K +++R + +S+ + + EI++E + + ++S + + +
Sbjct: 1774 QTDEEKFKNAKKKREEKFESKQKNNNEIDQESPPNNNNNSNQSSNSNPSSNQSSRSNSKD 1833
Query: 182 RS---RSERDFEMRDS 194
RS ++ RD + R S
Sbjct: 1834 RSGGQQTPRDNQERQS 1849
Score = 52.8 bits (125), Expect = 5e-06
Identities = 25/128 (19%), Positives = 62/128 (47%), Gaps = 2/128 (1%)
Query: 20 DSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHR 79
+SK +T R ++R E+ + + D D++ K RD+ R K+
Sbjct: 1830 NSKDRSGGQQTPRDNQERQSGENNNNNNNNNNNTRDDHDNK--DKLKEMRDNIRKKQESN 1887
Query: 80 SGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRS 139
+ ++ +++ + + + + + + + + + ++ RE ++R+REKE E+E ++
Sbjct: 1888 NNQNNNQNNNNNNNNNHNNNNNNNNNNNNNNNNNNAPQENREDKKRDREKEEEKEDQKKR 1947
Query: 140 KSRSERDR 147
K++ R+R
Sbjct: 1948 KTQINRNR 1955
Score = 51.2 bits (121), Expect = 2e-05
Identities = 28/173 (16%), Positives = 70/173 (40%), Gaps = 4/173 (2%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRD- 68
E+ + + K +K ES K + + +S + R + KDR
Sbjct: 1777 EEKFKNAKKKREEKFESKQKNNNEIDQESPPNNNNNSNQSSNSNPSSNQSSRSNSKDRSG 1836
Query: 69 -RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERRERER 127
+ RD + +SG + + + + + ++RD +++K ++ + R+K++ + +
Sbjct: 1837 GQQTPRDNQERQSGENNNNNNNNNN--NTRDDHDNKDKLKEMRDNIRKKQESNNNQNNNQ 1894
Query: 128 EKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRR 180
+ + + + + + + +RDRE+E E+ D+ +R
Sbjct: 1895 NNNNNNNNNHNNNNNNNNNNNNNNNNNNAPQENREDKKRDREKEEEKEDQKKR 1947
Score = 49.7 bits (117), Expect = 5e-05
Identities = 26/176 (14%), Positives = 68/176 (37%), Gaps = 2/176 (1%)
Query: 9 LEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRD 68
+ +T EE KK E ++++ + E + +SS S +
Sbjct: 1772 IPQTDEEKFKNAKKKREEKFESKQKNNNEIDQESPPNNNNNSNQSSNSNPSSNQSSRSNS 1831
Query: 69 RDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRRE--KEKERERRERE 126
+D ++ R ++R + + ++ + RD ++D+ K+ R+ ++K+ +
Sbjct: 1832 KDRSGGQQTPRDNQERQSGENNNNNNNNNNNTRDDHDNKDKLKEMRDNIRKKQESNNNQN 1891
Query: 127 REKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSR 182
+ + + + + + +R ++ R+RE+EE ++ R
Sbjct: 1892 NNQNNNNNNNNNHNNNNNNNNNNNNNNNNNNAPQENREDKKRDREKEEEKEDQKKR 1947
Score = 42.7 bits (99), Expect = 0.006
Identities = 24/185 (12%), Positives = 80/185 (42%), Gaps = 16/185 (8%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKER 77
+ ++ N +++ T + +D++++ + R K+ S+ + ++ + + + + + + +
Sbjct: 1851 ENNNNNNNNNNNTRDDHDNKDKLKEMRDNIRKKQESNNNQNNNQNNNNNNNNNHNNNNNN 1910
Query: 78 HRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERR-------------- 123
+ + + + + + E + D+ RDREK+ ++E ++ K + R
Sbjct: 1911 NNNNNNNNNNNNAPQE-NREDKKRDREKEEEKEDQKKRKTQINRNRVGPSPPPQNLHPYQ 1969
Query: 124 -EREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSR 182
+ + + + S +++++++ R R+ +R+ RD
Sbjct: 1970 PPQHLQHPQHPQHPHHPMSHHHNQHHNQQQQQQQQHHGGFRGGRNDRNDRDVRDVRDERD 2029
Query: 183 SRSER 187
+R++R
Sbjct: 2030 NRNDR 2034
>emb|CAG06679.1| unnamed protein product [Tetraodon nigroviridis]
Length = 933
Score = 131 bits (329), Expect = 1e-29
Identities = 81/176 (46%), Positives = 115/176 (65%), Gaps = 20/176 (11%)
Query: 21 SKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRS 80
S+ S+ +ER R+ D D EE+R ++R +++R+RD +R+KE+ R
Sbjct: 496 SRYQGRSEDSEREERREDRRTDRAEERR----------EDRTRERERERDREREKEKERD 545
Query: 81 GRDRDRDRDRDGERS-SRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRS 139
R+R+R+++R+ ER +R+R+R+RE++R+RE RE+E+ERE RERERE ERERER R
Sbjct: 546 -REREREKEREAERERARERERERERERERE---REREREREERERERE-EREREREERE 600
Query: 140 KSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSERDFEMRDSR 195
+ R ER+RE ER ERE+ R R +RER REER R RR SR ER +RDSR
Sbjct: 601 RERKERERERER-EREQRERERQREWEERERGREER-RDRREDSRDER--SVRDSR 652
Score = 116 bits (291), Expect = 3e-25
Identities = 80/218 (36%), Positives = 113/218 (51%), Gaps = 33/218 (15%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKD--- 66
+++VE D+ + + S ++R + D + + + RR D R K
Sbjct: 427 DRSVERSNDRSATERSSDRGSDRDRYESDRRGEPSRDSSYDRRGGHGERDRRDRVKQYFY 486
Query: 67 ------------RDRDDDRDKERHRSGRDRDRDRDRDGERS-SRDRDRDREKDRDREKDR 113
+ R +D ++E R R DR +R +R+ R+R+RDRE+++++E+DR
Sbjct: 487 VFLYFPASPSRYQGRSEDSEREERREDRRTDRAEERREDRTRERERERDREREKEKERDR 546
Query: 114 -REKEKERERREREREKERERERSR-------RSKSRSERDREIEREERERSRRSISRSE 165
RE+EKERE ERER +ERERER R R + R ER+RE E ERER R R E
Sbjct: 547 EREREKEREA-ERERAREREREREREREREREREREREEREREREEREREREERERERKE 605
Query: 166 RDRERERE----ERDRSR----RSRSRSERDFEMRDSR 195
R+RERERE ER+R R R R R ER DSR
Sbjct: 606 REREREREREQRERERQREWEERERGREERRDRREDSR 643
Score = 102 bits (253), Expect = 8e-21
Identities = 59/194 (30%), Positives = 107/194 (54%), Gaps = 7/194 (3%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVS 63
++ E E+ + D+ ++ E + R R+ ++ ++ +R + + ER
Sbjct: 503 EDSEREERREDRRTDRAEERREDRTRERERERDREREKEKERDREREREKEREAERERAR 562
Query: 64 KKDRDRDDDRDKERHRSGRDRDRDRDR-DGERSSRDRDRDR-EKDRDREKDRREKEKERE 121
+++R+R+ +R++ER R +R+R+R + ER +R+R+R E++R+RE++R ++E+ER+
Sbjct: 563 EREREREREREREREREREREEREREREEREREREERERERKEREREREREREQRERERQ 622
Query: 122 RREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRS 181
R ERE+ RE R RR SR ER R++R+ R I DR+R R E S R+
Sbjct: 623 REWEERERGREERRDRREDSRDERSVRDSRDDRKMRRVFI----YDRKRMRVESSPSPRT 678
Query: 182 RSR-SERDFEMRDS 194
+ + RD DS
Sbjct: 679 TPKTAARDLSPADS 692
Score = 96.7 bits (239), Expect = 3e-19
Identities = 81/257 (31%), Positives = 107/257 (41%), Gaps = 77/257 (29%)
Query: 14 EELEDKDSKKNESSDKT-ERSYRKRDEIEDGTEEKRSKRRSSG--DGDDERVSKKDRDRD 70
E ++D +K+ DK ER ED +E RS R G D +R K R R
Sbjct: 342 ERERERDREKDRERDKERERDRSDTQRKEDTAQEDRSYGRGHGREDTKTDRAEKNGRVRG 401
Query: 71 DDRDKE-----------RHRSGRDRDRDRDRDGERSSRDRDRDREKDRDR---------- 109
+R+ RS RDR +R +RS+ +R DR DRDR
Sbjct: 402 SNRNSRGSQVEGGHDVWESRSSTARDRSVERSNDRSATERSSDRGSDRDRYESDRRGEPS 461
Query: 110 ------------EKDRREKEKE-------------------------------------- 119
E+DRR++ K+
Sbjct: 462 RDSSYDRRGGHGERDRRDRVKQYFYVFLYFPASPSRYQGRSEDSEREERREDRRTDRAEE 521
Query: 120 -RERREREREKERERERSRRSKSRSERDREIERE-ERERSRRSISRSERDRERERE-ERD 176
RE R RERE+ER+RER + + ER+RE ERE ERER+R ER+RERERE ER+
Sbjct: 522 RREDRTRERERERDREREKEKERDREREREKEREAERERARERERERERERERERERERE 581
Query: 177 RSRRSRSRSERDFEMRD 193
R R R R ER+ E +
Sbjct: 582 REEREREREEREREREE 598
Score = 78.2 bits (191), Expect = 1e-13
Identities = 58/189 (30%), Positives = 89/189 (46%), Gaps = 24/189 (12%)
Query: 31 ERSYRKRDEIEDGTEEKRSKR-----RSSGDGDDERVSKKD-RDRDDDRDKERHRSGRDR 84
ERS ++ D +E RSKR R D D E +S +D R D R+ R R+R
Sbjct: 248 ERSPPAQERRHDRRDETRSKREKDSIRDDRDYDSELLSSRDTRGERDTRESRDRRDARER 307
Query: 85 DRDRDRDGE---------------RSSRDR--DRDREKDRDREKDR-REKEKERERRERE 126
R+ RD RSSR+ R+RE++RDREKDR R+KE+ER+R + +
Sbjct: 308 GRETTRDSRDSRDAKDSRESRTDTRSSRESLGSRERERERDREKDRERDKERERDRSDTQ 367
Query: 127 REKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSRSRSE 186
R+++ +E + D + +R E+ R +R+ R + E RS + +
Sbjct: 368 RKEDTAQEDRSYGRGHGREDTKTDRAEKNGRVRGSNRNSRGSQVEGGHDVWESRSSTARD 427
Query: 187 RDFEMRDSR 195
R E + R
Sbjct: 428 RSVERSNDR 436
Score = 73.2 bits (178), Expect = 4e-12
Identities = 57/178 (32%), Positives = 81/178 (45%), Gaps = 21/178 (11%)
Query: 16 LEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDK 75
L + S+ +S + +R+ D R + R G+ ER R D RD+
Sbjct: 206 LSSRRSRSPLTSHEASSPHRRSDRSSPSHRHSRGRERFRGER--ERSPPAQERRHDRRDE 263
Query: 76 ERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDR--EKDRREKEKERERREREREKERER 133
R + R++D R RD D + RD E+D RE R+ RER RE R+
Sbjct: 264 TRSK--------REKDSIRDDRDYDSELLSSRDTRGERDTRESRDRRDARERGRETTRDS 315
Query: 134 ERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE---ERDRSR-RSRSRSER 187
SR +K E R + SR S+ ER+RER+RE ERD+ R R RS ++R
Sbjct: 316 RDSRDAKDSRE-----SRTDTRSSRESLGSRERERERDREKDRERDKERERDRSDTQR 368
Score = 72.4 bits (176), Expect = 7e-12
Identities = 53/165 (32%), Positives = 77/165 (46%), Gaps = 19/165 (11%)
Query: 22 KKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSG 81
++ S ER + +RDE T KR K D D + RD +RD R
Sbjct: 246 ERERSPPAQERRHDRRDE----TRSKREKDSIRDDRDYDSELLSSRDTRGERDTRESRDR 301
Query: 82 RDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRSKS 141
RD R+R R+ R SRD RD + R+ D R + RERERE++RE++R
Sbjct: 302 RDA-RERGRETTRDSRD-SRDAKDSRESRTDTRSSRESLGSRERERERDREKDR------ 353
Query: 142 RSERDREIEREERERSRRSISRSE-----RDREREREERDRSRRS 181
ERD+E ER+ + R+ + E R RE + DR+ ++
Sbjct: 354 --ERDKERERDRSDTQRKEDTAQEDRSYGRGHGREDTKTDRAEKN 396
Score = 72.4 bits (176), Expect = 7e-12
Identities = 73/282 (25%), Positives = 102/282 (35%), Gaps = 97/282 (34%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRD--EIEDGTEEKRSKRRSSGDGDDERVSKKDR 67
E+ E D+ + + T S RD + + + RS R S G + ER +++
Sbjct: 292 ERDTRESRDRRDARERGRETTRDSRDSRDAKDSRESRTDTRSSRESLGSRERERERDREK 351
Query: 68 DRDDDRDKERHRS--------------------------------GRDRDRDRDRDG--- 92
DR+ D+++ER RS GR R +R+ G
Sbjct: 352 DRERDKERERDRSDTQRKEDTAQEDRSYGRGHGREDTKTDRAEKNGRVRGSNRNSRGSQV 411
Query: 93 --------ERSSRDRDR---------------DREKDRDREK-------------DRREK 116
RSS RDR DR DRDR + DRR
Sbjct: 412 EGGHDVWESRSSTARDRSVERSNDRSATERSSDRGSDRDRYESDRRGEPSRDSSYDRRGG 471
Query: 117 EKERERRER-----------------------EREKERERERSRRSKSRSERDREIEREE 153
ER+RR+R + E+E RE R ++ R+ E
Sbjct: 472 HGERDRRDRVKQYFYVFLYFPASPSRYQGRSEDSEREERREDRRTDRAEERREDRTRERE 531
Query: 154 RERSRRSISRSERDREREREERDRSRRSRSRSERDFEMRDSR 195
RER R ERDRERERE+ + R R+R ER+ E R
Sbjct: 532 RERDREREKEKERDREREREKEREAERERAR-ERERERERER 572
Score = 68.2 bits (165), Expect = 1e-10
Identities = 51/183 (27%), Positives = 78/183 (41%), Gaps = 17/183 (9%)
Query: 22 KKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR-DDDRDKERH-- 78
++++ S + R R R+ E + D DE SK+++D DDRD +
Sbjct: 225 RRSDRSSPSHRHSRGRERFRGERERSPPAQERRHDRRDETRSKREKDSIRDDRDYDSELL 284
Query: 79 -----RSGRDRDRDRDR-DGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERE 132
R RD RDR D R+ RD RD + R + R RE +ERE
Sbjct: 285 SSRDTRGERDTRESRDRRDARERGRETTRDSRDSRDAKDSRESRTDTRSSRESLGSRERE 344
Query: 133 RERSRRSKSRSERDREIEREERERSR------RSISR--SERDREREREERDRSRRSRSR 184
RER R +++RE +R + +R RS R D + +R E++ R +R
Sbjct: 345 RERDREKDRERDKERERDRSDTQRKEDTAQEDRSYGRGHGREDTKTDRAEKNGRVRGSNR 404
Query: 185 SER 187
+ R
Sbjct: 405 NSR 407
Score = 67.8 bits (164), Expect = 2e-10
Identities = 59/190 (31%), Positives = 91/190 (47%), Gaps = 29/190 (15%)
Query: 12 TVEELEDKDSKKNESSD-KTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDR--- 67
++ + D DS+ S D + ER R+ + D E R R S D D + S++ R
Sbjct: 272 SIRDDRDYDSELLSSRDTRGERDTRESRDRRDARERGRETTRDSRDSRDAKDSRESRTDT 331
Query: 68 --DRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDR---REKEKERER 122
R+ +ER R RDR++DR+RD ER RDR + K+ ++DR R +E +
Sbjct: 332 RSSRESLGSRERERE-RDREKDRERDKER-ERDRSDTQRKEDTAQEDRSYGRGHGREDTK 389
Query: 123 REREREKERERERSR--------------RSKSRSERDREIER-EERERSRRSISRSERD 167
+R + R R +R S+S + RDR +ER +R + RS S+R
Sbjct: 390 TDRAEKNGRVRGSNRNSRGSQVEGGHDVWESRSSTARDRSVERSNDRSATERS---SDRG 446
Query: 168 REREREERDR 177
+R+R E DR
Sbjct: 447 SDRDRYESDR 456
Score = 62.0 bits (149), Expect = 9e-09
Identities = 51/205 (24%), Positives = 85/205 (40%), Gaps = 13/205 (6%)
Query: 4 DEYEYLEKTVEELED-----KDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGD 58
++++ EK+ E+ +D +D++K++ + S T +RS SG
Sbjct: 118 NKHKNKEKSEEKQKDGKDRGRDTEKHKEKKEKRSSPSPPRHRRSPTPRRRSTSSHSGSSA 177
Query: 59 DERVSKKDRDRDDDRDKERHRSGRDRD---RDRDRDGERSSRDRDRDREKDRDREKDRRE 115
+ R R R +G R R S R DR R
Sbjct: 178 QRHSTSPRRRRSSSPPYHRSVAGSASSPLSSRRSRSPLTSHEASSPHRRSDRSSPSHRHS 237
Query: 116 KEKERERREREREKE-RERERSRRSKSRSERDREIEREERERSRRSIS----RSERDRER 170
+ +ER R ERER +ER RR ++RS+R+++ R++R+ +S R ERD
Sbjct: 238 RGRERFRGERERSPPAQERRHDRRDETRSKREKDSIRDDRDYDSELLSSRDTRGERDTRE 297
Query: 171 EREERDRSRRSRSRSERDFEMRDSR 195
R+ RD R R + + RD++
Sbjct: 298 SRDRRDARERGRETTRDSRDSRDAK 322
Score = 60.1 bits (144), Expect = 3e-08
Identities = 58/166 (34%), Positives = 76/166 (44%), Gaps = 24/166 (14%)
Query: 49 SKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDR---DRDRD----------RDGERS 95
S RRS S R D RH GR+R +R+R RD RS
Sbjct: 207 SSRRSRSPLTSHEASSPHRRSDRSSPSHRHSRGRERFRGERERSPPAQERRHDRRDETRS 266
Query: 96 SRDRDRDREKDRDREKD---RREKEKERERRE-REREKERERERSRRSKSRSERDREIER 151
R++D R+ DRD + + R+ ER+ RE R+R RER R SR RD + R
Sbjct: 267 KREKDSIRD-DRDYDSELLSSRDTRGERDTRESRDRRDARERGRETTRDSRDSRDAKDSR 325
Query: 152 EERERSRRSISRSERDREREREERDRSR-RSRSR-SERDFEMRDSR 195
E R +R S S RERERE R R + R R ER+ + D++
Sbjct: 326 ESRTDTRSS-RESLGSRERERE---RDREKDRERDKERERDRSDTQ 367
Score = 49.3 bits (116), Expect = 6e-05
Identities = 52/218 (23%), Positives = 86/218 (38%), Gaps = 49/218 (22%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGD----------GDDERVSKKD 66
E K S + +S+ T+ S + G +K+ R S G + K+
Sbjct: 70 EKKGSVSSPASEATKSS-------KGGHSKKKGPRTPSPPPPVPLDIPVVGKKHKNKHKN 122
Query: 67 RDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREK-------DRREKEKE 119
+++ +++ K+ GRD ++ +++ +RSS R R R + ++
Sbjct: 123 KEKSEEKQKDGKDRGRDTEKHKEKKEKRSSPSPPRHRRSPTPRRRSTSSHSGSSAQRHST 182
Query: 120 RERREREREKERERE---------RSRRSKS------------RSERDREIEREERERSR 158
RR R R SRRS+S RS+R R R R R
Sbjct: 183 SPRRRRSSSPPYHRSVAGSASSPLSSRRSRSPLTSHEASSPHRRSDRSSPSHRHSRGRER 242
Query: 159 RSISRSERDREREREERDRSRRSRSRSERDFE-MRDSR 195
R ER+R +ER RR +RS+R+ + +RD R
Sbjct: 243 ---FRGERERSPPAQERRHDRRDETRSKREKDSIRDDR 277
Score = 33.5 bits (75), Expect = 3.4
Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 13/126 (10%)
Query: 15 ELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKR--------SKRRSSGDGDDERVSKKD 66
E E+++ + E D+ E S +R + D ++++ KR R + K
Sbjct: 624 EWEERERGREERRDRREDSRDERS-VRDSRDDRKMRRVFIYDRKRMRVESSPSPRTTPKT 682
Query: 67 RDRD-DDRDKERHRSGRD-RDRDR-DRDGERSSRDRDRDREKDRDREKDRREKEKERERR 123
RD D + + SG D RD DR D DGE S + E D E D + +++
Sbjct: 683 AARDLSPADSDGYNSGEDKRDDDRKDNDGE-SVASVGEEYEPISDDELDEILADSQKKED 741
Query: 124 EREREK 129
+++ EK
Sbjct: 742 QQDEEK 747
>gb|EAA16423.1| eukaryotic translation initiation factor 3 subunit 10 [Plasmodium
yoelii yoelii]
Length = 1268
Score = 130 bits (326), Expect = 3e-29
Identities = 78/177 (44%), Positives = 113/177 (63%), Gaps = 13/177 (7%)
Query: 28 DKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERHRSGRDRDRD 87
D +R + D+ EK+ ++ SG D ER ++DRDRD +RD++R R RDRDRD
Sbjct: 984 DNYKRHHENNDDHYRDASEKKDRKTWSGR-DRERDRERDRDRDRERDRDRDRE-RDRDRD 1041
Query: 88 RDRDGERS-------SRDRDRDREKDRDREKDRREKEKERER-REREREKERERERSRRS 139
RDR R S+DR+RDR+++RDRE+D RE+++ER+R RER+RE++R+RER R
Sbjct: 1042 RDRKYRREKEYRRDRSKDRERDRDRERDRERD-RERDRERDRDRERDRERDRDRERDRDR 1100
Query: 140 KSRSERDREIERE-ERERSRRSISRSERDREREREERDRSRRSRSRSERDFEMRDSR 195
+ +RDRE +RE +R+R R R ++D R+R ERDR R R ER+ D+R
Sbjct: 1101 ERERDRDRERDRERDRDRERGRDYRKDKDHRRDR-ERDRERDYRKDGERENRRGDTR 1156
Score = 123 bits (308), Expect = 3e-27
Identities = 76/187 (40%), Positives = 112/187 (59%), Gaps = 10/187 (5%)
Query: 17 EDKDSKKNESSDKTER-SYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDK 75
E+ D ++S+K +R ++ RD D ++ R D D ER +DRDR R+K
Sbjct: 991 ENNDDHYRDASEKKDRKTWSGRDRERDRERDRDRDRERDRDRDRERDRDRDRDRKYRREK 1050
Query: 76 ERHRSGRDRDRDRDRDGERS-SRDRDRDREKDRDREKDR-REKEKERER-REREREKERE 132
E +R R +DR+RDRD ER RDR+RDRE+DRDRE+DR R++++ER+R RERER+++RE
Sbjct: 1051 E-YRRDRSKDRERDRDRERDRERDRERDRERDRDRERDRERDRDRERDRDRERERDRDRE 1109
Query: 133 RERSR---RSKSRSERDREIEREERERSRRSISRSERDREREREERDRSR--RSRSRSER 187
R+R R R + R R + R +RER R R + +RE R + RS R + R +
Sbjct: 1110 RDRERDRDRERGRDYRKDKDHRRDRERDRERDYRKDGERENRRGDTRRSENDREKKRDKD 1169
Query: 188 DFEMRDS 194
D+ +S
Sbjct: 1170 DYTPNNS 1176
Score = 119 bits (298), Expect = 5e-26
Identities = 72/178 (40%), Positives = 107/178 (59%), Gaps = 14/178 (7%)
Query: 19 KDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKERH 78
+D +++ D+ R RD + ++ R+ + + R KDR+RD DR+++R
Sbjct: 1012 RDRERDRERDRDRDRERDRDRDRERDRDRDRDRKYRREKEYRRDRSKDRERDRDRERDRE 1071
Query: 79 RSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRR 138
R R+RDR+RDRD ER R+RDRDRE+DRDRE RE++++RE R+RER+++RER R R
Sbjct: 1072 RD-RERDRERDRDRERD-RERDRDRERDRDRE---RERDRDRE-RDRERDRDRERGRDYR 1125
Query: 139 SKSRSERDREIERE-------ERERSRRSISRSERDREREREERDRS-RRSRSRSERD 188
RDRE +RE ERE R RSE DRE++R++ D + S + ER+
Sbjct: 1126 KDKDHRRDRERDRERDYRKDGERENRRGDTRRSENDREKKRDKDDYTPNNSDNEKERN 1183
Score = 100 bits (250), Expect = 2e-20
Identities = 60/171 (35%), Positives = 90/171 (52%), Gaps = 11/171 (6%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER 61
D D ++ E D+D + +K R R +D D E+ +R D + +R
Sbjct: 1023 DRDRERDRDRDRERDRDRDRDRKYRREKEYRRDRSKDRERDRDRERDRERDRERDRERDR 1082
Query: 62 VSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERE 121
++DR+RD DR+++R R R+RDRDR+RD R+RDRDRE+ RD KD+ +
Sbjct: 1083 DRERDRERDRDRERDRDRE-RERDRDRERD-----RERDRDRERGRDYRKDKDHRRDRER 1136
Query: 122 RREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERER 172
RER+ K+ ERE R RSE DR E++R + + + D E+ER
Sbjct: 1137 DRERDYRKDGERENRRGDTRRSENDR-----EKKRDKDDYTPNNSDNEKER 1182
Score = 99.0 bits (245), Expect = 7e-20
Identities = 83/212 (39%), Positives = 114/212 (53%), Gaps = 28/212 (13%)
Query: 4 DEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRD-EIEDG----TEEKRSKRRS--SGD 56
+E E L K E + K+ + D+ R R+RD EIE EE RS +S
Sbjct: 905 EEEERLRKEEIERKKKEEAHKKKLDEISRIQRERDLEIEQQLLKQNEESRSGEKSLRKSS 964
Query: 57 GDDERVSKKDR----DRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKD 112
DDE ++ DDD K H + D RD E+ R R+++RDRE+D
Sbjct: 965 ADDEFTWRRHETGTSQYDDDNYKRHHENNDDHYRDAS---EKKDRKTWSGRDRERDRERD 1021
Query: 113 R-REKEKERER-REREREKERERE-------RSRRSKSRS-ERDREIERE-ERERSRRSI 161
R R++E++R+R RER+R+++R+R+ R RSK R +RDRE +RE +RER R
Sbjct: 1022 RDRDRERDRDRDRERDRDRDRDRKYRREKEYRRDRSKDRERDRDRERDRERDRERDRERD 1081
Query: 162 SRSERDRERERE-ERDRSR-RSRSRS-ERDFE 190
ERDRER+R+ ERDR R R R R ERD E
Sbjct: 1082 RDRERDRERDRDRERDRDRERERDRDRERDRE 1113
Score = 83.2 bits (204), Expect = 4e-15
Identities = 54/201 (26%), Positives = 100/201 (48%), Gaps = 27/201 (13%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER 61
D D EK KD +++ ++ R+RD D E+ +R + D +R
Sbjct: 1041 DRDRKYRREKEYRRDRSKDRERDRDRERDRERDRERDRERDRDRERDRERDRDRERDRDR 1100
Query: 62 VSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSS---RDRDRDREKDRDREKDRREKEK 118
+++RDRD +RD+E RDRDR+R RD + RDR+RDRE+D ++ +R +
Sbjct: 1101 --ERERDRDRERDRE-----RDRDRERGRDYRKDKDHRRDRERDRERDYRKDGERENRRG 1153
Query: 119 ERERREREREKERERERSRRSKSRSERDRE----------IEREERERSR-------RSI 161
+ R E +REK+R+++ + S +E++R IE +E +++ ++
Sbjct: 1154 DTRRSENDREKKRDKDDYTPNNSDNEKERNAWNIRNDDGGIESDENKKNNIEGDDNGNNL 1213
Query: 162 SRSERDREREREERDRSRRSR 182
++RD E+ ++ + + R
Sbjct: 1214 KGNKRDGEKNKDNENANNDKR 1234
Score = 59.7 bits (143), Expect = 4e-08
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 25/185 (13%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDR-------- 69
++D +++ D+ R+RD D E+ R D D ER ++DRDR
Sbjct: 1067 ERDRERDRERDRERDRDRERDRERDRDRERDRDRERERDRDRERDRERDRDRERGRDYRK 1126
Query: 70 ------DDDRDKERHRSGRDRDRDRDRDGERSSRDRD-RDREKDRDREKDRREKEKERER 122
D + RDR+RD +DGER +R D R E DR++++D+ +
Sbjct: 1127 DKDHRRDRE---------RDRERDYRKDGERENRRGDTRRSENDREKKRDKDDYTPNNSD 1177
Query: 123 REREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRSR 182
E+ER R +S + IE ++ + + ++ + ++ ++ E + +R
Sbjct: 1178 NEKERNAWNIRNDDGGIESDENKKNNIEGDDNGNNLKG-NKRDGEKNKDNENANNDKREE 1236
Query: 183 SRSER 187
E+
Sbjct: 1237 KGDEK 1241
Score = 53.5 bits (127), Expect = 3e-06
Identities = 52/207 (25%), Positives = 92/207 (44%), Gaps = 18/207 (8%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSD--KTERSYRKRDEIEDGTEE-KRSKRRSSGDGD 58
+F + E ++ VE +D +K K E+ R RD E + K + R + +
Sbjct: 847 EFTKSEMQQRIVEFEKDLKEQKERLHKLLKEEKIQRARDRREQHIRKLKAEEERKRREEE 906
Query: 59 DERVSKKDRDRDDDRDKERHRSGRDR----DRDRDRDGERSSRDRDRDREKDRDREKDRR 114
+ER+ K++ +R + +E H+ D R+RD + E+ + E+ R EK R
Sbjct: 907 EERLRKEEIERK--KKEEAHKKKLDEISRIQRERDLEIEQQLL---KQNEESRSGEKSLR 961
Query: 115 EKEKERE---RREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERDRERE 171
+ + E RR + + + +R ++ E+++R S ERDRER+
Sbjct: 962 KSSADDEFTWRRHETGTSQYDDDNYKRHHENNDDHYRDASEKKDRKTWSGRDRERDRERD 1021
Query: 172 RE---ERDRSRRSRSRSERDFEMRDSR 195
R+ ERDR R +RD + + R
Sbjct: 1022 RDRDRERDRDRDRERDRDRDRDRKYRR 1048
Score = 50.8 bits (120), Expect = 2e-05
Identities = 52/207 (25%), Positives = 89/207 (42%), Gaps = 24/207 (11%)
Query: 5 EYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSK 64
E ++ K + + +D++ K +K D E +EK + S D ++ S+
Sbjct: 794 ELSHMNKWIALIFQEDTEILLQEQKAVEEEKKAD-FEAALKEKEEYMKFSNDIEEFTKSE 852
Query: 65 KDR-----DRDDDRDKER-HRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEK 118
+ ++D KER H+ ++ R RD R R+ + E+ RRE+E+
Sbjct: 853 MQQRIVEFEKDLKEQKERLHKLLKEEKIQRARD-----RREQHIRKLKAEEERKRREEEE 907
Query: 119 ERERREREREKERERERSRR----SKSRSERDREIER------EERERSRRSISRSERDR 168
ER R+E K++E ++ S+ + ERD EIE+ EE +S+ +S D
Sbjct: 908 ERLRKEEIERKKKEEAHKKKLDEISRIQRERDLEIEQQLLKQNEESRSGEKSLRKSSADD 967
Query: 169 E--REREERDRSRRSRSRSERDFEMRD 193
E R E S+ +R E D
Sbjct: 968 EFTWRRHETGTSQYDDDNYKRHHENND 994
Score = 48.9 bits (115), Expect = 8e-05
Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 16/162 (9%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER 61
D D E+ + D+D ++ D+ R RD K R + D ER
Sbjct: 1081 DRDRERDRERDRDRERDRDRERERDRDRERDRERDRDRERGRDYRKDKDHRRDRERDRER 1140
Query: 62 VSKKDRDRDDDRDKERHRSGRDRDRDRDRDG---ERSSRDRDRD----REKDRDREKDRR 114
+KD +R++ R R RS DR++ RD+D S +++R+ R D E D
Sbjct: 1141 DYRKDGERENRRGDTR-RSENDREKKRDKDDYTPNNSDNEKERNAWNIRNDDGGIESDEN 1199
Query: 115 EKE--------KERERREREREKERERERSRRSKSRSERDRE 148
+K + +R+ EK ++ E + K + D +
Sbjct: 1200 KKNNIEGDDNGNNLKGNKRDGEKNKDNENANNDKREEKGDEK 1241
Score = 43.5 bits (101), Expect = 0.003
Identities = 32/143 (22%), Positives = 66/143 (45%), Gaps = 7/143 (4%)
Query: 2 DFDEYEYLEKTVEELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDER 61
D D E+ + +D +K++ + R+RD +DG E+ ++R + +++R
Sbjct: 1105 DRDRERDRERDRDRERGRDYRKDKDHRRDRERDRERDYRKDG--ERENRRGDTRRSENDR 1162
Query: 62 VSKKDRD----RDDDRDKERHR-SGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREK 116
K+D+D + D +KER+ + R+ D + D + + D + K EK
Sbjct: 1163 EKKRDKDDYTPNNSDNEKERNAWNIRNDDGGIESDENKKNNIEGDDNGNNLKGNKRDGEK 1222
Query: 117 EKERERREREREKERERERSRRS 139
K+ E ++ +E+ E+ + S
Sbjct: 1223 NKDNENANNDKREEKGDEKGQGS 1245
>gb|AAO30095.1| splicing factor-like protein [Arabidopsis thaliana]
Length = 527
Score = 129 bits (324), Expect = 5e-29
Identities = 83/184 (45%), Positives = 116/184 (62%), Gaps = 25/184 (13%)
Query: 1 MDFDEYEYLEKTVEELEDKDSKKNES-SDKTERSYRKRDEIE----DGTEEKRSKRRSS- 54
M+FDEYEYLEKTVEE + KK ES ++++ERSYRKR+ +E +G EE+R RS
Sbjct: 1 MEFDEYEYLEKTVEEGAGSNKKKEESGNERSERSYRKREGVERQGEEGGEEERVSSRSKK 60
Query: 55 --GDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKD 112
GDG++ K+DR+R ERHRS RD+DR+RD+ E S R+K+ DRE
Sbjct: 61 SRGDGEENGGGKRDRER------ERHRSSRDKDRERDKVREGS-------RDKESDRE-- 105
Query: 113 RREKEKERERREREREKERERERSRRSKSRSER-DREIEREERERSRRSISRSERDRERE 171
R KE++R R++ R++ER RER +RS SRS R ++E E ER R + E + + E
Sbjct: 106 RSSKERDRSDRDKPRDRER-REREKRSSSRSRREEKEPEVVERGSRRHRDKKDEPEADPE 164
Query: 172 REER 175
R++R
Sbjct: 165 RDQR 168
Score = 56.6 bits (135), Expect = 4e-07
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 28/124 (22%)
Query: 93 ERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRSKS----------- 141
E + ++ ++ + E+ R++E + E E+ER RS++S+
Sbjct: 15 EGAGSNKKKEESGNERSERSYRKREGVERQGEEGGEEERVSSRSKKSRGDGEENGGGKRD 74
Query: 142 ------RSERDREIERE-----------ERERSRRSISRSERDREREREERDRSRRSRSR 184
RS RD++ ER+ +RERS + RS+RD+ R+RE R+R +RS SR
Sbjct: 75 RERERHRSSRDKDRERDKVREGSRDKESDRERSSKERDRSDRDKPRDRERREREKRSSSR 134
Query: 185 SERD 188
S R+
Sbjct: 135 SRRE 138
Score = 50.4 bits (119), Expect = 3e-05
Identities = 37/102 (36%), Positives = 49/102 (47%), Gaps = 12/102 (11%)
Query: 100 DRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSE--------RDREIER 151
++ +E+ + +R +++E R+ E E ER SR KSR + RDRE
Sbjct: 20 NKKKEESGNERSERSYRKREGVERQGEEGGEEERVSSRSKKSRGDGEENGGGKRDRE--- 76
Query: 152 EERERSRRSISRSERDREREREERDRSRRSRSRSERDFEMRD 193
ER RS R R ERD+ RE S R RS ERD RD
Sbjct: 77 RERHRSSRDKDR-ERDKVREGSRDKESDRERSSKERDRSDRD 117
Score = 33.1 bits (74), Expect = 4.4
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 110 EKDRREKEKERERREREREKERERERSRRSKSRSE----RDREIEREERERSRRSISRSE 165
E + EK E ++++E ERS RS + E + E EER SR SR +
Sbjct: 5 EYEYLEKTVEEGAGSNKKKEESGNERSERSYRKREGVERQGEEGGEEERVSSRSKKSRGD 64
Query: 166 RDREREREERDRSRRSRSRSERD 188
+ E +RDR R R RS RD
Sbjct: 65 GE-ENGGGKRDRERE-RHRSSRD 85
>ref|XP_640578.1| hypothetical protein DDB0204606 [Dictyostelium discoideum]
gi|60468602|gb|EAL66605.1| hypothetical protein
DDB0204606 [Dictyostelium discoideum]
Length = 944
Score = 129 bits (324), Expect = 5e-29
Identities = 79/173 (45%), Positives = 113/173 (64%), Gaps = 17/173 (9%)
Query: 17 EDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRD-DDRDK 75
+D ++ N +++ E S + E+ T++ R R S D S +DRDRD D RD+
Sbjct: 126 DDDNNNNNNNNNNNETSNQPPKELNRDTKDHRCVDRDSRD------SYRDRDRDRDSRDR 179
Query: 76 ERHRSGR-DRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERER-REREREKERER 133
+R R R DRDRDRDR+ RDRDRDRE+DRDRE+DR +++++R+R RERER+++R+R
Sbjct: 180 DRDRDYRGDRDRDRDRE-----RDRDRDRERDRDRERDRGDRDRDRDRDRERERDRDRDR 234
Query: 134 ERSRRSKSRSERDREIEREERERSRRSISRSERDRERERE-ERDRSR-RSRSR 184
ER R + +RDRE ER +R+R R R RDR+R+R+ +RDR R R R R
Sbjct: 235 ERDRDRERDRDRDRERER-DRDRDYRDRDRDYRDRDRDRDRDRDRDRDRDRDR 286
Score = 125 bits (315), Expect = 5e-28
Identities = 74/165 (44%), Positives = 102/165 (60%), Gaps = 20/165 (12%)
Query: 18 DKDSKKNESSDKTER-SYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKE 76
++D+K + D+ R SYR RD D + R R GD D +R ++DRDRD +RD++
Sbjct: 150 NRDTKDHRCVDRDSRDSYRDRDRDRDSRDRDRD-RDYRGDRDRDRDRERDRDRDRERDRD 208
Query: 77 RHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERS 136
R R DRDRDRDRD ER RDRDRDRE+DRDRE+DR +R+RE+ER+R+R
Sbjct: 209 RERDRGDRDRDRDRDRERE-RDRDRDRERDRDRERDR----------DRDRERERDRDRD 257
Query: 137 RRSKSRSERDREIEREERERSRRSISRSERDREREREERDRSRRS 181
R + R RDR+ +R+ R+R R +RDR+R+R+ S S
Sbjct: 258 YRDRDRDYRDRDRDRD-RDRDR------DRDRDRDRDRYSSSSSS 295
Score = 105 bits (263), Expect = 5e-22
Identities = 68/158 (43%), Positives = 99/158 (62%), Gaps = 11/158 (6%)
Query: 38 DEIEDGTEEKRSKRRSSGDGDDERVSKK-DRDRDDDRDKERHRSGRDRDRDRDRDGERSS 96
D+I D + + ++ + + K+ +RD D R +R RDRDRDRD S
Sbjct: 121 DDINDDDDNNNNNNNNNNNETSNQPPKELNRDTKDHRCVDRDSRDSYRDRDRDRD----S 176
Query: 97 RDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERER 156
RDRDRDR+ DR++D R++E++R+ R+RER+++RER+R R + R +RDRE ER +R+R
Sbjct: 177 RDRDRDRDYRGDRDRD-RDRERDRD-RDRERDRDRERDRGDRDRDR-DRDRERER-DRDR 232
Query: 157 SRRSISRSERDRERERE-ERDRSRRSRSRSERDFEMRD 193
R ERDR+R+RE ERDR R R R +RD+ RD
Sbjct: 233 DRERDRDRERDRDRDRERERDRDRDYRDR-DRDYRDRD 269
Score = 94.0 bits (232), Expect = 2e-18
Identities = 60/191 (31%), Positives = 99/191 (51%), Gaps = 36/191 (18%)
Query: 18 DKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDRDKER 77
D+D ++ D+ R+RD D E R + R GD D +R ++R+RD DRD+ER
Sbjct: 178 DRDRDRDYRGDRDRDRDRERDRDRD-RERDRDRERDRGDRDRDRDRDRERERDRDRDRER 236
Query: 78 HRS---GRDRDRDRDRDGERSSRDRDRD-REKDRDREKDRREKEKERERREREREKERER 133
R RDRDR+R+RD +R RDRDRD R++DRDR++D R+R+++R+R
Sbjct: 237 DRDRERDRDRDRERERDRDRDYRDRDRDYRDRDRDRDRD------------RDRDRDRDR 284
Query: 134 ERSRRSKSRSER-------------------DREIEREERERSRRSISRSERDREREREE 174
+R R S S S ++++ R+I + + ++ +EE
Sbjct: 285 DRDRYSSSSSSAATIPSSTTTTNTNNEALPPPSSSSSSSKKKAPRTIDTLKDEFKQIQEE 344
Query: 175 RDRSRRSRSRS 185
R++ ++S + S
Sbjct: 345 REKDKKSTTSS 355
Score = 82.8 bits (203), Expect = 5e-15
Identities = 65/204 (31%), Positives = 97/204 (46%), Gaps = 36/204 (17%)
Query: 10 EKTVEELEDKDSKKNESSDKTERSYRKRDE---------IEDGTEEKRSKRRSSGDGDDE 60
+K +E + K K+N +K + E ++ GT D ++
Sbjct: 73 QKRKDESDSKLKKENSEINKVYNDFLSEHENKPTDTPKFVKGGTFILSDDINDDDDNNNN 132
Query: 61 RVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDRE-KDRDREKDRREKEKE 119
+ + + + KE +R +D R DRD S RDRDRDR+ +DRDR++D R
Sbjct: 133 NNNNNNNETSNQPPKELNRDTKDH-RCVDRDSRDSYRDRDRDRDSRDRDRDRDYRGD--- 188
Query: 120 RERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRS-----ERDRERERE- 173
R+R+R++ER+R+R R ERDR+ ER+R R R ERDR+R+RE
Sbjct: 189 ---RDRDRDRERDRDRDR------ERDRD---RERDRGDRDRDRDRDRERERDRDRDRER 236
Query: 174 ----ERDRSRRSRSRSERDFEMRD 193
ERDR R +RD + RD
Sbjct: 237 DRDRERDRDRDRERERDRDRDYRD 260
Score = 51.2 bits (121), Expect = 2e-05
Identities = 36/148 (24%), Positives = 60/148 (40%), Gaps = 9/148 (6%)
Query: 14 EELEDKDSKKNESSDKTERSYRKRDEIEDGTEEKRSKRRSSGDGDDERVSKKDRDRDDDR 73
E D+D + D+ R R+ D + R + R D D +R +DRDRD DR
Sbjct: 225 ERERDRDRDRERDRDRERDRDRDRERERDRDRDYRDRDRDYRDRDRDRDRDRDRDRDRDR 284
Query: 74 DKERHRSGRD---------RDRDRDRDGERSSRDRDRDREKDRDREKDRREKEKERERRE 124
D++R+ S + + + +K R D + E ++ + E
Sbjct: 285 DRDRYSSSSSSAATIPSSTTTTNTNNEALPPPSSSSSSSKKKAPRTIDTLKDEFKQIQEE 344
Query: 125 REREKERERERSRRSKSRSERDREIERE 152
RE++K+ S S S S + E + E
Sbjct: 345 REKDKKSTTSSSSTSLSSSSVEEETDEE 372
Score = 32.7 bits (73), Expect = 5.8
Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 10/88 (11%)
Query: 108 DREKDRREKEKERERREREREKERERERSRRSKSRSERDREIEREERERSRRSISRSERD 167
D D E + +E +R +K R ++R+ R+ R +RD
Sbjct: 122 DINDDDDNNNNNNNNNNNETSNQPPKELNRDTKDH----RCVDRDSRDSYR------DRD 171
Query: 168 REREREERDRSRRSRSRSERDFEMRDSR 195
R+R+ +RDR R R +RD + R
Sbjct: 172 RDRDSRDRDRDRDYRGDRDRDRDRERDR 199
>dbj|BAB09409.1| splicing factor-like protein [Arabidopsis thaliana]
Length = 604
Score = 128 bits (321), Expect = 1e-28
Identities = 83/184 (45%), Positives = 116/184 (62%), Gaps = 25/184 (13%)
Query: 1 MDFDEYEYLEKTVEELEDKDSKKNES-SDKTERSYRKRD----EIEDGTEEKRSKRRSS- 54
M+FDEYEYLEKTVEE + KK ES ++++ERSYRKR+ + E+G EE+R RS
Sbjct: 1 MEFDEYEYLEKTVEEGAGSNKKKEESGNERSERSYRKREGGERQGEEGGEEERVSSRSKK 60
Query: 55 --GDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKD 112
GDG++ K+DR+R ERHRS RD+DR+RD+ E S R+K+ DRE
Sbjct: 61 SRGDGEENGGGKRDRER------ERHRSSRDKDRERDKVREGS-------RDKESDRE-- 105
Query: 113 RREKEKERERREREREKERERERSRRSKSRSER-DREIEREERERSRRSISRSERDRERE 171
R KE++R R++ R++ER RER +RS SRS R ++E E ER R + E + + E
Sbjct: 106 RSSKERDRSDRDKPRDRER-REREKRSSSRSRREEKEPEVVERGSRRHRDKKDEPEADPE 164
Query: 172 REER 175
R++R
Sbjct: 165 RDQR 168
Score = 56.6 bits (135), Expect = 4e-07
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 28/124 (22%)
Query: 93 ERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRSKS----------- 141
E + ++ ++ + E+ R++E + E E+ER RS++S+
Sbjct: 15 EGAGSNKKKEESGNERSERSYRKREGGERQGEEGGEEERVSSRSKKSRGDGEENGGGKRD 74
Query: 142 ------RSERDREIERE-----------ERERSRRSISRSERDREREREERDRSRRSRSR 184
RS RD++ ER+ +RERS + RS+RD+ R+RE R+R +RS SR
Sbjct: 75 RERERHRSSRDKDRERDKVREGSRDKESDRERSSKERDRSDRDKPRDRERREREKRSSSR 134
Query: 185 SERD 188
S R+
Sbjct: 135 SRRE 138
Score = 50.4 bits (119), Expect = 3e-05
Identities = 37/102 (36%), Positives = 49/102 (47%), Gaps = 12/102 (11%)
Query: 100 DRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSE--------RDREIER 151
++ +E+ + +R +++E R+ E E ER SR KSR + RDRE
Sbjct: 20 NKKKEESGNERSERSYRKREGGERQGEEGGEEERVSSRSKKSRGDGEENGGGKRDRE--- 76
Query: 152 EERERSRRSISRSERDREREREERDRSRRSRSRSERDFEMRD 193
ER RS R R ERD+ RE S R RS ERD RD
Sbjct: 77 RERHRSSRDKDR-ERDKVREGSRDKESDRERSSKERDRSDRD 117
>ref|NP_568220.1| RNA recognition motif (RRM)-containing protein [Arabidopsis
thaliana] gi|15451046|gb|AAK96794.1| splicing
factor-like protein [Arabidopsis thaliana]
Length = 527
Score = 128 bits (321), Expect = 1e-28
Identities = 83/184 (45%), Positives = 116/184 (62%), Gaps = 25/184 (13%)
Query: 1 MDFDEYEYLEKTVEELEDKDSKKNES-SDKTERSYRKRD----EIEDGTEEKRSKRRSS- 54
M+FDEYEYLEKTVEE + KK ES ++++ERSYRKR+ + E+G EE+R RS
Sbjct: 1 MEFDEYEYLEKTVEEGAGSNKKKEESGNERSERSYRKREGGERQGEEGGEEERVSSRSKK 60
Query: 55 --GDGDDERVSKKDRDRDDDRDKERHRSGRDRDRDRDRDGERSSRDRDRDREKDRDREKD 112
GDG++ K+DR+R ERHRS RD+DR+RD+ E S R+K+ DRE
Sbjct: 61 SRGDGEENGGGKRDRER------ERHRSSRDKDRERDKVREGS-------RDKESDRE-- 105
Query: 113 RREKEKERERREREREKERERERSRRSKSRSER-DREIEREERERSRRSISRSERDRERE 171
R KE++R R++ R++ER RER +RS SRS R ++E E ER R + E + + E
Sbjct: 106 RSSKERDRSDRDKPRDRER-REREKRSSSRSRREEKEPEVVERGSRRHRDKKDEPEADPE 164
Query: 172 REER 175
R++R
Sbjct: 165 RDQR 168
Score = 56.6 bits (135), Expect = 4e-07
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 28/124 (22%)
Query: 93 ERSSRDRDRDREKDRDREKDRREKEKERERREREREKERERERSRRSKS----------- 141
E + ++ ++ + E+ R++E + E E+ER RS++S+
Sbjct: 15 EGAGSNKKKEESGNERSERSYRKREGGERQGEEGGEEERVSSRSKKSRGDGEENGGGKRD 74
Query: 142 ------RSERDREIERE-----------ERERSRRSISRSERDREREREERDRSRRSRSR 184
RS RD++ ER+ +RERS + RS+RD+ R+RE R+R +RS SR
Sbjct: 75 RERERHRSSRDKDRERDKVREGSRDKESDRERSSKERDRSDRDKPRDRERREREKRSSSR 134
Query: 185 SERD 188
S R+
Sbjct: 135 SRRE 138
Score = 50.4 bits (119), Expect = 3e-05
Identities = 37/102 (36%), Positives = 49/102 (47%), Gaps = 12/102 (11%)
Query: 100 DRDREKDRDREKDRREKEKERERREREREKERERERSRRSKSRSE--------RDREIER 151
++ +E+ + +R +++E R+ E E ER SR KSR + RDRE
Sbjct: 20 NKKKEESGNERSERSYRKREGGERQGEEGGEEERVSSRSKKSRGDGEENGGGKRDRE--- 76
Query: 152 EERERSRRSISRSERDREREREERDRSRRSRSRSERDFEMRD 193
ER RS R R ERD+ RE S R RS ERD RD
Sbjct: 77 RERHRSSRDKDR-ERDKVREGSRDKESDRERSSKERDRSDRD 117
Database: nr
Posted date: Jul 5, 2005 12:34 AM
Number of letters in database: 863,360,394
Number of sequences in database: 2,540,612
Lambda K H
0.305 0.127 0.324
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 317,963,781
Number of Sequences: 2540612
Number of extensions: 16299601
Number of successful extensions: 1093092
Number of sequences better than 10.0: 32093
Number of HSP's better than 10.0 without gapping: 18479
Number of HSP's successfully gapped in prelim test: 14544
Number of HSP's that attempted gapping in prelim test: 254539
Number of HSP's gapped (non-prelim): 276437
length of query: 195
length of database: 863,360,394
effective HSP length: 121
effective length of query: 74
effective length of database: 555,946,342
effective search space: 41140029308
effective search space used: 41140029308
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 71 (32.0 bits)
Medicago: description of AC137820.12