BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0340.11
(420 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
TRHY_HUMAN (Q07283) Trichohyalin 53 2e-06
IF2P_HUMAN (O60841) Eukaryotic translation initiation factor 5B ... 53 2e-06
MST2_DROHY (Q08696) Axoneme-associated protein mst101(2) 52 4e-06
M21_STRPY (P50468) M protein, serotype 2.1 precursor 51 6e-06
INCE_CHICK (P53352) Inner centromere protein 51 6e-06
TRHY_SHEEP (P22793) Trichohyalin 49 2e-05
SNXN_HUMAN (Q96L93) Kinesin-like motor protein C20orf23 (Sorting... 48 4e-05
PPG1_PIG (Q865B6) Peroxisome proliferator activated receptor gam... 48 5e-05
PPG1_HUMAN (Q9UBK2) Peroxisome proliferator activated receptor g... 48 5e-05
PPG1_BOVIN (Q865B7) Peroxisome proliferator activated receptor g... 48 5e-05
INCE_MOUSE (Q9WU62) Inner centromere protein 48 5e-05
TRHY_RABIT (P37709) Trichohyalin 47 7e-05
INCE_HUMAN (Q9NQS7) Inner centromere protein 47 7e-05
CALD_CHICK (P12957) Caldesmon (CDM) 47 9e-05
M18A_MOUSE (Q9JMH9) Myosin XVIIIA (Myosin 18A) (Myosin containin... 47 1e-04
YLX8_CAEEL (P46504) Hypothetical protein F23F12.8 in chromosome ... 46 2e-04
PLE1_HUMAN (Q15149) Plectin 1 (PLTN) (PCN) (Hemidesmosomal prote... 46 2e-04
FAU_DROME (Q9VGX3) Anoxia up-regulated protein 45 3e-04
ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog (X-li... 45 3e-04
PPG1_MOUSE (O70343) Peroxisome proliferator activated receptor g... 45 3e-04
>TRHY_HUMAN (Q07283) Trichohyalin
Length = 1898
Score = 52.8 bits (125), Expect = 2e-06
Identities = 52/211 (24%), Positives = 103/211 (48%), Gaps = 20/211 (9%)
Query: 129 ERIKRRTSEALREPKVRKKMAEHPRFH--SDKIKEKISYSL-----RRVWQERLKSKRFR 181
E++++ + LRE + +++ E R + K+++K L +R QER K R
Sbjct: 951 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 1010
Query: 182 EQIFLSWEQCIANAAKKGGCGQEELDWDSYNKIKEQL--ELQQLLQAEEKEKEKLMAIAR 239
E++ EQ + +K + +W+ + K++L E +QLL+ EE+EK +L R
Sbjct: 1011 EELQQEEEQLLREEREK----RRRQEWERQYRKKDELQQEEEQLLR-EEREKRRLQERER 1065
Query: 240 A----EKFIQSWSECLAKEAKKGGSGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKER 295
E+ Q + L +E + E E + E++Q+E L +R EK + +ER
Sbjct: 1066 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL--LREEPEKRRRQER 1123
Query: 296 ARTKAEKEARIKAIKKVMLNQKKKDLRERIK 326
R E+E + ++++ +++K R+ ++
Sbjct: 1124 ERQCREEEELQQEEEQLLREEREKRRRQELE 1154
Score = 48.5 bits (114), Expect = 3e-05
Identities = 59/283 (20%), Positives = 127/283 (44%), Gaps = 25/283 (8%)
Query: 91 ESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVRKKMAE 150
+ L RK +ER + + R + R+ E RE+ RR E RE ++R++ E
Sbjct: 304 QQLRRKQEEERREQ------QEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 151 HPR---FHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEELD 207
R ++ +E+ LRR +E + ++ R + L EQ + + +++L
Sbjct: 358 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR--REQQLR 415
Query: 208 WDSYNKIKEQLELQQLLQAEEK-EKEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKELD 266
+ + ++QL +Q L+ E++ +E+ + + E+ + E +E + E+ D
Sbjct: 416 REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRD 475
Query: 267 W---DSYEKIQEEMFLLNQIRRTTE--------KAKAKERARTKAEKEARIKAIKKVMLN 315
W + + E+ Q++R E K + +ER + +E +++ ++
Sbjct: 476 WLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERRE 535
Query: 316 Q--KKKDLRERIKGRGNIKSQLCKNANEDGEAALEITQQFKLD 356
Q K+++ ER++ R + QL + E E L+ ++ +L+
Sbjct: 536 QRLKRQEEEERLQQRLRSEQQLRREQEERLEQLLKREEEKRLE 578
Score = 40.0 bits (92), Expect = 0.011
Identities = 54/238 (22%), Positives = 104/238 (43%), Gaps = 15/238 (6%)
Query: 89 EIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVRKKM 148
E E L R+ ++R R+ + K + K + E E KRR E RE K R++
Sbjct: 956 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE--KRRRQE--REKKYREE- 1010
Query: 149 AEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEELDW 208
E + ++E+ R+ W+ + + K +++ EQ + +K + E +
Sbjct: 1011 EELQQEEEQLLREEREKRRRQEWERQYRKK---DELQQEEEQLLREEREKRRLQERERQY 1067
Query: 209 DSYNKIKEQLELQQLLQAEEKEKEKLMAIARA----EKFIQSWSECLAKEAKKGGSGEKE 264
+++++ E QLL EE+E + + R E+ Q + L +E +K E+E
Sbjct: 1068 REEEELQQEEE--QLL-GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERE 1124
Query: 265 LDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDLR 322
E++Q+E L + R + + ER + E+ R K ++ ++ DL+
Sbjct: 1125 RQCREEEELQQEEEQLLREEREKRRRQELERQYREEEELQRQKRKQRYRDEDQRSDLK 1182
Score = 37.7 bits (86), Expect = 0.056
Identities = 50/243 (20%), Positives = 110/243 (44%), Gaps = 23/243 (9%)
Query: 119 KGRKHSAETRERIKRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSK 178
KGR+ + R + R + E + RK+ R +K++E+ R + +E + +
Sbjct: 221 KGREEKQQQRRERQDRVFQEEEEKEWRKRETVL-RKEEEKLQEEEPQRQRELQEEEEQLR 279
Query: 179 RFREQIFLSWEQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIA 238
+ Q L E+ QEE + ++QL +Q + E+++E+
Sbjct: 280 KLERQE-LRRER------------QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 239 RAEKFIQSWSECLAKEAKKGGSGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERART 298
R E+ + + L +E ++ E++L + E+ +E+ Q+RR E+ + +++ R
Sbjct: 327 RREQQEERREQQLRREQEE--RREQQLRREQEEERREQ-----QLRREQEEERREQQLRR 379
Query: 299 KAEKEARIKAIKKVMLNQKKKDLRERIKGRGNIKSQLCKNANEDGEAALEITQQFKLDTK 358
+ E+E R + +++ ++++ LR + R + QL + E L QQ + + +
Sbjct: 380 EQEEERREQQLRREQQLRREQQLRREQQLRR--EQQLRREQQLRREQQLRREQQLRREQQ 437
Query: 359 LTK 361
L +
Sbjct: 438 LRR 440
Score = 36.6 bits (83), Expect = 0.12
Identities = 41/218 (18%), Positives = 95/218 (42%), Gaps = 13/218 (5%)
Query: 119 KGRKHSAETRERIKRRTSEAL-REPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKS 177
+GR+ +E E L R + ++ E D+ + + + W+ +L+
Sbjct: 838 RGRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRQEQRRDQKWRWQLEE 897
Query: 178 KRFREQIFLSWEQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAI 237
+R R + L + + QE+L + +E+ ELQ+ + + + +E+
Sbjct: 898 ERKRRRHTLYAKPAL----------QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQY 947
Query: 238 ARAEKFIQSWSECLAKEAKKGGSGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERAR 297
E+ Q + L +E +K E+E + +K+Q++ L + EK + +ER +
Sbjct: 948 REEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL--LGEEPEKRRRQEREK 1005
Query: 298 TKAEKEARIKAIKKVMLNQKKKDLRERIKGRGNIKSQL 335
E+E + ++++ +++K R+ + + K +L
Sbjct: 1006 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1043
Score = 35.4 bits (80), Expect = 0.28
Identities = 44/213 (20%), Positives = 95/213 (43%), Gaps = 17/213 (7%)
Query: 126 ETRERIKRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIF 185
+ R+R K R E L + + RK + E R ++ ++ + + +ER + ++ R++ F
Sbjct: 1314 QERDR-KFREEELLHQEQGRKFLEEEQRLREERERKFLKEEQQLRLEEREQLRQDRDRKF 1372
Query: 186 LSWEQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQAE-------------EKEKE 232
EQ ++ + +EE + ++ LE +Q L+ E E+E++
Sbjct: 1373 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1432
Query: 233 KLMAIARAEKFIQSWSECLAKEAKKGGSGEKELDWDSYEK--IQEEMFLLNQIRRTTEKA 290
+L R KF++ + L ++ + E+EL E+ ++EE L Q R+
Sbjct: 1433 QLHRQERDRKFLEE-EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ 1491
Query: 291 KAKERARTKAEKEARIKAIKKVMLNQKKKDLRE 323
+ ++ R + ++ R +K ++ + RE
Sbjct: 1492 EEQQLRRQERGQQRRQDRDRKFREEEQLRQERE 1524
Score = 32.7 bits (73), Expect = 1.8
Identities = 33/197 (16%), Positives = 84/197 (41%), Gaps = 51/197 (25%)
Query: 132 KRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQC 191
++R + RE +++++ E + +E+ L+R +ERL+ + RE++
Sbjct: 574 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEV------- 626
Query: 192 IANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECL 251
+++++ + L+ EE E+E+ + ++E+ + E L
Sbjct: 627 --------------------ERLEQEERRDERLKREEPEEERRHELLKSEEQEERRHEQL 666
Query: 252 AKEAKKGGSGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKK 311
+E ++ +++R E+ + ++R + + E+E R ++
Sbjct: 667 RREQQERRE--------------------QRLKREEEEERLEQRLKREHEEERR----EQ 702
Query: 312 VMLNQKKKDLRERIKGR 328
+ ++++ RERIK R
Sbjct: 703 ELAEEEQEQARERIKSR 719
Score = 32.3 bits (72), Expect = 2.3
Identities = 43/206 (20%), Positives = 91/206 (43%), Gaps = 22/206 (10%)
Query: 128 RERIKRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQI--- 184
RE+ +RR +A R +++ E K +++ S +++ +E + KR R++
Sbjct: 1237 REQERRRWQQANRHFPEEEQL-EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRK 1295
Query: 185 FLSWEQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFI 244
F EQ + ++ QE K +E+ L Q + E+E+ + R KF+
Sbjct: 1296 FREEEQLLQEREEQPLLRQER-----DRKFREEELLHQEQGRKFLEEEQRLREERERKFL 1350
Query: 245 QSWSECLAKEAKKGGSGEKELDWDSYEKIQEEMFLLNQ------IRRTTEKAKAKERART 298
+ + +E ++L D K +EE L++ R ++ + +ER R
Sbjct: 1351 KEEQQLRLEE-------REQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERK 1403
Query: 299 KAEKEARIKAIKKVMLNQKKKDLRER 324
E+E +++ + ++++ L+ER
Sbjct: 1404 FLEEEQQLRQERHRKFREEEQLLQER 1429
Score = 32.3 bits (72), Expect = 2.3
Identities = 40/204 (19%), Positives = 88/204 (42%), Gaps = 7/204 (3%)
Query: 121 RKHSAETRERIKRRTSEALREPKVRKKMAEHPRFHSDKIKE-KISYSLRRVWQERLKSKR 179
R+H RE+ +RR RE + + R H ++ +E +++ + +ER+KS+
Sbjct: 661 RRHEQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 720
Query: 180 FREQIFLSWEQCIANA---AKKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMA 236
+ Q L E + + G+ E + K + + ELQ Q EE+ +
Sbjct: 721 PKWQWQLESEADARQSKVLLEAPQAGRAEAPQEQEEKRRRESELQ--WQEEERAHRQQQE 778
Query: 237 IARAEKFIQSW-SECLAKEAKKGGSGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKER 295
+ F W +E ++ ++ S L +++ E + R E+ + ++R
Sbjct: 779 EEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQR 838
Query: 296 ARTKAEKEARIKAIKKVMLNQKKK 319
R + E+E ++ +++ Q+++
Sbjct: 839 GRQRREREKELQFLEEEEQLQRRE 862
Score = 32.3 bits (72), Expect = 2.3
Identities = 49/245 (20%), Positives = 103/245 (42%), Gaps = 20/245 (8%)
Query: 89 EIESLSRKAVKERMRRFKIGLANKGRVPWNK--------GRKHSAETRERIKRRTSEALR 140
E + +R+ +K R+ +++ L ++ +K GR + + +E +RR SE
Sbjct: 707 EEQEQARERIKSRIPKWQWQLESEADARQSKVLLEAPQAGRAEAPQEQEEKRRRESEL-- 764
Query: 141 EPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGG 200
+ E R H + +E+ WQ KS+R R++ LS + ++
Sbjct: 765 ------QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR--LSARPPLREQRERQL 816
Query: 201 CGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGS 260
+E + +E+ + Q+ Q E+EKE L + E+ + +E + G
Sbjct: 817 RAEERQQREQRFLPEEEEKEQRGRQRREREKE-LQFLEEEEQLQRRERAQQLQEEEDGLQ 875
Query: 261 GEKELDWDSYEKIQEEMFLLNQIR-RTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKK 319
++E + Q+ + L + R R AK + + KE ++ ++ L ++++
Sbjct: 876 EDQERRRQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREER 935
Query: 320 DLRER 324
+ R R
Sbjct: 936 EKRRR 940
>IF2P_HUMAN (O60841) Eukaryotic translation initiation factor 5B
(eIF-5B) (Translation initiation factor IF-2)
Length = 1220
Score = 52.8 bits (125), Expect = 2e-06
Identities = 73/331 (22%), Positives = 134/331 (40%), Gaps = 50/331 (15%)
Query: 59 DDSDNQSETSVDSSDYLNGGDGVVGLSDSLEIESLSRKAVKERMRRFKIGLANKGRVPWN 118
DD+D++ DS V S S + + ++ K + G A K W+
Sbjct: 109 DDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAK------GKAQKSNKKWD 162
Query: 119 KGRKHSAETRERIKRRT------------SEALREPKVRKKMAEH---PRFHSDKIKEKI 163
G + + ++IK R+ E L+ K +KK ++ P S +
Sbjct: 163 -GSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDA 221
Query: 164 SYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQL 223
S+ ++ V Q++ + K RE+ E+ K+ +EEL+ ++ K++ ++
Sbjct: 222 SFKIKTVAQKKAEKKE-RERKKRDEEKAKLRKLKE----KEELETGKKDQSKQKESQRKF 276
Query: 224 LQAEEKEK------------EKLMAIARAEKFIQSWSECLAKEAKKGGSGEKELDWD--- 268
+ K K EK AE + + K+ KKG EKE +
Sbjct: 277 EEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGP 336
Query: 269 ---SYEKIQEEMFLLN-----QIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKD 320
+ + +QE + L Q R E+ K E K ++E R++ K+ QK+K+
Sbjct: 337 SKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKE 396
Query: 321 LRERIKGRGNIKSQLCKNANEDGEAALEITQ 351
+ER+K G + ++ + A EA L++ Q
Sbjct: 397 RKERLKKEGKLLTKSQREARARAEATLKLLQ 427
>MST2_DROHY (Q08696) Axoneme-associated protein mst101(2)
Length = 1391
Score = 51.6 bits (122), Expect = 4e-06
Identities = 82/347 (23%), Positives = 146/347 (41%), Gaps = 39/347 (11%)
Query: 89 EIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIK-RRTSEALREPKVRKK 147
E E+ RK +E ++ K K + K E ER K ++ +++ +++KK
Sbjct: 454 EKEAAERKKCEELAKKIKKAAEKK---KCEETAKKGKEVAERKKCEELAKKIKKAEIKKK 510
Query: 148 MAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEELD 207
+ + KEK + ++ + K K E+ ++C A K+ +++
Sbjct: 511 CKKLAK------KEKETAEKKKCEKAAKKRKEAAEK-----KKCEKAAKKRKEAAEKKKC 559
Query: 208 WDSYNKIKEQLELQQLLQA-----EEKEKEKLMAIARAEKFIQSWSEC--LAKEAKKGG- 259
S K KE E ++ +A E EK+K A+ EK + +C LAK+ KK
Sbjct: 560 EKSAKKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAE 619
Query: 260 ------SGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTK---AEKEARIKAIK 310
+ +KE + EK E L +I++ EK K K+ A+ + AEK+ KA K
Sbjct: 620 KKKCKEAAKKEKEAAEREKCGE---LAKKIKKAAEKKKCKKLAKKEKETAEKKKCEKAAK 676
Query: 311 K-VMLNQKKKDLRERIKGRGNIKSQLCKNANEDGEAALEITQQFKLDTKLTKINISKNIN 369
K +KKK K + + + C+ A + + A E + +L K+ K K
Sbjct: 677 KRKEAAEKKKCAEAAKKEKEAAEKKKCEEAAKKEKEAAERKKCEELAKKIKKAAEKKKCK 736
Query: 370 SEVAREGGFSNSIYPTYNKLDLEVIKREKLRKEASFADRIQAARLKK 416
++ + NK + +K +K +E + + +AA KK
Sbjct: 737 KLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELA---KKKAAEKKK 780
Score = 49.7 bits (117), Expect = 1e-05
Identities = 71/279 (25%), Positives = 118/279 (41%), Gaps = 22/279 (7%)
Query: 89 EIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETR--ERIKRRTSEALREPKVRK 146
E E+ +K ++ ++ K K K RK +AE + E+ ++ EA + K K
Sbjct: 518 EKETAEKKKCEKAAKKRKEAAEKKKCEKAAKKRKEAAEKKKCEKSAKKRKEAAEKKKCEK 577
Query: 147 KMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQ--CIANAAKKGGCGQE 204
E K E+ + + V ER K + ++I + E+ C A K+ +
Sbjct: 578 AAKERKEAAEKKKCEEAAKKEKEV-AERKKCEELAKKIKKAAEKKKCKEAAKKEKEAAER 636
Query: 205 ELDWDSYNKIKEQLELQQLLQAEEKEKE-----KLMAIARAEKFIQSWSECLAKEAKKGG 259
E + KIK+ E ++ + +KEKE K A+ K +C K+
Sbjct: 637 EKCGELAKKIKKAAEKKKCKKLAKKEKETAEKKKCEKAAKKRKEAAEKKKCAEAAKKEKE 696
Query: 260 SGEKELDWDSYEKIQEEMF------LLNQIRRTTEKAKAKERARTK--AEKEARIKAIKK 311
+ EK+ ++ +K +E L +I++ EK K K+ A+ K EK K KK
Sbjct: 697 AAEKKKCEEAAKKEKEAAERKKCEELAKKIKKAAEKKKCKKLAKKKKAGEKNKLKKGNKK 756
Query: 312 --VMLNQKKKDLRERIKGRGNIKSQLCKNANEDGEAALE 348
L +KKK RE K + K + CK A + + A E
Sbjct: 757 GKKALKEKKK-CRELAKKKAAEKKK-CKEAAKKEKEAAE 793
Score = 49.7 bits (117), Expect = 1e-05
Identities = 64/247 (25%), Positives = 106/247 (42%), Gaps = 22/247 (8%)
Query: 112 KGRVPWNKGRKHSAETRERIKRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVW 171
KG+ N +K RE +K + E E K+R + E + +K +K L R
Sbjct: 286 KGKKKKNDEKKEKELEREILKEQAEE---EAKIRGVVKEVKKKCKEKALKKKCKDLGRKM 342
Query: 172 QERLKSKRFREQIFLSWEQ-----CIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQA 226
+E + K+ E+ C A KK +++ ++ NK K+ E ++ +A
Sbjct: 343 KEEAEKKKCAALAKKQKEEDEKKACKELAKKKKEADEKKKCEEAANKEKKAAEKKKCEKA 402
Query: 227 -----EEKEKEKLMAIARAEKFIQSWSEC--LAKEAKKGGSGEKELDWDSYEKIQEEMFL 279
E EK+K A+ EK +C LAK KK +K + EK E
Sbjct: 403 AKERKEAAEKKKCEEAAKKEKEAAERKKCEELAKNIKKAAEKKKCKEAAKKEKEAAER-- 460
Query: 280 LNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDLRERIKGRGNIKSQLCKNA 339
++ E AK ++A K + E K K+V +K ++L ++IK + IK + K A
Sbjct: 461 ----KKCEELAKKIKKAAEKKKCEETAKKGKEVAERKKCEELAKKIK-KAEIKKKCKKLA 515
Query: 340 NEDGEAA 346
++ E A
Sbjct: 516 KKEKETA 522
Score = 48.5 bits (114), Expect = 3e-05
Identities = 65/269 (24%), Positives = 114/269 (42%), Gaps = 27/269 (10%)
Query: 91 ESLSRKAVKERMRRFKIGLANK---GRVPWNKGRKHSAETRERIKRRTSEALR---EPKV 144
++ +K K+ ++ K G NK G K K + RE K++ +E + K
Sbjct: 728 KAAEKKKCKKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKKAAEKKKCKEAAKK 787
Query: 145 RKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQE 204
K+ AE + K K ++ + K K E+ ++C A K+ ++
Sbjct: 788 EKEAAEKKKCEKTAKKRKEEAEKKKCEKTAKKRKEAAEK-----KKCEKAAKKRKEEAEK 842
Query: 205 ELDWDSYNKIKEQLELQQLLQAEEK-----EKEKLMAIARAEKFIQSWSECLAKEAKKGG 259
+ + K KE E ++ +A +K EK+K A+ K +C A+ AKK
Sbjct: 843 KKCEKTAKKRKETAEKKKCEKAAKKRKQAAEKKKCEKAAKKRKEAAEKKKC-AEAAKK-- 899
Query: 260 SGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKK 319
EKEL + +K EE + + E+ K +E A+ K +K A K KK+ +KK
Sbjct: 900 --EKEL---AEKKKCEEA--AKKEKEVAERKKCEELAK-KIKKAAEKKKCKKLAKKEKKA 951
Query: 320 DLRERIKGRGNIKSQLCKNANEDGEAALE 348
+ ++K + + CK + + A E
Sbjct: 952 GEKNKLKKKAGKGKKKCKKLGKKSKRAAE 980
Score = 48.5 bits (114), Expect = 3e-05
Identities = 79/346 (22%), Positives = 149/346 (42%), Gaps = 37/346 (10%)
Query: 91 ESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVRKKMAE 150
E+ +K +ER ++ K K K K +AE ++ +R ++ L+E +K+ E
Sbjct: 1025 EAAEQKQCEERAKKLKEAAEKKQCEERAKKLKEAAEQKQCEER--AKKLKEAAEKKQCEE 1082
Query: 151 HPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWE-----QCIANAAKKGGCGQEE 205
+ + ++K + +E + K+ E+ E +C A ++ +++
Sbjct: 1083 RAKKEKEAAEKKQCEERAKKLKEAAEKKQCEERAKKEKEAAEKKRCEEAAKREKEAAEKK 1142
Query: 206 LDWDSYNKIKEQLELQQLLQAEEKEKE-----KLMAIARAEKFIQSWSEC--LAKEAKKG 258
++ K KE E Q+ +A +KEKE K A+ EK +C LAK+ ++
Sbjct: 1143 KCAEAAKKEKEATEKQKCAEAAKKEKEAAEKKKCAEAAKREKEAAQKKKCADLAKKEQEP 1202
Query: 259 GSGEK-----ELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTK---AEKEARIKAIK 310
+K + + ++ EK Q+ + + EK K E A+ + AEK+ +A K
Sbjct: 1203 AEMKKCEEAAKKEKEAAEK-QKCAKAAKKEKEAAEKKKCAEAAKKEQEAAEKKKCAEAAK 1261
Query: 311 KVMLNQKKKDLRERIKGRGNIKSQLCKNANEDGEAALEITQQFKLDTKLTKINISKNINS 370
K +KK+ E+ + +K Q K EAAL ++ + K K+ K
Sbjct: 1262 KEKEAEKKRKC-EKAEKAAALKRQCAKLVIRAKEAALR--KKCAIIAKKAKMAAEKKECE 1318
Query: 371 EVAREGGFSNSIYPTYNKLDLEVIKREKLRKEASFADRIQAARLKK 416
++A++ K +E K KL K+ A++ + A+L K
Sbjct: 1319 KLAKKA-----------KEAIEWKKCAKLAKKKREAEKKKCAKLAK 1353
Score = 45.8 bits (107), Expect = 2e-04
Identities = 67/272 (24%), Positives = 113/272 (40%), Gaps = 21/272 (7%)
Query: 89 EIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVRKKM 148
E + RK E+ + K K K + + + +E +R+ E L K KK
Sbjct: 560 EKSAKKRKEAAEKKKCEKAAKERKEAAEKKKCEEAAKKEKEVAERKKCEELA--KKIKKA 617
Query: 149 AEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEELDW 208
AE + KEK + + + K K+ E+ ++C A K+ +++
Sbjct: 618 AEKKKCKEAAKKEKEAAEREKCGELAKKIKKAAEK-----KKCKKLAKKEKETAEKKKCE 672
Query: 209 DSYNKIKEQLELQQLLQAEEKEKE-----KLMAIARAEKFIQSWSEC--LAKEAKKGGSG 261
+ K KE E ++ +A +KEKE K A+ EK +C LAK+ KK
Sbjct: 673 KAAKKRKEAAEKKKCAEAAKKEKEAAEKKKCEEAAKKEKEAAERKKCEELAKKIKKAAEK 732
Query: 262 EKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIK------AIKKVMLN 315
+K +K E+ L ++ + K K++ R A+K+A K A K+
Sbjct: 733 KKCKKLAKKKKAGEKNKLKKGNKKGKKALKEKKKCRELAKKKAAEKKKCKEAAKKEKEAA 792
Query: 316 QKKKDLRERIKGRGNIKSQLC-KNANEDGEAA 346
+KKK + K + + + C K A + EAA
Sbjct: 793 EKKKCEKTAKKRKEEAEKKKCEKTAKKRKEAA 824
Score = 41.2 bits (95), Expect = 0.005
Identities = 61/230 (26%), Positives = 103/230 (44%), Gaps = 32/230 (13%)
Query: 121 RKHSAETRERIKRRTSEALREPKVRKKMA--EHPRFHSDKIKEKISYSLRRVWQERLKSK 178
RK E ++IK+ E K KK+A E +K+K+K ++ + KSK
Sbjct: 922 RKKCEELAKKIKKAA-----EKKKCKKLAKKEKKAGEKNKLKKKAGKGKKKCKKLGKKSK 976
Query: 179 RFREQIFLSWEQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIA 238
R E+ ++C A K+ ++ + K KE E +Q + +K KE A
Sbjct: 977 RAAEK-----KKCAEAAKKEKEAATKKKCEERAKKQKEAAEKKQCEERAKKLKE-----A 1026
Query: 239 RAEKFIQSWSECLAKEAKKGGSGE--KELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERA 296
+K + ++ L + A+K E K+L + +K EE +++ EK + +ERA
Sbjct: 1027 AEQKQCEERAKKLKEAAEKKQCEERAKKLKEAAEQKQCEER--AKKLKEAAEKKQCEERA 1084
Query: 297 RTKAEKEARIKAIKKVMLNQKKKDLRERIKGRGNIKSQLCKNANEDGEAA 346
K EKEA +K ++ K L+E + K Q + A ++ EAA
Sbjct: 1085 --KKEKEAA----EKKQCEERAKKLKEAAE-----KKQCEERAKKEKEAA 1123
Score = 40.8 bits (94), Expect = 0.007
Identities = 58/257 (22%), Positives = 108/257 (41%), Gaps = 22/257 (8%)
Query: 92 SLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVRKKMAEH 151
+L++K +E ++ LA K + K + A +E+ + + K RK+ AE
Sbjct: 353 ALAKKQKEEDEKKACKELAKKKKEADEKKKCEEAANKEKKAAEKKKCEKAAKERKEAAEK 412
Query: 152 PRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEELDWDSY 211
+ KEK + ++ + K+ E+ ++C A K+ + + +
Sbjct: 413 KKCEEAAKKEKEAAERKKCEELAKNIKKAAEK-----KKCKEAAKKEKEAAERKKCEELA 467
Query: 212 NKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKELDWDSYE 271
KIK+ E ++ + +K KE +A +K E LAK+ KK +K E
Sbjct: 468 KKIKKAAEKKKCEETAKKGKE----VAERKK-----CEELAKKIKKAEIKKKCKKLAKKE 518
Query: 272 KIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDLRERIKGRGNI 331
K E ++ EKA AK+R +K+ A K+ +KKK + K +
Sbjct: 519 KETAE-------KKKCEKA-AKKRKEAAEKKKCEKAAKKRKEAAEKKKCEKSAKKRKEAA 570
Query: 332 KSQLCKNANEDGEAALE 348
+ + C+ A ++ + A E
Sbjct: 571 EKKKCEKAAKERKEAAE 587
Score = 38.9 bits (89), Expect = 0.025
Identities = 69/330 (20%), Positives = 128/330 (37%), Gaps = 22/330 (6%)
Query: 91 ESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETR--ERIKRRTSEALREPKVRKKM 148
E+ +K E ++ K K K K +AE + E + ++ +A + K +K
Sbjct: 680 EAAEKKKCAEAAKKEKEAAEKKKCEEAAKKEKEAAERKKCEELAKKIKKAAEKKKCKKLA 739
Query: 149 AEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEELDW 208
+ +K+K K + ++ +E+ K + ++ ++C AAKK E
Sbjct: 740 KKKKAGEKNKLK-KGNKKGKKALKEKKKCRELAKKKAAEKKKC-KEAAKKEKEAAE---- 793
Query: 209 DSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKELDWD 268
K++ E + EE EK+K A+ K +C K+ EK+
Sbjct: 794 ------KKKCEKTAKKRKEEAEKKKCEKTAKKRKEAAEKKKCEKAAKKRKEEAEKKKCEK 847
Query: 269 SYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDLRERIKGR 328
+ +K +E ++ EKA AK+R + +K+ A K+ +KKK K +
Sbjct: 848 TAKKRKE-----TAEKKKCEKA-AKKRKQAAEKKKCEKAAKKRKEAAEKKKCAEAAKKEK 901
Query: 329 GNIKSQLCKNANEDGEAALEITQQFKLDTKLTKINISKNINSEVARE--GGFSNSIYPTY 386
+ + C+ A + + E + +L K+ K K +E G N +
Sbjct: 902 ELAEKKKCEEAAKKEKEVAERKKCEELAKKIKKAAEKKKCKKLAKKEKKAGEKNKLKKKA 961
Query: 387 NKLDLEVIKREKLRKEASFADRIQAARLKK 416
K + K K K A+ + A K+
Sbjct: 962 GKGKKKCKKLGKKSKRAAEKKKCAEAAKKE 991
Score = 34.3 bits (77), Expect = 0.61
Identities = 55/279 (19%), Positives = 120/279 (42%), Gaps = 31/279 (11%)
Query: 108 GLANKGRVPW-NKGRKHSAETRERIKRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYS 166
GL++ R+ + N G+ S + +I+ + + K ++K E + + K +
Sbjct: 34 GLSSFQRLSFSNTGKNESTDDSNQIRCDADKTAADKK-KQKQKEEEQAKIREYKRECLKV 92
Query: 167 LRRVWQERLKSKRFREQIFLS-WEQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQ 225
+RV E ++ +++I + +C+ + KK + KI + L
Sbjct: 93 QKRVLAEEIRCSGEKDRILIQGMMKCLTDGMKK-----------ACTKIAKAK-----LI 136
Query: 226 AEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKELDWDSYEKIQEEMFLLNQIRR 285
A+++ + A+++ +K + L K+ ++ S EKE + +S + ++ + ++
Sbjct: 137 ADKELAVQCAALSKKDKV-----KALLKKCEREKSKEKECNQNSPAEGDKD-----RTKK 186
Query: 286 TTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDLRERIKGRGNIKSQLCKNANEDGEA 345
K K+ + ++ KE R K KK++ N+ + L IK + +N ED
Sbjct: 187 GKTKGKSGGGNKKRSTKENRAKKGKKLVKNRFTQKLEHCIKSEWADVCECRQNFTEDERK 246
Query: 346 ALEITQQFKLDTKLTKINISKNINSEVAREGGFSNSIYP 384
L + + + TK+ I K + +E+ G+ S P
Sbjct: 247 RLAASYKC-MGTKIKSI-CRKRVIAEMCEAAGYVKSSEP 283
>M21_STRPY (P50468) M protein, serotype 2.1 precursor
Length = 407
Score = 50.8 bits (120), Expect = 6e-06
Identities = 68/266 (25%), Positives = 120/266 (44%), Gaps = 26/266 (9%)
Query: 90 IESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVRKKMA 149
+E L R++ +E +R++ L + ++ + K +E + RR EA R K + A
Sbjct: 128 LEELERQSQREVEKRYQEQLQKQQQL---EKEKQISEASRKSLRRDLEASRAAK-KDLEA 183
Query: 150 EHPRFHSDK-IKEKISYSLRRVWQERLKSKRFREQIF--LSWEQCIANAAKKGGCGQEEL 206
EH + +K I E SLRR + +K+ E L E+ I+ A+++G
Sbjct: 184 EHQKLKEEKQISEASRKSLRRDLEASRAAKKDLEAEHQKLKEEKQISEASRQG----LSR 239
Query: 207 DWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKELD 266
D ++ K+ LE + EEK+ I+ A + S ++EAKK + E D
Sbjct: 240 DLEASRAAKKDLEAEHQKLKEEKQ------ISEASRQGLSRDLEASREAKK----KVEAD 289
Query: 267 WDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDLRERIK 326
+ + LN+ +K KE+A +A+ EA KA+K+ + Q ++ ++K
Sbjct: 290 LAEANSKLQALEKLNKELEEGKKLSEKEKAELQAKLEAEAKALKEQLAKQAEE--LAKLK 347
Query: 327 GRGNIKSQLCKNANEDGEAALEITQQ 352
G +++ AN A +TQQ
Sbjct: 348 GNQTPNAKVAPQANRSRSA---MTQQ 370
>INCE_CHICK (P53352) Inner centromere protein
Length = 877
Score = 50.8 bits (120), Expect = 6e-06
Identities = 67/291 (23%), Positives = 121/291 (41%), Gaps = 41/291 (14%)
Query: 112 KGRVPWNKGRKHSAETRERIK----RRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSL 167
K + +N +H + +ER K R+ EA E ++K+ E + ++ K + L
Sbjct: 489 KSFIKYNTPLQHDPKEKERQKLQALRKKEEA--EQLRKQKVEEEKKRRQEEAKLRREERL 546
Query: 168 RRVWQERLKSKRFREQIFLSWEQCIA----------------NAAKKGGCGQEELDWDSY 211
R+V Q R ++++ E+ EQ +A KK ++ + ++
Sbjct: 547 RKVLQARERAEQLEEERKRRIEQKLALFDEKTEKAREERLAEEKIKKRAAAKKMEEAEAR 606
Query: 212 NKIKEQLELQQLLQAEEKE--------KEKLMAIARAEKFIQSWSECLAKEAKKGGSGEK 263
+ E+ Q+ LQ EE+E K+K RA K + +E + E+
Sbjct: 607 RRQDEEARKQKALQQEEEERRHKELMQKKKEEEQERARKIAEQRQAEQEREKQLAAEREQ 666
Query: 264 ELDWDSYEKIQEEMFLLNQIRRTTEKA--------KAKERARTKAEKEARIKAIKKVM-- 313
E + K +EE + R EKA AKE+ + + EK+ + + + M
Sbjct: 667 ERKKEQERKKEEERIQAEKQREQQEKAARLQKEVLAAKEQLQKEMEKKEKEEQLLAEMKR 726
Query: 314 LNQKKKDLRERIKGRGNIKSQLCKN-ANEDGEAALEITQQFKLDTKLTKIN 363
Q++K L E K + ++Q +N N + ++T Q+ D K KIN
Sbjct: 727 QEQEQKKLPEEQKAKDVAQTQHLENKENSPACNSYQMTPQYHKDPKPPKIN 777
Score = 39.3 bits (90), Expect = 0.019
Identities = 40/169 (23%), Positives = 81/169 (47%), Gaps = 19/169 (11%)
Query: 91 ESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVR----- 145
E L+ + +K+R K+ A R + RK A +E +RR E +++ K
Sbjct: 584 ERLAEEKIKKRAAAKKMEEAEARRRQDEEARKQKALQQEEEERRHKELMQKKKEEEQERA 643
Query: 146 KKMAEHPRFHSDKIK--------EKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAK 197
+K+AE + ++ K E+ R+ +ER+++++ REQ ++ A K
Sbjct: 644 RKIAEQRQAEQEREKQLAAEREQERKKEQERKKEEERIQAEKQREQ-----QEKAARLQK 698
Query: 198 KGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQS 246
+ +E+L + K KE+ +L ++ +E+E++KL +A+ Q+
Sbjct: 699 EVLAAKEQLQKEMEKKEKEE-QLLAEMKRQEQEQKKLPEEQKAKDVAQT 746
>TRHY_SHEEP (P22793) Trichohyalin
Length = 1549
Score = 48.9 bits (115), Expect = 2e-05
Identities = 57/265 (21%), Positives = 123/265 (45%), Gaps = 29/265 (10%)
Query: 91 ESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETR----ERIKRRTSEALREPKVRK 146
E R+ +ER K+ L + ++ + K E E+++ + E L+ + K
Sbjct: 496 EREKRRQERERQYLEKVELQEEEQLQREEREKRRQERERQYLEKVELQEEEQLQRQEREK 555
Query: 147 KMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEEL 206
+ E + + +K++ + L+R QER K ++ RE+ +L + + + +E+
Sbjct: 556 RRQEREKQYLEKVELQEEEQLQR--QERQKRRQEREKQYLEKVE-LQEEEQLQRQEREKR 612
Query: 207 DWDSYNKIKEQLELQQLLQAEEKEKEKLMA----------IARAEKFIQSWSECLAKEAK 256
+ + E++ELQ+ Q + +E+EK + R E+ +Q + L +E +
Sbjct: 613 RQERERQYLEKVELQEEEQVQRQEREKRRQERERQYLEKELQRQEERLQEEEQLLREERE 672
Query: 257 KGGSGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEK------EARIKAIK 310
K E+E + ++QEE Q++R + + +ER R EK E R++ +
Sbjct: 673 KRRQ-ERERQYLEKVELQEE----EQLQREEREKRRQERERQYLEKEELQRQEERLQR-E 726
Query: 311 KVMLNQKKKDLRERIKGRGNIKSQL 335
K L ++ ++ R +++ R ++ +L
Sbjct: 727 KEQLQREDREKRRQVRERKYLEEEL 751
Score = 46.6 bits (109), Expect = 1e-04
Identities = 50/246 (20%), Positives = 112/246 (45%), Gaps = 19/246 (7%)
Query: 91 ESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETR----ERIKRRTSEALREPKVRK 146
E R+ +E+ K+ L + ++ + K E E+++ + E L+ + K
Sbjct: 468 EREKRRQEREKQYLEKVELREEEQLQRQEREKRRQERERQYLEKVELQEEEQLQREEREK 527
Query: 147 KMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEEL 206
+ E R + +K++ + L+R QER K ++ RE+ +L + +E+L
Sbjct: 528 RRQERERQYLEKVELQEEEQLQR--QEREKRRQEREKQYLEKVELQE---------EEQL 576
Query: 207 DWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKELD 266
K +++ E Q L + E +E+E+L R ++ + + L K + + +
Sbjct: 577 QRQERQKRRQEREKQYLEKVELQEEEQLQRQEREKRRQERERQYLEKVELQEEEQVQRQE 636
Query: 267 WDSYEKIQEEMFLLNQIRRTTEKAKAKERA----RTKAEKEARIKAIKKVMLNQKKKDLR 322
+ + +E +L +++R E+ + +E+ R K +E + ++KV L ++++ R
Sbjct: 637 REKRRQERERQYLEKELQRQEERLQEEEQLLREEREKRRQERERQYLEKVELQEEEQLQR 696
Query: 323 ERIKGR 328
E + R
Sbjct: 697 EEREKR 702
Score = 42.7 bits (99), Expect = 0.002
Identities = 50/244 (20%), Positives = 120/244 (48%), Gaps = 19/244 (7%)
Query: 91 ESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETR----ERIKRRTSEALREPKVRK 146
E R+ +E+ K+ L + ++ + +K E E+++ + E L+ + K
Sbjct: 552 EREKRRQEREKQYLEKVELQEEEQLQRQERQKRRQEREKQYLEKVELQEEEQLQRQEREK 611
Query: 147 KMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEEL 206
+ E R + +K++ + ++R QER K ++ RE+ +L E ++ +E+L
Sbjct: 612 RRQERERQYLEKVELQEEEQVQR--QEREKRRQERERQYLEKE---LQRQEERLQEEEQL 666
Query: 207 DWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKE----AKKGGSGE 262
+ K +++ E Q L + E +E+E+L R ++ + + L KE ++ E
Sbjct: 667 LREEREKRRQERERQYLEKVELQEEEQLQREEREKRRQERERQYLEKEELQRQEERLQRE 726
Query: 263 KEL----DWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKK 318
KE D + +++E +L ++++ ++ + +E+ + ++E R + ++KV L +++
Sbjct: 727 KEQLQREDREKRRQVRERKYLEEELQQEEDRLQ-REKQLLREDREKR-QYLEKVELQREE 784
Query: 319 KDLR 322
+ L+
Sbjct: 785 EQLQ 788
Score = 41.2 bits (95), Expect = 0.005
Identities = 57/250 (22%), Positives = 108/250 (42%), Gaps = 33/250 (13%)
Query: 129 ERIKRRTSEALR----EPKVRKKMAEHPRFHSDK-IKEKISYSLRRVWQERLKSKRFREQ 183
E++ R E LR EP++R+K +FH ++ + ++ LRR QER + R Q
Sbjct: 1098 EQLLREREEQLRLQEGEPQLRQKRDR--KFHEEEQLLQEREEQLRR--QERDRKFREEAQ 1153
Query: 184 IFLSWEQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKF 243
I E+ + + D + +EQL LQ+ + +E+E + R KF
Sbjct: 1154 ILKEREEQLRRQER-----------DRKFREEEQL-LQEREELRRQEREPQLRQERDRKF 1201
Query: 244 IQSWSECLAKEAKKGGSGEKELDWDSYEKIQEEMFLL----NQIRRTTEKAKAKERARTK 299
+ +E + E +L + K EE LL Q+RR K +E A+
Sbjct: 1202 REEEQLLQEREKLRRQEREPQLRQERDRKFHEEEQLLQEREEQLRRQERDRKFREEAQLL 1261
Query: 300 AEKEARIKAIKK--------VMLNQKKKDLRERIKGRGNIKSQLCKNANEDGEAALEITQ 351
E+E +++ ++ +L ++++ LR + + R + + E+ E +
Sbjct: 1262 QEREEQLRRQERDRKFREEEQLLQEREEQLRRQERDRKFREEEQLLQEREEQLRRQERDR 1321
Query: 352 QFKLDTKLTK 361
+F+ + +L K
Sbjct: 1322 KFREEEQLLK 1331
Score = 40.4 bits (93), Expect = 0.009
Identities = 49/199 (24%), Positives = 94/199 (46%), Gaps = 18/199 (9%)
Query: 126 ETRERIKRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIF 185
+ R+R R + L+E + + + E R K EK + LR +++L+ + E +F
Sbjct: 1317 QERDRKFREEEQLLKESEEQLRRQERDR----KFHEK-EHLLREREEQQLRRQEL-EGVF 1370
Query: 186 LSWEQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQ 245
S E+ + A QEE + ++ LE +Q LQ E+E+EK + KF++
Sbjct: 1371 -SQEEQLRRAE------QEEEQRRQRQRDRKFLEEEQSLQ-REREEEKRRVQEQDRKFLE 1422
Query: 246 SWSECLAKEAKKGGSGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEAR 305
E L +E ++ ++LD + EE F + RR E+ +E R + E+E +
Sbjct: 1423 Q-EEQLHREEQEELRRRQQLD---QQYRAEEQFAREEKRRRQEQELRQEEQRRRQERERK 1478
Query: 306 IKAIKKVMLNQKKKDLRER 324
+ +++ Q+++ R +
Sbjct: 1479 FREEEQLRRQQQEEQKRRQ 1497
Score = 39.3 bits (90), Expect = 0.019
Identities = 66/341 (19%), Positives = 142/341 (41%), Gaps = 25/341 (7%)
Query: 89 EIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKV---- 144
+++ R+ +ER R + L + R+ + + E +R ++ L E ++
Sbjct: 786 QLQREKRRQERERQYREEELLREEERLHRKEQQLQREECEKRRRQELERQLEEEELQRLD 845
Query: 145 RKKMAEHPRFHSDKIKEKISYSLRRVWQER---LKSKRFREQIFLSWEQCIANAAKKGGC 201
RK+ H ++++ YS R +E+ L RE F + + + ++
Sbjct: 846 RKRQFRDDDQHQNEVRNSRVYSKHRENKEKSRQLDDSWVRESQFQQDLRPLQDEQEEKR- 904
Query: 202 GQEELDWDSYNKIKEQLELQQLLQAE-EKEKEKLMAIARAEKFIQSWSECLAKEAKKGGS 260
+ E +W S K Q +QLL+ E +KE E+ R KF + ++ KG
Sbjct: 905 -EREQEWRSRQKRDSQFPAEQLLEREQQKETER-----RDRKFREE------EQLLKGQR 952
Query: 261 GEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERA-RTKAEKEARIKAIK--KVMLNQK 317
EK + K +EE L ++ R + + ++R R + ++ R + + + +L ++
Sbjct: 953 EEKIRYLEEDRKFREEEQQLRRLEREQQLRQERDRKFREELSRQERDRKFREEEQLLQER 1012
Query: 318 KKDLRERIKGRGNIKSQLCKNANEDGEAALEITQQFKLDTKLTKINISKNINSEVARE-G 376
++ LR + + R + + E+ E ++F+ + +L + + E R+
Sbjct: 1013 EEQLRRQERDRKFREEEQLLQEREEQLRRQERDRKFREEEQLLQEREEQLRRQERDRKFR 1072
Query: 377 GFSNSIYPTYNKLDLEVIKREKLRKEASFADRIQAARLKKG 417
+ + L + K R+E +R + RL++G
Sbjct: 1073 EEEQQLRLLEREQQLRQERNRKFREEQLLREREEQLRLQEG 1113
Score = 38.9 bits (89), Expect = 0.025
Identities = 43/209 (20%), Positives = 92/209 (43%), Gaps = 30/209 (14%)
Query: 129 ERIKRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSW 188
E+++R RE + R+ + + +E++ R + + + K++ E++ L W
Sbjct: 401 EKLQREKRRQERERQYREVELQREEERLQREEEQLQREEREKRRRQEREKQYLEKVEL-W 459
Query: 189 EQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIAR--------- 239
E+ E+L + K +++ E Q L + E +E+E+L R
Sbjct: 460 EE-------------EQLQREEREKRRQEREKQYLEKVELREEEQLQRQEREKRRQERER 506
Query: 240 --AEKFIQSWSECLAKEAKKGGSGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERAR 297
EK E L +E ++ E+E + ++QEE Q++R + + +ER +
Sbjct: 507 QYLEKVELQEEEQLQREEREKRRQERERQYLEKVELQEE----EQLQRQEREKRRQEREK 562
Query: 298 TKAEKEARIKAIKKVMLNQKKKDLRERIK 326
EK ++ +++ +++K +ER K
Sbjct: 563 QYLEK-VELQEEEQLQRQERQKRRQEREK 590
>SNXN_HUMAN (Q96L93) Kinesin-like motor protein C20orf23 (Sorting
nexin 23)
Length = 1317
Score = 48.1 bits (113), Expect = 4e-05
Identities = 67/290 (23%), Positives = 133/290 (45%), Gaps = 30/290 (10%)
Query: 84 LSDSLEIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPK 143
L + +E + S KA ERM++ + + + RK E +KRR+ E K
Sbjct: 615 LIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQE----ESLKRRSFHI--ENK 668
Query: 144 VRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQ 203
++ +AE +F ++++E+ L++ QE R +E++ E A+K Q
Sbjct: 669 LKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQ 728
Query: 204 EELDWDSYNKIKEQ----LELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGG 259
E D K K++ LEL++ + EE+EKE++M +A E+ ++ E + + ++G
Sbjct: 729 E---LDQLQKEKDEQYAKLELEKK-RLEEQEKEQVMLVAHLEEQLREKQE-MIQLLRRGE 783
Query: 260 SGEKELDWDSYEKIQEEMFLLNQIRR-TTEKAKAKERARTKAEKEARIKAIKKVMLN--- 315
E + E I+E + + + R E + E+A+ + + R + +K V L
Sbjct: 784 VQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDL 843
Query: 316 -----------QKKKDLRERIKGRGNIKSQLCKNANEDGEAALEITQQFK 354
Q+++++ E +K + +S+L + +E E+ Q F+
Sbjct: 844 VQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFE 893
>PPG1_PIG (Q865B6) Peroxisome proliferator activated receptor gamma
coactivator 1 alpha (PPAR gamma coactivator-1 alpha)
(PPARGC-1 alpha) (PGC-1 alpha)
Length = 796
Score = 47.8 bits (112), Expect = 5e-05
Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 267 WDSYEKIQEEMFLLNQIRRTTEK-----AKAKERARTKAEKEARIKAIKKVMLNQKKKDL 321
+DSYE+ Q E + RR EK AK +ER R KA +E R+ + K+ + + +L
Sbjct: 632 YDSYEEYQHERLKREEYRREYEKRESERAKQRERQRQKAIEERRVIYVGKIRPDTTRTEL 691
Query: 322 RERIKGRGNIKSQLCKNANEDGEAALEITQQFKLD 356
R+R + G I+ + N +DG++ IT ++ D
Sbjct: 692 RDRFEVFGEIE-ECTVNLRDDGDSYGFITYRYTCD 725
>PPG1_HUMAN (Q9UBK2) Peroxisome proliferator activated receptor
gamma coactivator 1 alpha (PPAR gamma coactivator-1
alpha) (PPARGC-1 alpha) (PGC-1 alpha) (Ligand effect
modulator-6)
Length = 798
Score = 47.8 bits (112), Expect = 5e-05
Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 267 WDSYEKIQEEMFLLNQIRRTTEK-----AKAKERARTKAEKEARIKAIKKVMLNQKKKDL 321
+DSYE+ Q E + RR EK AK +ER R KA +E R+ + K+ + + +L
Sbjct: 634 YDSYEEYQHERLKREEYRREYEKRESERAKQRERQRQKAIEERRVIYVGKIRPDTTRTEL 693
Query: 322 RERIKGRGNIKSQLCKNANEDGEAALEITQQFKLD 356
R+R + G I+ + N +DG++ IT ++ D
Sbjct: 694 RDRFEVFGEIE-ECTVNLRDDGDSYGFITYRYTCD 727
>PPG1_BOVIN (Q865B7) Peroxisome proliferator activated receptor
gamma coactivator 1 alpha (PPAR gamma coactivator-1
alpha) (PPARGC-1 alpha) (PGC-1 alpha)
Length = 796
Score = 47.8 bits (112), Expect = 5e-05
Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 6/95 (6%)
Query: 267 WDSYEKIQEEMFLLNQIRRTTEK-----AKAKERARTKAEKEARIKAIKKVMLNQKKKDL 321
+DSYE+ Q E + RR EK AK +ER R KA +E R+ + K+ + + +L
Sbjct: 632 YDSYEEYQHERLKREEYRREYEKRESERAKQRERQRQKAIEERRVIYVGKIRPDTTRTEL 691
Query: 322 RERIKGRGNIKSQLCKNANEDGEAALEITQQFKLD 356
R+R + G I+ + N +DG++ IT ++ D
Sbjct: 692 RDRFEVFGEIE-ECTVNLRDDGDSYGFITYRYTCD 725
>INCE_MOUSE (Q9WU62) Inner centromere protein
Length = 880
Score = 47.8 bits (112), Expect = 5e-05
Identities = 55/240 (22%), Positives = 111/240 (45%), Gaps = 29/240 (12%)
Query: 128 RERIK--RRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQ-- 183
R+R++ RR EA E + R+K+ E R +++K K LR+V Q R + ++ +E+
Sbjct: 514 RQRLESLRRKEEA--EQRRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKK 571
Query: 184 -------------IFLSWEQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKE 230
+ E+ +A AKK ++ + ++ K +E+ + LQ EE+E
Sbjct: 572 KQIEQKFAQIDEKTEKAKEERLAEKAKKKATAKKMEEVEARRKQEEEARRLRWLQQEEEE 631
Query: 231 KEKLMAIARAEKFIQSWSECL-AKEAKKGGSGEKELDWDSYEKIQEEMFLLNQIRRTTE- 288
+ + R ++ Q + A+ + E+ + + E+ + E Q R+ E
Sbjct: 632 RRHQEMLQRKKEEEQERRKAAEARRLAEQREQERRREQERREQERREQERREQERKEQER 691
Query: 289 KAKAKERARTKAEKEARIKAIK-------KVMLNQKKKDLRERIKGRGNIKSQLCKNANE 341
+ + +ER R K E + R KA++ K + +K+K+ ++R+ ++ + K A E
Sbjct: 692 REQEQERLRAKREMQEREKALRLQKERLQKELEEKKRKEEQQRL-AEQQLQEEQAKKAKE 750
>TRHY_RABIT (P37709) Trichohyalin
Length = 1407
Score = 47.4 bits (111), Expect = 7e-05
Identities = 57/243 (23%), Positives = 109/243 (44%), Gaps = 34/243 (13%)
Query: 89 EIESLSRKAVKERMRRFKIG--------LANKGRVPWNKGRKHSAETRERIKRRTSEALR 140
E E L ++ +ER+RR + L + + R+ E++ RR + LR
Sbjct: 676 EEEQLLQEREEERLRRQERARKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQLLR 735
Query: 141 EPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGG 200
+ + RK + E + + +E++ R R + ++FRE+ EQ + ++
Sbjct: 736 QERDRK-LREEEQLLQESEEERLRRQEREQQLRRERDRKFREE-----EQLLQEREEERL 789
Query: 201 CGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGS 260
QE K++E+ +QLLQ E+E+E+L R K + +E ++
Sbjct: 790 RRQER-----ERKLREE---EQLLQ--EREEERLRRQERERKLREEEQLLQEREEERLRR 839
Query: 261 GEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKD 320
E+E K++EE Q+ R E+ +ERAR E+E ++ ++ + ++ +
Sbjct: 840 QERE------RKLREE----EQLLRQEEQELRQERARKLREEEQLLRQEEQELRQERDRK 889
Query: 321 LRE 323
LRE
Sbjct: 890 LRE 892
Score = 47.4 bits (111), Expect = 7e-05
Identities = 61/250 (24%), Positives = 115/250 (45%), Gaps = 52/250 (20%)
Query: 89 EIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVRK-K 147
E E L ++ +ER+RR + + RK E R+ ++ E R+ + RK +
Sbjct: 1006 EEEQLLQEREEERLRRQE------------RDRKFREEERQLRRQELEEQFRQERDRKFR 1053
Query: 148 MAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEELD 207
+ E R +EK LRR QER ++FRE+ ++ +++L
Sbjct: 1054 LEEQIR------QEKEEKQLRR--QER--DRKFREE----------EQQRRRQEREQQLR 1093
Query: 208 WDSYNKIKEQLELQQLLQAEEKEK----EKLMAIARAEKFIQSWSECLAKEAKKGGSGEK 263
+ K +E+ +QLLQ E+E+ E+ + E+ ++ + L +E + E+
Sbjct: 1094 RERDRKFREE---EQLLQEREEERLRRQERARKLREEEQLLRREEQLLRQERDRKFREEE 1150
Query: 264 ELDWDSYE----------KIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVM 313
+L +S E K++EE LL + R E+ + +ERAR E+E ++ ++ +
Sbjct: 1151 QLLQESEEERLRRQERERKLREEEQLLQE--REEERLRRQERARKLREEEQLLRQEEQEL 1208
Query: 314 LNQKKKDLRE 323
++ + LRE
Sbjct: 1209 RQERARKLRE 1218
Score = 47.0 bits (110), Expect = 9e-05
Identities = 64/270 (23%), Positives = 119/270 (43%), Gaps = 55/270 (20%)
Query: 89 EIESLSR-KAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVR-K 146
E E L R K +ER R ++ + ++ + K + RER R E +E ++R +
Sbjct: 549 EEEELQREKRRQEREREYR----EEEKLQREEDEKRRRQERERQYRELEELRQEEQLRDR 604
Query: 147 KMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEEL 206
K+ E + ++ +E+ LRR QER + R EQ+ EQ EL
Sbjct: 605 KLREEEQLLQEREEER----LRR--QERERKLREEEQLLRQEEQ--------------EL 644
Query: 207 DWDSYNKIKEQLELQQLLQAEEKE--KEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKE 264
+ K++E+ +QLL+ EE+E +E+ + E+ +Q E + ++
Sbjct: 645 RQERERKLREE---EQLLRREEQELRQERERKLREEEQLLQEREEERLRRQERA------ 695
Query: 265 LDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDLRER 324
K++EE Q+ R E+ +ER R E+E ++ ++++ ++ + LRE
Sbjct: 696 ------RKLREE----EQLLRQEEQELRQERERKLREEEQLLRREEQLLRQERDRKLRE- 744
Query: 325 IKGRGNIKSQLCKNANEDGEAALEITQQFK 354
+ QL + + E+ E QQ +
Sbjct: 745 -------EEQLLQESEEERLRRQEREQQLR 767
Score = 43.5 bits (101), Expect = 0.001
Identities = 63/303 (20%), Positives = 128/303 (41%), Gaps = 56/303 (18%)
Query: 89 EIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVRKKM 148
E E L ++ +ER+RR + + E + ++ R E LR + +K+
Sbjct: 776 EEEQLLQEREEERLRR-------------QERERKLREEEQLLQEREEERLRRQERERKL 822
Query: 149 AEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEELDW 208
E + ++ +E+ LRR QER + R EQ+ EQ + + +E+L
Sbjct: 823 REEEQLLQEREEER----LRR--QERERKLREEEQLLRQEEQELRQERARKLREEEQLLR 876
Query: 209 DSYNKIKEQL-----ELQQLLQAEEKE--KEKLMAIARAEKFIQSWSE----------CL 251
+++++ E +QLL+ EE+E +E+ + E+ +Q E L
Sbjct: 877 QEEQELRQERDRKLREEEQLLRQEEQELRQERDRKLREEEQLLQESEEERLRRQERERKL 936
Query: 252 AKEAKKGGSGEKELDWDSYEKIQEEMFLLN--------------------QIRRTTEKAK 291
+E + E+EL + K++EE LL Q+ R E+
Sbjct: 937 REEEQLLRREEQELRRERARKLREEEQLLQEREEERLRRQERARKLREEEQLLRREEQEL 996
Query: 292 AKERARTKAEKEARIKAIKKVMLNQKKKDLRERIKGRGNIKSQLCKNANEDGEAALEITQ 351
+ER R E+E ++ ++ L ++++D + R + R + +L + ++ + + +
Sbjct: 997 RQERDRKFREEEQLLQEREEERLRRQERDRKFREEERQLRRQELEEQFRQERDRKFRLEE 1056
Query: 352 QFK 354
Q +
Sbjct: 1057 QIR 1059
Score = 43.5 bits (101), Expect = 0.001
Identities = 68/275 (24%), Positives = 124/275 (44%), Gaps = 46/275 (16%)
Query: 88 LEIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETR---ERIKRRTSEALREPKV 144
L + L + +ER R+F++ + + R+ + + E +RR E RE ++
Sbjct: 1035 LRRQELEEQFRQERDRKFRLEEQIRQEKEEKQLRRQERDRKFREEEQQRRRQE--REQQL 1092
Query: 145 RKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQE 204
R++ R ++E+ LRR QER + R EQ+ EQ + ++
Sbjct: 1093 RRERDRKFREEEQLLQEREEERLRR--QERARKLREEEQLLRREEQLL----------RQ 1140
Query: 205 ELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKE 264
E D K +E+ +QLLQ E E+E+L R K + E L +E ++ E+
Sbjct: 1141 ERD----RKFREE---EQLLQ--ESEEERLRRQERERKLREE--EQLLQEREE----ERL 1185
Query: 265 LDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDLRER 324
+ K++EE Q+ R E+ +ERAR E+E +L Q++++LR+
Sbjct: 1186 RRQERARKLREE----EQLLRQEEQELRQERARKLREEEQ--------LLRQEEQELRQE 1233
Query: 325 IKGRGNIKSQLCKNANEDGEAALEITQQFKLDTKL 359
+ + QL + E+ E E ++F+ + +L
Sbjct: 1234 RDRKFREEEQLLR--REEQELRRERDRKFREEEQL 1266
Score = 36.2 bits (82), Expect = 0.16
Identities = 38/191 (19%), Positives = 89/191 (45%), Gaps = 29/191 (15%)
Query: 137 EALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAA 196
E E + RKK + +S + ++K +R+ ++ L+ +R E+
Sbjct: 145 ELAEEEEQRKKRERFEQHYSRQYRDKE----QRLQRQELEERRAEEE----------QLR 190
Query: 197 KKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAK 256
++ G EE + + +EQ EL++ L+ EE+++ + + E+ +Q E L ++ +
Sbjct: 191 RRKGRDAEEFIEEEQLRRREQQELKRELREEEQQRRERR--EQHERALQEEEEQLLRQRR 248
Query: 257 KGGSGEKELDWDSYEKIQEEMFL-LNQIRRTTEKAKAKERARTKAEKEARI--KAIKKVM 313
W + Q+++ L +IR ++ + +ER + +E R+ + ++
Sbjct: 249 ----------WREEPREQQQLRRELEEIREREQRLEQEERREQQLRREQRLEQEERREQQ 298
Query: 314 LNQKKKDLRER 324
L ++ +++RER
Sbjct: 299 LRRELEEIRER 309
>INCE_HUMAN (Q9NQS7) Inner centromere protein
Length = 919
Score = 47.4 bits (111), Expect = 7e-05
Identities = 67/279 (24%), Positives = 116/279 (41%), Gaps = 45/279 (16%)
Query: 112 KGRVPWNKGRKHSAETRERIKRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVW 171
K P K R RR EA E R+K+ E R +++K K LR+V
Sbjct: 521 KRNTPLRMDPKEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRLEEVKLKREERLRKVL 578
Query: 172 QERLKSKRFREQIFLSWEQCIANAAKKGGCGQEE-------------------------- 205
Q R + ++ +E+ EQ A +K +EE
Sbjct: 579 QARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQE 638
Query: 206 -----LDWDSYNKIKEQLELQQLLQ-AEEKEKEKLMAIARAEKFI----QSWSECLAKEA 255
L W + +E+ Q+LLQ +E+E+E+L A A++ Q E +E
Sbjct: 639 EDARRLRW--LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 696
Query: 256 KKGGSGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARI--KAIKKVM 313
++ +E + E+ ++E L Q RR ++ ER + EK R+ + +++ +
Sbjct: 697 ERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQREL 756
Query: 314 LNQKKKDLRERIKGRGNIKSQLCKNANEDGEA--ALEIT 350
+KKK+ ++R+ R ++ + K A E A AL +T
Sbjct: 757 EEKKKKEEQQRLAER-QLQEEQEKKAKEAAGASKALNVT 794
>CALD_CHICK (P12957) Caldesmon (CDM)
Length = 771
Score = 47.0 bits (110), Expect = 9e-05
Identities = 60/265 (22%), Positives = 116/265 (43%), Gaps = 35/265 (13%)
Query: 95 RKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVRKKMAEHPRF 154
RKA +ER + + A + R K RK +AE RER K + E K R
Sbjct: 340 RKAAEERAKAEEERKAAEERAKAEKERK-AAEERERAKAEEEKRAAEEKAR--------L 390
Query: 155 HSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQE-----ELDWD 209
++K+KEK ++ +E+ ++ R+Q ++ AKK ++ + D
Sbjct: 391 EAEKLKEKKKMEEKKAQEEKAQANLLRKQ---EEDKEAKVEAKKESLPEKLQPTSKKDQV 447
Query: 210 SYNKIKEQLELQQLLQAEEKEK----------EKLMAIARAEKFIQSWSECLAKEAKKGG 259
NK KE+ +++ ++++ E+ + + + ++ K A
Sbjct: 448 KDNKDKEKAPKEEMKSVWDRKRGVPEQKAQNGERELTTPKLKSTENAFGRSNLKGAANAE 507
Query: 260 SGEKELDWDSYEKIQEEMFLLNQI-RRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKK 318
+G ++L EK QE L+++ +R E+ K E K ++E +A +K+ ++K
Sbjct: 508 AGSEKLK----EKQQEAAVELDELKKRREERRKILEEEEQKKKQE---EAERKIREEEEK 560
Query: 319 KDLRERIKGRGNIKSQLCKNANEDG 343
K ++E I+ R ++ + EDG
Sbjct: 561 KRMKEEIERRRAEAAEKRQKVPEDG 585
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/224 (22%), Positives = 94/224 (41%), Gaps = 14/224 (6%)
Query: 156 SDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEELDWDSYNKIK 215
+DK KE+ ++ E + + E+ + E+ A KK +E + +
Sbjct: 241 ADKEKEEAEKEREKLEAEEKERLKAEEEKKAAEEKQKAEEEKKAAEERERAKAEEEKRAA 300
Query: 216 EQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKELDWDSYEKIQE 275
E+ E + + + +E+ A A E+ +E AK ++ + E+ + K E
Sbjct: 301 EERERAKAEEERKAAEERERAKAEEER---KAAEERAKAEEERKAAEERAKAEEERKAAE 357
Query: 276 EMFLLNQIRRTTEKAKAKERARTKAEKEARI---KAIKKVMLNQKKKDLRERIKGRGNIK 332
E + + E+ A+ER R KAE+E R KA + ++KK + E+ +
Sbjct: 358 E-----RAKAEKERKAAEERERAKAEEEKRAAEEKARLEAEKLKEKKKMEEKKAQEEKAQ 412
Query: 333 SQLCKNANEDGEAALEITQQF---KLDTKLTKINISKNINSEVA 373
+ L + ED EA +E ++ KL K + N + E A
Sbjct: 413 ANLLRKQEEDKEAKVEAKKESLPEKLQPTSKKDQVKDNKDKEKA 456
Score = 42.7 bits (99), Expect = 0.002
Identities = 56/268 (20%), Positives = 108/268 (39%), Gaps = 15/268 (5%)
Query: 122 KHSAETRERIKRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFR 181
K AE +ER K E R +K A + +++ K+ R +E ++ R
Sbjct: 245 KEEAE-KEREKLEAEEKERLKAEEEKKAAEEKQKAEEEKKAAEERERAKAEEEKRAAEER 303
Query: 182 EQIFLSWEQCIANAAKKGGCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAE 241
E+ E+ A ++ +E + K +E+ + + E+E++ A+AE
Sbjct: 304 ERAKAEEERKAAEERERAKAEEERKAAEERAKAEEERKAAEERAKAEEERKAAEERAKAE 363
Query: 242 KFIQSWSE---CLAKEAKKGGSGEKELDWDSY--------EKIQEEMFLLNQIRRTTEKA 290
K ++ E A+E K+ + L+ + +K QEE N +R+ E
Sbjct: 364 KERKAAEERERAKAEEEKRAAEEKARLEAEKLKEKKKMEEKKAQEEKAQANLLRKQEEDK 423
Query: 291 KAKERARTKAEKEARIKAIKKVML---NQKKKDLRERIKGRGNIKSQLCKNANEDGEAAL 347
+AK A+ ++ E KK + K+K +E +K + K + + ++GE L
Sbjct: 424 EAKVEAKKESLPEKLQPTSKKDQVKDNKDKEKAPKEEMKSVWDRKRGVPEQKAQNGEREL 483
Query: 348 EITQQFKLDTKLTKINISKNINSEVARE 375
+ + + N+ N+E E
Sbjct: 484 TTPKLKSTENAFGRSNLKGAANAEAGSE 511
>M18A_MOUSE (Q9JMH9) Myosin XVIIIA (Myosin 18A) (Myosin containing PDZ
domain)
Length = 2035
Score = 46.6 bits (109), Expect = 1e-04
Identities = 54/289 (18%), Positives = 131/289 (44%), Gaps = 30/289 (10%)
Query: 84 LSDSLEIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPK 143
L D +E+E SR+ ++ R+ + ++ ++ + +++ +R T+E L++ K
Sbjct: 1389 LEDKMEVEQQSRRQLERRLGDL--------QADSDESQRALQQLKKKCQRLTAE-LQDTK 1439
Query: 144 VRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANA-AKKGGCG 202
+ + + +K + + L + +E + K RE++ + +A A + K
Sbjct: 1440 LHLEGQQVRNHELEKKQRRFDSELSQAHEETQREKLQREKLQREKDMLLAEAFSLKQQME 1499
Query: 203 QEELDWDSYNK--IKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGS 260
+++LD + + + + ELQ + E K++ L + + + +++ K
Sbjct: 1500 EKDLDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEA----------KVKD 1549
Query: 261 GEKELDWD--SYEKIQEEMFLLNQIRRTTEKAKAKE-RARTKAEKEARIKAIKK-----V 312
E+ELD S + +++ L + +KE +R + +EAR KK V
Sbjct: 1550 QEEELDEQAGSIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEV 1609
Query: 313 MLNQKKKDLRERIKGRGNIKSQLCKNANEDGEAALEITQQFKLDTKLTK 361
L ++ +D ++ ++ + ++S+L +++ + E ++ + D K TK
Sbjct: 1610 QLEEEYEDKQKALREKRELESKLSTLSDQVNQRDFESEKRLRKDLKRTK 1658
>YLX8_CAEEL (P46504) Hypothetical protein F23F12.8 in chromosome III
precursor
Length = 887
Score = 46.2 bits (108), Expect = 2e-04
Identities = 54/237 (22%), Positives = 115/237 (47%), Gaps = 23/237 (9%)
Query: 128 RERIKRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLS 187
+ER+ + L ++ +K E+ R ++I +IS +R + + +L+ +R E++
Sbjct: 363 QERMAMERNRELERIRLEEKKRENERVRQEEIAMEIS-KIRELERLQLERQRKNERVRQE 421
Query: 188 WEQCIANAAKKGGCGQEELDWDSYNKIKEQ-LELQQLLQAEEKEKEKLMAIA--RAEKFI 244
E AA+K +EE KI++Q +E++Q+ Q EE +E+L + RA +
Sbjct: 422 LE-----AARKYKLQEEERQ----RKIQQQKVEMEQIRQQEEARQEQLRVLEEERARELE 472
Query: 245 QSWSECLAKEAKKGGSGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEA 304
+ E L ++ + ++E D +K++++ R E+ +A+E R EKE
Sbjct: 473 RVRQEELERQHQMEILRQQEED-QKKKKLEKD-------REQREQQEAEELNRMIIEKEM 524
Query: 305 RIKAIKKVMLNQKKKDLRERIKGRGN--IKSQLCKNANEDGEAALEITQQFKLDTKL 359
+ K + K+K L + ++ R N + + + A E+ +EI ++ ++ ++
Sbjct: 525 KENKQKMIEEKNKRKMLEKEMEDRQNAIYEEEERRIAEEERRKQIEIEERRRIQQQI 581
>PLE1_HUMAN (Q15149) Plectin 1 (PLTN) (PCN) (Hemidesmosomal protein 1)
(HD1)
Length = 4684
Score = 45.8 bits (107), Expect = 2e-04
Identities = 83/400 (20%), Positives = 159/400 (39%), Gaps = 61/400 (15%)
Query: 54 QINVDDDSDNQSETSVDSSDYLNGGDGVVGLSDSLEIESLSRKAVKERMRRFKIGLANKG 113
Q+ +D + ++E ++ L L EI ++A ER+RR A +
Sbjct: 1955 QLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQR 2014
Query: 114 RVPWNKGRKHSAETRERIKRRTSEALREPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQE 173
R + +H A+ ER+ + + E + +K + E +++E+I +L+ +++
Sbjct: 2015 RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI-LALKASFEK 2073
Query: 174 RLKSK--------RFR---EQIFLSWEQCIANAAKKGGCGQEE----------------L 206
K R R E S EQ AA++ EE
Sbjct: 2074 AAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAA 2133
Query: 207 DWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQ------SWSECLAKEAKKGGS 260
+ ++ + K LE + L+A+ +E L A E Q + + L E K
Sbjct: 2134 EEEAARQRKAALEEVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRLQAEEKAHAF 2193
Query: 261 GEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKD 320
++ + + + +Q+E +L+++R +A+A RA +AE EAR++A ++ ++++ +
Sbjct: 2194 AVQQKEQELQQTLQQEQSVLDRLR---GEAEAARRAAEEAE-EARVQAEREAAQSRRQVE 2249
Query: 321 LRERIKGRGNIKSQLCKNANEDGEAALEITQQFKLDTKLTKINISKNINSEVAREGGFSN 380
ER+K ++Q A +AA E + K E AR
Sbjct: 2250 EAERLKQSAEEQAQ----ARAQAQAAAE--------------KLRKEAEQEAARRAQAEQ 2291
Query: 381 SIYPTYNKLDLEVIKREK-----LRKEASFADRIQAARLK 415
+ D E+ K +K LR++A + RL+
Sbjct: 2292 AALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQ 2331
Score = 38.9 bits (89), Expect = 0.025
Identities = 63/304 (20%), Positives = 123/304 (39%), Gaps = 52/304 (17%)
Query: 89 EIESLSRKAVKERMRRFKIGLANKGR---VPWNKGRKHSAETRERIKRRTSE---ALREP 142
E E +A ER R+ ++ L R R AE +++R E A+ +
Sbjct: 1684 EAERWLCQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1743
Query: 143 KVRKKMAEHPRFHSDKIKEKISYSLRRVWQ----ERLKSKRFREQIFLSWEQCIANAAKK 198
+ + + +++ +E+ L R WQ E L+ + E++ A A K+
Sbjct: 1744 REEAERRAQQQAEAERAREEAERQLER-WQLKANEALRLRLQAEEVLQQKSLAQAEAEKQ 1802
Query: 199 GGCGQEELDWDSYN--KIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAK 256
+EE + ++ K +EQ Q+ L +E EK++ +A A++ + + E + A+
Sbjct: 1803 ----KEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAE 1858
Query: 257 -KGGSGEKELDWDSYEKIQEEMFLLNQIRRTTE----------------KAKAKERARTK 299
+ G +++L + ++Q E Q R+ E KAKA+E +R+
Sbjct: 1859 TEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAKAEEESRST 1918
Query: 300 AEKE------------------ARIKAIKKVMLNQKKKDLRERIKGRGNIKSQLCKNANE 341
+EK AR++A+ + Q++ + + R + L +
Sbjct: 1919 SEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAA 1978
Query: 342 DGEA 345
GEA
Sbjct: 1979 IGEA 1982
Score = 35.4 bits (80), Expect = 0.28
Identities = 66/324 (20%), Positives = 139/324 (42%), Gaps = 31/324 (9%)
Query: 46 RVLSIEELQINVDDDSDNQSETSVDSSDYLNGGDGV----VGLSDSLEIESLSRKAVKER 101
RV + Q ++D+ + + + + L+ + V L +LEI+ ER
Sbjct: 2525 RVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER 2584
Query: 102 MR-------RFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVRKK--MAEHP 152
+R R K L + ++ K + +E++ + T +AL++ + +K + +
Sbjct: 2585 LREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET-QALQQSFLSEKDSLLQRE 2643
Query: 153 RF---HSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANA--AKKGGCGQEE-- 205
RF K+++ + + Q R + +R ++Q+ ++ +A+ A++ EE
Sbjct: 2644 RFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGV 2703
Query: 206 -LDWDSYNKIKEQLELQQLLQAEEKEK--EKLMAIARAEKFIQSWSECLAKE----AKKG 258
+ ++++Q Q+ L AEE ++ E+L + + + SE + K
Sbjct: 2704 RRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2763
Query: 259 GSGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARI-KAIKKVMLNQK 317
+G LD + E E F + +RR + +E AE+ R+ + V +
Sbjct: 2764 PNGRDALDGPAAEAEPEHSF--DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELAR 2821
Query: 318 KKDLRERIKGRGNIKSQLCKNANE 341
++D+R ++GR +I L K NE
Sbjct: 2822 REDVRHYLQGRSSIAGLLLKATNE 2845
Score = 35.4 bits (80), Expect = 0.28
Identities = 54/305 (17%), Positives = 121/305 (38%), Gaps = 26/305 (8%)
Query: 53 LQINVDDDSDNQSETSVDSSDYLNGGDGVVGLSDSLEIESLSRK---AVKERMRRFKIGL 109
L+ + + + ++E ++ + + + + E+E+ ++ A +ER RR
Sbjct: 2067 LKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 2126
Query: 110 ANKGRVPWNKG---RKHSAETRERIKRRTSEA----------------LREPKVRKKMAE 150
K + RK + E ER+K + EA L + +K++
Sbjct: 2127 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRLQA 2186
Query: 151 HPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKGGCGQEELDWDS 210
+ H+ +++K + + QE+ R R + + + A A++ E S
Sbjct: 2187 EEKAHAFAVQQKEQELQQTLQQEQSVLDRLRGEAEAA--RRAAEEAEEARVQAEREAAQS 2244
Query: 211 YNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKELDWDSY 270
+++E L+Q AEE+ + + A A AEK + + A+ A+ + ++
Sbjct: 2245 RRQVEEAERLKQ--SAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA 2302
Query: 271 EKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDLRERIKGRGN 330
E + + F +R+ + + R + E+ K + L + K + E + R
Sbjct: 2303 EMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ 2362
Query: 331 IKSQL 335
++ +L
Sbjct: 2363 VEEEL 2367
Score = 34.3 bits (77), Expect = 0.61
Identities = 35/159 (22%), Positives = 78/159 (49%), Gaps = 18/159 (11%)
Query: 209 DSYNKIKEQLELQQLLQAEEKEK--------EKLMAIARAEKFIQSWSECLAKEAKKGGS 260
++ +++E+ L + +AEE+E+ EK +A A ++ +E AKE ++
Sbjct: 1476 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRIQ 1535
Query: 261 GE----KELDWDSYEK---IQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVM 313
E +E D+ ++ IQEE L Q+R+++E + + +A + +R++ +++
Sbjct: 1536 EEVVRREEAAVDAQQQKRSIQEE---LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1592
Query: 314 LNQKKKDLRERIKGRGNIKSQLCKNANEDGEAALEITQQ 352
+ + + + ER +G + Q + E+ EA Q+
Sbjct: 1593 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1631
Score = 32.3 bits (72), Expect = 2.3
Identities = 64/287 (22%), Positives = 121/287 (41%), Gaps = 25/287 (8%)
Query: 86 DSLEIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPKVR 145
D+L E + V ER+++ + G + W + E + + +T RE +
Sbjct: 1284 DALRDELRGAQEVGERLQQ-RHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQL 1342
Query: 146 KKMAEHPRFHSDKIKEKISYSLRRVWQERLK------SKRFREQIFLSWEQCIANAAKKG 199
+ + R +D + + + RR QE+++ S+ REQ L EQ + ++
Sbjct: 1343 GRQLRYYRESADPLGAWLQDARRR--QEQIQAMPLADSQAVREQ--LRQEQALLEEIERH 1398
Query: 200 GCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGG 259
G EE + I + + L + + E + + A+ K +QS SE + +E
Sbjct: 1399 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPK-VQSGSESVIQEYVDLR 1457
Query: 260 SGEKELDW--DSYEK-IQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIK--------- 307
+ EL Y K I E + + + R E+ +A+ER R AE EA ++
Sbjct: 1458 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERL-AEVEAALEKQRQLAEAH 1516
Query: 308 AIKKVMLNQKKKDLRERIKGRGNIKSQLCKNANEDGEAALEITQQFK 354
A K ++ K+L++RI+ + + +A + + E QQ +
Sbjct: 1517 AQAKAQAEREAKELQQRIQEEVVRREEAAVDAQQQKRSIQEELQQLR 1563
Score = 32.0 bits (71), Expect = 3.0
Identities = 42/194 (21%), Positives = 83/194 (42%), Gaps = 28/194 (14%)
Query: 213 KIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKELDWDSYEK 272
K E L L+ LQAEE ++K +A A AEK E +EA++ G E+ +
Sbjct: 1774 KANEALRLR--LQAEEVLQQKSLAQAEAEK----QKEEAEREARRRGKAEE-------QA 1820
Query: 273 IQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDLRERIKGRGNIK 332
+++ ++ + + A+ + R AE+E + Q+++ L E +
Sbjct: 1821 VRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL------- 1873
Query: 333 SQLCKNANEDGEAALEITQQFKLDTKLTKINISKNI--NSEVAREGGFSNSIYPTYNKLD 390
A EAA ++ +L+ +L K+ + S+ E ++ + +L+
Sbjct: 1874 ------ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAKAEEESRSTSEKSKQRLE 1927
Query: 391 LEVIKREKLRKEAS 404
E + +L +EA+
Sbjct: 1928 AEAGRFRELAEEAA 1941
>FAU_DROME (Q9VGX3) Anoxia up-regulated protein
Length = 619
Score = 45.4 bits (106), Expect = 3e-04
Identities = 59/267 (22%), Positives = 118/267 (44%), Gaps = 20/267 (7%)
Query: 84 LSDSLEIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAETRERIKRRTSEALREPK 143
L D L++E+ K+R+R+ ++ N+ + K A+ + KRR AL+E +
Sbjct: 298 LEDPLDVEAKE----KQRLRQERLLTVNEEALDEVDLEKKRAQKADEAKRREERALKEER 353
Query: 144 VRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWE--QCIANAAKKGGC 201
R AE + + K K+ + + +E L ++ ++ + + +AA+K
Sbjct: 354 DR-LTAEAEKQAAAKAKKAAEEAAKIAAEEALLAEAAAQKAAEEAKALKAAEDAAQKAAE 412
Query: 202 GQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGSG 261
+ + K+ E+ + E+ +L A A+K + ++ A+EA +
Sbjct: 413 EARLAEEAAAQKVAEE------AAQKAAEEARLAEEAAAQKAAEEAAQKAAEEAALKAAE 466
Query: 262 EKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQ--KKK 319
E L ++ +K EE L + E+A+A E A KA +EAR+ ++ Q +++
Sbjct: 467 EARLAEEAAQKAAEEAAL-----KAVEEARAAEEAAQKAAEEARVAEEARLEEEQRVREQ 521
Query: 320 DLRERIKGRGNIKSQLCKNANEDGEAA 346
+L + + +L + A E E A
Sbjct: 522 ELERLAEIEKESEGELARQAAELAEIA 548
>ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog
(X-linked nuclear protein-1)
Length = 1359
Score = 45.4 bits (106), Expect = 3e-04
Identities = 49/209 (23%), Positives = 91/209 (43%), Gaps = 19/209 (9%)
Query: 209 DSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGGSGEKELDWD 268
DS + E +L+ Q E + KEK + ++ + + AKK + E D D
Sbjct: 10 DSDGHVIEDEDLEMARQIENERKEKRAQKLKEKREREGKPPPKKRPAKKRKASSSEEDDD 69
Query: 269 SYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDLRERIKGR 328
E+ + +++ ++AK++ + E+E R K+ K ++QKKK+
Sbjct: 70 DEEESPRK-----SSKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQKKKE-------- 116
Query: 329 GNIKSQLCKNANEDGEAALEITQQFKLDTKLTKINISKNINSEVAREGGFSNSIYPTYNK 388
K + +++ED ++ E Q+ K +K TK K +SE + E + +
Sbjct: 117 -KSKKKRTTSSSEDEDSDEEREQKSKKKSKKTK----KQTSSESSEESEEERKVKKSKKN 171
Query: 389 LDLEVIKREKLRKEASFADRIQAARLKKG 417
+ V KR + +E S D + + KKG
Sbjct: 172 KEKSVKKRAETSEE-SDEDEKPSKKSKKG 199
Score = 39.3 bits (90), Expect = 0.019
Identities = 53/269 (19%), Positives = 102/269 (37%), Gaps = 35/269 (13%)
Query: 84 LSDSLEIESLSRKAVKERMRRFKIGLANKGRVPWNKGRKHSAET----RERIKRRTSEAL 139
++ +E E ++A K + +R + G + P K + S+E E R++S+
Sbjct: 23 MARQIENERKEKRAQKLKEKREREGKPPPKKRPAKKRKASSSEEDDDDEEESPRKSSKKS 82
Query: 140 REPKVRKKMAEHPRFHSDKIKEKISYSLRRVWQERLKSKRFREQIFLSWEQCIANAAKKG 199
R+ + ++ D+ K K + + +E+ K KR ++ +
Sbjct: 83 RKRAKSESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKR-------------TTSSSED 129
Query: 200 GCGQEELDWDSYNKIKEQLELQQLLQAEEKEKEKLMAIARAEKFIQSWSECLAKEAKKGG 259
EE + S K K+ + +EE E+E+ + ++ K K KK
Sbjct: 130 EDSDEEREQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNK---------EKSVKKRA 180
Query: 260 SGEKELDWDSYEKIQEEMFLLNQIRRTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKK 319
+E D D + + L K KAK + +++E E +K KK KK
Sbjct: 181 ETSEESDEDEKPSKKSKKGL---------KKKAKSESESESEDEKEVKKSKKKSKKVVKK 231
Query: 320 DLRERIKGRGNIKSQLCKNANEDGEAALE 348
+ + K++ K + E + E
Sbjct: 232 ESESEDEAPEKKKTEKRKRSKTSSEESSE 260
>PPG1_MOUSE (O70343) Peroxisome proliferator activated receptor
gamma coactivator 1 alpha (PPAR gamma coactivator-1
alpha) (PPARGC-1 alpha) (PGC-1 alpha)
Length = 797
Score = 45.1 bits (105), Expect = 3e-04
Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 6/95 (6%)
Query: 267 WDSYEKIQEEMFLLNQIR-----RTTEKAKAKERARTKAEKEARIKAIKKVMLNQKKKDL 321
+DSYE + E ++ R R +E+AK +ER + KA +E R+ + K+ + + +L
Sbjct: 633 YDSYEAYEHERLKRDEYRKEHEKRESERAKQRERQKQKAIEERRVIYVGKIRPDTTRTEL 692
Query: 322 RERIKGRGNIKSQLCKNANEDGEAALEITQQFKLD 356
R+R + G I+ + N +DG++ IT ++ D
Sbjct: 693 RDRFEVFGEIE-ECTVNLRDDGDSYGFITYRYTCD 726
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.313 0.130 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,765,660
Number of Sequences: 164201
Number of extensions: 1852129
Number of successful extensions: 8151
Number of sequences better than 10.0: 362
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 344
Number of HSP's that attempted gapping in prelim test: 7325
Number of HSP's gapped (non-prelim): 819
length of query: 420
length of database: 59,974,054
effective HSP length: 113
effective length of query: 307
effective length of database: 41,419,341
effective search space: 12715737687
effective search space used: 12715737687
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Lotus: description of TM0340.11