BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= TM0135.11
(664 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
NUCL_XENLA (P20397) Nucleolin (Protein C23) 238 3e-62
GAR2_SCHPO (P41891) Protein gar2 231 6e-60
NUCL_CHICK (P15771) Nucleolin (Protein C23) 211 5e-54
NUCL_MESAU (P08199) Nucleolin (Protein C23) 203 1e-51
NUCL_RAT (P13383) Nucleolin (Protein C23) 195 3e-49
NUCL_MOUSE (P09405) Nucleolin (Protein C23) 189 3e-47
NUCL_HUMAN (P19338) Nucleolin (Protein C23) 184 6e-46
NSR1_YEAST (P27476) Nuclear localization sequence binding protei... 181 7e-45
NP14_HUMAN (Q14978) Nucleolar phosphoprotein p130 (Nucleolar 130... 173 1e-42
NP14_RAT (P41777) Nucleolar phosphoprotein p130 (Nucleolar 130 k... 162 2e-39
ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog (X-li... 129 2e-29
NFH_HUMAN (P12036) Neurofilament triplet H protein (200 kDa neur... 125 5e-28
DSPP_HUMAN (Q9NZW4) Dentin sialophosphoprotein precursor [Contai... 120 9e-27
SR40_YEAST (P32583) Suppressor protein SRP40 120 1e-26
DSPP_MOUSE (P97399) Dentin sialophosphoprotein precursor (Dentin... 114 1e-24
NFH_MOUSE (P19246) Neurofilament triplet H protein (200 kDa neur... 112 3e-24
RO32_XENLA (P51992) Heterogeneous nuclear ribonucleoprotein A3 h... 110 9e-24
ROA1_MACMU (Q28521) Heterogeneous nuclear ribonucleoprotein A1 (... 110 1e-23
ROA3_RAT (Q6URK4) Heterogeneous nuclear ribonucleoprotein A3 (hn... 108 3e-23
ROA3_MOUSE (Q8BG05) Heterogeneous nuclear ribonucleoprotein A3 (... 108 3e-23
>NUCL_XENLA (P20397) Nucleolin (Protein C23)
Length = 650
Score = 238 bits (608), Expect = 3e-62
Identities = 204/685 (29%), Positives = 312/685 (44%), Gaps = 103/685 (15%)
Query: 39 QVSAKKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSED-EKPAPKVAPLKTSV------ 91
+ AK +K A K ++++ ++E +DDSS E+ E P K KT+
Sbjct: 8 KTQAKPKKAAPPPPKDMEDSE----EEEDMEEDDSSDEEVEVPVKKTPAKKTATPAKATP 63
Query: 92 -------KNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSS 144
K G TPAK K A S+E+ D +EE +KP K K+ + E+S
Sbjct: 64 GKAATPGKKGATPAKNGKQA-KKQESEEEEDDSDEEAEDQKPIKNKPVAKKAVAKKEESE 122
Query: 145 SDEDSSSESDDEKPAAKVAVPAKK-----------------------APAKNGSVTAPAK 181
D+D ES++EK AK PAKK APA G TA A
Sbjct: 123 EDDDDEDESEEEKAVAKKPTPAKKPAGKKQESEEEDDEESEDEPMEVAPALKGKKTAQAA 182
Query: 182 KAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSD---------DSS 232
+ + EDDD EE + SAK+ K+ P +K K +++S+ +S+
Sbjct: 183 EEDDEEEDDDDEEDDDDEEEQQGSAKRKKEMPKTIPEAKKTKTDTASEGLSIFIGNLNST 242
Query: 233 SESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAA 292
E ++ K A++ K + D SS+E+ +K A K+ K
Sbjct: 243 KEFDELKDALREFFSKKNLTIQDIRIGNSKKFGYVDFSSEEEVEK---ALKLTGKKILGT 299
Query: 293 PIKKVEKSESSDDESSESSDEENDSK-------PATTTVAKPSAVKKSASSDSDDEDSSD 345
+K +EK+ + D + + +E DS+ P +TTV + + ++A
Sbjct: 300 EVK-IEKAMAFDKNKTAENKKERDSRTLFVKNIPYSTTVEELQEIFENAK---------- 348
Query: 346 SDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVE----MVDASSGKNAPKTPAA 401
D + K ++ + + EDE + +K+ ++E VD + K+
Sbjct: 349 -DIRIPTGKDGSNKGIAYVEFSNEDEANKALEEKQGAEIEGRSIFVDFTGEKSQNSGNKK 407
Query: 402 QTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATDEDGRFKGFGHVEFATAAA 461
E + SK L V NLS+S + F+ + +R+ ++ GR KGF +EF++A
Sbjct: 408 GPEGD-SKVLVVNNLSYSATEDSLREVFE---KATSIRIPQNQ-GRAKGFAFIEFSSAED 462
Query: 462 AQSALEY-NGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRGQSQTVFVRGFDKFQ 520
A+ A++ N +E+ R +RL+ ++ G P G +GG QS+T+FVRG
Sbjct: 463 AKDAMDSCNNTEIEGRSIRLEFSQGGG---PQGGG------RGGSAQSKTLFVRGLS--- 510
Query: 521 GEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVNKALE-LHDSDLG 579
ED + +L+E F + D ++G KGF ++DFS A E + D ++
Sbjct: 511 -EDTTEETLKEAFDGS---VNARIVTDRDTGASKGFGFVDFSTAEDAKAAKEAMEDGEID 566
Query: 580 GFTLAVDEAKPRDNQGSGGRSGGGRSGGGRGGRFDSGRGGGRGRFGSGGRGGDRGGRGGR 639
G + +D AKP+ + GGR G GR GG RGGR G GGGRG FG G G RGG GGR
Sbjct: 567 GNKVTLDFAKPKGDSQRGGRGGFGRGGGFRGGRGGRGGGGGRG-FGGRGGGRGRGGFGGR 625
Query: 640 GGGG-RGGRGTPLR-AEGKKTTFAD 662
GGGG RGG+G R +GKK F D
Sbjct: 626 GGGGFRGGQGGGFRGGQGKKMRFDD 650
Score = 143 bits (360), Expect = 2e-33
Identities = 148/542 (27%), Positives = 220/542 (40%), Gaps = 141/542 (26%)
Query: 171 AKNGSVTAPAKKAQPAPSSSSES--------EDDDSSEEDE-PSAKQPKKEVA------- 214
AK A KKA P P E EDD S EE E P K P K+ A
Sbjct: 4 AKGAKTQAKPKKAAPPPPKDMEDSEEEEDMEEDDSSDEEVEVPVKKTPAKKTATPAKATP 63
Query: 215 -------------VKPAVQKKKEES--SSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGA 259
K Q KK+ES DDS E+ED+KP K P A K A
Sbjct: 64 GKAATPGKKGATPAKNGKQAKKQESEEEEDDSDEEAEDQKPI-------KNKPVAKKAVA 116
Query: 260 ADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSKP 319
+S + D DE +++K A K PA P K ++SE DDE ES DE + P
Sbjct: 117 KKEESEEDDDDEDESEEEKAVA---KKPTPAKKPAGKKQESEEEDDE--ESEDEPMEVAP 171
Query: 320 ATTTVAKPSAVKKSASSDSDDEDSSDSDS------------------EVKKDKMD----- 356
A A ++ + DD++ D D E KK K D
Sbjct: 172 ALKGKKTAQAAEEDDEEEDDDDEEDDDDEEEQQGSAKRKKEMPKTIPEAKKTKTDTASEG 231
Query: 357 ----------VDESDSSED------------------------------SDEEDEKSTKT 376
E D +D S+EE EK+ K
Sbjct: 232 LSIFIGNLNSTKEFDELKDALREFFSKKNLTIQDIRIGNSKKFGYVDFSSEEEVEKALKL 291
Query: 377 PQKKVKDVEM-VDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEV 435
KK+ E+ ++ + + KT + E + S+TLFV N+ +S +++ F++
Sbjct: 292 TGKKILGTEVKIEKAMAFDKNKTAENKKERD-SRTLFVKNIPYSTTVEELQEIFEN---A 347
Query: 436 VDVRLATDEDGRFKGFGHVEFATAAAAQSAL-EYNGSELLQRPVRLDLARERGAYTPNSG 494
D+R+ T +DG KG +VEF+ A AL E G+E+ R + +D E+
Sbjct: 348 KDIRIPTGKDGSNKGIAYVEFSNEDEANKALEEKQGAEIEGRSIFVDFTGEK-------- 399
Query: 495 AANNSFQKGGRGQSQTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFESGNVK 554
+ N+ +KG G S+ + V ED SL+E F + T I +P++ G K
Sbjct: 400 SQNSGNKKGPEGDSKVLVVNNLSYSATED----SLREVF---EKATSIRIPQN--QGRAK 450
Query: 555 GFAYLDFSDTNSVNKALE-LHDSDLGGFTLAVDEAKPRDNQGSGGRSGGGRSGGGRGGRF 613
GFA+++FS A++ +++++ G ++ ++ ++ GGG GGGRGG
Sbjct: 451 GFAFIEFSSAEDAKDAMDSCNNTEIEGRSIRLEFSQ-----------GGGPQGGGRGGSA 499
Query: 614 DS 615
S
Sbjct: 500 QS 501
>GAR2_SCHPO (P41891) Protein gar2
Length = 500
Score = 231 bits (588), Expect = 6e-60
Identities = 193/585 (32%), Positives = 272/585 (45%), Gaps = 103/585 (17%)
Query: 88 KTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDE 147
KTSVK K A S + + E + IAK+ +K V K+ + +SS E
Sbjct: 6 KTSVKKSVKETASKKGAIEKPSKSKKITKEAAKEIAKQSSKTDVSPKKSKKEAKRASSPE 65
Query: 148 DSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAK 207
P+KK+ K KK++ SSSESE + SS E E S+
Sbjct: 66 -----------------PSKKSVKKQ-------KKSKKKEESSSESESESSSSESESSSS 101
Query: 208 QPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDS 267
+ + + E SSS+ SSSESE+E VK SS+S
Sbjct: 102 ESESS-------SSESESSSSESSSSESEEE--------------VIVKTEEKKESSSES 140
Query: 268 DSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPATTT---- 323
SSS+ +++++ A +K EK ESS D SSESS E++S+ +++
Sbjct: 141 SSSSESEEEEE-------------AVVKIEEKKESSSDSSSESSSSESESESSSSESEEE 187
Query: 324 --VAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKV 381
V + + KK SS+S + S SDS + D SDS +S EDEK K
Sbjct: 188 EEVVEKTEEKKEGSSESSSDSESSSDSSSESGDSD-SSSDSESESSSEDEKKRKAEP--- 243
Query: 382 KDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLA 441
AS + A T +Q NE + T+FVG LS++V + F++ G +V R+
Sbjct: 244 -------ASEERPAKITKPSQDSNE-TCTVFVGRLSWNVDDQWLGQEFEEYGTIVGARVI 295
Query: 442 TD-EDGRFKGFGHVEFATAAAAQSALEYNGS-ELLQRPVRLDLARERGAYT-PNSGAANN 498
D + GR KG+G+V+F T AA++A+ NG+ E+ R V LDL+ R A P +
Sbjct: 296 MDGQSGRSKGYGYVDFETPEAAKAAVAANGTKEIDGRMVNLDLSNPRPANPQPYAQQRAG 355
Query: 499 SFQKGGRGQSQTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAY 558
+F S TVFV EDD+ ++ FG CG+I I +P D +SG +KGF Y
Sbjct: 356 NFGDQLSEPSDTVFVGNLSFNATEDDLSTA----FGGCGDIQSIRLPTDPQSGRLKGFGY 411
Query: 559 LDFSDTNSVNKALELHDSDLGGFTLAVDEAKPRDNQGSGGRSGGGRSGGGRGGRFDSGRG 618
+ FSD +S K +E++ + G +D + P R+GGG G GRG
Sbjct: 412 VTFSDIDSAKKCVEMNGHFIAGRPCRLDFSTP--------RTGGGSRG---------GRG 454
Query: 619 GGRGRFGSGGRGGDRGGRGGRGGGGRGG---RGTPLRAEGKKTTF 660
G GR G GGRGG GGRG GG R G RG+ G K TF
Sbjct: 455 GFGGRGGFGGRGGFGGGRGRGRGGARSGNPNRGSVAPFSGNKVTF 499
Score = 164 bits (414), Expect = 9e-40
Identities = 155/527 (29%), Positives = 239/527 (44%), Gaps = 119/527 (22%)
Query: 25 AKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETK--LQKVKKESSSDDDSSSEDEKPAP 82
AKK K + + V++ +A K+ E +K KK TK +++ K+SS D S + +K A
Sbjct: 2 AKKDKTSVKKSVKE--TASKKGAIEKPSKSKKITKEAAKEIAKQSSKTDVSPKKSKKEAK 59
Query: 83 KVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDED 142
+ + + S K+ K K SSS S+ +SS E E + + E SSS+ +
Sbjct: 60 RASSPEPSKKSVKKQKKSKKKEESSSESESESSSSESESSSS--------ESESSSSESE 111
Query: 143 SSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEED 202
SSS E SSSES++E K + SSS S +S EE+
Sbjct: 112 SSSSESSSSESEEE---------------------VIVKTEEKKESSSESSSSSESEEEE 150
Query: 203 EPSAK-QPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAAD 261
E K + KKE + + + ES S+ SSSESE+E+ V+ + K G+++
Sbjct: 151 EAVVKIEEKKESSSDSSSESSSSESESESSSSESEEEEEVVEKTEEK-------KEGSSE 203
Query: 262 SDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPAT 321
S SSDS+SSSD SES D +SS S+ E+ S+
Sbjct: 204 S-SSDSESSSD-------------------------SSSESGDSDSSSDSESESSSEDEK 237
Query: 322 TTVAKPSAVKKSASSDSDDEDSSDSDSE-VKKDKMDVDESDSSEDSDE----------ED 370
A+P++ ++ A +DS+++ + V + +VD+ ++ +E D
Sbjct: 238 KRKAEPASEERPAKITKPSQDSNETCTVFVGRLSWNVDDQWLGQEFEEYGTIVGARVIMD 297
Query: 371 EKSTK----------TPQ----------KKVKDVEMV--DASSGKNAPKTPAAQTE---- 404
+S + TP+ K D MV D S+ + A P AQ
Sbjct: 298 GQSGRSKGYGYVDFETPEAAKAAVAANGTKEIDGRMVNLDLSNPRPANPQPYAQQRAGNF 357
Query: 405 ----NEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATD-EDGRFKGFGHVEFATA 459
+E S T+FVGNLSF+ D+ F CG++ +RL TD + GR KGFG+V F+
Sbjct: 358 GDQLSEPSDTVFVGNLSFNATEDDLSTAFGGCGDIQSIRLPTDPQSGRLKGFGYVTFSDI 417
Query: 460 AAAQSALEYNGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRG 506
+A+ +E NG + RP RLD + TP +G + +GGRG
Sbjct: 418 DSAKKCVEMNGHFIAGRPCRLDFS------TPRTGGGS----RGGRG 454
Score = 92.4 bits (228), Expect = 3e-18
Identities = 79/275 (28%), Positives = 134/275 (48%), Gaps = 33/275 (12%)
Query: 4 SSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSA------KKQKIAEVAAKQKKE 57
S KKS + + P +KK + A E+ KQ S K +K A+ A+ +
Sbjct: 8 SVKKSVKETASKKGAIEKPSKSKKITKEAAKEIAKQSSKTDVSPKKSKKEAKRASSPEPS 67
Query: 58 TKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDE 117
K K +K+S ++SSSE E + + ++ ++ ++ + SSSS+ SS+
Sbjct: 68 KKSVKKQKKSKKKEESSSESESESSS-----SESESSSSESESSSSESESSSSESSSSES 122
Query: 118 EEEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVT 177
EEEVI K K ++SSS+ SSSES++E+ A V + KK + + S
Sbjct: 123 EEEVIVKTEEK------------KESSSESSSSSESEEEEEAV-VKIEEKKESSSDSSSE 169
Query: 178 APAKKAQPAPSSSSESEDDD-----SSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSS 232
+ + +++ + SSSSESE+++ + E+ E S++ + + + + SS DS
Sbjct: 170 SSSSESE-SESSSSESEEEEEVVEKTEEKKEGSSESSSDSESSSDSSSESGDSDSSSDSE 228
Query: 233 SE--SEDEKPAVKVSAPSKVVPAAVKNGAADSDSS 265
SE SEDEK K S+ PA + + DS+ +
Sbjct: 229 SESSSEDEKKR-KAEPASEERPAKITKPSQDSNET 262
Score = 89.7 bits (221), Expect = 2e-17
Identities = 78/248 (31%), Positives = 123/248 (49%), Gaps = 30/248 (12%)
Query: 3 KSSKKSATKVEAAAPVA--------AAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQ 54
K SK EAA +A + KS K+AKRA+ E K+ S KKQK +K+
Sbjct: 25 KPSKSKKITKEAAKEIAKQSSKTDVSPKKSKKEAKRASSPEPSKK-SVKKQK----KSKK 79
Query: 55 KKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKA------KPAPSSS 108
K+E+ + + SSS+ +SSS + + + + +S + + ++ K SS
Sbjct: 80 KEESSSESESESSSSESESSSSESESSSSESESSSSESSSSESEEEVIVKTEEKKESSSE 139
Query: 109 SSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDS-SSDEDSSSESDDEKPAAKVAVPAK 167
SS S+EEEE + K + +K+ESSSD S SS +S SES + + V K
Sbjct: 140 SSSSSESEEEEEAVVK------IEEKKESSSDSSSESSSSESESESSSSESEEEEEVVEK 193
Query: 168 KAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDE-PSAKQPKKEVAVKPAVQKK--KE 224
K GS + + ++ + SSSES D DSS + E S+ + +K+ +PA +++ K
Sbjct: 194 TEEKKEGS-SESSSDSESSSDSSSESGDSDSSSDSESESSSEDEKKRKAEPASEERPAKI 252
Query: 225 ESSSDDSS 232
S DS+
Sbjct: 253 TKPSQDSN 260
Score = 83.2 bits (204), Expect = 2e-15
Identities = 65/214 (30%), Positives = 98/214 (45%), Gaps = 29/214 (13%)
Query: 2 PKSSKKSATKVEAAAPVAAAPKSAKKAKRAAED------------------EVEKQVSAK 43
PK SKK A + + P + K KK+K+ E E E S
Sbjct: 51 PKKSKKEAKRASSPEPSKKSVKKQKKSKKKEESSSESESESSSSESESSSSESESSSSES 110
Query: 44 KQKIAEVAAKQKKETKLQKV--KKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKA 101
+ +E ++ + +E + K KKESSS+ SSSE E+ V ++ ++ + + ++
Sbjct: 111 ESSSSESSSSESEEEVIVKTEEKKESSSESSSSSESEEEEEAVVKIEEKKESSSDSSSES 170
Query: 102 KPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDE-----DSSSESDDE 156
+ S S S S+EEEEV+ K K ESSSD +SSSD DS S SD E
Sbjct: 171 SSSESESESSSSESEEEEEVVEKTEEKK--EGSSESSSDSESSSDSSSESGDSDSSSDSE 228
Query: 157 KPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSS 190
++ + KK A+ S PAK +P+ S+
Sbjct: 229 SESS--SEDEKKRKAEPASEERPAKITKPSQDSN 260
Score = 34.3 bits (77), Expect = 1.1
Identities = 26/112 (23%), Positives = 54/112 (48%), Gaps = 10/112 (8%)
Query: 3 KSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAA--KQKKETKL 60
+ K+S++ + + + + + ++ E+EV ++ KK+ +E ++ + ++
Sbjct: 157 EEKKESSSDSSSESSSSESESESSSSESEEEEEVVEKTEEKKEGSSESSSDSESSSDSSS 216
Query: 61 QKVKKESSSDDDS--SSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSS 110
+ +SSSD +S SSEDEK K + PAK KP+ S+ +
Sbjct: 217 ESGDSDSSSDSESESSSEDEKKR------KAEPASEERPAKITKPSQDSNET 262
>NUCL_CHICK (P15771) Nucleolin (Protein C23)
Length = 694
Score = 211 bits (537), Expect = 5e-54
Identities = 205/696 (29%), Positives = 329/696 (46%), Gaps = 100/696 (14%)
Query: 5 SKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVA--AKQKKETKLQK 62
+KK+AT + AA A K+ AK+A +K V+ +K A V AK K K ++
Sbjct: 58 AKKAATPAKKAA--TPAKKAVTPAKKAVATPAKKAVAPSPKKAAVVGKGAKNGKNAKKEE 115
Query: 63 VKKESSSDDDS---------SSEDEKPAPKVAPLKTSVKNGTT--PAKKAKPAPSSSSSD 111
++E D+D S E+E+PA P+K + K PAKK P+ S+
Sbjct: 116 SEEEDEDDEDDEEDEDEEEESDEEEEPA---VPVKPAAKKSAAAVPAKKPAVVPAKQESE 172
Query: 112 EDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPA 171
E+ +++EE E D++S + ++ + +KP A PAK A A
Sbjct: 173 EEEEEDDEE---------------EDEEDDESEDEAMDTTPAPVKKPTPAKATPAK-AKA 216
Query: 172 KNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQP---KKEVAVKPAVQKKKEESSS 228
++ + + E ED++ SE+++P + P KKE+A K A + KK+++ +
Sbjct: 217 ESEDEEDEEDEDEDEEDEDDEEEDEEESEDEKPVKEAPGKRKKEMANKSAPEAKKKKTET 276
Query: 229 DDSS-----------SESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDK 277
S+ + E+ + A+K K + + + D S ED DK
Sbjct: 277 PASAFSLFVKNLTPTKDYEELRTAIKEFFGKKNLQVSEVRIGSSKRFGYVDFLSAEDMDK 336
Query: 278 KKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSD 337
KKL K+EK++S ES + + +E D A+ VK
Sbjct: 337 ALQLN--GKKLMGLEI--KLEKAKSK--ESLKENKKERD--------ARTLFVKNLPYRV 382
Query: 338 SDDEDSSDSDSEVKKDKMDVDESDSSED-------SDEEDEKSTKTPQKKVKD--VEMVD 388
++DE + ++ ++ ++ +++ SS+ ++ E EK+ + Q D ++D
Sbjct: 383 TEDEMKNVFENALEV-RLVLNKEGSSKGMAYIEFKTEAEAEKALEEKQGTEVDGRAMVID 441
Query: 389 ASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATDEDGRF 448
+ K+ ++ E E SKTL V NLS++ ++ FK + +++ + GR
Sbjct: 442 YTGEKSQQESQKGGGERE-SKTLIVNNLSYAASEETLQELFK---KATSIKMPQNNQGRP 497
Query: 449 KGFGHVEFATAAAAQSALEY-NGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRGQ 507
KG+ VEF TA A+ AL N +E+ R +RL+ + +P+ N + + G Q
Sbjct: 498 KGYAFVEFPTAEDAKEALNSCNNTEIEGRAIRLEFS------SPSWQKGNMNARGGFNQQ 551
Query: 508 SQTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSV 567
S+T+FVRG ED + +L+E F G I+ + D ++G+ KGF ++DFS
Sbjct: 552 SKTLFVRGLS----EDTTEETLRESFE--GSISA-RIVTDRDTGSSKGFGFVDFSSPEDA 604
Query: 568 NKALE-LHDSDLGGFTLAVDEAKPRDNQGSGGRSGGGRSGGGRGGRFDSGRGGGRGRFGS 626
A E + D ++ G + +D AKP+ GG GGG GGRGGR GRGGGRG G
Sbjct: 605 KAAKEAMEDGEIDGNKVTLDFAKPKGEFQRGGGFGGGF--GGRGGR--GGRGGGRG--GF 658
Query: 627 GGRGGDRGGRGGRGGGGRGGR--GTPLRAEGKKTTF 660
GGRGG R G GGRGGG RGGR G + +GKK F
Sbjct: 659 GGRGGGR-GFGGRGGGFRGGRGGGGDHKPQGKKIKF 693
Score = 160 bits (405), Expect = 1e-38
Identities = 159/600 (26%), Positives = 257/600 (42%), Gaps = 95/600 (15%)
Query: 43 KKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAK 102
K K + KQKK K +ES ++ S E+ + P K K TPAKKA
Sbjct: 3 KLAKTPKNQMKQKKMAPPPKKVEESEEEESSDLEESSGEEVMVPPKKQQKAAVTPAKKAA 62
Query: 103 -PAPSSSSSDEDSSDEEEEVIAKKPTKVVVP------------------KKEESSS---- 139
PA +++ + + ++ +A K V P KKEES
Sbjct: 63 TPAKKAATPAKKAVTPAKKAVATPAKKAVAPSPKKAAVVGKGAKNGKNAKKEESEEEDED 122
Query: 140 DEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKK--AQPAPSSSSESEDDD 197
DED DED ESD+E+ + AVP K A AK + PAKK PA S E E++D
Sbjct: 123 DEDDEEDEDEEEESDEEE---EPAVPVKPA-AKKSAAAVPAKKPAVVPAKQESEEEEEED 178
Query: 198 SSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPA-VKVSAPSKVVPAAVK 256
EEDE D+S E+ D PA VK P+K PA K
Sbjct: 179 DEEEDE-----------------------EDDESEDEAMDTTPAPVKKPTPAKATPAKAK 215
Query: 257 NGAAD-SDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEEN 315
+ D D D D +++DD+++ + + P K +K E + S E
Sbjct: 216 AESEDEEDEEDEDEDEEDEDDEEEDEEESEDEKPVKEAPGKRKK------EMANKSAPEA 269
Query: 316 DSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSE-VKKDKMDVDESDSSED--------- 365
K T + S K+ + D E+ + E K + V E
Sbjct: 270 KKKKTETPASAFSLFVKNLTPTKDYEELRTAIKEFFGKKNLQVSEVRIGSSKRFGYVDFL 329
Query: 366 SDEEDEKSTKTPQKKVKDVEM-VDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSD 424
S E+ +K+ + KK+ +E+ ++ + K + K + ++TLFV NL + V +
Sbjct: 330 SAEDMDKALQLNGKKLMGLEIKLEKAKSKESLK---ENKKERDARTLFVKNLPYRVTEDE 386
Query: 425 VENFFKDCGEVVDVRLATDEDGRFKGFGHVEFATAAAAQSAL-EYNGSELLQRPVRLDLA 483
++N F++ ++VRL +++G KG ++EF T A A+ AL E G+E+ R + +D
Sbjct: 387 MKNVFEN---ALEVRLVLNKEGSSKGMAYIEFKTEAEAEKALEEKQGTEVDGRAMVIDYT 443
Query: 484 RERGAYTPNSGAANNSFQKGGRGQSQTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRIS 543
E+ G GG +S+T+ V E+ +LQE F + T I
Sbjct: 444 GEKSQQESQKG--------GGERESKTLIVNNLSYAASEE----TLQELF---KKATSIK 488
Query: 544 VPKDFESGNVKGFAYLDFSDTNSVNKAL-ELHDSDLGGFTLAVDEAKPRDNQGSGGRSGG 602
+P++ G KG+A+++F +AL +++++ G + ++ + P +G+ GG
Sbjct: 489 MPQN-NQGRPKGYAFVEFPTAEDAKEALNSCNNTEIEGRAIRLEFSSPSWQKGNMNARGG 547
>NUCL_MESAU (P08199) Nucleolin (Protein C23)
Length = 713
Score = 203 bits (517), Expect = 1e-51
Identities = 199/703 (28%), Positives = 301/703 (42%), Gaps = 105/703 (14%)
Query: 1 MPKSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKK------QKIAEVAAKQ 54
+P +KK+A A A K+ AK A + AK +K A AK
Sbjct: 72 VPTPAKKAAVTPGKKAAATPAKKAVTPAKAVATPGKKGATQAKALVATPGKKGAVTPAKG 131
Query: 55 KKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDS 114
K K KKE S +D+ +DE SDED
Sbjct: 132 AKNGK--NAKKEDSDEDEDDDDDE-----------------------------DDSDEDE 160
Query: 115 SDEEEE-----VIAKKPTKVVV--PKKEESSSDEDSSSDEDSSSESDD-EKPAAKVAVPA 166
DEEE+ V+ K KV P E+ +ED +E+ E DD E+ A PA
Sbjct: 161 EDEEEDEFEPPVVKGKQGKVAAAAPASEDEDEEEDEEEEEEDEEEEDDSEEEEAMEITPA 220
Query: 167 K--KAPAKNGSVTAP--AKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKK 222
K KAPAK V A A++ + E+D+ EEDE ++ ++E VKPA K+
Sbjct: 221 KGKKAPAKVVPVKAKNVAEEDDDDEEEDEDEEEDEEEEEDEEEEEEEEEEEPVKPAPGKR 280
Query: 223 KEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSS-SDEDDDKKKPA 281
K+E + E++ +K V P + G + + S ++ + + K
Sbjct: 281 KKEMTKQKEVPEAKKQK----VEGSESTTPFNLFIGNLNPNKSVAELKVAISEPFAKNDL 336
Query: 282 TKVAKKLPAAAPIKKVEKSESSDDESSES-------SDEENDSKPATTTVAKPSAVKKSA 334
V + V+ + D E + +E KP K A +
Sbjct: 337 AVVDVRTGTNRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGRDSKKVRAARTLL 396
Query: 335 SSDSDDEDSSDSDSEVKKDKMD---VDESDSSED-------SDEEDEKSTKTPQKKVKDV 384
+ + + D EV +D ++ V + S+ S+ + EK+ + Q D
Sbjct: 397 AKNLSFNITEDELKEVFEDALEIRLVSQDGKSKGIAYIEFKSEADAEKNLEEKQGAEIDG 456
Query: 385 EMVD----ASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRL 440
V G+ +T T + SKTL + NLS+S ++ F+ + +++
Sbjct: 457 RSVSLYYTGEKGQRQERTGKNSTWSGESKTLVLSNLSYSATEETLQEVFE---KATFIKV 513
Query: 441 ATDEDGRFKGFGHVEFATAAAAQSALEY-NGSELLQRPVRLDLARERGAYTPNSGAANNS 499
++ G+ KG+ +EFA+ A+ AL N E+ R +RL+L RG+ PN+ +
Sbjct: 514 PQNQQGKSKGYAFIEFASFEDAKEALNSCNKMEIEGRTIRLELQGPRGS--PNARSQ--- 568
Query: 500 FQKGGRGQSQTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYL 559
S+T+FV+G + E+ +K S + GS R + D E+G+ KGF ++
Sbjct: 569 -------PSKTLFVKGLSEDTTEETLKESFE---GS----VRARIVTDRETGSSKGFGFV 614
Query: 560 DFSDTNSVNKALE-LHDSDLGGFTLAVDEAKPRDNQGSGGRSGGGRSGGGRGGRFDSGRG 618
DF+ A E + D ++ G + +D AKP+ G GGR GG GGRGG GRG
Sbjct: 615 DFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGG----GRG 670
Query: 619 GGRGRFGSGGRGGDRGGRGG-RGGGGRGGRGTPLRAEGKKTTF 660
GGRG FG GRGG GGRGG RGG G GG G + +GKKT F
Sbjct: 671 GGRGGFGGRGRGG-FGGRGGFRGGRGGGGGGGDFKPQGKKTKF 712
Score = 132 bits (333), Expect = 2e-30
Identities = 126/479 (26%), Positives = 204/479 (42%), Gaps = 89/479 (18%)
Query: 132 PKKEES-SSDEDSSSDEDSSSESDDEKPAAK----VAVPAKK------------APAKNG 174
PK+ E S DE+ S +ED SS + P K A PAKK PAK
Sbjct: 20 PKEVEEDSEDEEMSEEEDDSSGEEVVIPQKKGKKATATPAKKVVVSQTKKVAVPTPAKKA 79
Query: 175 SVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQ-------PKKEVAVKPAVQKKKEESS 227
+VT P KKA P+ + + + + A Q P K+ AV PA K +++
Sbjct: 80 AVT-PGKKAAATPAKKAVTPAKAVATPGKKGATQAKALVATPGKKGAVTPAKGAKNGKNA 138
Query: 228 SDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAK- 286
+ S E ED+ D D SD D +E+D+ + P K +
Sbjct: 139 KKEDSDEDEDDDD--------------------DEDDSDEDEEDEEEDEFEPPVVKGKQG 178
Query: 287 KLPAAAPIKKVEKSESSDDESSESSDEENDSK--------PATTTVAKPSAVKKSASSDS 338
K+ AAAP + E E ++E E +EE+DS+ PA A V A + +
Sbjct: 179 KVAAAAPASEDEDEEEDEEEEEEDEEEEDDSEEEEAMEITPAKGKKAPAKVVPVKAKNVA 238
Query: 339 DDEDSSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKT 398
+++D + + E +++ + +E + E+ +EE+E P K+ K EM A K
Sbjct: 239 EEDDDDEEEDEDEEEDEEEEEDEEEEEEEEEEEPVKPAPGKRKK--EMTKQKEVPEAKKQ 296
Query: 399 PAAQTENEGSKTLFVGNLSFSVQRSDV-----ENFFKDCGEVVDVRLATDEDGRFKGFGH 453
+E+ LF+GNL+ + +++ E F K+ VVDVR T+ + FG+
Sbjct: 297 KVEGSESTTPFNLFIGNLNPNKSVAELKVAISEPFAKNDLAVVDVRTGTN-----RKFGY 351
Query: 454 VEFATAAAAQSALEYNGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRGQSQTVFV 513
V+F +A + ALE G ++ ++L+ + R + + ++T+
Sbjct: 352 VDFESAEDLEKALELTGLKVFGNEIKLEKPKGRDSKKVRA--------------ARTLLA 397
Query: 514 RGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVNKALE 572
+ ED++K E F EI +S + G KG AY++F K LE
Sbjct: 398 KNLSFNITEDELK----EVFEDALEIRLVS-----QDGKSKGIAYIEFKSEADAEKNLE 447
Score = 129 bits (323), Expect = 3e-29
Identities = 145/581 (24%), Positives = 249/581 (41%), Gaps = 106/581 (18%)
Query: 92 KNGTTPAKKAKPAPSSSSSDEDSSDEE----------EEVI-----AKKPT-----KVVV 131
K G T + K AP +EDS DEE EEV+ KK T KVVV
Sbjct: 5 KAGKTHGEAKKMAPPPKEVEEDSEDEEMSEEEDDSSGEEVVIPQKKGKKATATPAKKVVV 64
Query: 132 PKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAK--KAPAKNGS------VTAPAKKA 183
+ ++ + + + + PA K PAK P K G+ V P KK
Sbjct: 65 SQTKKVAVPTPAKKAAVTPGKKAAATPAKKAVTPAKAVATPGKKGATQAKALVATPGKKG 124
Query: 184 QPAPS------------SSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKK-------- 223
P+ S E EDDD E+D ++ ++E +P V K K
Sbjct: 125 AVTPAKGAKNGKNAKKEDSDEDEDDDDDEDDSDEDEEDEEEDEFEPPVVKGKQGKVAAAA 184
Query: 224 ----EESSSDDSSSESEDEK--------------PAVKVSAPSKVVPAAVKNGAADSDSS 265
+E +D E EDE+ PA AP+KVVP KN A + D
Sbjct: 185 PASEDEDEEEDEEEEEEDEEEEDDSEEEEAMEITPAKGKKAPAKVVPVKAKNVAEEDDDD 244
Query: 266 DSDSSSDEDDDKKKPATKVAKKLPAAAPIK----KVEKSESSDDESSESSDEENDSKPAT 321
+ + +E+D++++ + ++ P+K K +K + E E+ ++ + +T
Sbjct: 245 EEEDEDEEEDEEEEEDEEEEEEEEEEEPVKPAPGKRKKEMTKQKEVPEAKKQKVEGSEST 304
Query: 322 TTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSE--------DSDEEDEKS 373
T + + + + S+ K D VD + +S E+ EK+
Sbjct: 305 TPF-NLFIGNLNPNKSVAELKVAISEPFAKNDLAVVDVRTGTNRKFGYVDFESAEDLEKA 363
Query: 374 TKTPQKKVKDVEM-VDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDVENFFKDC 432
+ KV E+ ++ G+++ K AA +TL NLSF++ +++ F+D
Sbjct: 364 LELTGLKVFGNEIKLEKPKGRDSKKVRAA-------RTLLAKNLSFNITEDELKEVFED- 415
Query: 433 GEVVDVRLATDEDGRFKGFGHVEFATAAAAQSAL-EYNGSELLQRPVRLDLARERGAYTP 491
+++RL + +DG+ KG ++EF + A A+ L E G+E+ R V L E+G
Sbjct: 416 --ALEIRLVS-QDGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGRSVSLYYTGEKGQRQE 472
Query: 492 NSGAANNSFQKGGRGQSQTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFESG 551
+G N+++ G+S+T+ + E+ +LQE F + T I VP++ + G
Sbjct: 473 RTG-KNSTWS----GESKTLVLSNLSYSATEE----TLQEVF---EKATFIKVPQN-QQG 519
Query: 552 NVKGFAYLDFSDTNSVNKAL-ELHDSDLGGFTLAVDEAKPR 591
KG+A+++F+ +AL + ++ G T+ ++ PR
Sbjct: 520 KSKGYAFIEFASFEDAKEALNSCNKMEIEGRTIRLELQGPR 560
>NUCL_RAT (P13383) Nucleolin (Protein C23)
Length = 712
Score = 195 bits (496), Expect = 3e-49
Identities = 192/697 (27%), Positives = 298/697 (42%), Gaps = 95/697 (13%)
Query: 1 MPKSSKKSAT---KVEAAAPVAAAPKSAKKA-----KRAAEDEVEKQVSAKKQKI--AEV 50
+P +KK+A K AA P A AK K AA+ + KK + A+
Sbjct: 73 VPTPAKKAAVTPGKKAAATPAKKAVTPAKVVPTPGKKGAAQAKALVPTPGKKGAVTPAKG 132
Query: 51 AAKQKKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSS 110
A K K + E D+D S EDE + P V G PAK A AP+S
Sbjct: 133 AKNGKNAKKEDSDEDEDEEDEDDSDEDEDEEDEFEP---PVVKGVKPAKAAPAAPASEDE 189
Query: 111 DEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAP 170
DE+ D+E++ DE+ ++DS E + PA PAK P
Sbjct: 190 DEEDDDDEDD----------------DDDDEEEEEEDDSEEEVMEITPAKGKKTPAKVVP 233
Query: 171 AKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDD 230
K SV ++ E ++D+ EED+ + ++E VK A K+K+E +
Sbjct: 234 VKAKSVAE--EEEDDEDDEDEEEDEDEEDEEDDEDEDEEEEEEPVKAAPGKRKKEMTKQK 291
Query: 231 SSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPA 290
+ E++ +K ++ S P+ + N + ++ + E K A V +
Sbjct: 292 EAPEAKKQK--IEGSEPTTPFNLFIGNLNPNKSVAELKVAISELFAKNDLAA-VDVRTGT 348
Query: 291 AAPIKKVEKSESSDDESSES-------SDEENDSKPATTTVAKPSAVKKSASSDSDDEDS 343
V+ + D E + +E KP K A + + + +
Sbjct: 349 NRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGRDSKKVRAARTLLAKNLSFNIT 408
Query: 344 SDSDSEVKKDKMD---VDESDSSED-------SDEEDEKSTKTPQKKVKDVEMVD----A 389
D EV +D ++ V + S+ S+ + EK+ + Q D V
Sbjct: 409 EDELKEVFEDAVEIRLVSQDGRSKGIAYIEFKSEADAEKNLEEKQGAEIDGRSVSLYYTG 468
Query: 390 SSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATDEDGRFK 449
G+ +T T + SKTL + NLS+S ++ F+ + +++ + G+ K
Sbjct: 469 EKGQRQERTGKNSTWSGESKTLVLSNLSYSATEETLQEVFE---KATFIKVPQNPHGKSK 525
Query: 450 GFGHVEFATAAAAQSALEY-NGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRGQS 508
G+ +EFA+ A+ AL N E+ R +RL+L RG+ PN+ + S
Sbjct: 526 GYAFIEFASFEDAKEALNSCNKMEIEGRTIRLELQGPRGS--PNARSQ----------PS 573
Query: 509 QTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVN 568
+T+FV+G + E+ +K S + GS R + D E+G+ KGF ++DF+
Sbjct: 574 KTLFVKGLSEDTTEETLKESFE---GS----VRARIVTDRETGSSKGFGFVDFNSEEDAK 626
Query: 569 KALE-LHDSDLGGFTLAVDEAKPRDNQGSGGRSGG----GRSGGGRGGRFDSGRGGGRGR 623
A E + D ++ G + +D AKP+ G GGR GG G GGGRGGR G GGRGR
Sbjct: 627 AAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGR---GGFGGRGR 683
Query: 624 FGSGGRGGDRGGRGGRGGGGRGGRGTPLRAEGKKTTF 660
G GGRGG RGGRGG G + +GKKT F
Sbjct: 684 GGFGGRGGFRGGRGG---------GGDFKPQGKKTKF 711
Score = 144 bits (364), Expect = 6e-34
Identities = 139/531 (26%), Positives = 214/531 (40%), Gaps = 107/531 (20%)
Query: 52 AKQKKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKK-----AKPAPS 106
A KE + +E S D+D SS +E+ V P K K TTPAKK K A
Sbjct: 17 APPPKEVEEDSEDEEMSEDEDDSSGEEEV---VIPQKKGKKATTTPAKKVVVSQTKKAAV 73
Query: 107 SSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPA 166
+ + + + ++ A K V P K + + ++ AK VP
Sbjct: 74 PTPAKKAAVTPGKKAAATPAKKAVTPAKVVPTPGKKGAAQ-------------AKALVP- 119
Query: 167 KKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEES 226
P K G+VT PAK A+ ++ E D+D EEDE +
Sbjct: 120 --TPGKKGAVT-PAKGAKNGKNAKKEDSDEDEDEEDE---------------------DD 155
Query: 227 SSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAK 286
S +D E E E P VK P+K PAA + D D D D D+DDD+++
Sbjct: 156 SDEDEDEEDEFEPPVVKGVKPAKAAPAA--PASEDEDEEDDDDEDDDDDDEEE------- 206
Query: 287 KLPAAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDS 346
E+ + S++E E + + PA K +V + D DDED +
Sbjct: 207 -----------EEEDDSEEEVMEITPAKGKKTPAKVVPVKAKSVAEEEEDDEDDEDEEED 255
Query: 347 DSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENE 406
+ E + +E D ED +EE+E P K+ K EM A K +E
Sbjct: 256 EDE------EDEEDDEDEDEEEEEEPVKAAPGKRKK--EMTKQKEAPEAKKQKIEGSEPT 307
Query: 407 GSKTLFVGNLSFSVQRSDV-----ENFFKDCGEVVDVRLATDEDGRFKGFGHVEFATAAA 461
LF+GNL+ + +++ E F K+ VDVR T+ + FG+V+F +A
Sbjct: 308 TPFNLFIGNLNPNKSVAELKVAISELFAKNDLAAVDVRTGTN-----RKFGYVDFESAED 362
Query: 462 AQSALEYNGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRGQSQTVFVRGFDKFQG 521
+ ALE G ++ ++L+ + R + + ++T+ +
Sbjct: 363 LEKALELTGLKVFGNEIKLEKPKGRDSKKVRA--------------ARTLLAKNLSFNIT 408
Query: 522 EDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVNKALE 572
ED++K E F EI +S + G KG AY++F K LE
Sbjct: 409 EDELK----EVFEDAVEIRLVS-----QDGRSKGIAYIEFKSEADAEKNLE 450
>NUCL_MOUSE (P09405) Nucleolin (Protein C23)
Length = 706
Score = 189 bits (479), Expect = 3e-47
Identities = 184/687 (26%), Positives = 290/687 (41%), Gaps = 111/687 (16%)
Query: 1 MPKSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKL 60
+P KK A + +A P +A AK A + +AKK+ E +
Sbjct: 103 IPTPGKKGAAQAKALVPTPGKKGAATPAKGAKNGK-----NAKKE--------DSDEDED 149
Query: 61 QKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEE 120
++ + +S D+D EDE P V G PAK A AP+S ++D +++EE
Sbjct: 150 EEDEDDSDEDEDDEEEDEFEPPIV--------KGVKPAKAAPAAPASEDEEDDEDEDDEE 201
Query: 121 VIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPA 180
D+D ++DS E + A PAK P K SV A
Sbjct: 202 -------------------DDDEEEEDDSEEEVMEITTAKGKKTPAKVVPMKAKSV---A 239
Query: 181 KKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKP 240
++ + ++DD E+DE ++ ++E VK A K+K+E + + E++ +K
Sbjct: 240 EEEDDEEEDEDDEDEDDEEEDDEDDDEEEEEEEPVKAAPGKRKKEMTKQKEAPEAKKQK- 298
Query: 241 AVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKS 300
V+ S P+ + N + ++ + E K A V + V+
Sbjct: 299 -VEGSEPTTPFNLFIGNLNPNKSVNELKFAISELFAKNDLAV-VDVRTGTNRKFGYVDFE 356
Query: 301 ESSDDESSES-------SDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKD 353
+ D E + +E KP K A + + + + D EV +D
Sbjct: 357 SAEDLEKALELTGLKVFGNEIKLEKPKGRDSKKVRAARTLLAKNLSFNITEDELKEVFED 416
Query: 354 KMD---VDESDSSED-------SDEEDEKSTKTPQKKVKDVEMVD----ASSGKNAPKTP 399
M+ V + S+ S+ + EK+ + Q D V G+ +T
Sbjct: 417 AMEIRLVSQDGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGRSVSLYYTGEKGQRQERTG 476
Query: 400 AAQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATDEDGRFKGFGHVEFATA 459
T + SKTL + NLS+S + +E F+ + +++ + G+ KG+ +EFA+
Sbjct: 477 KTSTWSGESKTLVLSNLSYSATKETLEEVFE---KATFIKVPQNPHGKPKGYAFIEFASF 533
Query: 460 AAAQSALEY-NGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRGQSQTVFVRGFDK 518
A+ AL N E+ R +RL+L P S+T+FV+G +
Sbjct: 534 EDAKEALNSCNKMEIEGRTIRLELQGSNSRSQP----------------SKTLFVKGLSE 577
Query: 519 FQGEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVNKALE-LHDSD 577
E+ +K S + GS R + D E+G+ KGF ++DF+ A E + D +
Sbjct: 578 DTTEETLKESFE---GS----VRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGE 630
Query: 578 LGGFTLAVDEAKPRDNQGSGGRSGG----GRSGGGRGGRFDSGRGGGRGRFGSGGRGGDR 633
+ G + +D AKP+ G GGR GG G GGGRGGR G GGRGR G GGRGG R
Sbjct: 631 IDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGR---GGFGGRGRGGFGGRGGFR 687
Query: 634 GGRGGRGGGGRGGRGTPLRAEGKKTTF 660
GGRGG G + +GKKT F
Sbjct: 688 GGRGG---------GGDFKPQGKKTKF 705
Score = 134 bits (338), Expect = 6e-31
Identities = 131/504 (25%), Positives = 207/504 (40%), Gaps = 83/504 (16%)
Query: 92 KNGTTPAKKAKPAPSSSSSDEDSSDEE---EEVIAKKPTKVVVPKKEESSSDEDSSSDED 148
K G T + K AP +EDS DEE +E + +VV+P+K+ + +
Sbjct: 5 KAGKTHGEAKKMAPPPKEVEEDSEDEEMSEDEDDSSGEEEVVIPQKKGKKATTTPAKKVV 64
Query: 149 SSSESDDEKPAAKVAVPAKKAPAKNG--SVTAPAKKAQPAPSSSSESEDDDSSEEDEPSA 206
S + A V PAKKA G +V PAKK P+ + + + +
Sbjct: 65 VS-----QTKKAAVPTPAKKAAVTPGKKAVATPAKK-NITPAKVIPTPGKKGAAQAKALV 118
Query: 207 KQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSD 266
P K+ A PA K +++ + S E EDE+ D D SD
Sbjct: 119 PTPGKKGAATPAKGAKNGKNAKKEDSDEDEDEE---------------------DEDDSD 157
Query: 267 SDSSSDEDDDKKKP---ATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPA--- 320
D +E+D+ + P K AK PAA + E E DDE + +EE+DS+
Sbjct: 158 EDEDDEEEDEFEPPIVKGVKPAKAAPAAPASEDEEDDEDEDDEEDDDEEEEDDSEEEVME 217
Query: 321 -TTTVAKPSAVK------KSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSDEEDEKS 373
TT K + K KS + + DDE+ + D + D +E D +D +EE+E+
Sbjct: 218 ITTAKGKKTPAKVVPMKAKSVAEEEDDEEEDEDDEDE-----DDEEEDDEDDDEEEEEEE 272
Query: 374 TKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDV-----ENF 428
+ EM A K +E LF+GNL+ + +++ E F
Sbjct: 273 PVKAAPGKRKKEMTKQKEAPEAKKQKVEGSEPTTPFNLFIGNLNPNKSVNELKFAISELF 332
Query: 429 FKDCGEVVDVRLATDEDGRFKGFGHVEFATAAAAQSALEYNGSELLQRPVRLDLARERGA 488
K+ VVDVR T+ + FG+V+F +A + ALE G ++ ++L+ + R +
Sbjct: 333 AKNDLAVVDVRTGTN-----RKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGRDS 387
Query: 489 YTPNSGAANNSFQKGGRGQSQTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDF 548
+ ++T+ + ED++K E F EI +S
Sbjct: 388 KKVRA--------------ARTLLAKNLSFNITEDELK----EVFEDAMEIRLVS----- 424
Query: 549 ESGNVKGFAYLDFSDTNSVNKALE 572
+ G KG AY++F K LE
Sbjct: 425 QDGKSKGIAYIEFKSEADAEKNLE 448
>NUCL_HUMAN (P19338) Nucleolin (Protein C23)
Length = 706
Score = 184 bits (467), Expect = 6e-46
Identities = 190/702 (27%), Positives = 301/702 (42%), Gaps = 113/702 (16%)
Query: 26 KKAKRAAEDEVEKQVSAKKQKIAEVAAKQK------KETKLQKVKKESSSDDDSSSEDEK 79
KK K+AA +K V + +K+A +K K+ KK + ++ +K
Sbjct: 50 KKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKK 109
Query: 80 PA-PKVAPLKTSVKNGTT-PAKKAKPAPSSSSSD-------------EDSSDEEEEVIAK 124
A P A + T K G PAK AK ++ D ED DE+E+
Sbjct: 110 GATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEI 169
Query: 125 KPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKP-AAKVAVPAKKAPAKNGSVTAPAKKA 183
+P + +S DED DED + DDE+ + + A+ A K + P K
Sbjct: 170 EPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAK 229
Query: 184 QPAPSSSSESEDDDSSE-----------EDEPSAKQPKKEVAVKPAVQKKKEESSSDDSS 232
A E +D+D + ED+ ++ ++E VK A K+K+E + ++
Sbjct: 230 NVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAA 289
Query: 233 SESEDEKPAVKVSAPSKVVPAAVKN-----GAADSDSSDSDSSSDED---DDKKKPATKV 284
E++ +K V+ + P+ V N A + + SD + D D + T+
Sbjct: 290 PEAKKQK--VEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRK 347
Query: 285 --------AKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVK----- 331
A+ L A + ++ + + + A T +AK K
Sbjct: 348 FGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDE 407
Query: 332 -KSASSDSDDEDSSDSDSEVK-------KDKMDVDESDSSEDSDEEDEKSTKTPQKKVKD 383
K D+ + D + K K + D +++ + E D +S K
Sbjct: 408 LKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKG 467
Query: 384 VEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATD 443
D GKN+ T + SKTL + NLS+S ++ F+ + +++ +
Sbjct: 468 QNQ-DYRGGKNS-------TWSGESKTLVLSNLSYSATEETLQEVFE---KATFIKVPQN 516
Query: 444 EDGRFKGFGHVEFATAAAAQSALEY-NGSELLQRPVRLDLARERGAYTPNSGAANNSFQK 502
++G+ KG+ +EFA+ A+ AL N E+ R +RL+L RG+ PN+ +
Sbjct: 517 QNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGS--PNARSQ------ 568
Query: 503 GGRGQSQTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFS 562
S+T+FV+G ED + +L+E F R + D E+G+ KGF ++DF+
Sbjct: 569 ----PSKTLFVKGLS----EDTTEETLKESFDGS---VRARIVTDRETGSSKGFGFVDFN 617
Query: 563 DTNSVNKALELHDSDLGGFTLAVDEAKPRDNQGSGGRSGG----GRSGGGRGGRFDSGRG 618
+A+E D ++ G + +D AKP+ G GGR GG G GGGRGGR G
Sbjct: 618 SEEDAKEAME--DGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGR---GGF 672
Query: 619 GGRGRFGSGGRGGDRGGRGGRGGGGRGGRGTPLRAEGKKTTF 660
GGRGR G GGRGG RGGRGG GG P +GKKT F
Sbjct: 673 GGRGRGGFGGRGGFRGGRGG------GGDHKP---QGKKTKF 705
Score = 145 bits (367), Expect = 3e-34
Identities = 140/540 (25%), Positives = 227/540 (41%), Gaps = 89/540 (16%)
Query: 92 KNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSS 151
KN P K A P ED E+E +VV+P+K+ + S+ S
Sbjct: 8 KNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVS- 66
Query: 152 ESDDEKPAAKVAV--PAKKA---PAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSA 206
P KVAV PAKKA P K + T PAKK P+ + + + +
Sbjct: 67 ------PTKKVAVATPAKKAAVTPGKKAAAT-PAKKTV-TPAKAVTTPGKKGATPGKALV 118
Query: 207 KQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSD 266
P K+ A PA K +++ + S E ED+ + +
Sbjct: 119 ATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDD---------------------SEEDEE 157
Query: 267 SDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPAT--TTV 324
D DED+D+ +PA A K AAAP + E E +D+ + DEE+DS+ TT
Sbjct: 158 DDEDEDEDEDEIEPA---AMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTP 214
Query: 325 AK--------PSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTK- 375
AK P K A + ++ED D D + +D D D+ D E+ +EE+E+ K
Sbjct: 215 AKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 274
Query: 376 TPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDVEN-----FFK 430
P K+ K EM + A K TE + LFVGNL+F+ +++ F K
Sbjct: 275 APGKRKK--EMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAK 332
Query: 431 DCGEVVDVRLATDEDGRFKGFGHVEFATAAAAQSALEYNGSELLQRPVRLDLARERGAYT 490
+ VVDVR+ G + FG+V+F +A + ALE G ++ ++L+ + + +
Sbjct: 333 NDLAVVDVRI-----GMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGKDSKK 387
Query: 491 PNSGAANNSFQKGGRGQSQTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFES 550
++T+ + +D++K E F EI +S +
Sbjct: 388 ER--------------DARTLLAKNLPYKVTQDELK----EVFEDAAEIRLVS-----KD 424
Query: 551 GNVKGFAYLDFSDTNSVNKAL-ELHDSDLGGFTLAV----DEAKPRDNQGSGGRSGGGRS 605
G KG AY++F K E +++ G ++++ ++ + +D +G + G S
Sbjct: 425 GKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGES 484
Score = 145 bits (366), Expect = 3e-34
Identities = 175/740 (23%), Positives = 278/740 (36%), Gaps = 198/740 (26%)
Query: 23 KSAKKAKRAAEDEVEKQVSAKKQKIA---EVAAKQKKETKLQKVKKESSSDDDSSSEDEK 79
K A K ED ++++S ++ + EV QKK K ++ +
Sbjct: 15 KMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKK--------AAATSAKKVVVS 66
Query: 80 PAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVV-------- 131
P KVA + K TP KKA P+ + + P K +V
Sbjct: 67 PTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGA 126
Query: 132 ------------PKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAP 179
KKE+S +ED S+ED + D+++ ++ A KA
Sbjct: 127 AIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKA---------- 176
Query: 180 AKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEK 239
A AP+S E ++DD +ED+ ++ DDS E+ +
Sbjct: 177 ---AAAAPASEDEDDEDDEDDEDD--------------------DDDEEDDSEEEAMETT 213
Query: 240 PAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEK 299
PA K +KVVP KN A D D + D D+DDD+ E
Sbjct: 214 PA-KGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDD------------------ED 254
Query: 300 SESSDDESSESSDEENDSKPATTTVAKPSAVKKSA------------------------- 334
+ DDE E +EE K A K A +K+A
Sbjct: 255 DDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLN 314
Query: 335 -SSDSDDEDSSDSDSEVKKDKMDVDESDSSE--------DSDEEDEKSTKTPQKKVKDVE 385
+ + + + SD K D VD +S E+ EK+ + KV E
Sbjct: 315 FNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNE 374
Query: 386 M-VDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATDE 444
+ ++ GK++ K ++TL NL + V + +++ F+D E +RL + +
Sbjct: 375 IKLEKPKGKDSKK-------ERDARTLLAKNLPYKVTQDELKEVFEDAAE---IRLVS-K 423
Query: 445 DGRFKGFGHVEFATAAAAQSAL-EYNGSELLQRPVRLDLARERGAYTPNSGAANNSFQKG 503
DG+ KG ++EF T A A+ E G+E+ R + L E+G G N+++
Sbjct: 424 DGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWS-- 481
Query: 504 GRGQSQTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSD 563
G+S+T+ + E+ +LQE F + T I VP++ ++G KG+A+++F+
Sbjct: 482 --GESKTLVLSNLSYSATEE----TLQEVF---EKATFIKVPQN-QNGKSKGYAFIEFAS 531
Query: 564 TNSVNKAL-ELHDSDLGGFTLAVDEAKPRDNQGSGG------------------------ 598
+AL + ++ G + ++ PR + +
Sbjct: 532 FEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESF 591
Query: 599 -----------RSGGGRSGGG--------------RGGRFDSGR-----GGGRGRFGSGG 628
R G G G G D + +G G GG
Sbjct: 592 DGSVRARIVTDRETGSSKGFGFVDFNSEEDAKEAMEDGEIDGNKVTLDWAKPKGEGGFGG 651
Query: 629 RGGDRGGRGGRGGGGRGGRG 648
RGG RGG GGR GGGRGGRG
Sbjct: 652 RGGGRGGFGGR-GGGRGGRG 670
>NSR1_YEAST (P27476) Nuclear localization sequence binding protein
(P67)
Length = 414
Score = 181 bits (458), Expect = 7e-45
Identities = 153/467 (32%), Positives = 217/467 (45%), Gaps = 73/467 (15%)
Query: 199 SEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNG 258
++++ ++KQ K+E A K E SSS SSSESE E + S+ S
Sbjct: 10 NKKEVKASKQAKEEKA-KAVSSSSSESSSSSSSSSESESESESESESSSS---------- 58
Query: 259 AADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSK 318
S SSDS+SSS D + + A KK E +SS S SSDEE + +
Sbjct: 59 ---SSSSDSESSSSSSSDSE-----------SEAETKKEESKDSSSSSSDSSSDEEEEEE 104
Query: 319 PATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDS-DEEDEKSTKTP 377
T K K+S+SSDS SSDS+SE ++ D+ SED+ +EEDE+S+
Sbjct: 105 KEET---KKEESKESSSSDSSSSSSSDSESEKEESN---DKKRKSEDAEEEEDEESSNKK 158
Query: 378 QKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVD 437
QK E E T+FVG LS+S+ ++ F+ G V+
Sbjct: 159 QK----------------------NEETEEPATIFVGRLSWSIDDEWLKKEFEHIGGVIG 196
Query: 438 VRLATDE-DGRFKGFGHVEFATAAAAQSAL-EYNGSELLQRPVRLDLARERGAYTPNSGA 495
R+ + R +G+G+V+F + A+ A+ E G E+ RP+ D++ + A +
Sbjct: 197 ARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSKPA---GNND 253
Query: 496 ANNSFQKGGRGQSQTVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKG 555
F S T+F+ G F + D ++ E F GE+ + +P E+ KG
Sbjct: 254 RAKKFGDTPSEPSDTLFL-GNLSFNADRD---AIFELFAKHGEVVSVRIPTHPETEQPKG 309
Query: 556 FAYLDFSDTNSVNKALE-LHDSDLGGFTLAVDEAKPRDNQGSGGRSGGGRSGGGRGGRFD 614
F Y+ FS+ KAL+ L + + +D + PR N GGR GG R GGRGG
Sbjct: 310 FGYVQFSNMEDAKKALDALQGEYIDNRPVRLDFSSPRPN-NDGGR-GGSRGFGGRGG--- 364
Query: 615 SGRGGGRGRFGSGGRGGDRGGRGGRGGGGRGGRGTPLRAEGKKTTFA 661
GRGG R G GGRGG RGGRGG G G PL +FA
Sbjct: 365 -GRGGNR---GFGGRGGARGGRGGFRPSGSGANTAPLGRSRNTASFA 407
Score = 123 bits (309), Expect = 1e-27
Identities = 126/403 (31%), Positives = 175/403 (43%), Gaps = 64/403 (15%)
Query: 118 EEEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVT 177
++EV A K K K SSS E SSS SSSES+ E
Sbjct: 11 KKEVKASKQAKEEKAKAVSSSSSE-SSSSSSSSSESESE--------------------- 48
Query: 178 APAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESED 237
+ ++ + SSSS+SE SS D S + KKE + K SSS DSSS+ E+
Sbjct: 49 SESESESSSSSSSSDSESSSSSSSDSESEAETKKE-------ESKDSSSSSSDSSSDEEE 101
Query: 238 EKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKV 297
E+ + K + +S SSDS SSS D + +K + K +K
Sbjct: 102 EEEKEETK----------KEESKESSSSDSSSSSSSDSESEKEESNDKK--------RKS 143
Query: 298 EKSESSDDESSESSDEEND--SKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKM 355
E +E +DE S + ++N+ +PAT V + S + E +
Sbjct: 144 EDAEEEEDEESSNKKQKNEETEEPATIFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYER 203
Query: 356 DVDESDSSEDSDEED----EKSTKTPQKKVKDVEMV--DASSGKNAPKTPAAQ----TEN 405
D S D E+ EK+ + Q K D + D S+ K A A+ T +
Sbjct: 204 GTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSKPAGNNDRAKKFGDTPS 263
Query: 406 EGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLAT-DEDGRFKGFGHVEFATAAAAQS 464
E S TLF+GNLSF+ R + F GEVV VR+ T E + KGFG+V+F+ A+
Sbjct: 264 EPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKK 323
Query: 465 ALE-YNGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRG 506
AL+ G + RPVRLD + R N G S GGRG
Sbjct: 324 ALDALQGEYIDNRPVRLDFSSPR---PNNDGGRGGSRGFGGRG 363
Score = 73.2 bits (178), Expect = 2e-12
Identities = 64/207 (30%), Positives = 90/207 (42%), Gaps = 44/207 (21%)
Query: 38 KQVSAKKQKIAEVAAKQKKETKLQKV---KKESSSDDDSSSEDEKPAPKVAPLKTSVKNG 94
K K K A+KQ KE K + V ESSS SSSE E ++ ++
Sbjct: 3 KTTKVKGNKKEVKASKQAKEEKAKAVSSSSSESSSSSSSSSESES--------ESESESE 54
Query: 95 TTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESD 154
++ + + + SSSSS DS E E KKEES SSSD S E +
Sbjct: 55 SSSSSSSSDSESSSSSSSDSESEAE------------TKKEESKDSSSSSSDSSSDEEEE 102
Query: 155 DEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVA 214
+EK KK +K S + SSS S D SE++E + K+ K E A
Sbjct: 103 EEKE------ETKKEESKESS----------SSDSSSSSSSDSESEKEESNDKKRKSEDA 146
Query: 215 VKPAVQKKKEESSSDDSSSESEDEKPA 241
+++++E SS+ E E+PA
Sbjct: 147 -----EEEEDEESSNKKQKNEETEEPA 168
Score = 67.8 bits (164), Expect = 9e-11
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 39/196 (19%)
Query: 23 KSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPAP 82
K K +K+A E++ + S+ + + ++ + E++ + + SSS S SE +
Sbjct: 12 KEVKASKQAKEEKAKAVSSSSSESSSSSSSSSESESESESESESSSSSSSSDSESSSSS- 70
Query: 83 KVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDED 142
+S KK + SSSSS + SSDEEEE K+ TK KEES E
Sbjct: 71 ------SSDSESEAETKKEESKDSSSSSSDSSSDEEEEE-EKEETK-----KEESK--ES 116
Query: 143 SSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEED 202
SSSD SSS SD E + + + +SED + E++
Sbjct: 117 SSSDSSSSSSSDSE------------------------SEKEESNDKKRKSEDAEEEEDE 152
Query: 203 EPSAKQPKKEVAVKPA 218
E S K+ K E +PA
Sbjct: 153 ESSNKKQKNEETEEPA 168
Score = 56.2 bits (134), Expect = 3e-07
Identities = 41/159 (25%), Positives = 73/159 (45%), Gaps = 10/159 (6%)
Query: 3 KSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKI-AEVAAKQKKETKLQ 61
K +K+ K +++ ++ S+ ++ +E E E + S+ +E ++ +++ +
Sbjct: 18 KQAKEEKAKAVSSSSSESSSSSSSSSESESESESESESSSSSSSSDSESSSSSSSDSESE 77
Query: 62 -KVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEE 120
+ KKE S D SSS D + K K +K++ + SSSSS DS E+EE
Sbjct: 78 AETKKEESKDSSSSSSDSSSDEEEEEEKEETKK--EESKESSSSDSSSSSSSDSESEKEE 135
Query: 121 VIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPA 159
KK K E++ +ED S + E+PA
Sbjct: 136 SNDKK------RKSEDAEEEEDEESSNKKQKNEETEEPA 168
>NP14_HUMAN (Q14978) Nucleolar phosphoprotein p130 (Nucleolar 130
kDa protein) (140 kDa nucleolar phosphoprotein)
(Nopp140) (Nucleolar and coiled-body phosphoprotein 1)
Length = 699
Score = 173 bits (439), Expect = 1e-42
Identities = 169/519 (32%), Positives = 213/519 (40%), Gaps = 118/519 (22%)
Query: 3 KSSKKSATKVEAAAPVAA-APKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQ------K 55
KS+K K++A PVA A K A + E E++V K A V AK+ K
Sbjct: 59 KSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGK 118
Query: 56 KETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSS 115
K + S DD ED+K P +K K P KKAK SS SD DSS
Sbjct: 119 AAAKASESSSSEESRDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAK----SSDSDSDSS 174
Query: 116 DEEEEVIAKKP--TKVVV-------PK------KEESSSDEDSSSDEDSSSESDDEKPAA 160
E+E +KP T V V PK K + SSS SSS SDD +
Sbjct: 175 SEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEK 234
Query: 161 KVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDE----------------- 203
A P K P K AP K A SS SED S EE+E
Sbjct: 235 AAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSYAPP 294
Query: 204 PSAKQPKKEVAVKP---AVQKKKEESSSDDSSSES-----EDEKPAVK--VSAPSKVVPA 253
PSA PKK + +P AV+K++ SS+DSS ES E++KP K VS + P
Sbjct: 295 PSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPP 354
Query: 254 AVKNGAADSDSSDSDSSSDEDDDKK----------KPA--TKVAKKLPAAAPIKKV---- 297
A K + SDSSDSDSS D++ K KPA TK PAAAP + V
Sbjct: 355 AKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQ 414
Query: 298 -----EKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASS------------DSDD 340
+ SS +E S SS+EE K TT KP A K+A S S D
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATT--KPKATAKAALSLPAKQAPQGSRDSSSD 472
Query: 341 EDSSDSDSE---------------------------VKKDKMDVDESDSSEDSDEEDEKS 373
DSS S+ E KK K + S SS+DS EE+E+
Sbjct: 473 SDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEK 532
Query: 374 TK---TPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSK 409
K +P+ + A + +N ++ E E K
Sbjct: 533 LKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKK 571
Score = 140 bits (352), Expect = 1e-32
Identities = 144/462 (31%), Positives = 195/462 (42%), Gaps = 118/462 (25%)
Query: 2 PKSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQ 61
PK+ K T V A A PK A+ A + A + S+
Sbjct: 180 PKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSS---------------- 223
Query: 62 KVKKESSSDDDSSSEDEKPAPKVAP------LKTSVKNGTTPAKKAKPAPSSSSSDEDSS 115
SSS DDS E PK K VK TTP +K SSSS D S
Sbjct: 224 -----SSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRK-----SSSSEDSSSD 273
Query: 116 DEEEE------------------------VIAKKPTKVVVPKKEESSSDEDSSSDEDSSS 151
+EEE+ + +P K V K++ S EDSS + DSSS
Sbjct: 274 EEEEQKKPMKNKPGPYSYAPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSS 333
Query: 152 ESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQ--- 208
E +++KP P K +K + PAKK A SSS+S D DSSE+DE +K
Sbjct: 334 E-EEKKP------PTKAVVSKATTKPPPAKK---AAESSSDSSDSDSSEDDEAPSKPAGT 383
Query: 209 ----------PKKEVAVKPA-------------VQKKKEESSSDDSSSESEDE--KPAVK 243
K AVKPA + +K + SSS++ SS SE+E K V
Sbjct: 384 TKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVA 443
Query: 244 VSAPSKVVPAAVK-------NGAADSDSSDSDSSSDEDDDKKKPATKVAKK----LPAAA 292
+ P AA+ G+ DS SSDSDSSS E++++K + V KK AA
Sbjct: 444 TTKPKATAKAALSLPAKQAPQGSRDS-SSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAA 502
Query: 293 PIK----KVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKK------SASSDSDDED 342
P K K K+ESS+ SS+ S EE + K +P A K +A + ++
Sbjct: 503 PSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKN 562
Query: 343 SSDSDSEVKKDKMDVDESDS-SEDSDEEDEKSTKTPQ-KKVK 382
S + + E KK + V +S S + E K +TPQ KK+K
Sbjct: 563 SEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIK 604
Score = 137 bits (344), Expect = 1e-31
Identities = 141/427 (33%), Positives = 191/427 (44%), Gaps = 75/427 (17%)
Query: 43 KKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAK 102
+ +++EVA K K T + +SS D S K A P + NG AKKAK
Sbjct: 23 RDNQLSEVANKFAKATGATQQDANASSLLDIYSFWLKSAK--VPERKLQANGPV-AKKAK 79
Query: 103 PAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKK-------EESSSDEDSSSDEDSSSESDD 155
SSS S EDSS+EEEEV K VP K + ++ +SSS E+S + D+
Sbjct: 80 KKASSSDS-EDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESRDDDDE 138
Query: 156 EKPAAKVAVPAKKAPAKNG-SVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPK---- 210
E KK P + G A A KA P + SS+S+ D SSE++ P ++PK
Sbjct: 139 E--------DQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPV 190
Query: 211 ----------KEVAVKPAVQKKKEESSSDDSSS-----ESEDEKPAV--KVSAPSKVVPA 253
K P + K SSS SSS +SE+EK A K + P K V A
Sbjct: 191 TVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVA 250
Query: 254 AVKNGAADS----DSSDSDSSSDEDDDKKKP---------------ATKVAKKLPAAAPI 294
AA + SS DSSSDE++++KKP A K L P
Sbjct: 251 KAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSYAPPPSAPPPKKSLGTQPPK 310
Query: 295 KKVEKS---ESSDDESSES-SDEENDSKPATTTV-----AKPSAVKKSASSDSDDEDSSD 345
K VEK ESS+D S ES S E + KP T V KP KK+A S S DSSD
Sbjct: 311 KAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSS---DSSD 367
Query: 346 SDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKN--APKTPAAQT 403
SDS + D+ + ++++S + +TK+P K G+ K ++ +
Sbjct: 368 SDSS-EDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSS 426
Query: 404 ENEGSKT 410
E E S +
Sbjct: 427 EEESSSS 433
Score = 117 bits (292), Expect = 1e-25
Identities = 124/415 (29%), Positives = 181/415 (42%), Gaps = 73/415 (17%)
Query: 6 KKSATK--VEAAAPVAAAPKSAKKAKRAAE---DEVEKQVSAKKQKIAEV-------AAK 53
KK+ K V A APV AA +K+ + + DE E+Q K K A
Sbjct: 240 KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSYAPPPSAPP 299
Query: 54 QKKETKLQKVKK------------ESSSDDDSSSEDEKPAPKVAPLKTSVKNGTT---PA 98
KK Q KK +SS + DSSSE+EK P K V TT PA
Sbjct: 300 PKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPT----KAVVSKATTKPPPA 355
Query: 99 KKAKPAPSSSSSDEDSSDEEEE----------------VIAKKPT--KVVVPKKEESSSD 140
KKA + SS SSD DSS+++E V K P PK+
Sbjct: 356 KKAAES-SSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQ 414
Query: 141 E------DSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESE 194
+ DSSS E+ SS S++EK VA KA AK +++ PAK+A SS
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAK-AALSLPAKQAPQGSRDSSSDS 473
Query: 195 DDDSSEEDEPSA------KQPKKEVA----VKPAVQKKKEESSSDDSSSE--SEDEKPAV 242
D SSEE+E K+P+K KPA KK + SS+ SSS+ SE+E+ +
Sbjct: 474 DSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKL 533
Query: 243 K-VSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSE 301
K +P P A A + + + +S+E++++KK A V K + +KK +++E
Sbjct: 534 KGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSK---SGSLKKRKQNE 590
Query: 302 SSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMD 356
++ + + + + P T K + S+ E+ + DS V + D
Sbjct: 591 AAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFD 645
>NP14_RAT (P41777) Nucleolar phosphoprotein p130 (Nucleolar 130 kDa
protein) (140 kDa nucleolar phosphoprotein) (Nopp140)
(Nucleolar and coiled-body phosphoprotein 1)
Length = 704
Score = 162 bits (411), Expect = 2e-39
Identities = 149/434 (34%), Positives = 190/434 (43%), Gaps = 84/434 (19%)
Query: 38 KQVSAKKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTP 97
K K Q VA K KKET S S +DSS E++K K + P
Sbjct: 62 KAPKVKLQSNGPVAKKAKKETS------SSDSSEDSSEEEDKAQVPTQKAAAPAKRASLP 115
Query: 98 ---AKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVV-----------PKKEESSSDEDS 143
K A A SSSS+E S +EEE+ KKP + PKK ESS E
Sbjct: 116 QHAGKAAAKASESSSSEESSEEEEEKDKKKKPVQQKAVKPQAKAVRPPPKKAESSESESD 175
Query: 144 SSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQP---------APSSSSESE 194
SS ED + ++ K AA A KA K + P KAQP + SSSS S
Sbjct: 176 SSSEDEAPQTQKPKAAATAAKAPTKAQTKAPAKPGPPAKAQPKAANGKAGSSSSSSSSSS 235
Query: 195 DDDSSEEDEPSAK----QPKKEVAVKPAVQ----KKKEESSSDDSSSESEDE--KPAVKV 244
DDS EE + +A PKK+V K V+ ++ SSS+DSSSE E+E KP K
Sbjct: 236 SDDSEEEKKAAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSSSEDSSSEEEEEQKKPMKKK 295
Query: 245 SAPSKVVP------------------AAVKNGAADSD---SSDSDSSSDEDDDKKKPATK 283
+ P VP AA + ADS S +SDSSS+E+ KK PA
Sbjct: 296 AGPYSSVPPPSVSLSKKSVGAQSPKKAAAQTQPADSSADSSEESDSSSEEE--KKTPAKT 353
Query: 284 VAKKLPAA-APIKKVEKSESSDDESSESSDEENDSKPATTTVA---------KPSAVKKS 333
V K PA AP+KK +S SSD S+SS++E +KP + T + KP A K
Sbjct: 354 VVSKTPAKPAPVKKKAES-SSDSSDSDSSEDEAPAKPVSATKSPLSKPAVTPKPPAAKAV 412
Query: 334 ASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGK 393
A+ S +ES SSE +E +KS TP+ +V + K
Sbjct: 413 ATPKQPAGSGQKPQSRKADSSSSEEESSSSE--EEATKKSVTTPKARV---------TAK 461
Query: 394 NAPKTPAAQTENEG 407
AP PA Q G
Sbjct: 462 AAPSLPAKQAPRAG 475
Score = 162 bits (410), Expect = 3e-39
Identities = 164/474 (34%), Positives = 217/474 (45%), Gaps = 85/474 (17%)
Query: 7 KSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAK-QKKETKLQKVKK 65
K A+ + A AA + ++ ++E+E EK KK+ + + A K Q K + K
Sbjct: 110 KRASLPQHAGKAAAKASESSSSEESSEEEEEKD--KKKKPVQQKAVKPQAKAVRPPPKKA 167
Query: 66 ESS-SDDDSSSEDEKPA---PKVA------PLKTSVKNGTTPAKKAKPAP---------- 105
ESS S+ DSSSEDE P PK A P K K P AK P
Sbjct: 168 ESSESESDSSSEDEAPQTQKPKAAATAAKAPTKAQTKAPAKPGPPAKAQPKAANGKAGSS 227
Query: 106 SSSSSDEDSSDEEEEVIAKKPTKVVVPKKE---------ESSSDEDSSSDEDSSSESDDE 156
SSSSS S D EEE A P K PKK+ ++ + SSS EDSSSE ++E
Sbjct: 228 SSSSSSSSSDDSEEEKKAAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSSSEDSSSEEEEE 287
Query: 157 --KPAAKVAVPAKKAPAKNGSVT-------APAKKA---QPAPSSSSESEDDDSSEEDEP 204
KP K A P P + S++ +P K A QPA SS+ SE+ DSS E+E
Sbjct: 288 QKKPMKKKAGPYSSVPPPSVSLSKKSVGAQSPKKAAAQTQPADSSADSSEESDSSSEEEK 347
Query: 205 S--AKQPKKEVAVKPAVQKKKEESSSDDSSSES-EDEKPAVKVSAPSKVV--------PA 253
AK + KPA KKK ESSSD S S+S EDE PA VSA + P
Sbjct: 348 KTPAKTVVSKTPAKPAPVKKKAESSSDSSDSDSSEDEAPAKPVSATKSPLSKPAVTPKPP 407
Query: 254 AVKNGA----------------ADSDSSDSDSSSDEDDDKKKPATKVAKKLPA-AAPIKK 296
A K A ADS SS+ +SSS E++ KK T ++ A AAP
Sbjct: 408 AAKAVATPKQPAGSGQKPQSRKADSSSSEEESSSSEEEATKKSVTTPKARVTAKAAPSLP 467
Query: 297 VEKSESSDDESSESSD-EENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKM 355
+++ + +SS SD E + S+ T KP A KK+A + + + VKK
Sbjct: 468 AKQAPRAGGDSS--SDSESSSSEEEKKTPPKPPAKKKAAGA------AVPKPTPVKKAAA 519
Query: 356 D-VDESDSSEDSDEEDEKSTK---TPQKKVKDVEMVDASSGKNAPKTPAAQTEN 405
+ S SSEDS EE++K K TP+ + V AS A K + E+
Sbjct: 520 ESSSSSSSSEDSSEEEKKKPKSKATPKPQAGKANGVPASQNGKAGKESEEEEED 573
Score = 152 bits (385), Expect = 2e-36
Identities = 153/513 (29%), Positives = 202/513 (38%), Gaps = 112/513 (21%)
Query: 3 KSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAK--KQKIAEVAAK----QKK 56
KS+K K+++ PVA K + ++ED E++ A+ QK A A + Q
Sbjct: 59 KSTKAPKVKLQSNGPVAKKAKKETSSSDSSEDSSEEEDKAQVPTQKAAAPAKRASLPQHA 118
Query: 57 ETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPS---SSSSDED 113
K + SSS++ S E+EK K + +VK AK +P P SS S+ D
Sbjct: 119 GKAAAKASESSSSEESSEEEEEKDKKKKPVQQKAVK---PQAKAVRPPPKKAESSESESD 175
Query: 114 SSDEEE----------EVIAKKPTKVVV--------PKKEE---SSSDEDSSSDEDSSSE 152
SS E+E AK PTK P K + ++ SSS SSS
Sbjct: 176 SSSEDEAPQTQKPKAAATAAKAPTKAQTKAPAKPGPPAKAQPKAANGKAGSSSSSSSSSS 235
Query: 153 SDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDE--------- 203
SDD + K A P KK K V K AP+ S S +D SSEE+E
Sbjct: 236 SDDSEEEKKAAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSSSEDSSSEEEEEQKKPMKKK 295
Query: 204 ---------PSAKQPKKEVAV----KPAVQKKKEESSSD-----DSSSESEDEKPAVKVS 245
PS KK V K A Q + +SS+D DSSSE E + PA V
Sbjct: 296 AGPYSSVPPPSVSLSKKSVGAQSPKKAAAQTQPADSSADSSEESDSSSEEEKKTPAKTVV 355
Query: 246 APSKVVPAAVKNGA-ADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKS---- 300
+ + PA VK A + SDSSDSDSS DE K ATK PA P K+
Sbjct: 356 SKTPAKPAPVKKKAESSSDSSDSDSSEDEAPAKPVSATKSPLSKPAVTPKPPAAKAVATP 415
Query: 301 ----------------ESSDDESSESSDEENDSKPATTTVAK---------PSAVKKSAS 335
SS +E S SS+EE K TT A+ P+ A
Sbjct: 416 KQPAGSGQKPQSRKADSSSSEEESSSSEEEATKKSVTTPKARVTAKAAPSLPAKQAPRAG 475
Query: 336 SDSDDEDSSDSDSEVKK----------------------DKMDVDESDSSEDSDEEDEKS 373
DS + S S E KK K + S SS S++ E+
Sbjct: 476 GDSSSDSESSSSEEEKKTPPKPPAKKKAAGAAVPKPTPVKKAAAESSSSSSSSEDSSEEE 535
Query: 374 TKTPQKKVKDVEMVDASSGKNAPKTPAAQTENE 406
K P+ K ++G A + A E+E
Sbjct: 536 KKKPKSKATPKPQAGKANGVPASQNGKAGKESE 568
Score = 152 bits (384), Expect = 3e-36
Identities = 147/452 (32%), Positives = 216/452 (47%), Gaps = 70/452 (15%)
Query: 3 KSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIA---EVAAKQKKETK 59
K + + +AA A + S+ + + + E EK+ +A +K A +V AK +
Sbjct: 208 KPGPPAKAQPKAANGKAGSSSSSSSSSSSDDSEEEKKAAAPLKKTAPKKQVVAKAPVKVT 267
Query: 60 LQKVKKESSSDDDSSSEDEK---------------PAPKVAPLKTSVKNGTTPAKKA--- 101
+K SSS+D SS E+E+ P P V+ K SV G KKA
Sbjct: 268 AAPTQKSSSSEDSSSEEEEEQKKPMKKKAGPYSSVPPPSVSLSKKSV--GAQSPKKAAAQ 325
Query: 102 -KPAPSSSSSDE--DSSDEEEE------VIAKKPTKVV-VPKKEESSSDE-DSSSDED-- 148
+PA SS+ S E DSS EEE+ V++K P K V KK ESSSD DS S ED
Sbjct: 326 TQPADSSADSSEESDSSSEEEKKTPAKTVVSKTPAKPAPVKKKAESSSDSSDSDSSEDEA 385
Query: 149 -----SSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDE 203
S+++S KPA PA KA A +K Q + SS SE++ SS E+E
Sbjct: 386 PAKPVSATKSPLSKPAVTPKPPAAKAVATPKQPAGSGQKPQSRKADSSSSEEESSSSEEE 445
Query: 204 PSAKQ---PKKEVAVK-----PAVQKKKE--ESSSDDSSSESEDEK------PAVKVSAP 247
+ K PK V K PA Q + +SSSD SS SE+EK PA K +A
Sbjct: 446 ATKKSVTTPKARVTAKAAPSLPAKQAPRAGGDSSSDSESSSSEEEKKTPPKPPAKKKAAG 505
Query: 248 SKV-VPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSES--SD 304
+ V P VK AA+S SS S S +++KKKP +K K P A V S++ +
Sbjct: 506 AAVPKPTPVKKAAAESSSSSSSSEDSSEEEKKKPKSKATPK-PQAGKANGVPASQNGKAG 564
Query: 305 DESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSE 364
ES E ++ +K A T KP + KK +++ DE ++ +VK ++ ++
Sbjct: 565 KESEEEEEDTEQNKKAAGT--KPGSGKKRKHNETADEAATPQSKKVKL------QTPNTF 616
Query: 365 DSDEEDEKSTKTPQKKVKDVEM-VDASSGKNA 395
++ EK +P ++V++ E+ VD+ N+
Sbjct: 617 PKRKKGEKRASSPFRRVREEEIEVDSRVADNS 648
Score = 142 bits (359), Expect = 2e-33
Identities = 137/456 (30%), Positives = 180/456 (39%), Gaps = 93/456 (20%)
Query: 4 SSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQKV 63
S +S + E AP PK+A A +A K + K A Q K +
Sbjct: 170 SESESDSSSEDEAPQTQKPKAAATAAKAPT----KAQTKAPAKPGPPAKAQPKAANGKAG 225
Query: 64 KKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAK-----KAKPAPSSSSSDEDSSDEE 118
SSS SS + E+ APLK + AK A P SSSS++ SS+EE
Sbjct: 226 SSSSSSSSSSSDDSEEEKKAAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSSSEDSSSEEE 285
Query: 119 EE--------------------VIAKKPTKVVVPKK-----EESSSDEDSSSDEDSSSES 153
EE ++KK PKK + + S DSS + DSSSE
Sbjct: 286 EEQKKPMKKKAGPYSSVPPPSVSLSKKSVGAQSPKKAAAQTQPADSSADSSEESDSSSEE 345
Query: 154 DDEKPAAKVA--VPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEP-----SA 206
+ + PA V PAK AP K KKA+ SSS+S D DSSE++ P +
Sbjct: 346 EKKTPAKTVVSKTPAKPAPVK--------KKAE----SSSDSSDSDSSEDEAPAKPVSAT 393
Query: 207 KQPKKEVAVKP--------------------AVQKKKEESSSDDSSSESEDEKPAVKVSA 246
K P + AV P +K + SSS++ SS SE+E V+
Sbjct: 394 KSPLSKPAVTPKPPAAKAVATPKQPAGSGQKPQSRKADSSSSEEESSSSEEEATKKSVTT 453
Query: 247 PSKVV--------PAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKK-----LPAAAP 293
P V PA A SSDS+SSS E++ K P KK +P P
Sbjct: 454 PKARVTAKAAPSLPAKQAPRAGGDSSSDSESSSSEEEKKTPPKPPAKKKAAGAAVPKPTP 513
Query: 294 IKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSD------DEDSSDSD 347
+KK SS SSE S EE KP + KP A K + S + + + D
Sbjct: 514 VKKAAAESSSSSSSSEDSSEEEKKKPKSKATPKPQAGKANGVPASQNGKAGKESEEEEED 573
Query: 348 SEVKKDKMDVDESDSSEDSDEEDEKSTKTPQ-KKVK 382
+E K + E TPQ KKVK
Sbjct: 574 TEQNKKAAGTKPGSGKKRKHNETADEAATPQSKKVK 609
Score = 122 bits (306), Expect = 3e-27
Identities = 117/407 (28%), Positives = 172/407 (41%), Gaps = 56/407 (13%)
Query: 1 MPKSSKKSATKVEAAAPVAAAP--KSAKKAKRAAEDEVEKQVSAKKQ------------- 45
+ K++ K +A V AAP KS+ ++E+E E++ KK+
Sbjct: 249 LKKTAPKKQVVAKAPVKVTAAPTQKSSSSEDSSSEEEEEQKKPMKKKAGPYSSVPPPSVS 308
Query: 46 -KIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAK----K 100
V A+ K+ Q +SS+D S+ K P KT V TPAK K
Sbjct: 309 LSKKSVGAQSPKKAAAQTQPADSSADSSEESDSSSEEEKKTPAKTVVSK--TPAKPAPVK 366
Query: 101 AKPAPSSSSSDEDSSDEE--------------EEVIAKKP--TKVVVPKKEESSSDE--- 141
K SS SSD DSS++E + + KP K V K+ + S +
Sbjct: 367 KKAESSSDSSDSDSSEDEAPAKPVSATKSPLSKPAVTPKPPAAKAVATPKQPAGSGQKPQ 426
Query: 142 ----DSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPS-SSSESEDD 196
DSSS E+ SS S++E V P + AK + + PAK+A A SSS+SE
Sbjct: 427 SRKADSSSSEEESSSSEEEATKKSVTTPKARVTAK-AAPSLPAKQAPRAGGDSSSDSESS 485
Query: 197 DSSEEDEPSAKQPKKEVAVKPAVQK----KKEESSSDDSSSESEDEKPAVKVSAPSKVVP 252
S EE + K P K+ A AV K KK + S SSS SED K SK P
Sbjct: 486 SSEEEKKTPPKPPAKKKAAGAAVPKPTPVKKAAAESSSSSSSSEDSSEEEKKKPKSKATP 545
Query: 253 ---AAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSE 309
A NG S + + S+E+++ + K A P + KK + +E++D+ ++
Sbjct: 546 KPQAGKANGVPASQNGKAGKESEEEEEDTEQNKKAAGTKPGSG--KKRKHNETADEAATP 603
Query: 310 SSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMD 356
S + P T K + S+ E+ + DS V + D
Sbjct: 604 QSKKVKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFD 650
>ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog
(X-linked nuclear protein-1)
Length = 1359
Score = 129 bits (324), Expect = 2e-29
Identities = 111/396 (28%), Positives = 175/396 (44%), Gaps = 44/396 (11%)
Query: 30 RAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKT 89
R E+E +++ + K ++ E K + + K +K SSS++D E+E P
Sbjct: 25 RQIENERKEKRAQKLKEKREREGKPPPKKRPAKKRKASSSEEDDDDEEESPRKS------ 78
Query: 90 SVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDEDS 149
+KK++ S S ++S +EE+ +K KV KKE+S +SS ED
Sbjct: 79 --------SKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDE 130
Query: 150 SSESDDEKPAAKVAVPAKKAPAKNGSVTAPAK------KAQPAPSSSSESEDDDSSEEDE 203
S+ + E+ + K + KK + S + + K S +E + S+EDE
Sbjct: 131 DSDEEREQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDEDE 190
Query: 204 PSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKV---------SAPSKVVPAA 254
+K+ KK + K K + ES S+D + +K + KV AP K
Sbjct: 191 KPSKKSKKGLKKK---AKSESESESEDEKEVKKSKKKSKKVVKKESESEDEAPEKKKTEK 247
Query: 255 VKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDE- 313
K S+ S SDE++++K+ + K KK P A +KK+ SSD+ES ES E
Sbjct: 248 RKRSKTSSEESSESEKSDEEEEEKESSPKPKKKKPLA--VKKL----SSDEESEESDVEV 301
Query: 314 -ENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDE--SDSSEDSDEED 370
K T+ S +K S+S+ D + S+ K K + E SDSSE S +
Sbjct: 302 LPQKKKRGAVTLISDSEDEKDQKSESEASDVEEKVSKKKAKKQESSESGSDSSEGSITVN 361
Query: 371 EKSTK--TPQKKVKDVEMVDASSGKNAPKTPAAQTE 404
KS K P+KK K + M + K A+ E
Sbjct: 362 RKSKKKEKPEKKKKGIIMDSSKLQKETIDAERAEKE 397
Score = 116 bits (291), Expect = 2e-25
Identities = 127/438 (28%), Positives = 193/438 (43%), Gaps = 80/438 (18%)
Query: 2 PKSSKKSATKVEAAAPVAAAP-KSAKKAKRAAE-----DEVEKQVSAKKQKIAEVAAKQK 55
P +K+++ E +P KS+KK+++ A+ DE +++ KK K + ++K
Sbjct: 55 PAKKRKASSSEEDDDDEEESPRKSSKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQKK 114
Query: 56 KETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSS 115
KE +K SS D+DS E E+ + K +KK K SS SS+E S
Sbjct: 115 KEKSKKKRTTSSSEDEDSDEEREQKSKK-------------KSKKTKKQTSSESSEE--S 159
Query: 116 DEEEEVIAKKPTKVVVPKK-----EESSSDEDSS----------SDEDSSSESDDEKPAA 160
+EE +V K K KK EES DE S + +S SES+DEK
Sbjct: 160 EEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKGLKKKAKSESESESEDEKEVK 219
Query: 161 KVAVPAKKAPAKNG---------SVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKK 211
K +KK K T K+++ + SSESE D EE++ S+ +PKK
Sbjct: 220 KSKKKSKKVVKKESESEDEAPEKKKTEKRKRSKTSSEESSESEKSDEEEEEKESSPKPKK 279
Query: 212 EVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSS 271
+ KP KK SSD+ S ES+ E V+P K GA + SDS
Sbjct: 280 K---KPLAVKK---LSSDEESEESDVE-----------VLPQKKKRGAV---TLISDSED 319
Query: 272 DEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVK 331
++D + A+ V +K+ + KK E SES D S S SK KP K
Sbjct: 320 EKDQKSESEASDVEEKV-SKKKAKKQESSESGSDSSEGSITVNRKSKKK----EKPEKKK 374
Query: 332 KSASSDSD--DEDSSDSDSEVKKDKMDVDESDSS------EDSDEEDEKSTKT-PQKKVK 382
K DS +++ D++ K+ + +++ E+ ++ E T T Q+K+K
Sbjct: 375 KGIIMDSSKLQKETIDAERAEKERRKRLEKKQKEFNGIVLEEGEDLTEMLTGTSSQRKLK 434
Query: 383 DVEM-VDASSGKNAPKTP 399
V + D+S+ K P
Sbjct: 435 SVVLDPDSSTVDEESKKP 452
Score = 99.0 bits (245), Expect = 4e-20
Identities = 92/353 (26%), Positives = 147/353 (41%), Gaps = 62/353 (17%)
Query: 117 EEEEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSV 176
E+ E K P K KK ++SS E+ DE+ S P K+
Sbjct: 41 EKREREGKPPPKKRPAKKRKASSSEEDDDDEEES-------------------PRKS--- 78
Query: 177 TAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESE 236
+KK++ S SES++ D E+ + S + K + K +KK+ SSS+D S+ E
Sbjct: 79 ---SKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDEDSDEE 135
Query: 237 DEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKK 296
E+ + K S +K S SS+E ++++K K +KK + K+
Sbjct: 136 REQKSKKKSKKTK--------------KQTSSESSEESEEERK--VKKSKKNKEKSVKKR 179
Query: 297 VEKSESSDDE---------------SSESSDEENDSKPATTTVAKPSAVKKSASSDSDDE 341
E SE SD++ SES E D K + K V K S D+
Sbjct: 180 AETSEESDEDEKPSKKSKKGLKKKAKSESESESEDEKEVKKSKKKSKKVVKKESESEDEA 239
Query: 342 DSSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQ-KKVKDVEMVDASSGKNAPKTPA 400
+ K+ K +ES SE SDEE+E+ +P+ KK K + + SS + + ++
Sbjct: 240 PEKKKTEKRKRSKTSSEESSESEKSDEEEEEKESSPKPKKKKPLAVKKLSSDEESEESDV 299
Query: 401 ---AQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATDEDGRFKG 450
Q + G+ TL + Q+S+ E D E V + A ++ G
Sbjct: 300 EVLPQKKKRGAVTLISDSEDEKDQKSESE--ASDVEEKVSKKKAKKQESSESG 350
Score = 36.6 bits (83), Expect = 0.22
Identities = 25/76 (32%), Positives = 37/76 (47%), Gaps = 4/76 (5%)
Query: 302 SSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESD 361
SSDDE S S ++N +KP A K S D D+ED D+ + +D + +
Sbjct: 851 SSDDEGS-SKKKKNGNKPEIKKTAPQKKRKFLNSDDEDEEDGEDTAMAILQDGIRQSKRL 909
Query: 362 SSEDSDEEDEKSTKTP 377
+ E++D D T TP
Sbjct: 910 AGEEADLRD---TDTP 922
Score = 31.6 bits (70), Expect = 7.0
Identities = 28/120 (23%), Positives = 45/120 (37%), Gaps = 22/120 (18%)
Query: 229 DDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKL 288
D SESE E + K+G+ SSD++ KK ++
Sbjct: 824 DGDGSESESE--------------GSFKSGSESDSGKSVVLSSDDEGSSKKKKNGNKPEI 869
Query: 289 PAAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDS 348
AP KK K +SDDE E ++ T +++S ++ D D+D+
Sbjct: 870 KKTAPQKK-RKFLNSDDEDEEDGED-------TAMAILQDGIRQSKRLAGEEADLRDTDT 921
>NFH_HUMAN (P12036) Neurofilament triplet H protein (200 kDa
neurofilament protein) (Neurofilament heavy polypeptide)
(NF-H)
Length = 1026
Score = 125 bits (313), Expect = 5e-28
Identities = 119/396 (30%), Positives = 174/396 (43%), Gaps = 67/396 (16%)
Query: 3 KSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQK------K 56
K+ KS K A +PV A KS +KAK ++E + AK E + +K +
Sbjct: 677 KAEAKSPEK--AKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 734
Query: 57 ETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSD 116
E K + K ++ S E K K L TPAK+ +P+ ++ S
Sbjct: 735 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 794
Query: 117 EEEEVIAKKPTKVVVPKKEESSSDEDS--SSDEDSSSESDDEKPA-AKVAVPAKKAPAKN 173
+EEV K P K P KE++ + E +E S ++EKP KV P KKA
Sbjct: 795 VKEEV--KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA---- 848
Query: 174 GSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVK--PAVQKKKEESSSDDS 231
+ + AP++ E DS +E+ P + PK +V K PAV+K KE S +
Sbjct: 849 --------EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE-SKVEAK 899
Query: 232 SSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLP-- 289
E+ED+K KV P K PA V+ ++D K K T+VAKK P
Sbjct: 900 KEEAEDKK---KVPTPEKEAPAKVE---------------VKEDAKPKEKTEVAKKEPDD 941
Query: 290 --AAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSD 347
A P K EK E++ ++ + + EE KP KP K A + DD+ S
Sbjct: 942 AKAKEPSKPAEKKEAAPEK--KDTKEEKAKKPE----EKP---KTEAKAKEDDKTLSKEP 992
Query: 348 SEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKD 383
S+ K +K +E S D+K +K P+K +D
Sbjct: 993 SKPKAEK--------AEKSSSTDQKDSKPPEKATED 1020
Score = 115 bits (287), Expect = 5e-25
Identities = 123/412 (29%), Positives = 174/412 (41%), Gaps = 35/412 (8%)
Query: 7 KSATKVEAAAPVAAAPKSAKKAKRAAEDEV---EKQVSAKKQKIAEVAAKQKKETKLQKV 63
KS K EA +P A KS +KAK ++E EK S +K K E + E V
Sbjct: 619 KSPVKEEAKSP--AEVKSPEKAKSPTKEEAKSPEKAKSPEKAKSPEKEEAKSPEKAKSPV 676
Query: 64 KKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAK-PAPSSSSSDEDSSDEEEEVI 122
K E+ S + + S + A K+ VK +KAK P + S E + +E
Sbjct: 677 KAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEE- 735
Query: 123 AKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKK 182
AK P K P KEE+ S E + S E + + V P K PAK +PA K
Sbjct: 736 AKTPEKAKSPVKEEAKSPEKAKSPEKAKT--------LDVKSPEAKTPAKE-EARSPADK 786
Query: 183 AQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPA- 241
P + S E+ S E+ AK P KE A P + K+E + S E+EKP
Sbjct: 787 F-PEKAKSPVKEEVKSPEK----AKSPLKEDAKAPEKEIPKKE---EVKSPVKEEEKPQE 838
Query: 242 VKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVA-KKLPAAAPIK--KVE 298
VKV P K K A DS +E K+ P KV KK PA K KVE
Sbjct: 839 VKVKEPPKKAEEE-KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 897
Query: 299 --KSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMD 356
K E+ D + + ++E +K AKP + A + DD + + +K +
Sbjct: 898 AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAA 957
Query: 357 VDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGS 408
++ D+ E+ ++ E+ KT K +D D + K K A + E S
Sbjct: 958 PEKKDTKEEKAKKPEEKPKTEAKAKED----DKTLSKEPSKPKAEKAEKSSS 1005
Score = 114 bits (286), Expect = 6e-25
Identities = 113/428 (26%), Positives = 181/428 (41%), Gaps = 40/428 (9%)
Query: 7 KSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKL-QKVKK 65
KS K EA +P A KS +KAK A++E + AK + E AK E K +K K
Sbjct: 531 KSPEKEEAKSP--AEVKSPEKAKSPAKEEAKSPPEAKSPEKEE--AKSPAEVKSPEKAKS 586
Query: 66 ESSSDDDSSSEDEKPAPKVAPLKTSVKN---GTTPAKKAKPAPSSSSSDEDSSDEEEEVI 122
+ + S +E + P +P+K K+ +P K+ +P+ S E + +E
Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA 646
Query: 123 -----AKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAK-----KAPAK 172
AK P K P+KEE+ S E + S + ++S EK + V AK K+P K
Sbjct: 647 KSPEKAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSP-EKAKSPVKAEAKSPEKAKSPVK 705
Query: 173 NGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPS----AKQPKKEVAVKPAVQKKKEESSS 228
+P K P + E S ++E AK P KE A P K E++ +
Sbjct: 706 E-EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT 764
Query: 229 DDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKL 288
D S + +P+ P K+ + S + S +D K P ++ KK
Sbjct: 765 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE 824
Query: 289 PAAAPIKKVEKSESSDDESSESSDEENDSKPATTTV------AKPSAVKKSASSDSDDED 342
+P+K+ EK + + EE + PAT K A KK A +E
Sbjct: 825 EVKSPVKEEEKPQEVKVKEPPKKAEE-EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK 883
Query: 343 SSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKV-KDVEMVDASSGKNAPKTPAA 401
+ + K+ K++ + ++ ED+K TP+K+ VE+ + + K KT A
Sbjct: 884 KEPAVEKPKESKVEAKKEEA------EDKKKVPTPEKEAPAKVEVKEDAKPKE--KTEVA 935
Query: 402 QTENEGSK 409
+ E + +K
Sbjct: 936 KKEPDDAK 943
Score = 101 bits (251), Expect = 7e-21
Identities = 113/452 (25%), Positives = 185/452 (40%), Gaps = 53/452 (11%)
Query: 1 MPK-SSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETK 59
+PK S + KV++ + KS K+ E E QV+ EV +++KE K
Sbjct: 426 LPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTE------EVTEEEEKEAK 479
Query: 60 LQKVKKESSSDDDSSSEDEK-----PAPKVA--------PLKTSVKN---GTTPAKKAKP 103
++ K+E +++ + E+ PA + A P+K K+ +P K+
Sbjct: 480 EEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK 539
Query: 104 APSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVA 163
+P+ S E + +E AK P + P+KEE+ S + S E + S + +E AK
Sbjct: 540 SPAEVKSPEKAKSPAKEE-AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEE---AKSP 595
Query: 164 VPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKK 223
AK V AK A S E + + AK P KE A P K
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655
Query: 224 EESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDK-----K 278
E++ S + EK V A +K A A++ S + S +++ K K
Sbjct: 656 EKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAK 715
Query: 279 KPATKVAK-----KLPAAAPIKKVEKSESSDDESSESSDE-ENDSKPATTTVAKPSA--- 329
P + AK K P K EK++S E ++S ++ ++ K T V P A
Sbjct: 716 SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP 775
Query: 330 VKKSASSDSD---DEDSSDSDSEVK---KDKMDVDESDSSEDSDEEDEKSTKTPQK---- 379
K+ A S +D ++ S EVK K K + E + + + ++ K+P K
Sbjct: 776 AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 835
Query: 380 --KVKDVEMVDASSGKNAPKTPAAQTENEGSK 409
+VK E + + AP TP + + + K
Sbjct: 836 PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKK 867
Score = 86.3 bits (212), Expect = 2e-16
Identities = 87/353 (24%), Positives = 139/353 (38%), Gaps = 33/353 (9%)
Query: 82 PKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDE 141
PK+ + T +K + K + + EE +V + + KEE +E
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486
Query: 142 DSSSDEDSSSESDDEK--PAAKVAVPAK--KAPAKN-----GSVTAPAKKAQPAPSSSSE 192
+ +E++ ++ K PA + A P K K+P K +P K+ +P+
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546
Query: 193 SEDDDSSEEDE----PSAKQPKKEVAVKPAVQKK--------KEESSSDDSSSESEDEKP 240
E S ++E P AK P+KE A PA K KEE+ S + E K
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 241 AVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKS 300
VK A S PA K+ + S ++ S E K K TK K P A K EK+
Sbjct: 607 PVKEEAKS---PAEAKSPVKEEAKSPAEVKSPE---KAKSPTKEEAKSPEKA--KSPEKA 658
Query: 301 ESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDES 360
+S + E E+ E P P K +++ + + S VK++ +++
Sbjct: 659 KSPEKE--EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK--AKSPVKEEAKSPEKA 714
Query: 361 DSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFV 413
S + + + K+P K+ S K K+P E +KTL V
Sbjct: 715 KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 767
Score = 83.2 bits (204), Expect = 2e-15
Identities = 82/300 (27%), Positives = 131/300 (43%), Gaps = 38/300 (12%)
Query: 7 KSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQKVKKE 66
KS K EA +P A KS +KAK E + AK++ A A + E VK+E
Sbjct: 743 KSPVKEEAKSPEKA--KSPEKAKTLDVKSPEAKTPAKEE--ARSPADKFPEKAKSPVKEE 798
Query: 67 SSSDDDSSS---EDEKPAPKVAPLKTSVKNGTT------------PAKKAKP--APSSSS 109
S + + S ED K K P K VK+ P KKA+ AP++
Sbjct: 799 VKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK 858
Query: 110 SDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKA 169
++E ++EE K+ K V +K+E + ++ S ++ E ++K KV P K+A
Sbjct: 859 TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKK--KVPTPEKEA 916
Query: 170 PAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSD 229
PAK + A+P E + E D+ AK+P K K A +KK+ +
Sbjct: 917 PAK----VEVKEDAKP-----KEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD---TK 964
Query: 230 DSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDK---KKPATKVAK 286
+ ++ +EKP + A + + ++ ++ SS+D+ D K K K AK
Sbjct: 965 EEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1024
Score = 62.4 bits (150), Expect = 4e-09
Identities = 64/243 (26%), Positives = 102/243 (41%), Gaps = 40/243 (16%)
Query: 13 EAAAPVAAAPKSAKKAKRAAEDEV---EKQVSAKKQKIAEVAAKQKKETKLQKVKKESSS 69
+A +PV KS +KAK +++ EK++ K+ EV + K+E K Q+VK +
Sbjct: 790 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE----EVKSPVKEEEKPQEVKVKEPP 845
Query: 70 DDDSSSEDEKPA-PKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPT- 127
+ E++ PA PK K S K + KP +E +V AKK
Sbjct: 846 K--KAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 903
Query: 128 ----KVVVPKKE-----ESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKK---APAKNGS 175
KV P+KE E D + + + D+ A + + PA+K AP K +
Sbjct: 904 EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT 963
Query: 176 VTAPAKKAQPAPSSSSESEDDD-----------------SSEEDEPSAKQPKKEVAVKPA 218
AKK + P + +++++DD SS D+ +K P+K K A
Sbjct: 964 KEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1023
Query: 219 VQK 221
K
Sbjct: 1024 KGK 1026
Score = 61.6 bits (148), Expect = 6e-09
Identities = 62/224 (27%), Positives = 90/224 (39%), Gaps = 38/224 (16%)
Query: 3 KSSKKSATKVEAA---APVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAA-----KQ 54
K KS K E V PK A++ K A + E++ +KK++ + A ++
Sbjct: 823 KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 882
Query: 55 KKETKLQKVKKESSSDDDSSSEDEKPAP---KVAPLKTSVKNGTTPAKK---AKPAPSSS 108
KKE ++K K+ +ED+K P K AP K VK P +K AK P +
Sbjct: 883 KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDA 942
Query: 109 SSDEDSSDEEEEVIA--KKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPA 166
+ E S E++ A KK TK KK E ++ + ED + S
Sbjct: 943 KAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS------------- 989
Query: 167 KKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPK 210
K P+K KA+ A SSS + D E K K
Sbjct: 990 -KEPSK--------PKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1024
Score = 59.3 bits (142), Expect = 3e-08
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 13/177 (7%)
Query: 2 PKSS-KKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKL 60
PK+ KK + K EA A PK +K + A E E +V AKK+ E K+K T
Sbjct: 857 PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE---EAEDKKKVPTPE 913
Query: 61 QKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEE 120
++ + +D+ +++ K P K + PA+K + AP + E+ + + EE
Sbjct: 914 KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEE 973
Query: 121 VIAKKPTKVVVPKKEESSSDEDSS-----SDEDSSSESDDEKPAAKVAVPAKKAPAK 172
K T+ + +++ S E S +++ SS++ D KP K A K A K
Sbjct: 974 ---KPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK-ATEDKAAKGK 1026
>DSPP_HUMAN (Q9NZW4) Dentin sialophosphoprotein precursor [Contains:
Dentin phosphoprotein (Dentin phosphophoryn) (DPP);
Dentin sialoprotein (DSP)]
Length = 1253
Score = 120 bits (302), Expect = 9e-27
Identities = 93/372 (25%), Positives = 160/372 (43%), Gaps = 14/372 (3%)
Query: 67 SSSDDDSSSEDEKPAPKVAPLKT-SVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKK 125
S S D S S D + + K+ S K+ + + + SS S+ DSSD + +
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 126 PTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQP 185
+ SSD SSSD SSS+S + ++ + + + + + S ++ + +
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS 721
Query: 186 APSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSS-----SESEDEKP 240
+ SS+S S D DSS + S + + + S+S DSS S+S D
Sbjct: 722 SDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 241 AVKVSAPSKVVPAAVKNGAADS-DSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEK 299
+ + S ++ + ++DS +SSDS SSD D ++ + ++ +
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 300 SESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSD-------SDSEVKK 352
S+SSD S SD N S + ++ + S+ ++S SD DSSD SDS
Sbjct: 842 SDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSS 901
Query: 353 DKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLF 412
+ D D SDSS SD D ++ + + ++S N+ + + + S +
Sbjct: 902 NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 961
Query: 413 VGNLSFSVQRSD 424
G+ S S SD
Sbjct: 962 SGDSSNSSDSSD 973
Score = 116 bits (290), Expect = 2e-25
Identities = 89/351 (25%), Positives = 153/351 (43%), Gaps = 6/351 (1%)
Query: 64 KKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIA 123
+ +SS+ DSS + + + + + + + SS+SSD DSSD +
Sbjct: 858 RSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 917
Query: 124 KKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKA 183
+ + +SSD +SSD +SS+S D ++ + + + N S ++ + +
Sbjct: 918 SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSS 977
Query: 184 QPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDS-SSESEDEKPAV 242
+ SS+S D S D + + +SSD S SS+S D +
Sbjct: 978 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSDSSDSS 1037
Query: 243 KVSAPSKVVPAAVKNGAAD-SDSSDSDSSSDEDDDK-KKPATKVAKKLPAAAPIKKVEKS 300
S S ++ + ++D SDSSDS SSD D ++ + ++ E S
Sbjct: 1038 DSSDSSDSSNSSDSSDSSDSSDSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1097
Query: 301 ESSD-DESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSD-SDSEVKKDKMD-V 357
+SSD +SS+SSD + S + ++ + S+ ++S SD DSSD SDS D D
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1157
Query: 358 DESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGS 408
D SDSS+ SD D + E D+S ++ + + ++ S
Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS 1208
Score = 115 bits (289), Expect = 3e-25
Identities = 101/386 (26%), Positives = 165/386 (42%), Gaps = 34/386 (8%)
Query: 68 SSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDE-DSSDEEEEVIAKKP 126
SSD DSS + + +S + + + + + SS SSD DSSD + +K
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 127 TKVVVPKKEESSSDEDSSSDEDSSSESD--------DEKPAAKVAVPAKKAPAKNGSVTA 178
+ K E SSD DS SD S+ SD D ++ + + + + + S ++
Sbjct: 626 SS----KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSS 681
Query: 179 PAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSS-----S 233
+ + + +SS S+ DSS E S + + SS DSS S
Sbjct: 682 DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 741
Query: 234 ESEDEKPAVKVSAPSKVVPAAVKNGAADS----DSSDSDSSSDEDDDKKKP-ATKVAKKL 288
+S D + S S ++ + ++DS DSSDS +SSD +D ++ +
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801
Query: 289 PAAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSD--- 345
++ + S+SSD +SS SSD N S + ++ + S+ S SSDS D DSS+
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS-DSSDSSDSSDSDSSNRSD 860
Query: 346 -------SDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKT 398
SDS + D +S S DS+E S + D + D+S+ ++ +
Sbjct: 861 SSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS 920
Query: 399 PAAQTENEGSKTLFVGNLSFSVQRSD 424
+ +E S + N S S SD
Sbjct: 921 SNSSDSSESSNSSDNSNSSDSSNSSD 946
Score = 112 bits (280), Expect = 3e-24
Identities = 95/381 (24%), Positives = 161/381 (41%), Gaps = 31/381 (8%)
Query: 62 KVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEV 121
K K +SS D S S + + + +S N ++ + + + SS SSD DSSD
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD-SDSSDSSDSDSSDSSNS- 601
Query: 122 IAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAK 181
+SS DSS DSS SD + ++K + + +K+ S + +
Sbjct: 602 -------------SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648
Query: 182 KAQP---APSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDE 238
+ + SS+ S DSS+ + S + + + S S DSS+ SE
Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESS 708
Query: 239 KPAVKVSAPSKVVPAAVKNGAADSDSSDS-DSSSDEDDDKKKPATKVAKKLPAAAPIKKV 297
+ + S + + ++DSDSS+S DSS D ++ + ++
Sbjct: 709 DSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 298 EKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSD-SDDEDSSDSDSEVKKDKMD 356
+ S+SSD S +S + NDS ++ + ++ S SSD SD DSSDSDS D +
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Query: 357 ----------VDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENE 406
D SDSS+ SD D S+ + D+S N+ + + ++
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSS-NSSDSSDSSDSSNSSDSSDSSDSSD 887
Query: 407 GSKTLFVGNLSFSVQRSDVEN 427
+++ + S S SD ++
Sbjct: 888 SNESSNSSDSSDSSNSSDSDS 908
Score = 110 bits (276), Expect = 9e-24
Identities = 82/345 (23%), Positives = 146/345 (41%), Gaps = 25/345 (7%)
Query: 66 ESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKK 125
+SS DSSS + + + + + + + ++ + SS SSD DSSD +
Sbjct: 670 DSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS----- 724
Query: 126 PTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQP 185
+SSD DSS+ DSS +S D ++ + + + + N S ++ + +
Sbjct: 725 --------SNSNSSDSDSSNSSDSS-DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775
Query: 186 APSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVS 245
+ SS+ S+ +DSS + S + + + SSD SS S D + S
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSS--NSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 246 APSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDD 305
S N + SDSSDS SSD D + ++ + ++ + S+SSD
Sbjct: 834 DSS--------NSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885
Query: 306 ESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSED 365
S S +DS ++ + S+ ++S SD +SSDS SE + + SDSS
Sbjct: 886 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS-SESSNSSDNSNSSDSSNS 944
Query: 366 SDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKT 410
SD D + + ++S ++ + ++ + N +
Sbjct: 945 SDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSSNSSDSS 989
Score = 109 bits (273), Expect = 2e-23
Identities = 88/366 (24%), Positives = 155/366 (42%), Gaps = 22/366 (6%)
Query: 66 ESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKK 125
ESS DSS D + + +S + + + + + SS SS+ SSD + +
Sbjct: 706 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSN--SSDSSDSSDSSN 763
Query: 126 PTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQP 185
+ SSD +SSD + SS S D ++ + + + + + S ++ + +
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823
Query: 186 APSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDS-------SSESEDE 238
+ SS+S S+ DSS + S + + + + +SSD S SS+S D
Sbjct: 824 SDSSNS-SDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882
Query: 239 KPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVE 298
+ + S ++ + ++DSDSSDS +SSD D + + +
Sbjct: 883 SDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS--------NSSD 934
Query: 299 KSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVD 358
S SSD +S S + +DS ++ + + S SSDS+ DSSDS + D
Sbjct: 935 NSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSSNSSDSS----D 990
Query: 359 ESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSF 418
SDSS+ SD D ++ + ++S N+ + + ++ S + N S
Sbjct: 991 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1050
Query: 419 SVQRSD 424
S SD
Sbjct: 1051 SSDSSD 1056
Score = 108 bits (271), Expect = 3e-23
Identities = 96/375 (25%), Positives = 159/375 (41%), Gaps = 19/375 (5%)
Query: 67 SSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKP 126
S S D S+S D + + S N + + + + SS SSD DSS+ + +
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDS-SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832
Query: 127 TKVVVPKKEESSSDEDSSSDEDSSSESD-----DEKPAAKVAVPAKKAPAKNGSVTAPAK 181
+ SSD SSD DSS+ SD D ++ + + + + + S + +
Sbjct: 833 SDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESS 892
Query: 182 KAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSS--SESEDEK 239
+ + S SS S D DSS+ S + + S+S DSS S+S D
Sbjct: 893 NSSDS-SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS 951
Query: 240 PAVKVSAPSKVVPAAVKNGAADSDSSDS-DSSSDEDDDKKKPATKVAKKLPAAAPIKKVE 298
+ S S ++ + ++DS+SSDS DSS+ D ++ + ++ +
Sbjct: 952 DSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1011
Query: 299 KSESSDD----ESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDS----DSEV 350
S+SSD +SS SSD + S + ++ + S+ +S SD DSSDS DS
Sbjct: 1012 SSDSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSGSSDSSD 1071
Query: 351 KKDKMDV-DESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSK 409
D D D SDSS+ SD D + + D+S ++ + + ++ S
Sbjct: 1072 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1131
Query: 410 TLFVGNLSFSVQRSD 424
+ + S S SD
Sbjct: 1132 SSDSSDSSDSSDSSD 1146
Score = 108 bits (269), Expect = 6e-23
Identities = 91/348 (26%), Positives = 144/348 (41%), Gaps = 36/348 (10%)
Query: 66 ESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKK 125
ESS+ D+S+ + + + N + + + SS SSD +SSD +
Sbjct: 928 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDS----- 982
Query: 126 PTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQP 185
+SSD SSD SS+S D ++ + + + + N S ++ + +
Sbjct: 983 ----------SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSD 1032
Query: 186 APSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSS--SESEDEKPAVK 243
+ SS S+ DSS + S + + + S S DSS S+S D +
Sbjct: 1033 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSD 1092
Query: 244 VSAPSKVVPAAVKNGAADS-DSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSES 302
S S ++ + ++DS DSSDS SSD D + + S+S
Sbjct: 1093 SSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS--------------DSSDS 1138
Query: 303 SDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSD-SDSEVKKDKMD-VDES 360
SD SS+SSD + S + ++ + S+ +S SD DSSD SDS D D D S
Sbjct: 1139 SD--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS 1196
Query: 361 DSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGS 408
DSS SD D + D + SG + +++EGS
Sbjct: 1197 DSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGS 1244
Score = 107 bits (267), Expect = 1e-22
Identities = 88/363 (24%), Positives = 154/363 (42%), Gaps = 16/363 (4%)
Query: 68 SSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPT 127
SSD SS+ + + + + + + + + SS SSD DSS+ + + +
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSS 868
Query: 128 KVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAP 187
SSD SSD + SS S D ++ + + + + N S ++ + + +
Sbjct: 869 DSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSS-DSDSSDSSNSSDSSDSSNSSDSS 927
Query: 188 SSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAP 247
SS+ S++ +SS+ S + + + S+S DSS + + S+
Sbjct: 928 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSSNSSD 987
Query: 248 SKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDD-E 306
S + + + SDSSDS +SSD D + + ++ + S+SSD +
Sbjct: 988 S----SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS-----DSSDSSDSSD 1038
Query: 307 SSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDS----DSEVKKDKMDVDES-D 361
SS+SSD N S + ++ + S+ +S SD DSSDS DS D D ES D
Sbjct: 1039 SSDSSDSSNSSDSSDSSDSSDSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1098
Query: 362 SSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQ 421
SS+ SD D + + D+S N+ + + ++ S + + S S
Sbjct: 1099 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1158
Query: 422 RSD 424
SD
Sbjct: 1159 SSD 1161
Score = 107 bits (266), Expect = 1e-22
Identities = 88/368 (23%), Positives = 155/368 (41%), Gaps = 12/368 (3%)
Query: 66 ESSSDD-DSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDED-SSDEEEEVIA 123
+S+SD DS D+K P + NG A SSS D +SDE ++
Sbjct: 444 DSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGN 503
Query: 124 KKPTKVVVPKKEESSSD---EDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPA 180
+K +S+SD DS+ + ++ ++ +D+ + K + + + + S ++ +
Sbjct: 504 GSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDS 563
Query: 181 KKAQPAPSS-SSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEK 239
+ + SS S+ S D DSS+ D + + + +SS SS+S D K
Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK 623
Query: 240 PAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEK 299
+ S + + + SDSSDS+SS D+ ++ + ++ +
Sbjct: 624 ------SDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677
Query: 300 SESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDE 359
S SSD SS S +DS ++ + + S SSDSD DSSDS + D +
Sbjct: 678 SSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 737
Query: 360 SDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSFS 419
SDSS+ SD D ++ D+S ++ + + ++ + + + S S
Sbjct: 738 SDSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 420 VQRSDVEN 427
SD N
Sbjct: 798 SNSSDSSN 805
Score = 107 bits (266), Expect = 1e-22
Identities = 95/442 (21%), Positives = 170/442 (37%), Gaps = 27/442 (6%)
Query: 4 SSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQKV 63
+S S+ +++ ++ S K+ + + +K ++ +
Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659
Query: 64 KKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIA 123
S+S D S S D + + +S + + S+SS DSSD + +
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 719
Query: 124 KKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKA 183
+SSD DSS+ D SS+S D ++ + + + + N S ++ + +
Sbjct: 720 DSS-----DSSNSNSSDSDSSNSSD-SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773
Query: 184 QPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDS------------ 231
+ SS+ S+ +DSS + S + + + S SD S
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 232 ----SSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKK 287
SS+S D + S + N + SDSSDS +SSD D + +
Sbjct: 834 DSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSN 893
Query: 288 LPAAAPIKKVEKSESSD-DESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSD- 345
++ S+SSD SS+SSD N S + ++ + ++ +S+ SD DSSD
Sbjct: 894 SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 953
Query: 346 ---SDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQ 402
SDS D + +S S SD D ++ + D+S N+ + +
Sbjct: 954 SNSSDSSNSGDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1013
Query: 403 TENEGSKTLFVGNLSFSVQRSD 424
++ S + N S S SD
Sbjct: 1014 DSSDSSNSSDSSNSSDSSDSSD 1035
Score = 105 bits (262), Expect = 4e-22
Identities = 85/356 (23%), Positives = 144/356 (39%), Gaps = 22/356 (6%)
Query: 66 ESSSDDDSSSEDEKPAPKVAPLK----TSVKNGT-TPAKKAKPAPSSSSSDEDSSDEE-- 118
ES+ +DD++SE + + S NG + +K A+ S S+SD ++SD
Sbjct: 470 ESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGN 529
Query: 119 -----EEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKN 173
++ K + SSD +SSD SS+SD + + + + +
Sbjct: 530 GNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD 589
Query: 174 GSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSS 233
S + + + + SS S D S D +K K + +SS DS S
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS---------KSESDSSDSDSKS 640
Query: 234 ESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDS-DSSSDEDDDKKKPATKVAKKLPAAA 292
+S D + + N + SDSSDS DSSS D ++ + ++
Sbjct: 641 DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSD 700
Query: 293 PIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKK 352
E S+SSD S+SSD + S ++ ++ S SSDS D +S S+
Sbjct: 701 SSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSD 760
Query: 353 DKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGS 408
D SDSS+ SD D ++ + D+S+ ++ + + ++ S
Sbjct: 761 SSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Score = 104 bits (259), Expect = 8e-22
Identities = 92/393 (23%), Positives = 164/393 (41%), Gaps = 29/393 (7%)
Query: 67 SSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDE-DSSDEEEEVIAKK 125
+SSD SS+ + + ++ N + + + + SS SSD DSSD E +
Sbjct: 837 NSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSD 896
Query: 126 PTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQP 185
+ + S+S + SSD +SS+S D ++ + + + N S ++ + +
Sbjct: 897 SS-------DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 949
Query: 186 A--------------PSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDS 231
+ S+SS+S D +SS+ + S + + + S+S DS
Sbjct: 950 SSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1009
Query: 232 SSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDK-KKPATKVAKKLPA 290
S S+ + + + + + + SDSSDS +SSD D ++ + +
Sbjct: 1010 SDSSDSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSGSSDS 1069
Query: 291 AAPIKKVEKSESSD-DESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSD-SDS 348
+ + S+SSD +SS+SSD S + ++ + S+ +S SD DSSD SDS
Sbjct: 1070 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1129
Query: 349 EVKKDKMD----VDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTE 404
D D D SDSS+ SD D + + D+S ++ + +
Sbjct: 1130 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1189
Query: 405 NEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVD 437
++ S + N S S SD + D + D
Sbjct: 1190 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESD 1222
Score = 102 bits (255), Expect = 2e-21
Identities = 96/385 (24%), Positives = 160/385 (40%), Gaps = 33/385 (8%)
Query: 67 SSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSD-------EDSSDEEE 119
S+S D S S D + ++ + + + + SS+SSD DSSD +
Sbjct: 762 SNSSDSSDSSDSSDSSD----SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817
Query: 120 EVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDE----KPAAKVAVPAKKAPAKNGS 175
+ +SS+ DSS DSS SD + ++ + + + + N S
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Query: 176 VTAPAKKAQPA--------PSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESS 227
++ + + + S SS S D DSS+ S + + S+
Sbjct: 878 DSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 937
Query: 228 SDDS--SSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSD-SDSSSDEDDDKKKPATKV 284
S DS SS+S D + S S ++ + ++DS+SSD SDSS+ D ++
Sbjct: 938 SSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS 997
Query: 285 AKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSS 344
+ ++ + S+SSD SS SSD N S + ++ + S+ +S+ SD DSS
Sbjct: 998 SDSSDSSNSSDSSDSSDSSD--SSNSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1055
Query: 345 D----SDSEVKKDKMD-VDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTP 399
D SDS D D D SDSS+ SD D + + + D+S ++ +
Sbjct: 1056 DSSDSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1115
Query: 400 AAQTENEGSKTLFVGNLSFSVQRSD 424
+ ++ S + N S S SD
Sbjct: 1116 DSSDSSDSSDSSDSSNSSDSSDSSD 1140
Score = 102 bits (255), Expect = 2e-21
Identities = 77/349 (22%), Positives = 143/349 (40%), Gaps = 5/349 (1%)
Query: 24 SAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPAPK 83
S+ + + D S+ ++ + +SSD SS+ +
Sbjct: 900 SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 959
Query: 84 VAPLKTSVKNGTTPAKKAKPAPSSSSSDE-DSSDEEEEVIAKKPTKVVVPKKEESSSDED 142
+S + ++ + + + SS+SSD DSSD + + + SSD
Sbjct: 960 SNSGDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1019
Query: 143 SSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEED 202
+SSD +SS+S D ++ + + + N S ++ + + + SS S+ DSS+
Sbjct: 1020 NSSDSSNSSDSSDSSDSSD---SSDSSDSSNSSDSSDSSDSSDSSDSSGSSDSSDSSDSS 1076
Query: 203 EPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADS 262
+ S + + + + S S DSS S+ + + + N + S
Sbjct: 1077 DSSDSSDSSDSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1136
Query: 263 DSSDSDSSSDEDDDK-KKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPAT 321
DSSDS SSD D ++ + ++ + S+SSD S S + +DS ++
Sbjct: 1137 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS 1196
Query: 322 TTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSDEED 370
+ + S SSDS + + +SDS+ K + + SDS DS+ D
Sbjct: 1197 DSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSD 1245
Score = 100 bits (248), Expect = 2e-20
Identities = 96/414 (23%), Positives = 162/414 (38%), Gaps = 46/414 (11%)
Query: 22 PKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPA 81
P S+ ++ + E ++ + A + + K+ K + DD S+ D +
Sbjct: 465 PNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNS 524
Query: 82 PKVAPLKTSVKNGTTPAKKAKPAPSSS-SSDEDSSDEEEEVIAKKPTKVVVPKKEESSSD 140
+ NG K+ S SSD DSSD + S S
Sbjct: 525 DS----NGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNS-------------SDSSDSS 567
Query: 141 EDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSS--SESEDDDS 198
+ SSD +SSS+SD + + + + + N S ++ + + + SS S+S+ D S
Sbjct: 568 DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS 627
Query: 199 SEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNG 258
E + S K + + + SSD S+S + + S+ S +
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS-------SS 680
Query: 259 AADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEEN--- 315
+ S SSDS +SSD D + + + S+SSD +SS+SSD N
Sbjct: 681 SDSSSSSDSSNSSDSSDSSDSSNSS-----------ESSDSSDSSDSDSSDSSDSSNSNS 729
Query: 316 -DSKPATTTVAKPSAVKKSASSDSDDEDSSD----SDSEVKKDKMDVDESDSSEDSDEED 370
DS + ++ + S+ +S+ SD DSSD SDS D D +S +S DS++
Sbjct: 730 SDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789
Query: 371 EKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSD 424
S + D SS + + ++ S + + S S SD
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843
Score = 88.2 bits (217), Expect = 6e-17
Identities = 93/409 (22%), Positives = 167/409 (40%), Gaps = 71/409 (17%)
Query: 38 KQVSAKKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSE--------DEKPAPKVAPLKT 89
K+V + K +E A K + K ++K SS + + + E ++K + K
Sbjct: 353 KRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKG 412
Query: 90 SVK------NGTTPAKKAKPAP----SSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSS 139
+VK N P +K++P S++ SD +S + K + ++ +S
Sbjct: 413 NVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQ-----GDDPNS 467
Query: 140 DEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSS 199
++S+ ++D++SESD+ + A NG+ + S+S++ + DS+
Sbjct: 468 SDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSN 527
Query: 200 EEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGA 259
K + K +SS +SS+S D +
Sbjct: 528 GNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD---------------------S 566
Query: 260 ADSDSSDS----DSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEEN 315
+DSDSSDS DS S + D S+SSD +SS+SS+ +
Sbjct: 567 SDSDSSDSNSSSDSDSSDSD-----------------------SSDSSDSDSSDSSNSSD 603
Query: 316 DSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTK 375
S + ++ + S+ + SDS +S SDS+ K D D + SDSS++SD D ++
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663
Query: 376 TPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSD 424
+ D+SS ++ + + ++ S + N S S SD
Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 712
Score = 87.0 bits (214), Expect = 1e-16
Identities = 66/288 (22%), Positives = 111/288 (37%), Gaps = 18/288 (6%)
Query: 67 SSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKP 126
S+S D S S D + + S + + S SS+ DSSD + +
Sbjct: 983 SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1042
Query: 127 TKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPA 186
+ SSD SSD SS+S D ++ + + + + + S ++ + + +
Sbjct: 1043 SDSSNSSDSSDSSDSSDSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1102
Query: 187 PSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSA 246
SS S+ DSS+ + S + + + S S DSS S+ + +
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1162
Query: 247 PSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSD-D 305
+ + + SDSSDS+ SSD D + S SSD
Sbjct: 1163 SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS-----------------DSSNSSDSS 1205
Query: 306 ESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKD 353
+SS+SSD +DS + + +K + S D + SDS+ D
Sbjct: 1206 DSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1253
Score = 79.7 bits (195), Expect = 2e-14
Identities = 88/375 (23%), Positives = 156/375 (41%), Gaps = 39/375 (10%)
Query: 70 DDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKV 129
D D +S+ E+ + + S + T +K S + + + E + K K
Sbjct: 318 DGDKTSKSEENSAGIPEDNGSQRIEDT--QKLNHRESKRVENRITKESETHAVGKSQDKG 375
Query: 130 VVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAK--KAPAKNGSVTAPAKKAQPA- 186
+ K SS + + + + +E ++K + + K + ++ P +K++P
Sbjct: 376 I-EIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGN 434
Query: 187 ------PSSSSESE-------DDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSS 233
S S S+ DD S + D+P++ A + SSS +S
Sbjct: 435 KVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESN--GNDDANSESDNNSSSRGDAS 492
Query: 234 ESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSD--EDDDKKKPATKVAKKLPAA 291
+ DE + SK + +D+++SDS+ + + DD+ K + K
Sbjct: 493 YNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGK-------- 544
Query: 292 APIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVK 351
KS+SSD +SS+SS+ + S + + + ++ S SSDSD DSSDSDS
Sbjct: 545 ------GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS 598
Query: 352 KDKMD-VDESDSSEDSDEEDEKSTKTPQKKVK-DVEMVDASSGKNAPKTPAAQTENEGSK 409
+ D D SDSS+ SD D +K+ K + D D+ S + + + ++ S
Sbjct: 599 SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658
Query: 410 TLFVGNLSFSVQRSD 424
+ N S S SD
Sbjct: 659 SSNSSNSSDSSDSSD 673
Score = 43.5 bits (101), Expect = 0.002
Identities = 51/213 (23%), Positives = 73/213 (33%), Gaps = 71/213 (33%)
Query: 66 ESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSD-EDSSDEEEEVIAK 124
+SS DSS + + + + + + + + SS SSD DSSD +
Sbjct: 1110 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD----- 1164
Query: 125 KPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQ 184
SSD SSD SS+S D ++
Sbjct: 1165 -------------SSDSSDSSDSSDSSDSSDSNESS------------------------ 1187
Query: 185 PAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKV 244
SS S+ DSS + S + S S DS+S+S DE +
Sbjct: 1188 ---DSSDSSDSSDSSNSSDSS------------------DSSDSSDSTSDSNDESDSQSK 1226
Query: 245 SAPSKVVPAAVKNGA-ADSDSSDSDSSSDEDDD 276
S NG+ +DSDS SDS+ DD
Sbjct: 1227 SGNGN------NNGSDSDSDSEGSDSNHSTSDD 1253
Score = 38.9 bits (89), Expect = 0.044
Identities = 38/174 (21%), Positives = 60/174 (33%), Gaps = 26/174 (14%)
Query: 66 ESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDE-DSSDEEEEVIAK 124
+SS DSS + + + N + + + + SS SSD DSSD + +
Sbjct: 1104 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1163
Query: 125 KPTKVVVPKKEESSSDE-DSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKA 183
+ SSD DS+ DSS SD + +
Sbjct: 1164 DSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS------------------------SDSS 1199
Query: 184 QPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESED 237
+ SS S D +S+ ++ S Q K + SD + S S+D
Sbjct: 1200 NSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1253
Score = 35.4 bits (80), Expect = 0.48
Identities = 82/445 (18%), Positives = 155/445 (34%), Gaps = 74/445 (16%)
Query: 189 SSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPS 248
S++ D +++ + ++VAV VQ+ + + ++S+++EDE
Sbjct: 152 SNTNGNTDKNTQNGDVGDAGHNEDVAV---VQEDGPQVAGSNNSTDNEDE---------- 198
Query: 249 KVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESS 308
++ + +N S+ + +S K+ TK A+ P ++ S+ S +
Sbjct: 199 -IIENSCRNEGNTSEITPQINS-------KRNGTKEAEVTPGTGEDAGLDNSDGSPSGNG 250
Query: 309 ESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSDE 368
DE+ S A K +S++S ++ D E D SDS E D
Sbjct: 251 ADEDEDEGSGDDEDEEAGNG---KDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDP 307
Query: 369 E-----------------DEKSTKTPQ----KKVKDVEMVDASSGKNAPKTPAAQTENEG 407
E +E S P+ ++++D + ++ K ++E
Sbjct: 308 EGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHA 367
Query: 408 SKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATDEDGRFKGFGHVEFATAAAAQSALE 467
+ S N K+ G+ + + + G G G+V+ +
Sbjct: 368 VGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVK-----TQGEVVN 422
Query: 468 YNGSELLQRPVRLDLARERGAYTPNSGAANNSF-QKGGRGQSQTVFVRGFDKFQGEDDIK 526
G P G+ + + G + F K +G D+ G DD
Sbjct: 423 IEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDP----NSSDESNGNDDAN 478
Query: 527 SSLQEHFGSCGEITRIS-VPKDFESGNVKGFAYLDFSDTNSVNKALELHDSDLGGFTLAV 585
S + S G+ + S KD +G+ A D SD+ S + ++SD G
Sbjct: 479 SESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTS-----DTNNSDSNG----- 528
Query: 586 DEAKPRDNQGSGGRSGGGRSGGGRG 610
G+ G +S G+G
Sbjct: 529 --------NGNNGNDDNDKSDSGKG 545
>SR40_YEAST (P32583) Suppressor protein SRP40
Length = 406
Score = 120 bits (301), Expect = 1e-26
Identities = 107/377 (28%), Positives = 162/377 (42%), Gaps = 70/377 (18%)
Query: 40 VSAKKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAK 99
+++KK K+ EV KE ++++ SSS SSS + +S +G + +
Sbjct: 1 MASKKIKVDEVPKLSVKEKEIEEKSSSSSSSSSSSSSSSSSSSS-----SSSSSGESSSS 55
Query: 100 KAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDED---------SS 150
+ + SSSS DSSD E + + SSSD +SSS+ D SS
Sbjct: 56 SSSSSSSSSSDSSDSSDSESSSSSSSSSS-----SSSSSSDSESSSESDSSSSGSSSSSS 110
Query: 151 SESDDEKPAAKVAVPAKKAPAKNGSVTA-PAKKAQPAPSSSSESEDDDSSEEDEPSAKQP 209
S SD+ ++ KK ++ + A KKA+ P SSS SE S S+
Sbjct: 111 SSSDESSSESESEDETKKRARESDNEDAKETKKAKTEPESSSSSESSSSG-----SSSSS 165
Query: 210 KKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDS 269
+ E + SSS DS S+SE + + S+ S + ++DSDSS SDS
Sbjct: 166 ESESGSESDSDSSSSSSSSSDSESDSESDSQSSSSSSSS--------DSSSDSDSSSSDS 217
Query: 270 SSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSA 329
SSD S+SS SS SSD ++DS ++ + + S+
Sbjct: 218 SSD---------------------------SDSSSSSSSSSSDSDSDSDSSSDSDSSGSS 250
Query: 330 VKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDA 389
S+SSDS ++S+ SDS +SDS DS E TK E A
Sbjct: 251 -DSSSSSDSSSDESTSSDS---------SDSDSDSDSGSSSELETKEATADESKAEETPA 300
Query: 390 SSGKNAPKTPAAQTENE 406
SS ++ P ++ + N+
Sbjct: 301 SSNESTPSASSSSSANK 317
Score = 89.4 bits (220), Expect = 3e-17
Identities = 89/419 (21%), Positives = 173/419 (41%), Gaps = 41/419 (9%)
Query: 3 KSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQK 62
KSS S++ +++ +++ S+ + ++ S+ ++ +
Sbjct: 24 KSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSSSSSSDSSDSSDSESSSSSSSSS 83
Query: 63 VKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVI 122
SSSD +SSSE + + + +S + ++ +++ + + D+ D +E
Sbjct: 84 SSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESESEDETKKRARESDNEDAKETKK 143
Query: 123 AKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKK 182
AK + E SSS SSS+ +S SESD + ++ + ++ +++ S +
Sbjct: 144 AKTEPESS-SSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSESDSESDS------Q 196
Query: 183 AQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAV 242
+ + SSS S D DSS D S + + +SSSD SS S D +
Sbjct: 197 SSSSSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDSSGSSDSSSSS 256
Query: 243 KVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSES 302
S+ + + SDSSDSDS SD ++E E+
Sbjct: 257 DSSS----------DESTSSDSSDSDSDSDSGSS------------------SELETKEA 288
Query: 303 SDDES--SESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDES 360
+ DES E+ N+S P+ ++ + + + A +D E S V + K++ +
Sbjct: 289 TADESKAEETPASSNESTPSASSSSSANKLNIPAGTDEIKEGQRKHFSRVDRSKINFEAW 348
Query: 361 DSSEDSDEEDEKS-TKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSF 418
+ ++++ + + + +K+ V D + KN K + + GS TL G+ F
Sbjct: 349 ELTDNTYKGAAGTWGEKANEKLGRVRGKDFTKNKNKMKRGSYR---GGSITLESGSYKF 404
Score = 86.7 bits (213), Expect = 2e-16
Identities = 86/305 (28%), Positives = 131/305 (42%), Gaps = 60/305 (19%)
Query: 122 IAKKPTKV-VVPK---KEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVT 177
+A K KV VPK KE+ ++ SSS SSS S + + + + S +
Sbjct: 1 MASKKIKVDEVPKLSVKEKEIEEKSSSSSSSSSSSSS-----------SSSSSSSSSSSS 49
Query: 178 APAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESED 237
+ + + SSSS S+ DSS+ + S+ SSS SSS S+
Sbjct: 50 GESSSSSSSSSSSSSSDSSDSSDSESSSSSS-----------------SSSSSSSSSSDS 92
Query: 238 EKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDE---DDDKKKPA----------TKV 284
E + S+ S G++ S SS SD SS E +D+ KK A TK
Sbjct: 93 ESSSESDSSSS---------GSSSSSSSSSDESSSESESEDETKKRARESDNEDAKETKK 143
Query: 285 AKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSAS-SDSDDEDS 343
AK P ++ SESS SS SS+ E+ S+ + + + S+ S S S+SD + S
Sbjct: 144 AKTEPESS-----SSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSESDSESDSQSS 198
Query: 344 SDSDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQT 403
S S S D SDSS DSD S+ + D+ S ++ + ++ +
Sbjct: 199 SSSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDSSGSSDSSSSSDS 258
Query: 404 ENEGS 408
++ S
Sbjct: 259 SSDES 263
Score = 67.8 bits (164), Expect = 9e-11
Identities = 49/210 (23%), Positives = 90/210 (42%), Gaps = 14/210 (6%)
Query: 205 SAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDS 264
++K+ K + K +V++K+ E S SSS S + S+ S + ++ S S
Sbjct: 2 ASKKIKVDEVPKLSVKEKEIEEKSSSSSSSSSSSSSSSSSSSSSSSSSGESSSSSSSSSS 61
Query: 265 SDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPATTTV 324
S S SSD D + ++ + S SSD ESS SD + ++++
Sbjct: 62 SSSSDSSDSSDSESSSSSSSSSS----------SSSSSSDSESSSESDSSSSGSSSSSSS 111
Query: 325 AKPSAVKKSASSDSDDEDSSDSDS----EVKKDKMDVDESDSSEDSDEEDEKSTKTPQKK 380
+ + +S S D + + +SD+ E KK K + + S SSE S S+++
Sbjct: 112 SSDESSSESESEDETKKRARESDNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGS 171
Query: 381 VKDVEMVDASSGKNAPKTPAAQTENEGSKT 410
D + +SS + ++ + S +
Sbjct: 172 ESDSDSSSSSSSSSDSESDSESDSQSSSSS 201
>DSPP_MOUSE (P97399) Dentin sialophosphoprotein precursor (Dentin
matrix protein-3) (DMP-3) [Contains: Dentin
phosphoprotein (Dentin phosphophoryn) (DPP); Dentin
sialoprotein (DSP)]
Length = 934
Score = 114 bits (284), Expect = 1e-24
Identities = 89/359 (24%), Positives = 146/359 (39%), Gaps = 23/359 (6%)
Query: 66 ESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKK 125
ES SD SS+D + + S + + S S+S DSSD +
Sbjct: 543 ESKSDSSDSSDDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNSSSDSSDSSGSSDSSD 602
Query: 126 PTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQP 185
+ SSD SSD SS+S D ++ + + + + + S + + +
Sbjct: 603 SSDTCDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSSSSDSSDSSSCSDSSDSSD 662
Query: 186 APSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVS 245
+ SS S+ DSS D S+ + SSS DSS S+ +
Sbjct: 663 SSDSSDSSDSSDSSSSDSSSSSNSSDS-------SDSSDSSSSSDSSDSSDSSDSSDSSG 715
Query: 246 APSKVVPAAVKNGAADSDSSDSDSSSDEDDDK-KKPATKVAKKLPAAAPIKKVEKSESSD 304
+ +A + ++ SDSSDS SSSD D ++ ++ ++ + S+SSD
Sbjct: 716 SSDSSDSSASSDSSSSSDSSDSSSSSDSSDSSDSSDSSDSSESSDSSNSSDSSDSSDSSD 775
Query: 305 D-------ESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDS-------DSEV 350
+SS+SSD N S + ++ + S+ ++S SD DSSDS DS
Sbjct: 776 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 835
Query: 351 KKDKMDV-DESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGS 408
D D D SDSS+ SD D + + D+S N+ + + +++ S
Sbjct: 836 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSDSKDSSS 894
Score = 112 bits (279), Expect = 4e-24
Identities = 104/416 (25%), Positives = 173/416 (41%), Gaps = 20/416 (4%)
Query: 22 PKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPA 81
PKS+ ++ + E + + SA + A+ E+ +S + +D SS+D
Sbjct: 454 PKSSDESNGSDESDTNSE-SANESGSRGDASYTSDESSDDDNDSDSHAGEDDSSDDSSGD 512
Query: 82 PKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEES-SSD 140
S NG ++ S SS ++SSD E + + + + S SSD
Sbjct: 513 GD------SDSNGDGDSESEDKDESDSSDHDNSSDSESKSDSSDSSDDSSDSSDSSDSSD 566
Query: 141 EDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSE 200
SSD SS+S D + + + + + + S ++ + + SS S+ DSS+
Sbjct: 567 SSDSSDSSDSSDSSDSSDSNSSSDSSDSSGSSDSSDSSDTCDSSDSSDSSDSSDSSDSSD 626
Query: 201 EDEPSAKQPKKEVAVKPAVQKKKEESSSDDSS--SESEDEKPAVKVSAPSKVVPAAVKNG 258
+ S + + + + SS DSS S+S D + S S ++ N
Sbjct: 627 SSDSSDSSDSSDSSDSSSSSDSSDSSSCSDSSDSSDSSDSSDSSDSSDSSSSDSSSSSNS 686
Query: 259 AADSDSSDSDSSSDEDDDK----KKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEE 314
+ SDSSDS SSSD D ++ + ++A S+SSD SS S +
Sbjct: 687 SDSSDSSDSSSSSDSSDSSDSSDSSDSSGSSDSSDSSASSDSSSSSDSSDSSSSSDSSDS 746
Query: 315 NDSKPATTTVAKPSAVKKSASSDSDDE-DSSDS-DSEVKKDKMDV----DESDSSEDSDE 368
+DS ++ + + S SSDS D DSSDS DS D D D SDSS+ SD
Sbjct: 747 SDSSDSSDSSESSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 806
Query: 369 EDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSD 424
D ++ + D+S ++ + + ++ S + + S S SD
Sbjct: 807 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 862
Score = 109 bits (273), Expect = 2e-23
Identities = 93/371 (25%), Positives = 160/371 (43%), Gaps = 15/371 (4%)
Query: 66 ESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKK 125
+S+ D DS SED+ + +S + ++ ++ + SS DSSD + +
Sbjct: 516 DSNGDGDSESEDKDESD------SSDHDNSSDSESKSDSSDSSDDSSDSSDSSDSSDSSD 569
Query: 126 PTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQP 185
+ SSD +SSSD SS S D ++ + + + + S ++ + +
Sbjct: 570 SSDSSDSSDSSDSSDSNSSSDSSDSSGSSDSSDSSDTCDSSDSSDSSDSSDSSDSSDSSD 629
Query: 186 APSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEES-SSDDSSSESEDEKPAVKV 244
+ SS S+ DSS + S + + + S SSD SSS+S +
Sbjct: 630 SSDSSDSSDSSDSSSSSDSSDSSSCSDSSDSSDSSDSSDSSDSSDSSSSDSSSSSNSSDS 689
Query: 245 SAPSKVVPAAVKNGAAD-SDSSDSDSSSDEDDDK-KKPATKVAKKLPAAAPIKKVEKSES 302
S S ++ + ++D SDSSDS SSD D ++ + +++ + S+S
Sbjct: 690 SDSSDSSSSSDSSDSSDSSDSSDSSGSSDSSDSSASSDSSSSSDSSDSSSSSDSSDSSDS 749
Query: 303 SD-DESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSD-SDSEVKKDKMDVDE- 359
SD +SSESSD N S + ++ + S+ +S SD DSS+ SDS D D +
Sbjct: 750 SDSSDSSESSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 809
Query: 360 ---SDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNL 416
SDSS+ SD D + + D+S ++ + + ++ S + +
Sbjct: 810 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 869
Query: 417 SFSVQRSDVEN 427
S S SD N
Sbjct: 870 SDSSDSSDSSN 880
Score = 85.9 bits (211), Expect = 3e-16
Identities = 99/402 (24%), Positives = 169/402 (41%), Gaps = 37/402 (9%)
Query: 21 APKSAKKAKRAAEDEVEKQVSAKKQKIA---EVAAKQKKETKLQKVKKESSSDDDSSSE- 76
+PK + A+ + E S K Q E K K ++ K S S D + +
Sbjct: 336 SPKDTRDAEGGIISQSEACPSGKSQDQGIETEGPNKGNKSIITKESGKLSGSKDSNGHQG 395
Query: 77 ---DEKPAPKVA----PLKTSVKNGTTPAKKAKPAPSSSSSD-EDSSDEEEEVIAKKPTK 128
D++ +PK P T+ K+ SSS+SD DS + ++E + K
Sbjct: 396 VELDKRNSPKQGESDKPQGTAEKSAAHSNLGHSRIGSSSNSDGHDSYEFDDESMQGDDPK 455
Query: 129 VVVPKKEESSSDEDSSSDE-DSSSESDDEKPA-AKVAVPAKKAPAKNGSVTAPAKKAQPA 186
SSDE + SDE D++SES +E + + + ++ + + A + +
Sbjct: 456 ---------SSDESNGSDESDTNSESANESGSRGDASYTSDESSDDDNDSDSHAGEDDSS 506
Query: 187 PSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSA 246
SS + + D + + D S + + + + + +S S DSS +S D + S
Sbjct: 507 DDSSGDGDSDSNGDGDSESEDKDESDSSDHDNSSDSESKSDSSDSSDDSSDSSDSSDSSD 566
Query: 247 PSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDE 306
S ++ + + SDSSDS+SSSD D + + + S+SSD
Sbjct: 567 SSDSSDSS--DSSDSSDSSDSNSSSDSSDSSGSSDSSDSSDT--------CDSSDSSDSS 616
Query: 307 SSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDS 366
S S + +DS ++ + + S+SSDS D SS SDS D D SDSS+ S
Sbjct: 617 DSSDSSDSSDSSDSSDSSDSSDSSDSSSSSDSSDS-SSCSDSSDSSDSSD--SSDSSDSS 673
Query: 367 DEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGS 408
D S+ + + D+SS ++ + + ++ S
Sbjct: 674 DSSSSDSSSSSNSS-DSSDSSDSSSSSDSSDSSDSSDSSDSS 714
Score = 82.0 bits (201), Expect = 5e-15
Identities = 74/366 (20%), Positives = 139/366 (37%), Gaps = 71/366 (19%)
Query: 5 SKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQKVK 64
S S++ +++ + + S + D + S+ + + ++
Sbjct: 639 SSDSSSSSDSSDSSSCSDSSDSSDSSDSSDSSDSSDSSSSDSSSSSNSSDSSDSSDSSSS 698
Query: 65 KESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSD-EDSSDEEEEVIA 123
+SS DSS + + ++ + ++ + + + SS SSD DSSD +
Sbjct: 699 SDSSDSSDSSDSSDSSGSSDSSDSSASSDSSSSSDSSDSSSSSDSSDSSDSSDSSD---- 754
Query: 124 KKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKA 183
SSD +SSD SS+S D ++ + + + + N S ++ + +
Sbjct: 755 -----------SSESSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 803
Query: 184 QPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVK 243
+ SS+ S+ DSS+ + S + + + S S DSS S+
Sbjct: 804 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD------- 856
Query: 244 VSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESS 303
SDSSDS SSD D S S
Sbjct: 857 -----------------SSDSSDSSDSSDSSD------------------------SSDS 875
Query: 304 DDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSS 363
D S+ S ++DSK +++ + + + +SDS+ + +SDSDS D + SDS+
Sbjct: 876 SDSSNSSDSSDSDSKDSSSDSSDGDSKSGNGNSDSNSDSNSDSDS-------DSEGSDSN 928
Query: 364 EDSDEE 369
+ ++
Sbjct: 929 HSTSDD 934
Score = 79.0 bits (193), Expect = 4e-14
Identities = 66/255 (25%), Positives = 109/255 (41%), Gaps = 24/255 (9%)
Query: 67 SSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKP 126
S S D SSS D + + +S +G++ + + A S SSS DSSD +
Sbjct: 690 SDSSDSSSSSDSSDSSDSSD--SSDSSGSSDSSDSS-ASSDSSSSSDSSDSSSSSDSSDS 746
Query: 127 TKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPA 186
+ SSD +SSD SS+S D ++ + + + + N S ++ + + +
Sbjct: 747 SDSSDSSDSSESSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 806
Query: 187 PSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSS--SESEDEKPAVKV 244
SS+ S+ DSS+ + S + + + S S DSS S+S D +
Sbjct: 807 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 866
Query: 245 SAPSKVVPAAVKNGAADSDSSDS-DSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESS 303
S S ++ + ++DS SDS DSSSD D K + +S
Sbjct: 867 SDSSDSSDSSDSSNSSDSSDSDSKDSSSDSSDGDSKSG------------------NGNS 908
Query: 304 DDESSESSDEENDSK 318
D S +SD ++DS+
Sbjct: 909 DSNSDSNSDSDSDSE 923
Score = 78.6 bits (192), Expect = 5e-14
Identities = 60/256 (23%), Positives = 101/256 (39%), Gaps = 19/256 (7%)
Query: 67 SSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKP 126
SSS D S S D + + S + + + S SSS DSSD + +
Sbjct: 696 SSSSDSSDSSDSSDSSDSSGSSDSSDSSASSDSSSSSDSSDSSSSSDSSDSSDSSDSSDS 755
Query: 127 TKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPA 186
++ SSD SSD SS+S D ++ + + + + + S ++ + + +
Sbjct: 756 SESSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 815
Query: 187 PSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVKVSA 246
SS S+ DSS+ + S + + +SS SS+S D + S
Sbjct: 816 SDSSDSSDSSDSSDSSDSSDSSDSSD----SSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 871
Query: 247 PSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDE 306
S ++ + ++DSDS DS S S + D K S S +
Sbjct: 872 SSDSSDSSNSSDSSDSDSKDSSSDSSDGDSKSGNGN---------------SDSNSDSNS 916
Query: 307 SSESSDEENDSKPATT 322
S+S E +DS +T+
Sbjct: 917 DSDSDSEGSDSNHSTS 932
Score = 67.8 bits (164), Expect = 9e-11
Identities = 56/273 (20%), Positives = 102/273 (36%), Gaps = 14/273 (5%)
Query: 4 SSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQKV 63
SS S++ ++ ++ S+ + D + S+ ++ +A +
Sbjct: 676 SSSDSSSSSNSSDSSDSSDSSSSSDSSDSSDSSDSSDSSGSSDSSDSSASSDSSSSSDSS 735
Query: 64 KKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIA 123
SSSD SS+ + +S + ++ + + S SS DSSD + +
Sbjct: 736 DSSSSSDSSDSSDSSDSSDSSESSDSSNSSDSSDSSDS----SDSSDSSDSSDSSDSSDS 791
Query: 124 KKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKA 183
+ SSD +SSD SS+S D ++ + + + + + S ++ + +
Sbjct: 792 SNSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 851
Query: 184 QPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSESEDEKPAVK 243
+ SS S+ DSS+ + S +SS DS S D
Sbjct: 852 SDSSDSSDSSDSSDSSDSSDSSDSSD----------SSNSSDSSDSDSKDSSSDSSDGDS 901
Query: 244 VSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDD 276
S + N +DSDS SDS+ DD
Sbjct: 902 KSGNGNSDSNSDSNSDSDSDSEGSDSNHSTSDD 934
Score = 60.5 bits (145), Expect = 1e-08
Identities = 78/349 (22%), Positives = 138/349 (39%), Gaps = 36/349 (10%)
Query: 107 SSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPA 166
SS S ED +E+E ++SS+E+ + DS+ + D++ + P
Sbjct: 290 SSVSTEDDDSKEQEGFPNG-------HNGDNSSEENGVEEGDSTQATQDKEKLS----PK 338
Query: 167 KKAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPS--AKQPKKEVAVKPAVQKKKE 224
A+ G ++ +A P+ S + + + + S K+ K K + +
Sbjct: 339 DTRDAEGGIISQ--SEACPSGKSQDQGIETEGPNKGNKSIITKESGKLSGSKDSNGHQGV 396
Query: 225 ESSSDDSSSESEDEKP---AVKVSAPSKVVPAAVKNGAADSDSSDS----DSSSDEDDDK 277
E +S + E +KP A K +A S + + + +++SD DS D S DD K
Sbjct: 397 ELDKRNSPKQGESDKPQGTAEKSAAHSNLGHSRI-GSSSNSDGHDSYEFDDESMQGDDPK 455
Query: 278 KKPATKVAKKLPAAAPIKKVEKSESSDDES---SESSDEENDSKPATTTVAKPSAVKKSA 334
+ + + + + +S S D S ESSD++NDS A + +
Sbjct: 456 SSDESNGSDESDTNS--ESANESGSRGDASYTSDESSDDDNDSDS--------HAGEDDS 505
Query: 335 SSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKN 394
S DS + SDS+ + + D DESDSS+ + D +S D SS +
Sbjct: 506 SDDSSGDGDSDSNGDGDSESEDKDESDSSDHDNSSDSESKSDSSDSSDDSSDSSDSSDSS 565
Query: 395 APKTPAAQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATD 443
+ +++ S N S S + D + D ++D
Sbjct: 566 DSSDSSDSSDSSDSSDSSDSNSSSDSSDSSGSSDSSDSSDTCDSSDSSD 614
Score = 59.7 bits (143), Expect = 2e-08
Identities = 90/418 (21%), Positives = 155/418 (36%), Gaps = 65/418 (15%)
Query: 65 KESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEVIAK 124
K + D S + D + P + S+KN T +A S ++ E + E
Sbjct: 162 KSGGASDVSQNGDATLVQENEPPEASIKNSTN--HEAGIHGSGVATHETTPQREGLGSEN 219
Query: 125 KPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQ 184
+ T+V E++ D+ S + E D++ + + A A +G + K Q
Sbjct: 220 QGTEVTPSIGEDAGLDDTDGSPSGNGVEEDEDTGSGD----GEGAEAGDGRESHDGTKGQ 275
Query: 185 PAPS----------SSSESEDDDSSEE---------------------DEPSAKQPKKEV 213
S SS +EDDDS E+ D A Q K+++
Sbjct: 276 GGQSHGGNTDHRGQSSVSTEDDDSKEQEGFPNGHNGDNSSEENGVEEGDSTQATQDKEKL 335
Query: 214 AVKPAVQKKKEESSSDDSSSESEDEKPAVKVSAPSKVVPAAV-KNGAADSDSSDSDSSSD 272
+ K + S ++ + + ++ P+K + + K S S DS+
Sbjct: 336 SPKDTRDAEGGIISQSEACPSGKSQDQGIETEGPNKGNKSIITKESGKLSGSKDSNGHQG 395
Query: 273 EDDDKKKPATKVAKKLPAAAPIK----------KVEKSESSD--------DESSE----- 309
+ DK+ + P K ++ S +SD DES +
Sbjct: 396 VELDKRNSPKQGESDKPQGTAEKSAAHSNLGHSRIGSSSNSDGHDSYEFDDESMQGDDPK 455
Query: 310 SSDEENDSKPATTTV--AKPSAVKKSASSDSDDEDSSDSDSEVKKDKMD-VDESDSSEDS 366
SSDE N S + T A S + AS SD+ D+DS+ + D D+S DS
Sbjct: 456 SSDESNGSDESDTNSESANESGSRGDASYTSDESSDDDNDSDSHAGEDDSSDDSSGDGDS 515
Query: 367 DEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSD 424
D + +++ K D D SS + K+ ++ + ++ S + + S S SD
Sbjct: 516 DSNGDGDSESEDKDESDSSDHDNSSDSES-KSDSSDSSDDSSDSSDSSDSSDSSDSSD 572
Score = 32.0 bits (71), Expect = 5.3
Identities = 31/107 (28%), Positives = 45/107 (41%), Gaps = 19/107 (17%)
Query: 574 HDSDLGGFTLAVDEAKPR------DNQGS------GGRSG-----GGRSGGGRGGRFDSG 616
H++ + G +A E P+ +NQG+ G +G G SG G D+G
Sbjct: 194 HEAGIHGSGVATHETTPQREGLGSENQGTEVTPSIGEDAGLDDTDGSPSGNGVEEDEDTG 253
Query: 617 RGGGRGRFGSGGRGGDRGGRGGRGGGGRGGRGTPLRAEGKKTTFADE 663
G G G GR G + G+GG GG T R + +T D+
Sbjct: 254 SGDGEGAEAGDGRESHDGTK-GQGGQSHGG-NTDHRGQSSVSTEDDD 298
>NFH_MOUSE (P19246) Neurofilament triplet H protein (200 kDa
neurofilament protein) (Neurofilament heavy polypeptide)
(NF-H)
Length = 1087
Score = 112 bits (280), Expect = 3e-24
Identities = 107/430 (24%), Positives = 187/430 (42%), Gaps = 30/430 (6%)
Query: 3 KSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQK 62
KS ++ + EA +P A KS +AK AE + + + + + AK E K
Sbjct: 645 KSPSEAKSPAEAKSPAEA--KSPAEAKSPAEVKSPGEAKSPAEPKSPAEAKSPAEVK-SP 701
Query: 63 VKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGT-TPAKKAKPAPSSSSSDEDSSDEEEEV 121
+ +S ++ S E + PA +P + +P + P + S ++ S E +
Sbjct: 702 AEAKSPAEVKSPGEAKSPAAVKSPAEAKSPAAVKSPGEAKSPGEAKSPAEAKSPAEAKSP 761
Query: 122 I-AKKPTKVVVPKKEESSSDEDSSSDEDSSSE-SDDEKPAAKVAVPAK-KAPAKNGSVTA 178
I K P K P KE + S ++ S E + S +D KP A+ P K K+P K G+
Sbjct: 762 IEVKSPEKAKTPVKEGAKSPAEAKSPEKAKSPVKEDIKPPAEAKSPEKAKSPVKEGA--K 819
Query: 179 PAKKAQPAPSSSSESEDDDSSEEDEPS-------AKQPKKEVAVKPAVQKKKEESSSDDS 231
P +KA+P S E++ E P+ K P KE A P +K+E +S+
Sbjct: 820 PPEKAKPLDVKSPEAQTPVQEEATVPTDIRPPEQVKSPAKEKAKSP---EKEEAKTSEKV 876
Query: 232 SSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKK---KPATKVAKKL 288
+ + E+ K VK +K P V+ S +D+ K KP + K+
Sbjct: 877 APKKEEVKSPVKEEVKAKEPPKKVEEEKTLPTPKTEAKESKKDEAPKEAPKPKVEEKKET 936
Query: 289 PAAAP---IKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSD 345
P P + +K E+ + + + +S+EE +K AKP ++ ++++D + +
Sbjct: 937 PTEKPKDSTAEAKKEEAGEKKKAVASEEETPAKLGVKEEAKPKEKTETTKTEAEDTKAKE 996
Query: 346 SDSEVKKDKMDVDESDSS-EDSDEEDEKSTKT--PQKKVKDVEMV--DASSGKNAPKTPA 400
+ +K +E ++ E D ++EK+T++ P++K K V D S P P
Sbjct: 997 PSKPTETEKPKKEEMPAAPEKKDTKEEKTTESRKPEEKPKMEAKVKEDDKSLSKEPSKPK 1056
Query: 401 AQTENEGSKT 410
+ + S T
Sbjct: 1057 TEKAEKSSST 1066
Score = 102 bits (254), Expect = 3e-21
Identities = 94/394 (23%), Positives = 165/394 (41%), Gaps = 43/394 (10%)
Query: 3 KSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQK 62
KS + EA +P A K+ A+ E + A+ + EV + +K +T +++
Sbjct: 717 KSPAAVKSPAEAKSPAAVKSPGEAKSPGEAKSPAEAKSPAEAKSPIEVKSPEKAKTPVKE 776
Query: 63 VKK---ESSSDDDSSS---EDEKP---APKVAPLKTSVKNGTTPAKKAKPAPSSSSSDED 113
K E+ S + + S ED KP A K+ VK G P +KAKP S +
Sbjct: 777 GAKSPAEAKSPEKAKSPVKEDIKPPAEAKSPEKAKSPVKEGAKPPEKAKPLDVKSPEAQT 836
Query: 114 SSDEEEEVIA--KKPTKVVVPKKEESSSDE--DSSSDEDSSSESDDEKPAAKVAVPAKKA 169
EE V + P +V P KE++ S E ++ + E + + ++ K K V AK+
Sbjct: 837 PVQEEATVPTDIRPPEQVKSPAKEKAKSPEKEEAKTSEKVAPKKEEVKSPVKEEVKAKEP 896
Query: 170 PAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSD 229
P K +K P P + ++ S++DE + PK +V K +K + S+
Sbjct: 897 PKK-----VEEEKTLPTPKTEAKE-----SKKDEAPKEAPKPKVEEKKETPTEKPKDSTA 946
Query: 230 DSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLP 289
++ E EK S VK A + +++ + ED K+P+
Sbjct: 947 EAKKEEAGEKKKAVASEEETPAKLGVKEEAKPKEKTETTKTEAEDTKAKEPS-------- 998
Query: 290 AAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSE 349
K ++E E ++ E+ D+K TT ++ K + ++D S S
Sbjct: 999 ------KPTETEKPKKEEMPAAPEKKDTKEEKTTESRKPEEKPKMEAKVKEDDKSLSKEP 1052
Query: 350 VKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKD 383
K +++ +E S D+K ++ P+K +D
Sbjct: 1053 SK------PKTEKAEKSSSTDQKESQPPEKTTED 1080
Score = 96.7 bits (239), Expect = 2e-19
Identities = 97/414 (23%), Positives = 173/414 (41%), Gaps = 16/414 (3%)
Query: 3 KSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQK 62
KS ++ + EA +P A KS +AK AE + V + + + AK E K
Sbjct: 603 KSPAEAKSPAEAKSPAEA--KSPAEAKSPAEAKSPATVKSPGEAKSPSEAKSPAEAK-SP 659
Query: 63 VKKESSSDDDSSSEDEKPAPKVAPLKT-SVKNGTTPAKKAKPAPSSSSSDEDSSDEEEEV 121
+ +S ++ S +E + P +P + S +PA+ PA + S ++ S E +
Sbjct: 660 AEAKSPAEAKSPAEVKSPGEAKSPAEPKSPAEAKSPAEVKSPAEAKSPAEVKSPGEAKSP 719
Query: 122 IA-KKPTKVVVPKKEESSSDEDSSSDEDSSSESD---DEKPAAKVAVPAK-KAPAKNGSV 176
A K P + P +S + S + S +E+ + K +V P K K P K G+
Sbjct: 720 AAVKSPAEAKSPAAVKSPGEAKSPGEAKSPAEAKSPAEAKSPIEVKSPEKAKTPVKEGAK 779
Query: 177 T-APAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDDSSSES 235
+ A AK + A S E + + AK P KE A KP + K + S ++ +
Sbjct: 780 SPAEAKSPEKAKSPVKEDIKPPAEAKSPEKAKSPVKEGA-KPPEKAKPLDVKSPEAQTPV 838
Query: 236 EDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIK 295
++E P + V + K A + ++ +S K++ + V +++ A P K
Sbjct: 839 QEEATVPTDIRPPEQVKSPAKEKAKSPEKEEAKTSEKVAPKKEEVKSPVKEEVKAKEPPK 898
Query: 296 KVEKSESSDDESSESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKM 355
KVE+ ++ +E+ + + D P KP +K ++ E DS +E KK++
Sbjct: 899 KVEEEKTLPTPKTEAKESKKDEAP--KEAPKPKVEEK---KETPTEKPKDSTAEAKKEEA 953
Query: 356 DVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPAAQTENEGSK 409
+ + + + + K K + E + K P+ TE E K
Sbjct: 954 GEKKKAVASEEETPAKLGVKEEAKPKEKTETTKTEAEDTKAKEPSKPTETEKPK 1007
Score = 96.3 bits (238), Expect = 2e-19
Identities = 113/438 (25%), Positives = 195/438 (43%), Gaps = 41/438 (9%)
Query: 2 PKSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQ 61
P+ KS K EA +P A KS +AK AE + + + + + AK E K
Sbjct: 506 PEKETKSRVKEEAKSPGEA--KSPGEAKSPAEAKSPGEAKSPGEAKSPGEAKSPAEPK-S 562
Query: 62 KVKKESSSDDDSSSEDEKPAPKVAPLKT-SVKNGTTPAKKAKPAPSSSSSDEDSSDEEEE 120
+ +S ++ S +E + PA +P + S +PA+ PA + S ++ S E +
Sbjct: 563 PAEPKSPAEAKSPAEPKSPATVKSPGEAKSPSEAKSPAEAKSPAEAKSPAEAKSPAEAKS 622
Query: 121 VI-------AKKPTKVVVPKKEESSSDEDSSSDEDSSSESD---DEKPAAKVAVPAK-KA 169
AK P V P + +S S+ S ++ S +E+ + K A+V P + K+
Sbjct: 623 PAEAKSPAEAKSPATVKSPGEAKSPSEAKSPAEAKSPAEAKSPAEAKSPAEVKSPGEAKS 682
Query: 170 PAKNGS---VTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEES 226
PA+ S +PA+ PA + S +E E P+A + E AV+ E
Sbjct: 683 PAEPKSPAEAKSPAEVKSPA-EAKSPAEVKSPGEAKSPAAVKSPAEAKSPAAVKSPGEAK 741
Query: 227 SSDDSSSESEDEKPA-----VKVSAPSKVVPAAVKNGA---ADSDSSDSDSSSDEDDDKK 278
S ++ S +E + PA ++V +P K VK GA A++ S + S ++D K
Sbjct: 742 SPGEAKSPAEAKSPAEAKSPIEVKSPEKA-KTPVKEGAKSPAEAKSPEKAKSPVKEDIKP 800
Query: 279 KPATKVAKKL--PAAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKPSAVK----- 331
K +K P K EK++ D +S E+ + T + P VK
Sbjct: 801 PAEAKSPEKAKSPVKEGAKPPEKAKPLDVKSPEAQTPVQEEATVPTDIRPPEQVKSPAKE 860
Query: 332 KSASSDSDDEDSSDSDSEVKKD-KMDVDESDSSEDSDE--EDEKSTKTPQKKVKDVEMVD 388
K+ S + ++ +S+ + K++ K V E +++ + E+EK+ TP+ + K+ + +
Sbjct: 861 KAKSPEKEEAKTSEKVAPKKEEVKSPVKEEVKAKEPPKKVEEEKTLPTPKTEAKESKKDE 920
Query: 389 ASSGKNAPKTPAAQTENE 406
A K APK P + + E
Sbjct: 921 AP--KEAPK-PKVEEKKE 935
Score = 95.5 bits (236), Expect = 4e-19
Identities = 103/430 (23%), Positives = 186/430 (42%), Gaps = 43/430 (10%)
Query: 3 KSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQK 62
KS ++ + E +P A KS + K AE + +V + + + A K E K
Sbjct: 675 KSPGEAKSPAEPKSPAEA--KSPAEVKSPAEAKSPAEVKSPGEAKSPAAVKSPAEAKSPA 732
Query: 63 VKK-----ESSSDDDSSSEDEKPAPKVAPLKT-SVKNGTTPAKKAKPAPSSSSSDEDSSD 116
K +S + S +E + PA +P++ S + TP K+ +P+ + S E +
Sbjct: 733 AVKSPGEAKSPGEAKSPAEAKSPAEAKSPIEVKSPEKAKTPVKEGAKSPAEAKSPEKAKS 792
Query: 117 EEEEVI-----AKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVA-VPAKKAP 170
+E I AK P K P KE + E + + S E+ + P + A VP P
Sbjct: 793 PVKEDIKPPAEAKSPEKAKSPVKEGAKPPEKAKPLDVKSPEA--QTPVQEEATVPTDIRP 850
Query: 171 AKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVKPAVQKKKEESSSDD 230
+ V +PAK+ +P + + + E K+EV K +K +EE +
Sbjct: 851 PEQ--VKSPAKEKAKSPEKEEAKTSEKVAPKKEEVKSPVKEEVKAKEPPKKVEEEKTLPT 908
Query: 231 SSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSD---EDDDKKKPATKVAKK 287
+E+++ K K AP + V+ DS+++ E+ +KK A ++
Sbjct: 909 PKTEAKESK---KDEAPKEAPKPKVEEKKETPTEKPKDSTAEAKKEEAGEKKKAVASEEE 965
Query: 288 LPAAAPIKK----VEKSESSDDESSESSDEENDSKPATTTVAK----PSAVKKSASSDSD 339
PA +K+ EK+E++ E+ ++ +E SKP T K P+A +K D+
Sbjct: 966 TPAKLGVKEEAKPKEKTETTKTEAEDTKAKE-PSKPTETEKPKKEEMPAAPEK---KDTK 1021
Query: 340 DEDSSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQKKVKDVEMVDASSGKNAPKTP 399
+E +++S +K KM+ E+D+ +K P K + +S+ + + P
Sbjct: 1022 EEKTTESRKPEEKPKMEAKVK-------EDDKSLSKEPSKPKTEKAEKSSSTDQKESQPP 1074
Query: 400 AAQTENEGSK 409
TE++ +K
Sbjct: 1075 EKTTEDKATK 1084
Score = 88.2 bits (217), Expect = 6e-17
Identities = 94/369 (25%), Positives = 160/369 (42%), Gaps = 27/369 (7%)
Query: 33 EDEVEKQVSAKKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVK 92
E++ E++++A AE AA +KETK +VK+E+ S ++ S E +P A K
Sbjct: 485 EEKEEEELAAATSPPAEEAASPEKETK-SRVKEEAKSPGEAKSPGEAKSPAEAKSPGEAK 543
Query: 93 N---GTTPAKKAKPAPSSSSSDEDSSDEEEEVIAKKPTKVVVPKKEESSSDEDSSSDEDS 149
+ +P + PA S ++ S E AK P + P +S + S S+ S
Sbjct: 544 SPGEAKSPGEAKSPAEPKSPAEPKSPAE-----AKSPAEPKSPATVKSPGEAKSPSEAKS 598
Query: 150 SSESDDEKPAAKVAVPAK-KAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSAKQ 208
+E+ K A+ PA+ K+PA+ +PA+ PA + S + + AK
Sbjct: 599 PAEA---KSPAEAKSPAEAKSPAE---AKSPAEAKSPAEAKSPATVKSPGEAKSPSEAKS 652
Query: 209 PKKEVAVKPAVQKKKEESSSD-DSSSESEDEKPAVKVSAPSKVVPAAVKNGAADSDSSDS 267
P + A PA K E+ S + S E + PA S PA VK+ A ++
Sbjct: 653 PAE--AKSPAEAKSPAEAKSPAEVKSPGEAKSPAEPKSPAEAKSPAEVKSPAEAKSPAEV 710
Query: 268 DSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDESSESSDEENDSKPATTTVAKP 327
S + K A K + + A +K +++S + S + + + V P
Sbjct: 711 KSPGEA---KSPAAVKSPAEAKSPAAVKSPGEAKSPGEAKSPAEAKSPAEAKSPIEVKSP 767
Query: 328 ----SAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTKTPQK-KVK 382
+ VK+ A S ++ + + S VK+D E+ S E + ++ K P+K K
Sbjct: 768 EKAKTPVKEGAKSPAEAKSPEKAKSPVKEDIKPPAEAKSPEKAKSPVKEGAKPPEKAKPL 827
Query: 383 DVEMVDASS 391
DV+ +A +
Sbjct: 828 DVKSPEAQT 836
Score = 86.7 bits (213), Expect = 2e-16
Identities = 78/321 (24%), Positives = 137/321 (42%), Gaps = 43/321 (13%)
Query: 2 PKSSKKSATKVEAAAPVAAAPKSAKKAKRAAEDEVEKQVSAKKQKIAEVAAKQKKETKLQ 61
P + KS K A +PV K +KAK E Q +++ + ++ K
Sbjct: 800 PPAEAKSPEK--AKSPVKEGAKPPEKAKPLDVKSPEAQTPVQEEATVPTDIRPPEQVKSP 857
Query: 62 KVKKESSSDDDSSSEDEKPAPKVAPLKTSVK---NGTTPAKKAKPAPSSSSSDEDSSDEE 118
+K S + + + EK APK +K+ VK P KK + + + ++ + +
Sbjct: 858 AKEKAKSPEKEEAKTSEKVAPKKEEVKSPVKEEVKAKEPPKKVEEEKTLPTPKTEAKESK 917
Query: 119 EEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTA 178
++ K+ K V +K+E+ +++ S ++ E EK K ++ PAK G V
Sbjct: 918 KDEAPKEAPKPKVEEKKETPTEKPKDSTAEAKKEEAGEK--KKAVASEEETPAKLG-VKE 974
Query: 179 PAKKAQPAPSSSSESEDDDSSEEDEPS-AKQPKKEVAVKPAVQKKKEESSSDDSSSESED 237
AK + ++ +E+ED + E +P+ ++PKKE PA +KK+ + S +
Sbjct: 975 EAKPKEKTETTKTEAEDTKAKEPSKPTETEKPKKE--EMPAAPEKKDTKEEKTTESRKPE 1032
Query: 238 EKPAVKVSAPSKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKV 297
EKP ++ A VK EDD K K P+ +K
Sbjct: 1033 EKPKME---------AKVK----------------EDD-------KSLSKEPSKPKTEKA 1060
Query: 298 EKSESSDDESSESSDEENDSK 318
EKS S+D + S+ ++ + K
Sbjct: 1061 EKSSSTDQKESQPPEKTTEDK 1081
Score = 70.9 bits (172), Expect = 1e-11
Identities = 63/263 (23%), Positives = 115/263 (42%), Gaps = 40/263 (15%)
Query: 2 PKSSKKSATKVEAAAPVAAAPKSAKKA---KRAAEDEVEKQVSAKKQKIAEVAAKQKKET 58
P KS K +A +P K+++K K + V+++V AK E K ++E
Sbjct: 850 PPEQVKSPAKEKAKSPEKEEAKTSEKVAPKKEEVKSPVKEEVKAK-----EPPKKVEEEK 904
Query: 59 KLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGTTPAKKAKPAPSSSSSDEDSSDEE 118
L K E+ + E P PKV K TP +K K + ++ + E++ +++
Sbjct: 905 TLPTPKTEAKESKKDEAPKEAPKPKVEEKKE------TPTEKPKDS-TAEAKKEEAGEKK 957
Query: 119 EEVIAKKPTKVVVPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTA 178
+ V +++ T + KEE+ E + E + +E++D K K P+K
Sbjct: 958 KAVASEEETPAKLGVKEEAKPKEKT---ETTKTEAEDTKA---------KEPSKPTETEK 1005
Query: 179 PAKKAQPAPSSSSESEDDDSSEEDEPSAKQPKKEVAVK------------PAVQKKKEES 226
P K+ PA +++++ ++E +P K PK E VK P +K ++ S
Sbjct: 1006 PKKEEMPAAPEKKDTKEEKTTESRKPEEK-PKMEAKVKEDDKSLSKEPSKPKTEKAEKSS 1064
Query: 227 SSDDSSSESEDEKPAVKVSAPSK 249
S+D S+ ++ K + K
Sbjct: 1065 STDQKESQPPEKTTEDKATKGEK 1087
Score = 65.1 bits (157), Expect = 6e-10
Identities = 86/394 (21%), Positives = 160/394 (39%), Gaps = 27/394 (6%)
Query: 36 VEKQVSAKKQKIAEVAAKQKKETKLQKVKKESSSDDDSSSEDEKPAPKVAPLKTSVKNGT 95
+ + K +++ +V K +KET + + + E + +E+E + + G
Sbjct: 427 ISTHIKVKSEEMIKVVEKSEKETVIVEGQTEEIRVTEGVTEEEDKEAQ-GQEGEEAEEGE 485
Query: 96 TPAKKAKPAPSSSSSDEDSSDEEE-----EVIAKKPTKVVVPKKEESSSDEDSSSDEDSS 150
++ A +S ++E +S E+E + AK P + P + +S ++ S + S
Sbjct: 486 EKEEEELAAATSPPAEEAASPEKETKSRVKEEAKSPGEAKSPGEAKSPAEAKSPGEAKSP 545
Query: 151 SESDDEKPAAKVAVPAK----KAPAKNGSVTAPAKKAQPAPSSSSESEDDDSSEEDEPSA 206
E+ A A P K+PA+ S PA+ PA S S + A
Sbjct: 546 GEAKSPGEAKSPAEPKSPAEPKSPAEAKS---PAEPKSPATVKSPGEAKSPSEAKSPAEA 602
Query: 207 KQPKKEVAVKPAVQKKKEESSSD-DSSSESEDEKPAV-----KVSAPSKV-VPAAVKNGA 259
K P + A PA K E+ S ++ S +E + PA + +PS+ PA K+ A
Sbjct: 603 KSPAE--AKSPAEAKSPAEAKSPAEAKSPAEAKSPATVKSPGEAKSPSEAKSPAEAKSPA 660
Query: 260 ADSDSSDSDSSSD--EDDDKKKPA-TKVAKKLPAAAPIKKVEKSESSDDESSESSDEEND 316
+++ S ++ + K PA K + + A +K +++S + S +
Sbjct: 661 EAKSPAEAKSPAEVKSPGEAKSPAEPKSPAEAKSPAEVKSPAEAKSPAEVKSPGEAKSPA 720
Query: 317 SKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSDEEDEKSTKT 376
+ + P+AVK + S E S ++++ + E S E + ++ K+
Sbjct: 721 AVKSPAEAKSPAAVKSPGEAKSPGEAKSPAEAKSPAEAKSPIEVKSPEKAKTPVKEGAKS 780
Query: 377 PQKKVKDVEMVDASSGKNAPKTPAAQTENEGSKT 410
P + K E S K K PA E +K+
Sbjct: 781 P-AEAKSPEKA-KSPVKEDIKPPAEAKSPEKAKS 812
Score = 49.7 bits (117), Expect = 2e-05
Identities = 54/273 (19%), Positives = 91/273 (32%), Gaps = 6/273 (2%)
Query: 131 VPKKEESSSDEDSSSDEDSSSESDDEKPAAKVAVPAKKAPAKNGSVTAPAKKAQPAPSSS 190
+PK S+ S+E EK V ++ G K+AQ
Sbjct: 421 LPKIPSISTHIKVKSEEMIKVVEKSEKETVIVEGQTEEIRVTEGVTEEEDKEAQGQEGEE 480
Query: 191 SESEDDDSSEEDEPSAKQPKKEVAVKPAVQKK---KEESSSDDSSSESEDEKPAVKVSAP 247
+E ++ EE+ +A P E A P + K KEE+ S + + K + +P
Sbjct: 481 AEEGEE-KEEEELAAATSPPAEEAASPEKETKSRVKEEAKSPGEAKSPGEAKSPAEAKSP 539
Query: 248 SKVVPAAVKNGAADSDSSDSDSSSDEDDDKKKPATKVAKKLPAAAPIKKVEKSESSDDES 307
+ ++ S S E + + K PA KS S
Sbjct: 540 GEAKSPGEAKSPGEAKSPAEPKSPAEPKSPAEAKSPAEPKSPATVKSPGEAKSPSEAKSP 599
Query: 308 SESSDEENDSKPATTTVAKPSAVKKSASSDSDDEDSSDSDSEVKKDKMDVDESDSSEDSD 367
+E+ PA P+ K A + S E S + + + E+ S ++
Sbjct: 600 AEAKSPAEAKSPA--EAKSPAEAKSPAEAKSPAEAKSPATVKSPGEAKSPSEAKSPAEAK 657
Query: 368 EEDEKSTKTPQKKVKDVEMVDASSGKNAPKTPA 400
E + K +V+ + PK+PA
Sbjct: 658 SPAEAKSPAEAKSPAEVKSPGEAKSPAEPKSPA 690
>RO32_XENLA (P51992) Heterogeneous nuclear ribonucleoprotein A3
homolog 2 (hnRNP A3(B))
Length = 385
Score = 110 bits (276), Expect = 9e-24
Identities = 80/255 (31%), Positives = 125/255 (48%), Gaps = 27/255 (10%)
Query: 404 ENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATD-EDGRFKGFGHVEFATAAAA 462
E E + LF+G LSF + F+ G++ D + D + R +GFG V +
Sbjct: 22 EPEQLRKLFIGGLSFETTDDSLREHFEQWGKLTDCVVMRDPQTKRSRGFGFVTY------ 75
Query: 463 QSALEYNGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRGQSQTVFVRGFDKFQGE 522
S +E + + RP ++D R + + +S + G + +FV G E
Sbjct: 76 -SCVEEVDASMSARPHKVD---GRVVEPKRAVSREDSARPGAHLTVKKIFVGGIK----E 127
Query: 523 DDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVNK-------ALELHD 575
D + L+++F G+I I V +D +SG +GFA++ F D ++V+K + LH+
Sbjct: 128 DTEEYHLRDYFEGYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINLHN 187
Query: 576 SDLGGFTLAVDEAKPRDNQGSGGRSGGGRSGGGRGGRFDSGRGGGRGRFGSGGRGGDRGG 635
++ A+ + + + GR GGG + GRGG + G GGG G FG GG G+RGG
Sbjct: 188 CEV---KKALSKQEMQTASAQRGRGGGGSNFMGRGGNYGGGDGGGGGNFGRGGGFGNRGG 244
Query: 636 RGGRG--GGGRGGRG 648
GG G GGG GG G
Sbjct: 245 YGGGGGRGGGYGGGG 259
Score = 45.4 bits (106), Expect = 5e-04
Identities = 25/52 (48%), Positives = 26/52 (49%), Gaps = 1/52 (1%)
Query: 595 GSGGRSGGGRSGGGRGGRFDSGRGGGRGRFGSGGRGGDRGGRGGRGGGGRGG 646
G GG GGG GGRG G G G +G GG GG GG GG G GG
Sbjct: 267 GDGGNYGGGPGYGGRGYGGSPGYGNQGGGYGGGGGGGGAGG-GGYDGYNEGG 317
Score = 43.5 bits (101), Expect = 0.002
Identities = 56/239 (23%), Positives = 89/239 (36%), Gaps = 38/239 (15%)
Query: 409 KTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATD-EDGRFKGFGHVEFATAAAAQSAL- 466
K +FVG + + + ++F+ G++ + + D + G+ +GF V F +
Sbjct: 118 KKIFVGGIKEDTEEYHLRDYFEGYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVV 177
Query: 467 -EYNGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRGQSQTVFVRGFDKFQGEDDI 525
+Y+ L V+ L+++ + + GRG + F+ + G D
Sbjct: 178 QKYHTINLHNCEVKKALSKQE---------MQTASAQRGRGGGGSNFMGRGGNYGGGDGG 228
Query: 526 KSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVNKALELHDSDLGGFTLAV 585
+FG G + G +G Y D + GG
Sbjct: 229 GGG---NFGRGGGFGNRG---GYGGGGGRGGGYGGGGDGYN----------GFGG----- 267
Query: 586 DEAKPRDNQGSGGRSGGGRSG-GGRGGRFDSGRGGGRGRFGSGGRGGDRGGRGGRGGGG 643
D G GGR GG G G +GG + G GGG G+GG G D GG GGG
Sbjct: 268 DGGNYGGGPGYGGRGYGGSPGYGNQGGGYGGGGGGG----GAGGGGYDGYNEGGNFGGG 322
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/79 (34%), Positives = 30/79 (37%), Gaps = 24/79 (30%)
Query: 595 GSGGRSGGGRSGGGRGGRFDSGRGGGRGRFG-------------------SGGRGGDR-- 633
G GG GGG G GG F G G +G +GG GG
Sbjct: 301 GGGGAGGGGYDGYNEGGNFGGGNYNDFGSYGGQQQSNYGPMKAGNFSGRSTGGSGGSSSG 360
Query: 634 ---GGRGGRGGGGRGGRGT 649
GG G GGGG GG G+
Sbjct: 361 PYGGGYGSGGGGGGGGGGS 379
Score = 38.5 bits (88), Expect = 0.057
Identities = 23/42 (54%), Positives = 24/42 (56%), Gaps = 5/42 (11%)
Query: 603 GRSGGGRGGRFDSGRGGGRGRFGSGGRGGDRGGRGGRGGGGR 644
GRS GG GG GGG +GSGG GG GG GG GG R
Sbjct: 348 GRSTGGSGGSSSGPYGGG---YGSGGGGG--GGGGGSYGGRR 384
Score = 34.3 bits (77), Expect = 1.1
Identities = 30/88 (34%), Positives = 34/88 (38%), Gaps = 19/88 (21%)
Query: 549 ESGNVKGFAYLDFSDTNSVNKALELHDSDLGGFTLAVDEAKPRDNQGSGGRSGGGRSGGG 608
E GN G Y DF ++ G F+ R GSGG S G GG
Sbjct: 315 EGGNFGGGNYNDFGSYGGQQQS-NYGPMKAGNFS-------GRSTGGSGGSSSGPYGGG- 365
Query: 609 RGGRFDSGRGGGRGRFGSGGRGGDRGGR 636
+ SG GGG GG GG GGR
Sbjct: 366 ----YGSGGGGG------GGGGGSYGGR 383
>ROA1_MACMU (Q28521) Heterogeneous nuclear ribonucleoprotein A1
(Helix-destabilizing protein) (Single-strand binding
protein) (hnRNP core protein A1)
Length = 319
Score = 110 bits (275), Expect = 1e-23
Identities = 86/265 (32%), Positives = 121/265 (45%), Gaps = 32/265 (12%)
Query: 391 SGKNAPKTPAAQTENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATDEDG-RFK 449
S +PK P E + LF+G LSF + + F+ G + D + D + R +
Sbjct: 1 SKSESPKEP------EQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSR 54
Query: 450 GFGHVEFATAAAAQSALEYNGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRGQSQ 509
GFG V +AT +A+ RP ++D R + + +S + G +
Sbjct: 55 GFGFVTYATVEKVDAAMN-------ARPHKVD---GRVVEPKRAVSREDSQRPGAHLTVK 104
Query: 510 TVFVRGFDKFQGEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVNK 569
+FV G ED + L+++F G+I I + D SG +GFA++ F D NSV+K
Sbjct: 105 KIFVGGIK----EDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHNSVDK 160
Query: 570 ALELHDSDLGGFTLAVDEAKPRDNQGSG-----GRSGGGRSGGGRGGRFDSGRGGGRGRF 624
+ + G V +A + S GRSG G GGGRGG F GG F
Sbjct: 161 IVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGF-----GGNDNF 215
Query: 625 GSGGRGGDRGGRGG-RGGGGRGGRG 648
G GG RGG GG RGGGG GG G
Sbjct: 216 GRGGNFSGRGGFGGSRGGGGYGGSG 240
>ROA3_RAT (Q6URK4) Heterogeneous nuclear ribonucleoprotein A3 (hnRNP
A3)
Length = 379
Score = 108 bits (271), Expect = 3e-23
Identities = 81/250 (32%), Positives = 119/250 (47%), Gaps = 23/250 (9%)
Query: 404 ENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATD-EDGRFKGFGHVEFATAAAA 462
E E + LF+G LSF + F+ G + D + D + R +GFG V +
Sbjct: 30 EPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTY------ 83
Query: 463 QSALEYNGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRGQSQTVFVRGFDKFQGE 522
S +E + + RP ++D R + + +S + G + +FV G E
Sbjct: 84 -SCVEEVDAAMCARPHKVD---GRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIK----E 135
Query: 523 DDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVNKALELHDSDLGGFT 582
D + +L+++F G+I I V +D +SG +GFA++ F D ++V+K + + G
Sbjct: 136 DTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHN 195
Query: 583 LAVDEAKPRDNQGSGG--RSGGGRSGG--GRGGRFDSGRGGGRGRFGSGGRGGDRGGRGG 638
V +A + S G R GG SG GRGG F GGG G FG GG G RGG GG
Sbjct: 196 CEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNF----GGGGGNFGRGGNFGGRGGYGG 251
Query: 639 RGGGGRGGRG 648
GGG RG G
Sbjct: 252 GGGGSRGSYG 261
Score = 46.6 bits (109), Expect = 2e-04
Identities = 67/271 (24%), Positives = 95/271 (34%), Gaps = 50/271 (18%)
Query: 409 KTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATD-EDGRFKGFGHVEF-----ATAAAA 462
K +FVG + + ++ ++F+ G++ + + D + G+ +GF V F
Sbjct: 126 KKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVV 185
Query: 463 QSALEYNGSEL-LQRPVRLDLARERGAYTPNSGAANNSFQKGGR-GQSQTVFVRGFDKFQ 520
Q NG +++ + + G+ G + N +GG G F RG F
Sbjct: 186 QKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRG-GNFG 244
Query: 521 GEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVNKALELHDSDLGG 580
G GS G G GF + N S GG
Sbjct: 245 GRGGYGGGGGGSRGSYGG----------GDGGYNGFG------GDGGNYGGGPGYSSRGG 288
Query: 581 FTLAVDEAKPRDNQGSG-GRSGGGRSGGGRGGRFDSGRGGGRGRFGSGG----------- 628
+ NQG G G GGG G GG F G GG G + G
Sbjct: 289 YG---GGGPGYGNQGGGYGGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYG 345
Query: 629 --RGGDRGGR-------GGRG-GGGRGGRGT 649
+GG GGR GG G GGG GG G+
Sbjct: 346 PMKGGSFGGRSSGSPYGGGYGSGGGSGGYGS 376
Score = 43.5 bits (101), Expect = 0.002
Identities = 25/56 (44%), Positives = 26/56 (45%), Gaps = 2/56 (3%)
Query: 595 GSGGRSGGGRSGGGRGGRFDSGRGGGR--GRFGSGGRGGDRGGRGGRGGGGRGGRG 648
G GG GGG RGG G G G G +G GG G D GG GGG G G
Sbjct: 272 GDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDGYNEGGNFGGGNYGGG 327
>ROA3_MOUSE (Q8BG05) Heterogeneous nuclear ribonucleoprotein A3
(hnRNP A3)
Length = 379
Score = 108 bits (271), Expect = 3e-23
Identities = 81/250 (32%), Positives = 119/250 (47%), Gaps = 23/250 (9%)
Query: 404 ENEGSKTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATD-EDGRFKGFGHVEFATAAAA 462
E E + LF+G LSF + F+ G + D + D + R +GFG V +
Sbjct: 30 EPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTY------ 83
Query: 463 QSALEYNGSELLQRPVRLDLARERGAYTPNSGAANNSFQKGGRGQSQTVFVRGFDKFQGE 522
S +E + + RP ++D R + + +S + G + +FV G E
Sbjct: 84 -SCVEEVDAAMCARPHKVD---GRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIK----E 135
Query: 523 DDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVNKALELHDSDLGGFT 582
D + +L+++F G+I I V +D +SG +GFA++ F D ++V+K + + G
Sbjct: 136 DTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHN 195
Query: 583 LAVDEAKPRDNQGSGG--RSGGGRSGG--GRGGRFDSGRGGGRGRFGSGGRGGDRGGRGG 638
V +A + S G R GG SG GRGG F GGG G FG GG G RGG GG
Sbjct: 196 CEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNF----GGGGGNFGRGGNFGGRGGYGG 251
Query: 639 RGGGGRGGRG 648
GGG RG G
Sbjct: 252 GGGGSRGSYG 261
Score = 46.6 bits (109), Expect = 2e-04
Identities = 67/271 (24%), Positives = 95/271 (34%), Gaps = 50/271 (18%)
Query: 409 KTLFVGNLSFSVQRSDVENFFKDCGEVVDVRLATD-EDGRFKGFGHVEF-----ATAAAA 462
K +FVG + + ++ ++F+ G++ + + D + G+ +GF V F
Sbjct: 126 KKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVV 185
Query: 463 QSALEYNGSEL-LQRPVRLDLARERGAYTPNSGAANNSFQKGGR-GQSQTVFVRGFDKFQ 520
Q NG +++ + + G+ G + N +GG G F RG F
Sbjct: 186 QKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRG-GNFG 244
Query: 521 GEDDIKSSLQEHFGSCGEITRISVPKDFESGNVKGFAYLDFSDTNSVNKALELHDSDLGG 580
G GS G G GF + N S GG
Sbjct: 245 GRGGYGGGGGGSRGSYGG----------GDGGYNGFG------GDGGNYGGGPGYSSRGG 288
Query: 581 FTLAVDEAKPRDNQGSG-GRSGGGRSGGGRGGRFDSGRGGGRGRFGSGG----------- 628
+ NQG G G GGG G GG F G GG G + G
Sbjct: 289 YG---GGGPGYGNQGGGYGGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYG 345
Query: 629 --RGGDRGGR-------GGRG-GGGRGGRGT 649
+GG GGR GG G GGG GG G+
Sbjct: 346 PMKGGSFGGRSSGSPYGGGYGSGGGSGGYGS 376
Score = 43.5 bits (101), Expect = 0.002
Identities = 25/56 (44%), Positives = 26/56 (45%), Gaps = 2/56 (3%)
Query: 595 GSGGRSGGGRSGGGRGGRFDSGRGGGR--GRFGSGGRGGDRGGRGGRGGGGRGGRG 648
G GG GGG RGG G G G G +G GG G D GG GGG G G
Sbjct: 272 GDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDGYNEGGNFGGGNYGGG 327
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.298 0.120 0.311
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,753,602
Number of Sequences: 164201
Number of extensions: 4397765
Number of successful extensions: 119986
Number of sequences better than 10.0: 4670
Number of HSP's better than 10.0 without gapping: 1950
Number of HSP's successfully gapped in prelim test: 2801
Number of HSP's that attempted gapping in prelim test: 26299
Number of HSP's gapped (non-prelim): 34082
length of query: 664
length of database: 59,974,054
effective HSP length: 117
effective length of query: 547
effective length of database: 40,762,537
effective search space: 22297107739
effective search space used: 22297107739
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (22.0 bits)
S2: 69 (31.2 bits)
Lotus: description of TM0135.11